Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondynein light chain binding

BSN DYNC1I2

3.99e-0412502GO:0045503
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

MAN2A1 HYAL3 SI SMPD1

4.62e-04144504GO:0016798
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1D1 AKR1A1

5.49e-0414502GO:0004032
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1D1 AKR1A1

2.07e-0327502GO:0008106
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

MAN2A1 HYAL3 SI

2.19e-03103503GO:0004553
GeneOntologyMolecularFunctionphospholipase C activity

SMPD1 PLCG1

2.39e-0329502GO:0004629
DomainALDOKETO_REDUCTASE_1

AKR1D1 AKR1A1

3.24e-0410512PS00798
DomainAldo/ket_reductase_CS

AKR1D1 AKR1A1

3.24e-0410512IPR018170
DomainAldo/keto_reductase

AKR1D1 AKR1A1

3.24e-0410512IPR020471
DomainPhosphodiest

ENPP5 PIGO

3.24e-0410512PF01663
DomainALDOKETO_REDUCTASE_2

AKR1D1 AKR1A1

3.24e-0410512PS00062
DomainALDOKETO_REDUCTASE_3

AKR1D1 AKR1A1

3.24e-0410512PS00063
DomainPhosphodiest/P_Trfase

ENPP5 PIGO

3.24e-0410512IPR002591
Domain-

AKR1D1 AKR1A1

8.56e-04165123.20.20.100
DomainGal_mutarotase_SF_dom

MAN2A1 SI

9.68e-0417512IPR011013
DomainNADP_OxRdtase_dom

AKR1D1 AKR1A1

9.68e-0417512IPR023210
DomainAldo_ket_red

AKR1D1 AKR1A1

9.68e-0417512PF00248
DomainAldo/ket_red/Kv-b

AKR1D1 AKR1A1

9.68e-0417512IPR001395
Domain-

ACACA ACLY

1.09e-03185123.30.470.20
DomainATP_grasp_subdomain_2

ACACA ACLY

3.23e-0331512IPR013816
DomainAlkaline_phosphatase_core

ENPP5 PIGO

3.23e-0331512IPR017850
DomainAlkaline_Pase-like_a/b/a

ENPP5 PIGO

3.23e-0331512IPR017849
Domain-

ENPP5 PIGO

3.23e-03315123.40.720.10
DomainEGF_2

EPHB2 ADAM20 HYAL3 LAMB1

5.87e-03265514PS01186
DomainZnf_FYVE_PHD

KDM4C WDFY3 BSN

7.55e-03147513IPR011011
Pubmed

Genes for the neuronal immunoglobulin domain cell adhesion molecules neurofascin and Nr-CAM map to mouse chromosomes 1 and 12 and homologous human chromosomes.

LAMB1 PAM NFASC

1.04e-0775138672144
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KDM4C ESYT1 NFASC DDHD2 FAM131B

3.95e-071015159872452
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

EPHB2 XYLT2 MAN2A1 ACLY ESYT1 HYAL3 LAMB1 PAM SMPD1 FGFR4 PIGO

1.07e-061201511135696571
Pubmed

Signal transduction by fibroblast growth factor receptor-4 (FGFR-4). Comparison with FGFR-1.

PLCG1 FGFR4

2.11e-0625127518429
Pubmed

Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1.

NPHS1 PLCG1

2.11e-06251219179337
Pubmed

Polymorphisms, de novo lipogenesis, and plasma triglyceride response following fish oil supplementation.

ACACA ACLY

2.11e-06251223886516
Pubmed

Secretion of three enzymes for fatty acid synthesis into mouse milk in association with fat globules, and rapid decrease of the secreted enzymes by treatment with rapamycin.

ACACA ACLY

6.32e-06351221281598
Pubmed

The lipogenesis pathway as a cancer target.

ACACA ACLY

6.32e-06351221726077
Pubmed

ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate.

ACACA ACLY

6.32e-06351226452058
Pubmed

Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.

ACACA ACLY

2.10e-05551237163372
Pubmed

Distinct profile of HIF1α, PTCH, EphB2, or DNA repair protein expression and BRAF mutation in colorectal serrated adenoma.

