Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	intracellularly cGMP-activated cation channel activity	CNGB1 CNGA1 CNGA3	1.39e-05	7	149	3	GO:0005223
GeneOntologyMolecularFunction	intracellularly cAMP-activated cation channel activity	CNGB1 CNGA1 CNGA3	4.70e-05	10	149	3	GO:0005222
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	ITPR3 CNGB1 CNGA1 CNGA3	1.03e-04	33	149	4	GO:0005217
GeneOntologyMolecularFunction	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	CNGB1 CNGA1 CNGA3	1.10e-04	13	149	3	GO:0005221
GeneOntologyMolecularFunction	cyclic nucleotide-activated monoatomic ion channel activity	CNGB1 CNGA1 CNGA3	1.10e-04	13	149	3	GO:0043855
GeneOntologyMolecularFunction	small GTPase binding	DOCK3 NCKAP1 GIT1 DOCK11 DOCK9 DOCK10 RIN1 DIAPH1 IPO13 RABGGTA	1.52e-04	321	149	10	GO:0031267
GeneOntologyMolecularFunction	cGMP binding	CNGB1 CNGA1 CNGA3	2.12e-04	16	149	3	GO:0030553
GeneOntologyMolecularFunction	structural constituent of muscle	OBSCN ACTN3 MYL9 PLEC	2.93e-04	43	149	4	GO:0008307
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	DOCK3 DOCK11 DOCK9 OBSCN DOCK10 PREX2 RIN1 VAV2	3.49e-04	231	149	8	GO:0005085
GeneOntologyMolecularFunction	GTPase binding	DOCK3 NCKAP1 GIT1 DOCK11 DOCK9 DOCK10 RIN1 DIAPH1 IPO13 RABGGTA	3.81e-04	360	149	10	GO:0051020
GeneOntologyMolecularFunction	calcium channel activity	ITPR3 TRPM8 GRIN3A CNGB1 CNGA1 CNGA3	4.18e-04	129	149	6	GO:0005262
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DOCK3 ARHGAP23 GIT1 DOCK11 DOCK9 OBSCN DOCK10 RALGAPA2 PREX2 RIN1 VAV2 ACAP3	4.30e-04	507	149	12	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DOCK3 ARHGAP23 GIT1 DOCK11 DOCK9 OBSCN DOCK10 RALGAPA2 PREX2 RIN1 VAV2 ACAP3	4.30e-04	507	149	12	GO:0030695
GeneOntologyMolecularFunction	cytoskeletal protein binding	NUSAP1 ANK2 TRAF3IP1 GIT1 CENPE KIF26B OBSCN ACTN4 ACTN3 DDX3X MYL12A MYL9 MTUS1 DIAPH1 TMOD1 PLEC CAMSAP1 CNGA3 PICK1	5.45e-04	1099	149	19	GO:0008092
GeneOntologyMolecularFunction	enzyme regulator activity	DOCK3 ARHGAP23 GIT1 SPOCK1 DOCK11 CIP2A ESR1 DOCK9 NAIP OBSCN DOCK10 PSMD1 RALGAPA2 MAP3K12 PREX2 DDX3X RIN1 SERPINB9 CSNK2B ITIH6 VAV2 ACAP3	8.42e-04	1418	149	22	GO:0030234
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	ITPR3 TRPM8 GRIN3A CNGB1 CNGA1 CNGA3	9.57e-04	151	149	6	GO:0015085
GeneOntologyMolecularFunction	poly(A) binding	DDX3X KHDRBS1 PABPC3	1.29e-03	29	149	3	GO:0008143
GeneOntologyBiologicalProcess	visual perception	SPATA7 LAMB2 GRM8 ABCC6 SLC4A10 CNGB1 CNGA1 CNGA3 RABGGTA	3.92e-05	230	146	9	GO:0007601
GeneOntologyBiologicalProcess	sensory perception of light stimulus	SPATA7 LAMB2 GRM8 ABCC6 SLC4A10 CNGB1 CNGA1 CNGA3 RABGGTA	4.34e-05	233	146	9	GO:0050953
GeneOntologyBiologicalProcess	basal protein localization	NCKAP1 ERBIN	4.98e-05	2	146	2	GO:0045175
GeneOntologyBiologicalProcess	protein localization to M-band	ANK2 OBSCN	4.98e-05	2	146	2	GO:0036309
GeneOntologyBiologicalProcess	positive regulation of organelle organization	NUSAP1 CARMIL2 ATRX NCKAP1 GIT1 CENPE NCAPH2 TERF2 BID LIG4 VPS13D CDK1 ATM PLEK	5.93e-05	574	146	14	GO:0010638
GeneOntologyBiologicalProcess	response to wounding	CARMIL2 GIT1 LAMB2 INPP5F AP3B1 ITGB4 MMRN1 MYL12A MYOF MYL9 CDK1 PLEC PLEK VAV2 CNTF	6.98e-05	659	146	15	GO:0009611
GeneOntologyBiologicalProcess	protein localization to organelle	SPATA7 EMC1 ANK2 ATRX GIT1 ESR1 OBSCN AP3B1 TERF2 DDX3X BID PIKFYVE VPS13D VPS13A TTC21B DIAPH1 NUP133 IPO13 CDK1 CNGB1	8.80e-05	1091	146	20	GO:0033365
GeneOntologyBiologicalProcess	muscle cell development	ANK2 OBSCN ACTN4 ACTN3 MYOF MYL9 TMOD1 CDK1 PLEC	9.78e-05	259	146	9	GO:0055001
GeneOntologyBiologicalProcess	cellular anatomical entity morphogenesis	ANK2 OBSCN ITGB4 PIKFYVE MYL9 TMOD1 PLEC	1.25e-04	156	146	7	GO:0032989
GeneOntologyBiologicalProcess	cellular component assembly involved in morphogenesis	ANK2 OBSCN ITGB4 PIKFYVE MYL9 TMOD1 PLEC	1.25e-04	156	146	7	GO:0010927
GeneOntologyBiologicalProcess	positive regulation of chromosome organization	ATRX NCAPH2 TERF2 LIG4 CDK1 ATM	1.54e-04	113	146	6	GO:2001252
GeneOntologyBiologicalProcess	regulation of organelle organization	NUSAP1 SMG1 CARMIL2 TRAF3IP1 ATRX NCKAP1 GIT1 CENPE ESR1 NCAPH2 TERF2 BID PIKFYVE LIG4 VPS13D DIAPH1 TMOD1 CDK1 ATM PLEK CAMSAP1 PICK1	1.92e-04	1342	146	22	GO:0033043
GeneOntologyCellularComponent	intracellular cyclic nucleotide activated cation channel complex	CNGB1 CNGA1 CNGA3	1.27e-05	7	151	3	GO:0017071
GeneOntologyCellularComponent	rod photoreceptor outer segment	SPATA7 CNGB1 CNGA1	3.01e-05	9	151	3	GO:0120200
GeneOntologyCellularComponent	hemidesmosome	ERBIN ITGB4 PLEC	5.84e-05	11	151	3	GO:0030056
GeneOntologyCellularComponent	axon	GIT1 SPOCK1 ESR1 ROR1 INPP5F AP3B1 TERF2 MAP3K12 ARMCX3 RUFY3 SACS SLC4A10 PLEC CNGB1 CNGA1 CNGA3 ACAP3 CNTF	7.94e-05	891	151	18	GO:0030424
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	SPATA7 TRAF3IP1 DNAH2 AP3B1 TERF2 ARMCX3 DNAH12 HYDIN RSPH10B CNTF	1.06e-04	317	151	10	GO:0032838
GeneOntologyCellularComponent	Z disc	ANK2 OBSCN ACTN4 ACTN3 MYL12A MYL9 PLEC	1.16e-04	151	151	7	GO:0030018
GeneOntologyCellularComponent	I band	ANK2 OBSCN ACTN4 ACTN3 MYL12A MYL9 PLEC	2.08e-04	166	151	7	GO:0031674
GeneOntologyCellularComponent	cytoplasmic region	SPATA7 TRAF3IP1 DNAH2 AP3B1 TERF2 ARMCX3 DNAH12 HYDIN RSPH10B CNTF	2.96e-04	360	151	10	GO:0099568
GeneOntologyCellularComponent	sarcomere	ANK2 OBSCN ACTN4 ACTN3 MYL12A MYL9 TMOD1 PLEC	4.66e-04	249	151	8	GO:0030017
GeneOntologyCellularComponent	myofibril	ANK2 OBSCN ACTN4 ACTN3 MYL12A MYL9 TMOD1 PLEC	8.50e-04	273	151	8	GO:0030016
GeneOntologyCellularComponent	nuclear membrane	AHCTF1 ERBIN ITGB4 ITPR3 MINDY3 MYOF OSBPL6 NUP133 PHLPP1	1.01e-03	349	151	9	GO:0031965
GeneOntologyCellularComponent	contractile muscle fiber	ANK2 OBSCN ACTN4 ACTN3 MYL12A MYL9 TMOD1 PLEC	1.25e-03	290	151	8	GO:0043292
GeneOntologyCellularComponent	myofilament	OBSCN ACTN3 TMOD1	1.57e-03	32	151	3	GO:0036379
HumanPheno	Aplasia of the bladder	ITGB4 FREM2 PLEC	1.17e-05	5	55	3	HP:0010477
Domain	ARM-type_fold	DOCK3 SMG1 DOCK11 CIP2A DOCK9 PSMD1 RALGAPA2 AP3B1 ARMCX3 DIAPH1 IPO13 ATM STKLD1 HECTD1	6.25e-07	339	150	14	IPR016024
Domain	DHR-1_domain	DOCK3 DOCK11 DOCK9 DOCK10	1.26e-06	11	150	4	IPR027007
Domain	DHR_2	DOCK3 DOCK11 DOCK9 DOCK10	1.26e-06	11	150	4	PS51651
Domain	DHR_1	DOCK3 DOCK11 DOCK9 DOCK10	1.26e-06	11	150	4	PS51650
Domain	DHR-2	DOCK3 DOCK11 DOCK9 DOCK10	1.26e-06	11	150	4	PF06920
Domain	DOCK	DOCK3 DOCK11 DOCK9 DOCK10	1.26e-06	11	150	4	IPR026791
Domain	DOCK_C	DOCK3 DOCK11 DOCK9 DOCK10	1.26e-06	11	150	4	IPR010703
Domain	DOCK-C2	DOCK3 DOCK11 DOCK9 DOCK10	1.26e-06	11	150	4	PF14429
Domain	DHR-2	DOCK3 DOCK11 DOCK9 DOCK10	1.26e-06	11	150	4	IPR027357
Domain	PH	DOCK11 DOCK9 OBSCN DOCK10 PREX2 OSBPL6 PHLPP1 PLEK VAV2 PLEKHA8 ACAP3	2.48e-06	229	150	11	PF00169
Domain	PH	ARHGAP23 DOCK11 DOCK9 OBSCN DOCK10 PREX2 OSBPL6 PHLPP1 PLEK VAV2 PLEKHA8 ACAP3	2.60e-06	278	150	12	SM00233
Domain	PH_DOMAIN	ARHGAP23 DOCK11 DOCK9 OBSCN DOCK10 PREX2 OSBPL6 PHLPP1 PLEK VAV2 PLEKHA8 ACAP3	2.70e-06	279	150	12	PS50003
Domain	PH_domain	ARHGAP23 DOCK11 DOCK9 OBSCN DOCK10 PREX2 OSBPL6 PHLPP1 PLEK VAV2 PLEKHA8 ACAP3	2.80e-06	280	150	12	IPR001849
Domain	DUF3398	DOCK11 DOCK9 DOCK10	9.98e-06	6	150	3	PF11878
Domain	DOCK_C/D_N	DOCK11 DOCK9 DOCK10	9.98e-06	6	150	3	IPR021816
Domain	SPIN-2	SPIN2A SPIN2B	6.41e-05	2	150	2	IPR029564
Domain	ATM/Tel1	SMG1 ATM	6.41e-05	2	150	2	IPR015519
Domain	-	ARHGAP23 DOCK11 DOCK9 OBSCN DOCK10 PREX2 OSBPL6 PHLPP1 PLEK VAV2 PLEKHA8 ACAP3	7.70e-05	391	150	12	2.30.29.30
Domain	PH_dom-like	ARHGAP23 DOCK11 DOCK9 OBSCN DOCK10 PREX2 OSBPL6 PHLPP1 PLEK VAV2 PLEKHA8 ACAP3	1.72e-04	426	150	12	IPR011993
Domain	VPS13	VPS13D VPS13A	1.91e-04	3	150	2	IPR026847
Domain	VPS13_mid_rpt	VPS13D VPS13A	1.91e-04	3	150	2	PF16910
Domain	VPS13	VPS13D VPS13A	1.91e-04	3	150	2	PF16908
Domain	VPS13_N2	VPS13D VPS13A	1.91e-04	3	150	2	IPR031646
Domain	VPS13_mid_rpt	VPS13D VPS13A	1.91e-04	3	150	2	IPR031642
Domain	cNMP-bd_CS	CNGB1 CNGA1 CNGA3	2.63e-04	16	150	3	IPR018488
Domain	AT_hook	AHCTF1 KMT2C DOT1L	2.63e-04	16	150	3	PF02178
Domain	CH	ACTN4 ACTN3 PLEC CAMSAP1 VAV2	3.03e-04	73	150	5	PS50021
Domain	DUF1605	DHX8 DQX1 DHX32	3.18e-04	17	150	3	IPR011709
Domain	OB_NTP_bind	DHX8 DQX1 DHX32	3.18e-04	17	150	3	PF07717
Domain	ARM-like	SMG1 CIP2A DOCK10 PSMD1 AP3B1 ARMCX3 IPO13 STKLD1 HECTD1	3.40e-04	270	150	9	IPR011989
Domain	CH-domain	ACTN4 ACTN3 PLEC CAMSAP1 VAV2	3.43e-04	75	150	5	IPR001715
Domain	HA2	DHX8 DQX1 DHX32	3.79e-04	18	150	3	SM00847
Domain	HA2	DHX8 DQX1 DHX32	3.79e-04	18	150	3	PF04408
Domain	Helicase-assoc_dom	DHX8 DQX1 DHX32	3.79e-04	18	150	3	IPR007502
Domain	SHR-BD	VPS13D VPS13A	3.80e-04	4	150	2	IPR009543
Domain	CLZ	CNGA1 CNGA3	3.80e-04	4	150	2	PF16526
Domain	VPS13_C	VPS13D VPS13A	3.80e-04	4	150	2	PF16909
Domain	CLZ_dom	CNGA1 CNGA3	3.80e-04	4	150	2	IPR032406
Domain	VPS13_C	VPS13D VPS13A	3.80e-04	4	150	2	IPR031645
Domain	SHR-BD	VPS13D VPS13A	3.80e-04	4	150	2	PF06650
Domain	SPIN/Ssty	SPIN2A SPIN2B	6.31e-04	5	150	2	IPR003671
Domain	Spin-Ssty	SPIN2A SPIN2B	6.31e-04	5	150	2	PF02513
Domain	FATC	SMG1 ATM	6.31e-04	5	150	2	PF02260
Domain	DEP	PREX2 PIKFYVE PLEK	6.99e-04	22	150	3	PF00610
Domain	DEP	PREX2 PIKFYVE PLEK	6.99e-04	22	150	3	PS50186
Domain	DEP	PREX2 PIKFYVE PLEK	6.99e-04	22	150	3	SM00049
Domain	DEP_dom	PREX2 PIKFYVE PLEK	7.99e-04	23	150	3	IPR000591
Domain	ACTININ_2	ACTN4 ACTN3 PLEC	7.99e-04	23	150	3	PS00020
Domain	ACTININ_1	ACTN4 ACTN3 PLEC	7.99e-04	23	150	3	PS00019
