Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranslation elongation factor activity

EIF5A EIF5A2 EIF5AL1

1.19e-0520453GO:0003746
GeneOntologyMolecularFunctionU6 snRNA binding

EIF5A EIF5AL1

7.43e-0418452GO:0017070
GeneOntologyMolecularFunctiontranslation factor activity, RNA binding

EIF5A EIF5A2 EIF5AL1

9.28e-0485453GO:0008135
GeneOntologyMolecularFunctionfatty acid ligase activity

ACSS2 ACSM1

1.56e-0326452GO:0015645
GeneOntologyMolecularFunctionCoA-ligase activity

ACSS2 ACSM1

1.68e-0327452GO:0016405
GeneOntologyMolecularFunctiontranslation regulator activity, nucleic acid binding

EIF5A EIF5A2 EIF5AL1

2.05e-03112453GO:0090079
GeneOntologyMolecularFunctionacid-thiol ligase activity

ACSS2 ACSM1

2.22e-0331452GO:0016878
GeneOntologyMolecularFunctionribosome binding

EIF5A EIF5A2 EIF5AL1

2.50e-03120453GO:0043022
GeneOntologyMolecularFunctionligase activity, forming carbon-sulfur bonds

ACSS2 ACSM1

3.85e-0341452GO:0016877
GeneOntologyBiologicalProcesspositive regulation of translational termination

EIF5A EIF5A2 EIF5AL1

3.88e-084453GO:0045905
GeneOntologyBiologicalProcesspositive regulation of translational elongation

EIF5A EIF5A2 EIF5AL1

9.67e-085453GO:0045901
GeneOntologyBiologicalProcessregulation of translational termination

EIF5A EIF5A2 EIF5AL1

8.08e-079453GO:0006449
GeneOntologyBiologicalProcesspositive regulation of protein-containing complex disassembly

EIF5A EIF5A2 EIF5AL1 SPAST

1.89e-0641454GO:0043243
GeneOntologyBiologicalProcessregulation of translational elongation

EIF5A EIF5A2 EIF5AL1

3.47e-0614453GO:0006448
GeneOntologyBiologicalProcesstranslational termination

EIF5A EIF5A2 EIF5AL1

6.46e-0617453GO:0006415
GeneOntologyBiologicalProcessregulation of protein-containing complex disassembly

EIF5A SPTBN5 EIF5A2 EIF5AL1 SPAST

1.51e-05144455GO:0043244
GeneOntologyBiologicalProcessprotein-containing complex disassembly

EIF5A SPTBN5 EIF5A2 EIF5AL1 KIF5B SPAST

3.84e-05291456GO:0032984
GeneOntologyBiologicalProcesscellular component disassembly

SREBF1 EIF5A SPTBN5 EIF5A2 EIF5AL1 ATG10 KIF5B SPAST

4.97e-05617458GO:0022411
GeneOntologyBiologicalProcesspositive regulation of muscle cell apoptotic process

EIF5A EIF5AL1 GRP

2.35e-0455453GO:0010661
GeneOntologyBiologicalProcesshematopoietic stem cell migration

