Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	FAT1 NAALADL1 GUCA1C HMCN2 PCDHGB7 CADPS NINL DYSF PCDHB1 ITIH1 NCS1 C2CD5 MICU1	5.37e-05	749	95	13	GO:0005509
GeneOntologyMolecularFunction	myosin V binding	RAB3D RAB3B RAB3C	1.12e-04	20	95	3	GO:0031489
GeneOntologyMolecularFunction	nucleoside:sodium symporter activity	SLC28A2 SLC28A1	1.34e-04	4	95	2	GO:0005415
GeneOntologyMolecularFunction	nucleobase:monoatomic cation symporter activity	SLC28A2 SLC28A1	1.34e-04	4	95	2	GO:0015391
GeneOntologyMolecularFunction	pyrimidine- and adenosine-specific:sodium symporter activity	SLC28A2 SLC28A1	1.34e-04	4	95	2	GO:0015389
GeneOntologyMolecularFunction	GTP-dependent protein binding	RAB3D RAB3B RAB3C	1.96e-04	24	95	3	GO:0030742
GeneOntologyMolecularFunction	uridine transmembrane transporter activity	SLC28A2 SLC28A1	3.32e-04	6	95	2	GO:0015213
GeneOntologyMolecularFunction	calcium sensitive guanylate cyclase activator activity	GUCA1C NCS1	3.32e-04	6	95	2	GO:0008048
GeneOntologyMolecularFunction	pyrimidine nucleobase transmembrane transporter activity	SLC28A2 SLC28A1	4.63e-04	7	95	2	GO:0005350
GeneOntologyMolecularFunction	protein phosphatase 1 binding	PPP1R3A PPP1CA PPP1CC	6.11e-04	35	95	3	GO:0008157
GeneOntologyMolecularFunction	guanylate cyclase activator activity	GUCA1C NCS1	6.16e-04	8	95	2	GO:0030250
GeneOntologyMolecularFunction	pyrimidine nucleoside transmembrane transporter activity	SLC28A2 SLC28A1	6.16e-04	8	95	2	GO:0015214
GeneOntologyMolecularFunction	guanylate cyclase regulator activity	GUCA1C NCS1	7.89e-04	9	95	2	GO:0030249
GeneOntologyMolecularFunction	purine nucleobase transmembrane transporter activity	SLC28A2 SLC28A1	9.83e-04	10	95	2	GO:0005345
GeneOntologyMolecularFunction	nucleoside transmembrane transporter activity	SLC28A2 SLC28A1	9.83e-04	10	95	2	GO:0005337
GeneOntologyMolecularFunction	nucleobase transmembrane transporter activity	SLC28A2 SLC28A1	1.20e-03	11	95	2	GO:0015205
GeneOntologyMolecularFunction	axon guidance receptor activity	EPHB2 HMCN2	1.69e-03	13	95	2	GO:0008046
GeneOntologyMolecularFunction	cyclase activator activity	GUCA1C NCS1	1.69e-03	13	95	2	GO:0010853
GeneOntologyMolecularFunction	azole transmembrane transporter activity	SLC28A2 SLC28A1	1.96e-03	14	95	2	GO:1901474
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC11A2 SLC20A1 SLC28A2 SLC28A1	2.51e-03	119	95	4	GO:0015294
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO2 NOMO3 NOMO1	7.79e-06	9	95	3	GO:0160063
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO2 NOMO3 NOMO1	7.49e-06	9	95	3	GO:0160064
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO2 NOMO3 NOMO1	3.19e-05	14	95	3	GO:0072379
GeneOntologyCellularComponent	presynapse	EPHB2 EFNB1 ADAM23 CADPS GLRA3 RAB3D DYSF RAB3B DENND1A RAB3C NCS1 HTT PPP1CA PPP1CC	4.57e-05	886	95	14	GO:0098793
GeneOntologyCellularComponent	protein phosphatase type 1 complex	PPP1R3A PPP1CA PPP1CC	8.36e-05	19	95	3	GO:0000164
GeneOntologyCellularComponent	PTW/PP1 phosphatase complex	PPP1CA PPP1CC	4.23e-04	7	95	2	GO:0072357
Domain	DUF2012	NOMO2 NOMO3 NOMO1	5.08e-07	4	95	3	PF09430
Domain	DUF2012	NOMO2 NOMO3 NOMO1	5.08e-07	4	95	3	IPR019008
Domain	Carb-bd-like_fold	NOMO2 NOMO3 NOMO1	7.01e-06	8	95	3	IPR013784
Domain	CarboxyPept_regulatory_dom	NOMO2 NOMO3 NOMO1	3.51e-05	13	95	3	IPR014766
Domain	-	NOMO2 NOMO3 NOMO1	3.51e-05	13	95	3	2.60.40.1120
Domain	CNT_N_dom	SLC28A2 SLC28A1	7.65e-05	3	95	2	IPR002668
Domain	C_nuclsd_transpt	SLC28A2 SLC28A1	7.65e-05	3	95	2	IPR008276
Domain	CNT_C_dom	SLC28A2 SLC28A1	7.65e-05	3	95	2	IPR011657
Domain	C_nuclsd_transpt_met_bac	SLC28A2 SLC28A1	7.65e-05	3	95	2	IPR018270
Domain	Gate_dom	SLC28A2 SLC28A1	7.65e-05	3	95	2	IPR011642
Domain	Nucleos_tra2_N	SLC28A2 SLC28A1	7.65e-05	3	95	2	PF01773
Domain	STPPase_N	PPP1CA PPP1CC	7.65e-05	3	95	2	IPR031675
Domain	STPPase_N	PPP1CA PPP1CC	7.65e-05	3	95	2	PF16891
