Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondelta(3)-delta(2)-enoyl-CoA isomerase activity

EHHADH ECHS1

7.24e-054702GO:0004165
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN2C GRIN2D

3.35e-048702GO:0022849
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN2C GRIN2D

3.35e-048702GO:0004972
GeneOntologyMolecularFunctionthyroid hormone transmembrane transporter activity

SLCO1C1 SLCO4A1

4.29e-049702GO:0015349
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A2 COL17A1 COL27A1

5.62e-0446703GO:0030020
GeneOntologyMolecularFunctionenoyl-CoA hydratase activity

EHHADH ECHS1

7.82e-0412702GO:0004300
GeneOntologyMolecularFunctionATP hydrolysis activity

MMAA ABCC4 MDN1 DDX51 CHD4 CHD7 DNAH9

8.84e-04441707GO:0016887
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

ABCC4 SLCO4A1

1.07e-0314702GO:0015132
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

ABCC4 SLCO4A1

1.24e-0315702GO:0071714
GeneOntologyMolecularFunctionATP-dependent activity

MMAA DNHD1 ABCC4 MDN1 DDX51 CHD4 CHD7 DNAH9

1.35e-03614708GO:0140657
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIN2C GRIN2D

1.59e-0317702GO:0004970
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH9

1.79e-0318702GO:0008569
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO1C1 SLCO4A1

1.79e-0318702GO:0015347
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

ABCC4 SLCO1C1 AQP9

1.91e-0370703GO:1901618
GeneOntologyMolecularFunctionintramolecular oxidoreductase activity, transposing C=C bonds

EHHADH ECHS1

1.99e-0319702GO:0016863
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCC4 SLCO1C1 SLCO4A1

2.15e-0373703GO:0170055
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

GRID2IP TRPM1 GRIN2C GRIN2D

4.54e-0559694GO:0007215
GeneOntologyBiologicalProcessregulation of humoral immune response mediated by circulating immunoglobulin

CD55 LTA SVEP1

5.27e-0522693GO:0002923
GeneOntologyCellularComponentcerebellar granule cell to Purkinje cell synapse

GRID2IP CHD4

2.17e-047682GO:0150048
GeneOntologyCellularComponentpostsynaptic membrane

MAGI2 GRID2IP CELSR3 GRIN2C GRIN2D CNTN2 GPR179

3.41e-04405687GO:0045211
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN2C GRIN2D