GPLD1 BCL11B

3.03e-0412452GO:0035701
DomainIF5A_HYPUSINE

EIF5A EIF5A2 EIF5AL1

1.22e-083443PS00302
DomaineIF-5a

EIF5A EIF5A2 EIF5AL1

1.22e-083443PF01287
DomainTransl_elong_IF5A_C

EIF5A EIF5A2 EIF5AL1

1.22e-083443IPR020189
DomainTrans_elong_IF5A_hypusine_site

EIF5A EIF5A2 EIF5AL1

1.22e-083443IPR019769
DomainTransl_elong_IF5A

EIF5A EIF5A2 EIF5AL1

1.22e-083443IPR001884
DomaineIF-5a

EIF5A EIF5A2 EIF5AL1

1.22e-083443SM01376
DomainTranslation_prot_SH3-like

EIF5A EIF5A2 EIF5AL1

8.11e-0617443IPR008991
DomainRib_L2_dom2

EIF5A EIF5A2 EIF5AL1

9.71e-0618443IPR014722
Domain-

EIF5A EIF5A2 EIF5AL1

9.71e-06184432.30.30.30
DomainKOW

EIF5A EIF5A2

2.94e-0411442IPR005824
DomainKOW

EIF5A EIF5A2

2.94e-0411442PF00467
DomainAMP-bd_C

ACSS2 ACSM1

7.21e-0417442IPR025110
DomainAMP-binding_C

ACSS2 ACSM1

7.21e-0417442PF13193
DomainNA-bd_OB-fold

EIF5A EIF5A2 EIF5AL1

9.83e-0483443IPR012340
DomainAMP-binding_CS

ACSS2 ACSM1

1.70e-0326442IPR020845
DomainAMP_BINDING

ACSS2 ACSM1

1.97e-0328442PS00455
DomainAMP-binding

ACSS2 ACSM1

2.26e-0330442PF00501
DomainAMP-dep_Synth/Lig

ACSS2 ACSM1

2.26e-0330442IPR000873
DomainZINC_FINGER_C2H2_2

ZNF521 SALL4 BCL11B TRMT1L ZNF423 ZNF445

9.21e-03775446PS50157
DomainZINC_FINGER_C2H2_1

ZNF521 SALL4 BCL11B TRMT1L ZNF423 ZNF445

9.32e-03777446PS00028
DomainZnf_C2H2-like

ZNF521 SALL4 BCL11B TRMT1L ZNF423 ZNF445

1.04e-02796446IPR015880
DomainZnf_C2H2

ZNF521 SALL4 BCL11B TRMT1L ZNF423 ZNF445

1.10e-02805446IPR007087
DomainZnF_C2H2

ZNF521 SALL4 BCL11B TRMT1L ZNF423 ZNF445

1.12e-02808446SM00355
PathwayREACTOME_HYPUSINE_SYNTHESIS_FROM_EIF5A_LYSINE

EIF5A EIF5A2 EIF5AL1

2.27e-075413MM14823
Pubmed

Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression.

EIF5A EIF5A2 EIF5AL1

2.31e-09347311161802
Pubmed

New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape.

EIF5A EIF5A2 EIF5AL1

2.31e-09347336848144
Pubmed

Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells.

EIF5A EIF5A2 EIF5AL1

2.31e-09347316519677
Pubmed

Biological Relevance and Therapeutic Potential of the Hypusine Modification System.

EIF5A EIF5A2 EIF5AL1

2.31e-08547326037925
Pubmed

Progenitor cell diversity in the developing mouse neocortex.

MKI67 BCL11B GRP

6.55e-071347333649223
Pubmed

Comparison of Human Eukaryotic Translation Initiation Factors 5A1 and 5AL1: Identification of Amino Acid Residues Important for EIF5A1 Lysine 50 Hypusination and Its Protein Stability.

EIF5A EIF5AL1

1.79e-06247237047039
Pubmed

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.

EIF5A EIF5AL1

1.79e-06247231130465
Pubmed

Independent roles of eIF5A and polyamines in cell proliferation.

EIF5A EIF5AL1

1.79e-06247215377278
Pubmed

Sequence determination and cDNA cloning of eukaryotic initiation factor 4D, the hypusine-containing protein.

EIF5A EIF5AL1

1.79e-0624722492279
Pubmed

The N-terminal region of eukaryotic translation initiation factor 5A signals to nuclear localization of the protein.

EIF5A EIF5AL1

1.79e-06247217707773
Pubmed

Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A.

EIF5A EIF5AL1

1.79e-06247212894223
Pubmed

Targeted inhibition of eIF5Ahpu suppresses tumor growth and polarization of M2-like tumor-associated macrophages in oral cancer.

EIF5A EIF5AL1

1.79e-06247237653021
Pubmed

Identification of a new member of the human eIF-5A gene family.

EIF5A EIF5AL1

1.79e-0624727622067
Pubmed

Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation.

EIF5A EIF5AL1

1.79e-0624728253832
Pubmed

Eukaryotic initiation factor 4D. Purification from human red blood cells and the sequence of amino acids around its single hypusine residue.

EIF5A EIF5AL1

1.79e-0624723095320
Pubmed

Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger protein.

ZNF521 ZNF423

1.79e-06247212393497
Pubmed

Exosomal EIF5A derived from Lewis lung carcinoma induced adipocyte wasting in cancer cachexia.

EIF5A EIF5AL1

1.79e-06247237743008
Pubmed

Homology modelling of the human eukaryotic initiation factor 5A (eIF-5A).

EIF5A EIF5AL1

1.79e-06247211742107
Pubmed

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.

EIF5A EIF5AL1

1.79e-06247220501948
Pubmed

Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis.

EIF5A EIF5AL1

5.36e-06347237333770
Pubmed

Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status.

SREBF1 ACSS2

5.36e-06347211739104
Pubmed

Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.

EIF5A EIF5AL1

5.36e-06347236893894
Pubmed

Direct transcriptional repression of Zfp423 by Zfp521 mediates a bone morphogenic protein-dependent osteoblast versus adipocyte lineage commitment switch.

ZNF521 ZNF423

5.36e-06347224891617
Pubmed

ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies.

ZNF521 ZNF423

5.36e-06347226788497
Pubmed

Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

EIF5A EIF5AL1

5.36e-06347221850436
Pubmed

Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.

EIF5A EIF5AL1

5.36e-06347232817651
Pubmed

Identification and characterization of eukaryotic initiation factor 5A-2.

EIF5A EIF5A2

5.36e-06347214622290
Pubmed

The role of polyamines in supporting growth of mammalian cells is mediated through their requirement for translation initiation and elongation.

EIF5A EIF5AL1

5.36e-06347220181941
Pubmed

Evidences of a role for eukaryotic translation initiation factor 5A (eIF5A) in mouse embryogenesis and cell differentiation.