Domain	Actinin_actin-bd_CS	ACTN4 ACTN3 PLEC	7.99e-04	23	150	3	IPR001589
Domain	EFhand_Ca_insen	ACTN4 ACTN3	9.41e-04	6	150	2	PF08726
Domain	EF-hand_Ca_insen	ACTN4 ACTN3	9.41e-04	6	150	2	IPR014837
Domain	FAT	SMG1 ATM	9.41e-04	6	150	2	PS51189
Domain	FATC	SMG1 ATM	9.41e-04	6	150	2	PS51190
Domain	FATC_dom	SMG1 ATM	9.41e-04	6	150	2	IPR003152
Domain	PIK_FAT	SMG1 ATM	9.41e-04	6	150	2	IPR014009
Domain	FATC	SMG1 ATM	9.41e-04	6	150	2	SM01343
Domain	AT_hook	AHCTF1 KMT2C DOT1L	1.29e-03	27	150	3	SM00384
Domain	AT_hook_DNA-bd_motif	AHCTF1 KMT2C DOT1L	1.29e-03	27	150	3	IPR017956
Domain	CAMSAP_CH	CAMSAP1 VAV2	1.31e-03	7	150	2	PF11971
Domain	CAMSAP_CH	CAMSAP1 VAV2	1.31e-03	7	150	2	IPR022613
Domain	Spectrin_repeat	ACTN4 ACTN3 PLEC	1.59e-03	29	150	3	IPR002017
Domain	His_Pase_clade-2	ACP6 MINPP1	1.74e-03	8	150	2	IPR000560
Domain	Chorein_N	VPS13D VPS13A	1.74e-03	8	150	2	PF12624
Domain	Calx_beta	ITGB4 FREM2	1.74e-03	8	150	2	SM00237
Domain	VPS13_N	VPS13D VPS13A	1.74e-03	8	150	2	IPR026854
Domain	His_Phos_2	ACP6 MINPP1	1.74e-03	8	150	2	PF00328
Domain	CH	ACTN4 ACTN3 PLEC VAV2	1.85e-03	65	150	4	SM00033
Domain	HELICASE_CTER	ATRX DDX3X DHX8 DQX1 DHX32	1.87e-03	109	150	5	PS51194
Domain	HELICASE_ATP_BIND_1	ATRX DDX3X DHX8 DQX1 DHX32	1.87e-03	109	150	5	PS51192
Domain	HMGI/Y_DNA-bd_CS	AHCTF1 KMT2C DOT1L	1.94e-03	31	150	3	IPR000637
Domain	Abhydrolase_1	SERHL2 SERHL LIPK	1.94e-03	31	150	3	PF00561
Domain	Helicase_ATP-bd	ATRX DDX3X DHX8 DQX1 DHX32	1.95e-03	110	150	5	IPR014001
Domain	SPEC	ACTN4 ACTN3 PLEC	2.12e-03	32	150	3	SM00150
Domain	CNMP_BINDING_1	CNGB1 CNGA1 CNGA3	2.12e-03	32	150	3	PS00888
Domain	CNMP_BINDING_2	CNGB1 CNGA1 CNGA3	2.12e-03	32	150	3	PS00889
Domain	Spectrin/alpha-actinin	ACTN4 ACTN3 PLEC	2.12e-03	32	150	3	IPR018159
Domain	Calx_beta	ITGB4 FREM2	2.22e-03	9	150	2	IPR003644
Domain	Calx-beta	ITGB4 FREM2	2.22e-03	9	150	2	PF03160
Domain	Ion_trans_dom	ITPR3 TRPM8 CNGB1 CNGA1 CNGA3	2.27e-03	114	150	5	IPR005821
Domain	Ion_trans	ITPR3 TRPM8 CNGB1 CNGA1 CNGA3	2.27e-03	114	150	5	PF00520
Domain	AB_hydrolase_1	SERHL2 SERHL LIPK	2.32e-03	33	150	3	IPR000073
Domain	CH	ACTN4 ACTN3 PLEC VAV2	2.43e-03	70	150	4	PF00307
Domain	cNMP	CNGB1 CNGA1 CNGA3	2.53e-03	34	150	3	SM00100
Domain	cNMP_binding	CNGB1 CNGA1 CNGA3	2.53e-03	34	150	3	PF00027
Domain	-	ACTN4 ACTN3 PLEC VAV2	2.56e-03	71	150	4	1.10.418.10
Domain	cNMP-bd_dom	CNGB1 CNGA1 CNGA3	2.75e-03	35	150	3	IPR000595
Domain	CNMP_BINDING_3	CNGB1 CNGA1 CNGA3	2.75e-03	35	150	3	PS50042
Domain	cNMP-bd-like	CNGB1 CNGA1 CNGA3	3.49e-03	38	150	3	IPR018490
Domain	GDS_CDC24_CS	OBSCN PREX2 VAV2	3.75e-03	39	150	3	IPR001331
Domain	-	CARMIL2 NAIP LRRC69 ERBIN TMOD1 PHLPP1 RABGGTA LRRC23	4.46e-03	321	150	8	3.80.10.10
Domain	L_dom-like	CARMIL2 NAIP LRRC69 ERBIN TMOD1 PHLPP1 RABGGTA LRRC23	5.07e-03	328	150	8	IPR032675
Domain	-	SPOCK1 C1orf87 ACTN4 ACTN3 MYL12A MINDY3 MYL9	5.20e-03	261	150	7	1.10.238.10
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DNAH12	5.47e-03	14	150	2	IPR024317
Domain	Dynein_heavy_dom-2	DNAH2 DNAH12	5.47e-03	14	150	2	IPR013602
Domain	DHC_N2	DNAH2 DNAH12	5.47e-03	14	150	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH2 DNAH12	5.47e-03	14	150	2	IPR011704
Domain	K_chnl_volt-dep_EAG/ELK/ERG	CNGA1 CNGA3	5.47e-03	14	150	2	IPR003938
Domain	AAA_8	DNAH2 DNAH12	5.47e-03	14	150	2	PF12780
Domain	AAA_5	DNAH2 DNAH12	5.47e-03	14	150	2	PF07728
Pathway	REACTOME_RAC1_GTPASE_CYCLE	DOCK3 NCKAP1 ARHGAP23 GIT1 DOCK11 DOCK9 DOCK10 ERBIN PREX2 VAV2	3.00e-06	184	117	10	M41809
Pathway	PID_CDC42_REG_PATHWAY	GIT1 DOCK11 DOCK9 DOCK10 VAV2	4.36e-06	30	117	5	M83
Pathway	REACTOME_RAC2_GTPASE_CYCLE	DOCK3 NCKAP1 GIT1 DOCK10 ERBIN ARMCX3 VAV2	8.25e-06	88	117	7	M41810
Pathway	KEGG_REGULATION_OF_ACTIN_CYTOSKELETON	NCKAP1 GIT1 ACTN4 ACTN3 ITGB4 MYL12A PIKFYVE MYL9 DIAPH1 VAV2	1.10e-05	213	117	10	M18306
Pathway	REACTOME_RAC1_GTPASE_CYCLE	NCKAP1 ARHGAP23 GIT1 DOCK11 DOCK9 DOCK10 ERBIN PREX2 VAV2	1.49e-05	175	117	9	MM15599
Pathway	REACTOME_RHO_GTPASE_CYCLE	DOCK3 NCKAP1 ARHGAP23 GIT1 DOCK11 DOCK9 OBSCN DOCK10 ERBIN ARMCX3 PREX2 KCTD3 DIAPH1 VAV2	2.13e-05	450	117	14	M27078
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	NCKAP1 ARHGAP23 GIT1 CENPE DOCK11 DOCK9 AHCTF1 OBSCN DOCK10 ERBIN ARMCX3 PREX2 MYL12A MYL9 DIAPH1 NUP133 VAV2	2.46e-05	649	117	17	MM15690
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DOCK3 NCKAP1 ARHGAP23 GIT1 CENPE DOCK11 DOCK9 AHCTF1 OBSCN DOCK10 ERBIN ARMCX3 PREX2 MYL9 KCTD3 DIAPH1 NUP133 VAV2	2.58e-05	720	117	18	M41838
Pathway	REACTOME_RAC2_GTPASE_CYCLE	NCKAP1 GIT1 DOCK10 ERBIN ARMCX3 VAV2	8.39e-05	87	117	6	MM15600
Pathway	WP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA	ATRX ERBIN KMT2C MORF4L1 ATM	2.01e-04	65	117	5	M39682
Pathway	KEGG_FOCAL_ADHESION	LAMB2 ACTN4 ACTN3 ITGB4 MYL12A MYL9 DIAPH1 VAV2	2.51e-04	199	117	8	M7253
Pathway	WP_STRIATED_MUSCLE_CONTRACTION_PATHWAY	ACTN4 ACTN3 MYL9 TMOD1	2.68e-04	38	117	4	M39549
Pathway	REACTOME_RHO_GTPASE_CYCLE	NCKAP1 ARHGAP23 GIT1 DOCK11 DOCK9 OBSCN DOCK10 ERBIN ARMCX3 PREX2 DIAPH1 VAV2	2.85e-04	439	117	12	MM15595
Pathway	REACTOME_CDC42_GTPASE_CYCLE	GIT1 DOCK11 DOCK9 DOCK10 PREX2 KCTD3 VAV2	3.06e-04	155	117	7	M41808
Pathway	WP_NEPHROTIC_SYNDROME	LAMB2 ACTN4 ITGB4 TTC21B	5.16e-04	45	117	4	M39864
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK3 ARHGAP23 PPFIBP1 CIP2A RALGAPA2 FAN1 PIKFYVE MYOF VPS13D SACS CDK13 TTC21B ADGRF5 GRIN3A HECTD1	5.15e-09	493	152	15	15368895
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	NUSAP1 CCDC22 EMC1 CIP2A PSMD1 ACTN4 AP3B1 TERF2 ERBIN NSD3 FAN1 ITPR3 CNNM3 SH2D4A MTUS1 KCTD3 VPS13A NUP133 PHLPP1 CDK1 TOP3B	6.92e-09	1049	152	21	27880917
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NCOA6 EMC1 CARMIL2 NCKAP1 GIT1 DOCK11 KIF26B PPFIBP1 INPP5F ERBIN DDX3X NSD3 VPS13D MTUS1 OSBPL6 PLEC CAMSAP1 HECTD1 EDRF1	8.21e-09	861	152	19	36931259
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DOCK3 ANK2 TRAF3IP1 ATRX GIT1 PPFIBP1 ZNF343 PSMD1 ACTN4 RNF40 NCAPH2 RUFY3 DDX3X FAN1 CS KHDRBS1 SACS CSNK2B MORF4L1 ATM PLEC HECTD1 PICK1	1.00e-08	1285	152	23	35914814
Pubmed	Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1.	DOCK9 ERBIN ITGB4 DDX3X DHX8 RIN1 VAV2	1.49e-08	65	152	7	18729074
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 NCOA6 MGAT4B DOCK9 OBSCN LAMB2 RNF40 RALGAPA2 ITGB4 NSD3 ITPR3 PIKFYVE KMT2C MYOF CDK13 PLEC DOT1L CAMSAP1 HECTD1 TOP3B PICK1	1.70e-08	1105	152	21	35748872
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	SPATA7 TRAF3IP1 ATRX NCKAP1 GIT1 PPFIBP1 CIP2A ACTN4 NCAPH2 AP3B1 RIN1 CS SH2D4A CSNK2B KCTD3 TTC21B OSBPL6 NUP133 IPO13 PLEC EDRF1 RSPH10B	7.68e-08	1321	152	22	27173435
Pubmed	Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.	DOCK11 DOCK9 DOCK10	8.18e-08	3	152	3	32241915
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	NCKAP1 CIP2A PSMD1 ACTN4 AP3B1 DDX3X MYL12A USP5 KHDRBS1 CSNK2B DIAPH1 NUP133 CDK1 PLEC HECTD1	1.51e-07	638	152	15	33239621
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	CCDC22 GIT1 PPFIBP1 DDX3X PIKFYVE TTC21B NUP133 CDK1 DOT1L CAMSAP1	1.75e-07	251	152	10	29778605
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SMG1 ANK2 GIT1 DOCK9 OBSCN PSMD1 ACTN4 ACTN3 MORF4L1 NUP133 MED12L PLEC VAV2	3.20e-07	497	152	13	23414517
Pubmed	Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1.	CNGB1 CNGA1 CNGA3	3.26e-07	4	152	3	15634774
Pubmed	Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.	DOCK3 DOCK11 DOCK9 DOCK10	3.39e-07	14	152	4	12432077
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	KIF26B PPFIBP1 CIP2A ACTN4 ERBIN VPS13D MTUS1 CAMSAP1 HECTD1	3.84e-07	209	152	9	36779422
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	CCDC22 RNF40 URB2 ARMCX3 RUFY3 ITPR3 CNNM3 NUP133 CAMSAP1 HECTD1	5.62e-07	285	152	10	32838362
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SMG1 ATRX GIT1 DOCK11 RNF40 DDX3X ITPR3 CSNK2B NUP133 CDK1 CAMSAP1 HECTD1	5.98e-07	440	152	12	34244565
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NUSAP1 B4GALT7 EMC1 ATRX NCKAP1 PPFIBP1 ESR1 AHCTF1 LAMB2 URB2 AP3B1 TERF2 ERBIN NSD3 DHX8 MYL12A KMT2C MYOF CDK13 MORF4L1 KCTD3 EDRF1	6.43e-07	1497	152	22	31527615
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SMG1 NCOA6 PPFIBP1 DOCK9 DOCK10 ERBIN KMT2C MYOF PHLPP1	7.12e-07	225	152	9	12168954
Pubmed	The heteromeric cyclic nucleotide-gated channel adopts a 3A:1B stoichiometry.	CNGB1 CNGA1 CNGA3	8.13e-07	5	152	3	12432397
Pubmed	Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.	DOCK11 DOCK9 DOCK10	8.13e-07	5	152	3	15710388
Pubmed	53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.	TERF2 LIG4 ATM	8.13e-07	5	152	3	18931659
Pubmed	Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.	GIT1 ITGB4 RIN1 PHLPP1 CDK1 PLEC	9.91e-07	75	152	6	15951569
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	EMC1 NCKAP1 GIT1 PPFIBP1 PSMD1 ACTN4 RNF40 AP3B1 ARMCX3 DDX3X DHX8 MYL12A USP5 CDK13 CSNK2B MORF4L1 DIAPH1 CDK1 PLEC HECTD1 GPN3	1.02e-06	1415	152	21	28515276
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CARMIL2 ANK2 NCKAP1 ARHGAP23 GIT1 ACTN4 ACTN3 AP3B1 ERBIN RUFY3 MYL12A RIN1 USP5 CS KHDRBS1 SACS PABPC3 OSBPL6 SLC4A10 TMOD1 PLEC	1.21e-06	1431	152	21	37142655
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SMG1 ANK2 ATRX SPOCK1 DNAH2 PSMD1 ACTN4 ACTN3 TERF2 ERBIN LIG4 KHDRBS1 SACS CDK13 PABPC3 VPS13A ATM PLEC ITIH6 TOP3B PICK1	1.37e-06	1442	152	21	35575683
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	CENPE PREX2 ITPR3 SH2D4A SACS HYDIN	1.45e-06	80	152	6	19389623