3.70e-049682GO:0017146
DomainEnoyl-CoA_hyd/isom_CS

EHHADH ECHS1

3.61e-048682IPR018376
DomainENOYL_COA_HYDRATASE

EHHADH ECHS1

5.77e-0410682PS00166
DomainOA_transporter

SLCO1C1 SLCO4A1

8.42e-0412682IPR004156
DomainOATP

SLCO1C1 SLCO4A1

8.42e-0412682PF03137
DomainP-loop_NTPase

MMAA DNHD1 MAGI1 MAGI2 ABCC4 MDN1 DDX51 CHD4 CHD7 DNAH9

9.41e-048486810IPR027417
DomainDynein_HC_stalk

DNHD1 DNAH9

1.16e-0314682IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH9

1.16e-0314682IPR013602
DomainDHC_N2

DNHD1 DNAH9

1.16e-0314682PF08393
DomainMT

DNHD1 DNAH9

1.16e-0314682PF12777
DomainATPase_dyneun-rel_AAA

MDN1 DNAH9

1.16e-0314682IPR011704
DomainAAA_5

MDN1 DNAH9

1.16e-0314682PF07728
DomainDHC_fam

DNHD1 DNAH9

1.33e-0315682IPR026983
DomainDynein_heavy_dom

DNHD1 DNAH9

1.33e-0315682IPR004273
DomainDynein_heavy

DNHD1 DNAH9

1.33e-0315682PF03028
DomainGuanylate_kinase_CS

MAGI1 MAGI2

1.52e-0316682IPR020590
DomainCrotonase_core_superfam

EHHADH ECHS1

1.71e-0317682IPR001753
DomainECH_1

EHHADH ECHS1

1.71e-0317682PF00378
DomainAAA+_ATPase

MMAA ABCC4 MDN1 DNAH9

1.88e-03144684IPR003593
DomainAAA

MMAA ABCC4 MDN1 DNAH9

1.88e-03144684SM00382
DomainIontro_rcpt

GRIN2C GRIN2D

1.92e-0318682IPR001320
DomainLig_chan-Glu_bd

GRIN2C GRIN2D

1.92e-0318682PF10613
DomainIono_rcpt_met

GRIN2C GRIN2D

1.92e-0318682IPR001508
DomainGlu/Gly-bd

GRIN2C GRIN2D

1.92e-0318682IPR019594
DomainLig_chan-Glu_bd

GRIN2C GRIN2D

1.92e-0318682SM00918
DomainLig_chan

GRIN2C GRIN2D

1.92e-0318682PF00060
DomainPBPe

GRIN2C GRIN2D

1.92e-0318682SM00079
Domain-

EHHADH ECHS1

2.62e-03216823.90.226.10
DomainClpP/crotonase-like_dom

EHHADH ECHS1

2.62e-0321682IPR029045
DomainGUANYLATE_KINASE_2

MAGI1 MAGI2

3.15e-0323682PS50052
DomainGUANYLATE_KINASE_1

MAGI1 MAGI2

3.15e-0323682PS00856
DomainChromo_domain

CHD4 CHD7

3.42e-0324682IPR023780
DomainCollagen

COL4A2 COL17A1 COL27A1

3.68e-0385683IPR008160
DomainCollagen

COL4A2 COL17A1 COL27A1

3.68e-0385683PF01391
DomainGuanylate_kin

MAGI1 MAGI2

4.01e-0326682PF00625
DomainGK/Ca_channel_bsu

MAGI1 MAGI2

4.01e-0326682IPR008145
DomainGuanylate_kin-like_dom

MAGI1 MAGI2

4.01e-0326682IPR008144
DomainChromo

CHD4 CHD7

4.01e-0326682PF00385
DomainGuKc

MAGI1 MAGI2

4.01e-0326682SM00072
DomainCHROMO_1

CHD4 CHD7

4.64e-0328682PS00598
DomainCHROMO_2

CHD4 CHD7

4.64e-0328682PS50013
DomainFYVE

PLEKHF2 PLEKHF1

4.98e-0329682PF01363
DomainFYVE

PLEKHF2 PLEKHF1

4.98e-0329682SM00064
Domain-

MMAA DNHD1 ABCC4 MDN1 DDX51 CHD4 CHD7 DNAH9

5.56e-037466883.40.50.300
DomainSNF2_N

CHD4 CHD7

6.04e-0332682IPR000330
DomainChromodomain-like

CHD4 CHD7

6.04e-0332682IPR016197
DomainSNF2_N

CHD4 CHD7

6.04e-0332682PF00176
DomainChromo/shadow_dom

CHD4 CHD7

6.41e-0333682IPR000953
DomainCHROMO

CHD4 CHD7

6.41e-0333682SM00298
DomainZnf_FYVE-rel

PLEKHF2 PLEKHF1

6.80e-0334682IPR017455
DomainHelicase_C

DDX51 CHD4 CHD7

6.99e-03107683PF00271
DomainHELICc

DDX51 CHD4 CHD7

6.99e-03107683SM00490
DomainHelicase_C

DDX51 CHD4 CHD7

7.18e-03108683IPR001650
DomainDNA/RNA_helicase_DEAH_CS

CHD4 CHD7

7.19e-0335682IPR002464
DomainHELICASE_CTER

DDX51 CHD4 CHD7

7.36e-03109683PS51194
DomainHELICASE_ATP_BIND_1

DDX51 CHD4 CHD7

7.36e-03109683PS51192
DomainDEXDc

DDX51 CHD4 CHD7

7.36e-03109683SM00487
DomainHelicase_ATP-bd

DDX51 CHD4 CHD7

7.55e-03110683IPR014001
DomainKazal_2

SLCO1C1 SLCO4A1

7.60e-0336682PF07648
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A2 COL17A1 COL27A1 LOXL3

5.35e-0561484M27103
PathwayREACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS

GRIN2C GRIN2D

1.13e-045482MM15655
PathwayKEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM

GRIN2C GRIN2D

1.13e-045482M47667
PathwayKEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY

MAGI1 MAGI2

1.69e-046482M47523
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM

GRIN2C GRIN2D

1.69e-046482M47668
PathwayREACTOME_COLLAGEN_FORMATION

COL4A2 COL17A1 COL27A1 LOXL3

2.44e-0490484M631
PathwayWP_MITOCHONDRIAL_BETAOXIDATION

EHHADH ECHS1

4.03e-049482M45530
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A2 COL17A1 COL27A1

4.45e-0444483M27812
PathwayKEGG_LIMONENE_AND_PINENE_DEGRADATION

EHHADH ECHS1

5.02e-0410482M17395
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1C1 SLCO4A1

6.12e-0411482M930
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_LIGAND_GATED_CA2_CHANNEL

GRIN2C GRIN2D

7.33e-0412482M47953
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1C1 SLCO4A1

7.33e-0412482MM15476
Pubmed

Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons.

TRPM1 GPR179

3.99e-06270224114537
Pubmed

In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons.

GRIN2C GRIN2D

3.99e-06270229651654
Pubmed

Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.

GRIN2C GRIN2D

3.99e-06270231110197
Pubmed

Integrated Analysis of ECT2 and COL17A1 as Potential Biomarkers for Pancreatic Cancer.

COL17A1 ECT2

3.99e-06270235722628
Pubmed

Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice.

GRIN2C GRIN2D

3.99e-06270235057644
Pubmed

Co-expression of activin receptor-interacting protein 1 and 2 in mouse nerve cells.

MAGI1 MAGI2

3.99e-06270223523645
Pubmed

NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback.

GRIN2C GRIN2D

3.99e-06270231786200
Pubmed

MAGI1 copy number variation in bipolar affective disorder and schizophrenia.

MAGI1 MAGI2

3.99e-06270222381734
Pubmed

Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility.

GRIN2C GRIN2D

3.99e-06270229317596
Pubmed

NMDA GluN2C/2D receptors contribute to synaptic regulation and plasticity in the anterior cingulate cortex of adult mice.

GRIN2C GRIN2D

3.99e-06270233766086
Pubmed

Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunits.

GRIN2C GRIN2D

1.20e-0537029718984
Pubmed

Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens.

GRIN2C GRIN2D

1.20e-05370235867797
Pubmed

Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model.

GRIN2C GRIN2D

1.20e-05370233421565
Pubmed

Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels.

