Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	axonogenesis	ARHGAP32 PLXNB2 ADARB1 PTK7 BRAF AFG3L2 SEMA3B TRIM46 HSPG2 CHODL LAMA2 LAMA5 LAMB2 LAMB3 VANGL2 SPTBN4 SIPA1L1 BARHL2	4.94e-06	566	189	18	GO:0007409
GeneOntologyBiologicalProcess	axon development	ARHGAP32 EPB41L3 PLXNB2 ADARB1 PTK7 BRAF AFG3L2 SEMA3B TRIM46 HSPG2 CHODL LAMA2 LAMA5 LAMB2 LAMB3 VANGL2 SPTBN4 SIPA1L1 BARHL2	7.47e-06	642	189	19	GO:0061564
GeneOntologyCellularComponent	laminin complex	LAMA5 LAMB2 LAMB3	9.14e-05	10	195	3	GO:0043256
GeneOntologyCellularComponent	laminin-11 complex	LAMA5 LAMB2	2.58e-04	3	195	2	GO:0043260
GeneOntologyCellularComponent	extracellular matrix	IMPG1 LRRC24 LINGO3 PLXNB2 SEMA3B GPC1 HSPG2 COL7A1 LAMA2 LAMA5 LAMB2 LAMB3 LGALS4 SNED1 ANGPTL6 PLXDC2	4.53e-04	656	195	16	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	IMPG1 LRRC24 LINGO3 PLXNB2 SEMA3B GPC1 HSPG2 COL7A1 LAMA2 LAMA5 LAMB2 LAMB3 LGALS4 SNED1 ANGPTL6 PLXDC2	4.69e-04	658	195	16	GO:0030312
GeneOntologyCellularComponent	laminin-5 complex	LAMA5 LAMB3	5.13e-04	4	195	2	GO:0005610
GeneOntologyCellularComponent	neuromuscular junction	SYNC DLG3 LAMA2 LAMA5 LAMB2 GRIA1	6.43e-04	112	195	6	GO:0031594
Domain	EGF_LAM_2	HSPG2 LAMA2 LAMA5 LAMB2 LAMB3	1.33e-05	30	194	5	PS50027
Domain	EGF_LAM_1	HSPG2 LAMA2 LAMA5 LAMB2 LAMB3	1.33e-05	30	194	5	PS01248
Domain	Laminin_N	LAMA2 LAMA5 LAMB2 LAMB3	1.86e-05	16	194	4	IPR008211
Domain	LamNT	LAMA2 LAMA5 LAMB2 LAMB3	1.86e-05	16	194	4	SM00136
Domain	LAMININ_NTER	LAMA2 LAMA5 LAMB2 LAMB3	1.86e-05	16	194	4	PS51117
Domain	Laminin_N	LAMA2 LAMA5 LAMB2 LAMB3	1.86e-05	16	194	4	PF00055
Domain	EGF_Lam	HSPG2 LAMA2 LAMA5 LAMB2 LAMB3	2.89e-05	35	194	5	SM00180
Domain	Laminin_EGF	HSPG2 LAMA2 LAMA5 LAMB2 LAMB3	2.89e-05	35	194	5	PF00053
Domain	Laminin_EGF	HSPG2 LAMA2 LAMA5 LAMB2 LAMB3	4.36e-05	38	194	5	IPR002049
Domain	LAMININ_IVA	HSPG2 LAMA2 LAMA5	5.95e-05	8	194	3	PS51115
Domain	Laminin_B	HSPG2 LAMA2 LAMA5	5.95e-05	8	194	3	PF00052
Domain	LamB	HSPG2 LAMA2 LAMA5	5.95e-05	8	194	3	SM00281
Domain	Laminin_IV	HSPG2 LAMA2 LAMA5	5.95e-05	8	194	3	IPR000034
Domain	Galactose-bd-like	ZZEF1 HERC2 LAMA2 LAMA5 LAMB2 LAMB3	4.44e-04	94	194	6	IPR008979
Pathway	REACTOME_LAMININ_INTERACTIONS	HSPG2 COL7A1 LAMA2 LAMA5 LAMB2 LAMB3	3.39e-07	30	135	6	M27216
Pathway	PID_INTEGRIN4_PATHWAY	LAMA2 LAMA5 LAMB2 LAMB3	2.52e-06	11	135	4	M158
Pathway	REACTOME_MRNA_EDITING	ADARB1 APOBEC3F APOBEC3D	6.92e-05	9	135	3	MM15445
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN5 ANK1 SPTBN4	9.81e-05	10	135	3	MM15112
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	GALNT3 KIF4A ZZEF1 PLXNB2 NCAPG2 DDOST PTK7 GGT7 JAG2 NUP210 A4GALT SEMA3B TMEM131L ECEL1 PLOD2 DNMT1 GPC1 HSPG2 COL7A1 LAMA5 LAMB2 LAMB3 TMEM43 SELENON TFRC THADA LRP5 G6PD	2.48e-10	1201	197	28	35696571
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LRRC24 UBL4A ZZEF1 PLXNB2 CNTROB GGT7 JAG2 ZFP36L2 A4GALT CACNA1H ATG9A HERC2 AGAP3 ANKRD13D HSPG2 TSNARE1 ZDHHC5 LAMA5 LAMB2 LAMB3 MED13L RASSF7 THADA LRP5 SPEN	4.52e-09	1105	197	25	35748872
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	HSPG2 COL7A1 LAMA2 LAMA5 LAMB2 LAMB3	1.30e-08	29	197	6	22613833
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	ABCF3 EPB41L3 PLXNB2 DDOST DDX3X CDC45 GMPS NUP210 AFG3L2 TMEM131L ECEL1 PLOD2 WDR77 HSPG2 LAMA5 LAMB2 TUT1 TFRC	1.59e-08	613	197	18	22268729
Pubmed	Basement membrane composition in the early mouse embryo day 7.	HSPG2 LAMA2 LAMA5 LAMB2 LAMB3	1.59e-08	15	197	5	15895400
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PNKP GALNT3 KIF4A DAXX ZFP36L2 WDR20 AFG3L2 FAM83D DLG3 NOL7 HERC2 ASCC3 WDR77 EXOSC4 AGAP3 NRDE2 DHX40 PUSL1 LAMA5 LAMB2 ABCB6 SPECC1L PIAS1 SIPA1L1 TAF5L SPEN TBL2	1.14e-07	1497	197	27	31527615
Pubmed	The snail superfamily of zinc-finger transcription factors.	SNAI3 SNAI2 SNAI1	1.79e-07	3	197	3	11994736
Pubmed	Snail family members unequally trigger EMT and thereby differ in their ability to promote the neoplastic transformation of mammary epithelial cells.	SNAI3 SNAI2 SNAI1	1.79e-07	3	197	3	24638100
Pubmed	Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.	LAMA2 LAMA5 LAMB2 LAMB3	2.04e-07	10	197	4	9034910
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TUBGCP4 ZZEF1 NCAPG2 DDOST DDX3X PTK7 CDC45 DSTYK AFG3L2 LRRC41 DNMT1 NRDE2 DHX40 LAMB3 PIAS1 MARF1 RAVER1	2.10e-07	650	197	17	38777146
Pubmed	A high-resolution molecular atlas of the fetal mouse lower urogenital tract.	EAF2 SNAI3 WDR77 DNMT1 SNAI2 LRP5 SNAI1	2.41e-07	75	197	7	21905163
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	SEMA3B HSPG2 COL7A1 LAMA2 LAMA5 LAMB2 LAMB3 LGALS4 ANGPTL6	2.47e-07	153	197	9	25037231
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMA2 LAMA5 LAMB2 LAMB3	3.19e-07	11	197	4	23472759
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMA2 LAMA5 LAMB2 LAMB3	3.19e-07	11	197	4	21524702
Pubmed	Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.	LAMA2 LAMA5 LAMB2 LAMB3	4.77e-07	12	197	4	9396756
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	PLXNB2 HSPG2 COL7A1 LAMA2 LAMA5 LAMB2 LAMB3 LGALS4 PLXDC2	5.17e-07	167	197	9	22159717
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	EVPL NCAPG2 DDOST PTK7 GGT7 CDC45 GMPS NUP210 AFG3L2 TMEM131L ASCC3 WDR77 DHX40 PUSL1 LAMB2 TMEM43 TFRC VANGL2 G6PD TBL2	8.01e-07	974	197	20	28675297
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMA2 LAMA5 LAMB2 LAMB3	1.72e-06	16	197	4	17601529
Pubmed	p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma.	SNAI3 SNAI2 SNAI1	1.78e-06	5	197	3	20385133
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	UBL4A PLXNB2 NCAPG2 DDOST PTK7 GGT7 JAG2 TRAFD1 NUP210 ASCC3 PLOD2 WNK3 DNMT1 TFRC JPH1 THADA IPO9 TBL2 RAVER1	1.99e-06	942	197	19	31073040
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	FRMPD4 AFG3L2 DLG3 SDK2 ZDHHC5 GRIA1 VANGL2 UBASH3B G6PD	2.05e-06	197	197	9	36604605
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PNKP GALNT3 MYO1C UBL4A TUBGCP4 NCAPG2 DDOST TRAFD1 NUP210 AFG3L2 ASCC3 PLOD2 WDR77 TMEM43 SPECC1L IDH3B TFRC THADA IPO9 SIPA1L1 EXOC1 G6PD TBL2 RAVER1	2.43e-06	1440	197	24	30833792