EPHB2 PTCH1

2.10e-05551224612059
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

TRHDE PCBP3 MAN2A1 ACLY PAM SI SMPD1 AKR1A1 MPI

2.27e-05107051923533145
Pubmed

Animal models of lysosomal disease: an overview.

SMPD1 DYNC1I2

3.15e-0565129728334
Pubmed

A novel transgenic mouse model of lysosomal storage disorder.

ACACA ACLY

3.15e-05651227659423
Pubmed

Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region.

EPHB2 PLCG1

4.41e-0575129632142
Pubmed

EphB regulates L1 phosphorylation during retinocollicular mapping.

EPHB2 NFASC

4.41e-05751222579729
Pubmed

Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.

KCNJ6 BSN

5.87e-05851219567891
Pubmed

Chemerin, a novel adipokine in the regulation of angiogenesis.

TRHDE PTCH1

5.87e-05851220237162
Pubmed

Proteomic analysis of in vivo phosphorylated synaptic proteins.

NFASC BSN FAM131B

6.61e-055351315572359
Pubmed

Control of skeletal patterning by ephrinB1-EphB interactions.

EPHB2 PTCH1

7.54e-05951212919674
Pubmed

Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin.

NPHS1 LAMB1

1.15e-041151211435469
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SZT2 CCSER2 NFASC BSN NDRG4 URGCP

1.21e-0452951614621295
Pubmed

FGF signaling is required for anterior but not posterior specification of the murine liver bud.

EPHB2 FGFR4

1.38e-041251225302779
Pubmed

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.

NPHS1 PTCH1

1.63e-041351221406566
Pubmed

A "double adaptor" method for improved shotgun library construction.

ACD CCSER2 PAM NFASC WDFY3 NDRG4

1.89e-045745168619474
Pubmed

GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH.

ACLY UCHL3

2.19e-041551231417184
Pubmed

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

LAMB1 BSN

2.83e-041751219915572
Pubmed

FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate.

PLCG1 FGFR4

2.83e-041751229342370
Pubmed

Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus.

NPHS1 LAMB1

2.83e-041751218082680
Pubmed

A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.

ACACA ACLY UCHL3

2.99e-048851327182664
Pubmed

Epithelial hedgehog signals pattern the intestinal crypt-villus axis.

EPHB2 PTCH1

3.18e-041851215590741
Pubmed

SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression.

ACACA PTCH1

3.55e-041951226685326
Pubmed

Tbx1 regulates oral epithelial adhesion and palatal development.

EPHB2 PTCH1

3.94e-042051222371266
Pubmed

The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex.

EPHB2 LAMB1 PAM

4.10e-049851319554387
Pubmed

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.

GNPDA1 SETD1B ACD PAM NDRG4

4.20e-0443151533660365
Pubmed

Control of TurboID-dependent biotinylation intensity in proximity ligation screens.

MAN2A1 HYAL3 PIGO

4.35e-0410051336966971
Pubmed

Phospholipase C-gamma as a signal-transducing element.

PLCG1 FGFR4

4.35e-042151210579907
Pubmed

Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb.

EPHB2 PTCH1

4.78e-042251215030763
Pubmed

The transcription regulator Lmo3 is required for the development of medial ganglionic eminence derived neurons in the external globus pallidus.

BSN PTCH1

4.78e-042251237532091
Pubmed

Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice.

EPHB2 PTCH1

4.78e-042251228027321
Pubmed

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

MED18 AKR1A1 DDHD2

5.15e-0410651331024071
Pubmed

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.

ADAM20 PTCH1

5.23e-042351230814516
Pubmed

Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.

ACACA ACLY

5.23e-042351226508642
Pubmed

ATP-citrate lyase deficiency in the mouse.

ACACA ACLY

5.23e-042351214662765
Pubmed

FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum.

FGFR4 PTCH1

6.19e-042551224983448
Pubmed

siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors.