GRIN2C GRIN2D

1.20e-0537029480759
Pubmed

Functional correlation of NMDA receptor epsilon subunits expression with the properties of single-channel and synaptic currents in the developing cerebellum.

GRIN2C GRIN2D

2.39e-0547028699248
Pubmed

Role of the carboxy-terminal region of the GluR epsilon2 subunit in synaptic localization of the NMDA receptor channel.

GRIN2C GRIN2D

2.39e-0547029768843
Pubmed

Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.

GRIN2C GRIN2D

2.39e-05470236309015
Pubmed

Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation.

TRPM1 GPR179

2.39e-05470222896717
Pubmed

LRIT3 is Required for Nyctalopin Expression and Normal ON and OFF Pathway Signaling in the Retina.

TRPM1 GPR179

3.98e-05570231959619
Pubmed

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.

GRIN2C GRIN2D

3.98e-05570226919761
Pubmed

Distinct distributions of five NMDA receptor channel subunit mRNAs in the brainstem.

GRIN2C GRIN2D

3.98e-0557027518475
Pubmed

Distinct spatiotemporal expressions of five NMDA receptor channel subunit mRNAs in the cerebellum.

GRIN2C GRIN2D

3.98e-0557027518474
Pubmed

Synapse-selective impairment of NMDA receptor functions in mice lacking NMDA receptor epsilon 1 or epsilon 2 subunit.

GRIN2C GRIN2D

3.98e-0557029147327
Pubmed

Neurotransmission and bipolar disorder: a systematic family-based association study.

GRIN2C GRIN2D

3.98e-05570218444252
Pubmed

Distinct gene expression of the N-methyl-D-aspartate receptor channel subunit in peripheral neurons of the mouse sensory ganglia and adrenal gland.

GRIN2C GRIN2D

3.98e-0557028015722
Pubmed

Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain.

GRIN2C GRIN2D

3.98e-05570215003177
Pubmed

cGMP-mediated signaling via cGKIalpha is required for the guidance and connectivity of sensory axons.

NTRK1 CNTN2

3.98e-05570212417579
Pubmed

GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions.

GRIN2C GRIN2D

3.98e-0557027723623
Pubmed

Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor.

GRIN2C GRIN2D

3.98e-05570212082569
Pubmed

Heterozygous deletion of NR1 subunit of the NMDA receptor alters ethanol-related behaviors and regional expression of NR2 subunits in the brain.

GRIN2C GRIN2D

3.98e-05570221945132
Pubmed

Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex.

GRIN2C GRIN2D

3.98e-05570211488959
Pubmed

Developmental changes in distribution of NMDA receptor channel subunit mRNAs.

GRIN2C GRIN2D

3.98e-0557021493227
Pubmed

The neural adhesion molecule TAG-1 modulates responses of sensory axons to diffusible guidance signals.

NTRK1 CNTN2

3.98e-05570218550718
Pubmed

N-methyl-D-aspartic acid receptor structure and function.

GRIN2C GRIN2D

3.98e-0557028036251
Pubmed

NMDA receptor activation by HIV-Tat protein is clade dependent.

GRIN2C GRIN2D

3.98e-05570219020013
Pubmed

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.

GRIN2C GRIN2D

3.98e-05570226875626
Pubmed

Differential distributions of the NMDA receptor channel subunit mRNAs in the mouse retina.

GRIN2C GRIN2D

3.98e-0557027510577
Pubmed

Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene.

GRIN2C GRIN2D

3.98e-0557028756432
Pubmed

Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins.

GRIN2C GRIN2D

3.98e-05570218233995
Pubmed

Distinct spatiotemporal distributions of the N-methyl-D-aspartate receptor channel subunit mRNAs in the mouse cervical cord.

GRIN2C GRIN2D

3.98e-0557027929904
Pubmed

Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.

MAGI1 MAGI2 GRID2IP

4.47e-053470330726710
Pubmed

A role for spermine oxidase as a mediator of reactive oxygen species production in HIV-Tat-induced neuronal toxicity.

GRIN2C GRIN2D

5.96e-05670223665428
Pubmed

Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development.

MAGI1 MAGI2

5.96e-05670215509766
Pubmed

Altered gene expression of the N-methyl-D-aspartate receptor channel subunits in Purkinje cells of the staggerer mutant mouse.

GRIN2C GRIN2D

5.96e-0567028996814
Pubmed

NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit.

GRIN2C GRIN2D

5.96e-05670215317856
Pubmed

Genotype and phenotype of 101 dutch patients with congenital stationary night blindness.

TRPM1 GPR179

5.96e-05670223714322
Pubmed

GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.

TRPM1 GPR179

5.96e-05670224790204
Pubmed

Cortical consequences of HIV-1 Tat exposure in rats are enhanced by chronic cocaine.

GRIN2C GRIN2D

5.96e-05670225760043
Pubmed

Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo.

GRIN2C GRIN2D

5.96e-0567029458051
Pubmed

Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

MAGI1 MAGI2

5.96e-0567029647693
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CCDC142 SEPHS2 MDN1 CELSR3 LRRC56 SLCO4A1 GRIN2D ATG2A ZBTB42 PLEKHH3

7.08e-051105701035748872
Pubmed

Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse.

NTRK1 BARHL2 CNTN2

7.31e-054070331152445
Pubmed

LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation.

TRPM1 GPR179

8.33e-05770225997951
Pubmed

HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.

