Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Ephrin_rec_like	EPHB6 EPHA7	2.31e-04	11	39	2	PF07699
Domain	RECEPTOR_TYR_KIN_V_2	EPHB6 EPHA7	3.81e-04	14	39	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB6 EPHA7	3.81e-04	14	39	2	PS00790
Domain	EphA2_TM	EPHB6 EPHA7	3.81e-04	14	39	2	PF14575
Domain	Tyr_kinase_ephrin_rcpt	EPHB6 EPHA7	3.81e-04	14	39	2	IPR016257
Domain	Eph_TM	EPHB6 EPHA7	3.81e-04	14	39	2	IPR027936
Domain	Ephrin_rcpt_lig-bd_dom	EPHB6 EPHA7	3.81e-04	14	39	2	IPR001090
Domain	Tyr_kinase_rcpt_V_CS	EPHB6 EPHA7	3.81e-04	14	39	2	IPR001426
Domain	EPH_LBD	EPHB6 EPHA7	3.81e-04	14	39	2	PS51550
Domain	EPH_lbd	EPHB6 EPHA7	3.81e-04	14	39	2	SM00615
Domain	Ephrin_lbd	EPHB6 EPHA7	3.81e-04	14	39	2	PF01404
Domain	Ephrin_rec_like	EPHB6 EPHA7	1.24e-03	25	39	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHB6 EPHA7	1.24e-03	25	39	2	IPR011641
Domain	SAM_2	EPHB6 EPHA7	3.63e-03	43	39	2	PF07647
Domain	-	EPHB6 EPHA7	1.02e-02	73	39	2	2.60.120.260
Pubmed	Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome.	EPHB6 EPHA7	1.22e-05	5	39	2	21935409
Pubmed	PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.	EPHB6 EPHA7	4.39e-05	9	39	2	9707552
Pubmed	Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.	OLFM1 EPHA7	5.48e-05	10	39	2	22095909
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	GRAMD1B AKAP11 SH2D1A CLK2 CTR9 EPM2AIP1 EPHA7	6.08e-05	910	39	7	36736316
Pubmed	Cloning, central nervous system expression and chromosomal mapping of the mouse PAK-1 and PAK-3 genes.	GRPR CTR9	6.70e-05	11	39	2	10352232
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	EPHB6 SPEN MYO9A GPR149 EPHA7	1.03e-04	420	39	5	28065597
Pubmed	Genetic loci that control the angiogenic response to basic fibroblast growth factor.	ENPP2 EPHA7	1.46e-04	16	39	2	15226265
Pubmed	Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.	EPHB6 EPHA7	1.65e-04	17	39	2	12217323
Pubmed	Expression of Ephs and ephrins in developing mouse inner ear.	EPHB6 EPHA7	2.07e-04	19	39	2	12684176
Pubmed	Eph receptors and ephrins: effectors of morphogenesis.	EPHB6 EPHA7	2.30e-04	20	39	2	10207129
Pubmed	Multiple roles of EPH receptors and ephrins in neural development.	EPHB6 EPHA7	2.30e-04	20	39	2	11256076
Pubmed	The Eph family receptors and ligands.	EPHB6 EPHA7	2.30e-04	20	39	2	9576626
Pubmed	The ephrins and Eph receptors in neural development.	EPHB6 EPHA7	2.30e-04	20	39	2	9530499
Pubmed	Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.	EPHB6 EPHA7	2.54e-04	21	39	2	9267020
Pubmed	Developmental expression of Eph and ephrin family genes in mammalian small intestine.	EPHB6 EPHA7	2.54e-04	21	39	2	20112066
Pubmed	Eph receptors and ephrins demarcate cerebellar lobules before and during their formation.	EPHB6 EPHA7	2.54e-04	21	39	2	10495276
Pubmed	Roles of Eph receptors and ephrins in segmental patterning.	EPHB6 EPHA7	2.54e-04	21	39	2	11128993
Pubmed	Eph receptors and ephrins: regulators of guidance and assembly.	EPHB6 EPHA7	2.54e-04	21	39	2	10730216
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	AKAP11 SPEN CTR9 VPS33A	2.78e-04	282	39	4	23667531
Pubmed	Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.	EPHB6 EPHA7	3.05e-04	23	39	2	19542359