ACACA TREX2

6.70e-042651223435420
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

BUD23 SETD1B ACACA ACLY ESYT1 PLCG1 WDFY3 DYNC1I2

7.38e-04135351829467282
Pubmed

Biosynthesis of triacylglycerols.

ACACA ACLY

7.78e-04285128944226
Pubmed

Extra-embryonic vasculature development is regulated by the transcription factor HAND1.

EPHB2 PTCH1

7.78e-042851215073150
Pubmed

Primary cilia and Gli3 activity regulate cerebral cortical size.

EPHB2 PTCH1

8.35e-042951221976438
Pubmed

Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation.

EPHB2 SI

8.35e-042951216230531
Pubmed

Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.

FGFR4 PTCH1

9.54e-043151222076636
Pubmed

Crk proteins transduce FGF signaling to promote lens fiber cell elongation.

EPHB2 FGFR4

9.54e-043151229360039
Pubmed

Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform.

TRHDE FGFR4

9.54e-043151216123981
Pubmed

Expression of early developmental markers predicts the efficiency of embryonic stem cell differentiation into midbrain dopaminergic neurons.

KCNJ6 PTCH1

9.54e-043151222889265
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SETD1B ACACA SZT2 ESYT1 PLCG1 WDFY3 PTCH1

1.10e-03110551735748872
Pubmed

14-3-3ζ coordinates adipogenesis of visceral fat.

ACACA ACLY

1.15e-033451226220403
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

PCBP3 MAN2A1 ACACA ACLY ESYT1 LAMB1 PAM PIGO

1.16e-03145151830550785
Pubmed

Multiple roles of epithelial heparan sulfate in stomach morphogenesis.

EPHB2 PTCH1

1.22e-033551229700203
Pubmed

The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation.

ACACA ACLY

1.36e-033751235863637
Pubmed

Large-scale concatenation cDNA sequencing.

ACD PAM NFASC WDFY3 NDRG4

1.44e-035685159110174
CytobandEnsembl 112 genes in cytogenetic band chr5q21

MAN2A1 PAM

2.71e-0369512chr5q21
GeneFamilyAldo-keto reductases

AKR1D1 AKR1A1

2.57e-0415292399
GeneFamilyFibronectin type III domain containing

EPHB2 NPHS1 NFASC

2.10e-03160293555
GeneFamilySterile alpha motif domain containing

EPHB2 DDHD2

8.73e-0388292760
CoexpressionKIM_ALL_DISORDERS_DURATION_CORR_DN

GNPDA1 ACD ESYT1 AKR1A1 PAK6

9.25e-06145515M2113
CoexpressionPRC2_EZH2_UP.V1_UP

EPHB2 PCBP3 MAN2A1 HYAL3 ORAI2

3.58e-05192515M2739
CoexpressionGSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_UP

EPHB2 ESYT1 PAM PLCG1 BSN

4.14e-05198515M8377
CoexpressionGSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_UP

NPHS1 SZT2 UCHL3 CCSER2 AKR1A1

4.14e-05198515M4309
CoexpressionGSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_DN

PCBP3 ACLY NEXMIF PAM MPI

4.35e-05200515M8962
CoexpressionHALLMARK_GLYCOLYSIS

XYLT2 GNPDA1 PAM AKR1A1 MPI

4.35e-05200515M5937
CoexpressionGSE360_L_DONOVANI_VS_L_MAJOR_DC_UP

ACLY CCSER2 WDFY3 DDHD2 FAM131B

4.35e-05200515M5192
CoexpressionKIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP

GNPDA1 ACD ESYT1 PAM AKR1A1 DDHD2 PAK6 BSN

9.72e-05755518M2105
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRHDE PKNOX2 LAMB1 NFASC FGFR4

2.76e-06193515b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE PKNOX2 LAMB1 NFASC FGFR4

3.28e-06200515e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE PKNOX2 LAMB1 NFASC FGFR4

3.28e-06200515311fab076f2ceb258e3970eb21e39344b894042a
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE PKNOX2 LAMB1 NFASC FGFR4

3.28e-0620051534f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRHDE NEXMIF CCSER2 PLCG1