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	NUSAP1 NCKAP1 GIT1 LAMB2 PSMD1 ACTN4 AP3B1 ARMCX3 DDX3X MYL12A USP5 CS SH2D4A MYL9 CSNK2B DIAPH1 NUP133 CDK1 PLEC HECTD1 RABGGTA	1.58e-06	1455	152	21	22863883
Pubmed	A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.	ACTN4 ACTN3 MYL12A DIAPH1 PLEC	1.58e-06	45	152	5	22114352
Pubmed	The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.	DOCK11 DOCK9 DOCK10	1.62e-06	6	152	3	25851601
Pubmed	cGMP and cyclic nucleotide-gated channels participate in mouse sperm capacitation.	CNGB1 CNGA1 CNGA3	1.62e-06	6	152	3	22192355
Pubmed	DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.	TERF2 LIG4 ATM	1.62e-06	6	152	3	15968270
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	NCKAP1 CENPE DOCK11 DOCK9 OBSCN KMT2C VPS13D DNAH12 RNFT2 ATM TOP3B HYDIN	2.12e-06	497	152	12	36774506
Pubmed	Functional proteomics mapping of a human signaling pathway.	SMG1 NCOA6 ATRX LAMB2 PSMD1 ERBIN DDX3X USP5 KHDRBS1 CDK13 DIAPH1 PLEC CAMSAP1	2.20e-06	591	152	13	15231748
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	ACP6 EMC1 ATRX NCKAP1 GIT1 PPFIBP1 CDIN1 PSMD1 AP3B1 DDX3X MYL12A CNNM3 KMT2C LIG4 SH2D4A CSNK2B MORF4L1 NUP133 CNTF	3.63e-06	1284	152	19	17353931
Pubmed	Defining the membrane proteome of NK cells.	SLC11A2 CARMIL2 GIT1 CENPE DOCK9 DOCK10 PSMD1 RNF40 NCAPH2 AP3B1 ITPR3 CNNM3 SERPINB9 KHDRBS1 PREP NUP133 CDK1 PLEK	3.83e-06	1168	152	18	19946888
Pubmed	BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming.	AP3B1 DDX3X BID PABPC3 CDK1	4.35e-06	55	152	5	33067418
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	EMC1 CIP2A LAMB2 PSMD1 ACTN4 NCAPH2 AP3B1 ARMCX3 ITPR3 CNNM3 USP5 PREP KCTD3 NUP133 CDK1 HECTD1	6.22e-06	974	152	16	28675297
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NCKAP1 AHCTF1 PSMD1 ACTN4 URB2 DHX8 ITPR3 USP5 PREP NUP133 ATM PLEC HECTD1	6.46e-06	653	152	13	22586326
Pubmed	A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.	ANK2 PPFIBP1 ACTN4 MINDY3 ADGRF5	6.72e-06	60	152	5	19075228
Pubmed	The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.	SPATA7 GTSF1 PSMD1 ACTN4 MYL12A MYL9 KCTD3 HECTD1	7.14e-06	225	152	8	25277244
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	ATRX AHCTF1 TERF2 ARMCX3 KMT2C CDK13 CSNK2B MORF4L1 NUP133 KIAA1958 HYDIN	7.51e-06	469	152	11	27634302
Pubmed	International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.	CNGB1 CNGA1 CNGA3	9.60e-06	10	152	3	16382102
Pubmed	Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.	ACTN4 ACTN3 TMOD1	9.60e-06	10	152	3	20368620
Pubmed	A human MAP kinase interactome.	KIF26B LAMB2 PSMD1 ACTN4 ERBIN ITGB4 NSD3 KMT2C SH2D4A KHDRBS1 PLEC	1.05e-05	486	152	11	20936779
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	ATRX PSMD1 AP3B1 DHX8 BID KHDRBS1 MORF4L1 DIAPH1 MED12L CDK1 ATM PLEC	1.05e-05	582	152	12	20467437
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	EMC1 LAMB2 PSMD1 ACTN4 URB2 DDX3X DHX8 ITPR3 CNNM3 CS KHDRBS1 SACS CSNK2B NUP133 CDK1 PLEC	1.16e-05	1024	152	16	24711643
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	SPOCK1 AGR2 PSMD1 ACTN4 AP3B1 DDX3X MYOF USP5 CS KHDRBS1 DIAPH1 PLEC HYDIN VAV2	1.33e-05	807	152	14	30575818
Pubmed	SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress.	SMG1 ATM	1.90e-05	2	152	2	31565865
Pubmed	ATM-mediated NuSAP phosphorylation induces mitotic arrest.	NUSAP1 ATM	1.90e-05	2	152	2	21130744
Pubmed	Identification of Serhl, a new member of the serine hydrolase family induced by passive stretch of skeletal muscle in vivo.	SERHL2 SERHL	1.90e-05	2	152	2	11352564
Pubmed	Epidermolysis bullosa with congenital pyloric atresia: novel mutations in the beta 4 integrin gene (ITGB4) and genotype/phenotype correlations.	ITGB4 PLEC	1.90e-05	2	152	2	11328943
Pubmed	Telomere Loop Dynamics in Chromosome End Protection.	TERF2 ATM	1.90e-05	2	152	2	30033372
Pubmed	hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.	SMG1 ATM	1.90e-05	2	152	2	18332866
Pubmed	Juxtacrine Activity of Estrogen Receptor α in Uterine Stromal Cells is Necessary for Estrogen-Induced Epithelial Cell Proliferation.	AMHR2 ESR1	1.90e-05	2	152	2	28827707
Pubmed	Phosphorylation of NuSAP by Cdk1 regulates its interaction with microtubules in mitosis.	NUSAP1 CDK1	1.90e-05	2	152	2	22101338
Pubmed	Identification of a novel LXXLL motif in α-actinin 4-spliced isoform that is critical for its interaction with estrogen receptor α and co-activators.	ESR1 ACTN4	1.90e-05	2	152	2	22908231
Pubmed	Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin.	ITGB4 PLEC	1.90e-05	2	152	2	15817481
Pubmed	DDX3X functionally and physically interacts with Estrogen Receptor-alpha.	ESR1 DDX3X	1.90e-05	2	152	2	35121200
Pubmed	Phosphorylation of the Src substrate Sam68 by Cdc2 during mitosis.	KHDRBS1 CDK1	1.90e-05	2	152	2	9315091
Pubmed	Polymorphisms of alpha-actinin-3 and ciliary neurotrophic factor in national-level Italian athletes.	ACTN3 CNTF	1.90e-05	2	152	2	23676962
Pubmed	Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma.	ATRX ATM	1.90e-05	2	152	2	29378238
Pubmed	Structural basis of the partially open central gate in the human CNGA1/CNGB1 channel explained by additional density for calmodulin in cryo-EM map.	CNGB1 CNGA1	1.90e-05	2	152	2	34971760
Pubmed	Gene therapy restores vision and delays degeneration in the CNGB1(-/-) mouse model of retinitis pigmentosa.	CNGB1 CNGA1	1.90e-05	2	152	2	22802073
Pubmed	Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ERα in SUM-44 breast cancer cells and is associated with ERα over-expression in breast cancer.	ESR1 NSD3	1.90e-05	2	152	2	27005559
Pubmed	The loss of the BH3-only Bcl-2 family member Bid delays T-cell leukemogenesis in Atm-/- mice.	BID ATM	1.90e-05	2	152	2	23470523
Pubmed	The protein kinase from mitotic human cells that phosphorylates Ser-209 on the casein kinase II beta-subunit is p34cdc2.	CSNK2B CDK1	1.90e-05	2	152	2	7578274
Pubmed	Identification of plectin as a substrate of p34cdc2 kinase and mapping of a single phosphorylation site.	CDK1 PLEC	1.90e-05	2	152	2	8626512
Pubmed	Widespread aplasia cutis congenita in sibs with PLEC1 and ITGB4 variants.	ITGB4 PLEC	1.90e-05	2	152	2	31184804
Pubmed	Revisiting ankyrin-InsP3 receptor interactions: ankyrin-B associates with the cytoplasmic N-terminus of the InsP3 receptor.	ANK2 ITPR3	1.90e-05	2	152	2	18275062
Pubmed	Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.	CNGB1 CNGA1	1.90e-05	2	152	2	34699778
Pubmed	Involvement of Zizimin2/3 in the age-related defect of peritoneal B-1a cells as a source of anti-bacterial IgM.	DOCK11 DOCK10	1.90e-05	2	152	2	29099971
Pubmed	The analysis of estrogen receptor-α positive breast cancer stem-like cells unveils a high expression of the serpin proteinase inhibitor PI-9: Possible regulatory mechanisms.	ESR1 SERPINB9	1.90e-05	2	152	2	27121069
Pubmed	Cdk1-mediated DIAPH1 phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase.	DIAPH1 CDK1	1.90e-05	2	152	2	30816115
Pubmed	The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation.	DOCK11 DOCK10	1.90e-05	2	152	2	25729399
Pubmed	Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression.	SPIN2A SPIN2B	1.90e-05	2	152	2	12145692
Pubmed	KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function.	ESR1 KMT2C	1.90e-05	2	152	2	29755131
Pubmed	Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor.	ESR1 CSNK2B	1.90e-05	2	152	2	7838153
Pubmed	Oviductal estrogen receptor α signaling prevents protease-mediated embryo death.	AMHR2 ESR1	1.90e-05	2	152	2	26623518
Pubmed	Elevated expression of Erbin destabilizes ERα protein and promotes tumorigenesis in hepatocellular carcinoma.	ESR1 ERBIN	1.90e-05	2	152	2	28192186
Pubmed	The ATM-BID pathway plays a critical role in the DNA damage response by regulating mitochondria metabolism.	BID ATM	1.90e-05	2	152	2	26611459
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	NCKAP1 ARHGAP23 GIT1 ACTN4 ERBIN MYL12A PABPC3 KCTD3 OSBPL6 TMOD1	2.12e-05	430	152	10	32581705
Pubmed	Engagement of the G3BP2-TRIM25 Interaction by Nucleocapsid Protein Suppresses the Type I Interferon Response in SARS-CoV-2-Infected Cells.	CIP2A DHX8 DNAH12 ATM CNGB1	2.15e-05	76	152	5	36560452
Pubmed	Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain.	LAMB2 ITGB4 PLEC	2.27e-05	13	152	3	9670011
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CENPE DOCK11 KIF26B ROR1 OBSCN DNAH2 MYL12A KMT2C FREM2 DQX1 VPS13A CDK1 ATM	2.28e-05	736	152	13	29676528
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMG1 NCOA6 EMC1 RNF40 INPP5F RUFY3 KMT2C MTUS1 MED12L IPO13 ACAP3	2.29e-05	529	152	11	14621295
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	ANK2 GIT1 DOCK9 NAIP PSMD1 RIN1 SACS SLC4A10 PLEC	2.37e-05	347	152	9	17114649
Pubmed	Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation.	ESR1 NCAPH2 HECTD1	2.88e-05	14	152	3	26166704
Pubmed	Nonsyndromic Retinitis Pigmentosa Overview	SPATA7 EMC1 SEMA4A CNGB1 CNGA1	2.93e-05	81	152	5	20301590
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG1 MGAT4B EMC1 ATRX ARHGAP23 PPFIBP1 DOCK10 AP3B1 DDX3X FREM2 LIG4 CDK13	3.10e-05	650	152	12	38777146
Pubmed	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	NCOA6 NCKAP1 AHCTF1 DOCK10 MYOF KHDRBS1 OSBPL6 TOP3B	3.71e-05	283	152	8	18854154
Pubmed	Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip.	ABCC6 SEMA4A CNGB1 CNGA1 CNGA3	4.13e-05	87	152	5	20801516