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	PNKP ABCF3 MYO1C KIF4A TUBGCP4 DDOST DDX3X GMPS BRAF AFG3L2 FAM83D ASCC3 WDR77 GPC1 SPECC1L IDH3B MED13L IPO9 SIPA1L1 G6PD TBL2 RAVER1	2.67e-06	1247	197	22	27684187
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ARHGAP32 PDE1B LRRC24 WDR81 KIF4A EPB41L3 DDX3X DLG3 HERC2 WNK3 DNMT1 TRIM46 GRIA1 SPECC1L GRM2 SPTBN4 SIPA1L1 APPL1 UBASH3B	2.74e-06	963	197	19	28671696
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMA2 LAMA5 LAMB2 LAMB3	2.87e-06	18	197	4	11311202
Pubmed	A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction.	LAMA2 LAMA5 LAMB2	3.54e-06	6	197	3	18817539
Pubmed	Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex.	SNAI3 SNAI2 SNAI1	3.54e-06	6	197	3	14673164
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	LAMA2 LAMA5 LAMB2 LAMB3	4.51e-06	20	197	4	22911573
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	NCAPG2 GMPS DNMT1 ARMC7 DHX40 TAF5L RAVER1	4.65e-06	116	197	7	30804394
Pubmed	PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.	HSPG2 COL7A1 LAMA5 LAMB3	5.54e-06	21	197	4	27856617
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	HSPG2 COL7A1 LAMA2 LAMA5 LAMB2 LAMB3	6.03e-06	79	197	6	18757743
Pubmed	Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor.	LAMA2 LAMB2 LAMB3	6.16e-06	7	197	3	9004048
Pubmed	Laminin isoforms in fetal and adult human adrenal cortex.	LAMA2 LAMA5 LAMB2	6.16e-06	7	197	3	14557481
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	MYO1C IMPG1 EPB41L3 PLXNB2 OLFML3 DDOST DDX3X PTK7 WDR20 PLOD2 HSPG2 ELOA LAMA5 LAMB2 TMEM43 IDH3B SELENON NARS2 TFRC SNED1 CATSPERG G6PD RAVER1	9.02e-06	1451	197	23	30550785
Pubmed	Expression and distribution of the zinc finger protein, SNAI3, in mouse ovaries and pre-implantation embryos.	SNAI3 SNAI2 SNAI1	9.82e-06	8	197	3	29445069
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	MYO1C EVPL DDOST DDX3X TASOR2 NUP210 AFG3L2 ASCC3 WDR77 EXOSC4 DNMT1 GPC1 ELOA LAMB3 TMEM43 SPECC1L TRMT6 SIPA1L1 SPEN TBL2 RAVER1	1.04e-05	1257	197	21	36526897
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ARHGAP32 EPB41L3 PLXNB2 WDR20 AGAP3 KIF26B ZDHHC5 TFRC VANGL2 JPH1 APPL1	1.14e-05	377	197	11	38117590
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	ACO1 NCAPG2 DDX3X GGT7 PLOD2 WNK3 LRRC41 AGAP3 NARS2 TFRC G6PD RAVER1	1.14e-05	451	197	12	36168627
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	ABCA3 UBL4A EPB41L3 PLXNB2 HERC2 LAMA5 LAMB2 TFRC IPO9 SPEN	1.32e-05	313	197	10	38270169
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	LAMA2 LAMA5 LAMB2 LAMB3	1.35e-05	26	197	4	24742657
Pubmed	A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice.	JAG2 VANGL2 SNAI2 SNAI1	1.58e-05	27	197	4	29956664
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	ABCF3 DAXX EPB41L3 RNF214 FAM83D ASCC3 WDR77 EXOSC4 NRDE2 SPECC1L MARF1 EXOC1 SPEN NSMCE4A RAVER1	1.82e-05	724	197	15	36232890
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	MYO1C OTUD1 UBL4A DDOST GMPS AFP WDR20 AFG3L2 HERC2 ASCC3 DNMT1 DHX40 HMX3 TUT1 IPO9 SIPA1L1 TAF5L TBL2	1.86e-05	1005	197	18	19615732
Pubmed	A human MAP kinase interactome.	ARHGAP32 EVPL DAXX EPB41L3 MAP3K4 BRAF HERC2 KIF26B LAMB2 SPECC1L PIAS1 CEP250	2.39e-05	486	197	12	20936779
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	UBL4A TUBGCP4 ZZEF1 DDOST DDX3X TRAFD1 NUP210 ATG9A HERC2 WDR77 TMEM43 TFRC THADA IPO9	2.56e-05	657	197	14	36180527
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	KIF4A UBL4A ZZEF1 HERC2 LRRC41 SPECC1L TRMT6 SIPA1L1	3.04e-05	212	197	8	33853758
Pubmed	Laminin 5 binds the NC-1 domain of type VII collagen.	COL7A1 LAMA5	3.19e-05	2	197	2	9245798
Pubmed	Transferrin receptor induction in Toxoplasma gondii-infected HFF is associated with increased iron-responsive protein 1 activity and is mediated by secreted factors.	ACO1 TFRC	3.19e-05	2	197	2	15349772
Pubmed	Snai2 and Snai3 transcriptionally regulate cellular fitness and functionality of T cell lineages through distinct gene programs.	SNAI3 SNAI2	3.19e-05	2	197	2	26831822
Pubmed	The expression pattern of laminin isoforms in Hirschsprung disease reveals a distal peripheral nerve differentiation.	LAMA2 LAMA5	3.19e-05	2	197	2	16226104
Pubmed	Conserved and divergent roles for members of the Snail family of transcription factors in the chick and mouse embryo.	SNAI2 SNAI1	3.19e-05	2	197	2	9671584
Pubmed	SNAI1 and SNAI2 are asymmetrically expressed at the 2-cell stage and become segregated to the TE in the mouse blastocyst.	SNAI2 SNAI1	3.19e-05	2	197	2	20046880
Pubmed	Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion.	SNAI2 SNAI1	3.19e-05	2	197	2	23618854
Pubmed	[The expression of TfR1 mRNA and IRP1 mRNA in the placenta from different maternal iron status].	ACO1 TFRC	3.19e-05	2	197	2	17877204
Pubmed	'Snail factors in testicular germ cell tumours and their regulation by the BMP4 signalling pathway'.	SNAI2 SNAI1	3.19e-05	2	197	2	32441446
Pubmed	Cardiac Involvement in LAMA2-Related Muscular Dystrophy and SELENON-Related Congenital Myopathy: A Case Series.	LAMA2 SELENON	3.19e-05	2	197	2	39177608
Pubmed	The SNAI1 and SNAI2 proteins occupy their own and each other's promoter during chondrogenesis.	SNAI2 SNAI1	3.19e-05	2	197	2	23665016
Pubmed	Clinical significance of LAMB3 and COL7A1 mRNA in esophageal squamous cell carcinoma.	COL7A1 LAMB3	3.19e-05	2	197	2	18331784
Pubmed	GALNT3 Maintains the Epithelial State in Trophoblast Stem Cells.	GALNT3 MAP3K4	3.19e-05	2	197	2	30917321
Pubmed	Oncogenic BRAFV600E drives expression of MGL ligands in the colorectal cancer cell line HT29 through N-acetylgalactosamine-transferase 3.	GALNT3 BRAF	3.19e-05	2	197	2	29894293
Pubmed	DAL-1/4.1B promotes the uptake of exosomes in lung cancer cells via Heparan Sulfate Proteoglycan 2 (HSPG2).	EPB41L3 HSPG2	3.19e-05	2	197	2	34657240
Pubmed	Slug and Snail have differential effects in directing colonic epithelial wound healing and partially mediate the restitutive effects of butyrate.	SNAI2 SNAI1	3.19e-05	2	197	2	31393789
Pubmed	Snail is an independent prognostic predictor for progression and patient survival of gastric cancer.	SNAI2 SNAI1	3.19e-05	2	197	2	22471696