3.46e-051615145fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell367C-Fibroblasts-Fibroblast-G-|367C / Donor, Lineage, Cell class and subclass (all cells)

PCBP3 FGFR4 PAK6 PTCH1

4.09e-05168514b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell367C-Fibroblasts-Fibroblast-G|367C / Donor, Lineage, Cell class and subclass (all cells)

PCBP3 FGFR4 PAK6 PTCH1

4.09e-051685148c95093b1ea45826f62893edd3c410fe53b563a4
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SZT2 ESYT1 CCSER2 PTCH1

4.28e-0517051455fe16d98ea284d05fb899888e4569c685644c7b
ToppCellThalamus-Neuronal-Excitatory|Thalamus / BrainAtlas - Mouse McCarroll V32

TEX15 BSN ORAI2 NDRG4

4.90e-05176514d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell10x3'2.3-week_17-19-Lymphocytic_T-T_NK-NK_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CCSER2 SMPD1 PLCG1 PTCH1

5.12e-05178514a34bb693b72684cbd97ac9efff77d2d14e41be75
ToppCellwk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PCBP3 NEXMIF NFASC BSN

5.23e-05179514e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKNOX2 KCNJ6 LAMB1 TREX2

5.23e-05179514dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 LAMB1 PAM NDRG4

5.95e-0518551440e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 LAMB1 PAM NDRG4

5.95e-051855145f2eeba80aff145e85cfd81e2890a155406badb9
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 LAMB1 PAM NDRG4

5.95e-05185514f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PKNOX2 PCBP3 LAMB1 PAM

5.95e-05185514a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

TRHDE PKNOX2 LAMB1 NFASC

6.20e-0518751492d468dde81125d51daf7abd4703741abe1ab91c
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRHDE PKNOX2 LAMB1 PTCH1

6.46e-051895142a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellwk_20-22-Hematologic-Myeloid-APOE+_Mac1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

XYLT2 GNPDA1 HYAL3 AKR1A1

6.73e-05191514c204ec71b7755b46a18d3a6aa84d0f407145ce9d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 TRHDE LAMB1 DNAH7

6.73e-05191514d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PKNOX2 LAMB1 NFASC FGFR4

6.73e-051915146688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PKNOX2 LAMB1 NFASC FGFR4

6.87e-0519251499ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KCNJ6 PAK6 BSN NDRG4

7.01e-05193514b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 TRHDE LAMB1 DNAH7

7.01e-05193514ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

TRHDE PKNOX2 LAMB1 FGFR4

7.01e-05193514acad568621ed677031797b8c2e34dafea798d681
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRHDE PKNOX2 LAMB1 FGFR4

7.01e-0519351499525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

PKNOX2 LAMB1 NFASC FGFR4

7.01e-05193514ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PKNOX2 LAMB1 FGFR4 PTCH1

7.15e-0519451435f132cc38ac133be01834ed0946188aa0757eb4
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRHDE PKNOX2 LAMB1 FGFR4

7.15e-05194514e93de9428c986b8943fc169258847c650cfab0e5
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TRHDE PKNOX2 LAMB1 FGFR4

7.15e-05194514011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKNOX2 KCNJ6 LAMB1 FGFR4

7.15e-051945148f19e553f18c313c2a2ff9453884b9484b255d71
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKNOX2 KCNJ6 LAMB1 FGFR4

7.15e-0519451467fbb81b7d20cb63be27b2a2beea5b5689f8e08c
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

PKNOX2 LAMB1 NFASC FGFR4

7.29e-0519551461c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

TRHDE PKNOX2 LAMB1 NFASC

7.29e-05195514603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

PKNOX2 LAMB1 NFASC FGFR4

7.29e-05195514aa0add081881d349099d12efca5cdee098038d4e
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 NFASC SMPD1 PTCH1

7.58e-051975146806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCBP3 KCNJ6 NFASC NDRG4

7.73e-0519851485881637641d8996be2edc65c4bceff0433135e7
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