Domain	Nucleos_tra2_C	SLC28A2 SLC28A1	7.65e-05	3	95	2	PF07662
Domain	Gate	SLC28A2 SLC28A1	7.65e-05	3	95	2	PF07670
Domain	CarboxyPept-like_regulatory	NOMO2 NOMO3 NOMO1	8.23e-05	17	95	3	IPR008969
Domain	MARK/par1	MARK1 MARK3	1.53e-04	4	95	2	IPR033624
Domain	KA1_dom	MARK1 MARK3	2.53e-04	5	95	2	IPR001772
Domain	KA1	MARK1 MARK3	2.53e-04	5	95	2	PF02149
Domain	KA1	MARK1 MARK3	2.53e-04	5	95	2	PS50032
Domain	-	MARK1 MARK3	2.53e-04	5	95	2	3.30.310.80
Domain	CH	LMO7 MICAL2 SYNE2 MICAL3	3.35e-04	65	95	4	SM00033
Domain	FAD-bd	MICAL2 MICAL3	3.79e-04	6	95	2	IPR002938
Domain	FAD_binding_3	MICAL2 MICAL3	3.79e-04	6	95	2	PF01494
Domain	CH	LMO7 MICAL2 SYNE2 MICAL3	4.45e-04	70	95	4	PF00307
Domain	UBA	VPS13D MARK1 MARK3	4.69e-04	30	95	3	SM00165
Domain	-	LMO7 MICAL2 SYNE2 MICAL3	4.70e-04	71	95	4	1.10.418.10
Domain	CH	LMO7 MICAL2 SYNE2 MICAL3	5.23e-04	73	95	4	PS50021
Domain	KA1/Ssp2_C	MARK1 MARK3	5.29e-04	7	95	2	IPR028375
Domain	CH-domain	LMO7 MICAL2 SYNE2 MICAL3	5.79e-04	75	95	4	IPR001715
Domain	UBA	VPS13D MARK1 MARK3	8.06e-04	36	95	3	PF00627
Domain	UBA	VPS13D MARK1 MARK3	1.45e-03	44	95	3	IPR015940
Domain	UBA	VPS13D MARK1 MARK3	1.76e-03	47	95	3	PS50030
Domain	Ser/Thr-sp_prot-phosphatase	PPP1CA PPP1CC	1.93e-03	13	95	2	IPR006186
Domain	SER_THR_PHOSPHATASE	PPP1CA PPP1CC	1.93e-03	13	95	2	PS00125
Domain	PP2Ac	PPP1CA PPP1CC	1.93e-03	13	95	2	SM00156
Domain	Recoverin	GUCA1C NCS1	1.93e-03	13	95	2	IPR028846
Domain	Pept_M10A_stromelysin-type	MMP25 MMP17	3.71e-03	18	95	2	IPR016293
Domain	P-loop_NTPase	ARHGAP5 PALS1 TRANK1 KIF27 RRAGD DHX40 DDX60 RAB3D RAB3B HYDIN RAB3C	3.82e-03	848	95	11	IPR027417
Domain	RRM_1	HNRNPDL SPEN RBM39 HNRNPH3 LARP7	4.21e-03	208	95	5	PF00076
Domain	PG_binding_1	MMP25 MMP17	4.58e-03	20	95	2	PF01471
Domain	Peptidoglycan-bd-like	MMP25 MMP17	4.58e-03	20	95	2	IPR002477
Domain	-	ARHGAP5 PALS1 TRANK1 RRAGD DHX40 DDX60 RAB3D RAB3B HYDIN RAB3C	4.62e-03	746	95	10	3.40.50.300
Domain	RRM	HNRNPDL SPEN RBM39 HNRNPH3 LARP7	5.03e-03	217	95	5	SM00360
Domain	Ras	ARHGAP5 RAB3D RAB3B RAB3C	5.14e-03	136	95	4	PF00071
Domain	LIM	LMO7 MICAL2 MICAL3	5.24e-03	69	95	3	PF00412
Domain	-	LMO7 MICAL2 MICAL3	5.46e-03	70	95	3	2.10.110.10
Domain	Znf_LIM	LMO7 MICAL2 MICAL3	5.68e-03	71	95	3	IPR001781
Domain	LIM_DOMAIN_1	LMO7 MICAL2 MICAL3	5.68e-03	71	95	3	PS00478
Domain	LIM_DOMAIN_2	LMO7 MICAL2 MICAL3	5.68e-03	71	95	3	PS50023
Domain	LIM	LMO7 MICAL2 MICAL3	5.68e-03	71	95	3	SM00132
Domain	Hemopexin-like_dom	MMP25 MMP17	6.04e-03	23	95	2	IPR000585
Domain	Hemopexin-like_repeat	MMP25 MMP17	6.04e-03	23	95	2	IPR018487
Domain	M10A_MMP	MMP25 MMP17	6.04e-03	23	95	2	IPR033739
Domain	Hemopexin	MMP25 MMP17	6.04e-03	23	95	2	PF00045
Domain	HEMOPEXIN	MMP25 MMP17	6.04e-03	23	95	2	PS00024
Domain	-	MMP25 MMP17	6.04e-03	23	95	2	2.110.10.10
Domain	HEMOPEXIN_2	MMP25 MMP17	6.04e-03	23	95	2	PS51642
Domain	HX	MMP25 MMP17	6.04e-03	23	95	2	SM00120
Domain	Pept_M10A	MMP25 MMP17	6.04e-03	23	95	2	IPR021190
Domain	RRM_dom	HNRNPDL SPEN RBM39 HNRNPH3 LARP7	6.07e-03	227	95	5	IPR000504
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	PALS1 EDC3 AKAP9 LMO7 MARK1 MARK3 NINL SH3GLB2 FRYL ECH1 DENND1A C2CD5 PPP1CA	3.28e-10	446	96	13	24255178
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO2 NOMO3 NOMO1	2.04e-08	3	96	3	36011023
Pubmed	Discovery of a Role for Rab3b in Habituation and Cocaine Induced Locomotor Activation in Mice Using Heterogeneous Functional Genomic Analysis.	RAB3D RAB3B RAB3C	2.04e-08	3	96	3	32742255
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO2 NOMO3 NOMO1	2.04e-08	3	96	3	25576386
Pubmed	Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion.	RAB3D RAB3B RAB3C	8.14e-08	4	96	3	12167638
Pubmed	Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells.	RAB3D RAB3B RAB3C	8.14e-08	4	96	3	20716109
Pubmed	A complete genetic analysis of neuronal Rab3 function.	RAB3D RAB3B RAB3C	8.14e-08	4	96	3	15269275
