Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K27 trimethyltransferase activity	EZH1 EZH2	1.00e-05	3	37	2	GO:0140951
GeneOntologyMolecularFunction	histone H3K27 methyltransferase activity	EZH1 EZH2	4.99e-05	6	37	2	GO:0046976
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	RNF144B RNF103 UBE3D MYLIP MSL2	5.83e-04	372	37	5	GO:0061630
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RNF144B RNF103 UBE3D MYLIP MSL2	7.91e-04	398	37	5	GO:0061659
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	RNF144B RNF103 UBE3D MYLIP MSL2	1.70e-03	473	37	5	GO:0004842
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme binding	RNF144B UBE3D	2.02e-03	36	37	2	GO:0031624
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	RNF144B RNF103 UBE3D MYLIP MSL2	2.41e-03	512	37	5	GO:0019787
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme binding	RNF144B UBE3D	2.75e-03	42	37	2	GO:0044390
GeneOntologyMolecularFunction	aminoacyltransferase activity	RNF144B RNF103 UBE3D MYLIP MSL2	2.84e-03	532	37	5	GO:0016755
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	EZH1 EZH2	3.01e-03	44	37	2	GO:0140938
GeneOntologyMolecularFunction	extracellular matrix structural constituent	FBLN5 VWF MUC2	5.04e-03	188	37	3	GO:0005201
GeneOntologyMolecularFunction	heparin binding	LRTM1 TENM1 ADAMTS3	5.35e-03	192	37	3	GO:0008201
GeneOntologyMolecularFunction	structural molecule activity	KRTAP29-1 FBLN5 VWF KRTAP16-1 MUC2 KRT40	5.52e-03	891	37	6	GO:0005198
GeneOntologyBiologicalProcess	hepatocyte homeostasis	EZH1 EZH2	2.96e-06	2	36	2	GO:0036333
GeneOntologyBiologicalProcess	response to tetrachloromethane	EZH1 EZH2	2.95e-05	5	36	2	GO:1904772
GeneOntologyBiologicalProcess	subtelomeric heterochromatin formation	EZH1 EZH2	1.06e-04	9	36	2	GO:0031509
GeneOntologyCellularComponent	intermediate filament	KRTAP29-1 KRTAP16-1 KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	5.03e-09	227	37	8	GO:0005882
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRTAP29-1 KRTAP16-1 KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	1.59e-08	263	37	8	GO:0045111
GeneOntologyCellularComponent	keratin filament	KRTAP29-1 KRTAP16-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.77e-08	97	37	6	GO:0045095
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	KRTAP29-1 KRTAP16-1 KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	1.44e-04	899	37	8	GO:0099513
GeneOntologyCellularComponent	supramolecular fiber	KRTAP29-1 FBLN5 KRTAP16-1 KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	1.66e-04	1179	37	9	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	KRTAP29-1 FBLN5 KRTAP16-1 KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	1.75e-04	1187	37	9	GO:0099081
GeneOntologyCellularComponent	ESC/E(Z) complex	EZH1 EZH2	4.08e-04	17	37	2	GO:0035098
GeneOntologyCellularComponent	heterochromatin	EZH1 EZH2 ZFP57	7.55e-04	101	37	3	GO:0000792
GeneOntologyCellularComponent	Golgi lumen	MUC19 MUC5B MUC2	9.42e-04	109	37	3	GO:0005796
GeneOntologyCellularComponent	PcG protein complex	EZH1 EZH2	3.82e-03	52	37	2	GO:0031519
GeneOntologyCellularComponent	extracellular matrix	MUC5B FBLN5 VWF ADAMTS3 MUC2	5.69e-03	656	37	5	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	MUC5B FBLN5 VWF ADAMTS3 MUC2	5.76e-03	658	37	5	GO:0030312
Domain	Keratin_B2_2	KRTAP29-1 KRTAP16-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.23e-10	39	37	6	PF13885
Domain	KAP	KRTAP29-1 KRTAP16-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.48e-09	58	37	6	IPR002494
Domain	TIL	MUC19 MUC5B VWF MUC2	6.38e-09	12	37	4	PF01826
Domain	C8	MUC19 MUC5B VWF MUC2	6.38e-09	12	37	4	PF08742
Domain	Unchr_dom_Cys-rich	MUC19 MUC5B VWF MUC2	9.20e-09	13	37	4	IPR014853
Domain	C8	MUC19 MUC5B VWF MUC2	9.20e-09	13	37	4	SM00832
Domain	TIL_dom	MUC19 MUC5B VWF MUC2	1.29e-08	14	37	4	IPR002919
Domain	VWFD	MUC19 MUC5B VWF MUC2	2.33e-08	16	37	4	PS51233
Domain	VWD	MUC19 MUC5B VWF MUC2	2.33e-08	16	37	4	SM00216
Domain	VWF_type-D	MUC19 MUC5B VWF MUC2	2.33e-08	16	37	4	IPR001846
Domain	VWD	MUC19 MUC5B VWF MUC2	2.33e-08	16	37	4	PF00094
Domain	CTCK_1	MUC19 MUC5B VWF MUC2	3.91e-08	18	37	4	PS01185
Domain	VWC_out	MUC19 MUC5B VWF MUC2	4.94e-08	19	37	4	SM00215
Domain	CT	MUC19 MUC5B VWF MUC2	9.29e-08	22	37	4	SM00041
Domain	Tesmin/TSO1-like_CXC	EZH1 EZH2 MSL2	1.43e-07	6	37	3	IPR033467
Domain	CXC	EZH1 EZH2 MSL2	1.43e-07	6	37	3	SM01114
Domain	Cys_knot_C	MUC19 MUC5B VWF MUC2	1.60e-07	25	37	4	IPR006207
Domain	CTCK_2	MUC19 MUC5B VWF MUC2	1.60e-07	25	37	4	PS01225
Domain	VWC	MUC19 MUC5B VWF MUC2	9.17e-07	38	37	4	SM00214
Domain	VWFC_2	MUC19 MUC5B VWF MUC2	9.17e-07	38	37	4	PS50184
Domain	Keratin_B2	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.13e-06	40	37	4	PF01500
Domain	VWF_dom	MUC19 MUC5B VWF MUC2	1.38e-06	42	37	4	IPR001007
Domain	EZH2_WD-Binding	EZH1 EZH2	3.82e-06	2	37	2	PF11616
Domain	CXC_dom	EZH1 EZH2	3.82e-06	2	37	2	IPR026489
Domain	CXC	EZH1 EZH2	3.82e-06	2	37	2	PS51633
Domain	EZH1/EZH2	EZH1 EZH2	3.82e-06	2	37	2	IPR021654
Domain	ZF_RING_1	RNF144B NFXL1 TRIM67 RNF103 MYLIP MSL2	2.10e-05	291	37	6	PS00518
Domain	ZF_RING_2	RNF144B NFXL1 TRIM67 RNF103 MYLIP MSL2	2.41e-05	298	37	6	PS50089
Domain	Znf_RING	RNF144B NFXL1 TRIM67 RNF103 MYLIP MSL2	3.98e-05	326	37	6	IPR001841
Domain	VWFC_1	MUC5B VWF MUC2	4.88e-05	36	37	3	PS01208
Domain	WxxW_domain	MUC5B MUC2	5.70e-05	6	37	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC2	5.70e-05	6	37	2	PF13330
Domain	VWC	MUC5B VWF	1.40e-03	28	37	2	PF00093
Domain	-	RNF144B TRIM67 RNF103 MYLIP MSL2	1.82e-03	449	37	5	3.30.40.10