PKNOX2 LAMB1 NFASC FGFR4

7.73e-0519851426e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

PKNOX2 LAMB1 PTCH1 PIGO

7.73e-051985140c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE PKNOX2 LAMB1 NFASC

8.04e-05200514cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

TRHDE LAMB1 TEX15 PTCH1

8.04e-0520051464ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRHDE PKNOX2 LAMB1 NFASC

8.04e-05200514389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts|Control_saline / Treatment groups by lineage, cell group, cell type

TRHDE LAMB1 TEX15 PTCH1

8.04e-05200514a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

TRHDE LAMB1 TEX15 PTCH1

8.04e-05200514bd8cf33502adea320e91ca2af14e1911d88ad374
DrugDiphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; PC3; HT_HG-U133A

EPHB2 PCBP3 SZT2 PLCG1 FGFR4 PTCH1 DNAH7

2.64e-071965173743_DN
DrugBetaine

ACACA ACLY UCHL3 LAMB1 AKR1A1 NDRG4

1.36e-06157516ctd:D001622
DrugBumetanide [28395-03-1]; Down 200; 11uM; PC3; HT_HG-U133A

MED18 SMPD1 PLCG1 FGFR4 ORAI2 PIGO

4.78e-061955165117_DN
DrugIsosorbide dinitrate [87-33-2]; Down 200; 17uM; MCF7; HT_HG-U133A

EPHB2 SZT2 PLCG1 ORAI2 NDRG4 PIGO

4.78e-061955164742_DN
DrugBetazole hydrochloride; Down 200; 27uM; PC3; HT_HG-U133A

KDM4C WDFY3 NDRG4 PIGO URGCP MPI

4.92e-061965166344_DN
Drugspiromesifen

ACACA BSN

4.92e-062512CID009907412
DrugReserpinic acid hydrochloride; Down 200; 9.2uM; PC3; HT_HG-U133A

SZT2 PLCG1 WDFY3 ORAI2 NDRG4 PIGO

5.21e-061985166603_DN
DrugThalidomide [50-35-1]; Up 200; 15.4uM; HL60; HG-U133A

EPHB2 MED18 ACACA SZT2 CCSER2 MPI

5.21e-061985161411_UP
DrugAC1L18AJ

ACACA PAM

4.90e-055512CID000000018
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A

EPHB2 MED18 SZT2 PLCG1 WDFY3

6.94e-051925154743_DN
DrugChlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; HL60; HT_HG-U133A

EPHB2 ACACA SZT2 KDM4C CCSER2

7.11e-051935151864_UP
DrugCP-690334-01 [459212-38-5]; Down 200; 10uM; PC3; HT_HG-U133A

EPHB2 KDM4C PAK6 DNAH7 FAM131B

7.11e-051935154558_DN
DrugClotrimazole [23593-75-1]; Down 200; 11.6uM; PC3; HT_HG-U133A

EPHB2 KDM4C SMPD1 PLCG1 PIGO

7.11e-051935155726_DN
Drugpaclitaxel; Down 200; 0.1uM; MCF7; HG-U133A

ADAM20 PAM PLCG1 ORAI2 PIGO

7.29e-05194515640_DN
DrugEthisterone [434-03-7]; Up 200; 12.8uM; PC3; HT_HG-U133A

ADGB PKNOX2 SZT2 KDM4C ADAM20

7.29e-051945153783_UP
Drug(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; PC3; HT_HG-U133A

EPHB2 KDM4C CCSER2 PLCG1 NDRG4

7.29e-051945154524_DN
DrugClindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; MCF7; HT_HG-U133A

LAMB1 PAM SMPD1 PIGO URGCP

7.47e-051955157172_DN
DrugProcyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A

EPHB2 MED18 TEX15 ORAI2 PIGO

7.47e-051955154817_UP
DrugPiretanide [55837-27-9]; Down 200; 11uM; MCF7; HT_HG-U133A

XYLT2 MED18 KDM4C LAMB1 NDRG4

7.65e-051965153567_DN
DrugMethotrexate [59-05-2]; Up 200; 8.8uM; PC3; HT_HG-U133A