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO2 NOMO3 NOMO1	8.14e-08	4	96	3	31833031
Pubmed	Rab3 superprimes synaptic vesicles for release: implications for short-term synaptic plasticity.	RAB3D RAB3B RAB3C	8.14e-08	4	96	3	16436611
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO2 NOMO3 NOMO1	8.14e-08	4	96	3	9267806
Pubmed	Tctex-1, a novel interaction partner of Rab3D, is required for osteoclastic bone resorption.	RAB3D RAB3B RAB3C	2.03e-07	5	96	3	21262767
Pubmed	Rab3a is involved in transport of synaptic vesicles to the active zone in mouse brain nerve terminals.	RAB3D RAB3B RAB3C	2.03e-07	5	96	3	11598194
Pubmed	Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells.	RAB3D RAB3B RAB3C	2.03e-07	5	96	3	15159548
Pubmed	The interaction of PP1 with BRCA1 and analysis of their expression in breast tumors.	PPP1R3A PPP1CA PPP1CC	2.03e-07	5	96	3	17511879
Pubmed	The RAB3-RIM Pathway Is Essential for the Release of Neuromodulators.	RAB3D RAB3B RAB3C	4.05e-07	6	96	3	31679900
Pubmed	Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules.	RAB3D RAB3B RAB3C	4.05e-07	6	96	3	12192047
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	HNRNPDL SPATS2L OSBPL3 SPEN RBM39 HNRNPH3 PPP1CA PPP1CC	6.21e-07	258	96	8	37794589
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ARHGAP5 EDC3 NOMO2 OSBPL3 DHX40 NINL MICAL3 ECH1 PC RAB3B RBM39 HNRNPH3 FHIP2B	6.57e-07	853	96	13	28718761
Pubmed	Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.	RAB3D RAB3B RAB3C	7.08e-07	7	96	3	35871249
Pubmed	Mono-ubiquitination of Rabphilin 3A by UBE3A serves a non-degradative function.	RAB3D RAB3B RAB3C	7.08e-07	7	96	3	33542309
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	ARHGAP5 EXOSC10 SPATS2L TXNDC5 AKAP9 IPO7 RRAGD LMO7 MARK3 OSBPL3 RPS19BP1 ECH1 PC DENND1A LARP7 PPP1CC	1.06e-06	1371	96	16	36244648
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO2 NOMO3 NOMO1	1.13e-06	8	96	3	15257293
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	HNRNPDL ARHGAP5 EXOSC10 ERCC4 EDC3 RRAGD MARK1 PIK3CD SLC20A1 OSBPL3 RAB3D FRYL C2CD5 FHIP2B	1.67e-06	1084	96	14	11544199
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO2 NOMO3 NOMO1	1.69e-06	9	96	3	36261522
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	HNRNPDL PALS1 EXOSC10 SPATS2L IPO7 LMO7 MARK3 DDX60 PNO1 SPEN RBM39 HNRNPH3 PPP1CA PPP1CC MICU1	1.82e-06	1257	96	15	36526897
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	EXOSC10 EFNB1 TXNDC5 AKAP9 IPO7 NOMO2 MARK3 SLC20A1 SYNE2 DNAJB7 ECH1 LARP7 C2CD5 NOMO1 PPP1CC MICU1	3.01e-06	1487	96	16	33957083
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO2 NOMO3 NOMO1	3.31e-06	11	96	3	32820719
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	HNRNPDL EXOSC10 RO60 RBM39 HNRNPH3 LARP7 PPP1CC	5.38e-06	244	96	7	29884807
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	VPS13D NOMO2 TTC27 RO60 PC NOMO3 HNRNPH3 PPP1CA NOMO1 PPP1CC	7.05e-06	606	96	10	36538041
Pubmed	Identification and characterization of multiple novel Rab-myosin Va interactions.	RAB3D RAB3B RAB3C	7.26e-06	14	96	3	24006491
Pubmed	Cell segregation and border sharpening by Eph receptor-ephrin-mediated heterotypic repulsion.	EPHB2 EFNB1	7.54e-06	2	96	2	28747399
Pubmed	Mutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytes.	MYRF HTT	7.54e-06	2	96	2	25789755
Pubmed	Complementary expression and repulsive signaling suggest that EphB2 and ephrin-B1 are possibly involved in epithelial boundary formation at the squamocolumnar junction in the rodent stomach.	EPHB2 EFNB1	7.54e-06	2	96	2	23881165
Pubmed	EphB2 tyrosine kinase-dependent forward signaling in migration of neuronal progenitors that populate and form a distinct region of the dentate niche.	EPHB2 EFNB1	7.54e-06	2	96	2	21832177