EIF5A EIF5AL1

5.36e-06347220458750
Pubmed

Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging.

EIF5A EIF5AL1

5.36e-06347212210765
Pubmed

A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis.

MKI67 CARS1 BCL11B

5.88e-062647326651292
Pubmed

Robo1 modulates proliferation and neurogenesis in the developing neocortex.

MKI67 BCL11B ZNF423

6.61e-062747324741061
Pubmed

Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.

MKI67 ZNF521 BCL11B

8.25e-062947331491374
Pubmed

Proteomic dissection of the von Hippel-Lindau (VHL) interactome.

EIF5A COL4A3 EIF5A2 RPS3A

9.63e-069847421942715
Pubmed

Haploinsufficiency of MeCP2-interacting transcriptional co-repressor SIN3A causes mild intellectual disability by affecting the development of cortical integrity.

MKI67 BCL11B

1.07e-05447227399968
Pubmed

BCL11B expression in intramembranous osteogenesis during murine craniofacial suture development.

MKI67 BCL11B

1.07e-05447225511173
Pubmed

The genomic structure encoding human initiation factor eIF-5A.

EIF5A EIF5AL1

1.07e-0544727545941
Pubmed

The eukaryotic cofactor for the human immunodeficiency virus type 1 (HIV-1) rev protein, eIF-5A, maps to chromosome 17p12-p13: three eIF-5A pseudogenes map to 10q23.3, 17q25, and 19q13.2.

EIF5A EIF5AL1

1.07e-0544727759117
Pubmed

Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.

EIF5A EIF5A2

1.07e-05447222927971
Pubmed

DHPS-dependent hypusination of eIF5A1/2 is necessary for TGFβ/fibronectin-induced breast cancer metastasis and associates with prognostically unfavorable genomic alterations in TP53.

EIF5A EIF5A2

1.07e-05447231558321
Pubmed

The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).

EIF5A EIF5A2

1.07e-05447216452303
Pubmed

GTF2I dosage regulates neuronal differentiation and social behavior in 7q11.23 neurodevelopmental disorders.

MKI67 BCL11B

1.07e-05447238019906
Pubmed

Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1.

MKI67 BCL11B

1.78e-05547228507510
Pubmed

Neuron-specific ablation of eIF5A or deoxyhypusine synthase leads to impairments in growth, viability, neurodevelopment, and cognitive functions in mice.

EIF5A EIF5AL1

1.78e-05547234688659
Pubmed

Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cells.

ZNF521 ZNF423

1.78e-05547214630787
Pubmed

Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood.

MKI67 BCL11B

2.67e-05647217631058
Pubmed

Identification of Evi-3, a novel common site of retroviral integration in mouse AKXD B-cell lymphomas.

ZNF521 KIF5B

2.67e-0564728107195
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

MKI67 SART1 BTAF1 RGS3 SBSN

3.31e-0527247531010829
Pubmed

PAK1 regulates cortical development via promoting neuronal migration and progenitor cell proliferation.

MKI67 BCL11B

3.74e-05747226043730
Pubmed

S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration.

MKI67 BCL11B

3.74e-05747223359715
Pubmed

Expression pattern of Nav2 in the murine CNS with development.

MKI67 BCL11B

3.74e-05747232081718
Pubmed

EphA4 Regulates the Balance between Self-Renewal and Differentiation of Radial Glial Cells and Intermediate Neuronal Precursors in Cooperation with FGF Signaling.

MKI67 BCL11B

3.74e-05747225978062
Pubmed

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing.

KIF5B SPAST

4.98e-05847220530212
Pubmed

YAP maintains the production of intermediate progenitor cells and upper-layer projection neurons in the mouse cerebral cortex.

MKI67 BCL11B

4.98e-05847234931379
Pubmed

Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling.

MKI67 BCL11B

4.98e-05847223015591
Pubmed

Upregulation of MicroRNA miR-9 Is Associated with Microcephaly and Zika Virus Infection in Mice.

MKI67 BCL11B

4.98e-05847230264295
Pubmed

Disruption of NEUROD2 causes a neurodevelopmental syndrome with autistic features via cell-autonomous defects in forebrain glutamatergic neurons.

MKI67 BCL11B

4.98e-05847234188164
Pubmed

Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m3C modification.

MKI67 BCL11B

6.40e-05947236764294
Pubmed

The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a.

MKI67 BCL11B

6.40e-05947225972180
Pubmed

TBL1XR1 Ensures Balanced Neural Development Through NCOR Complex-Mediated Regulation of the MAPK Pathway.

MKI67 BCL11B

6.40e-05947233708771
Pubmed

The Metabolite Saccharopine Impairs Neuronal Development by Inhibiting the Neurotrophic Function of Glucose-6-Phosphate Isomerase.

MKI67 BCL11B

6.40e-05947235135854
Pubmed

The basic helix-loop-helix transcription factor TCF4 impacts brain architecture as well as neuronal morphology and differentiation.