Domain	Znf_RING/FYVE/PHD	RNF144B TRIM67 RNF103 MYLIP MSL2	2.00e-03	459	37	5	IPR013083
Domain	SET	EZH1 EZH2	2.98e-03	41	37	2	PF00856
Domain	RING	RNF144B TRIM67 RNF103 MYLIP	3.01e-03	305	37	4	SM00184
Domain	SET	EZH1 EZH2	3.74e-03	46	37	2	SM00317
Domain	SET_dom	EZH1 EZH2	4.41e-03	50	37	2	IPR001214
Domain	SANT	EZH1 EZH2	4.41e-03	50	37	2	SM00717
Domain	SET	EZH1 EZH2	4.41e-03	50	37	2	PS50280
Domain	SANT/Myb	EZH1 EZH2	4.76e-03	52	37	2	IPR001005
Domain	zf-C3HC4	TRIM67 RNF103 MYLIP	9.68e-03	223	37	3	PF00097
Domain	Cys-rich_flank_reg_C	LRTM1 NTRK3	1.37e-02	90	37	2	IPR000483
Domain	LRRCT	LRTM1 NTRK3	1.37e-02	90	37	2	SM00082
Domain	LRRNT	LRTM1 NTRK3	1.61e-02	98	37	2	IPR000372
Domain	LRRNT	LRTM1 NTRK3	1.61e-02	98	37	2	SM00013
Pathway	REACTOME_KERATINIZATION	KRTAP29-1 KRTAP16-1 KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	9.01e-09	217	29	8	M27640
Pathway	REACTOME_KERATINIZATION	KRTAP29-1 KRTAP16-1 KRTAP10-10 KRTAP10-1 KRTAP10-11 KRT40	5.73e-07	153	29	6	MM15343
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC19 MUC5B MUC2	1.02e-05	21	29	3	MM15706
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	MUC19 MUC5B ADAMTS3 MUC2	6.92e-05	109	29	4	MM15164
Pathway	BIOCARTA_PRC2_PATHWAY	EZH1 EZH2	2.22e-04	11	29	2	MM1548
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC19 MUC5B MUC2	2.48e-04	60	29	3	MM15636
Pathway	BIOCARTA_PRC2_PATHWAY	EZH1 EZH2	3.66e-04	14	29	2	M22025
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	KRTAP29-1 KRTAP16-1 KRTAP10-10 KRTAP10-1 KRTAP10-11 KRT40	4.67e-04	502	29	6	MM14537
Pathway	WP_INTERACTOME_OF_POLYCOMB_REPRESSIVE_COMPLEX_2_PRC2	EZH1 EZH2	4.82e-04	16	29	2	M39484
Pathway	KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119	EZH1 EZH2	9.20e-04	22	29	2	M47924
Pathway	KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES	EZH1 EZH2	1.39e-03	27	29	2	M47941
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	KRTAP29-1 EZH2 KRTAP16-1 KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	1.71e-03	1432	29	9	M509
Pubmed	A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.95e-09	16	37	4	15028290
Pubmed	Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair.	KRTAP29-1 KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-11	1.10e-08	69	37	5	18721477
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC19 MUC5B MUC2	2.21e-08	6	37	3	19110483
Pubmed	Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21.	KRTAP10-10 KRTAP10-1 KRTAP10-9	1.82e-07	11	37	3	14962103
Pubmed	The DNA sequence of human chromosome 21.	KRTAP16-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 DOP1B	3.01e-07	258	37	6	10830953
Pubmed	Dissecting the Roles of Polycomb Repressive Complex 2 Subunits in the Control of Skin Development.	EZH1 EZH2 KRT40	6.15e-07	16	37	3	26994968
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC19 MUC5B MUC2	8.94e-07	18	37	3	18834073
Pubmed	The competitive mechanism of EZH1 and EZH2 in promoting oral squamous cell carcinoma.	EZH1 EZH2	1.10e-06	2	37	2	38309675
Pubmed	Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2.	EZH1 EZH2	1.10e-06	2	37	2	32428001
Pubmed	Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres.	EZH1 EZH2	1.10e-06	2	37	2	9214638
Pubmed	PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs.	EZH1 EZH2	1.10e-06	2	37	2	28939884
Pubmed	EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair.	EZH1 EZH2	1.10e-06	2	37	2	21317239
Pubmed	Aberrant differential expression of EZH1 and EZH2 in Polycomb repressive complex 2 among B- and T/NK-cell neoplasms.	EZH1 EZH2	1.10e-06	2	37	2	27311868
Pubmed	Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1.	EZH1 EZH2	1.10e-06	2	37	2	8921387
Pubmed	Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions.	EZH1 EZH2	1.10e-06	2	37	2	25578878
Pubmed	The methyltransferases enhancer of zeste homolog (EZH) 1 and EZH2 control hepatocyte homeostasis and regeneration.	EZH1 EZH2	1.10e-06	2	37	2	25477280
Pubmed	EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation.	EZH1 EZH2	1.10e-06	2	37	2	30522506
Pubmed	The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2.	EZH2 MSMB	1.10e-06	2	37	2	17237810
Pubmed	[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].	MUC5B MUC2	1.10e-06	2	37	2	20873538
Pubmed	The role of EZH1 and EZH2 in development and cancer.	EZH1 EZH2	1.10e-06	2	37	2	36476271
Pubmed	Cloning and expression of a human/mouse Polycomb group gene, ENX-2/Enx-2.	EZH1 EZH2	1.10e-06	2	37	2	9473645
Pubmed	The complete cDNA sequence and structural polymorphism of the polypeptide chain of porcine submaxillary mucin.	VWF MUC2	1.10e-06	2	37	2	9407109
Pubmed	Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas.	EZH1 EZH2	1.10e-06	2	37	2	31747604
Pubmed	Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration.	EZH1 EZH2	1.10e-06	2	37	2	27526204
Pubmed	The murine polycomb-group genes Ezh1 and Ezh2 map close to Hox gene clusters on mouse chromosomes 11 and 6.	EZH1 EZH2	1.10e-06	2	37	2	10051331
Pubmed	EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer.	EZH1 EZH2	1.10e-06	2	37	2	30867289
Pubmed	EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy.	EZH1 EZH2	1.10e-06	2	37	2	27897169
Pubmed	Polycomb Repressive Complex 2 Proteins EZH1 and EZH2 Regulate Timing of Postnatal Hepatocyte Maturation and Fibrosis by Repressing Genes With Euchromatic Promoters in Mice.	EZH1 EZH2	1.10e-06	2	37	2	30689973
Pubmed	Signaling function of PRC2 is essential for TCR-driven T cell responses.	EZH1 EZH2	3.30e-06	3	37	2	29523590
Pubmed	Targeting EZH1 and EZH2 contributes to the suppression of fibrosis-associated genes by miR-214-3p in cardiac myofibroblasts.	EZH1 EZH2	3.30e-06	3	37	2	27823969