Pubmed	In silico discovery and experimental validation of new protein-protein interactions.	DYSF HTT	7.54e-06	2	96	2	21280221
Pubmed	EphB-ephrinB bi-directional endocytosis terminates adhesion allowing contact mediated repulsion.	EPHB2 EFNB1	7.54e-06	2	96	2	12973358
Pubmed	Trans-synaptic Eph receptor-ephrin signaling in hippocampal mossy fiber LTP.	EPHB2 EFNB1	7.54e-06	2	96	2	12052960
Pubmed	Elevated Plasma Levels of MT4-MMP and MT6-MMP; A New Observation in Patients with Thyroid Nodules.	MMP25 MMP17	7.54e-06	2	96	2	38310435
Pubmed	PP-1α and PP-1γ display antagonism and differential roles in tumorigenicity of lung cancer cells.	PPP1CA PPP1CC	7.54e-06	2	96	2	23176181
Pubmed	Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2.	SLC28A2 SLC28A1	7.54e-06	2	96	2	10455109
Pubmed	Transgenic overexpression of ephrin b1 in bone cells promotes bone formation and an anabolic response to mechanical loading in mice.	EPHB2 EFNB1	7.54e-06	2	96	2	23874863
Pubmed	Stimulation of EphB2/ephrin-B1 signalling by tumour necrosis factor alpha in human dental pulp stem cells.	EPHB2 EFNB1	7.54e-06	2	96	2	25643922
Pubmed	Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1cgamma gene.	PPP1CA PPP1CC	7.54e-06	2	96	2	9882500
Pubmed	Transcription factors involved in the expression of SLC28 genes in human liver parenchymal cells.	SLC28A2 SLC28A1	7.54e-06	2	96	2	17187757
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	PALS1 TXNDC5 AKAP9 IPO7 LMO7 MARK3 MICAL2 PNO1 TTC27 RBM39 HNRNPH3 LARP7 PPP1CA PPP1CC	8.32e-06	1247	96	14	27684187
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	EDC3 LMO7 MARK1 MARK3 OSBPL3	9.72e-06	102	96	5	15778465
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PLXNA3 FAT1 PIK3CD NINL MICAL3 FRYL DYSF PC SPEN MMP17 MYRF DENND1A HTT	1.10e-05	1105	96	13	35748872
Pubmed	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	HNRNPDL EXOSC10 HMCN2 OSBPL3 MICAL3 SPEN MYRF	1.41e-05	283	96	7	18854154
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	HNRNPDL PALS1 EXOSC10 HMCN2 TXNDC5 IPO7 DHX40 FLAD1 RPS19BP1 PNO1 PC HNRNPH3 PPP1CA PPP1CC	1.78e-05	1335	96	14	29229926
Pubmed	Ephrin-B-dependent thymic epithelial cell-thymocyte interactions are necessary for correct T cell differentiation and thymus histology organization: relevance for thymic cortex development.	EPHB2 EFNB1	2.26e-05	3	96	2	23408838
Pubmed	Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia.	SLC28A2 SLC28A1	2.26e-05	3	96	2	12411296
Pubmed	Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine.	SLC28A2 SLC28A1	2.26e-05	3	96	2	10087507
Pubmed	Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network.	PPP1CA PPP1CC	2.26e-05	3	96	2	19074462
Pubmed	Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3.	SLC28A2 SLC28A1	2.26e-05	3	96	2	17453413
Pubmed	Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipids.	MARK1 MARK3	2.26e-05	3	96	2	21145462
Pubmed	1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription.	PPP1CA PPP1CC	2.26e-05	3	96	2	25073485
Pubmed	Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock.	PPP1CA PPP1CC	2.26e-05	3	96	2	21712997
Pubmed	NOM1 targets protein phosphatase I to the nucleolus.	PPP1CA PPP1CC	2.26e-05	3	96	2	17965019
Pubmed	Nuk controls pathfinding of commissural axons in the mammalian central nervous system.	EPHB2 EFNB1	2.26e-05	3	96	2	8689685
Pubmed	EPH receptor B2 stimulates human monocyte adhesion and migration independently of its EphrinB ligands.	EPHB2 EFNB1	2.26e-05	3	96	2	32337793
Pubmed	The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation.	PPP1CA PPP1CC	2.26e-05	3	96	2	12138106
Pubmed	Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization.	PPP1CA PPP1CC	2.26e-05	3	96	2	7857673
Pubmed	Unidirectional Eph/ephrin signaling creates a cortical actomyosin differential to drive cell segregation.	EPHB2 EFNB1	2.26e-05	3	96	2	27810913