MKI67 BCL11B

6.40e-05947231919899
Pubmed

DISC1-dependent switch from progenitor proliferation to migration in the developing cortex.

MKI67 BCL11B

6.40e-05947221471969
Pubmed

Gatad2b, associated with the neurodevelopmental syndrome GAND, plays a critical role in neurodevelopment and cortical patterning.

MKI67 BCL11B

6.40e-05947238238293
Pubmed

Essential role of PDZ-RGS3 in the maintenance of neural progenitor cells.

MKI67 RGS3

6.40e-05947220629178
Pubmed

ATRX is required for maintenance of the neuroprogenitor cell pool in the embryonic mouse brain.

MKI67 BCL11B

6.40e-05947225395668
Pubmed

Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis.

MKI67 BCL11B

6.40e-05947225533347
Pubmed

KIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development.

MKI67 RGS3

6.40e-05947230006548
Pubmed

LIMK1 and LIMK2 regulate cortical development through affecting neural progenitor cell proliferation and migration.

MKI67 BCL11B

6.40e-05947231319858
Pubmed

Tcf4 is required for correct brain development during embryogenesis.

MKI67 BCL11B

6.40e-05947232474139
Pubmed

Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome.

MKI67 BCL11B

6.40e-05947231541646
Pubmed

Spatial transcriptome reveals the region-specific genes and pathways regulated by Satb2 in neocortical development.

MKI67 BCL11B

7.99e-051047239095712
Pubmed

Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes.

EIF5A EIF5AL1

7.99e-051047210944119
Pubmed

Reelin sets the pace of neocortical neurogenesis.

MKI67 BCL11B

7.99e-051047222069190
Pubmed

The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex.

MKI67 BCL11B

7.99e-051047225934499
Pubmed

Mutations in SMARCB1 and in other Coffin-Siris syndrome genes lead to various brain midline defects.

MKI67 BCL11B

7.99e-051047231273213
Pubmed

Enhanced Abventricular Proliferation Compensates Cell Death in the Embryonic Cerebral Cortex.

MKI67 BCL11B

7.99e-051047227620979
Pubmed

Normal radial migration and lamination are maintained in dyslexia-susceptibility candidate gene homolog Kiaa0319 knockout mice.

MKI67 BCL11B

7.99e-051047227510895
Pubmed

ATF5 deficiency causes abnormal cortical development.

MKI67 BCL11B

7.99e-051047233790322
Pubmed

The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain.

SREBF1 BCL11B

7.99e-051047230074985
Pubmed

KCTD10 regulates brain development by destabilizing brain disorder-associated protein KCTD13.

MKI67 BCL11B

7.99e-051047238489388
Pubmed

FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry.

MKI67 BCL11B

7.99e-051047225402856
Pubmed

Glycine receptors control the generation of projection neurons in the developing cerebral cortex.

MKI67 BCL11B

7.99e-051047224926615
Pubmed

Notch Activation by Shootin1 Opposing Activities on 2 Ubiquitin Ligases.

MKI67 BCL11B

9.75e-051147228981589
Pubmed

The cerebrospinal fluid provides a proliferative niche for neural progenitor cells.

MKI67 BCL11B

9.75e-051147221382550
Pubmed

Gli3 is required for maintenance and fate specification of cortical progenitors.

MKI67 BCL11B

9.75e-051147221525285
Pubmed

A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion.

MKI67 BCL11B

9.75e-051147234587386
Pubmed

Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers.

MKI67 HEYL

9.75e-051147221989910
Pubmed

7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome.

MKI67 BCL11B

9.75e-051147236111785
Pubmed

Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes.

MKI67 BCL11B

9.75e-051147232115408
Pubmed

Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex.

MKI67 BCL11B

9.75e-051147231794381
Pubmed

The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development.

MKI67 BCL11B

9.75e-051147231816041
Pubmed

FASN-dependent de novo lipogenesis is required for brain development.

MKI67 BCL11B

9.75e-051147234996870
Pubmed

Differential requirements of tubulin genes in mammalian forebrain development.

MKI67 BCL11B

9.75e-051147231386652
Pubmed

A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation.

MKI67 BCL11B

9.75e-051147234614421
Pubmed

Oxidative stress regulates progenitor behavior and cortical neurogenesis.

MKI67 BCL11B

9.75e-051147232041791
Pubmed

Regulation of neural stem cell differentiation and brain development by MGAT5-mediated N-glycosylation.

MKI67 BCL11B

9.75e-051147237172586
Pubmed

Dual effect of CTCF loss on neuroprogenitor differentiation and survival.

MKI67 BCL11B

1.17e-041247224553927
Pubmed

Ulk4 Regulates Neural Stem Cell Pool.

MKI67 BCL11B

1.17e-041247227300315
Pubmed

The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium.

