Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone binding

NAP1L2 HAT1 CHD1 TAF1 TSPYL2

2.01e-04265415GO:0042393
GeneOntologyMolecularFunctionleucine zipper domain binding

AATF PAWR

3.69e-0414412GO:0043522
DomainA1pp

PARP14 MACROD2

1.59e-049402SM00506
DomainMacro

PARP14 MACROD2

1.59e-049402PF01661
DomainMacro_dom

PARP14 MACROD2

1.99e-0410402IPR002589
DomainMACRO

PARP14 MACROD2

1.99e-0410402PS51154
DomainNAP

NAP1L2 TSPYL2

5.96e-0417402PF00956
DomainNAP_family

NAP1L2 TSPYL2

5.96e-0417402IPR002164
Domain-

SACS SMCHD1

8.29e-04204023.30.565.10
DomainHATPase_C

SACS SMCHD1

9.15e-0421402IPR003594
DomainUbiquitin-rel_dom

AFDN SACS PLEKHG5

7.11e-03184403IPR029071
DomainDH_1

PLEKHG5 VAV1

8.04e-0363402PS00741
DomainRhoGEF

PLEKHG5 VAV1

9.32e-0368402SM00325
DomainDH_2

PLEKHG5 VAV1

9.85e-0370402PS50010
DomainRhoGEF

PLEKHG5 VAV1

9.85e-0370402PF00621
DomainDH-domain

PLEKHG5 VAV1

1.01e-0271402IPR000219
Domain-

PLEKHG5 VAV1

1.01e-02714021.20.900.10
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

AATF CHD1 PARP14 ARPC5 SMNDC1 SMCHD1 HNRNPU

1.36e-0734041729478914
Pubmed

AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4.

AATF PAWR

1.36e-06241214627703
Pubmed

NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.

AATF PLEKHG5 VAV1

1.82e-054341312376548
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

AFDN AATF CHD1 PAWR MGA SACS SMCHD1 HNRNPU

2.21e-05102441824711643
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

AATF CHD1 TAF1 MGA ARPC5 SMCHD1

3.59e-0553341630554943
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

PRR12 ZFHX2 FAM163B TAF1 SMCHD1 NEK11

4.36e-0555241610737800
Pubmed

The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.

TAF1 TAF7L

4.86e-05941212665565
Pubmed

Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).

AATF PLEKHG5 VAV1

4.97e-056041312787561
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

AFDN TAF1 SMCHD1 HNRNPU

9.64e-0520341422083510
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

AFDN AATF CHD1 TAF1 MGA SMCHD1 HNRNPU

1.14e-0495441736373674
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

HAT1 CHD1 TAF1 IRX2 SMNDC1 TFAP2C SMCHD1

1.66e-04101441732416067
Pubmed

Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3.

CCRL2 SACM1L

2.05e-041841212461651
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

CHD1 PARP14 TFAP2C SMCHD1 TSPYL2

2.19e-0446941527634302
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

PRR12 TAF1 MGA SMCHD1

2.79e-0426841433640491
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

HAT1 PRKAR2B SACS SMCHD1 HNRNPU

2.89e-0449841536634849
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

PRR12 CHD1 MGA

2.93e-0410941333554859
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TAF1 MGA IRX2 CFAP36 VAV1 TAF7L TSPYL2

2.98e-04111641731753913
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

HAT1 TAF1 MGA SMCHD1

3.43e-0428341430585729
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

CHD1 TAF1 MGA

4.27e-0412441320850016
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

PRR12 AATF CHD1 ARPC5 HNRNPU TSPYL2

4.45e-0484741635850772
Pubmed

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

ETAA1 PRKAR2B NEK11

5.96e-0413941325476789
Pubmed

HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres.

HAT1 HNRNPU

6.17e-043141220080577
Pubmed

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

TAF1 MGA

6.17e-043141215960975
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

CHD1 MGA DOCK11 PLEKHG5 SMNDC1 VAV1

6.72e-0491641632203420
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

HAT1 CHD1 TAF1 MGA SMCHD1

7.16e-0460841536089195
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

PRR12 AATF MGA SMNDC1 TFAP2C SMCHD1 HNRNPU

7.21e-04129441730804502
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

HAT1 AATF MGA TFAP2C

7.53e-0434941425665578
Pubmed

Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

PLEKHG5 VAV1

9.28e-043841211756498
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

AATF TAF1 VAV1 SMCHD1

9.35e-0437041422922362
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

HAT1 AFDN AATF PAWR CFAP36 HNRNPU SACM1L

9.94e-04136741732687490
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

HAT1 AATF CHD1 SMNDC1 SMCHD1 HNRNPU

1.00e-0398941636424410
Pubmed

Characterization of the DOT1L network: implications of diverse roles for DOT1L.