GRIN2C GRIN2D

8.33e-05770222940423
Pubmed

Netrin 1 and Dcc signalling are required for confinement of central axons within the central nervous system.

BARHL2 CNTN2

8.33e-05770224449837
Pubmed

Early onset of NMDA receptor GluR epsilon 1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus.

GRIN2C GRIN2D

8.33e-05770212103442
Pubmed

Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures.

GRIN2C GRIN2D

8.33e-05770223267846
Pubmed

Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death.

GRIN2C GRIN2D

8.33e-05770219036954
Pubmed

A new approach to the study of haematopoietic development in the yolk sac and embryoid bodies.

SEPHS2 SLC23A3

8.33e-0577027588067
Pubmed

Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.

GRIN2C GRIN2D

8.33e-05770222833210
Pubmed

Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons.

NTRK1 CNTN2

1.11e-04870217581972
Pubmed

Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons.

GRIN2C GRIN2D

1.11e-0487028804048
Pubmed

The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid.

GRIN2C GRIN2D

1.11e-0487028845955
Pubmed

Expression of kin of irregular chiasm-like 3/mKirre in proprioceptive neurons of the dorsal root ganglia and its interaction with nephrin in muscle spindles.

KIRREL3 NTRK1

1.11e-04870218752272
Pubmed

HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons.

GRIN2C GRIN2D

1.11e-0487028563977
Pubmed

HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures.

GRIN2C GRIN2D

1.11e-0487028821747
Pubmed

Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.

GRIN2C GRIN2D

1.11e-0487027695237
Pubmed

Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.

SLCO1C1 SLCO4A1

1.11e-04870219129463
Pubmed

HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.

GRIN2C GRIN2D

1.11e-04870217360663
Pubmed

Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120.

GRIN2C GRIN2D

1.11e-0487028724036
Pubmed

Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine.

GRIN2C GRIN2D

1.11e-0487028822372
Pubmed

Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins.

MAGI1 MAGI2

1.11e-04870216316992
Pubmed

Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ß production.

GRIN2C GRIN2D

1.11e-04870221106831
Pubmed

Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures.

GRIN2C GRIN2D

1.11e-04870210448428
Pubmed

Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase.

GRIN2C GRIN2D

1.11e-0487028955056
Pubmed

Evidence of HIV type 1 glycoprotein 120 binding to recombinant N-methyl-D-aspartate receptor subunits expressed in a baculovirus system.

GRIN2C GRIN2D

1.11e-04870210555109
Pubmed

Collagen XXVII organises the pericellular matrix in the growth plate.

COL17A1 COL27A1

1.42e-04970222206015
Pubmed

The expression of thyroid hormone transporters in the human fetal cerebral cortex during early development and in N-Tera-2 neurodifferentiation.

SLCO1C1 SLCO4A1

1.42e-04970221486766
Pubmed

D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity.

GRIN2C GRIN2D

1.42e-04970222552781
Pubmed

Activation of cannabinoid type 2 receptors inhibits HIV-1 envelope glycoprotein gp120-induced synapse loss.

GRIN2C GRIN2D

1.42e-04970221670103
Pubmed

PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A.

GRIN2C GRIN2D

1.42e-0497029892651
Pubmed

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems.

GRIN2C GRIN2D

1.42e-04970217526495
Pubmed

Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS.

GRIN2C GRIN2D

1.42e-04970221491143
Pubmed

Developmental and cell type-specific expression of thyroid hormone transporters in the mouse brain and in primary brain cells.

SLCO1C1 SLCO4A1

1.42e-04970221264952
Pubmed

Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity.

GRIN2C GRIN2D

1.42e-04970216554481
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ESYT2 MDN1 SLCO4A1 DDX51 CHD4 CHD7 RFX1 CDH17

1.62e-0477470815302935
Pubmed

N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons.

GRIN2C GRIN2D

1.78e-041070219332541
Pubmed

GPR120 controls neonatal brown adipose tissue thermogenic induction.

EHHADH PLIN1

1.78e-041070231361546
Pubmed

Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase.

GRIN2C GRIN2D

2.17e-04117028581564
Pubmed

DSCAM regulates delamination of neurons in the developing midbrain.

MAGI1 MAGI2

2.17e-041170232917586
Pubmed

HIV-1 Tat-mediated apoptosis in human blood-retinal barrier-associated cells.

GRIN2C GRIN2D

2.17e-041170224739951
Pubmed

The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors.

TRPM1 GPR179

2.17e-041170228262416
Pubmed

CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins.

GRIN2C GRIN2D

2.17e-04117029647694
Pubmed

Effects of SDF-1alpha and gp120IIIB on apoptotic pathways in SK-N-SH neuroblastoma cells.

GRIN2C GRIN2D

2.17e-041170216481105
Pubmed

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.

COL4A2 NTRK1

2.17e-04117029731539
Pubmed

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties.

SLCO1C1 SLCO4A1

2.17e-041170214579113
Pubmed

C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons.

NTRK1 CNTN2

2.60e-041270219805384
Pubmed

Developmental rearrangements of cortical glutamate-NMDA receptor binding sites in late human gestation.

GRIN2C GRIN2D

2.60e-04127028665664
Pubmed

Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle.

GRIN2C GRIN2D

2.60e-041270212815021
Pubmed

Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102.