Pubmed	Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects.	MAP3K12 CDK1 CAMSAP1	4.40e-05	16	152	3	36092713
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	SLC11A2 CARMIL2 ANK2 PPFIBP1 DOCK9 ROR1 RALGAPA2 ERBIN CNNM3 SH2D4A CAMSAP1	4.43e-05	569	152	11	30639242
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	NCKAP1 CIP2A ACTN4 ERBIN PIKFYVE MYOF NUP133	4.88e-05	216	152	7	31519766
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	SMG1 ATRX NCKAP1 ARHGAP23 PPFIBP1 MAP3K12 MYOF MYL9 CDK13 CSNK2B NUP133 CDK1 PLEC NQO2	4.94e-05	910	152	14	36736316
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	EMC1 NCKAP1 PPFIBP1 AGR2 ACTN4 URB2 DDX3X NSD3 MYOF MYL9 PREP CSNK2B MORF4L1 DIAPH1 CDK1 HECTD1 TOP3B	5.62e-05	1297	152	17	33545068
Pubmed	SMCHD1 promotes ATM-dependent DNA damage signaling and repair of uncapped telomeres.	TERF2 ATM	5.68e-05	3	152	2	32080884
Pubmed	Regulating ankyrin dynamics: Roles of sigma-1 receptors.	ANK2 ITPR3	5.68e-05	3	152	2	11149946
Pubmed	Mechanostress resistance involving formin homology proteins: G- and F-actin homeostasis-driven filament nucleation and helical polymerization-mediated actin polymer stabilization.	ACTN3 DIAPH1	5.68e-05	3	152	2	30309655
Pubmed	Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2.	TERF2 LIG4	5.68e-05	3	152	2	18451109
Interaction	CENPF interactions	CENPE TERF2 NUP133 PHLPP1 CDK1 NQO2 HECTD1 TOP3B	3.86e-06	122	151	8	int:CENPF
Interaction	PLEC interactions	ARHGAP23 ESR1 AHCTF1 ROR1 AGR2 URB2 ITGB4 ADH6 CS KHDRBS1 PHLPP1 CDK1 PLEC TOP3B	4.55e-06	430	151	14	int:PLEC
Interaction	YWHAB interactions	EMC1 CARMIL2 NCKAP1 ARHGAP23 CENPE DOCK11 KIF26B PPFIBP1 ESR1 DOCK9 AGR2 INPP5F ERBIN ITGB4 BID RIN1 VPS13D CS OSBPL6 DOT1L CAMSAP1 HECTD1	6.88e-06	1014	151	22	int:YWHAB
Interaction	YWHAH interactions	NCOA6 EMC1 CARMIL2 NCKAP1 GIT1 DOCK11 KIF26B PPFIBP1 ESR1 DOCK9 AGR2 INPP5F ERBIN DDX3X NSD3 RIN1 VPS13D MTUS1 OSBPL6 PLEC CAMSAP1 HECTD1 EDRF1	7.83e-06	1102	151	23	int:YWHAH
Interaction	GSK3A interactions	KIF26B PPFIBP1 CIP2A PSMD1 ACTN4 ERBIN DDX3X MYL12A VPS13D KHDRBS1 MTUS1 NUP133 CAMSAP1 HECTD1	1.08e-05	464	151	14	int:GSK3A
Interaction	RHOF interactions	EMC1 SLC11A2 NCKAP1 DOCK11 KIF26B PPFIBP1 DOCK9 AHCTF1 ACTN4 ERBIN PIKFYVE CNNM3 MYOF SH2D4A VPS13A DIAPH1 TOP3B	1.24e-05	673	151	17	int:RHOF
Interaction	RAC2 interactions	EMC1 SLC11A2 NCKAP1 GIT1 DOCK11 KIF26B PPFIBP1 DOCK9 PSMD1 ERBIN ARMCX3 ITPR3 CNNM3 MYOF USP5 VPS13D VPS13A	1.26e-05	674	151	17	int:RAC2
Interaction	DUX1 interactions	CENPE ACTN3 CSNK2B	1.41e-05	7	151	3	int:DUX1
Interaction	RAC1 interactions	DOCK3 EMC1 SLC11A2 CARMIL2 NCKAP1 ARHGAP23 GIT1 DOCK11 KIF26B PPFIBP1 ESR1 DOCK9 ERBIN PREX2 DDX3X PIKFYVE CNNM3 MYOF VPS13A DIAPH1 VAV2 PICK1	1.44e-05	1063	151	22	int:RAC1
Interaction	ERH interactions	ACP6 ESR1 AGR2 RNF40 TERF2 DHX8 CSNK2B OSBPL6 CDK1 DOT1L	1.64e-05	245	151	10	int:ERH
Interaction	WARS1 interactions	CCDC22 AGR2 LIG4 USP5 SH2D4A DIAPH1 TMOD1 PHLPP1 PLEC	1.81e-05	197	151	9	int:WARS1
Interaction	WRN interactions	ATRX ESR1 TERF2 DHX8 ATM HECTD1 TOP3B	1.93e-05	110	151	7	int:WRN
Interaction	CDK13 interactions	ESR1 TERF2 DHX8 CDK13 CDK1 HECTD1 TOP3B EDRF1	2.04e-05	153	151	8	int:CDK13
Interaction	HDAC4 interactions	ATRX ARHGAP23 DOCK11 CDIN1 ESR1 AGR2 ACTN4 RNF40 AP3B1 PREX2 KHDRBS1 KCTD3 OSBPL6 DIAPH1 ATM TOP3B PICK1	4.40e-05	744	151	17	int:HDAC4
Interaction	DSCAM interactions	ATRX ESR1 ACTN4 RUFY3 KHDRBS1 SACS CSNK2B PLEC	4.52e-05	171	151	8	int:DSCAM
Interaction	ORC1 interactions	ESR1 TERF2 CSNK2B CDK1 DOT1L TOP3B	4.60e-05	86	151	6	int:ORC1
Interaction	SMC4 interactions	TRAF3IP1 ESR1 PSMD1 NCAPH2 MYL12A LIG4 PHLPP1 PLEC DOT1L HECTD1	5.27e-05	281	151	10	int:SMC4
Interaction	YWHAG interactions	NCOA6 CARMIL2 NCKAP1 ARHGAP23 GIT1 DOCK11 KIF26B PPFIBP1 ESR1 DOCK9 AGR2 PSMD1 ACTN4 INPP5F ERBIN DDX3X RIN1 VPS13D MTUS1 OSBPL6 CAMSAP1 HECTD1 EDRF1	5.57e-05	1248	151	23	int:YWHAG
Interaction	FBXO22 interactions	NCKAP1 CENPE DOCK11 ESR1 DOCK9 OBSCN KMT2C VPS13D DNAH12 RNFT2 PHLPP1 ATM TOP3B HYDIN	5.70e-05	540	151	14	int:FBXO22
Interaction	RAC3 interactions	EMC1 SLC11A2 NCKAP1 GIT1 DOCK11 KIF26B PPFIBP1 ESR1 DOCK9 ERBIN ARMCX3 CNNM3 MYOF VPS13A DIAPH1	6.60e-05	619	151	15	int:RAC3
Interaction	KIFC1 interactions	NUSAP1 ESR1 MINDY3 PHLPP1 PLEC HECTD1	6.72e-05	92	151	6	int:KIFC1
Interaction	BUB1 interactions	CENPE KIF26B NCAPH2 AP3B1 TMOD1 CDK1 PLEC	7.87e-05	137	151	7	int:BUB1
Interaction	BLM interactions	ATRX ESR1 PSMD1 TERF2 DHX8 FAN1 CSNK2B ATM HECTD1	8.18e-05	239	151	9	int:BLM
Interaction	SFSWAP interactions	NCKAP1 ESR1 PSMD1 DHX8 DOT1L HECTD1	8.52e-05	96	151	6	int:SFSWAP
Interaction	MORC1 interactions	RNF40 DPH6 DHX8	8.63e-05	12	151	3	int:MORC1
Interaction	RAPGEF5 interactions	ANK2 ARHGAP23 PPFIBP1 RALGAPA2 PLEC	8.66e-05	60	151	5	int:RAPGEF5
Interaction	YWHAQ interactions	NCOA6 CARMIL2 NCKAP1 ARHGAP23 DOCK11 KIF26B PPFIBP1 ESR1 AGR2 PSMD1 INPP5F ERBIN MAP3K12 ITGB4 DDX3X VPS13D MTUS1 OSBPL6 PLEC CAMSAP1 HECTD1	9.30e-05	1118	151	21	int:YWHAQ
Interaction	LIMA1 interactions	NCKAP1 ESR1 PSMD1 ACTN4 ITPR3 KCTD3 OSBPL6 TMOD1 PHLPP1 PLEC DOT1L TOP3B	9.68e-05	429	151	12	int:LIMA1
Interaction	EIF6 interactions	ARHGAP23 GIT1 ESR1 AGR2 PSMD1 ITGB4 CSNK2B DOT1L HECTD1 TOP3B ACAP3	9.92e-05	365	151	11	int:EIF6
Interaction	RHOD interactions	EMC1 SLC11A2 NCKAP1 KIF26B PPFIBP1 ESR1 DOCK9 PSMD1 ERBIN ITPR3 CNNM3 MYOF VPS13A DIAPH1	1.05e-04	572	151	14	int:RHOD
Interaction	CHD8 interactions	ESR1 AGR2 NCAPH2 AP3B1 TERF2 NSD3 CSNK2B TOP3B	1.06e-04	193	151	8	int:CHD8
Interaction	MYOF interactions	EMC1 ESR1 AGR2 MYOF PHLPP1 TOP3B	1.19e-04	102	151	6	int:MYOF
Interaction	RAD9A interactions	ATRX CSNK2B CDK1 ATM TOP3B	1.37e-04	66	151	5	int:RAD9A
Interaction	NCAPG interactions	ESR1 PSMD1 NCAPH2 BID KHDRBS1 CDK1 PLEC HECTD1	1.45e-04	202	151	8	int:NCAPG
Interaction	IQGAP1 interactions	ESR1 AGR2 PSMD1 ACTN4 DDX3X CSNK2B KCTD3 DIAPH1 TMOD1 CDK1 PLEC PLEK HECTD1 TOP3B	1.48e-04	591	151	14	int:IQGAP1
Interaction	RHOG interactions	EMC1 SLC11A2 CARMIL2 GIT1 KIF26B PPFIBP1 DOCK9 RALGAPA2 ERBIN ARMCX3 PREX2 ITPR3 CNNM3 MYOF CS VPS13A DIAPH1 VAV2	1.63e-04	910	151	18	int:RHOG
Interaction	SMC2 interactions	TRAF3IP1 ATRX CENPE ESR1 PSMD1 NCAPH2 LIG4 PLEC DOT1L HECTD1	1.66e-04	323	151	10	int:SMC2
Cytoband	1q42.13	ZNF678 OBSCN URB2 NUP133	2.18e-05	49	152	4	1q42.13
Cytoband	Xp11.1	SPIN2A SPIN2B	6.51e-05	4	152	2	Xp11.1
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGAP23 DOCK11 DOCK9 DOCK10 PHLPP1 PLEK VAV2 PLEKHA8 ACAP3	3.72e-06	206	107	9	682
GeneFamily	Cyclic nucleotide gated channels	CNGB1 CNGA1 CNGA3	2.35e-05	10	107	3	250
GeneFamily	Actinins	ACTN4 ACTN3	2.07e-04	4	107	2	1112
GeneFamily	Tudor domain containing\|Spindlin family	SPIN2A SPIN2B	3.43e-04	5	107	2	1089
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	CENPE PREX2 ITPR3 SH2D4A SACS HYDIN	7.26e-04	181	107	6	694
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD3 KMT2C DOT1L	1.06e-03	34	107	3	487
GeneFamily	Myosin light chains\|EF-hand domain containing	MYL12A MYL9	3.01e-03	14	107	2	657
GeneFamily	DEAH-box helicases	DHX8 DHX32	3.94e-03	16	107	2	500
GeneFamily	Dyneins, axonemal	DNAH2 DNAH12	4.45e-03	17	107	2	536
Coexpression	GSE40493_BCL6_KO_VS_WT_TREG_UP	SMG1 NCOA6 AHCTF1 URB2 RALGAPA2 DPH6 VPS13D PHLPP1	9.02e-06	177	151	8	M9401
Coexpression	MURARO_PANCREAS_BETA_CELL	SLC11A2 ATRX NCKAP1 AHCTF1 ROR1 DOCK10 PSMD1 INPP5F AP3B1 TERF2 ARMCX3 RUFY3 ITPR3 PIKFYVE KMT2C SLC4A10 TMOD1 HECTD1	9.13e-06	946	151	18	M39169
Coexpression	GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN	MGAT4B ARHGAP23 KMT2C LIG4 PLEC NQO2 VAV2 ACAP3	1.02e-05	180	151	8	M8906
Coexpression	GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN	SMG1 DOCK10 INPP5F RALGAPA2 NSD3 CNNM3 KMT2C SERPINB9	2.03e-05	198	151	8	M8624
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	SLC11A2 ATRX NCKAP1 CENPE DOCK9 AHCTF1 ROR1 INPP5F AP3B1 PIKFYVE MYOF SACS CDK13 VPS13A NUP133 PHLPP1	3.67e-05	856	151	16	M4500
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MID_MESOTHELIAL_CELL	AMHR2 MGAT4B ARHGAP23 GIT1 DOCK11 DOCK9 ERBIN ITPR3 FREM2 SERPINB9 SH2D4A MTUS1 VPS13A RAB7B PLEC RABGGTA PICK1	3.81e-05	955	151	17	M45680
Coexpression	FAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON	PPFIBP1 DOCK9 SERPINB9 SLC4A10 PLEC HYDIN ACAP3	5.17e-05	166	151	7	M39026
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_LATE_MESOTHELIAL_CELL	AMHR2 MGAT4B ARHGAP23 GIT1 SPOCK1 DOCK11 ITPR3 SERPINB9 SH2D4A MTUS1 VPS13A RAB7B PLEC RABGGTA	5.97e-05	704	151	14	M45672
Coexpression	LAKE_ADULT_KIDNEY_C25_ENDOTHELIAL_CELLS_UNASSIGNED	PPFIBP1 DOCK9 RALGAPA2 MMRN1	6.71e-05	38	151	4	M39244
ToppCell	IPF-Endothelial\|IPF / Disease state, Lineage and Cell class	NCKAP1 ARHGAP23 PPFIBP1 DOCK9 HIF3A RALGAPA2 PREX2 MMRN1 ADGRF5	2.36e-08	194	152	9	9591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCell	Control-Endothelial\|Control / Disease state, Lineage and Cell class	NCKAP1 ARHGAP23 PPFIBP1 DOCK9 HIF3A RALGAPA2 PREX2 MMRN1 ADGRF5	2.36e-08	194	152	9	485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 ATRX ACTN4 ERBIN ITGB4 DDX3X FREM2 MORF4L1 PLEC	2.81e-08	198	152	9	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	COPD-Endothelial\|COPD / Disease state, Lineage and Cell class	ARHGAP23 PPFIBP1 DOCK9 HIF3A RALGAPA2 PREX2 MMRN1 ADGRF5	3.43e-07	193	152	8	093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF26B PPFIBP1 DOCK9 HIF3A RALGAPA2 MMRN1 MTUS1 ADGRF5	3.43e-07	193	152	8	bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCell	Cerebellum-Endothelial\|Cerebellum / BrainAtlas - Mouse McCarroll V32	PPFIBP1 LAMB2 ACTN4 MYL12A MYOF SERPINB9 MYL9 ADGRF5	3.71e-07	195	152	8	2192fd9b4682054776f0716933aed5a4a9412657