CHD1 HNRNPU

1.08e-034141220431927
InteractionDCPS interactions

AATF CHD1 PARP14 ARPC5 SMNDC1 SMCHD1 HNRNPU

1.31e-05394417int:DCPS
Cytoband1q25.3

SHCBP1L ARPC5

3.56e-04314121q25.3
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

HAT1 TAF1

1.12e-0417172486
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK11 PLEKHG5 VAV1

8.81e-04206173682
CoexpressionCHEOK_RESPONSE_TO_MERCAPTOPURINE_AND_HD_MTX_DN

AATF SACS SMCHD1

7.98e-0625413M7910
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

AFDN MGA NEK11 HNRNPU TRAK1

4.33e-0716641532d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

IFIH1 CHD1 PARP14 SMCHD1 HNRNPU

1.01e-061974155c33454b10023decd2f5ccda9229b6512659711e
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

IFIH1 CHD1 PARP14 SMCHD1 HNRNPU

1.03e-0619841544417089b62056269cac38d3134ff209c05b7007
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFIH1 CHD1 PARP14 SMCHD1 HNRNPU

1.03e-0619841528ef3fc4c17dcb765537b75917f7db78baa522db
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IFIH1 CHD1 PARP14 SMCHD1 HNRNPU

1.09e-0620041512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellmild-B_intermediate|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PAWR PARP14 SMCHD1 TRAK1 MACROD2

1.09e-06200415fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCellmild_COVID-19_(asymptomatic)-B_cell|World / disease group, cell group and cell class (v2)

NAP1L2 PRKAR2B PAWR MACROD2

1.34e-05158414afa8fa21c39c2192c1e23a4660011d63d58b733f
ToppCellmild_COVID-19_(asymptomatic)-B_cell|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

NAP1L2 PRKAR2B PAWR MACROD2

1.55e-05164414e4d43af7eb04d55328791b554bdf3a7ce6818027
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

CHD1 SMCHD1 HNRNPU TSPYL2

1.83e-051714142e9a20f8980b78325c52065a9c14ab3656267c05
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIH1 CHD1 PARP14 SMCHD1

2.14e-0517841401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CHD1 SMCHD1 HNRNPU TSPYL2

2.59e-05187414e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

CHD1 PARP14 SMCHD1 TSPYL2

2.65e-05188414ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

AFDN PAWR IRX2 MACROD2

2.65e-05188414eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAWR PARP14 TRAK1 MACROD2

2.71e-05189414b13f315f617840eb5143a4e8a33a657c20365c21
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PAWR IRX2 MYO3B MACROD2

2.82e-0519141463aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCellCOPD-Epithelial-Club|COPD / Disease state, Lineage and Cell class

PAWR IRX2 TFAP2C MACROD2

2.82e-05191414c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCellMild/Remission-B_activate-7|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

IFIH1 PARP14 SMCHD1 MACROD2

2.82e-05191414382686d62f7b8576c44bb9726a4e10dc26fd348e
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PAWR IRX2 MYO3B MACROD2

2.88e-05192414450baeb5c3df7a9445472530002ce38f177a333c
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

IRX2 TFAP2C MYO3B MACROD2

2.94e-05193414b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IRX2 TFAP2C MYO3B MACROD2

2.94e-05193414b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAWR PARP14 SMCHD1 MACROD2

2.94e-05193414ac227ddabfb3f021b1b39dba73f898517cd5a58e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAWR PARP14 SMCHD1 MACROD2

2.94e-05193414f4135615ee0118eec9e221becdd67888e0c2a112
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

IFIH1 CHD1 PARP14 SMCHD1

2.94e-051934147256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AFDN DNAAF9 MYO3B MACROD2

3.06e-051954146477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NAP1L2 SMCHD1 HNRNPU TSPYL2

3.12e-05196414ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellPCW_10-12-Epithelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PAWR IRX2 MYO3B MACROD2

3.12e-051964149bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCellPCW_10-12-Epithelial-Epithelial_airway|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PAWR IRX2 MYO3B MACROD2

3.24e-051984149a12e5e47236433e512c668005fe3f8be6fde95c
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PARP14 SMCHD1 HNRNPU TSPYL2

3.31e-05199414f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellBAL-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

