Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.58e-0735725GO:0015020
GeneOntologyMolecularFunctionglycosaminoglycan binding

SELL THBS1 FBN1 ADAMTS3 EGFLAM LTBP2 TNXB STAB1

5.40e-06268728GO:0005539
GeneOntologyMolecularFunctionphorbol ester receptor activity

UNC13B UNC13C

1.28e-052722GO:0001565
GeneOntologyMolecularFunctionnon-kinase phorbol ester receptor activity

UNC13B UNC13C

1.28e-052722GO:0001566
GeneOntologyMolecularFunctioncalcium ion binding

UNC13B SELL CLEC4E THBS1 FBN1 UNC13C EGFLAM LTBP2 FER1L5 CRB1 PROS1 STAB1

1.38e-057497212GO:0005509
GeneOntologyMolecularFunctiondiacylglycerol binding

UNC13B DGKD UNC13C

2.43e-0516723GO:0019992
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

SCARF1 THBS1 STAB1

3.53e-0518723GO:0030169
GeneOntologyMolecularFunctionheparin binding

SELL THBS1 FBN1 ADAMTS3 LTBP2 TNXB

6.74e-05192726GO:0008201
GeneOntologyMolecularFunctionscavenger receptor activity

SCARF1 MEGF10 STAB1

1.24e-0427723GO:0005044
GeneOntologyMolecularFunctionretinoic acid binding

UGT2B4 UGT2B15 UGT2B17

1.38e-0428723GO:0001972
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.29e-04153725GO:0008194
GeneOntologyMolecularFunctionlipoprotein particle binding

SCARF1 THBS1 STAB1

2.71e-0435723GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

SCARF1 THBS1 STAB1

2.71e-0435723GO:0071814
GeneOntologyMolecularFunctionextracellular matrix structural constituent

THBS1 FBN1 LTBP2 MUC4 TNXB

5.89e-04188725GO:0005201
GeneOntologyMolecularFunctionretinoid binding

UGT2B4 UGT2B15 UGT2B17

6.92e-0448723GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

UGT2B4 UGT2B15 UGT2B17

7.35e-0449723GO:0019840
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

9.90e-04211725GO:0016758
GeneOntologyMolecularFunctionsulfur compound binding

SELL THBS1 FBN1 ADAMTS3 LTBP2 TNXB

1.09e-03323726GO:1901681
GeneOntologyMolecularFunctionC2H2 zinc finger domain binding

ZXDA ZXDB

1.68e-0317722GO:0070742
GeneOntologyMolecularFunctionextracellular matrix binding

THBS1 LTBP2 TNXB

2.33e-0373723GO:0050840
GeneOntologyMolecularFunctionRNA stem-loop binding

RC3H2 RC3H1

2.58e-0321722GO:0035613
GeneOntologyMolecularFunctionlipid binding

UNC13B SELL CLEC4E THBS1 UGT2B4 UGT2B15 UGT2B17 DGKD UNC13C DENND1A

2.77e-039887210GO:0008289
GeneOntologyMolecularFunctiondouble-stranded RNA binding

RC3H2 RC3H1 HSP90AB1

2.82e-0378723GO:0003725
GeneOntologyMolecularFunctionsyntaxin-1 binding

UNC13B UNC13C

3.36e-0324722GO:0017075
GeneOntologyMolecularFunctioncargo receptor activity

SCARF1 MEGF10 STAB1

3.59e-0385723GO:0038024
GeneOntologyMolecularFunctionglycosyltransferase activity

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.84e-03288725GO:0016757
GeneOntologyMolecularFunctionpolysaccharide binding

CLEC18A CLEC18C

5.57e-0331722GO:0030247
GeneOntologyMolecularFunctioncell adhesion molecule binding

SELL THBS1 BMPR2 FBN1 TENM3 TNXB HSP90AB1

5.77e-03599727GO:0050839
GeneOntologyMolecularFunctionmonocarboxylic acid binding