Pubmed	Mammalian BarH1 confers commissural neuron identity on dorsal cells in the spinal cord.	BARHL1 BARHL2	3.19e-05	2	197	2	12657654
Pubmed	Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer.	SNAI2 SNAI1	3.19e-05	2	197	2	19502595
Pubmed	[SNAI1 and SNAI2 - transcriptional master-regulators of epithelial-mesenchimal transition].	SNAI2 SNAI1	3.19e-05	2	197	2	26571812
Pubmed	The SUMO ligase PIAS1 regulates UV-induced apoptosis by recruiting Daxx to SUMOylated foci.	DAXX PIAS1	3.19e-05	2	197	2	22976298
Pubmed	Candidate human genetic polymorphisms and severe malaria in a Tanzanian population.	CD40LG G6PD	3.19e-05	2	197	2	23144702
Pubmed	[Association between the polymorphisms of TMPRSS6 and the levels of serum ferrtin and soluble transferrin receptor in pregnant women in Lüliang Area of Shanxi Province].	TMPRSS6 TFRC	3.19e-05	2	197	2	30593316
Pubmed	Identification and analysis of two snail genes in the pufferfish (Fugu rubripes) and mapping of human SNA to 20q.	SNAI2 SNAI1	3.19e-05	2	197	2	10773451
Pubmed	Tumor-induced upregulation of Twist, Snail, and Slug represses the activity of the human VE-cadherin promoter.	SNAI2 SNAI1	3.19e-05	2	197	2	19046938
Pubmed	Identification of genes showing differential expression in anorexia mutant mouse.	TYRO3 GRIA1	3.19e-05	2	197	2	12802202
Pubmed	Impact of Selected Signaling Proteins on SNAIL 1 and SNAIL 2 Expression in Ovarian Cancer Cell Lines in Relation to Cells' Cisplatin Resistance and EMT Markers Level.	SNAI2 SNAI1	3.19e-05	2	197	2	33478150
Pubmed	Distinct EMT programs control normal mammary stem cells and tumour-initiating cells.	SNAI2 SNAI1	3.19e-05	2	197	2	26331542
Pubmed	Genetic analysis of epidermolysis bullosa: identification of mutations in LAMB3 and COL7A1 genes in three families.	COL7A1 LAMB3	3.19e-05	2	197	2	23769655
Pubmed	Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice.	SNAI2 SNAI1	3.19e-05	2	197	2	38451818
Pubmed	Expression of Snail protein in tumor-stroma interface.	SNAI3 SNAI1	3.19e-05	2	197	2	16568079
Pubmed	Expression and localization of transcription factors SNAIL and SLUG in mouse ovaries and pre-implantation embryos.	SNAI2 SNAI1	3.19e-05	2	197	2	25092544
Pubmed	Modularity and reshuffling of Snail and Slug expression during vertebrate evolution.	SNAI2 SNAI1	3.19e-05	2	197	2	12482931
Pubmed	Snail family transcription factors are implicated in thyroid carcinogenesis.	SNAI2 SNAI1	3.19e-05	2	197	2	17724139
Pubmed	Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2.	NR1H3 SNAI2	3.19e-05	2	197	2	38016947
Pubmed	Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines.	SNAI2 SNAI1	3.19e-05	2	197	2	18408755
Pubmed	SNAIL Transctiption factor in prostate cancer cells promotes neurite outgrowth.	SNAI2 SNAI1	3.19e-05	2	197	2	33132158
Pubmed	Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin.	HELB CDC45	3.19e-05	2	197	2	25933514
Pubmed	Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress.	SNAI2 SNAI1	3.19e-05	2	197	2	15314165
Pubmed	Type VII collagen is required for Ras-driven human epidermal tumorigenesis.	COL7A1 LAMA5	3.19e-05	2	197	2	15774758
Pubmed	OGG1 promoted lung fibrosis by activating fibroblasts via interacting with Snail1.	OGG1 SNAI1	3.19e-05	2	197	2	37977070
Pubmed	Determination of the substrate specificity of protein-tyrosine phosphatase TULA-2 and identification of Syk as a TULA-2 substrate.	SYK UBASH3B	3.19e-05	2	197	2	20670933
Pubmed	The transcriptional repressor Snail promotes mammary tumor recurrence.	SNAI2 SNAI1	3.19e-05	2	197	2	16169465
Pubmed	Expression of Snail and Slug in renal cell carcinoma: E-cadherin repressor Snail is associated with cancer invasion and prognosis.	SNAI2 SNAI1	3.19e-05	2	197	2	21808237
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	SPTBN5 NUP210 AGAP3 ANKRD13D HSPG2 LAMA5 IPO9 LRP5	3.25e-05	214	197	8	22199357
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ARHGAP32 EPB41L3 DDX3X BRAF ZFP36L2 STARD9 DSTYK WNK3 DNMT1 AGAP3 KIF26B FSD1 RASSF7 NARS2 IPO9 SIPA1L1	3.55e-05	861	197	16	36931259
Pubmed	Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development.	SNAI3 SNAI2 SNAI1	3.79e-05	12	197	3	21287656
Pubmed	miRNAs control tracheal chondrocyte differentiation.	SNAI2 SNAI1 SPEN	3.79e-05	12	197	3	21945074
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	HSPG2 LAMA2 LAMA5	3.79e-05	12	197	3	16750824
Pubmed	PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates.	PTK7 PLOD2 VANGL2	3.79e-05	12	197	3	15229603
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	NUP210 PLOD2 HSPG2 LAMA5 LAMB2 LAMB3 TFRC	4.42e-05	164	197	7	32409323
Pubmed	Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis.	HSPG2 COL7A1 LAMA5 SNAI2	4.56e-05	35	197	4	18676816
Pubmed	Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.	ZZEF1 DDOST NUP210 AFG3L2 TMEM43 TFRC	4.68e-05	113	197	6	30352685
Pubmed	The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.	LAMA2 LAMA5 LAMB2	4.91e-05	13	197	3	36350252
Interaction	EDN3 interactions	JAG2 DSTYK SEMA3B HSPG2 LAMA5 LAMB2 LAMB3 SELENON LRP5	9.72e-07	108	193	9	int:EDN3
Interaction	ANTXR2 interactions	ALOX12B ANKRD13D ELOA RAB25 SPTBN4	7.54e-06	29	193	5	int:ANTXR2
Interaction	SIRPD interactions	JAG2 SEMA3B HSPG2 LAMA5 LAMB2 SELENON LRP5	1.88e-05	86	193	7	int:SIRPD
Interaction	DNAJB9 interactions	TMPRSS13 DDOST NUP210 SEMA3B ECEL1 LAMA5 LAMB3 TMEM43 PLXDC2 LRP5	2.61e-05	202	193	10	int:DNAJB9
Interaction	IL5RA interactions	PLXNB2 SEMA3B HSPG2 LAMA5 LAMB2 LAMB3 SELENON LRP5	2.61e-05	124	193	8	int:IL5RA
GeneFamily	Laminin subunits	LAMA2 LAMA5 LAMB2 LAMB3	1.62e-06	12	140	4	626
GeneFamily	Zinc fingers C2H2-type\|SNAG transcriptional repressors	SNAI3 SNAI2 SNAI1	5.24e-05	10	140	3	1259
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN5 SPTBN4	1.22e-03	7	140	2	1113
GeneFamily	Blood group antigens\|CD molecules\|Proteoglycans	HSPG2 SRGN	1.22e-03	7	140	2	570
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	LRRC24 LINGO3 PTK7 TYRO3 HSPG2 SDK2	1.60e-03	161	140	6	593
Coexpression	HEBERT_MATRISOME_TNBC_LUNG_METASTASIS	HSPG2 COL7A1 LAMA5 LAMB2 LAMB3	6.87e-07	23	197	5	M48001