MKI67 KIF5B

1.17e-041247215834408
Cytoband5q14.1

ATG10 BHMT

7.42e-04394725q14.1
GeneFamilyAcyl-CoA synthetase family

ACSS2 ACSM1

7.35e-042628240
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF521 SALL4 BCL11B ZNF423 ZNF445

4.48e-0371828528
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MKI67 BCL11B ZP2 GRP

1.89e-051504742ba55e51877e2e749cccdae7df5d885dc55b2587
ToppCellHealthy_donor-CD8+_T_naive|Healthy_donor / disease group, cell group and cell class (v2)

CARS1 BCL11B DSEL RPS3A

3.02e-0516947466216758e581365f10c2a66714d83a606ad23af0
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

ZNF521 SASH1 ZNF423 TLL1

3.54e-0517647498c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

ZNF521 SASH1 ZNF423 TLL1

3.54e-05176474c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellCOVID-19_Convalescent-Lymphoid_T/NK-CD8+_T_naive|COVID-19_Convalescent / Disease group, lineage and cell class

CARS1 BCL11B DSEL RPS3A

4.21e-051844740299cd30a3ea8e861a9d529043c204048ae21d29
ToppCellremission-CD8+_T_naive|remission / disease stage, cell group and cell class

CARS1 BCL11B DSEL RPS3A

4.21e-05184474fe20fa4457d4a4a75689978275b0afb5f6243faf
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

CARS1 BCL11B DSEL RPS3A

4.30e-05185474863a3d44c1f115942d7a2a2b63a92fe5fc768814
ToppCellremission-CD8+_T_naive|World / disease stage, cell group and cell class

CARS1 BCL11B DSEL RPS3A

4.30e-0518547469304d7dd406ac7e96d51c239d7035a06d88704f
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CARS1 BCL11B DSEL RPS3A

4.30e-0518547427dbfcd40ec832d5cf757331d8af3b5176ae90fb
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ZNF521 SASH1 ZNF423 TLL1

4.30e-051854744a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

ZNF521 SASH1 ZNF423 TLL1

4.30e-05185474f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellCOVID-19_Convalescent-CD8+_T_naive|COVID-19_Convalescent / Disease condition and Cell class

CARS1 BCL11B DSEL RPS3A

4.30e-051854742f8277a0b58fb0c49fa76ff6dfa6da961da1f9f5
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ZNF521 SASH1 ZNF423 TLL1

4.30e-0518547436ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CARS1 BCL11B DSEL RPS3A

4.30e-051854741c23891e4d75f99296d1304af7a9d6c3cb28d04c
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CARS1 BCL11B DSEL RPS3A

4.30e-05185474ca8e921a6b45cd39474b9f86c95e7be023585c5d
ToppCellControl-Lymphocyte-T_NK-CD8_Naive|Control / Disease, Lineage and Cell Type

CARS1 BCL11B DSEL RPS3A

4.48e-05187474cf8bebef36e1ec76a22f229e5c073b3a201d1b93
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN5 ZNF521 SASH1 TLL1

4.48e-0518747435c382c0aabd46906113e5db30ea24bb8e658899
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

ZNF521 SASH1 ZNF423 TLL1

4.48e-051874742d20193a6cacdfa4877457c97b0077408942186c
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A3 HEYL ZNF423 IGDCC4

4.48e-05187474ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCellmild_COVID-19-CD8+_T_naive|mild_COVID-19 / disease group, cell group and cell class (v2)

CARS1 BCL11B DSEL RPS3A

4.58e-0518847460d27014e5f9e562efe2a602482ea1d07efd0331
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

ZNF521 SASH1 ZNF423 TLL1

4.58e-05188474d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellmild_COVID-19-CD8+_T_naive|World / disease group, cell group and cell class (v2)

CARS1 BCL11B DSEL RPS3A

4.58e-05188474ddfb1c64305825fb0bc23819aa001bfc2ac4c2b2
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZNF521 NCOA7 SASH1 TLL1

4.67e-05189474c121817ddad164e9cfe382c43d0cbc9215508d02
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZNF521 SASH1 ZNF423 TLL1

4.77e-051904741caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A3 NCOA7 SASH1 ACSM1

4.77e-0519047412992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZNF521 NCOA7 SASH1 TLL1

4.87e-051914742f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL4A3 NCOA7 SASH1 ACSM1

4.87e-05191474d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A3 NCOA7 SASH1 ACSM1

4.87e-0519147470c067c54084bfb02c29bab085f4defd477194fb
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CARS1 BCL11B DSEL RPS3A

4.97e-05192474ad2e0f35d50fe4e6977eba8a7a2bd990f6946305
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZNF521 SASH1 ZNF423 TLL1

4.97e-05192474c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CARS1 BCL11B DSEL RPS3A

4.97e-05192474284955fec5103194d416320f41fa4d87c7efc4fb
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CARS1 BCL11B DSEL RPS3A

4.97e-051924740d3b2b9cd586a4adbc3755563dd50b140227c287
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CARS1 BCL11B DSEL RPS3A

4.97e-0519247467f50e5b1d449923002dc5b5d0c4d32c523034d3
ToppCellControl-CD8+_T_naive|Control / Disease condition and Cell class