Pubmed	Ezh1 Targets Bivalent Genes to Maintain Self-Renewing Stem Cells in Ezh2-Insufficient Myelodysplastic Syndrome.	EZH1 EZH2	3.30e-06	3	37	2	30396150
Pubmed	Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner.	EZH1 EZH2	3.30e-06	3	37	2	26219303
Pubmed	The polycomb-group gene Ezh2 is required for early mouse development.	EZH1 EZH2	3.30e-06	3	37	2	11390661
Pubmed	Chronic Myelogenous Leukemia- Initiating Cells Require Polycomb Group Protein EZH2.	EZH1 EZH2	3.30e-06	3	37	2	27630126
Pubmed	Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells.	EZH1 EZH2	3.30e-06	3	37	2	22042701
Pubmed	Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells.	EZH1 EZH2	3.30e-06	3	37	2	23673358
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC5B MUC2	3.30e-06	3	37	2	19718741
Pubmed	Assessment of community efforts to advance network-based prediction of protein-protein interactions.	GRN KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	3.98e-06	630	37	7	36949045
Pubmed	Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.	MUC5B MUC2	6.60e-06	4	37	2	21596555
Pubmed	Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons.	EZH1 EZH2	6.60e-06	4	37	2	23932971
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5B MUC2	6.60e-06	4	37	2	23807779
Pubmed	Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling.	EZH1 EZH2	6.60e-06	4	37	2	37105173
Pubmed	EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.	EZH1 EZH2	6.60e-06	4	37	2	19026780
Pubmed	Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.	EZH1 EZH2	6.60e-06	4	37	2	19026781
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC5B MUC2	6.60e-06	4	37	2	25638393
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5B MUC2	6.60e-06	4	37	2	17471237
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC5B MUC2	6.60e-06	4	37	2	22269464
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5B MUC2	6.60e-06	4	37	2	14984930
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5B MUC2	6.60e-06	4	37	2	12676567
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5B MUC2	6.60e-06	4	37	2	29869461
Pubmed	Regulation of embryonic haematopoietic multipotency by EZH1.	EZH1 EZH2	6.60e-06	4	37	2	29342143
Pubmed	Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation.	EZH1 EZH2	6.60e-06	4	37	2	31189531
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC5B MUC2	1.10e-05	5	37	2	11062147
Pubmed	A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination.	EZH1 EZH2	1.10e-05	5	37	2	28320739
Pubmed	Differential expression of MUC genes in endometrial and cervical tissues and tumors.	MUC5B MUC2	1.10e-05	5	37	2	16188033
Pubmed	Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.	MUC5B MUC2	1.10e-05	5	37	2	24840470
Pubmed	PRC2 insufficiency causes p53-dependent dyserythropoiesis in myelodysplastic syndrome.	EZH1 EZH2	1.10e-05	5	37	2	32820269
Pubmed	Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: indication for separate Pc-G complexes.	EZH1 EZH2	1.10e-05	5	37	2	9584197
Pubmed	X chromosome reactivation and regulation in cloned embryos.	EZH1 EZH2	2.30e-05	7	37	2	15733677
Pubmed	M phase-specific association of human topoisomerase IIIbeta with chromosomes.	GRN FBLN5	3.07e-05	8	37	2	11549288
Pubmed	Loss of Ezh2 in the medial ganglionic eminence alters interneuron fate, cell morphology and gene expression profiles.	EZH1 EZH2	3.07e-05	8	37	2	38419656
Pubmed	Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation.	EZH1 EZH2	3.07e-05	8	37	2	20144788
Pubmed	New insights into BS69 functions.	EZH1 EZH2	3.07e-05	8	37	2	16565076
Pubmed	PRC2 directly methylates GATA4 and represses its transcriptional activity.	EZH1 EZH2	3.95e-05	9	37	2	22215809
Pubmed	EZH1 in germ cells safeguards the function of PRC2 during spermatogenesis.	EZH1 EZH2	3.95e-05	9	37	2	28254491
Pubmed	Ezh2-dependent methylation in oral epithelia promotes secondary palatogenesis.	EZH1 EZH2	3.95e-05	9	37	2	37435868
Pubmed	JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.	EZH1 EZH2	3.95e-05	9	37	2	20075857
Pubmed	Divergent Requirements for EZH1 in Heart Development Versus Regeneration.	EZH1 EZH2	4.93e-05	10	37	2	28512107
Pubmed	EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells.	EZH1 EZH2	4.93e-05	10	37	2	31451685
Pubmed	Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal.	EZH1 EZH2	6.02e-05	11	37	2	22438827
Pubmed	An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting.	EZH1 EZH2	6.02e-05	11	37	2	23273982
Pubmed	Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival.	EZH1 EZH2	7.22e-05	12	37	2	22312437
Pubmed	Maternal Ezh1/2 deficiency in oocyte delays H3K27me2/3 restoration and impairs epiblast development responsible for embryonic sub-lethality in mouse.	EZH1 EZH2	8.53e-05	13	37	2	35796552
Pubmed	Loss of G9a does not phenocopy the requirement for Prdm12 in the development of the nociceptive neuron lineage.	EZH2 NTRK3	1.15e-04	15	37	2	38167468
Pubmed	PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway.	EZH1 EZH2	1.31e-04	16	37	2	32937136
Pubmed	KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis.	EZH1 EZH2	1.31e-04	16	37	2	35212626
Pubmed	Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition.	EZH1 EZH2	1.48e-04	17	37	2	12589020
Pubmed	Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells.	EZH1 EZH2	1.67e-04	18	37	2	19303854
Pubmed	Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.	EZH1 EZH2	1.67e-04	18	37	2	20064376
Pubmed	Polycomb repressive complex 2 regulates normal development of the mouse heart.	EZH1 EZH2	1.86e-04	19	37	2	22158708