Coexpression	NABA_BASEMENT_MEMBRANES	HSPG2 LAMA2 LAMA5 LAMB2 LAMB3	1.21e-05	40	197	5	M5887
Coexpression	NABA_MATRISOME_BLEO_FIBROTIC_LUNG	HSPG2 LAMA5 LAMB2 LAMB3	1.36e-05	20	197	4	MM17053
Coexpression	GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN	ARHGAP32 ZNF229 ADARB1 TMEM71 APOBEC3F BRAF APOBEC3D DHX40 SIPA1L1	2.01e-05	198	197	9	M9234
Coexpression	GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_DN	ABCA3 ZZEF1 RNF214 ANKRD13D NRDE2 COL7A1 VANGL2 ZMAT3 TBL2	2.18e-05	200	197	9	M6208
Coexpression	GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP	PNKP PLXNB2 ZFP36L2 STARD9 WDR20 MED11 NOL7 HERC2 G6PD	2.18e-05	200	197	9	M6044
Coexpression	GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN	ARHGAP32 ACO1 PLXNB2 OLFML3 EXOC3L4 NR1H3 FSD1 MARF1 SPEN	2.18e-05	200	197	9	M6610
Coexpression	FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS	ZNF423 WDR81 SYNC PLXNB2 SEMA3B ASCC3 GPC1 COL7A1 ABCB6 ZMAT3 MARF1	2.55e-05	311	197	11	M61
Coexpression	GRYDER_PAX3FOXO1_TOP_ENHANCERS	ZZEF1 NCAPG2 DDOST HELB RMI1 TMEM131L FAM83D HSPG2 LAMB3 MED13L SELENON VANGL2 APPL1	3.19e-05	441	197	13	M172
Coexpression	NABA_CORE_MATRISOME	IMPG1 HSPG2 COL7A1 LAMA2 LAMA5 LAMB2 LAMB3 SNED1 SRGN RSPO2	4.05e-05	270	197	10	MM17057
Coexpression	NABA_CORE_MATRISOME	IMPG1 HSPG2 COL7A1 LAMA2 LAMA5 LAMB2 LAMB3 SNED1 SRGN RSPO2	4.73e-05	275	197	10	M5884
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN	PDE1B PEX13 DDX3X RYR3 STARD9 FAM181B KIF26B GRIA1 MED13L ANGPTL6 RSPO2 UBASH3B	7.06e-05	411	197	12	M1351
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN	PDE1B PEX13 DDX3X RYR3 STARD9 FAM181B KIF26B GRIA1 MED13L ANGPTL6 RSPO2 UBASH3B	7.91e-05	416	197	12	MM1002
Coexpression	NABA_MATRISOME	IMPG1 PLXNB2 SEMA3B ITIH6 PLOD2 GPC1 HSPG2 COL7A1 WNT9A LAMA2 LAMA5 LAMB2 LAMB3 LGALS4 SNED1 ANGPTL6 PLXDC2 SRGN RSPO2 CLCF1	9.97e-05	1026	197	20	M5889
Coexpression	MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	GALNT3 WDR20 DISP3 KIF26B JPH1 RSPO2 CSMD1	1.08e-04	143	197	7	M1935
Coexpression	MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	GALNT3 WDR20 DISP3 KIF26B JPH1 RSPO2 CSMD1	1.08e-04	143	197	7	MM819
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYCP2L ZNF423 WDR81 JAG2 TRANK1 BRAF WDR20 TMEM131L CEP250 TAF5L	1.31e-08	189	197	10	bccb3481ffed597c845fe860da658505316105b5
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRMPD4 ZNF423 ADARB1 NCAPG2 OLFML3 SPECC1L PLXDC2 SNAI2 SNAI1	9.52e-08	176	197	9	cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	EVPL SEMA3B CACNA1H TMPRSS6 LAMA5 LAMB2 LAMB3 LRP5	1.02e-06	172	197	8	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADARB1 OLFML3 SDK2 NR1H3 PLXDC2 SNAI2 RSPO2 SNAI1	1.38e-06	179	197	8	b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA13 EPB41L3 ANKRD34B SEMA3B PLOD2 HSPG2 LAMB3 RASSF7	1.56e-06	182	197	8	573771130247e869e4e58f22d4a1cb31989635cf
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA13 EPB41L3 ANKRD34B SEMA3B PLOD2 HSPG2 LAMB3 RASSF7	1.56e-06	182	197	8	6cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 ABCA13 RYR3 TRANK1 DISP3 ANK1 KIF26B CSMD1	1.70e-06	184	197	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 ABCA13 RYR3 TRANK1 DISP3 ANK1 KIF26B CSMD1	1.70e-06	184	197	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 ABCA13 RYR3 TRANK1 DISP3 ANK1 KIF26B CSMD1	1.70e-06	184	197	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	Basal_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	JAG2 A4GALT GPC1 COL7A1 SDK2 LAMA5 LAMB3 SNAI2	2.24e-06	191	197	8	a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 PTK7 LAMA2 GRIA1 PLXDC2 SNAI2 SNAI1	2.42e-06	193	197	8	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 PTK7 LAMA2 GRIA1 PLXDC2 SNAI2 SNAI1	2.42e-06	193	197	8	ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRMPD4 ADARB1 SDK2 KIF26B GRIA1 SNED1 PLXDC2 RSPO2	2.51e-06	194	197	8	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 SDK2 GRIA1 SPECC1L SNED1 PLXDC2 SNAI2	2.61e-06	195	197	8	3a0cad69cfc150a27a0666f612f5294c817197d7
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	EPB41L3 SYK KCNK13 TFRC PLXDC2 SRGN SIPA1L1 UBASH3B	2.61e-06	195	197	8	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 SDK2 GRIA1 SPECC1L SNED1 PLXDC2 SNAI2	2.61e-06	195	197	8	2b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCell	Epithelial_cells-AT1_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	MYO1C OTUD1 EPB41L3 SEMA3B HSPG2 LAMA5 LAMB2 LAMB3	2.71e-06	196	197	8	6c99d29162848161c1f166a032320f87a5d5a631
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GALNT3 EVPL TC2N NUP210 SYK RAB25 LAMB3 RASSF7	2.71e-06	196	197	8	7b17d47b7758d8ccf9dbefd097aeb553791a1eed
ToppCell	Basal_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	JAG2 GPC1 COL7A1 SDK2 LAMA5 LAMB3 VANGL2 SNAI2	2.71e-06	196	197	8	3b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	JAG2 GPC1 COL7A1 SDK2 LAMA5 LAMB3 VANGL2 SNAI2	2.82e-06	197	197	8	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	distal-2-Epithelial-Basal\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FRMPD4 PTK7 SEMA3B GPC1 COL7A1 RAB25 SH2D3A LAMB3	3.15e-06	200	197	8	9beb128841c50241aa819261f21bf66f881ea125
ToppCell	PBMC-Mild-cDC_7\|Mild / Compartment, Disease Groups and Clusters	EVPL APOBEC3F ACSM5 PLOD2 NR1H3 LRP5 SNAI1	3.35e-06	142	197	7	58f66f35646f281e64d634e6c26adbd1d4e6c830
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	OLFML3 PTK7 AMIGO3 GPC1 KIF26B SNAI2 SNAI1	7.05e-06	159	197	7	b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FRMPD4 JAG2 GPC1 COL7A1 LAMB3 SNAI2 CSMD1	1.09e-05	170	197	7	0cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FRMPD4 JAG2 GPC1 COL7A1 LAMB3 SNAI2 CSMD1	1.09e-05	170	197	7	2d880223d01bde4bf777bd6f50b7d2768489075f
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ARHGAP32 LINGO3 SPTBN5 PRRT3 ARMC7 RAB25 LAMA5	1.13e-05	171	197	7	943fbca8a6ac04052a2a85aca7b21a3461cd96f7
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 TYRO3 MED11 CACNA1H ATG9A TRIM46 LAMA5	1.27e-05	174	197	7	c58328c2f262506a4518f49f148e29874faf9171