EPHB2 KDM4C PLCG1 FAM131B MPI

7.65e-051965156318_UP
Drug3-Acetamidocoumarin [779-30-6]; Down 200; 19.6uM; HL60; HT_HG-U133A

EPHB2 XYLT2 KDM4C CCSER2 PIGO

7.65e-051965152941_DN
DrugPF-00539745-00 [351321-33-0]; Down 200; 10uM; MCF7; HT_HG-U133A

EPHB2 MED18 PCBP3 KDM4C PAK6

7.65e-051965155974_DN
DrugLiothyronine [6893-02-3]; Down 200; 6.2uM; PC3; HT_HG-U133A

EPHB2 SZT2 CCSER2 NDRG4 PIGO

7.65e-051965156602_DN
DrugNaloxone hydrochloride [357-08-4]; Down 200; 11uM; PC3; HT_HG-U133A

ACLY FGFR4 WDFY3 ORAI2 URGCP

7.65e-051965154645_DN
Drug1-phenylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A

EPHB2 PKNOX2 ACACA ADAM20 PLCG1

7.84e-0519751522_UP
DrugSulfanilamide [63-74-1]; Down 200; 23.2uM; PC3; HT_HG-U133A

EPHB2 FGFR4 TEX15 ORAI2 PIGO

7.84e-051975154474_DN
DrugRaloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; HL60; HT_HG-U133A

EPHB2 CCSER2 PLCG1 PTCH1 URGCP

7.84e-051975152738_DN
DrugSuccinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A

EPHB2 SZT2 FGFR4 PTCH1 MPI

7.84e-051975152821_UP
DrugSTOCK1N-35874; Down 200; 14uM; PC3; HT_HG-U133A

EPHB2 SZT2 CCSER2 PTCH1 ORAI2

7.84e-051975156583_DN
DrugGSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT_HG-U133A

MED18 SZT2 PLCG1 DNAH7 FAM131B

8.03e-051985157048_DN
DrugDipyridamole [58-32-2]; Up 200; 8uM; MCF7; HT_HG-U133A

EPHB2 PKNOX2 PCBP3 TEX15 DNAH7

8.03e-051985155617_UP
DrugAdamantamine fumarate [80789-67-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A

EPHB2 SZT2 LAMB1 PLCG1 MPI

8.22e-051995154806_DN
DrugOleandomycin phosphate [7060-74-4]; Down 200; 5uM; PC3; HT_HG-U133A

EPHB2 SMPD1 WDFY3 ORAI2 NDRG4

8.22e-051995154615_DN
DrugDiclofenac sodium [15307-79-6]; Down 200; 12.6uM; MCF7; HT_HG-U133A

MED18 KDM4C CCSER2 PLCG1 FGFR4

8.22e-051995157215_DN
Drug1,1-dimethylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A

EPHB2 PKNOX2 ACACA SMPD1 PLCG1

8.22e-0519951561_UP
Drug1,2-dithiol-3-thione

XYLT2 MAN2A1 ACLY AKR1D1 PAM AKR1A1 FGFR4 WDFY3 DYNC1I2

8.29e-05829519ctd:C049325
Drug2-phenylbenzothiazole

ACACA BSN

1.03e-047512CID000013439
Drugtrimethylamine-cyanoborane

ACACA ACLY

1.37e-048512CID006328234
DiseaseRhabdomyosarcoma

FGFR4 PTCH1

2.80e-0415492C0035412
Diseaselung squamous cell carcinoma (is_implicated_in)

FGFR4 PTCH1

7.28e-0424492DOID:3907 (is_implicated_in)
DiseaseDrugs used in diabetes use measurement