ToppCell	severe-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NUSAP1 NCKAP1 CENPE DOCK9 NCAPH2 RALGAPA2 KMT2C MED12L	4.01e-07	197	152	8	70704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell	5'-Adult-Appendix-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGAP23 PPFIBP1 DOCK9 RALGAPA2 PREX2 MMRN1 MTUS1 ADGRF5	4.16e-07	198	152	8	90e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 ARHGAP23 DOCK10 ERBIN ITGB4 IPO13 TMOD1 PHLPP1	4.49e-07	200	152	8	0e85c90719d9ec51a566e230c9dd2909d8df1f52
ToppCell	Parenchymal-10x5prime-Endothelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP23 PPFIBP1 DOCK9 HIF3A RALGAPA2 PREX2 MMRN1 ADGRF5	4.49e-07	200	152	8	0e648e9eb96c83a94505d07323785a7a40997eb0
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGAP23 GIT1 PPFIBP1 DOCK9 ITGB4 MMRN1 SERPINB9	3.23e-06	183	152	7	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 ATRX DOCK10 ERBIN DDX3X DIAPH1 RAB7B	3.35e-06	184	152	7	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PPFIBP1 DOCK9 HIF3A GRM8 PREX2 KCTD3 ADGRF5	4.00e-06	189	152	7	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	PND10-Epithelial-Epithelial_Airway\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAF3IP1 DNAH12 MTUS1 OSBPL6 HYDIN RSPH10B LRRC23	4.00e-06	189	152	7	407d8a59969d83f014600aae1a55092283a13970
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PPFIBP1 DOCK9 OBSCN HIF3A PREX2 PHLPP1 ADGRF5	4.14e-06	190	152	7	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HIF3A ABCC6 ITPR3 FREM2 MTUS1 ADGRF5 LRRC23	4.43e-06	192	152	7	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FREM2 DNAH12 MTUS1 OSBPL6 ADGRF5 HYDIN LRRC23	4.59e-06	193	152	7	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	IPF-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	NCKAP1 PPFIBP1 DOCK9 HIF3A RALGAPA2 PREX2 MMRN1	4.59e-06	193	152	7	ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	C1orf87 AGR2 DNAH2 OSBPL6 HYDIN RSPH10B LRRC23	4.91e-06	195	152	7	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP23 PPFIBP1 DOCK9 HIF3A RALGAPA2 PREX2 ADGRF5	5.07e-06	196	152	7	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP23 PPFIBP1 DOCK9 HIF3A RALGAPA2 PREX2 ADGRF5	5.07e-06	196	152	7	4cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK11 KIF26B DOCK10 PREX2 MTUS1 GRIN3A VAV2	5.07e-06	196	152	7	7af6c5147ac859353504d19727dbe24f63a29dd4
ToppCell	wk_20-22-Epithelial-Proximal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	C1orf87 AGR2 DNAH2 DNAH12 OSBPL6 HYDIN LRRC23	5.42e-06	198	152	7	16c54b884500066ade05a406915f9569ca8abdfc
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP23 DOCK9 HIF3A ITGB4 MTUS1 ADGRF5 PLEC	5.61e-06	199	152	7	a3ec743b978ba8fdf1677b4971b5731f50ddd30f
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP23 DOCK10 ERBIN ITGB4 KCTD3 IPO13 TMOD1	5.61e-06	199	152	7	67d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NCKAP1 PPFIBP1 DOCK9 ITGB4 MMRN1 MTUS1 ADGRF5	5.61e-06	199	152	7	97052c28e354833901f28d339b09f97f50a5b752
ToppCell	ASK452-Endothelial\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	ARHGAP23 PPFIBP1 DOCK9 RALGAPA2 PREX2 MMRN1 ADGRF5	5.61e-06	199	152	7	0bc97a9a78aaafd1554ae6a61356ed9ea4983fa5
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	ATRX SPOCK1 PPFIBP1 AGR2 NSD3 MYL9 KHDRBS1	5.61e-06	199	152	7	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	Neuronal-Inhibitory\|Neuronal / cells hierarchy compared to all cells using T-Statistic	DOCK11 KIF26B DOCK10 PREX2 MTUS1 GRIN3A VAV2	5.79e-06	200	152	7	9ff8647e2de0b538e15929dca88ebb20ff7ab043
ToppCell	Bronchial-10x5prime-Endothelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PPFIBP1 DOCK9 HIF3A RALGAPA2 PREX2 MMRN1 ADGRF5	5.79e-06	200	152	7	ad34c978cc6b89b4c1c8c9b2fb2a938051b555a0
ToppCell	5'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGAP23 PPFIBP1 DOCK9 PREX2 MMRN1 MTUS1 ADGRF5	5.79e-06	200	152	7	2554b77edfe3d378296b0b25625caacbfb1c0e76
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BID SERPINB9 CSNK2B MED12L RAB7B PLEK	1.55e-05	155	152	6	9f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NUSAP1 CENPE CIP2A MINPP1 PREX2 RIN1	2.07e-05	163	152	6	7864e966c228282b4b63c43164dba3faba21026d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK9 AHCTF1 DOCK10 SACS VPS13A TTC21B	2.37e-05	167	152	6	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMPRSS13 SPOCK1 DOCK11 KIF26B PPFIBP1 PREX2	2.62e-05	170	152	6	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MGAT4B PPFIBP1 DOCK9 ITGB4 MMRN1 PLEC	2.71e-05	171	152	6	686f95892c3909973c66c9a27159a070a068f175
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MGAT4B PPFIBP1 DOCK9 ITGB4 MMRN1 PLEC	2.71e-05	171	152	6	f7ba03e7bdb687f93782c936c7b3374cc5b3b77c
ToppCell	PND14-Endothelial-Endothelial_lymphatic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MGAT4B PPFIBP1 DOCK9 ITGB4 MMRN1 PLEC	2.71e-05	171	152	6	d0ac50071a3854d02113c455fcc940a6ec59bbb9
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MGAT4B PPFIBP1 DOCK9 ITGB4 MMRN1 PLEC	2.71e-05	171	152	6	fbf8e9db00573adcada4b25730e191417b7c9999
ToppCell	PND14-Immune-Immune_Myeloid-DC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NUSAP1 CENPE DOCK10 RAB7B SEMA4A PLEK	2.71e-05	171	152	6	8772d6349db24de47f089df2032a80345db7177f
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C1orf87 DNAH2 DNAH12 OSBPL6 HYDIN LRRC23	2.89e-05	173	152	6	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 CENPE CDIN1 CIP2A SERPINB9 CDK1	2.89e-05	173	152	6	31784679190fbd95fc23d7c66008eb21b8c7cc5d
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NUSAP1 MGAT4B CENPE NUP133 CDK1 PLEK	2.98e-05	174	152	6	65147b0f8c2ccadd5685430d31081520c157536a
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 ANK2 CDIN1 ROR1 OBSCN MYL12A	3.18e-05	176	152	6	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	ASK452-Endothelial-Lymphatic\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	PPFIBP1 CIP2A MMRN1 MTUS1 IPO13 TMOD1	3.18e-05	176	152	6	b4d280ecc07701d526f50d44c45ea91b3eeb00b1
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF26B PPFIBP1 LAMB2 MMRN1 SPIN2B RSPH10B	3.18e-05	176	152	6	5d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP23 PPFIBP1 DOCK9 ITGB4 MMRN1 MTUS1	3.28e-05	177	152	6	227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP23 PPFIBP1 DOCK9 ITGB4 MMRN1 MTUS1	3.28e-05	177	152	6	66ffa279147961080c104242a08b176e301d80e3
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP23 PPFIBP1 DOCK9 ITGB4 MMRN1 MTUS1	3.28e-05	177	152	6	0cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPFIBP1 DOCK9 HIF3A MMRN1 MTUS1 TMOD1	3.50e-05	179	152	6	40c65e8623547aeb80f9cd2366e29072467ce069
ToppCell	390C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CARMIL2 ZNF678 MINDY3 VPS13A TTC21B TOP3B	3.50e-05	179	152	6	3edcd1356e49b1f5514c585861999e079ca5e579
ToppCell	390C-Lymphocytic-ILC-ILC-1\|390C / Donor, Lineage, Cell class and subclass (all cells)	CARMIL2 ZNF678 MINDY3 VPS13A TTC21B TOP3B	3.50e-05	179	152	6	e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NUSAP1 CENPE CIP2A DNAH2 MINPP1 CDK1	3.72e-05	181	152	6	c35ca98c474e31917e0a53c092397e0d8d18b37c
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 ANK2 CDIN1 ROR1 OBSCN TMOD1	3.72e-05	181	152	6	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	NUSAP1 CENPE CIP2A DNAH2 CDK1 PLEC	3.72e-05	181	152	6	ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating-Lymphatic_EC_proliferating_L.2.5.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUSAP1 CENPE PPFIBP1 MMRN1 TMOD1 CDK1	3.84e-05	182	152	6	f703963b5d1e8c1f95d78807521048553b0792d8
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NUSAP1 CENPE MYOF CDK1 SEMA4A PLEK	3.84e-05	182	152	6	21dcab170ffeef89faa9fee5008568cb6e15c694
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 NCKAP1 CENPE CIP2A SH2D4A CDK1	3.84e-05	182	152	6	39f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCell	wk_08-11-Mesenchymal-Mesothelial-Late_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	AMHR2 GIT1 SPOCK1 SERPINB9 OSBPL6 ACAP3	3.84e-05	182	152	6	f8257c884393f168f605d371e0840cfca8d3657e
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 ATRX DOCK10 ERBIN DIAPH1 RAB7B	3.84e-05	182	152	6	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK3 ANK2 SPOCK1 MED12L TMOD1 CNGB1	3.84e-05	182	152	6	be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUSAP1 CENPE PPFIBP1 MMRN1 TMOD1 CDK1	3.84e-05	182	152	6	ebd177ad5eac51bf2db0657596618bdf1e5d46e1
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCKAP1 ARHGAP23 RALGAPA2 PREX2 MTUS1 ADGRF5	3.95e-05	183	152	6	709a486154b3157427deb3b8886b63ac39ea42dd
ToppCell	droplet-Liver-nan-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCKAP1 ARHGAP23 RALGAPA2 PREX2 MTUS1 ADGRF5	3.95e-05	183	152	6	dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPFIBP1 HIF3A RALGAPA2 MMRN1 OSBPL6 TMOD1	3.95e-05	183	152	6	2d0d3b486498a7903fa9a1f48b189291da49c430