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RYR3 PTK7 TC2N CACNA1H SDK2 VANGL2 RSPO2	1.32e-05	175	197	7	90e29945aa861082c94bb4f331161adc3a6ef899
ToppCell	AT1_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	MYO1C TMPRSS13 SEMA3B HSPG2 WNT9A LAMA5 LAMB3	1.37e-05	176	197	7	4a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPB41L3 SEMA3B PLOD2 WNK3 HSPG2 LAMB3 JPH1	1.42e-05	177	197	7	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	COPD-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	FRMPD4 TMEM71 JAG2 COL7A1 LAMB3 PLXDC2 SNAI2	1.47e-05	178	197	7	441d1dba720141891b11f404744c59834d80e6c5
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	OLFML3 SDK2 SPECC1L SNED1 PLXDC2 SNAI2 SNAI1	1.52e-05	179	197	7	948c2a01ec7a626c68281e6e796a9f0527a88591
ToppCell	Control-Epithelial_alveolar-AT_1-AT1-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPB41L3 SEMA3B ECEL1 PLOD2 RAB25 LAMB3 RASSF7	1.70e-05	182	197	7	a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-AT1-AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 EPB41L3 TC2N SEMA3B RAB25 LAMB3 RASSF7	1.70e-05	182	197	7	cc79e0cc21e2fdc4ef77f052818d27b9f707aec1
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3B ECEL1 GPC1 HSPG2 SDK2 TMPRSS6 CSMD1	1.70e-05	182	197	7	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	Basal\|World / shred by cell class for mouse tongue	ADARB1 PTK7 JAG2 COL7A1 LAMA5 LAMB3 SNAI2	1.76e-05	183	197	7	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCA3 EVPL SEMA3B WNT9A LAMA5 LAMB3 RASSF7	1.76e-05	183	197	7	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYCP2L ZNF423 CDC45 STARD9 HSPG2 SNED1 FAR2	1.82e-05	184	197	7	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	ABCF3 FAM83D GPC1 COL7A1 SDK2 VANGL2 SNAI2	1.82e-05	184	197	7	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 EPB41L3 TC2N SEMA3B RAB25 LAMB3 RASSF7	1.82e-05	184	197	7	cdf6f1c6cce97a7effa0c55959652e2c0b6992b3
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 EPB41L3 TC2N SEMA3B RAB25 LAMB3 RASSF7	1.89e-05	185	197	7	0c247a3f394c42e2a6f67fee3d9cf33096fecd13
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADARB1 OLFML3 PTK7 LAMA2 GRIA1 SPECC1L PLXDC2	1.95e-05	186	197	7	1ed71b229f40a680071b14f5a7a19706e0fd14b1
ToppCell	droplet-Fat-Scat-21m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 TMPRSS13 TRIM46 RAB25 TMPRSS6 LAMB3 RASSF7	1.95e-05	186	197	7	de88fafac51049ec1920695844d8ce8057940272
ToppCell	droplet-Fat-Scat-21m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 TMPRSS13 TRIM46 RAB25 TMPRSS6 LAMB3 RASSF7	1.95e-05	186	197	7	7ff73ab8fed5da779ee9c7bd2e14a8363edb7509
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADARB1 OLFML3 PTK7 LAMA2 GRIA1 SPECC1L PLXDC2	1.95e-05	186	197	7	ca5e9c6531cb5d199e27509bfab1d62e3937177e
ToppCell	droplet-Fat-Scat-21m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 TMPRSS13 TRIM46 RAB25 TMPRSS6 LAMB3 RASSF7	1.95e-05	186	197	7	59710cff3f6f7c318ee2524b44c1a909f312c25e
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 EPB41L3 TC2N SEMA3B TRIM46 SDK2 LAMB3	1.95e-05	186	197	7	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	LPS_only-Epithelial_alveolar-AT_1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 EPB41L3 TC2N SEMA3B RAB25 LAMB3 RASSF7	2.02e-05	187	197	7	ff26a533d310126521efe1d05cf8b9d32e524550
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF4A NCAPG2 CDC45 ANK1 TMPRSS6 ABCB6 TFRC	2.02e-05	187	197	7	dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCell	Mesenchymal_cells-Osteoblasts\|World / Lineage and Cell class	GALNT3 SEMA3B CREB3L3 PLOD2 GPC1 SDK2 FHOD3	2.09e-05	188	197	7	89f7f5a51be7e046a63e2413f86c521ae4b6718f
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ADARB1 OLFML3 PTK7 GPC1 SPECC1L PLXDC2 SNAI2	2.16e-05	189	197	7	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma\|TCGA-Lung / Sample_Type by Project: Shred V9	ABCF3 CDC45 GMPS FAM83D GPC1 COL7A1 SNAI2	2.16e-05	189	197	7	aa4f7d7a5196e5ae481ebc2549de8e3f0ef6e6be
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ADARB1 OLFML3 PTK7 GPC1 SPECC1L PLXDC2 SNAI2	2.24e-05	190	197	7	1196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ADARB1 OLFML3 SETD4 SPECC1L PLXDC2 SNAI2 SNAI1	2.31e-05	191	197	7	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	AT1_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	MYO1C SEMA3B HSPG2 WNT9A LAMA5 LAMB2 LAMB3	2.39e-05	192	197	7	0444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCell	PND14-Mesenchymal-Mesenchymal_structural\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 GRIA1 SPECC1L SNED1 PLXDC2 SNAI2	2.39e-05	192	197	7	25492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 GRIA1 SPECC1L SNED1 PLXDC2 SNAI2	2.39e-05	192	197	7	de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	ADARB1 PTK7 SDK2 KIF26B GRIA1 PLXDC2 SRGN	2.39e-05	192	197	7	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 SPECC1L SNED1 PLXDC2 SNAI2 RSPO2	2.47e-05	193	197	7	8d05805295c5d3aa93aeb38be5fbefa81e1be1f0
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ABCA3 RAB25 TMPRSS6 LAMA5 LAMB3 RASSF7 TFRC	2.47e-05	193	197	7	c1817ad675b9f9d2d3436c8b9646edf89f0d4c82
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML3 PLOD2 HSPG2 CHODL TMPRSS6 LAMA2 PLXDC2	2.47e-05	193	197	7	eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML3 PLOD2 HSPG2 TMPRSS6 LAMA2 LAMB2 PLXDC2	2.47e-05	193	197	7	428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 SPECC1L SNED1 PLXDC2 SNAI2 RSPO2	2.47e-05	193	197	7	1b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCell	RA-08._Macrophage\|World / Chamber and Cluster_Paper	EPB41L3 SYK TFRC PLXDC2 SRGN SIPA1L1 UBASH3B	2.47e-05	193	197	7	5fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCell	E16.5-samps-Epithelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ABCA3 RAB25 TMPRSS6 LAMA5 LAMB3 RASSF7 TFRC	2.47e-05	193	197	7	1cb5a1cffa2b4a3bfecca16b791c1992edeb237d