SREBF1 CARS1 BCL11B DSEL

5.07e-05193474627d345baf1940218c61907305705298e473dbab
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

COL4A3 NCOA7 SASH1 ACSM1

5.07e-05193474dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-CD8_Naive|Multiple_Sclerosis / Disease, Lineage and Cell Type

CARS1 BCL11B DSEL RPS3A

5.17e-0519447442a9a170022f07445a7ee2577707924bbc0269db
ToppCellIPF-Endothelial|IPF / Disease state, Lineage and Cell class

ZNF521 SASH1 ZNF423 TLL1

5.17e-051944749591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCellAdult-Endothelial|Adult / Lineage, Cell type, age group and donor

ZNF521 SASH1 ZNF423 TLL1

5.17e-05194474963b3fbee0575af8379baa397ace65949eaf34f7
ToppCellIPF-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

ZNF521 SASH1 ZNF423 TLL1

5.27e-05195474120296531bbc8080dcabacbd64733cc1dc34603a
ToppCellIPF-Endothelial-VE_Peribronchial|IPF / Disease state, Lineage and Cell class

ZNF521 SASH1 ZNF423 TLL1

5.27e-051954742c3ad3cb79f11119ac69c413a938d21199145040
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF521 SASH1 ZNF423 TLL1

5.27e-05195474094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF521 SASH1 ZNF423 TLL1

5.49e-051974740f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCellnucseq-Endothelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZNF521 SASH1 ZNF423 TLL1

5.49e-05197474ebf9be068eaa658493fa7884fd19f34642922acb
ToppCell(221)_CD8+_Naive_T_cell|World / immune cells in Peripheral Blood (logTPM normalization)

CARS1 BCL11B DSEL RPS3A

5.49e-0519747459621a1f016b9f467e69bd5977ccdafa03b4ce21
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MKI67 EIF5A EIF5AL1 SBSN

5.49e-051974742430f31d9312338e0ca23bfc6bdb0365340860fd
ToppCellIIF-Lymphocyte-T_NK-CD8_Naive|IIF / Disease, Lineage and Cell Type

CARS1 BCL11B DSEL RPS3A

5.49e-05197474fa376bde80ed0ae57ae064ff7165cfb870724b93
ToppCellmild|World / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

EIF5A MLLT6 BCL11B RPS3A

5.60e-051984743cef2e13d5ec71bb265171239980697a2560fa30
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T8_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CARS1 EIF5AL1 BCL11B DSEL

5.71e-0519947440eb207fa0f07e2e4d0be69530b8f61f7ea49c73
ToppCellParenchymal-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF521 SASH1 ZNF423 TLL1

5.71e-05199474a4a9a1c2a34b5a8318a55d1211d6c8661ca9793e
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T8_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CARS1 EIF5AL1 BCL11B DSEL

5.71e-0519947467b9ff07de5be0895612c201cb21e66a3f88669a
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T8_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CARS1 EIF5AL1 BCL11B DSEL

5.71e-05199474e47f8314a4822bf00d0999316457f95c338585e1
ToppCellcontrol-CD8+_T_naive|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CARS1 BCL11B DSEL RPS3A

5.71e-051994746a61ce7404c65e506091fee99a2001f5a9b39f31
ToppCellsevere-CD8+_T_naive|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CARS1 BCL11B DSEL RPS3A

5.71e-05199474656e639228b3f2dca6955a487e4999e73a69bc51
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T8_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CARS1 EIF5AL1 BCL11B DSEL

5.71e-051994746ed413872301707dc73ae66365bee94cd38a292c
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-CD8+_T_naive|Multiple_Sclerosis / Disease, condition lineage and cell class

CARS1 BCL11B DSEL RPS3A

5.82e-052004743c919578aed30f77408a3405bce7b71bcda203e0
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD8+_T_naive|COVID-19_Mild / Disease, condition lineage and cell class

CARS1 BCL11B DSEL RPS3A

5.82e-052004747192138e2704c030d70561bcd59259fb3ad82f06
ToppCellMS-IIF-Lymphocyte-T/NK-CD8+_T_naive|IIF / Disease, condition lineage and cell class

CARS1 BCL11B DSEL RPS3A

5.82e-05200474350b189d0baca9516375786c3712c76c6b4fb390
ToppCellmild-CD8+_T_naive|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CARS1 BCL11B DSEL RPS3A

5.82e-05200474c2513047ef110a64c89a624e299cb9600a9cb92c
ToppCellCOVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-CD8+_T_naive|COVID-19_Convalescent / Disease, condition lineage and cell class

CARS1 BCL11B DSEL RPS3A

5.82e-0520047465ae349fac4084faacbc6a645a92398f6324770e
ToppCellCOVID-19_Mild-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

MIGA1 PLCH1 SASH1

3.03e-041244735ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MKI67 SALL4 PLCH1

3.18e-0412647369b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MKI67 SALL4 PLCH1