Pubmed	Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells.	PPP1CA PPP1CC	2.26e-05	3	96	2	11739654
Pubmed	Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importance.	SLC28A2 SLC28A1	2.26e-05	3	96	2	28385889
Pubmed	Expression and localisation of ephrin-B1, EphB2, and EphB4 in the mouse testis during postnatal development.	EPHB2 EFNB1	2.26e-05	3	96	2	32620380
Pubmed	Myr 8, a novel unconventional myosin expressed during brain development associates with the protein phosphatase catalytic subunits 1alpha and 1gamma1.	PPP1CA PPP1CC	2.26e-05	3	96	2	11588169
Pubmed	Epigenetic clustering of gastric carcinomas based on DNA methylation profiles at the precancerous stage: its correlation with tumor aggressiveness and patient outcome.	ADAM23 GPSM1	2.26e-05	3	96	2	25740824
Pubmed	EphrinB1-EphB signaling regulates thymocyte-epithelium interactions involved in functional T cell development.	EPHB2 EFNB1	2.26e-05	3	96	2	17668899
Pubmed	Characterization of deoxyribonucleoside transport mediated by concentrative nucleoside transporters.	SLC28A2 SLC28A1	2.26e-05	3	96	2	33910126
Pubmed	Characterization of protein phosphatases in mouse oocytes.	PPP1CA PPP1CC	2.26e-05	3	96	2	9882488
Pubmed	EphB and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells.	EPHB2 EFNB1	2.26e-05	3	96	2	23711177
Pubmed	Expression profile of EFNB1, EFNB2, two ligands of EPHB2 in human gastric cancer.	EPHB2 EFNB1	2.26e-05	3	96	2	12136247
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ARHGAP5 PALS1 MARK1 MARK3 MICAL3 ECH1 C2CD5 NOMO1	2.26e-05	421	96	8	36976175
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	HNRNPDL EXOSC10 EFNB1 TXNDC5 IPO7 LMO7 SLC20A1 SYNE2 SPEN RBM39 HNRNPH3 PPP1CA	2.56e-05	1024	96	12	24711643
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	VPS13D EDC3 AKAP9 LMO7 MARK3 OSBPL3 SYNE2 FRYL PC DENND1A PPP1CA	2.61e-05	861	96	11	36931259
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	PALS1 SPATS2L TXNDC5 NOMO2 OSBPL3 FLAD1 PNO1 SH3GLB2 MYRF C2CD5	3.06e-05	719	96	10	35337019
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	HNRNPDL EDC3 SPATS2L LMO7 DDX60 DYSF SPEN RAB3B PPP1CA PPP1CC	3.24e-05	724	96	10	36232890
Pubmed	Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.	PC PPP1CA PPP1CC	3.95e-05	24	96	3	27754788
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	EPHB2 AKAP9 NOMO2 MARK1 MARK3 NOMO3 NCS1 C2CD5 PPP1CA NOMO1 PPP1CC	4.32e-05	910	96	11	36736316
Pubmed	Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.	PPP1CA PPP1CC	4.51e-05	4	96	2	23499489
Pubmed	Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein.	PPP1CA PPP1CC	4.51e-05	4	96	2	16131488
Pubmed	Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1.	PPP1CA PPP1CC	4.51e-05	4	96	2	10194355
Pubmed	Eph receptor interclass cooperation is required for the regulation of cell proliferation.	EPHB2 EFNB1	4.51e-05	4	96	2	27565439
Pubmed	ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites.	EPHB2 EFNB1	4.51e-05	4	96	2	7651410
Pubmed	NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1.	PPP1CA PPP1CC	4.51e-05	4	96	2	10880350
Pubmed	GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies.	RAB3D RAB3B	4.51e-05	4	96	2	34551092
Pubmed	Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis.	PPP1CA PPP1CC	4.51e-05	4	96	2	15226296
Pubmed	Role of the transporter regulator protein (RS1) in the modulation of concentrative nucleoside transporters (CNTs) in epithelia.	SLC28A2 SLC28A1	4.51e-05	4	96	2	22492015
Pubmed	EphB receptors and ephrin-B3 regulate axon guidance at the ventral midline of the embryonic mouse spinal cord.	EPHB2 EFNB1	4.51e-05	4	96	2	16943546
Pubmed	Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1.	PPP1CA PPP1CC	4.51e-05	4	96	2	22768081
Pubmed	Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif.	PPP1CA PPP1CC	4.51e-05	4	96	2	10807923