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADARB1 SDK2 LAMA2 GRIA1 SNED1 PLXDC2 RSPO2	2.56e-05	194	197	7	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GALNT3 EVPL TC2N NUP210 RAB25 LAMB3 RASSF7	2.56e-05	194	197	7	c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCell	COPD-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	EPB41L3 NRDE2 TFRC PLXDC2 SIPA1L1 UBASH3B CSMD1	2.56e-05	194	197	7	7d682408e9a6239a4e47befc9376e760cc3d133a
ToppCell	LA-08._Macrophage\|World / Chamber and Cluster_Paper	EPB41L3 SYK TFRC PLXDC2 SRGN SIPA1L1 UBASH3B	2.56e-05	194	197	7	c1805572bcc11b1cd29083329d7b5911489fb758
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CNTROB NCAPG2 CDC45 PRRT3 CACNA1H RAB25 CLCF1	2.56e-05	194	197	7	5031f324628ff12a33e84cc52157be4786e0961d
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRMPD4 ADARB1 SDK2 GRIA1 SNED1 PLXDC2 RSPO2	2.56e-05	194	197	7	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	RA-08._Macrophage\|RA / Chamber and Cluster_Paper	EPB41L3 SYK TFRC PLXDC2 SRGN SIPA1L1 UBASH3B	2.56e-05	194	197	7	ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 SPECC1L SNED1 PLXDC2 SNAI2 RSPO2	2.64e-05	195	197	7	1c1135be421af98cd0077bec1ff2c4158d42aa21
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 SPECC1L SNED1 PLXDC2 SNAI2 SNAI1	2.64e-05	195	197	7	598b69032a8441a23749b27863d80f7a1fc82a96
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 SPECC1L SNED1 PLXDC2 SNAI2 RSPO2	2.64e-05	195	197	7	1f005ee1da66b539bd200aaa98f46edbbc7f12e4
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 SPECC1L SNED1 PLXDC2 SNAI2 SNAI1	2.64e-05	195	197	7	8aa753934debffe5ae4b5eecb6b50c46d17cc3ec
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF423 RYR3 CC2D2B JAG2 HSPG2 SNED1 SRGN	2.64e-05	195	197	7	77e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LAMA2 SNED1 PLXDC2 SNAI2 PTCH2 RSPO2 UBASH3B	2.64e-05	195	197	7	c5d2d9f12fd893331c9de261af30607d845d4f6a
ToppCell	AT1_cells\|World / lung cells shred on cell class, cell subclass, sample id	MYO1C SEMA3B HSPG2 WNT9A LAMA5 LAMB2 LAMB3	2.64e-05	195	197	7	792d6a49b0a875a00569071183d195287a9925c5
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML3 ASCC3 CHODL TMPRSS6 LAMA2 JPH1 PLXDC2	2.64e-05	195	197	7	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF423 ADARB1 RYR3 STARD9 HSPG2 SNED1 FAR2	2.73e-05	196	197	7	8ad8efb631164b46f0c082572270188e5ead20bf
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADARB1 OLFML3 CHODL SPECC1L SNED1 PLXDC2 SNAI2	2.73e-05	196	197	7	14246f00c90741a5f8683f377e22e3a7c99661b9
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ADARB1 OLFML3 ZFP36L2 SDK2 PLXDC2 SRGN RSPO2	2.73e-05	196	197	7	6730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ADARB1 OLFML3 ZFP36L2 SDK2 PLXDC2 SRGN RSPO2	2.73e-05	196	197	7	21dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLXNB2 RYR3 ASIC4 GPC1 LAMA5 LAMB2 CLCF1	2.73e-05	196	197	7	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF423 ADARB1 RYR3 STARD9 HSPG2 SNED1 FAR2	2.73e-05	196	197	7	9606ea7e42f707e69ea891b3521037613b9675f5
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EPB41L3 SYK KCNK13 TFRC PLXDC2 SRGN UBASH3B	2.73e-05	196	197	7	7026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell	severe-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ABCA13 KIF4A NCAPG2 COL7A1 GRM2 FAR2 SRGN	2.82e-05	197	197	7	70704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ABCA3 GALNT3 AMIGO3 ECEL1 RAB25 LAMB3 TFRC	2.82e-05	197	197	7	1638959d7aecb9fc5285eb7e4a3103ca437989e2
ToppCell	AT1_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	MYO1C SEMA3B HSPG2 WNT9A LAMA5 LAMB2 LAMB3	2.82e-05	197	197	7	80d81be244c94c435accb643449b4ce6a3462c7f
ToppCell	Children_(3_yrs)-Immune\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SYK TMEM131L TFRC FAR2 PLXDC2 SRGN UBASH3B	2.82e-05	197	197	7	f18807124b91310fcd84238484a80ecdba684679
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	EAF2 EPB41L3 SYK KCNK13 TFRC PLXDC2 SRGN	2.82e-05	197	197	7	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	Sepsis-Bac-SEP-Lymphocyte-T/NK-MAIT\|Bac-SEP / Disease, condition lineage and cell class	SPTBN5 TYRO3 TC2N ZFP36L2 DLG3 LAMA2 CD40LG	2.91e-05	198	197	7	aea3654b16785aa9857ed646bd0d0dc9724df364
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYCP2L ZNF423 RYR3 STARD9 HSPG2 SNED1 FAR2	2.91e-05	198	197	7	0a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADARB1 KIF26B LAMA2 GRIA1 SNED1 PLXDC2 RSPO2	2.91e-05	198	197	7	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	Epithelial_cells-Basal_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	JAG2 ZFP36L2 A4GALT GPC1 COL7A1 SDK2 SNAI2	2.91e-05	198	197	7	4235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 JAG2 COL7A1 LAMA5 LAMB3 FHOD3 CSMD1	3.01e-05	199	197	7	94a7867e800df352731796de8c24cba133c29622
ToppCell	medial-Epithelial-Basal-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FRMPD4 GPC1 COL7A1 RAB25 SH2D3A LAMB3 FHOD3	3.01e-05	199	197	7	fc37f8868417308fb4410684d0d1e506cec30f35
ToppCell	medial-2-Epithelial-Basal\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FRMPD4 GPC1 COL7A1 RAB25 SH2D3A LAMB3 FHOD3	3.01e-05	199	197	7	10af93596cc6d5da4cf5052707ff5f7fc347dc84
ToppCell	medial-Epithelial-Basal\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FRMPD4 GPC1 COL7A1 RAB25 SH2D3A LAMB3 FHOD3	3.01e-05	199	197	7	fa7584e3cc0f8cbdd6a76c6a0faee26b0922c4ae
Disease	Malignant neoplasm of breast	ABCA3 EPB41L3 DDX3X JAG2 BRAF AFP HERC2 DNMT1 GPC1 COL7A1 ANK1 PCDHGB6 TMPRSS6 SH2D3A LAMA2 ABCB6 TRAPPC8 TFRC PRICKLE3 SIPA1L1 SNAI2 APPL1 SNAI1 SPEN	2.04e-07	1074	195	24	C0006142
Disease	hemoglobin measurement, hemoglobin A1 measurement	UBL4A G6PD	1.30e-04	3	195	2	EFO_0004509, EFO_0007629
Disease	Macrostomia	SPECC1L PTCH2	2.58e-04	4	195	2	C0024433
Disease	Iron deficiency anemia	TMPRSS6 TFRC	2.58e-04	4	195	2	C0162316
Disease	hepatitis (biomarker_via_orthology)	AFP OGG1	2.58e-04	4	195	2	DOID:2237 (biomarker_via_orthology)
Disease	polymyositis	SLC26A1 SDK2 LRP5	2.98e-04	20	195	3	EFO_0003063
Disease	autosomal recessive limb-girdle muscular dystrophy (is_implicated_in)	JAG2 LAMA2	4.29e-04	5	195	2	DOID:0110274 (is_implicated_in)
Disease	Familial Nonmedullary Thyroid Cancer	BRAF WDR20 SNAI2 SNAI1	7.19e-04	61	195	4	C3501844