IFIH1 CCRL2 PARP14 SMCHD1

3.31e-05199414c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCelllymphoid-NK_cell-NK_cell|NK_cell / Lineage, cell class and subclass

CHD1 SMNDC1 SMCHD1 TSPYL2

3.31e-05199414945fbf5845403a8b22d04963f50ad69c414b6153
ToppCellCOVID-19|World / Disease, condition lineage and cell class

CHD1 PARP14 SMCHD1 HNRNPU

3.37e-052004147dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellmild-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PAWR PARP14 SMCHD1 MACROD2

3.37e-05200414222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCellBiopsy_Other_PF-Epithelial-SCGB3A2+|Biopsy_Other_PF / Sample group, Lineage and Cell type

PAWR IRX2 TFAP2C MACROD2

3.37e-05200414631550dc34bcb605ab726645f4024d7828bb7975
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYO3B TAF7L CCER1

4.90e-057741310969743351c49a1d6d8ae1ef93098e7786ca3fe
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PRKAR2B ZNF839 NEK11

3.46e-041494134034805c4eefb8bfb3a357273ccbdb77283ea4a5
ToppCellMS-CD4-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

IFIH1 PARP14 SMCHD1

3.67e-04152413b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

CHD1 SMCHD1 TSPYL2

3.96e-041564131545169694f686d28648a68b552c2ae606599d66
ToppCellMyeloid-Myeloid-F|Myeloid / shred on cell class and cell subclass (v4)

IFIH1 CCRL2 PARP14

3.96e-04156413d6317843ae5c5749452889e768c187a9d9e8c7fe
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRR12 ZFHX2 IRX2

4.03e-041574134766f7d545bf2d775390589460677519cb92f4d5
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_naive|lymph-node_spleen / Manually curated celltypes from each tissue

PAWR COMP MACROD2

4.11e-041584137098847804dd90fa1dd74536e4e90f989b630fe4
ToppCell10x5'-blood-Lymphocytic_B-ABC_aged-B_memory|blood / Manually curated celltypes from each tissue

ZFHX2 PAWR MACROD2

4.58e-041644130424b23fc540580e7c15c50a7a03dff7c25014fa
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV5/7_gdT|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAP1L2 SACS VAV1

4.91e-04168413235c368669c017e13a7312fce3d8b91d7d106c7a
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETAA1 MYO3B TSPYL2

4.91e-04168413182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l12-15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCRL2 CD5L VAV1

5.00e-04169413f2f2ac2c9991c7cbc62e24a633e58f98b6274e6b
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

PAWR SACS DOCK11

5.26e-0417241336a96714a0eb6ac438648135336c9791881ddadb
ToppCellprimary_auditory_cortex_(A1C)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHCBP1L VAV1 MYO3B

5.26e-0417241320ea9db009370aa6235365ce93e153eb5b28db94
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SACS TRAK1 MACROD2

5.44e-04174413ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 TFAP2C NEK11

5.53e-04175413284fdc7a9d303636a637041846850d19d114861a
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IFIH1 PARP14 SMCHD1

5.53e-0417541397616bb5c127284aa9e67bc336dfcf29e137164b
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ETAA1 HAT1 SMCHD1

5.62e-041764139e719e6323597ecfc758c957256872cd4ae24d4d
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIH1 IRX2 DOCK11

5.72e-041774131dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAWR DOCK11 MYO3B

5.72e-041774132b675840b7d2bb536c2c600936733bd9e97e7120
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

AFDN PAWR TRAK1

5.72e-0417741337d1abe1a9d8f2b8f4d146bbf1db94104eab6593
ToppCellBAL-Control-cDC_1|Control / Compartment, Disease Groups and Clusters

IFIH1 PARP14 SMCHD1

5.72e-04177413aa021f6d62e9d740c5ea499faaf875de835a2865
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIH1 IRX2 DOCK11

5.72e-04177413426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-11|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PAWR PARP14 MACROD2

5.72e-041774133535575686c9700ab72700aae6f2070ebbb50044
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

COMP IRX2 MACROD2

5.81e-04178413f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

IFIH1 PARP14 SMCHD1

5.91e-04179413af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellE18.5-samps-Mesenchymal-Pericyte|E18.5-samps / Age Group, Lineage, Cell class and subclass

PRKAR2B CCRL2 DOCK11

6.00e-041804130b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IRX2 TFAP2C TAF7L

6.10e-04181413faff2a34e391d053a17c926540e6cb46d94dd629
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IRX2 TFAP2C TAF7L

6.10e-0418141358651853f9c715075889856793df66ebe00c04f1
ToppCellCOPD-Epithelial-Basal|World / Disease state, Lineage and Cell class