UGT2B4 UGT2B15 UGT2B17

6.82e-03107723GO:0033293
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

RC3H2 RC3H1 NEURL1 SIAH1 SIAH2 OBI1

7.16e-03473726GO:0004842
GeneOntologyMolecularFunctionubiquitin conjugating enzyme binding

SIAH1 SIAH2

7.46e-0336722GO:0031624
GeneOntologyBiologicalProcessbiphenyl catabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.16e-118705GO:0070980
GeneOntologyBiologicalProcessbiphenyl metabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

9.68e-1110705GO:0018879
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.03e-1012705GO:0052697
GeneOntologyBiologicalProcesscellular glucuronidation

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

7.59e-0921705GO:0052695
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.42e-0826705GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.42e-0826705GO:0006063
GeneOntologyBiologicalProcessbenzene-containing compound metabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.56e-0737705GO:0042537
GeneOntologyBiologicalProcessxenobiotic catabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.56e-0737705GO:0042178
GeneOntologyBiologicalProcessandrogen metabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.79e-0738705GO:0008209
GeneOntologyBiologicalProcessestrogen metabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

8.94e-0752705GO:0008210
GeneOntologyBiologicalProcessendocytosis

SCARF1 THBS1 LRP3 DGKD ARHGAP27 TAFA4 FER1L5 DENND1A MEGF10 PROS1 PEAR1 STAB1

1.99e-058277012GO:0006897
GeneOntologyBiologicalProcessnegative regulation of T-helper cell differentiation

RC3H2 RC3H1 HLX

5.50e-0522703GO:0045623
GeneOntologyBiologicalProcessheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

SCARF1 SELL TENM3 CRB1

6.23e-0563704GO:0007157
GeneOntologyBiologicalProcessdense core granule priming

UNC13B UNC13C

6.78e-054702GO:0061789
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell differentiation

RC3H2 RC3H1 HLX

9.20e-0526703GO:0043371
GeneOntologyBiologicalProcessxenobiotic metabolic process

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.18e-04141705GO:0006805
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell differentiation

RC3H2 RC3H1 HLX

1.57e-0431703GO:0046639
GeneOntologyBiologicalProcessnegative regulation of synaptic plasticity

UNC13B UNC13C

1.69e-046702GO:0031914
GeneOntologyBiologicalProcessT follicular helper cell differentiation

RC3H2 RC3H1

2.36e-047702GO:0061470
GeneOntologyBiologicalProcessrecognition of apoptotic cell

MEGF10 PEAR1

2.36e-047702GO:0043654
GeneOntologyBiologicalProcessimport into cell

SCARF1 THBS1 LRP3 DGKD ARHGAP27 TAFA4 FER1L5 DENND1A MEGF10 PROS1 PEAR1 STAB1

2.42e-0410747012GO:0098657
GeneOntologyBiologicalProcesscell-cell adhesion

SCARF1 SELL RC3H2 THBS1 TENM3 RC3H1 HLX MUC4 TNXB MEGF10 CRB1 PEAR1

2.48e-0410777012GO:0098609
GeneOntologyBiologicalProcessphagocytosis

THBS1 TAFA4 FER1L5 MEGF10 PROS1 PEAR1

3.35e-04274706GO:0006909
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell activation

RC3H2 RC3H1 HLX

3.38e-0440703GO:2000515
GeneOntologyBiologicalProcesspositive regulation of vascular endothelial growth factor signaling pathway

ADAMTS3 TNXB

4.02e-049702GO:1900748
GeneOntologyBiologicalProcessT cell differentiation involved in immune response

CLEC4E RC3H2 RC3H1 HLX

4.18e-04103704GO:0002292
GeneOntologyBiologicalProcesspresynaptic dense core vesicle exocytosis

UNC13B UNC13C

5.02e-0410702GO:0099525
GeneOntologyBiologicalProcessapoptotic cell clearance

THBS1 MEGF10 PEAR1

5.80e-0448703GO:0043277
GeneOntologyBiologicalProcessneuronal dense core vesicle exocytosis