Disease	Nonmedullary Thyroid Carcinoma	BRAF WDR20 SNAI2 SNAI1	7.19e-04	61	195	4	C3501843
Disease	cutaneous melanoma, hair color	PLXNB2 DSTYK HERC2 MED13L	7.65e-04	62	195	4	EFO_0000389, EFO_0003924
Disease	hepatocellular carcinoma (biomarker_via_orthology)	GMPS AFP DNMT1 TFRC G6PD	7.70e-04	108	195	5	DOID:684 (biomarker_via_orthology)
Disease	carcinoma (implicated_via_orthology)	SNAI3 DLG3 SNAI2 SNAI1	8.62e-04	64	195	4	DOID:305 (implicated_via_orthology)
Disease	arachidonate 15-lipoxygenase B measurement	CNTROB GUCY2D	8.93e-04	7	195	2	EFO_0801391
Disease	Breast Carcinoma	EPB41L3 JAG2 BRAF AFP HERC2 DNMT1 COL7A1 PCDHGB6 TFRC SNAI2 SNAI1	9.62e-04	538	195	11	C0678222
Disease	creatinine measurement	EPB41L3 PLXNB2 GGT7 JAG2 ZFP36L2 TMEM131L ASIC4 ASCC3 EXOSC4 TRIM46 KIF26B DHX40 LAMA2 LAMA5 NR1H3 PLXDC2	9.93e-04	995	195	16	EFO_0004518
Disease	Muscular Dystrophy	LAMA2 SELENON	1.19e-03	8	195	2	C0026850
Disease	Lymphoma, Non-Hodgkin	BRAF TFRC SPEN	1.22e-03	32	195	3	C0024305
Disease	cutaneous melanoma	PLXNB2 TASOR2 DSTYK HERC2 MED13L	1.28e-03	121	195	5	EFO_0000389
Disease	mean platelet volume	ARHGAP32 MYO1C TRANK1 DSTYK EXOC3L4 A4GALT SYK TMEM131L DLG3 PCDHGB6 ZMAT3 FAR2 PRICKLE3 UBASH3B CATSPERG SEC14L5	1.28e-03	1020	195	16	EFO_0004584
Disease	non-syndromic X-linked intellectual disability (implicated_via_orthology)	DLG3 THADA	1.52e-03	9	195	2	DOID:0050776 (implicated_via_orthology)
Disease	platelet crit	NCAPG2 TRAFD1 EXOC3L4 WDR20 A4GALT SYK TMEM131L TMPRSS6 LAMA5 PIAS1 ZMAT3 THADA CD40LG UBASH3B RAVER1	1.74e-03	952	195	15	EFO_0007985
Disease	high density lipoprotein cholesterol measurement, multiple sclerosis	SYK UBASH3B	1.89e-03	10	195	2	EFO_0004612, MONDO_0005301
Disease	Graves' disease (is_implicated_in)	DNMT1 OGG1 CD40LG	2.18e-03	39	195	3	DOID:12361 (is_implicated_in)
Disease	Neuroendocrine Tumors	DAXX BRAF	2.30e-03	11	195	2	C0206754
Disease	immature reticulocyte measurement	TMPRSS6 TFRC LRP5	2.35e-03	40	195	3	EFO_0803545
Disease	response to simvastatin, myopathy	ABCA13 TBC1D21 FAR2	2.52e-03	41	195	3	EFO_0004145, GO_1903491
Disease	Colorectal Neoplasms	ABCA3 ABCA13 BRAF ZFP36L2 COL7A1 ABCB6 TFRC	2.55e-03	277	195	7	C0009404
Disease	Papillary thyroid carcinoma	BRAF WDR20 SNAI2 SNAI1	2.57e-03	86	195	4	C0238463
Disease	Sclerocystic Ovaries	ADARB1 CNTROB ABCB6 TFRC SPTBN4	2.75e-03	144	195	5	C1136382
Disease	Polycystic Ovary Syndrome	ADARB1 CNTROB ABCB6 TFRC SPTBN4	2.75e-03	144	195	5	C0032460
Disease	Cooley's anemia	CACNA1H TFRC	2.75e-03	12	195	2	C0002875
Disease	Thalassemia Intermedia	CACNA1H TFRC	2.75e-03	12	195	2	C0271979
Disease	Thalassemia Minor	CACNA1H TFRC	2.75e-03	12	195	2	C0085578
Disease	Congenital muscular dystrophy	LAMA2 SELENON	2.75e-03	12	195	2	cv:C0699743
Disease	beta Thalassemia	CACNA1H TFRC	2.75e-03	12	195	2	C0005283
Disease	eye color	ARHGAP32 TRANK1 HERC2 CSMD1	3.04e-03	90	195	4	EFO_0003949
Disease	obesity (implicated_via_orthology)	PLXNB2 ADARB1 SDK2 MED13L ANGPTL6 THADA	3.16e-03	215	195	6	DOID:9970 (implicated_via_orthology)
Disease	nevus count, cutaneous melanoma	PLXNB2 TASOR2 HERC2 MED13L	3.16e-03	91	195	4	EFO_0000389, EFO_0004632
Disease	hemolysis	UBL4A ANK1 G6PD	3.72e-03	47	195	3	EFO_0009473
Disease	anti-basement membrane glomerulonephritis (implicated_via_orthology)	SYK CD40LG	3.75e-03	14	195	2	DOID:4780 (implicated_via_orthology)
Disease	iron biomarker measurement, transferrin saturation measurement	TMPRSS6 TFRC	3.75e-03	14	195	2	EFO_0004461, EFO_0006333
Disease	glycodeoxycholate measurement	COL7A1 CSMD1	3.75e-03	14	195	2	EFO_0010493
Disease	transferrin receptor protein 1 measurement	TMPRSS6 TFRC	3.75e-03	14	195	2	EFO_0802142
Disease	anemia (is_implicated_in)	ANK1 G6PD	3.75e-03	14	195	2	DOID:2355 (is_implicated_in)
Disease	prostate cancer (is_marker_for)	EAF2 DAXX AFP DNMT1 TFRC	3.87e-03	156	195	5	DOID:10283 (is_marker_for)
Disease	reticulocyte count	PLXNB2 ZFP36L2 DSTYK WDR20 A4GALT TMEM131L DNMT1 ANK1 TMPRSS6 ABCB6 NARS2 TFRC THADA LRP5 UBASH3B	4.17e-03	1045	195	15	EFO_0007986
Disease	hepatic encephalopathy (biomarker_via_orthology)	GRIA1 G6PD	4.31e-03	15	195	2	DOID:13413 (biomarker_via_orthology)
Disease	Hemoglobin F Disease	CACNA1H TFRC	4.31e-03	15	195	2	C0019025
Disease	platelet component distribution width	ZZEF1 TRANK1 EXOC3L4 A4GALT SYK TMEM131L DLG3 TMPRSS6 LAMA5 ZMAT3 FAR2 SEC14L5	4.61e-03	755	195	12	EFO_0007984
Disease	Bipolar Disorder	ABCA13 ADARB1 TRANK1 STARD9 DLG3 DNMT1 GRIA1 CSMD1 G6PD	4.65e-03	477	195	9	C0005586
Disease	5-oxoproline measurement	RMI1 EXOSC4	4.91e-03	16	195	2	EFO_0010988
Disease	transferrin saturation measurement	TMPRSS6 TFRC	4.91e-03	16	195	2	EFO_0006333
Disease	HbA1c measurement	UBL4A ZFP36L2 A4GALT TMEM131L ANK1 TMPRSS6 NR1H3 TFRC THADA SRGN G6PD	5.49e-03	675	195	11	EFO_0004541
Disease	Van Buchem disease	HSPG2 LRP5	5.54e-03	17	195	2	C0432272
Disease	Chronic Lymphocytic Leukemia	BRAF SYK TFRC	5.79e-03	55	195	3	C0023434
Disease	refractive error	ZZEF1 CNTROB ECEL1 LAMA2 FAR2 BARHL2 GUCY2D	6.16e-03	326	195	7	MONDO_0004892
Disease	Adrenocortical carcinoma	DAXX BRAF	6.20e-03	18	195	2	C0206686

Protein segments in the cluster

Peptide	Gene	Start	Entry
VIAAAARRRDNSHNE	VANGL2	326	Q9ULK5
HSIQVDFNRRADSLQ	ACO1	126	P21399
ALSNSAAIRAEIQRF	AGAP3	26	Q96P47
RVLERSGFHNENSLA	CATSPERG	666	Q6ZRH7
FHSAVAQRLQELARD	EXOC3L4	316	Q17RC7
EDHRNQFGQRDRSSS	BRAF	351	P15056
FVRHLRNDRNTASLE	CDY2A	351	Q9Y6F7
RNHEASQRFDALTLA	DISP3	111	Q9P2K9
AEFLARHSNVNLTIF	APOBEC3D	301	Q96AK3
VSTHLDTRNVAFERN	ANKRD13D	231	Q6ZTN6
AHAFQDTLREAQKAR	ANTXRL	186	A6NF34
ERNRIQLSFHTFALE	CSMD1	66	Q96PZ7
FERILLRAANTHSSA	CD40LG	201	P29965
RTLHNDAASRVAADA	CREB3L3	361	Q68CJ9
NLNRFTEDSLLRHAQ	DNMT1	541	P26358
FEATSRALLAQLHAR	A4GALT	326	Q9NPC4
NEAALIAARHLSDSI	AFG3L2	526	Q9Y4W6
ALHIAARNDDTRTAA	ANK1	176	P16157
THALEQALDFVRASL	GRM2	96	Q14416
SHDRNFLNAIATDII	ABCF3	381	Q9NUQ8
ARTAFTDHQLAQLER	BARHL1	181	Q9BZE3
AHTRNDANRLQDAIA	SPECC1L	631	Q69YQ0
HADAATRQLFQRLTV	ABCA3	226	Q99758
IVFLRNVSHDRDLFS	ABCA13	1331	Q86UQ4
ENATRARAVDSLLNF	ABCB6	446	Q9NP58
LNFRELLREASTEHN	ACSM5	201	Q6NUN0
AATADLDLSHNALQR	AMIGO3	61	Q86WK7
RVDLSNVLDLHAFDS	CBWD5	236	Q5RIA9