Pubmed	Nuclear protein phosphatase-1 regulates HIV-1 transcription.	PPP1CA PPP1CC	4.51e-05	4	96	2	12788939
Pubmed	Rim1 and rabphilin-3 bind Rab3-GTP by composite determinants partially related through N-terminal alpha -helix motifs.	RAB3D RAB3C	4.51e-05	4	96	2	11431472
Pubmed	Redox modification of nuclear actin by MICAL-2 regulates SRF signaling.	MICAL2 MICAL3	4.51e-05	4	96	2	24440334
Pubmed	Mechanisms Regulating the Association of Protein Phosphatase 1 with Spinophilin and Neurabin.	PPP1R3A PPP1CA	4.51e-05	4	96	2	29786422
Pubmed	Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.	SLC28A2 SLC28A1	4.51e-05	4	96	2	18635603
Pubmed	The MICAL proteins and rab1: a possible link to the cytoskeleton?	MICAL2 MICAL3	4.51e-05	4	96	2	15694364
Pubmed	Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx.	PPP1CA PPP1CC	4.51e-05	4	96	2	23277204
Pubmed	The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits.	PPP1CA PPP1CC	4.51e-05	4	96	2	12016225
Interaction	RPH3A interactions	PALS1 RAB3D RAB3B RAB3C HTT	1.12e-06	39	96	5	int:RPH3A
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPP1CA PPP1CC	1.15e-03	13	71	2	693
GeneFamily	RNA binding motif containing	HNRNPDL SPEN RBM39 HNRNPH3 LARP7	1.50e-03	213	71	5	725
GeneFamily	LIM domain containing	LMO7 MICAL2 MICAL3	1.61e-03	59	71	3	1218
GeneFamily	RAB, member RAS oncogene GTPases	RAB3D RAB3B RAB3C	2.13e-03	65	71	3	388
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP25 MMP17	3.97e-03	24	71	2	891
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	EPHB2 HNRNPDL FAT1 SLC11A2 AKAP9 IPO7 MARK3 MICAL2 SYNE2 MICAL3 FRYL SPEN RBM39 HNRNPH3 C2CD5	5.06e-07	856	96	15	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	HNRNPDL FAT1 AKAP9 IPO7 MARK3 MICAL3 FRYL SPEN RBM39 C2CD5	8.26e-06	466	96	10	M13522
Coexpression	GSE26559_TCF1_KO_VS_WT_LIN_NEG_CELL_UP	AKAP9 RRAGD MARK3 MICAL2 NINL MYRF MICU1	8.53e-06	198	96	7	M8423
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLXNA3 ZNF677 LAMA4 PNO1 TTC27 GPSM1	3.04e-06	185	96	6	9878392d79734ab5bb977d7f4f5e2e079b9a5353
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP9 KIF27 OSBPL3 SYNE2 CFAP44 HYDIN	4.36e-06	197	96	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MMP25 CADPS DNAJB7 RAB3B VWDE	3.09e-05	167	96	5	c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FAT1 SYNE2 MICAL3 MYRF HYDIN	3.18e-05	168	96	5	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	SEMA3D ADAM23 LAMA4 DYSF MMP17	3.55e-05	172	96	5	c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADPS GLRA3 ASIC5 RAB3B ITIH1	3.55e-05	172	96	5	2651dece87c3e3d2d6370f5274ebae357474b825
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(INS+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RRAGD CADPS GLRA3 ASIC5 RAB3B	3.97e-05	176	96	5	6b04672f295d7680ba00714a72785314a619c893
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3D MICAL2 LAMA4 MMP17 GPSM1	4.07e-05	177	96	5	c274fbdc141855ff4581d437d4997c64cc193278
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3D MICAL2 LAMA4 MMP17 GPSM1	4.07e-05	177	96	5	f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3D MICAL2 LAMA4 MMP17 GPSM1	4.07e-05	177	96	5	c8a51e480b978dc0ded85583261f2c892e085be8
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 EFNB1 CADPS MARK1 RAB3B	4.41e-05	180	96	5	6327c938a4f99df9fee714e44f15ea4a4a63ae15