3.18e-041264736cb89754010d64875e115da6c5805efac7a4a82d
ToppCellCerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Cerebellum / BrainAtlas - Mouse McCarroll V32

BCL11B PAK6 GRP

3.48e-04130473ab141d91988a5de6d092757377a53f7de3707556
ToppCellCerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Cerebellum / BrainAtlas - Mouse McCarroll V32

BCL11B PAK6 GRP

3.48e-041304733d81151ee1369d819843826fc6ac197d83255e1d
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-6|TCGA-Thryoid / Sample_Type by Project: Shred V9

DLGAP1 ATG10 IGDCC4

3.64e-04132473b7611c6a5c86908132e7ab3e41d67277e8142db1
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Follicular-6|TCGA-Thryoid / Sample_Type by Project: Shred V9

ATG10 PRM3 IGDCC4

3.89e-041354738197d49e697a1fdcd64040ea7a7f0b3ad0a756eb
ToppCell10x5'-blood-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|blood / Manually curated celltypes from each tissue

RGS3 IGDCC4 ACSM1

3.97e-04136473f024015bf60e64b8657e410e24995a1edec85196
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPLD1 BCL11B ACSS2

4.15e-0413847319ffd66256fa94d728138d37d0a5a3bac7722dbb
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPLD1 BCL11B ACSS2

4.15e-04138473321070b6900887b27da0f2b25808a05a8ab89ee7
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MKI67 BCL11B GRP

4.24e-04139473ecc2a6ecc27748c50885cd4f0ad8a8cd1252aee6
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

EIF5A2 SPAST DSEL

4.33e-041404730e1e9281de87df178ac41ed6b697b4fa09be2749
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CARS1 BCL11B RPS3A

4.70e-04144473ea174487f8ade90deb33b964a7f7e65062606565
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEYL ZP2 ACSM1

4.70e-041444731d05aa08603cba28c0c6511767e434c1f592a3aa
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEYL ZP2 ACSM1

4.70e-04144473d3f6f5da56794367ee3776bfd3a9dcf893efe0f0
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Cpne7|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BCL11B ZP2 GRP

5.19e-041494738638b3819193d11411df58964069fec583f617f4
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF521 RGS3 TLL1

5.29e-041504734f31867cb85253ff6d22f3b02ef972a42cb41123
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8|TCGA-Bladder / Sample_Type by Project: Shred V9

GPLD1 SRRM5 BHMT

5.29e-041504731aa9320d97ff10994ea024751790524fe133aba9
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BCL11B ZP2 GRP

5.50e-04152473b6a7453fbf9f898e4f222b215907c9a110baa2f6
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CARS1 SART1 TRMT1L

5.60e-04153473553dff9688a1996d8f4ba16e60c683593d781389
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CARS1 SART1 TRMT1L

5.60e-0415347388ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPLD1 ACSS2 BHMT

5.71e-04154473a5289000597068ee8d559f89bce7bce31f35dd57
ToppCellnormal-na-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

EIF5AL1 BCL11B DSEL

5.82e-0415547308295584395e8d9cfc1b1648f98754b3ac53e587
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 EIF5AL1 PAK6

5.82e-04155473969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTBN5 BCL11B GRP

5.93e-04156473fe383ce3a0c37f7343d7026cb51260a04d4c2829
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RGS3 ZNF423 TLL1

6.04e-04157473275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCellControl-Endothelial-Epi-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCOA7 HEYL SALL4

6.04e-041574734d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCellControl-Endothelial-Epi-like-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCOA7 HEYL SALL4

6.04e-041574732c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCellHealthy/Control-CD8+_T_naive|Healthy/Control / Disease group and Cell class

BCL11B DSEL RPS3A

6.38e-04160473e1386c21fcbbf57fa32d8bdfba3cb1887477ff73
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EIF5A2 TLL1 IGDCC4

6.38e-04160473778faada072e3abfa76a9a06fd4885fb63de7902
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D122|Adult / Lineage, Cell type, age group and donor

ZNF423 TLL1 BHMT

6.38e-041604730cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 NCOA7 PLCH1

6.50e-041614731f4614ae15bd2fc08e555cea4d0152c4a940d048
ToppCell343B-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

NCOA7 SRRM5 RPS3A

6.50e-04161473537a1d86de99a493b0345ca0f760994260e97049
ToppCellHealthy_donor-CD8+_T_naive|World / disease group, cell group and cell class (v2)

CARS1 BCL11B DSEL

6.50e-041614738a61395af33132783a0a37956c6f821aba5d3b1e
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTBN5 BCL11B GRP

6.61e-0416247358da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTBN5 BCL11B GRP

6.61e-041624734d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_RSAD2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BCL11B ZP2 TLL1

6.85e-041644731ddfa222732ecfa0fbc359fb342a9fed8bd86272
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SREBF1 ACSS2 BHMT

6.85e-0416447390afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCellnucseq-Immune-Hematopoietic-Granulocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

INTS6L ZNF521 BMP2K

6.98e-0416547337615622c736e43260c38016e7c9e565ac97a3e8
ToppCellnucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