HNSNATFDLIARFVS	CC2D2B	1136	Q6DHV5
RQQRAHSLFLASAEF	DAXX	91	Q9UER7
ARLQALSAATAEHAA	RASSF7	191	Q02833
LSAATAEHAARLQAL	RASSF7	196	Q02833
AEHAARLQALDAQAR	RASSF7	201	Q02833
RRHSFFDDNILLNSS	RAD21L1	166	Q9H4I0
AEAAINAFHQSRLRE	RAVER1	106	Q8IY67
NAFHQSRLRERELSV	RAVER1	111	Q8IY67
TNLLSRFTRNEFSHD	RAB25	26	P57735
QLVDLSRRFLVHDSF	HSPG2	581	P98160
DRLSNHISSLFREDQ	G6PD	181	P11413
DQSSRHAAELRDFKN	OLFML3	46	Q9NRN5
DHEQLRAFALTLQAR	PCDHGB6	521	Q9Y5F9
DFAHRLSAFQRVDTL	LGALS4	296	P56470
SREARQQRFAHFTEL	NR1H3	246	Q13133
DTAHLLRAFDQASSR	ANKRD34B	301	A5PLL1
EADRFSDSHNALRIL	NUP210	166	Q8TEM1
SQRDREEALHQFRSG	DDX3X	476	O00571
RFDDTLRHAVQLNVT	FAR2	116	Q96K12
RNFRLSEHRQALAAA	OTUD1	191	Q5VV17
AAAQAARDVHTLLDR	EXOSC4	216	Q9NPD3
FQHSRSQGERLLSRE	MED13L	2071	Q71F56
EQRTQARAAARAHTA	MAGEB18	311	Q96M61
ANSSQLRRAHDAVLT	GUCY2D	296	Q02846
NLANRSHAELETALR	GPC1	76	P35052
IDEQEANASTFHRSR	HERC2	971	O95714
VLEDFRSAAAQQLHL	IMPG1	656	Q17R60
EESNFVHRDLAARNV	SYK	486	P43405
RLDASTSHQNLRVDD	FSD1	271	Q9BTV5
EAANLSHAAAQRIVR	HMX3	291	A6NHT5
LDNNCARLTLHFNRD	JAG2	966	Q9Y219
FLRDALSISNAHTVD	METTL25	26	Q8N6Q8
FLDAAIASRRSHQQD	KIF26B	656	Q2KJY2
ASNDHDAAINRYSRL	APPL1	136	Q9UKG1
LSFIHRANLDGSFRQ	LRP5	216	O75197
IANSRTAHARAKADA	JPH1	376	Q9HDC5
RVDLSNVLDLHAFDS	CBWD2	236	Q8IUF1
RVDLSNVLDLHAFDS	CBWD1	236	Q9BRT8
NFIHTLENQREFSAR	PLXNB2	1331	O15031
FNVTHDLARALAEQL	GGT7	266	Q9UJ14
LNQAADDHALRTIVF	PDE1B	171	Q01064
ERDRATASHLSQALQ	EVPL	801	Q92817
SDSLRNLNKERQFHF	FAM83D	521	Q9H4H8
RLSSHDLQFQLVEAF	NRDE2	626	Q9H7Z3
LHNNSLRALEAGAFR	LRRC24	81	Q50LG9
RHLAIASLEDQNFRR	LINGO3	206	P0C6S8
FNANHALSGLERDRL	LAMB2	1291	P55268
AACHSFRAAENRELN	GOLGA6L4	556	A6NEF3
HQINSTRDFESIRLA	TUBGCP4	546	Q9UGJ1
ARINHADFATVQLRN	LAMA2	2806	P24043
RLANFSRGHNLSRDE	KCNK13	56	Q9HB14
TLCNINRFRHSALSD	ASIC4	116	Q96FT7
RQVAEARSRQAHSAL	ARMC7	171	Q9H6L4
QSRSLAALFDSLRHV	FAM181B	161	A6NEQ2
ASVRLTAEQARFFLH	LAMA5	1171	O15230
RDNATLQATLHAARD	LAMA5	2421	O15230
AVLFSADLRQSRHAQ	OGG1	316	O15527
LDNLNVRETHSLFFR	DDOST	51	P39656
ARAAQSALAAIFNLH	ADARB1	286	P78563
VASNIQRLRHEFDSE	ARHGAP32	411	A7KAX9
TRLNSSHEAFAASLR	DSTYK	591	Q6XUX3
ARAARFLAANLDASI	ECEL1	106	O95672
QFTDALVTIRNRHND	PDK2	111	Q15119
ISNRHEFGRLLSTAN	PLOD2	506	O00469
DLRDSRQQAAQAFIH	NOL7	181	Q9UMY1
RLISDFQRHSISDDD	PRICKLE3	71	O43900
EVAEFLARHSNVNLT	APOBEC3F	286	Q8IUX4
HFIQALDSLSRSNLD	CDC45	396	O75419
AAHAASRSQAEDVRV	IDH3B	31	O43837
STLRQADFEAHNILR	GMPS	586	P49915
ATAFRLDTAQRSHLL	DOK1	86	Q99704
DIDASHNRFRDNSGL	EAF2	226	Q96CJ1
SNAFQDRLGASQERH	ELOA	241	Q14241
NAFASDRISLHRDLG	GALNT3	151	Q14435
RDSQHLSTFNLERTA	FRMPD4	1071	Q14CM0
AHRSQTRDEFAQLFQ	ATG9A	456	Q7Z3C6
SSRHQEEAARARAEA	CEP250	1951	Q9BV73
SSFRQHQESLAAERE	FHOD3	446	Q2V2M9
RVDLSNVLDLHAFDS	CBWD3	236	Q5JTY5
RVDLSNVLDLHAFDS	CBWD6	236	Q4V339
ASAEAQRAAARFHQL	ANGPTL6	146	Q8NI99
RNATHEQAAAALKRA	DLG3	441	Q92796
RTAFSDHQLNQLERS	BARHL2	236	Q9NY43
SIEAFRQRLNQISHD	ALOX12B	661	O75342
VRTANILEFAANHAS	GPR142	231	Q7Z601
TDVNFALELSDLRHR	MARF1	451	Q9Y4F3
ELLDAHFQARDTTTR	ITIH6	571	Q6UXX5
ESAAALAAAATRHLQ	IPO9	416	Q96P70
RSSDAFTTQHALRQA	KIF4A	506	O95239
RLQAEAEEARSRAHA	LAMB3	961	Q13751
ATQDNAHRAEATRRV	COL7A1	1061	Q02388
ELFARRLASHLNNVF	EXOC1	341	Q9NV70
SQEHAAFRFALSQLT	GRIA1	36	P42261
QRARHLSNDSTLASF	CACNA1H	436	O95180
EFNAHDLSSVARREV	DHX40	701	Q8IX18
RTLLIEAHNETFANR	SEC14L5	91	O43304
ALHQIRAARAQDDVS	SDK2	11	Q58EX2
NLSRSIDAALFREHL	PRRT3	811	Q5FWE3
AASRERQEEQSAAIH	EPB41L3	921	Q9Y2J2
NLNFENLRETLRTFH	HELB	156	Q8NG08
NERLLDRQAAAFTAS	MED11	41	Q9P086
AQESSLRQAASLREH	CNTROB	466	Q8N137
FLLNFTESRTLHRNE	AFP	11	P02771
SLSELFRSQAHRDFV	WDR77	286	Q9BQA1
SHFLASATAAARAQR	nan	356	A6NNC1
HFLASATAAARAQRS	nan	631	A6NNC1
NAVDTNLLFRTFEHL	MROH5	1276	Q6ZUA9
ASIAAELQFRSLSRH	MAP3K4	1236	Q9Y6R4
ALSNAAHLDVQRRSG	PUSL1	71	Q8N0Z8
RLRNFLTDSDSQHSH	TAF5L	76	O75529
SQRDGHFLQESRRLS	SYNC	311	Q9H7C4
HFLQESRRLSAQFEN	SYNC	316	Q9H7C4
HNRIARATEALQTFR	TRIM46	386	Q7Z4K8
FSAEEVFHRELRSNS	TMEM43	291	Q9BTV4
HRFTSRLQEELNTTD	THADA	116	Q6YHU6
RFQENSSDHSETRLL	TMEM71	216	Q6P5X7
LRAFESDVFHNRTTN	TRAFD1	186	O14545
LHRNFTETRNNIARD	TBC1D21	111	Q8IYX1
IQDIRHFSQRDALSL	TMEM131L	316	A2VDJ0
FDLTNSSQRFIQRHD	TC2N	176	Q8N9U0
RHLLFSDVAAQQSLR	LRRC41	201	Q15345
FNRNADRSIERFSHN	RMI1	341	Q9H9A7
TFRAENSQSRRHLAE	NARS2	241	Q96I59
SRNLRAAHALEHTFA	PTCH2	1046	Q9Y6C5
AFADRSNLRAHLQTH	SNAI2	221	O43623
NTHRQAARVNLSFDF	PLXDC2	151	Q6UX71
VQRASFFAASDENHR	SIPA1L1	1691	O43166
EQRAHVQEFFASSRD	SETD4	161	Q9NVD3
FNEVSRAREAVLDAH	NSMCE4A	121	Q9NXX6
RHAIAASFFTAQEAR	OCSTAMP	426	Q9BR26
RAQDLHAERSAAQLS	PTGES2	81	Q9H7Z7
NSFRAVLDVANHFSR	PEX13	156	Q92968
DLLHFGRDRANSTQS	WDR20	336	Q8TBZ3
TATLEQARHNNRFRE	PNKP	451	Q96T60
LRDHNRLDSQAKFVA	STARD9	3181	Q9P2P6
AAVSDDQDLLHSSRF	PIAS1	566	O75925
ERAQEQHSVFLATDR	RSPO2	226	Q6UXX9
TRFSLARQVDGDNSH	TFRC	21	P02786
RVHFLENSSRALAFL	SPTBN5	111	Q9NRC6
DFVDRTRSSHQLQAL	SNED1	956	Q8TER0
FADRSNLRAHLQTHS	SNAI3	246	Q3KNW1
VDRFLNSSNDHRFQA	ASCC3	291	Q8N3C0
HELSSRVSFQEARLA	CHODL	46	Q9H9P2
ARNSEVRSNAALLFV	NCAPG2	341	Q86XI2
NRQAATAELRRSLAH	CLCF1	121	Q9UBD9
DEAFSFKSNLQRHRR	ZNF845	641	Q96IR2
AARLAEHERVAASTQ	RNF214	601	Q8ND24
AFADRSNLRAHLQTH	SNAI1	216	O95863
EVAHRDFANSFSILR	TMPRSS13	276	Q9BYE2
LEAASSHAEAARQLL	TSNARE1	461	Q96NA8
ERQELFASRFLHSSI	SPEN	1521	Q96T58
LFLSVHDAVQTARAR	SLC26A1	676	Q9H2B4
RAVASINQHLLRSDD	RYR3	726	Q15413
RRSHTEAALAFEQEL	SH2D3A	436	Q9BRG2
QLQDVFLLSSRDHRT	SEMA3B	306	Q13214
DVSLSNRLALHNSRF	TUT1	381	Q9H6E5
SDAFHDNLRSLDRNL	SRGN	126	P10124
FETDSRRFLNHLNNR	SYCP2L	271	Q5T4T6
RHAEAQAAARQELAL	SELENON	51	Q9NZV5
TADALRFHSQVRDLL	SPTBN4	1941	Q9H254
RALHSQASAISQDRE	ZNF229	11	Q9UJW7
RHLEAAALLSERNAD	TRMT6	356	Q9UJA5
FLSARLAQQREAERH	ZDHHC5	501	Q9C0B5
HFSAADASRVLEQLQ	UBL4A	106	P11441
RSSKDLRARVDFHNN	WNT9A	186	O14904
HRALTELFFVTENRA	ZZEF1	2896	O43149
HAKRLRLAEAQSNSF	ZMAT3	171	Q9HA38
DEAERLTRLNHLSFA	TRAPPC8	26	Q9Y2L5
NEISRAHAAEVSFRD	TASOR2	856	Q5VWN6
SRTFFSENGLREHLQ	ZNF423	936	Q2M1K9
IFSRDIRFANHETLQ	UBASH3B	246	Q8TF42
AARLNVARDSDIEHT	TRANK1	1951	O15050
DRSFSENGDRSQHLL	ZFP36L2	121	P47974
LSNNRFVHKDLAARN	PTK7	921	Q13308
SRDFQRRTLLQDLHA	ZYG11A	636	Q6WRX3
RANVELDHATLVRFS	TBL2	131	Q9Y4P3
LSSRNFIHRDLAARN	TYRO3	646	Q06418
SQEFVAAHRALLESR	WDR81	521	Q562E7
NRHFSQDLTRRESSA	TMPRSS6	96	Q8IU80
SERLSIRDLLNHAFF	WNK3	391	Q9BYP7
SLSDSLFVLHVQRAD	MYO1C	971	O00159