UNC13B UNC13C

7.33e-0412702GO:0099011
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell activation

RC3H2 RC3H1 HLX

7.34e-0452703GO:0046636
GeneOntologyBiologicalProcessspleen development

RC3H2 RC3H1 NKX3-2

7.34e-0452703GO:0048536
GeneOntologyBiologicalProcesscellular response to xenobiotic stimulus

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

9.47e-04222705GO:0071466
GeneOntologyBiologicalProcessregulation of T-helper cell differentiation

RC3H2 RC3H1 HLX

9.61e-0457703GO:0045622
GeneOntologyBiologicalProcessnegative regulation of T-helper 17 cell differentiation

RC3H2 RC3H1

1.01e-0314702GO:2000320
GeneOntologyBiologicalProcessnegative regulation of T cell differentiation

RC3H2 RC3H1 HLX

1.01e-0358703GO:0045581
GeneOntologyCellularComponentnuclear outer membrane

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.52e-0740725GO:0005640
GeneOntologyCellularComponentcollagen-containing extracellular matrix

ADAMTS10 THBS1 ADAMTSL1 FBN1 ADAMTS3 ADAMTS20 EGFLAM LTBP2 MUC4 TNXB

1.32e-055307210GO:0062023
GeneOntologyCellularComponentextracellular matrix

ADAMTS10 THBS1 ADAMTSL1 FBN1 ADAMTS3 ADAMTS20 EGFLAM LTBP2 MUC4 TNXB

8.03e-056567210GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTS10 THBS1 ADAMTSL1 FBN1 ADAMTS3 ADAMTS20 EGFLAM LTBP2 MUC4 TNXB

8.23e-056587210GO:0030312
GeneOntologyCellularComponentphagocytic cup

CLEC4E MEGF10 PEAR1

1.64e-0431723GO:0001891
GeneOntologyCellularComponentpresynaptic membrane

UNC13B TENM3 CNTNAP4 UNC13C GRM2 DENND1A

3.85e-04277726GO:0042734
GeneOntologyCellularComponentmicrofibril

ADAMTS10 FBN1

8.90e-0413722GO:0001527
GeneOntologyCellularComponentpresynaptic active zone

UNC13B TENM3 UNC13C EGFLAM

1.43e-03141724GO:0048786
GeneOntologyCellularComponentclathrin-coated pit

BMPR2 LRP3 DGKD

2.66e-0380723GO:0005905
GeneOntologyCellularComponentorganelle outer membrane

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.76e-03279725GO:0031968
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

UNC13B UNC13C

2.82e-0323722GO:0098831
GeneOntologyCellularComponentouter membrane

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.84e-03281725GO:0019867
GeneOntologyCellularComponentpresynapse