GRIN2C GRIN2D

2.60e-041270211937501
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2C GRIN2D

1.50e-0474921201
GeneFamilyCollagens

COL4A2 COL17A1 COL27A1

2.62e-0446493490
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

MAGI1 MAGI2

2.24e-0326492904
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

PLEKHF2 PLEKHF1

3.18e-033149281
GeneFamilyPDZ domain containing

MAGI1 MAGI2 GRID2IP

8.09e-031524931220
ToppCellwk_20-22-Hematologic-Meg-ery-Platelet|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LANCL3 AMHR2 ABCC4 PLEKHF2 RIPOR3 INKA2

4.13e-07181706724efbc200e8388829bc7d81830c2689a95fa838
ToppCellmoderate-Myeloid-Mast_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

AMHR2 ABCC4 BMP2K NTRK1 GRIN2C

8.29e-06175705bbd2971bc6d69e507f90a637834d0936c205c590
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LANCL3 SLCO1C1 COL27A1 PLIN1 GPR179

8.29e-06175705f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LANCL3 SLCO1C1 COL27A1 PLIN1 GPR179

8.29e-061757057bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR91 BMP2K COL27A1 CHD7 LOXL3

8.52e-0617670524b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 GRIN2C GRIN2D INPP5J

8.52e-0617670595d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 GRIN2C GRIN2D INPP5J

9.25e-061797053b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM132C COL4A2 NTRK1 COL27A1 SVEP1

9.76e-06181705ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Htra1)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GRIN2C PLIN1 AQP9 GPR179

1.04e-0586704c6c0e8e562ffc705e0cd3f503a9e43ca2669e9b0
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Htra1)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GRIN2C PLIN1 AQP9 GPR179

1.04e-0586704c1181a7e9f4cbde5a3bee7b54d6448dfce58b238
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Htra1)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GRIN2C PLIN1 AQP9 GPR179

1.04e-05867044263673abf183f2e04f1a2bf37e365a25b8cb0b4
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TMEM132C COL4A2 MAGI2 RIPOR3 SVEP1

1.33e-05193705261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellhematopoetic_progenitors-CD34+_MEP_1|hematopoetic_progenitors / Lineage and Cell class

AMHR2 ABCC4 BMP2K NTRK1 RIPOR3

1.47e-051977056172a1b98ff840d9174b1ab20ba0c202a7ef87af
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

DNHD1 BMP2K EHHADH EPX INPP5J

1.47e-0519770515b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

DNHD1 BMP2K EHHADH EPX INPP5J

1.47e-05197705a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

AMHR2 NTRK1 CD55 EPX AQP9

1.54e-05199705a24a319d3ba8f4759f742af27610b4d62e359a2d
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3|Neuronal / cells hierarchy compared to all cells using T-Statistic

TMEM132C COL4A2 GRIN2C GRIN2D INPP5J

1.58e-052007052441a36d363b799a4692aa697f969cda056c2d60
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)|Neuronal / cells hierarchy compared to all cells using T-Statistic

TMEM132C MAGI1 MAGI2 GRIN2D INPP5J

1.58e-052007051276bfa911fddada4235e12e3081baa53164574b
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3-|Neuronal / cells hierarchy compared to all cells using T-Statistic

TMEM132C COL4A2 GRIN2C GRIN2D INPP5J

1.58e-05200705c7bca638229bd4fd2414171e73fa949e36a10a92
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3--L2-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

TMEM132C COL4A2 GRIN2C GRIN2D INPP5J

1.58e-05200705d841dbe2297c3bf62f49bae5921662cd6a47e5c2
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMEM132C LANCL3 GRIN2D INPP5J

4.66e-0512670484dce108561d4b745d19250c2ac0667d9e4ea17d
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-2|TCGA-Brain / Sample_Type by Project: Shred V9

GRID2IP COL17A1 CELSR3 GPR179

4.81e-05127704018ffd9ff1913787cb0086a8581b399a121eaba1
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c3-LAMP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNHD1 TRPM1 DNAH9 SLC23A3

6.83e-05139704bb2b020dda32ddc60ec9952de5b01acee60b5b59
ToppCellICU-SEP-Lymphocyte-T_NK-Treg|ICU-SEP / Disease, Lineage and Cell Type

FSIP2 MAGI1 LRRC56 SLCO4A1

8.04e-05145704ee99b58462f955b96d036aa67e343db047d66f64
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TMEM132C LANCL3 GRIN2D INPP5J

8.04e-051457048b13b576fd2e6e33ccb146860a91a53cee0cdd4d
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l8|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GARIN1A PERM1 CHD7 AQP9

1.09e-041577045098675f64342c41c5ca3551b24962d10c83e64d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNHD1 GRIN2C SVEP1 SHQ1

1.12e-041587047f5426585d0d299d2b48e5fcb349950feffdef33
ToppCellBronchial_Brush-Epithelial-Goblet_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A2 LANCL3 SEPHS2 PERM1

1.15e-0415970495834b767cfb4fb8c5aeea89c10f3e14a1fd15c1
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM132C AMHR2 GRIN2C INKA2

1.21e-041617041f4614ae15bd2fc08e555cea4d0152c4a940d048
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 FOXO6 RIPOR3 SVEP1

1.23e-0416270468c40d12689cc1b6c797e6e48173f0110f8144e4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 FOXO6 RIPOR3 SVEP1

1.23e-04162704735fa3f77b31a4189e431d05c326403c18cbbffb
ToppCelldroplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR91 GARIN1A BMP2K LOXL3