Pubmed	The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice.	EZH1 EZH2	1.86e-04	19	37	2	32554463
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	EZH1 ADAMTS3 ZMYM3	1.87e-04	104	37	3	9205841
Pubmed	An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.	GRN KRTAP10-1 KRTAP10-9 KRT40 MYLIP	2.04e-04	514	37	5	29892012
Pubmed	Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.	EZH1 EZH2	2.07e-04	20	37	2	22267199
Pubmed	Unravelling the transcriptional responses of TGF-β: Smad3 and EZH2 constitute a regulatory switch that controls neuroretinal epithelial cell fate specification.	EZH1 EZH2	2.75e-04	23	37	2	30779601
Pubmed	CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.	EZH1 EZH2	2.75e-04	23	37	2	31281901
Pubmed	Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation.	EZH1 EZH2	3.25e-04	25	37	2	26621269
Pubmed	Widespread macromolecular interaction perturbations in human genetic disorders.	GRN FBLN5 KRTAP10-1 KRTAP10-9 KRT40	3.84e-04	590	37	5	25910212
Pubmed	Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration.	EZH1 EZH2	4.39e-04	29	37	2	28049658
Pubmed	Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development.	EZH1 EZH2	5.69e-04	33	37	2	27414999
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	EZH1 EZH2	5.69e-04	33	37	2	26864203
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	FBLN5 VWF MUC2	5.81e-04	153	37	3	25037231
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	FBLN5 VWF MUC2	7.49e-04	167	37	3	22159717
Pubmed	A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis.	EZH2 NTRK3	7.56e-04	38	37	2	38346162
Pubmed	PRC1 sustains the integrity of neural fate in the absence of PRC2 function.	EZH1 EZH2	7.56e-04	38	37	2	34994686
Pubmed	Characterization of a first domain of human high glycine-tyrosine and high sulfur keratin-associated protein (KAP) genes on chromosome 21q22.1.	KRTAP15-1 KRTAP10-1	8.37e-04	40	37	2	12359730
Pubmed	Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.	MUC5B MUC2	8.80e-04	41	37	2	22675208
Pubmed	Hepatitis C virus infection protein network.	FBLN5 VWF	9.23e-04	42	37	2	18985028
Pubmed	Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos.	EZH1 EZH2	9.23e-04	42	37	2	38529784
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	KRTAP16-1 KRTAP15-1 SYT17 KRTAP10-9	1.01e-03	420	37	4	28065597
Interaction	HOXA1 interactions	GRN FBLN5 VWF KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	9.36e-09	356	36	9	int:HOXA1
Interaction	CREB5 interactions	RNF144B FBLN5 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	1.42e-08	164	36	7	int:CREB5
Interaction	LCE3E interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	6.93e-08	60	36	5	int:LCE3E
Interaction	MOBP interactions	KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	7.41e-08	23	36	4	int:MOBP
Interaction	LCE3C interactions	GRN KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.21e-07	67	36	5	int:LCE3C
Interaction	LCE1E interactions	GRN KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.31e-07	68	36	5	int:LCE1E
Interaction	OTX1 interactions	RNF144B GRN FBLN5 KRTAP10-1 KRTAP10-9 KRTAP10-11	3.02e-07	155	36	6	int:OTX1
Interaction	LCE1B interactions	GRN KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	4.03e-07	85	36	5	int:LCE1B
Interaction	FAM76B interactions	GRN FBLN5 KRTAP10-1 KRTAP10-9 KRTAP10-11	8.63e-07	99	36	5	int:FAM76B
Interaction	LCE3B interactions	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.33e-06	46	36	4	int:LCE3B
Interaction	C22orf39 interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11	1.72e-06	49	36	4	int:C22orf39
Interaction	ZNF625 interactions	KRTAP10-1 KRTAP10-9 KRT40	2.35e-06	15	36	3	int:ZNF625
Interaction	CTSZ interactions	EZH2 KRTAP10-10 KRTAP10-1 KRT40	3.64e-06	59	36	4	int:CTSZ
Interaction	ZNF587 interactions	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	4.00e-06	135	36	5	int:ZNF587
Interaction	KRTAP12-1 interactions	GRN KRTAP15-1 KRTAP10-1 KRTAP10-9	4.74e-06	63	36	4	int:KRTAP12-1
Interaction	CRCT1 interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11	5.71e-06	66	36	4	int:CRCT1
Interaction	NR1D2 interactions	KRTAP10-1 KRTAP10-9 KRT40 MYLIP	6.07e-06	67	36	4	int:NR1D2
Interaction	ZNF696 interactions	FBLN5 KRTAP10-9 KRT40 MSMB	6.44e-06	68	36	4	int:ZNF696
Interaction	LCE1D interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11	7.23e-06	70	36	4	int:LCE1D
Interaction	KRTAP5-7 interactions	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	7.65e-06	71	36	4	int:KRTAP5-7
Interaction	NUFIP2 interactions	GRN FBLN5 VWF TRIM67 KRTAP10-1 KRTAP10-9 KRTAP10-11	7.68e-06	417	36	7	int:NUFIP2
Interaction	ZNF438 interactions	SYT17 KRTAP10-1 KRT40 MYLIP	8.09e-06	72	36	4	int:ZNF438
Interaction	LCE2D interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11	9.02e-06	74	36	4	int:LCE2D
Interaction	WT1 interactions	EZH2 KRTAP10-1 KRTAP10-9 KRT40	1.00e-05	76	36	4	int:WT1
Interaction	SPATA3 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-11	1.03e-05	24	36	3	int:SPATA3
Interaction	LCE1C interactions	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.06e-05	77	36	4	int:LCE1C
Interaction	SMCP interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11	1.17e-05	79	36	4	int:SMCP
Interaction	LCE4A interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11	1.23e-05	80	36	4	int:LCE4A
Interaction	KRTAP4-4 interactions	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.29e-05	81	36	4	int:KRTAP4-4
Interaction	LCE2B interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11	1.29e-05	81	36	4	int:LCE2B