UNC13B TENM3 CNTNAP4 UNC13C EGFLAM TAFA4 GRM2 FER1L5 DENND1A

3.30e-03886729GO:0098793
GeneOntologyCellularComponentexocytic vesicle membrane

UNC13B UNC13C TAFA4 FER1L5

3.40e-03179724GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

UNC13B UNC13C TAFA4 FER1L5

3.40e-03179724GO:0030672
HumanPhenoMicrospherophakia

ADAMTS10 FBN1 LTBP2

2.07e-074203HP:0030961
HumanPhenoSpherophakia

ADAMTS10 FBN1 LTBP2

5.15e-075203HP:0034375
HumanPhenoAplasia/Hypoplasia of the lens

ADAMTS10 FBN1 LTBP2

2.29e-0515203HP:0008063
HumanPhenoAbnormality of lens shape

ADAMTS10 FBN1 LTBP2

4.07e-0518203HP:0011526
HumanPhenoShallow anterior chamber

ADAMTS10 FBN1 LTBP2

4.07e-0518203HP:0000594
HumanPhenoBroad skull

ADAMTS10 FBN1

4.38e-053202HP:0002682
HumanPhenoIridodonesis

FBN1 LTBP2

1.45e-045202HP:0100693
HumanPhenoPrimary congenital glaucoma

ADAMTSL1 LTBP2

2.18e-046202HP:0008007
MousePhenoabnormal cilary zonule morphology

ADAMTS10 LTBP2

1.58e-052562MP:0014176
DomainEGF_3

SCARF1 SELL CLEC18A THBS1 MUC3B FBN1 TENM3 CNTNAP4 CLEC18C EGFLAM LTBP2 MUC4 TNXB VWDE MEGF10 CRB1 PROS1 PEAR1 STAB1

2.46e-202357219PS50026
DomainEGF

SCARF1 SELL CLEC18A THBS1 MUC3B FBN1 TENM3 CNTNAP4 CLEC18C EGFLAM LTBP2 MUC4 TNXB VWDE MEGF10 CRB1 PROS1 PEAR1 STAB1

2.46e-202357219SM00181
DomainEGF-like_dom

SCARF1 SELL CLEC18A THBS1 MUC3B FBN1 TENM3 CNTNAP4 CLEC18C EGFLAM LTBP2 MUC4 TNXB VWDE MEGF10 CRB1 PROS1 PEAR1 STAB1

7.42e-202497219IPR000742
DomainEGF_1

SCARF1 SELL CLEC18A THBS1 MUC3B FBN1 TENM3 CNTNAP4 CLEC18C EGFLAM LTBP2 MUC4 TNXB VWDE MEGF10 CRB1 PROS1 PEAR1 STAB1

1.17e-192557219PS00022
DomainEGF-like_CS

SCARF1 SELL CLEC18A THBS1 MUC3B FBN1 TENM3 CNTNAP4 CLEC18C EGFLAM LTBP2 MUC4 TNXB VWDE MEGF10 CRB1 PROS1 PEAR1 STAB1

1.82e-192617219IPR013032
DomainEGF_2

SCARF1 SELL CLEC18A THBS1 MUC3B FBN1 TENM3 CNTNAP4 CLEC18C EGFLAM LTBP2 MUC4 TNXB VWDE MEGF10 CRB1 PROS1 PEAR1 STAB1

2.42e-192657219PS01186
DomainEGF

SELL CNTNAP4 EGFLAM LTBP2 MUC4 TNXB CRB1 PROS1 STAB1

1.29e-09126729PF00008
DomainUDPGT

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.43e-0821725PF00201
DomainUDPGT

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.43e-0821725PS00375
DomainUDP_glucos_trans

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.43e-0821725IPR002213
DomainEGF_extracell