1.29e-0416470478de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCellmoderate-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

AMHR2 ABCC4 NTRK1 GRIN2C

1.36e-04166704c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLCO1C1 COL27A1 RIPOR3 SVEP1

1.42e-04168704d19a115365c5415e51c039718d7669de788fcf33
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil-promyelocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL17A1 INPP5J INKA2 NOS1AP

1.45e-04169704f33f4a0baad1b3cb5be61dfc7b00c7a3845f7120
ToppCellwk_20-22-Hematologic-Meg-ery-Megakaryocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LANCL3 ABCC4 RIPOR3 INKA2

1.49e-04170704eace4dd09cdbde0fa40a6aa0f3dba1114d0ce475
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FSIP2 MAGI2 KIRREL3 RIPOR3

1.49e-041707045d5f208682be21ed58320f5fc083a7898f8712da
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIRREL3 RP1L1 FAM167A SLCO4A1

1.49e-0417070417bd7fd25a2657cb536ad47e294332920f759e95
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Col27a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCC4 FOXO6 COL27A1 INKA2

1.52e-04171704d07e2c5f7d7f12c68860d4161d76372de174f1d8
ToppCellAT1_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 MAGI1 FAM167A CD55

1.59e-041737043afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AMHR2 ABCC4 BMP2K NTRK1

1.59e-04173704a7dee23b1d43d3070d502487af319ff81a9a747b
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-eo/baso/mast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

AMHR2 NTRK1 GRIN2C EPX

1.62e-0417470464d13a7a9757e85f4f4af876c687dd18a7efa01a
ToppCell10x3'2.3-week_17-19-Lymphocytic_T-T_NK-Treg|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FSIP2 EHHADH PLEKHF1 LTA

1.62e-041747047ca39c9ecd609e5ade30dac1a948a4a4fff1b3b2
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 LANCL3 KIRREL3

1.66e-04175704955f10982a487e12cdc3a9f80b3be06bf6c59de7
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 GRIN2D INPP5J

1.66e-041757049d797888edb39fd12fd9cfc698a42b7bed19a5b5
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 ABCC4 GPR179 NOS1AP

1.70e-041767043bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellAT1_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 MAGI1 FAM167A CD55

1.73e-041777043128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDR91 COL27A1 CHD7 LOXL3

1.73e-04177704f360f7099570d248531897b96e0de282e58f59e9
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF11 FAM167A CD55 SHQ1

1.73e-04177704c2b8a3a149d70f77612759dea34df9e43953c566
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

TMEM132C COL4A2 PLIN1 SVEP1

1.73e-04177704f0edf04930692418953e4f00a917257804ec0ffd
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF11 FAM167A CD55 SHQ1

1.73e-04177704384f841aa7b2d05815af7885e481f5affc55d897
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAGI2 SEPHS2 COL17A1 LOXL3

1.73e-0417770430f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellfacs-Thymus-Epithelium-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF11 FAM167A CD55 SHQ1

1.73e-041777040e9e44119653abfd270e602e5e477a15e774638f
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

TMEM132C COL4A2 PLIN1 SVEP1

1.77e-04178704278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 GRIN2D INPP5J

1.81e-04179704d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 MAGI2 ABCC4 RIPOR3

1.81e-04179704a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132C MAGI2 COL27A1 SVEP1

1.85e-0418070408ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 LOXL3 INKA2 PLEKHH3

1.85e-04180704f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 LOXL3 INKA2 PLEKHH3

1.85e-04180704dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AMHR2 ABCC4 BMP2K NTRK1

1.85e-041807042658a6be43d6d94767b4fc5af2d8632469a8a979
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 CHRD INPP5J

1.89e-04181704bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 GRIN2C INPP5J

1.89e-04181704153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 ABCC4 CD55 NOS1AP

1.89e-04181704576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LANCL3 NTRK1 PLEKHF2 EPX

1.89e-04181704338c7362d258a87f1a6b1a65376f5394d4b2b4b2
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 GRIN2D INPP5J

1.93e-0418270408aff7112c9dac0ef5540300516a604782b21169
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C CHRD GRIN2D INPP5J

1.97e-04183704d2074b13b4831ec18c81273d9a1ff673c3f6a16d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 CHRD INPP5J

1.97e-0418370404d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 GRIN2D INPP5J

1.97e-041837045a541a7f6c3514be8a13e988185dfe388c874f8b
ToppCell3'_v3-lymph-node_spleen-Mast|lymph-node_spleen / Manually curated celltypes from each tissue

AMHR2 BMP2K NTRK1 NOS1AP

2.01e-0418470483675c7a083c52fb74dc8b9d35df0ef69715f707
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 GRIN2D INPP5J

2.01e-041847042ba98708dfd7f1b2a661578a334684094ff453ad
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAGI2 AMHR2 BMP2K NTRK1

2.01e-0418470416ba6822570b1017b8f24d9439b4fbdaaeecf7aa
ToppCellIPF-Myeloid-Mast|World / Disease state, Lineage and Cell class

AMHR2 ABCC4 BMP2K NTRK1

2.01e-041847047aefa182acad5a53c730945fec85329d7168606a
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

TMEM132C CHRD RIPOR3 SVEP1

2.01e-041847042b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell3'_v3-lymph-node_spleen-Mast-Mast_cells|lymph-node_spleen / Manually curated celltypes from each tissue