Interaction	SLC23A1 interactions	KRTAP10-1 KRTAP10-9 KRT40	1.32e-05	26	36	3	int:SLC23A1
Interaction	YY1 interactions	GRN TRIM67 EZH1 EZH2 KRTAP10-9 ZMYM3 MSL2	1.33e-05	454	36	7	int:YY1
Interaction	POU4F2 interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11	1.42e-05	83	36	4	int:POU4F2
Interaction	ZNF439 interactions	KRTAP10-1 KRTAP10-9 KRT40	1.49e-05	27	36	3	int:ZNF439
Interaction	LCE1A interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11	1.49e-05	84	36	4	int:LCE1A
Interaction	LCE5A interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11	1.96e-05	90	36	4	int:LCE5A
Interaction	ZNF286A interactions	KRTAP10-1 KRTAP10-9 KRT40	2.06e-05	30	36	3	int:ZNF286A
Interaction	LCE1F interactions	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	2.14e-05	92	36	4	int:LCE1F
Interaction	KRTAP4-11 interactions	KRTAP15-1 KRTAP10-1 KRTAP10-9 KRTAP10-11	2.14e-05	92	36	4	int:KRTAP4-11
Interaction	GLRX3 interactions	GRN TRIM67 KRTAP10-1 KRTAP10-9 KRTAP10-11	2.15e-05	191	36	5	int:GLRX3
Interaction	KRTAP5-6 interactions	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	2.33e-05	94	36	4	int:KRTAP5-6
Interaction	KRTAP5-9 interactions	GRN KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	2.89e-05	203	36	5	int:KRTAP5-9
Interaction	GNE interactions	GRN TRIM67 KRTAP10-9 KRT40	3.47e-05	104	36	4	int:GNE
Interaction	DIS3L2 interactions	TRIM67 EZH2 ZMYM3	4.58e-05	39	36	3	int:DIS3L2
Interaction	ZNF440 interactions	FBLN5 KRTAP10-1 KRTAP10-9	4.94e-05	40	36	3	int:ZNF440
Interaction	PRKAB2 interactions	RNF144B GRN KRTAP10-9 KRTAP10-11 KRT40	5.68e-05	234	36	5	int:PRKAB2
Interaction	KRTAP10-8 interactions	GRN KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	7.02e-05	401	36	6	int:KRTAP10-8
Interaction	CATSPER1 interactions	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	7.35e-05	126	36	4	int:CATSPER1
Interaction	AVPI1 interactions	KRTAP10-1 KRTAP10-9 KRT40	8.57e-05	48	36	3	int:AVPI1
Interaction	ZNF165 interactions	ZNF263 KRTAP10-9 KRT40	9.11e-05	49	36	3	int:ZNF165
Interaction	KRTAP9-3 interactions	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.11e-04	140	36	4	int:KRTAP9-3
Interaction	SPATA31J1 interactions	KRTAP10-9 KRT40	1.11e-04	9	36	2	int:SPATA31J1
Interaction	HTRA1 interactions	TRIM67 EZH2 MSMB	1.22e-04	54	36	3	int:HTRA1
Interaction	LINGO1 interactions	KRTAP10-1 NTRK3 MSMB	1.22e-04	54	36	3	int:LINGO1
Interaction	AHCYL2 interactions	ZNF263 GRN TRIM67 NTRK3	1.27e-04	145	36	4	int:AHCYL2
Interaction	FBXO34 interactions	KRTAP10-1 KRTAP10-11 KRT40	1.29e-04	55	36	3	int:FBXO34
Interaction	PRKAG1 interactions	TRIM67 KRTAP10-1 KRTAP10-11 NTRK3	1.33e-04	147	36	4	int:PRKAG1
Interaction	ZNF433 interactions	KRTAP10-1 KRTAP10-9	1.38e-04	10	36	2	int:ZNF433
Interaction	CCDC26 interactions	KRTAP10-9 KRT40	1.38e-04	10	36	2	int:CCDC26
Interaction	KRTAP9-2 interactions	KRTAP15-1 KRTAP10-1 KRTAP10-9 KRTAP10-11	1.41e-04	149	36	4	int:KRTAP9-2
Interaction	SPRY2 interactions	GRN KRTAP10-1 KRTAP10-9 KRTAP10-11	1.52e-04	152	36	4	int:SPRY2
Interaction	ZNF124 interactions	KRTAP10-1 KRTAP10-9 KRT40	1.59e-04	59	36	3	int:ZNF124
Interaction	FBXL18 interactions	TRIM67 EZH2 KRT40	1.67e-04	60	36	3	int:FBXL18
Interaction	SLTM interactions	ZNF263 TRIM67 EZH1 EZH2	1.68e-04	156	36	4	int:SLTM
Interaction	POM121L8P interactions	KRTAP10-1 KRT40	1.69e-04	11	36	2	int:POM121L8P
Interaction	KRTAP5-2 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-11	1.84e-04	62	36	3	int:KRTAP5-2
Interaction	ANKS1A interactions	RNF144B EZH2 KRTAP10-9 KRTAP10-11	1.94e-04	162	36	4	int:ANKS1A
Interaction	KRTAP10-11 interactions	KRTAP10-1 KRTAP10-9 KRTAP10-11	2.02e-04	64	36	3	int:KRTAP10-11
Interaction	GLIDR interactions	KRTAP10-9 KRT40	2.02e-04	12	36	2	int:GLIDR
Interaction	UBE2Z interactions	RNF144B TRIM67 RNF103	2.12e-04	65	36	3	int:UBE2Z
Interaction	KRTAP5-11 interactions	KRTAP15-1 KRTAP10-1 KRTAP10-9	2.22e-04	66	36	3	int:KRTAP5-11
Interaction	DOCK2 interactions	KRTAP10-1 KRTAP10-9 KRT40	2.22e-04	66	36	3	int:DOCK2
Interaction	KRTAP5-3 interactions	KRTAP15-1 KRTAP10-1 KRTAP10-9	2.22e-04	66	36	3	int:KRTAP5-3
Interaction	BAHD1 interactions	EZH2 KRTAP10-1 KRT40	2.32e-04	67	36	3	int:BAHD1
Interaction	WT1-AS interactions	KRTAP10-9 KRT40	2.39e-04	13	36	2	int:WT1-AS
Interaction	PHF1 interactions	TRIM67 EZH1 EZH2 KRT40	2.44e-04	172	36	4	int:PHF1
Interaction	LCE2A interactions	KRTAP10-1 KRTAP10-9 KRTAP10-11	2.53e-04	69	36	3	int:LCE2A
Interaction	CYSRT1 interactions	GRN KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	2.63e-04	511	36	6	int:CYSRT1
Interaction	ZGPAT interactions	TRIM67 EZH1 EZH2 KRT40	2.66e-04	176	36	4	int:ZGPAT
Interaction	NAXD interactions	NFXL1 TRIM67 KRTAP10-9	2.75e-04	71	36	3	int:NAXD
Interaction	PGLS interactions	TRIM67 KRTAP10-9 KRT40	2.75e-04	71	36	3	int:PGLS
Interaction	ZNF417 interactions	KRTAP10-1 KRTAP10-9 KRT40 MYLIP	2.78e-04	178	36	4	int:ZNF417
Interaction	ZNF844 interactions	KRTAP10-9 KRT40	2.79e-04	14	36	2	int:ZNF844
Interaction	SKIDA1 interactions	EZH1 EZH2	2.79e-04	14	36	2	int:SKIDA1
Interaction	GPATCH2L interactions	ZNF263 KRTAP10-9 KRT40	2.87e-04	72	36	3	int:GPATCH2L
Interaction	LCE3D interactions	KRTAP10-1 KRTAP10-9 KRTAP10-11	2.99e-04	73	36	3	int:LCE3D
Interaction	CHIC2 interactions	KRTAP10-1 KRTAP10-9 KRT40	2.99e-04	73	36	3	int:CHIC2
Interaction	MAPKBP1 interactions	KRTAP10-1 KRTAP10-9 KRT40	3.11e-04	74	36	3	int:MAPKBP1
Interaction	C10orf62 interactions	KRTAP10-9 KRT40	3.21e-04	15	36	2	int:C10orf62
Interaction	LCE3A interactions	KRTAP10-1 KRTAP10-9 KRTAP10-11	3.36e-04	76	36	3	int:LCE3A