SCARF1 TENM3 LTBP2 TNXB MEGF10 STAB1

1.13e-0760726IPR013111
DomainEGF_2

SCARF1 TENM3 LTBP2 TNXB MEGF10 STAB1

1.13e-0760726PF07974
DomainTSP_1

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20

1.52e-0763726PF00090
DomainTSP1

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20

1.83e-0765726SM00209
DomainTSP1_rpt

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20

1.83e-0765726IPR000884
DomainTSP1

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20

1.83e-0765726PS50092
DomainEGF_CA

THBS1 FBN1 EGFLAM LTBP2 CRB1 PROS1 STAB1

4.42e-07122727SM00179
DomainEGF-like_Ca-bd_dom

THBS1 FBN1 EGFLAM LTBP2 CRB1 PROS1 STAB1

4.94e-07124727IPR001881
DomainPeptidase_M12B_ADAM-TS

ADAMTS10 ADAMTSL1 ADAMTS3 ADAMTS20

2.03e-0624724IPR013273
DomainGrowth_fac_rcpt_

SCARF1 FBN1 LTBP2 TNXB CRB1 PROS1 STAB1

2.32e-06156727IPR009030
DomainLaminin_G

THBS1 CNTNAP4 EGFLAM CRB1 PROS1

2.89e-0658725IPR001791
DomainLaminin_EGF

SCARF1 MEGF10 PEAR1 STAB1

9.71e-0635724PF00053
DomainLAM_G_DOMAIN

CNTNAP4 EGFLAM CRB1 PROS1

1.36e-0538724PS50025
DomainLaminin_EGF

SCARF1 MEGF10 PEAR1 STAB1

1.36e-0538724IPR002049
DomainLaminin_G_2

CNTNAP4 EGFLAM CRB1 PROS1

1.67e-0540724PF02210
Domain-

GLIPR1 CLEC18A CLEC18C

2.42e-05157233.40.33.10
DomainCAP

GLIPR1 CLEC18A CLEC18C

2.42e-0515723PF00188
DomainCAP_domain

GLIPR1 CLEC18A CLEC18C

2.42e-0515723IPR014044
DomainSCP

GLIPR1 CLEC18A CLEC18C

2.42e-0515723SM00198
DomainAllrgn_V5/Tpx1

GLIPR1 CLEC18A CLEC18C

2.42e-0515723IPR001283
DomainLamG

CNTNAP4 EGFLAM CRB1 PROS1

2.45e-0544724SM00282
Domain-

THBS1 CNTNAP4 EGFLAM CRB1 PROS1

3.27e-05957252.60.120.200
Domain-

SELL CLEC18A CLEC4E CLEC18C STAB1

3.62e-05977253.10.100.10
DomainC-type_lectin-like/link

SELL CLEC18A CLEC4E CLEC18C STAB1

3.99e-0599725IPR016186
Domain7-in-absentia-prot_TRAF-dom

SIAH1 SIAH2

4.39e-053722IPR018121
DomainUnc-13

UNC13B UNC13C

4.39e-053722IPR027080
DomainSina

SIAH1 SIAH2

4.39e-053722PF03145
DomainPLAC

ADAMTS10 ADAMTSL1 ADAMTS3

5.09e-0519723PS50900
DomainPLAC

ADAMTS10 ADAMTSL1 ADAMTS3

5.09e-0519723IPR010909
DomainCTDL_fold

SELL CLEC18A CLEC4E CLEC18C STAB1

5.79e-05107725IPR016187
DomainSINA-like

SIAH1 SIAH2

8.75e-054722IPR004162
DomainZnf_SIAH

SIAH1 SIAH2

8.75e-054722IPR013010
DomainADAM_spacer1

ADAMTS10 ADAMTS3 ADAMTS20

9.20e-0523723IPR010294
DomainADAM_spacer1

ADAMTS10 ADAMTS3 ADAMTS20

9.20e-0523723PF05986
DomainMunc13_dom-2

UNC13B UNC13C

1.45e-045722IPR014772
DomainMembr_traf_MHD

UNC13B UNC13C

1.45e-045722PF10540
DomainZF_SIAH

SIAH1 SIAH2

1.45e-045722PS51081
DomainMHD2

UNC13B UNC13C

1.45e-045722PS51259
DomainMunc13_subgr_dom-2

UNC13B UNC13C

1.45e-045722IPR019558
DomainDUF1041

UNC13B UNC13C

1.45e-045722SM01145
DomainC_TYPE_LECTIN_1

SELL CLEC18A CLEC4E CLEC18C

2.57e-0480724PS00615
DomainDUF1041

UNC13B UNC13C

3.04e-047722PF06292
DomainMunc13_1

UNC13B UNC13C

3.04e-047722IPR014770
DomainCAPS_dom

UNC13B UNC13C

3.04e-047722IPR010439
DomainMHD1

UNC13B UNC13C

3.04e-047722PS51258
DomainTB

FBN1 LTBP2

3.04e-047722PF00683
DomainLectin_C

SELL CLEC18A CLEC4E CLEC18C

3.10e-0484724PF00059
DomainCLECT

SELL CLEC18A CLEC4E CLEC18C