PAWR TFAP2C MACROD2

6.10e-041814136d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IRX2 TFAP2C TAF7L

6.10e-041814135a9c332c0bf07cc20eaf8cf77b45e73668a6467d
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IRX2 TFAP2C TAF7L

6.10e-04181413488a517f6e5543b648a2e72e0e04332fad776de6
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD1 SMCHD1 HNRNPU

6.20e-04182413eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCellremission-B_naive|World / disease stage, cell group and cell class

PAWR PARP14 MACROD2

6.20e-04182413cc1dfd2de35aee1a26f7efd78e108b60a3556ec5
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD1 SMCHD1 HNRNPU

6.30e-0418341328cbf909424f3be4491d49832f0aca0386560814
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

IFIH1 PARP14 SMCHD1

6.30e-041834138f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

IFIH1 PARP14 MACROD2

6.30e-04183413dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD1 SMCHD1 HNRNPU

6.30e-041834133fa608aa6b119869ec3280dc388dfee57160e63a
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 PAWR COMP

6.30e-04183413b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

PAWR TFAP2C MACROD2

6.30e-041834130f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHD1 PARP14 SMCHD1

6.50e-04185413e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIH1 IRX2 DOCK11

6.60e-041864134bb54043f944a979db91bde9a86dd66f498c7658
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFDN PAWR SACS

6.60e-041864130ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

PAWR PARP14 MACROD2

6.60e-04186413f352c63666273defea3e57ba3a3bfad52c4ea65b
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

AFDN PAWR IRX2

6.60e-0418641309d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PARP14 TRAK1 MACROD2

6.60e-0418641355b239834b96b1f7787ec77a7d19796d617bbbf0
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

PAWR TFAP2C MACROD2

6.60e-041864133006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PAWR PARP14 MACROD2

6.60e-04186413e2d265003aaea1acaf618d3f102c9933c19102e6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAWR DOCK11 MYO3B

6.60e-041864136379609b7ace80683f5754b16aa77f11b43766ae
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PAWR PARP14 MACROD2

6.71e-04187413e7970ec1507adfa91a296489166142cb9400421f
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

IRX2 MYO3B MACROD2

6.71e-04187413db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IRX2 MYO3B MACROD2

6.81e-041884130d86044bc340e3efb90d0022dd299873639d831c
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

IFIH1 PARP14 SMCHD1

6.81e-041884136f8946d4710f6e32c937213f99b790b098b8819c
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

IRX2 MYO3B MACROD2

6.81e-04188413beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

IRX2 MYO3B MACROD2

6.81e-041884133cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CHD1 SMCHD1 TSPYL2

6.81e-04188413939790f133eac9c12d08db6ddb5f08f5107844e3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAWR PARP14 TRAK1

6.92e-04189413886dceacf96e2b6750c146a381da0bf96a2bb15b
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIH1 IRX2 DOCK11

6.92e-04189413ce3fbaf9642785c8adf6edaeae20998bca558928
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IRX2 MYO3B MACROD2

6.92e-041894137659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell10x_3'_v3-spleen_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CHD1 CD5L SMCHD1

6.92e-041894130fe8901e10c619c93b7788792da1706a32102c6e
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 PAWR COMP

6.92e-041894138e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCellfacs-Skin-nan-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCRL2 TFAP2C TAF7L

6.92e-041894136c71e81373cb7822de23c193a6350b6df9f567bc
ToppCellCTRL-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

PARP14 TRAK1 MACROD2

6.92e-0418941314f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCellSmart-seq2-spleen_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CHD1 CD5L SMCHD1

6.92e-04189413b0244a9d1b5c8ad4708750b691184f3491b13900
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

PAWR IRX2 MACROD2

6.92e-04189413f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COMP IRX2 MACROD2

6.92e-04189413e059be2965cca70ff5576df055d0af1775b76e00
ToppCellIPF-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

CHD1 VAV1 SMCHD1

6.92e-041894135c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 PAWR COMP

6.92e-04189413fb2253b8463d08b3d28e952a31a23dea2c2d986b
ComputationalNeighborhood of CUL1

AATF ARPC5 SMNDC1 HNRNPU

2.89e-0572274MORF_CUL1
ComputationalNeighborhood of DEK

HAT1 AATF ARPC5 SMNDC1 HNRNPU

4.46e-04264275MORF_DEK
ComputationalGenes in the cancer module 301.

ZFHX2 VAV1 SMCHD1 NEK11

6.06e-04158274MODULE_301
ComputationalGenes in the cancer module 238.