ToppCell	RV\|World / Chamber and Cluster_Paper	AKAP9 ADAM23 MARK3 LAMA4 MICAL3	4.53e-05	181	96	5	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB2 B3GNT9 RRAGD MARK1 LAMA4	5.03e-05	185	96	5	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 SPATS2L SLC28A1 MICAL3 HYDIN	5.16e-05	186	96	5	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPATS2L SYNE2 NINL MICAL3 HYDIN	5.16e-05	186	96	5	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 SPATS2L SLC28A1 MICAL3 DENND1A	5.29e-05	187	96	5	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 SYNE2 NINL LAMA4 MICAL3	5.56e-05	189	96	5	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 SYNE2 NINL LAMA4 MICAL3	5.56e-05	189	96	5	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GARNL3 HMCN2 CADPS MICAL2 LAMA4	5.70e-05	190	96	5	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GARNL3 HMCN2 CADPS MICAL2 LAMA4	5.70e-05	190	96	5	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADPS GLRA3 ASIC5 RAB3B RAB3C	5.99e-05	192	96	5	5692bd57093852d442400383850f416c497dcc7d
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADPS GLRA3 ASIC5 RAB3B RAB3C	5.99e-05	192	96	5	0b506fb5bca54a50949932293c6f86d974a3acdd
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP1R3A SEMA3D B3GNT9 ADAM23 LAMA4	5.99e-05	192	96	5	1b228f0929b505de82a39bf64c837887b0e56701
ToppCell	mild-Myeloid-Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MMP25 TRANK1 SPATS2L DDX60 DYSF	6.61e-05	196	96	5	ded44b38ea489946e9eedfe752b5a9fde9149c16
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GARNL3 HMCN2 MARK1 LAMA4 MICAL3	6.77e-05	197	96	5	bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 FAT1 LMO7 SYNE2 HYDIN	6.77e-05	197	96	5	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GARNL3 MARK1 LAMA4 MICAL3 NCS1	6.93e-05	198	96	5	bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EXOSC10 FAT1 VPS13D AKAP9 RBM39	7.10e-05	199	96	5	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	SLC11A2 AKAP9 LMO7 SYNE2 LARP7	7.10e-05	199	96	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GARNL3 MARK1 LAMA4 MICAL3 NCS1	7.10e-05	199	96	5	b1753474152b82a0b811b9878c890a359e14919a
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	SPATS2L AKAP9 LMO7 SYNE2 LARP7	7.10e-05	199	96	5	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	AKAP9 DDX60 SYNE2 FRYL RBM39	7.27e-05	200	96	5	12f1685ce8f218433068e090c9d839cd5a1910bf
Disease	visual impairment and progressive phthisis bulbi (implicated_via_orthology)	MARK1 MARK3	6.00e-05	4	94	2	DOID:0070356 (implicated_via_orthology)
Disease	cancer (implicated_via_orthology)	ERCC4 PIK3CD FLAD1 GPSM1 PPP1CA PPP1CC	2.22e-04	268	94	6	DOID:162 (implicated_via_orthology)
Disease	PITUITARY DWARFISM I	ERCC4 LARP7	3.56e-04	9	94	2	C0342573
Disease	type 2 diabetes mellitus (implicated_via_orthology)	PPP1R3A PIK3CD PPP1CA PPP1CC	3.61e-04	105	94	4	DOID:9352 (implicated_via_orthology)
Disease	bipolar disorder	ERCC4 TRANK1 SPATS2L GARNL3 DNAJB7 PC ITIH1 PPP1CC	5.20e-04	577	94	8	MONDO_0004985
Disease	phosphatidylcholine 40:7 measurement	ADAM23 NOMO1	7.65e-04	13	94	2	EFO_0021477
Disease	cutaneous melanoma, hair color	LMO7 MARK3 SYNE2	1.03e-03	62	94	3	EFO_0000389, EFO_0003924
Disease	level of Phosphatidylcholine (18:0_20:3) in blood serum	MYRF NOMO1	1.17e-03	16	94	2	OBA_2045093
Disease	neurodegenerative disease (implicated_via_orthology)	MARK1 MARK3 HTT MICU1	1.21e-03	145	94	4	DOID:1289 (implicated_via_orthology)
Disease	Manic Disorder	TRANK1 PC ITIH1	1.53e-03	71	94	3	C0024713
Disease	unipolar depression, bipolar disorder	ERCC4 OSBPL3 SYNE2 DENND1A	1.58e-03	156	94	4	EFO_0003761, MONDO_0004985
Disease	hydrocephalus (implicated_via_orthology)	KIF27 HYDIN	1.66e-03	19	94	2	DOID:10908 (implicated_via_orthology)
Disease	citrulline measurement	HMCN2 GLP2R	1.84e-03	20	94	2	EFO_0009777
Disease	bipolar disorder, schizophrenia, response to lithium ion	ERCC4 SPATS2L	1.84e-03	20	94	2	GO_0010226, MONDO_0004985, MONDO_0005090
Disease	alcohol consumption measurement	ERCC4 AKAP9 CADPS MARK3 RPS19BP1 GLRA3 MICAL3 DENND1A LARP7 HTT PPP1CC	1.99e-03	1242	94	11	EFO_0007878
Disease	Manic	TRANK1 PC ITIH1	2.00e-03	78	94	3	C0338831
Disease	Depression, Bipolar	TRANK1 PC ITIH1	2.08e-03	79	94	3	C0005587
Disease	neuroimaging measurement	SEMA3D CADPS MARK3 NINL FRYL ARMC9 DYSF PC DENND1A HTT	2.16e-03	1069	94	10	EFO_0004346