3.10e-0484724SM00034
DomainC_TYPE_LECTIN_2

SELL CLEC18A CLEC4E CLEC18C

3.25e-0485724PS50041
DomainEGF_Lam

MEGF10 PEAR1 STAB1

3.29e-0435723SM00180
DomainC-type_lectin-like

SELL CLEC18A CLEC4E CLEC18C

3.40e-0486724IPR001304
DomainEGF_CA

THBS1 FBN1 LTBP2 PROS1

3.40e-0486724PF07645
Domain-

FBN1 LTBP2

4.04e-0487223.90.290.10
DomainPeptidase_M12B_N

ADAMTS10 ADAMTS3 ADAMTS20

4.54e-0439723IPR002870
DomainPep_M12B_propep

ADAMTS10 ADAMTS3 ADAMTS20

4.54e-0439723PF01562
DomainDISINTEGRIN_1

ADAMTS10 ADAMTS3 ADAMTS20

4.90e-0440723PS00427
DomainReprolysin

ADAMTS10 ADAMTS3 ADAMTS20

4.90e-0440723PF01421
DomainADAM_MEPRO

ADAMTS10 ADAMTS3 ADAMTS20

4.90e-0440723PS50215
DomainDISINTEGRIN_2

ADAMTS10 ADAMTS3 ADAMTS20

4.90e-0440723PS50214
DomainPeptidase_M12B

ADAMTS10 ADAMTS3 ADAMTS20

4.90e-0440723IPR001590
DomainTB

FBN1 LTBP2

5.18e-049722PS51364
DomainTB_dom

FBN1 LTBP2

5.18e-049722IPR017878
DomainDisintegrin_dom

ADAMTS10 ADAMTS3 ADAMTS20

5.27e-0441723IPR001762
DomainEGF_Ca-bd_CS

FBN1 LTBP2 CRB1 PROS1

5.37e-0497724IPR018097
DomainEGF_CA

FBN1 LTBP2 CRB1 PROS1

5.80e-0499724PS01187
DomainASX_HYDROXYL

FBN1 LTBP2 CRB1 PROS1

6.02e-04100724PS00010
DomainC-type_lectin_CS

SELL CLEC18A CLEC18C

6.07e-0443723IPR018378
DomainEGF-type_Asp/Asn_hydroxyl_site

FBN1 LTBP2 CRB1 PROS1

7.50e-04106724IPR000152
DomainLaminin_G_1

EGFLAM PROS1

7.88e-0411722PF00054
DomainZF_RING_1

RC3H2 RC3H1 NEURL1 SIAH1 SIAH2 OBI1

8.97e-04291726PS00518
DomainZF_RING_2

RC3H2 RC3H1 NEURL1 SIAH1 SIAH2 OBI1

1.01e-03298726PS50089
DomainRING

RC3H2 RC3H1 NEURL1 SIAH1 SIAH2 OBI1

1.14e-03305726SM00184
DomainPLAC

ADAMTS10 ADAMTSL1

1.29e-0314722PF08686
Domain-

SIAH1 SIAH2

1.29e-03147223.90.890.10
Domain-

SIAH1 SIAH2

1.29e-03147222.60.210.10
DomainC1_1

UNC13B DGKD UNC13C

1.38e-0357723PF00130
DomainConA-like_dom

THBS1 CNTNAP4 EGFLAM CRB1 PROS1

1.57e-03219725IPR013320
DomainZnf_RING

RC3H2 RC3H1 NEURL1 SIAH1 SIAH2 OBI1

1.60e-03326726IPR001841
DomainSIAH-type

SIAH1 SIAH2

1.70e-0316722IPR013323
DomainVWD

MUC4 VWDE

1.70e-0316722SM00216
DomainEMI_domain

MEGF10 PEAR1

1.70e-0316722IPR011489
DomainVWF_type-D

MUC4 VWDE

1.70e-0316722IPR001846
DomainVWFD

MUC4 VWDE

1.70e-0316722PS51233
DomainVWD

MUC4 VWDE

1.70e-0316722PF00094
DomainEMI

MEGF10 PEAR1

1.92e-0317722PS51041
DomainZF_DAG_PE_1

UNC13B DGKD UNC13C

1.93e-0364723PS00479
DomainZF_DAG_PE_2

UNC13B DGKD UNC13C

1.93e-0364723PS50081
DomainC1

UNC13B DGKD UNC13C

2.02e-0365723SM00109
DomainPE/DAG-bd

UNC13B DGKD UNC13C

2.11e-0366723IPR002219
DomainMetalloPept_cat_dom

ADAMTS10 ADAMTS3 ADAMTS20

3.78e-0381723IPR024079
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20 MUC4

3.75e-0968507M27303
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20

4.36e-0939506M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20

4.36e-0939506MM15165
PathwayREACTOME_PREDNISONE_ADME

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.47e-0823505MM16639
PathwayREACTOME_GLUCURONIDATION

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.85e-0824505MM14599
PathwayREACTOME_GLUCURONIDATION

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.30e-0825505M17787