Interaction	KLHDC2 interactions	FBLN5 EZH2 UBE3D	3.36e-04	76	36	3	int:KLHDC2
Interaction	KRT6C interactions	TRIM67 EZH2 KRT40	3.36e-04	76	36	3	int:KRT6C
Interaction	RAPGEF6 interactions	GRN TRIM67 NTRK3	3.63e-04	78	36	3	int:RAPGEF6
Interaction	WWC3 interactions	TRIM67 EZH2	3.66e-04	16	36	2	int:WWC3
Interaction	UBE2N interactions	TRIM67 EZH2 RNF103 NTRK3 MYLIP	3.77e-04	351	36	5	int:UBE2N
Interaction	TMSB4X interactions	TRIM67 EZH2 KRT40	3.91e-04	80	36	3	int:TMSB4X
Interaction	SAFB2 interactions	ZNF263 TRIM67 EZH1 EZH2	3.93e-04	195	36	4	int:SAFB2
Interaction	ZNF512B interactions	GRN VWF TRIM67 EZH2	4.01e-04	196	36	4	int:ZNF512B
Interaction	CATIP interactions	KRTAP10-9 KRT40	4.15e-04	17	36	2	int:CATIP
Interaction	WASH6P interactions	TRIM67 NTRK3	4.15e-04	17	36	2	int:WASH6P
Cytoband	Ensembl 112 genes in cytogenetic band chr21q22	KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 DOP1B	5.53e-07	377	37	6	chr21q22
Cytoband	21q22.3	KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	3.55e-06	128	37	4	21q22.3
Cytoband	17q21.2	KRTAP29-1 KRTAP16-1 KRT40	2.54e-05	70	37	3	17q21.2
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	KRTAP29-1 GRN EZH1 KRTAP16-1 KRT40	3.78e-05	473	37	5	chr17q21
Cytoband	Xq25	TENM1 RAP2C	5.08e-04	41	37	2	Xq25
Cytoband	Ensembl 112 genes in cytogenetic band chr6p22	RNF144B MYLIP ZFP57	3.50e-03	378	37	3	chr6p22
Cytoband	11p15.5	MUC5B MUC2	4.11e-03	118	37	2	11p15.5
GeneFamily	Keratin associated proteins	KRTAP29-1 KRTAP16-1 KRTAP15-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11	3.33e-10	109	29	7	619
GeneFamily	CD molecules\|Mucins	MUC19 MUC5B MUC2	4.84e-06	21	29	3	648
GeneFamily	Lysine methyltransferases\|Myb/SANT domain containing\|Polycomb repressive complex 2	EZH1 EZH2	3.71e-05	6	29	2	1347
GeneFamily	Ring finger proteins	RNF144B TRIM67 RNF103 MSL2	9.22e-04	275	29	4	58
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	EZH1 EZH2	1.35e-03	34	29	2	487
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	EZH1 EZH2	3.25e-03	53	29	2	532
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	KRTAP29-1 KRTAP16-1 KRTAP10-10 KRTAP10-1 KRTAP10-9 KRTAP10-11 KRT40	3.11e-11	146	37	7	522c32103c24fc26836bb5b642083904682d9292
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN5 VWF DOP1B ZFP57	1.13e-05	168	37	4	32e4d82efaccf336d347e4063253c3635a3ec672
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN5 VWF TRIM67 RNF103	1.26e-05	173	37	4	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	distal-1-Endothelial-Artery\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RNF144B FBLN5 VWF MYLIP	2.19e-05	199	37	4	fd71d08f6de790a29c880d50d2ed0881952d7791
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RNF144B MUC5B DOP1B MSMB	2.23e-05	200	37	4	c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cadm2_(Cadm2_state)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	LRTM1 TRIM67 UBE3D	4.34e-05	82	37	3	01a4d47d9e0dee68a5277ed1534338cec80f75d1
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cadm2_(Cadm2_state)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	LRTM1 TRIM67 UBE3D	4.34e-05	82	37	3	c1489097c291f413f3cfa5e26f8182ec872328fd
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col18a1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTS3 SYT17 ZFP57	2.50e-04	148	37	3	fc80c02b51cf55a04ce550838ee2f41d8f656f41
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRTM1 MUC19 MUC5B	3.14e-04	160	37	3	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRTM1 MUC19 MUC5B	3.14e-04	160	37	3	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MUC19 FBLN5 VWF	3.25e-04	162	37	3	25bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MSMB ZFP57	3.62e-04	168	37	3	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MSMB ZFP57	3.62e-04	168	37	3	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	Club_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	MUC5B KRT40 MSMB	3.68e-04	169	37	3	03b303af8a26c6ff196507fe24f5bd3d75d7b1af
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 VWF ZFP57	3.75e-04	170	37	3	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 VWF ZFP57	3.75e-04	170	37	3	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 VWF ZFP57	3.75e-04	170	37	3	3232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN5 VWF MUC2	3.75e-04	170	37	3	af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B MUC2 DOP1B	3.81e-04	171	37	3	48125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN5 VWF MUC2	3.88e-04	172	37	3	9a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRTM1 KRT40 MSMB	3.94e-04	173	37	3	30fa8c14c8a1f546f380132c0c28a61e6a2f9fc4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	4.15e-04	176	37	3	682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MUC19 FBLN5 VWF	4.22e-04	177	37	3	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF144B FBLN5 VWF	4.29e-04	178	37	3	5cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MUC19 RNF144B VWF	4.29e-04	178	37	3	c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCell	facs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF144B FBLN5 VWF	4.29e-04	178	37	3	f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RNF144B FBLN5 VWF	4.36e-04	179	37	3	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	4.43e-04	180	37	3	8f774dcacc1626e4e6492f1eb927b0ed56fbe686