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC11A2 KIF26B PSMD1 FAN1 CDK1 PLEKHA8	3.95e-05	183	152	6	3ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCell	Control-APC-like-Dendritic_cells\|Control / group, cell type (main and fine annotations)	DOCK10 BID SERPINB9 MED12L RAB7B PLEK	3.95e-05	183	152	6	8f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCell	Control-APC-like\|Control / group, cell type (main and fine annotations)	DOCK10 BID SERPINB9 MED12L RAB7B PLEK	3.95e-05	183	152	6	c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK3 ANK2 CDIN1 ROR1 OBSCN TMOD1	4.08e-05	184	152	6	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 ATRX DOCK10 ERBIN DIAPH1 RAB7B	4.20e-05	185	152	6	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ANK2 PPFIBP1 CDIN1 ROR1 OBSCN MYL12A	4.20e-05	185	152	6	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	droplet-Bladder-BLADDER-1m-Hematologic-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPATA7 DOCK11 CIP2A DOCK10 SPIN2A CDK1	4.20e-05	185	152	6	969248b63d4ce335f223528de756bcddffadbd77
ToppCell	Mild_COVID-19-Epithelial-AT1/AT2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ANK2 TMPRSS13 KIF26B HIF3A FREM2 ADGRF5	4.20e-05	185	152	6	c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCell	Control-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	NCKAP1 PPFIBP1 DOCK9 HIF3A PREX2 ADGRF5	4.20e-05	185	152	6	a28187c2fd23564314b35759479ff2ca21f61485
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ROR1 DOCK10 PREX2 FREM2 GRIN3A VAV2	4.33e-05	186	152	6	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|bone_marrow / Manually curated celltypes from each tissue	NUSAP1 CENPE NAIP CDK1 SEMA4A PLEC	4.33e-05	186	152	6	e82d5e7a976b9cfa2b4640c7a7cd1cfea19c4806
ToppCell	PND14-Epithelial-Epithelial_Airway\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAF3IP1 DNAH12 OSBPL6 HYDIN RSPH10B LRRC23	4.46e-05	187	152	6	1399c703505211c510b3f14c7a2aa9930566c473
ToppCell	PND28-Epithelial-Epithelial_Airway\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAF3IP1 DNAH12 MTUS1 OSBPL6 RSPH10B LRRC23	4.46e-05	187	152	6	f777dd5eb5ccd554ebe1ed60a738b5dd45e18bb9
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HIF3A ITPR3 FREM2 MTUS1 ADGRF5 LRRC23	4.46e-05	187	152	6	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	DOCK9 HIF3A RALGAPA2 ITGB4 PREX2 MMRN1	4.46e-05	187	152	6	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	Control-Endothelial-VE_Capillary_A\|Control / Disease state, Lineage and Cell class	NCKAP1 PPFIBP1 DOCK9 HIF3A PREX2 ADGRF5	4.46e-05	187	152	6	54d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell	21-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	C1orf87 DNAH2 DNAH12 OSBPL6 HYDIN LRRC23	4.60e-05	188	152	6	803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	INPP5F BID SERPINB9 MED12L RAB7B PLEK	4.60e-05	188	152	6	d5ce3ffe783c322b4765b790e861727e46bc34b3
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAF3IP1 DNAH2 DNAH12 HYDIN RSPH10B LRRC23	4.73e-05	189	152	6	b55de812043b670cbde810d7d42f45909b6d66ef
ToppCell	Substantia_nigra-Endothelial\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	LAMB2 ACTN4 MYL12A MYOF SERPINB9 MYL9	4.73e-05	189	152	6	bef8234bd9c4d6e3cdef0791d8066b39ba56ebba
ToppCell	Control-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	ARHGAP23 PPFIBP1 DOCK9 RALGAPA2 PREX2 MMRN1	4.73e-05	189	152	6	c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	DOCK9 RUFY3 ITPR3 FREM2 MTUS1 ADGRF5	4.73e-05	189	152	6	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAF3IP1 DNAH12 OSBPL6 HYDIN RSPH10B LRRC23	4.73e-05	189	152	6	02c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAF3IP1 DNAH12 OSBPL6 HYDIN RSPH10B LRRC23	4.73e-05	189	152	6	164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCell	Control-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	ARHGAP23 PPFIBP1 HIF3A RALGAPA2 PREX2 MMRN1	4.73e-05	189	152	6	f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK9 RALGAPA2 ITGB4 MMRN1 MTUS1 TMOD1	4.73e-05	189	152	6	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	Epithelial-D_(Ciliated)\|World / shred on cell class and cell subclass (v4)	TRAF3IP1 DNAH12 OSBPL6 HYDIN RSPH10B LRRC23	4.73e-05	189	152	6	0bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAF3IP1 DNAH12 OSBPL6 HYDIN RSPH10B LRRC23	4.73e-05	189	152	6	a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ANK2 CDIN1 ROR1 OBSCN ACTN4 DIAPH1	4.73e-05	189	152	6	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAF3IP1 DNAH2 DNAH12 HYDIN RSPH10B LRRC23	4.73e-05	189	152	6	4e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK9 HIF3A RALGAPA2 MMRN1 MTUS1 TMOD1	4.87e-05	190	152	6	876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	ANK2 CDIN1 ROR1 OBSCN ACTN4 DIAPH1	4.87e-05	190	152	6	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAF3IP1 DNAH12 OSBPL6 HYDIN RSPH10B LRRC23	4.87e-05	190	152	6	088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRAF3IP1 DNAH12 OSBPL6 HYDIN RSPH10B LRRC23	4.87e-05	190	152	6	35248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK9 HIF3A RALGAPA2 MMRN1 MTUS1 TMOD1	4.87e-05	190	152	6	be9f36127028f52ca5fc1b32ba15a6c26aad69ac
Drug	Isopyrin hydrochloride [18342-39-7]; Down 200; 14.2uM; PC3; HT_HG-U133A	SPATA7 SLC11A2 TRAF3IP1 ATRX NCAPH2 MAP3K12 RUFY3 ITPR3 PREP VPS13A NQO2 COQ7	9.24e-09	199	151	12	5879_DN
Drug	Terfenadine [50679-08-8]; Down 200; 8.4uM; MCF7; HT_HG-U133A	TRAF3IP1 ESR1 NCAPH2 URB2 VPS13D VPS13A ATM PLEC CAMSAP1 EDRF1	6.14e-07	191	151	10	2227_DN
Drug	Chloramphenicol [56-75-7]; Down 200; 12.4uM; PC3; HT_HG-U133A	SERHL2 CCDC22 TRAF3IP1 ESR1 MAP3K12 MYOF VPS13D ZNF667 TBX10 LRRC23	7.08e-07	194	151	10	5047_DN
Drug	2-propylpentanoic acid; Down 200; 50uM; HL60; HT_HG-U133A	ATRX GIT1 NCAPH2 AP3B1 GRM8 NSD3 ITPR3 MYOF EDRF1 LRRC23	8.93e-07	199	151	10	2682_DN
Drug	PF-00562151-00 [351320-12-2]; Down 200; 10uM; PC3; HT_HG-U133A	SERHL2 DOCK9 DOCK10 NCAPH2 ITGB4 NSD3 PLEC PICK1 LRRC23	5.63e-06	192	151	9	5959_DN
Drug	semustine; Down 200; 100uM; PC3; HT_HG-U133A	SPATA7 TRAF3IP1 GIT1 ESR1 ROR1 AP3B1 VPS13D ZNF667 VAV2	6.13e-06	194	151	9	7492_DN
Drug	Benzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; MCF7; HT_HG-U133A	SERHL2 PPFIBP1 ESR1 GRM8 ITGB4 RIN1 MYOF CDK13 TMOD1	6.39e-06	195	151	9	7359_UP
Drug	Furazolidone [67-45-8]; Down 200; 17.8uM; MCF7; HT_HG-U133A	EMC1 ESR1 NCAPH2 RUFY3 NSD3 VPS13D RNFT2 TOP3B EDRF1	6.39e-06	195	151	9	3358_DN
Drug	Benfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A	ESR1 MYOF VPS13D CDK13 ADGRF5 CAMSAP1 EDRF1 VAV2 PICK1	6.66e-06	196	151	9	3837_UP
Drug	Nafcillin sodium salt monohydrate [7177-50-6]; Down 200; 8.8uM; PC3; HT_HG-U133A	SERHL2 GIT1 ROR1 NSD3 RIN1 MYL9 MTUS1 EDRF1 RABGGTA	6.93e-06	197	151	9	3983_DN
Drug	Amidopyrine [58-15-1]; Down 200; 17.2uM; MCF7; HT_HG-U133A	EMC1 TRAF3IP1 NCAPH2 USP5 RNFT2 TBX10 CAMSAP1 PICK1 LRRC23	6.93e-06	197	151	9	2222_DN
Drug	Ioversol [87771-40-2]; Down 200; 5uM; MCF7; HT_HG-U133A	NCAPH2 MAP3K12 RUFY3 NSD3 RIN1 VPS13D SERPINB9 TMOD1 TOP3B	6.93e-06	197	151	9	3365_DN
Drug	Betahistine mesylate [54856-23-4]; Down 200; 17.2uM; PC3; HT_HG-U133A	CCDC22 EMC1 TRAF3IP1 GIT1 ESR1 NSD3 VPS13D MTUS1 LRRC23	6.93e-06	197	151	9	6611_DN
Drug	H-89, Dihydrochloride; Down 200; 0.5uM; MCF7; HT_HG-U133A	CCDC22 EMC1 NCAPH2 RUFY3 NSD3 RIN1 MINDY3 TMOD1 LRRC23	7.22e-06	198	151	9	6878_DN
Drug	Oxybenzone [131-57-7]; Up 200; 17.6uM; MCF7; HT_HG-U133A	SPOCK1 ESR1 RUFY3 MINDY3 VPS13D CDK13 PLEC CNGB1 EDRF1	7.52e-06	199	151	9	6469_UP
Drug	Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; MCF7; HT_HG-U133A	TRAF3IP1 NCAPH2 PREX2 MYOF DIAPH1 TMOD1 TBX10 ATM COQ7	7.52e-06	199	151	9	2237_DN
Drug	Etifenin [63245-28-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A	GIT1 ESR1 RUFY3 NSD3 VPS13A SEMA4A PLEC TOP3B VAV2	7.84e-06	200	151	9	2838_DN
Drug	ICRF-193	LIG4 CDK13 CDK1 ATM TOP3B	2.92e-05	54	151	5	CID000115150
Drug	17-AAG; Up 200; 1uM; PC3; HT_HG-U133A	SERHL2 GIT1 ESR1 AGR2 NCAPH2 BID RIN1 EDRF1	3.37e-05	185	151	8	1226_UP
Drug	Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A	ESR1 DOCK10 NCAPH2 RUFY3 DDX3X MINDY3 MYOF CAMSAP1	4.08e-05	190	151	8	3927_DN
Drug	Naproxen [22204-53-1]; Down 200; 17.4uM; MCF7; HT_HG-U133A	CCDC22 ESR1 ITGB4 NSD3 DIAPH1 TMOD1 ATM EDRF1	4.23e-05	191	151	8	1706_DN
Drug	Beta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A	ATRX NCAPH2 RIN1 MINDY3 MYOF TMOD1 PLEC COQ7	4.23e-05	191	151	8	3890_DN
Drug	lithium indium	SPIN2A SPIN2B	4.37e-05	2	151	2	CID011116062
Drug	scandium phosphate	SPIN2A SPIN2B	4.37e-05	2	151	2	CID006365269
Drug	rubidium nitrate	SPIN2A SPIN2B	4.37e-05	2	151	2	CID000025731
Drug	Hydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; HL60; HT_HG-U133A	CCDC22 EMC1 DOCK10 MAP3K12 NSD3 VPS13D SH2D4A ATM	4.72e-05	194	151	8	2430_DN
Drug	Bufexamac [2438-72-4]; Up 200; 18uM; MCF7; HT_HG-U133A	SLC11A2 TRAF3IP1 MAP3K12 RUFY3 LIG4 SERPINB9 TBX10 COQ7	4.72e-05	194	151	8	7413_UP
Drug	Hydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; PC3; HT_HG-U133A	EMC1 TRAF3IP1 GIT1 ROR1 GRM8 ITPR3 TBX10 LRRC23	4.72e-05	194	151	8	6660_DN
Drug	ICI 182,780; Down 200; 0.01uM; HL60; HT_HG-U133A	SPATA7 PPFIBP1 NCAPH2 MAP3K12 RUFY3 MTUS1 PLEC EDRF1	4.72e-05	194	151	8	1179_DN
Drug	Metaraminol bitartrate [33402-03-8]; Down 200; 8.6uM; MCF7; HT_HG-U133A	ESR1 GRM8 DDX3X RIN1 VPS13D ATM SEMA4A EDRF1	4.90e-05	195	151	8	4692_DN
Drug	Metyrapone [54-36-4]; Down 200; 17.6uM; MCF7; HT_HG-U133A	SLC11A2 NCAPH2 MAP3K12 NSD3 MYOF USP5 TMOD1 SEMA4A	5.08e-05	196	151	8	6447_DN
Drug	Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; MCF7; HT_HG-U133A	EMC1 ESR1 MAP3K12 ITGB4 NSD3 SH2D4A PLEC PICK1	5.08e-05	196	151	8	3435_UP