PathwayWP_GLUCURONIDATION

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.30e-0825505MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.30e-0825505M605
PathwayWP_GLUCURONIDATION

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.84e-0826505M39404
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

4.22e-0828505M19580
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20 MUC4

1.03e-07109507MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20 MUC4

1.17e-07111507M27416
PathwayREACTOME_PARACETAMOL_ADME

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.40e-0739505MM15695
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.11e-0741505M7399
PathwayREACTOME_ASPIRIN_ADME

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

4.47e-0744505M45014
PathwayREACTOME_ASPIRIN_ADME

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

5.02e-0745505MM15694
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20 MUC4

6.62e-07143507M27275
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

9.50e-0751505M17726
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.05e-0652505M14171
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.39e-0655505M14933
PathwayKEGG_RETINOL_METABOLISM

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.98e-0664505M9488
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

4.65e-0670505M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

5.35e-0672505M9257
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20 MUC4

2.64e-05250507M27554
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.70e-05107505MM14595
PathwayREACTOME_DRUG_ADME

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

4.05e-05109505M45012
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

4.05e-05109505M18788
PathwayREACTOME_DRUG_ADME

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

6.16e-05119505MM15692
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11 HSP90AB1

1.18e-04219506MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11 HSP90AB1

1.21e-04220506M10320
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

4.61e-04183505M39588
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

ADAMTS10 THBS1 FBN1

1.19e-0359503M39886
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

THBS1 FBN1 ADAMTS3 LTBP2 TNXB

2.14e-03258505MM14572
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

ADAMTS10 THBS1 ADAMTSL1 FBN1 THSD7A ADAMTS3 ADAMTS20 SIAH2 PIGG MUC4 LYPD8 PROS1

2.80e-0313895012MM15307
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FBN1 LTBP2

3.51e-0325502M39713
PathwayREACTOME_DECTIN_2_FAMILY

CLEC4E MUC4

3.79e-0326502M27483
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

THBS1 FBN1 ADAMTS3 LTBP2 TNXB

4.09e-03300505M610
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

7.42e-13773526074487
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.97e-12873532093886
Pubmed

Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.

UGT2B15 UGT2B17 UGT2B28

8.87e-09373319572376
Pubmed

Genetic variations in UGT2B28, UGT2B17, UGT2B15 genes and the risk of prostate cancer: A case-control study.