AMHR2 BMP2K NTRK1 NOS1AP

2.01e-04184704ed266bd2d12f86e8786473e64fbcd58319cd4c2a
ToppCellIPF-Myeloid-Mast|IPF / Disease state, Lineage and Cell class

AMHR2 ABCC4 BMP2K NTRK1

2.01e-04184704c3baf21f10b45cf91ac99997a59f353bcf3de8b7
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 MAGI1 CD55 NOS1AP

2.05e-041857041c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM132C FAM167A CD55 CHRD

2.05e-04185704d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 CHRD INPP5J

2.10e-04186704948815663c212c4311329d503b5991cbbbff9808
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BARHL2 CHD7 GRIN2C SVEP1

2.10e-04186704d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 GRIN2C EPX INPP5J

2.10e-04186704337f768cc43db2db96ba6495b076006b1a5b0331
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 GRIN2C EPX INPP5J

2.10e-04186704e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMHR2 ABCC4 BMP2K NTRK1

2.14e-04187704bdcef4f3e093c3646b639a189bbe93d6f4c40f3c
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMHR2 ABCC4 BMP2K NTRK1

2.14e-0418770409348f1e8bbbca8dca885461937b9b1dd248b034
ToppCellCF|World / Disease state, Lineage and Cell class

CD55 SLCO4A1 ATG2A AQP9

2.14e-04187704eec4d4e4a658e3a61c05745167a1a5e3d39bb43e
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMHR2 ABCC4 BMP2K NTRK1

2.14e-041877040f7a42c55997e34a0d20e492e16b03e91e965335
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMHR2 ABCC4 BMP2K NTRK1

2.14e-04187704064730fa72f8637c3db3fc34d2e363d2b9a38f1d
ToppCell10x5'-Lung-Mast|Lung / Manually curated celltypes from each tissue

MAGI2 AMHR2 ABCC4 NTRK1

2.14e-04187704f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A2 COL27A1 RIPOR3 SVEP1

2.14e-0418770476bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell10x5'-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

MAGI2 AMHR2 ABCC4 NTRK1

2.14e-04187704da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

ABCC4 BMP2K EHHADH COL27A1

2.14e-04187704d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 MAGI1 CD55 NOS1AP

2.14e-04187704d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BARHL2 CHD7 GRIN2C SVEP1

2.14e-041877041b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TMEM132C COL4A2 MAGI2 COL27A1

2.14e-04187704c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellfacs-Lung-24m-Hematologic-myeloid-leukocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLCO4A1 ECT2 AQP9 SHQ1

2.18e-0418870461b6047affa18c5e71210fcce449e2bbe7cf141b
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 ESYT2 ABCC4 SLCO1C1

2.18e-041887044dc89c7843ebd078e3414e835c56f11fa27f0c5f
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 ESYT2 ABCC4 SLCO1C1

2.18e-04188704d577b3c2a844e3062c7ca9e9ebc1722d0ac95caa
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 ESYT2 ABCC4 SLCO1C1

2.18e-041887041e788b60dd643bf220d8dfafa82d85fd083cbc71
ToppCellfacs-Lung-24m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLCO4A1 ECT2 AQP9 SHQ1

2.18e-04188704797ce39602f0f78081eb44a21da0d9443f7fd9cf
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM132C COL4A2 GRIN2D INPP5J

2.18e-041887048de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMHR2 ABCC4 BMP2K NTRK1

2.23e-04189704aba941ba6ce7702418b3f470bde573d123c4aade
DiseaseMAJOR AFFECTIVE DISORDER 2

MAGI1 MAGI2 CDH17

7.78e-0617683C1839839
DiseaseSchizophrenia

MAGI1 MAGI2 NTRK1 LTA CHD4 TRPM1 GRIN2C GRIN2D NOS1AP SLC23A3

3.31e-058836810C0036341
Diseasecoronary artery calcification

COL4A2 FSIP2 MAGI1 MAGI2 FAM167A AQP9 SHQ1

7.96e-05450687EFO_0004723
DiseaseX-Linked Csnb

TRPM1 GPR179

3.40e-0412682C3711543
DiseaseNight blindness, congenital stationary, type 1

TRPM1 GPR179

3.40e-0412682C3501847
DiseaseMethionine sulfoxide measurement

TMEM132C SLC23A3

3.40e-0412682EFO_0021650
DiseaseNight Blindness, Congenital Stationary, Type 1A

TRPM1 GPR179

3.40e-0412682C3495587
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)

TRPM1 GPR179

3.40e-0412682C1864877
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A

TRPM1 GPR179

3.40e-0412682C1848172
Diseaseage of onset of multiple sclerosis

LRRC56 CDH17

3.40e-0412682OBA_2001029
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B

TRPM1 GPR179

3.40e-0412682C1850362
DiseaseCone-rod synaptic disorder, congenital nonprogressive

TRPM1 GPR179

4.02e-0413682C4041558
Diseasesevere acute respiratory syndrome, COVID-19

TMEM132C COL4A2 MAGI1 MAGI2 KIRREL3 TRPM1

5.79e-04447686EFO_0000694, MONDO_0100096
DiseaseNight blindness, congenital stationary