PAM FGFR4 PTCH1 DNAH7

8.51e-04255494EFO_0009924
Diseaseintestinal permeability measurement

PCBP3 KCNJ6

8.56e-0426492EFO_0011031
DiseaseCarcinoma, Basal Cell

ACTRT1 PTCH1

1.07e-0329492C4721806
Diseasedrug dependence

PKNOX2 NFASC

1.55e-0335492EFO_0003890

Protein segments in the cluster

PeptideGeneStartEntry
LAVPKHPYAAMENWG

TRHDE

396

Q9UKU6
WPEEHYAMVALNFVP

AHSA2P

241

Q719I0
YMSHRELPAWVSFPD

ESYT1

121

Q9BSJ8
HYWVGLDISPAMLDE

BUD23

76

O43709
GWLPEVISLHPGYMD

ADGB

271

Q8N7X0
LLMWRDHPEYPFHDE

AKR1D1

311

P51857
CWGTDYHLGMAIPDI

ADAM20

591

O43506
PFDMVYWTGDIPAHD

SMPD1

271

P17405
PELYGLMRECWHAAP

FGFR4

716

P22455
RHMFHVAWVDPEDPY

ACACA

1731

Q13085
FHMEEALDWPGVYLL

PAM

496

P19021
CPEPGHKGMDYRDWV

ORAI2

16

Q96SN7
ESPHERMHPYIELAW

ORAI2

136

Q96SN7
PLYDEVQMGPWDLHW

NPHS1

1191

O60500
VQMGPWDLHWPEDTY

NPHS1

1196

O60500
LLGDEHWATDPDMYL

PAK6

116

Q9NQU5
WAIDPFGHSPTMAYL

MAN2A1

286

Q16706
GLPRDHPESYHSFMW

GNPDA1

76

P46926
YIRGDMDHIEDPSWT

KCNJ6

116

P48051
YWPPLTHAAFIAMAG

BSN

2501

Q9UPA5
PHEPDGVALVWNMKY

DYNC1I2

306

Q13409
MVHPPSGWEEVSGYD

EPHB2

36

P29323
YWEDPDDMGHHLGPD

ENPP5

186

Q9UJA9
MDAGSLYEPVSPHWF

DDHD2

31

O94830
AHAAGVLMEPDDWPY

KDM4C

841

Q9H3R0
LCMDFYHDLPWRPAE

LAMB1

311

P07942
AEDKPYAELWMGTHP

MPI

41

P34949
DALAQAPMDGWPHSY

FAM131B

176

Q86XD5
MGEGDAFWAPSVLPH

PCBP3

1

P57721
APWHLRYLGQPEMGD

MED18

81

Q9BUE0
EWDHPEHPNGIMIGY

NFASC

951

O94856
YMWDEEGLEPIGNVH

CCSER2

511

Q9H7U1
PRHWEAMSAIVGYPL

DNAH7

851

Q8WXX0
DPGQMEAFLHLWPDG

HYAL3

371

O43820
WLFQHLMHPYPTEDE

PKNOX2

306

Q96KN3
ATAMLFDPAAWLHGP

SZT2

2851

Q5T011
LWEPMEHHGDPNIFY

NEXMIF

1341

Q5QGS0
PEWVHDKADYMPETR

PTCH1

946

Q13635
IHDWGLFAMEPIAAD

SETD1B

1836

Q9UPS6
MPECWDGEHDIETPY

NDRG4

1

Q9ULP0
EVIGHPVMPAYWALG

SI

1211

P14410
HPWDDISYVLPEHMS

ACLY

1086

P53396
WALHFLMDAQPGSEP

ACD

441

Q96AP0
HYPIERGLVTGWDDM

ACTRT1

71

Q8TDG2
LMHWPYAFERGDNPF

AKR1A1

111

P14550
LWHGAPPMAAVSLAY

URGCP

881

Q8TCY9
HPNWQFVDVYGMDPE

UCHL3

26

P15374
WHIMIPSDIEPDGSY

WDFY3

2171

Q8IZQ1
LDCWDGPDGMPVIYH

PLCG1

366

P19174
YPTMDSGEWDVLIAH

PIGO

216

Q8TEQ8
WAHNMGSEDYDCIPP

TEX15

126

Q9BXT5
ARGWAHIEPMYLPPD

TREX2

216

Q9BQ50
ASWLHAGPPHNEYME

XYLT2

761

Q9H1B5