Drug	Carbachol [51-83-2]; Up 200; 21.8uM; HL60; HT_HG-U133A	SPOCK1 KIF26B LAMB2 ITGB4 MTUS1 RNFT2 TMOD1 VAV2	5.08e-05	196	151	8	3042_UP
Drug	Piretanide [55837-27-9]; Up 200; 11uM; PC3; HT_HG-U133A	SERHL2 ESR1 ITGB4 MTUS1 CDK13 ATM SEMA4A TOP3B	5.08e-05	196	151	8	4490_UP
Drug	Terazosin hydrochloride [63590-64-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A	SPATA7 GIT1 NCAPH2 RUFY3 NSD3 MYOF SH2D4A PLEC	5.08e-05	196	151	8	7187_DN
Drug	Natamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A	SLC11A2 TRAF3IP1 DOCK9 RIN1 SERPINB9 ADGRF5 ATM EDRF1	5.08e-05	196	151	8	7167_UP
Drug	ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A	TRAF3IP1 ESR1 ROR1 ITGB4 DDX3X ITPR3 VPS13D TOP3B	5.08e-05	196	151	8	7495_DN
Drug	beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; MCF7; HT_HG-U133A	GIT1 ESR1 PREX2 VPS13A PHLPP1 ATM VAV2 COQ7	5.08e-05	196	151	8	4984_DN
Drug	Leflunomide [75706-12-6]; Down 200; 14.8uM; PC3; HT_HG-U133A	CCDC22 SLC11A2 ATRX MAP3K12 RUFY3 NSD3 VPS13D COQ7	5.26e-05	197	151	8	5884_DN
Drug	Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	EMC1 MAP3K12 ITPR3 MINDY3 MYOF VPS13D ATM SEMA4A	5.26e-05	197	151	8	2821_UP
Drug	Ethamivan [304-84-7]; Up 200; 18uM; PC3; HT_HG-U133A	SLC11A2 TRAF3IP1 PPFIBP1 LIG4 VPS13D MTUS1 VPS13A LRRC23	5.26e-05	197	151	8	7260_UP
Drug	Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A	GIT1 NCAPH2 MINDY3 MYOF USP5 RNFT2 ATM PLEC	5.26e-05	197	151	8	7201_DN
Drug	Nabumetone [42924-53-8]; Down 200; 17.6uM; MCF7; HT_HG-U133A	ESR1 NCAPH2 MAP3K12 MYOF SH2D4A RNFT2 TMOD1 COQ7	5.26e-05	197	151	8	6487_DN
Drug	Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	SERHL2 EMC1 PPFIBP1 MAP3K12 RUFY3 CDK13 TMOD1 CAMSAP1	5.26e-05	197	151	8	3399_DN
Drug	Oxamniquine [21738-42-1]; Up 200; 14.4uM; MCF7; HT_HG-U133A	EMC1 ESR1 DOCK10 NCAPH2 NSD3 MYOF VPS13D CDK13	5.26e-05	197	151	8	7344_UP
Drug	Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; MCF7; HT_HG-U133A	GIT1 ESR1 LAMB2 NCAPH2 CDK13 TMOD1 PLEC LRRC23	5.26e-05	197	151	8	3456_DN
Drug	2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A	ESR1 DDX3X MINDY3 MYOF USP5 VPS13D SH2D4A CDK13	5.26e-05	197	151	8	6999_DN
Drug	Paromomycin sulfate [1263-89-4]; Down 200; 5.6uM; MCF7; HT_HG-U133A	SERHL2 CCDC22 EMC1 ESR1 PREX2 NSD3 LIG4 EDRF1	5.46e-05	198	151	8	3356_DN
Drug	Cefaclor [70356-03-5]; Down 200; 10.4uM; PC3; HT_HG-U133A	EMC1 ESR1 DOCK9 NCAPH2 GRM8 CDK13 ZNF667 LRRC23	5.46e-05	198	151	8	6622_DN
Drug	U-62066 [87151-85-7]; Down 200; 1uM; MCF7; HT_HG-U133A	SLC11A2 PPFIBP1 GRM8 RUFY3 MYOF CDK13 PICK1 LRRC23	5.46e-05	198	151	8	3901_DN
Drug	Ifosfamide [3778-73-2]; Down 200; 15.4uM; MCF7; HT_HG-U133A	EMC1 GIT1 NCAPH2 RUFY3 DIAPH1 TMOD1 SEMA4A LRRC23	5.65e-05	199	151	8	3485_DN
Drug	Isocarboxazid [59-63-2]; Down 200; 17.2uM; PC3; HT_HG-U133A	ROR1 NCAPH2 MAP3K12 ITGB4 PREX2 ZNF667 EDRF1 LRRC23	5.65e-05	199	151	8	3684_DN
Drug	Bromopride [4093-35-0]; Down 200; 11.6uM; PC3; HT_HG-U133A	ROR1 DOCK10 NCAPH2 RUFY3 NSD3 CDK13 ZNF667 LRRC23	5.65e-05	199	151	8	4278_DN
Drug	Fluorometholone [426-13-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A	SERHL2 PREX2 SH2D4A VPS13A PHLPP1 ATM COQ7 PICK1	5.86e-05	200	151	8	6071_DN
Drug	alpha-estradiol; Down 200; 0.01uM; HL60; HT_HG-U133A	MAP3K12 RUFY3 RIN1 MYOF USP5 KHDRBS1 TMOD1 EDRF1	5.86e-05	200	151	8	2670_DN
Drug	Repaglinide [135062-02-1]; Down 200; 8.8uM; PC3; HT_HG-U133A	SPATA7 CCDC22 NCAPH2 AP3B1 RUFY3 ITPR3 MYOF VPS13D	5.86e-05	200	151	8	5862_DN
Drug	AC1NSVQS	MYL12A MYL9 PLEK	6.02e-05	12	151	3	CID005317517
Drug	torachrysone	ESR1 PREP	1.31e-04	3	151	2	CID005321977
Drug	raloxifene core	NCOA6 ESR1	1.31e-04	3	151	2	CID000445920
Drug	beta Carotene	ANK2 NCKAP1 CENPE ESR1 ITGB4 TTC21B COQ7	1.71e-04	175	151	7	ctd:D019207
Drug	dichlorobenzamil	PLEK CNGB1 CNGA1	1.82e-04	17	151	3	CID000114771
Drug	resveratrol; Down 200; 10uM; MCF7; HT_HG-U133A_EA	CCDC22 CENPE ESR1 URB2 MTUS1 CDK1 SEMA4A	1.84e-04	177	151	7	841_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ESR1 NCAPH2 RUFY3 MYOF SH2D4A SEMA4A COQ7	2.04e-04	180	151	7	6454_DN
Drug	Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; MCF7; HT_HG-U133A	ESR1 RUFY3 DDX3X NSD3 ATM COQ7 LRRC23	2.41e-04	185	151	7	4688_DN
Drug	diphenylketen	SPIN2A SPIN2B	2.60e-04	4	151	2	CID000013696
Drug	17-AAG; Down 200; 1uM; PC3; HT_HG-U133A	SERHL2 SLC11A2 AP3B1 ITGB4 NSD3 MINDY3 PICK1	2.66e-04	188	151	7	5958_DN
Drug	Muramic acid, N-acetyl [10597-89-4]; Down 200; 13.6uM; MCF7; HT_HG-U133A	ESR1 NCAPH2 DDX3X VPS13D CDK13 ATM PLEC	2.74e-04	189	151	7	3262_DN
Drug	GSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT_HG-U133A	SLC11A2 ROR1 DOCK10 NSD3 MTUS1 CDK13 EDRF1	2.83e-04	190	151	7	7070_UP
Drug	radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A	ESR1 NCAPH2 PREX2 VPS13D SEMA4A COQ7 LRRC23	2.83e-04	190	151	7	6979_UP
Drug	Denatonium benzoate [3734-33-6]; Down 200; 9uM; HL60; HT_HG-U133A	EMC1 VPS13D MTUS1 VPS13A PLEC CAMSAP1 COQ7	2.92e-04	191	151	7	3123_DN
Drug	Homochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; MCF7; HT_HG-U133A	NCAPH2 MAP3K12 ITGB4 MYOF RNFT2 ADGRF5 COQ7	2.92e-04	191	151	7	7417_UP
Drug	Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; MCF7; HT_HG-U133A	ESR1 PREX2 RUFY3 DDX3X NSD3 MINDY3 ATM	2.92e-04	191	151	7	2824_UP
Drug	Nitrofural [59-87-0]; Down 200; 20.2uM; PC3; HT_HG-U133A	ITGB4 DDX3X ITPR3 MTUS1 ZNF667 PLEC LRRC23	2.92e-04	191	151	7	6721_DN
Drug	Labetalol hydrochloride [32780-64-6]; Down 200; 11uM; MCF7; HT_HG-U133A	EMC1 TRAF3IP1 ESR1 NCAPH2 RUFY3 MYOF ATM	3.02e-04	192	151	7	6809_DN
Drug	pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A	SERHL2 DOCK10 AP3B1 VPS13D CDK13 TBX10 LRRC23	3.02e-04	192	151	7	5930_DN
Drug	Resveratrol [501-36-0]; Down 200; 17.6uM; MCF7; HT_HG-U133A	SPATA7 CENPE ESR1 AP3B1 RUFY3 NSD3 USP5	3.02e-04	192	151	7	5509_DN
Drug	Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A	TRAF3IP1 ATRX ESR1 NCAPH2 RUFY3 VPS13D ATM	3.02e-04	192	151	7	4746_DN
Drug	Cyanocobalamin [68-19-9]; Down 200; 3uM; MCF7; HT_HG-U133A	NCAPH2 MINDY3 USP5 VPS13D SERPINB9 MTUS1 ATM	3.02e-04	192	151	7	3252_DN
Drug	Piretanide [55837-27-9]; Up 200; 11uM; HL60; HT_HG-U133A	ACP6 SPOCK1 ESR1 LAMB2 GRM8 TMOD1 PICK1	3.02e-04	192	151	7	6144_UP
Drug	Furosemide [54-31-9]; Down 200; 12uM; MCF7; HT_HG-U133A	CCDC22 ESR1 DOCK9 ITGB4 RUFY3 RNFT2 TMOD1	3.11e-04	193	151	7	3197_DN
Drug	0316684-0000 [391209-55-5]; Down 200; 10uM; MCF7; HT_HG-U133A	ATRX PPFIBP1 ESR1 ITGB4 DDX3X LIG4 PLEC	3.11e-04	193	151	7	7052_DN
Drug	0316684-0000 [391209-55-5]; Up 200; 10uM; PC3; HT_HG-U133A	SERHL2 TRAF3IP1 MAP3K12 MINDY3 USP5 VPS13D MTUS1	3.11e-04	193	151	7	7057_UP
Drug	Iohexol [66108-95-0]; Down 200; 4.8uM; MCF7; HT_HG-U133A	GIT1 ESR1 ITGB4 DDX3X MINDY3 TMOD1 TOP3B	3.11e-04	193	151	7	3322_DN
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	ATRX ESR1 LIG4 USP5 SH2D4A CAMSAP1 COQ7	3.21e-04	194	151	7	6927_UP
Drug	Phenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A	ESR1 GRM8 ITGB4 NSD3 LIG4 TMOD1 CNGB1	3.21e-04	194	151	7	4538_UP
Drug	Galanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A	B4GALT7 ESR1 NCAPH2 RUFY3 SERPINB9 TMOD1 EDRF1	3.21e-04	194	151	7	2787_DN
Drug	Delcorine; Down 200; 8.4uM; PC3; HT_HG-U133A	B4GALT7 DOCK10 NCAPH2 NSD3 ATM COQ7 LRRC23	3.21e-04	194	151	7	4275_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	B4GALT7 EMC1 ESR1 NCAPH2 URB2 GRM8 ATM	3.21e-04	194	151	7	6958_DN
Drug	(-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A	EMC1 ESR1 MAP3K12 MYOF VPS13D ATM PLEC	3.21e-04	194	151	7	3539_DN
Drug	Fusaric acid [536-69-6]; Up 200; 22.4uM; HL60; HT_HG-U133A	NCAPH2 MINDY3 USP5 VPS13D MTUS1 COQ7 LRRC23	3.21e-04	194	151	7	1308_UP
Drug	Androsterone [53-41-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A	SLC11A2 ATRX GIT1 ESR1 NCAPH2 DDX3X ATM	3.21e-04	194	151	7	2650_DN
Drug	Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A	EMC1 ESR1 MYOF VPS13D TMOD1 ATM SEMA4A	3.31e-04	195	151	7	4412_DN
Drug	ST021200; Down 200; 10uM; PC3; HT_HG-U133A	ROR1 DDX3X VPS13D ZNF667 PLEC VAV2 LRRC23	3.31e-04	195	151	7	7493_DN
Drug	Medrysone [2668-66-8]; Down 200; 11.6uM; PC3; HT_HG-U133A	TRAF3IP1 RUFY3 LIG4 USP5 MTUS1 ADGRF5 COQ7	3.31e-04	195	151	7	3705_DN
Drug	Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; HL60; HT_HG-U133A	B4GALT7 DOCK10 MAP3K12 NSD3 MYOF SH2D4A TOP3B	3.31e-04	195	151	7	2705_DN
Drug	Amoxicillin [26787-78-0]; Up 200; 11uM; MCF7; HT_HG-U133A	SERHL2 HIF3A ITGB4 MINDY3 LIG4 TMOD1 ADGRF5	3.31e-04	195	151	7	5385_UP
Drug	S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; PC3; HT_HG-U133A	SERHL2 TRAF3IP1 GIT1 DOCK9 ITGB4 ADH6 MTUS1	3.31e-04	195	151	7	4634_UP
Drug	Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A	SLC11A2 NCAPH2 RUFY3 LIG4 SERPINB9 ATM EDRF1	3.31e-04	195	151	7	3269_DN
Drug	Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; MCF7; HT_HG-U133A	EMC1 ESR1 NSD3 USP5 TMOD1 TBX10 CAMSAP1	3.31e-04	195	151	7	2245_DN
Drug	5-aza-2′-deoxycytidine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	ATRX ESR1 GRM8 VPS13D SEMA4A VAV2 COQ7	3.31e-04	195	151	7	920_UP
Disease	Adenoid Cystic Carcinoma	ATRX ERBIN ITGB4 KMT2C MORF4L1 ATM	1.16e-05	100	148	6	C0010606
Disease	Junctional epidermolysis bullosa with pyloric atresia	ITGB4 PLEC	2.50e-05	2	148	2	cv:C5676875
Disease	Epidermolysis Bullosa Simplex With Pyloric Atresia	ITGB4 PLEC	2.50e-05	2	148	2	C2677349
Disease	EPIDERMOLYSIS BULLOSA, JUNCTIONAL 5B, WITH PYLORIC ATRESIA	ITGB4 PLEC	2.50e-05	2	148	2	226730