Disease	urate measurement	NAALADL1 SPATS2L RRAGD MARK3 SLC28A1 NINL DYSF PC CDCA7L	2.23e-03	895	94	9	EFO_0004531
Disease	Etat Marbre	HTT MICU1	2.43e-03	23	94	2	C0266487
Disease	Dwarfism	ERCC4 LARP7	2.87e-03	25	94	2	C0013336
Disease	risk-taking behaviour	ERCC4 SPATS2L CADPS MARK3 TTC27 PC DENND1A HTT	3.07e-03	764	94	8	EFO_0008579
Disease	Limb-girdle muscular dystrophy	HNRNPDL DYSF	3.10e-03	26	94	2	cv:C0686353

Protein segments in the cluster

Peptide	Gene	Start	Entry
DQIGFQTFETVDVKF	AKAP9	1496	Q99996
ASFQIEAFGSKFILD	ADAM23	151	O75077
ATGSKDQTVFFFEVE	CFAP44	591	Q96MT7
AEGTVFTEEDFQKFQ	RPS19BP1	116	Q86WX3
AFGAVAEFSFVIDLQ	RBM39	386	Q14498
DINFVFTGFSVNGKV	NOMO3	121	P69849
QLGFDFFEASAKENI	RAB3B	156	P20337
GFEFFETSAKDNINV	RAB3C	166	Q96E17
DLGFEFFEASAKENI	RAB3D	156	O95716
LFFANEKGANFHEVT	GLRA3	131	O75311
FGFVLFKDAASVDKV	HNRNPDL	191	O14979
FFGVADKAQHVFSLD	PCDHGB7	281	Q9Y5F8
QDFQFVVKATDGGFL	PCDHB1	526	Q9Y5F3
AEFGQFFHATLIKAV	KBTBD3	491	Q8NAB2
AFFNAVKEGDTVIFA	CADPS	591	Q9ULU8
FFFTIVTGNDEKAFE	FAT1	3476	Q14517
FDAIANIRGETFFFK	MMP25	321	Q9NPA2
DINFVFTGFSVNGKV	NOMO2	121	Q5JPE7
GFDGNSIFNFKEVEV	KIAA0100	776	Q14667
EEISGVAFIFNQKFF	MICAL3	261	Q7RTP6
TFVFNVFDENKDGRI	NCS1	66	P62166
FISDFAVTADGNAFI	ITIH1	96	P19827
AGDFKTGVAFFEAAV	GPSM1	41	Q86YR5
FQKVGDFSAAFEILS	HMCN2	2741	Q8NDA2
DLVAAFDNGDQKVFF	ARMC9	61	Q7Z3E5
FFLFKLGAVENAAES	DDX60	1131	Q8IY21
GKGLTFQEVENFFTF	MICU1	356	Q9BPX6
KESFANAGFTSFDVV	EPHB2	931	P29323
TFDFVFGKNSTQDEV	KIF27	46	Q86VH2
SKETGVRFAGADFVF	PLXNA3	621	P51805
ADALAKAVAENFFVE	FHIP2B	361	Q86V87
NEFAEVFLKAFAVGV	IPO7	286	O95373
AFFQVKEVDVGLAAD	ECH1	191	Q13011
QFGVFKDFDFLDVEL	FRYL	2421	O94915
TNKDGFVDFLEFIAA	GUCA1C	66	O95843
DINFVFTGFSVNGKV	NOMO1	121	Q15155
ENDDFFVRKTGVFHA	LMO7	511	Q8WWI1
STGEAFVQFASKEIA	HNRNPH3	56	P31942
KGFAFVEFETKEQAA	LARP7	166	Q4G0J3
NVFVVSVFAEAFFGK	SLC11A2	311	P49281
SVFAEAFFGKTNEQV	SLC11A2	316	P49281
FALENFTVSAAKFAE	CDCA7L	281	Q96GN5
FEGNLALFDKAAVFE	EDC3	206	Q96F86
TKAADFVKAFILGFQ	PNO1	131	Q9NRX1
FDTNFFGAVRLVKAV	RDH8	111	Q9NYR8
AFNKVAVYDTDVFAL	OTOP2	51	Q7RTS6
FADSFGFNLVSVKEF	PPP1R3A	66	Q16821
VSRQAFEADIAAGKF	PALS1	531	Q8N3R9
RGVSFTFGAEVVAKF	PPP1CA	221	P62136
FFLVNSVANEEGFAK	DNAJB7	221	Q7Z6W7
DADSFVKFALGSVVA	EXOSC10	31	Q01780
DSDQVFIGFVLKQFE	HTT	1466	P42858
ERETFQKFSVNGDFI	IGSF1	456	Q8N6C5
FTIENQGVTDFKFAL	HYDIN	3191	Q4G0P3
FSFITDDQVEGFAKL	GLP2R	401	O95838
FDLVKNGESIASFFQ	C1QTNF5	166	Q9BXJ0
DGFFNSKVALFAAVG	EFNB1	231	P98172
RFQTDAVAKFGVIFF	ASIC5	116	Q9NY37
IKIADFGFSNEFTVG	MARK1	196	Q9P0L2
NIKIADFGFSNEFTV	MARK3	191	P27448
DGVARAFLKAQAAFF	DENND1A	306	Q8TEH3
VTFEAVAQAFGDELK	FLAD1	186	Q8NFF5
KAGGFNDFATLAVIF	DHX40	546	Q8IX18
FISNSGIEKAFLFDV	RRAGD	251	Q9NQL2
IAFVLAFSVGANDVA	SLC20A1	31	Q8WUM9
EFNQFAEGKLSVFAE	DYSF	866	O75923
DAFVEVKFGNTTFKT	C2CD5	26	Q86YS7
EQEGSVNFKFGVLFA	GARNL3	196	Q5VVW2
EEISGVAFIFNQKFF	MICAL2	261	O94851
IREDKGFQFFSEQVS	OSBPL3	616	Q9H4L5
DESFNIGLKFEIAFE	LAMA4	1661	Q16363
FDFNVDKAVQAFVDG	SPATS2L	36	Q9NUQ6
EFEFVLSQFKDFGVR	SYNE2	5491	Q8WXH0
FDAVAQIRGEAFFFK	MMP17	336	Q9ULZ9
FTRAVQFTEEKFGQA	SH3GLB2	16	Q9NR46
TVNAVAGALKAFFAD	ARHGAP5	1326	Q13017
VNFEEFKEGFVAVLS	NINL	61	Q9Y2I6
GFDFFNKITNVSAVI	PI4KAP2	201	A4QPH2
ADVFIVFTDNETFAG	RO60	461	P10155
FVFGDTLVKDVFAFQ	SLC28A2	246	O43868
ADEKVIFGIEFNSTF	SEMA3D	596	O95025
DVRFVFKGDADVFVN	B3GNT9	221	Q6UX72
VAIESQEFFAGFKLQ	VWDE	281	Q8N2E2
GVAAFVDFVDIKSAQ	SPEN	46	Q96T58
LVNVKFEGSEESFTF	PIK3CD	191	O00329
FGKRDFENNSVFIVD	UNQ9370/PRO34162	151	Q6UXP9
RGVSFTFGAEVVAKF	PPP1CC	221	P36873
FVFGEALVKDVFAFQ	SLC28A1	251	O00337
GLFTFKDVAIEFSQE	ZNF677	6	Q86XU0
NFDDTIAEGITFIKF	TXNDC5	331	Q8NBS9
IKAFTDNAVAFDTGF	ERCC4	161	Q92889
VKSCFEFFGISQVDA	TRANK1	2066	O15050
LFQQFSEVKGLDAFV	TTC27	126	Q6P3X3
AAFGNGALFVEKFIE	PC	226	P11498
FLAFGDVTVDFTQKE	ZNF337	11	Q9Y3M9
FVNRFTVNSDDFGIK	WDR64	236	B1ANS9
GLVSLKFQDFEVEFS	VPS13D	1641	Q5THJ4
IGSTEFTEEFFNKLQ	NAALADL1	421	Q9UQQ1
ADKGFNFSVGDDAFV	MYRF	381	Q9Y2G1