ZFHX2 VAV1 SMCHD1 NEK11

6.97e-04164274MODULE_238
Diseasebeta-hydroxyisovalerate measurement

PLEKHG5 HPD

1.53e-0414392EFO_0800125
Diseasecoronary aneurysm

MYO3B MACROD2

9.85e-0435392EFO_1000881
DiseaseRS-6-hydroxywarfarin measurement

PARP14 TRAK1 MACROD2

1.13e-03155393EFO_0803328
Diseaseinterleukin 12 measurement

SACS MACROD2

2.25e-0353392EFO_0004753
DiseaseEndometrial Neoplasms

PAWR TSPYL2

2.69e-0358392C0014170
DiseaseIntellectual Disability

PRR12 TAF1 SACS HNRNPU

2.81e-03447394C3714756

Protein segments in the cluster

PeptideGeneStartEntry
VAYNEEEEEEDCSLA

AFDN

1731

P55196
ESDEAEQCDKYDAQA

CCRL2

21

O00421
TDNVKYEEDCEDRHD

TFAP2C

6

Q92754
DFVEQKCEVFDDEEE

CFAP36

31

Q96G28
GDVCQDDFDADKVVD

COMP

501

P49747
CEQEEVYDCSHDEDA

CD5L

106

O43866
SEEDDDEEDYDNDKR

CHD1

216

O14646
VEEEEEKKNDDEEEY

CCER1

276

Q8TC90
EKKNDDEEEYDQEVC

CCER1

281

Q8TC90
DEEEYDQEVCDAKEA

CCER1

286

Q8TC90
DQEVCDAKEASEEEE

CCER1

291

Q8TC90
VDEYDENKFVDEEDG

ARPC5

16

O15511
CEYKSDSEDCDDEEM

NAP1L2

166

Q9ULW6
AECLDEYEDDEAGQK

PAWR

171

Q96IZ0
KNNCVEYIEDDEEHV

MGA

2336

Q8IWI9
CETEDYGEKFDENDV

HNRNPU

391

Q00839
YCEESDEEEEEIALE

NEK11

486

Q8NG66
CKDKYDDLEDDEDDD

IRX2

256

Q9BZI1
EADDVDDDLLYQACD

ETAA1

601

Q9NY74
DECIKDFDEKEYQEL

PARP14

1461

Q460N5
DENFDCVEADDVEGK

HAT1

96

O14929
NHVFEIDEDCEKDED

DOCK11

141

Q5JSL3
QYYCCKKDESEEDEE

FAM163B

31

P0C2L3
DEYCDGDEDEDDLKK

IFIH1

651

Q9BYX4
CMTENEYEDEEAAEE

DNAAF9

131

Q5TEA3
CAEAYNPDEEEDDAE

PRKAR2B

116

P31323
EKFYVEACDDGADDV

SACM1L

16

Q9NTJ5
VDYCFKDAEENEIEV

SACS

3136

Q9NZJ4
ASEEAVEDCKDEDFA

MACROD2

291

A1Z1Q3
VEDCKDEDFAKDENI

MACROD2

296

A1Z1Q3
DGVKDIAFEVEDCDY

HPD

91

P32754
EEEEEDCSEEYLERQ

TAF7L

356

Q5H9L4
DEDDEDDCFILEKAA

SMCHD1

451

A6NHR9
EDDYDADCEDIDCKL

TAF1

141

P21675
YCDEVLQDCKAEDAD

SHCBP1L

126

Q9BZQ2
AQEYEFEADEDKADV

PRR12

1096

Q9ULL5
EYDEDDLGAAEEQEC

AATF

116

Q9NY61
DVDLDEVYCLNDFEE

TRAK1

616

Q9UPV9
EEYDEDEDEDNACLR

PLEKHG5

301

O94827
EDFDKDQADYEDVIE

TSPYL2

611

Q9H2G4
KCYDDQTLEEEEEEA

ZFHX2

1691

Q9C0A1
DTVEEDEDLYDCVEN

VAV1

151

P15498
DEDLYDCVENEEAEG

VAV1

156

P15498
DCVENEEAEGDEIYE

VAV1

161

P15498
DYSELCVEEDEDQRE

ZNF839

166

A8K0R7
DGQCYEAEIEEIDEE

SMNDC1

86

O75940
KEDTVYDICNEDAVD

nan

111

Q8N402
YDICNEDAVDISDED

nan

116

Q8N402
VEDAEKYCLEDDLVN

MYO3B

336

Q8WXR4