Disease	autosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)	VPS13D VPS13A	7.47e-05	3	148	2	DOID:0111611 (implicated_via_orthology)
Disease	Epidermolysis bullosa with pyloric atresia	ITGB4 PLEC	7.47e-05	3	148	2	C1856934
Disease	Disorder of eye	SPATA7 FREM2 TTC21B SEMA4A CNGB1 CNGA1 CNGA3	1.02e-04	212	148	7	C0015397
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	FAN1 ATM SEMA4A	1.13e-04	19	148	3	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	FAN1 ATM SEMA4A	1.13e-04	19	148	3	C2936783
Disease	attention deficit hyperactivity disorder (is_implicated_in)	DOCK3 GIT1 GRM8	1.32e-04	20	148	3	DOID:1094 (is_implicated_in)
Disease	BREAST CANCER	ESR1 ATM NQO2	1.54e-04	21	148	3	114480
Disease	focal segmental glomerulosclerosis 1 (implicated_via_orthology)	ACTN4 ACTN3	2.47e-04	5	148	2	DOID:0111128 (implicated_via_orthology)
Disease	Klatskin's tumor (is_implicated_in)	PREX2 KMT2C	2.47e-04	5	148	2	DOID:4927 (is_implicated_in)
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	FAN1 ATM SEMA4A	2.95e-04	26	148	3	C0009405
Disease	Hereditary non-polyposis colorectal cancer syndrome	FAN1 ATM SEMA4A	3.31e-04	27	148	3	C1112155
Disease	Malignant tumor of breast	ESR1 ATM NQO2	3.31e-04	27	148	3	cv:C0006142
Disease	Breast neoplasm	ESR1 ATM NQO2	3.31e-04	27	148	3	cv:C1458155
Disease	Familial cancer of breast	ESR1 ATM NQO2	3.31e-04	27	148	3	cv:C0346153
Disease	Aplasia Cutis Congenita	ITGB4 PLEC	3.70e-04	6	148	2	C0282160
Disease	Hereditary Nonpolyposis Colorectal Cancer	FAN1 ATM SEMA4A	4.11e-04	29	148	3	C1333990
Disease	Parkinsonism (implicated_via_orthology)	SLC11A2 ESR1 GRM8	4.11e-04	29	148	3	DOID:0080855 (implicated_via_orthology)
Disease	melanoma	DOCK3 NCOA6 OSBPL6 TRPM8 ATM	4.45e-04	126	148	5	EFO_0000756
Disease	infertility (implicated_via_orthology)	ESR1 ATM	5.16e-04	7	148	2	DOID:5223 (implicated_via_orthology)
Disease	Retinitis pigmentosa	SPATA7 SEMA4A CNGB1 CNGA1	5.32e-04	74	148	4	cv:C0035334
Disease	Acute Confusional Migraine	ESR1 TRPM8	8.79e-04	9	148	2	C0521664
Disease	Status Migrainosus	ESR1 TRPM8	8.79e-04	9	148	2	C0338489
Disease	Abdominal Migraine	ESR1 TRPM8	8.79e-04	9	148	2	C0270858
Disease	Sick Headaches	ESR1 TRPM8	8.79e-04	9	148	2	C0700438
Disease	Cervical Migraine Syndrome	ESR1 TRPM8	8.79e-04	9	148	2	C0007852
Disease	Hemicrania migraine	ESR1 TRPM8	8.79e-04	9	148	2	C0018984
Disease	breast cancer (is_implicated_in)	NCOA6 ESR1 CDK1 ATM NQO2	9.80e-04	150	148	5	DOID:1612 (is_implicated_in)
Disease	Lewy body dementia	DHX8 MMRN1 RAB7B	9.90e-04	39	148	3	EFO_0006792
Disease	Neurodevelopmental Disorders	ANK2 NCKAP1 DDX3X KMT2C	1.26e-03	93	148	4	C1535926
Disease	Migraine Disorders	ESR1 TRPM8	1.88e-03	13	148	2	C0149931
Disease	Retinitis Pigmentosa	SPATA7 SEMA4A CNGB1 CNGA1	1.89e-03	104	148	4	C0035334
Disease	ocular hypertension, response to triamcinolone acetonide	SERHL2 LIPK ITGB4	1.92e-03	49	148	3	EFO_0006954, EFO_1001069
Disease	Majewski Syndrome	TRAF3IP1 TTC21B	2.19e-03	14	148	2	C0024507
Disease	leukemia	ESR1 LIG4 ATM	2.68e-03	55	148	3	C0023418
Disease	isocitrate measurement	PREP TRPM8	2.86e-03	16	148	2	EFO_0010505
Disease	Colorectal Carcinoma	NUSAP1 SLC11A2 ANK2 OBSCN ABCC6 PREX2 KMT2C SACS VPS13A EDRF1	2.94e-03	702	148	10	C0009402
Disease	Malignant neoplasm of breast	NCOA6 ANK2 C1orf87 ESR1 ROR1 AGR2 OBSCN DDX3X NUP133 DHX32 ATM NQO2 PLEKHA8	3.02e-03	1074	148	13	C0006142
Disease	Astrocytosis	GRM8 ITGB4	3.23e-03	17	148	2	C3887640
Disease	Psychoses, Substance-Induced	ESR1 PICK1	3.23e-03	17	148	2	C0033941
Disease	Gliosis	GRM8 ITGB4	3.23e-03	17	148	2	C0017639
Disease	Female Urogenital Diseases	AMHR2 ESR1	3.63e-03	18	148	2	C1720887
Disease	Chronic myeloproliferative disorder	CENPE LIG4	4.04e-03	19	148	2	C1292778
Disease	leukemia (implicated_via_orthology)	ATM DOT1L	4.04e-03	19	148	2	DOID:1240 (implicated_via_orthology)
Disease	Liver carcinoma	NUSAP1 CENPE ESR1 BID KMT2C MTUS1 CDK1 ATM	4.18e-03	507	148	8	C2239176
Disease	breast carcinoma (is_marker_for)	ESR1 MTUS1 ATM	4.49e-03	66	148	3	DOID:3459 (is_marker_for)
Disease	Psychoses, Drug	ESR1 PICK1	4.93e-03	21	148	2	C0033937

Protein segments in the cluster

Peptide	Gene	Start	Entry
LPYLQSDADMALKSL	URB2	526	Q14146
EKLNPDFLLEIVMEY	TTC21B	441	Q7Z4L5
MLELARLYLAQDDPD	TTC21B	921	Q7Z4L5
MEKLLIQISAEYDPS	NAIP	1131	Q13075
AYEPADTALLLDNMK	AGR2	151	O95994
LKIDENQLMYLPDSI	ERBIN	281	Q96RT1
LLLDMYKSAPKEQRD	RNF40	671	O75150
KLVADYMAEKLNLDP	ADH6	331	P28332
DSKAYSMILLPAEEE	CARMIL2	1171	Q6F5E8
LGKTLDQMEPYLIEL	DPH6	176	Q7L8W6
AEKYLDIPKMLDAED	ACTN4	231	O43707
LDPYMKKLAAELDQL	ACAP3	211	Q96P50
YIIPQMADSLDLSEL	GIT1	246	Q9Y2X7
EEIPDLKLAMENYVL	DOT1L	46	Q8TEK3
EEVYKQLMSELETLP	CCDC22	471	O60826
PEQLKMLSELKDEYD	DIAPH1	901	O60610
APESLMQALEDLDYL	DHX32	451	Q7L7V1
SASKELPYDLEDAMV	CAMSAP1	176	Q5T5Y3
ALDLFDYMLALDPSK	CDK13	971	Q14004
EMSEKPYILEAALIA	ARMCX3	131	Q9UH62
GENMLLEPALRYLKE	C1orf87	531	Q8N0U7
YMAPELLDKTLDLQD	AMHR2	386	Q16671
KLYSLDPEQKEMLIE	AP3B1	176	O00203
MLASLGKNPTDEYLD	MYL12A	56	P19105
SYPMVLLGNKIDLAD	RAB7B	116	Q96AH8
MLDLLQIPYDKGDAK	ITPR3	1206	Q14573
LLEEVPEEMKYLTSL	LRRC69	71	Q6ZNQ3
AMLAYTPLDEKSLAL	MORF4L1	311	Q9UBU8
DYMKDEFLPALSLQS	ANK2	2181	Q01484
IELDLNLLLDMYPET	RSPH10B	386	P0C881
IELDLNLLLDMYPET	RSPH10B2	386	B2RC85
PKEIQMLARDFLDEY	DDX3X	386	O00571
EMEYLQKRSDLLSPL	NUP133	836	Q8WUM0
VMKALDLVSDPEYIN	MINDY3	331	Q9H8M7
SALPLGKIMDYIQED	TRAF3IP1	596	Q8TDR0
SMFNEELDLPIDDKL	KMT2C	2771	Q8NEZ4
KLLLPLMLQYSDEFV	MED12L	271	Q86YW9
LEDDIVAKPNYLSTM	MGAT4B	266	Q9UQ53
PQIMYLEQELESLKA	MTUS1	1131	Q9ULD2
QKRDAMELPDYVLLT	PPFIBP1	881	Q86W92
YMLSELFQLDEPKKE	EDRF1	506	Q3B7T1
DLTYDMEILQPLLEQ	MMRN1	641	Q13201
MEETYTDSLDPEKLL	GTSF1	1	Q8WW33
ELEATKQYLMLDPNK	KIF26B	2041	Q2KJY2
EKPCILELMDDVLYE	FREM2	2196	Q5SZK8
MHDVDLLPLNEELDY	B4GALT7	161	Q9UBV7
EALVQMPYLERLDKE	LRRC23	291	Q53EV4
DMLASLGKNPTDEYL	MYL9	56	P24844
KNVVPLYDLLLEMLD	ESR1	531	P03372
LEFLPNLDIKAMYSS	DNAH12	1031	Q6ZR08
LVASVPKAMDYDLLL	LAMB2	611	P55268
QPELYLLNTMDADSL	SLC11A2	551	P49281
SLYLPAMEKQLAILD	PLEKHA8	491	Q96JA3
MIIPSLEELDSLKYS	NUSAP1	1	Q9BXS6
DLYAMNLEPRATDKD	NQO2	41	P16083
YGVEMTNLPLDKLSE	RALGAPA2	656	Q2PPJ7
LEAMLYAIDQINKDP	GRM8	76	O00222
LESPVDLYILMDFSN	ITGB4	126	P16144
LLDKASETDDPYERM	OSBPL6	611	Q9BZF3
PEALMQALEDLDYLA	DQX1	436	Q8TE96
NISPEEEYKIACLLM	NCKAP1	986	Q9Y2A7
LEIDNSELLYMLESP	PABPC3	581	Q9H361
YLKNDPEKLDAFIMD	GRIN3A	831	Q8TCU5
KFKDYLETMAPELLE	OBSCN	7826	Q5VST9
MVLDDLPNLEDIYTS	NCOA6	1	Q14686
KLPEADDIQYPSMLL	PREP	621	P48147
DENLLKMVRDNPLYI	PIKFYVE	1976	Q9Y2I7
AEEYLSKQDLLFLDM	ATM	886	Q13315
MNELTELYTFEPDLL	ATRX	2201	P46100
KMEPLATVESLEQYL	HECTD1	1021	Q9ULT8
LDLPRNLTANEKYEM	HYDIN	1496	Q4G0P3
EIEKFLDPDMYSLLE	GPN3	186	Q9UHW5
KDPEMLVDLQYSLAN	DOCK10	1676	Q96BY6
DPEMLIDLQYSLAKS	DOCK11	1596	Q5JSL3
MPGDIRNDLYLTLEK	DOCK3	416	Q8IZD9
NDPEMLVDLQYSLAK	DOCK9	1591	Q9BZ29
KPEYVSGLMDELDIL	LIG4	451	P49917
LDLANEVDYAPSLMA	CDIN1	86	Q9Y2V0
ELIYEDSMDLIAKLP	CS	196	O75390
LMILLEYKIPRNEAD	CNTF	126	P26441
LMEEDPEKYEELLQL	COQ7	156	Q99807
YRQALDMILDLEPDE	CSNK2B	46	P67870
LEQLLQAYPRDMEKE	BID	131	P55957
DLKSPNMLITYDDVV	MAP3K12	236	Q12852
QLKGLYEEISMPLLA	ITIH6	461	Q6UXX5
NKYLPELMAEKDSLD	KHDRBS1	101	Q07666
LMEDLLKLPFTDTEQ	AHCTF1	921	Q8WYP5
SLLLPVMDQDYAKVL	EMC1	626	Q8N766
PEMIDYEGTQKLLAL	DNAH2	4166	Q9P225
FLLESDEMENLLTYK	SERHL2	136	Q9H4I8
QLLQSYMKLLLPDDE	INPP5F	601	Q9Y2H2
LNAYPSEKEMLKELL	SACS	2536	Q9NZJ4
EMLGAELLSNLYDKL	IPO13	436	O94829
PLRMKDNDLLVTELY	KCTD3	346	Q9Y597
IKMDLSYSLESIEDP	CENPE	606	Q02224
LIDPDLTQYAIIMLD	DHX8	671	Q14562
FLLESDEMENLLTYK	SERHL	136	Q9NQF3
MTKLEYEEIALDLTP	FAN1	431	Q9Y2M0
YNSLIFLKPNLEMLD	RNFT2	241	Q96EX2
KKELLSEFYEPNALM	RUFY3	186	Q7L099
LLEAEYMSELLEPSL	RIN1	556	Q13671
DVDIPDKLRSLLMYA	ABCC6	1056	O95255
LKAVDPMRATYLDDL	RABGGTA	411	Q92696
PETIDLGALYLSMKD	PLEK	121	P08567
DADALDLEMLAPYIS	HIF3A	481	Q9Y2N7
MLVVLPKLDGSLDEY	SMG1	2481	Q96Q15
LQDSYLLPISEDKVM	SEMA4A	156	Q9H3S1
EKEALQLMATYLPKD	PSMD1	416	Q99460
QLLDDYKEGDLRIMP	SPIN2A	176	Q99865
QDEMLPTYLKDLSIS	ADGRF5	741	Q8IZF2
AEKYLDIPKMLDAED	ACTN3	226	Q08043
LDENGLDLLSKMLIY	CDK1	256	P06493
DLLMDLLKNPKIADY	CIP2A	256	Q8TCG1
ADLDAVPMSLSYEEL	NCAPH2	456	Q6IBW4
CLSKDDLMEALTEYP	CNGA1	571	P29973
KDDLMEALTEYPEAK	CNGA3	581	Q16281
PDKMRLDLAIDVNYN	CNGB1	941	Q14028
DMLYLKDLAFVDPED	CNNM3	361	Q8NE01
ELNKDSYLTLDEPMN	ROR1	51	Q01973
DSLADYALLMDFIPL	TBX10	106	O75333
LSPIQKDLYEDVMLE	ZNF667	31	Q5HYK9
PDYLTEAELITLMEK	TOP3B	491	O95985
MLENYRNLLSLAEPK	ZNF343	91	Q6P1L6
LSYSIQDLLPEQDMK	ZNF678	31	Q5SXM1
EMLTPEEKALLYEAI	VPS13A	456	Q96RL7
DDYDIALMRLSKPLT	TMPRSS13	411	Q9BYE2
LDPAQKNLYKDVMLE	ZNF177	31	Q13360
MLLNEKVLPLAYSQE	MINPP1	436	Q9UNW1
EVLLPKFKLQEDYDM	SERPINB9	266	P50453
SNDPVAYALAEMLKE	TMOD1	236	P28289
YASQALEELMPLLKL	STKLD1	66	Q8NE28
IMPKDEDILQLAYSQ	ARHGAP23	151	Q9P227
QLLDDYKEGDLRIMP	SPIN2B	176	Q9BPZ2
LEKLFELSEAYPINM	SLC4A10	641	Q6U841
DDFLEVNSMKELYLL	SOGA1	696	O94964
LDMNYDLLLDPSEIN	SPOCK1	256	Q08629
LSEMYIDPDLLAELS	SH2D4A	6	Q9H788
LDMLLSAPKDENEIF	SPATA7	471	Q9P0W8
LYILPKEDRESLQMA	ACP6	286	Q9NPH0
AAYVDKLMRPLNALD	PREX2	1466	Q70Z35
SIYNALKKDLLPSDM	PLEC	3176	Q15149
DYLSAMVEPLDLKEE	nan	451	Q6ZUG5
YLLNESNRAELMKLP	NSD3	891	Q9BZ95
LKIQPAELGDSAMYL	TRBV11-1	96	A0A0K0K1C0
SLPAELENMKQLSYL	PHLPP1	751	O60346
LHDMYIDPELLAELS	SH2D4B	6	Q5SQS7
AKIMEDLLSSYPDLA	TTC37	406	Q6PGP7
TLEDIEKNYMSPLRL	VAV2	216	P52735
LMDDFTRDPLYILDN	TRPM8	241	Q7Z2W7
MLTDLNTYLNKAIPD	PICK1	231	Q9NRD5
LDDAEPYLLTMAKKA	TERF2	271	Q15554
VPMDAALNKEELLEY	USP5	491	P45974
LLMEDLLEKNPDSKY	VPS13D	1671	Q5THJ4
ADLMYGDIELLKDPQ	KIAA1958	576	Q8N8K9
SLDEMAKYDLPATIN	LIPK	141	Q5VXJ0
LLKIYRAEDIPQMDD	MYOF	361	Q9NZM1