Pubmed	Eph receptors and their ephrin ligands are expressed in developing mouse pancreas.	EPHB6 EPHA7	3.33e-04	24	39	2	16446123
Pubmed	Intrinsically Disordered Protein TEX264 Mediates ER-phagy.	RBM14 AKAP11 CTR9	4.32e-04	131	39	3	31006538
Pubmed	Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development.	GPR149 EPHA7	8.40e-04	38	39	2	31597102
Pubmed	Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.	EPHB6 EPHA7	1.03e-03	42	39	2	11439183
Cytoband	13q14.11	AKAP11 CPB2	5.11e-04	39	39	2	13q14.11
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB6 EPHA7	1.52e-04	14	24	2	1095
GeneFamily	Sterile alpha motif domain containing	EPHB6 EPHA7	6.03e-03	88	24	2	760
GeneFamily	Fibronectin type III domain containing	EPHB6 EPHA7	1.89e-02	160	24	2	555
Coexpression	GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDC_UP	RBM14 ZNF598 CTSA PTGER4 GRPR	1.15e-05	200	39	5	M3970
Disease	p-tau:beta-amyloid 1-42 ratio measurement	TBC1D22A EPHA7	2.58e-04	19	37	2	EFO_0007709
Disease	chronic hepatitis C virus infection	OLFM1 EPHA7	7.88e-04	33	37	2	EFO_0004220
Disease	Ovarian Cysts	MFAP2 PTGER4	8.87e-04	35	37	2	C0029927
Disease	Corpus Luteum Cyst	MFAP2 PTGER4	8.87e-04	35	37	2	C0010093
Disease	Lymphoma	SH2D1A PTGER4	1.16e-03	40	37	2	C0024299
Disease	t-tau:beta-amyloid 1-42 ratio measurement	TBC1D22A EPHA7	3.12e-03	66	37	2	EFO_0007708
Disease	eotaxin measurement	TBC1D22A CLK2	4.55e-03	80	37	2	EFO_0008122
Disease	response to selective serotonin reuptake inhibitor	OLFM1 TEAD4	4.77e-03	82	37	2	EFO_0005658
Disease	cortical surface area measurement	MFAP2 TMEM8B TBC1D22A ENPP2 RHOT1 EPHA7	6.13e-03	1345	37	6	EFO_0010736
Disease	urate measurement, bone density	GRAMD1B OLFM1 GPR149 PARG	7.32e-03	619	37	4	EFO_0003923, EFO_0004531

Protein segments in the cluster

Peptide	Gene	Start	Entry
DEHYRTYDAYSTFYL	C6orf136	251	Q5SQH8
RGDAYYDTDYRHSYE	CLK2	86	P49760
YDTDYRHSYEYQREN	CLK2	91	P49760
HDSVYYTYEDYAKSI	AKAP11	481	Q9UKA4
DVPYHDYFYTINRYT	GRAMD1B	471	Q3KR37
AHSDYARYSGSYNDY	RBM14	641	Q96PK6
DTSYYIRYRGAVYAD	FEM1C	336	Q96JP0
FYEVDYNSFHETYET	KCNJ6	346	P48051
YTHYITTYEEYQAQR	ASAH2	576	Q9NR71
IYRYQSHDYAFSSVE	PCYOX1	166	Q9UHG3
EDHKSYYAINTVYVY	RHOT1	451	Q8IXI2
TEQYSEYTGYAETYR	PARG	786	Q86W56
ERYLAINHAYFYSHY	PTGER4	116	P35408
YAYQTNASTYEYIDI	OLFM1	426	Q99784
YYYETDYDTGRNIRE	EPHA7	126	Q15375
SYGIYKIAHEDYYDD	GPR149	406	Q86SP6
YYDYVLASDVVYHHY	METTL21C	186	Q5VZV1
YEQNDNSLVYFAYYH	CTSA	211	P10619
SASYYEQYHSLNEIY	CPB2	116	Q96IY4
RHYEAEHEYYERYVA	EPM2AIP1	56	Q7L775
HVIYLYRSYHYSEVD	GRPR	281	P30550
FHVQEDYDQAFQYYY	CTR9	316	Q6PD62
HESTRDYIYYNDVYA	KLHDC4	196	Q8TBB5
EGSYNRYYSHVDYRD	PPHLN1	46	Q8NEY8
YRTRYDILYHTDFES	ENPP2	606	Q13822
THYSDQIDNPDYYDY	MFAP2	36	P55001
YYSSIAIAYVAYRAD	OR2AT4	256	A6NND4
AHTYLYIEFVDIYYS	SLC9C1	316	Q4G0N8
LYHGYIYTYRVSQTE	SH2D1A	46	O60880
YQLRYYDQAEDESHS	EPHB6	521	O15197
QKHDDYVYDIYYLET	SLC7A6OS	191	Q96CW6
AFYEHAQTYYYTEIR	TRAPPC11	191	Q7Z392
RASYDYNQDRTYYES	SPEN	621	Q96T58
YHVYGTDVYASYSSV	VIT	71	Q6UXI7
LYAFVETRDNYFYIH	TMEM8B	396	A6NDV4
ETEYARYENGHYSYR	TEAD4	346	Q15561
EYFAFIEHYYDSRND	TBC1D22A	256	Q8WUA7
AQDYYSDYAYLREHF	ZNF598	221	Q86UK7
DYYKREILQTYGYEH	VPS33A	426	Q96AX1
VYQEHNERNYHVFYY	MYO9A	326	B2RTY4