ToppCell	(5)_Epithelial_cells-(5)_Glands_mucous\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	MUC5B FBLN5 MSMB	4.43e-04	180	37	3	a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCell	Ciliated_cells-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	MUC5B KRT40 MSMB	4.43e-04	180	37	3	d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRTM1 ADAMTS3 NTRK3	4.43e-04	180	37	3	d67d3196e6cc3dcd31023a4dc69310226181d583
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRTM1 ADAMTS3 NTRK3	4.43e-04	180	37	3	573308d43425d9fba20787abdb7f8efefc48efb5
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RNF144B FBLN5 VWF	4.50e-04	181	37	3	72c28baf4fd417ff4a7068603830d55074960144
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RNF144B FBLN5 VWF	4.50e-04	181	37	3	2ac4d3e8987d5a009d7908d8787e18165826202a
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RNF144B FBLN5 VWF	4.50e-04	181	37	3	2628c7ac345eaaeecf8e34617e81948925962cb9
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B MUC2	4.57e-04	182	37	3	08aff7112c9dac0ef5540300516a604782b21169
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNF144B GRN VWF	4.65e-04	183	37	3	36b194e366a14ebc4df187bf31c902be3797bfcc
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	4.65e-04	183	37	3	121791ef84e7ce377ed6f5b7953af8865e04958e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	4.65e-04	183	37	3	04d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B KRT40 MSMB	4.65e-04	183	37	3	263937906ddabc798bbe60f0da28ba859a5c72e2
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	4.72e-04	184	37	3	1158a55c1990fd23d270cb6510d0951c4bfcddc5
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MUC19 RNF144B VWF	4.72e-04	184	37	3	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	4.72e-04	184	37	3	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM1 FBLN5 ADAMTS3	4.79e-04	185	37	3	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|metastatic_Brain / Location, Cell class and cell subclass	RNF144B FBLN5 VWF	4.79e-04	185	37	3	ad52970e88e8947ef256095bd4b40229b912d58a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	4.87e-04	186	37	3	948815663c212c4311329d503b5991cbbbff9808
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	4.87e-04	186	37	3	96f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	RNF144B FBLN5 VWF	4.95e-04	187	37	3	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	4.95e-04	187	37	3	85f1678338a47d91e296f0620d4887f057eb7e70
ToppCell	SMG-Goblet\|World / shred by cell class for bronchial biopsy	MUC19 MUC5B MSMB	4.95e-04	187	37	3	5178118bdec91495253c88f58fd908cf831de7ef
ToppCell	normal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ\|B_lymphocytes / Location, Cell class and cell subclass	RNF144B EZH2 SYT17	4.95e-04	187	37	3	457eb3791a8c5458d81833e0701ac5a9bfdee2bf
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.02e-04	188	37	3	72cbfe9dc0583dbeafa6cb0945fa370d0c808284
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MUC19 RNF144B VWF	5.02e-04	188	37	3	b66f1f08827dd6c48583d871f9f33ea41e48bfb2
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.02e-04	188	37	3	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.10e-04	189	37	3	78cf414b98bcb19deb934409acddaad1cd51b67f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.18e-04	190	37	3	26843ec1d19ac85a50990705353b802745d33e4d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.18e-04	190	37	3	3f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.18e-04	190	37	3	d19bc44310c53726e2f5f6a2bd377bbbf1d1983f
ToppCell	facs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRTM1 TRIM67 NTRK3	5.18e-04	190	37	3	c7bd087f36321cec61b98657433b4d19d135791f
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MUC19 RNF144B VWF	5.18e-04	190	37	3	1307688255a1250fa300edf2c41f1affe31dcc98
ToppCell	15-Distal-Mesenchymal-Mesenchyme_SERPINF1-high\|Distal / Age, Tissue, Lineage and Cell class	LRTM1 FBLN5 NTRK3	5.18e-04	190	37	3	b47472dc9fe6ed99c2365203a3d8a59879e74a70
ToppCell	facs-Lung-nan-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRTM1 TRIM67 NTRK3	5.18e-04	190	37	3	834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.18e-04	190	37	3	0acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.18e-04	190	37	3	e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	RNF144B FBLN5 VWF	5.26e-04	191	37	3	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRTM1 TRIM67 NTRK3	5.26e-04	191	37	3	fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Npnt_(Retrosplenial_areas,_layer_5,_Npnt+)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	LRTM1 TMCO2	5.29e-04	41	37	2	b1e70962de91a747ec718a3fad4247fd0cb7d9a8
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Npnt_(Retrosplenial_areas,_layer_5,_Npnt+)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	LRTM1 TMCO2	5.29e-04	41	37	2	16dbb13baa47c4db80ddd83ac36aad6c43b5461a
ToppCell	ASK428-Endothelial-Endothelium\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	RNF144B VWF	5.29e-04	41	37	2	a72d926de3dc9e420b80764af88002e436517790
ToppCell	IPF-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	RNF144B FBLN5 MYLIP	5.34e-04	192	37	3	e911e286da26202853f9650ba3cdefe5a5c9b585
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	RNF144B FBLN5 VWF	5.34e-04	192	37	3	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.42e-04	193	37	3	53bcd50892c379b2a571751f6eb1062436339fe7
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.42e-04	193	37	3	d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.42e-04	193	37	3	4979862c0c16e6b4baa4c79894f1d237c861f5a5