INTS6L ZNF521 BMP2K

6.98e-04165473640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCellnucseq-Immune-Hematopoietic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

INTS6L ZNF521 BMP2K

6.98e-04165473f3df74b5763130c71c0a482a3a23f6b22acc2892
DiseaseSelf-injurious behavior

SPTBN5 NCOA7 ATG10

2.18e-0478443HP_0100716
Diseasekidney disease (biomarker_via_orthology)

MKI67 SREBF1

4.48e-0421442DOID:557 (biomarker_via_orthology)
Diseaseselenium measurement

ZNF521 BHMT

8.60e-0429442EFO_0006331
DiseaseQT interval

EIF5A NCOA7 EIF5AL1 MIGA1 BTBD10

1.16e-03534445EFO_0004682
Diseasehereditary spastic paraplegia (implicated_via_orthology)

KIF5B SPAST

1.89e-0343442DOID:2476 (implicated_via_orthology)
Diseasereading and spelling ability

NEB SASH1 ZNF423

1.96e-03166443EFO_0005301
Diseasecalcium measurement

SREBF1 CARS1 MIGA1 BCL11B BTBD10

2.35e-03628445EFO_0004838
DiseaseIGFBP-3 measurement

DLGAP1 PAK6

2.96e-0354442EFO_0004626

Protein segments in the cluster

PeptideGeneStartEntry
EKHGSWGSGLDMHTK

BHMT

326

Q93088
KGGVDHTKMSLHGAS

BTBD10

41

Q9BSF8
FSKMKTSRHSSGGGG

MLLT6

181

P55198
HVTGSGASAGTHKRM

MLLT6

431

P55198
SHVIGIKGDKGSMGH

COL4A3

1261

Q01955
MKGLSGSRSHHHGVT

DLGAP1

1

O14490
KNGSVMSHLGASTHG

ATG10

51

Q9H0Y0
KHLGRAELGMGDSTS

ACSS2

251

Q9NR19
KQDMSKSNGKRHHGT

BMP2K

986

Q9NSY1
MGGGVSEGRSHSKRK

IGDCC4

1046

Q8TDY8
TLKKELGRNGGSMHH

RGS3

981

P49796
IKVKNHSGGGMSLTH

INTS6L

451

Q5JSJ4
QTSSGKTHTMEGKLH

KIF5B

86

P33176
GTNRHGMKAAKHGSE

PAK6

211

Q9NQU5
VEMSTSKTGKHGHAK

EIF5A2

41

Q9GZV4
VGHLMGKKSTGESSS

GRP

46

P07492
TVDHLKMLHATGGTG

HEYL

91

Q9NQ87
VEMSTSKTGKHGHAK

EIF5A

41

P63241
HTHTEPTGDGKSMKA

MKI67

1661

P46013
KGRHKAFGTCSSHLM

OR2B11

236

Q5JQS5
VEMSASKTGKHGHAK

EIF5AL1

41

Q6IS14
SSKLTRHMKTHGQIG

BCL11B

836

Q9C0K0
KGSTSEKDGMHHTVT

BTAF1

951

O14981
KQDMSKSNGKRHHGT

BMP2KL

236

Q5H9B9
GAGADTLKTLGSHMS

SALL4

251

Q9UJQ4
GLSNMGSHTGKELDK

SBSN

71

Q6UWP8
AEGSKKSLSSEGHHM

DSEL

836

Q8IZU8
STGHGRGHESSMKKL

PRM3

21

Q9NNZ6
SSHGHVMSTGLLEAK

MIGA1

616

Q8NAN2
GHVRRHMNKGETKSS

TRMT1L

201

Q7Z2T5
HTGHLTIAGCKMSKS

CARS1

396

P49589
HTTGGLGDHAMSKKR

TLL1

91

O43897
ELSSQTGGGMHKKDT

NCOA7

421

Q8NI08
GKLMELHGEGSSSGK

RPS3A

226

P61247
TVMKTGSAGLSGHHR

SPAST

251

Q9UBP0
KTALMKGEDGGHSLS

SPTBN5

3231

Q9NRC6
TMGKHTGGHLTATNL

SREBF1

681

P36956
TSGTTGFPKMAKHSH

ACSM1

226

Q08AH1
MGRHSQSRSHSKGKS

SRRM5

326

B3KS81
KIHGTFHMQKTGNGS

ZNF521

1036

Q96K83
DKAMGKLGTSLSSGH

GPLD1

641

P80108
GEMKKGLGSLSHGRT

SASH1

391

O94885
HRFHGKGSGKMKTER

SART1

731

O43290
KKSHGRSLMTNFGKH

PLCH1

541

Q4KWH8
ESLKHGCGKHFRMSS

ZNF445

411

P59923
KIHGTFHMQKLAGSS

ZNF423

1036

Q2M1K9
GSRGAMDTKGHKTAG

ZP2

696

Q05996
RAKHRKEGSHGLSML

NEB

5761

P20929