TRPM1 GPR179

6.96e-0417682C0339535
Diseasepulmonary embolism

MAGI1 ABCC4

1.52e-0325682EFO_0003827

Protein segments in the cluster

PeptideGeneStartEntry
IPVVGPLVGAVIGGL

AQP9

246

O43315
PVGLQGLRGEVGLPG

COL17A1

681

Q9UMD9
PGGVLSVELPGLLAQ

ESYT2

101

A0FGR8
GDIGDTINLPGRPGL

COL4A2

1091

P08572
GAVLRIGPGETLEPL

CCDC142

151

Q17RM4
GAGGEEVKLQGPLPL

DNHD1

1426

Q96M86
GALRPGNGPEILLGQ

BMP2K

411

Q9NSY1
PGVGLGDPQAIQERL

CHD7

481

Q9P2D1
GLTGAVGGVIRQLPP

ATG2A

1881

Q2TAZ0
GGPGRLLSGPLLVLE

AMHR2

266

Q16671
PLEEEGQRGGPILAP

ECT2

481

Q9H8V3
DVAPGPLGLGQLLAV

NTRK1

616

P04629
HEGRVEVQIGGPGPL

LOXL3

426

P58215
EVQIGGPGPLRWGLI

LOXL3

431

P58215
PLLENGELLIPGRGD

MDN1

416

Q9NU22
GPRLGEGELLLEVQG

MAGI1

61

Q96QZ7
RILGGDEPGQPILIG

MAGI2

791

Q86UL8
ALEQLEISGGGPVPG

INKA2

51

Q9NTI7
LEGVRELQGPSGLEP

GPR179

2306

Q6PRD1
LPLGGLLNQGPGLEE

FER1L4

1086

A9Z1Z3
PGEIRNGQIDVPGGI

CD55

166

P08174
AGVGPAQLLDLPLGV

FSIP2

41

Q5CZC0
RPGVLGIVPLQGQGE

CORO7

51

P57737
AQPEILIGTIPGAGG

ECHS1

161

P30084
GLPEVTLGLLPGARG

EHHADH

121

Q08426
IGAIAEPLLPGARVG

EPX

616

P11678
GELPRLAELGGPLGL

FOXO6

296

A8MYZ6
ERILQELPPLGGGAE

LANCL3

36

Q6ZV70
VLLLPPAGGDELQGI

MMAA

261

Q8IVH4
EVAALPGPRGLLGGV

PLIN1

321

O60240
RPGELLAVVGPVGAG

ABCC4

436

O15439
GGLRPGDQILEVEGL

GRID2IP

41

A4D2P6
EEAAGPLVPGLVLGG

DDX51

151

Q8N8A6
LVQIRTTGPGGDGIP

CNTN2

981

Q02246
PGEQGLIGQRGEPGL

COL27A1

1176

Q8IZC6
LVPRVLIHGLGPGGQ

BARHL2

356

Q9NY43
GGAERGLLGLEPVPS

KLF11

151

O14901
VILGGPVISLRAGDP

KIRREL3

151

Q8IZU9
LAIRPGLEVGPESGL

DNAH9

81

Q9NYC9
PPAQGEALLGGLELI

NOS1AP

441

O75052
PGLGVREPIFVGLRG

CELSR3

76

Q9NYQ7
GVPAVLLGLAVGLDP

CELSR3

2651

Q9NYQ7
INDGGRPPLEGIVSL

CDH17

746

Q12864
PPLLARVGGNIEVLG

CHD4

1401

Q14839
GEDRLEGVLGPAVPL

PERM1

666

Q5SV97
GRGLVILEPLLAGEP

LRRC43

566

Q8N309
GQPLTIPGRVLIGEG

PLEKHF2

26

Q9H8W4
LEEGERGGQEPLLPL

FAM167A

71

Q96KS9
VREPGPGVELGVENG

GARIN1A

11

Q6NXP2
GQPLALPGRVLLGEG

PLEKHF1

26

Q96S99
GGGRGPLEVTLTQPV

PLEKHH3

51

Q7Z736
PVVVAEGEGQGPLIR

TMEM132C

756

Q8N3T6
GPGLGDGVAAVPVLR

LRRC56

486

Q8IYG6
LQGKVLPEGVGPGDI

RFX1

591

P22670
PLGVSGPLIEELGEQ

SHQ1

531

Q6PI26
VGLPIPGGGALVLGQ

SVEP1

1541

Q4LDE5
IPGTQLERGLGQGLP

SLC23A3

511

Q6PIS1
VVRILGGIPGPIAFG

SLCO4A1

621

Q96BD0
ILTLEGPPQQGVGGI

CHRD

286

Q9H2X0
LPALRLETVDPGGGG

INPP5J

961

Q15735
AGGPGLQEPLQLGEL

VPS52

31

Q8N1B4
LVLLPGAQGLPGVGL

LTA

26

P01374
VRPPLGRGLVGGQEE

SEPHS2

81

Q99611
GGLLPGAGLPEEQII

RIPOR3

746

Q96MK2
LVLQVGRPEQGAVGP

RP1L1

806

Q8IWN7
LRGIGETPIQPLGIA

SLCO1C1

196

Q9NYB5
GVPLVGLVVEGGPNV

TRPM1

246

Q7Z4N2
GLVVGLQPLPLSGEG

ZBTB42

256

B2RXF5
EGGGVRPEQPFIVLG

WDR91

386

A4D1P6
QLRGTGLQPGEEELP

USP5

601

P45974
LDVVTLELGPGGPRA

GRIN2C

196

Q14957
GPIEPQGLGLGLGEA

GRIN2D

966

O15399