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B MUC2 DOP1B	5.42e-04	193	37	3	402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.42e-04	193	37	3	010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.42e-04	193	37	3	3ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.42e-04	193	37	3	2189da4b727e25e62669d7b9257f06493be21a27
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.42e-04	193	37	3	658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.42e-04	193	37	3	5581a5ebcd21a2a8062ccfb917f088ec67a10a9c
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNF144B GRN DAGLA	5.42e-04	193	37	3	00c9c2945d2bdaa128e054cf3c59df86a279b659
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B MUC2 DOP1B	5.42e-04	193	37	3	7ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.51e-04	194	37	3	e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 ADAMTS3 NTRK3	5.51e-04	194	37	3	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 VWF ZFP57	5.51e-04	194	37	3	e8102c8811333f04de7280b7d9b6b85cebb815ac
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.51e-04	194	37	3	02a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 VWF ZFP57	5.51e-04	194	37	3	4b0d63babb8a46ff45731d5f82b29ccaf6c9402d
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRTM1 TRIM67 NTRK3	5.59e-04	195	37	3	c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN5 ADAMTS3 NTRK3	5.59e-04	195	37	3	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRTM1 TRIM67 NTRK3	5.59e-04	195	37	3	ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B MUC2 DOP1B	5.59e-04	195	37	3	09605533aa5947bb2e5a6725c1ce89f79d330bf5
ToppCell	10x5'-blood-Myeloid_Monocytic-Nonclassical_monocytes\|blood / Manually curated celltypes from each tissue	RNF144B GRN SYT17	5.59e-04	195	37	3	88d65c7c3a28922c125bd9f7c403a55d7d4d83a9
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B MUC2 DOP1B	5.59e-04	195	37	3	7ff04c45a02df01e3816f3c1d43585a93182a730
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM1 RNF144B TRIM67	5.67e-04	196	37	3	7af6c5147ac859353504d19727dbe24f63a29dd4
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B MUC2 DOP1B	5.67e-04	196	37	3	847b3377f463bfded046eec63cc1b547f3dc33c1
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LRTM1 SYT17 ZFP57	5.67e-04	196	37	3	50aaca81b593ff71790bb75403b2e4c3ab03a6d2
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B MUC2 DOP1B	5.76e-04	197	37	3	d624f3a105b19f19a0dd253ce8de3ed13adc1f01
ToppCell	distal-Epithelial-Goblet\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MUC5B MUC2 MSMB	5.76e-04	197	37	3	da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCell	distal-3-Epithelial-Goblet\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MUC5B MUC2 MSMB	5.76e-04	197	37	3	a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCell	distal-Epithelial-Goblet-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MUC5B MUC2 MSMB	5.76e-04	197	37	3	3fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
Computational	Genes in the cancer module 204.	ZNF263 EZH2 DOP1B	4.37e-04	86	19	3	MODULE_204
Computational	Trachea genes.	GRN MUC5B VWF ZMYM3 MSMB	6.22e-04	415	19	5	MODULE_6
Drug	7-heptacosene	EZH1 EZH2	6.88e-06	3	35	2	CID006430696
Disease	bipolar disorder (is_marker_for)	GRN VWF	1.69e-04	19	30	2	DOID:3312 (is_marker_for)
Disease	invasive ductal carcinoma (is_marker_for)	EZH2 NTRK3	7.61e-04	40	30	2	DOID:3008 (is_marker_for)
Disease	Endometrial Neoplasms	RNF144B EZH2	1.59e-03	58	30	2	C0014170
Disease	irritable bowel syndrome symptom measurement	TRIM67 DOP1B	1.59e-03	58	30	2	EFO_0021536
Disease	pancreatic ductal carcinoma (is_marker_for)	MUC5B NTRK3	1.76e-03	61	30	2	DOID:3587 (is_marker_for)
Disease	cystic fibrosis (is_marker_for)	MUC5B MUC2	1.82e-03	62	30	2	DOID:1485 (is_marker_for)
Disease	cholangiocarcinoma (is_marker_for)	MUC5B MUC2	1.94e-03	64	30	2	DOID:4947 (is_marker_for)
Disease	stomach cancer (is_implicated_in)	EZH2 NTRK3	2.44e-03	72	30	2	DOID:10534 (is_implicated_in)
Disease	Endometrial Carcinoma	RNF144B EZH2	2.44e-03	72	30	2	C0476089
Disease	lung cancer (is_implicated_in)	EZH2 DAGLA	2.58e-03	74	30	2	DOID:1324 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
CCPAGYTCNVKARSC	GRN	481	P28799
KTGCCYSCEEDSCQV	MUC5B	5646	Q9HC84
YSSLPEKQDQCCTTC	RAP2C	166	Q9Y3L5
QECQCIFCTACLKQY	RNF144B	46	Q7Z419
EPCSAYVICTVENCC	KRT40	416	Q6A162
QVVCSCPDKCYCQSS	LRTM1	16	Q9HBL6
CPDKCYCQSSTNFVD	LRTM1	21	Q9HBL6
SCYPCPETVDVKCNC	NFXL1	516	Q6ZNB6
ACPANCVCSKTEINC	NTRK3	31	Q16288
CCCVTDCYLQNVAIS	DOP1B	801	Q9Y3R5
CVIAQNFCEKFCQCS	EZH2	536	Q15910
YTCTCENSQDCLCTI	MUC19	1036	Q7Z5P9
CLNYEINVQCCECVT	MUC2	1866	Q02817
VCCESCAAQLQSCPV	MYLIP	406	Q8WY64
NCETCTCYETEISCC	MSMB	56	P08118
APTNSTCQHYVCKTC	MSL2	56	Q9HCI7
YCSIPGYNKLCCESC	ADAMTS3	1036	O15072
QCCCCEQEEPTYFAI	DAGLA	616	Q9Y4D2
CYVPTCSEDSSSCCQ	KRTAP10-1	151	P60331
TPSCCQQSSCQPAYC	KRTAP10-9	76	P60411
QPAYCTSSPCQQACC	KRTAP10-9	86	P60411
CKPVCCAPTCSEDSY	KRTAP10-9	146	P60411
CAPTCSEDSYSCCQQ	KRTAP10-9	151	P60411
TTPCYQQSSCQPDCC	KRTAP10-10	71	P60014
PACCTSSSYQQACCV	KRTAP10-11	176	P60412
SSSYQQACCVPVCCK	KRTAP10-11	181	P60412
QACCVPVCCKTVYCK	KRTAP10-11	186	P60412
CQETYCEPTSCQTSC	KRTAP15-1	51	Q3LI76
SNCCQPVCFEATVCE	KRTAP16-1	126	A8MUX0
PSYNQSGCKSACCVT	KRTAP29-1	296	A8MX34
CATENPCVQTCVNTY	FBLN5	211	Q9UBX5
CSCANKYCQTSPCER	RNF103	576	O00237
RDCSSEPYCSCSDCQ	TMCO2	156	Q7Z6W1
CQKCYESSCCQSSED	SYT17	31	Q9BSW7
DCVDPDCCQQSNCYI	TENM1	816	Q9UKZ4
DCCQQSNCYISPLCQ	TENM1	821	Q9UKZ4
TLCEQCDVLYCSACQ	TRIM67	221	Q6ZTA4
PFCCTLCDKTYCDAS	ZFP57	146	Q9NU63
EYECACNCVNSTVSC	VWF	2391	P04275
CCTFYCQSCGEVIIK	UBE3D	106	Q7Z6J8
CRCKTQCNTKQCPCY	EZH1	561	Q92800
KLGLCCITCTYCSQT	ZMYM3	671	Q14202
IQCQTCSKSHCSCPQ	ZAR1L	271	A6NP61
PYQCNICGKCFSCNS	ZNF263	461	O14978