UGT2B15 UGT2B17 UGT2B28

8.87e-09373328882566
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS10 THBS1 ADAMTSL1 THSD7A ADAMTS3 ADAMTS20

1.24e-087573620637190
Pubmed

Weill-Marchesani Syndrome

ADAMTS10 FBN1 LTBP2

3.54e-08473320301293
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT2B4 UGT2B15 UGT2B17

4.93e-07873318719240
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT2B4 UGT2B15 UGT2B17

4.93e-07873320142249
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEMA4B THSD7A DIS3L RC3H1 UTP4 SIPA1L3 CNTNAP4 DGKD KLHL14

9.34e-0749373915368895
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

THBS1 ADAMTSL1 FBN1 LTBP2 MUC4 TNXB

1.92e-0617573628071719
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT2B4 UGT2B15 UGT2B17

1.93e-061273320308471
Pubmed

Fine tuning of the UPR by the ubiquitin ligases Siah1/2.

SIAH1 SIAH2

4.35e-06273224809345
Pubmed

Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.

UGT2B15 UGT2B17

4.35e-06273232660355
Pubmed

Isolation and characterisation of murine homologues of the Drosophila seven in absentia gene (sina).

SIAH1 SIAH2

4.35e-0627328404535
Pubmed

Duplicated zinc finger protein genes on the proximal short arm of the human X chromosome: isolation, characterization and X-inactivation studies.

ZXDA ZXDB

4.35e-0627328268913
Pubmed

Characterization of human homologs of the Drosophila seven in absentia (sina) gene.

SIAH1 SIAH2

4.35e-0627329403064
Pubmed

The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

UGT2B15 UGT2B17

4.35e-0627321909870
Pubmed

Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.

UGT2B15 UGT2B17

4.35e-06273224121496
Pubmed

Dimerization of hSiah proteins regulates their stability.

SIAH1 SIAH2

4.35e-06273216899216
Pubmed

Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation.

UGT2B15 UGT2B17

4.35e-0627323117546
Pubmed

Inhibition of Siah ubiquitin ligase function.

SIAH1 SIAH2

4.35e-06273218850011
Pubmed

Extensive metabolic consequences of human glycosyltransferase gene knockouts in prostate cancer.

UGT2B17 UGT2B28

4.35e-06273236347965
Pubmed

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.

UGT2B15 UGT2B17

4.35e-06273224267955
Pubmed

Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.

UGT2B15 UGT2B17

4.35e-06273222170718
Pubmed

ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.

ADAMTS10 FBN1

4.35e-06273221402694
Pubmed

Quantitative analysis of UGT2B28 mRNA expression by real-time RT-PCR and application to human tissue distribution study.

UGT2B28 UGT2B11

4.35e-06273221679149
Pubmed

Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.

UNC13B UNC13C

4.35e-06273222674279
Pubmed

Generation and analysis of Siah2 mutant mice.

SIAH1 SIAH2

4.35e-06273214645526
Pubmed

Localization of UDP glucuronosyltransferase gene(s) on mouse chromosome 5.

UGT2B15 UGT2B17

4.35e-0627323105095
Pubmed

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.

UGT2B15 UGT2B17

4.35e-06273217848572
Pubmed

SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status.

SIAH1 SIAH2

4.35e-06273226654769
Pubmed

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

UGT2B15 UGT2B17

4.35e-06273227496708
Pubmed

Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix.

FBN1 LTBP2

4.35e-06273224867584
Pubmed

Structure of human Roquin-2 and its complex with constitutive-decay element RNA.

RC3H2 RC3H1

4.35e-06273226249698
Pubmed

Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.

UGT2B15 UGT2B17

4.35e-06273228228532
Pubmed

Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium.

UGT2B15 UGT2B17

4.35e-06273215666817
Pubmed

The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.

UGT2B15 UGT2B17

4.35e-06273217698910
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

THBS1 ADAMTS3 ADAMTS20 TNXB

1.03e-056473422261194
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

UGT2B4 UGT2B15 UGT2B28 UGT2B11

1.17e-056673419898482
Pubmed

Normal p53 function in primary cells deficient for Siah genes.

SIAH1 SIAH2

1.30e-05373212417719
Pubmed

Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.

CLEC18A CLEC18C

1.30e-05373226170455
Pubmed

The substrate binding domains of human SIAH E3 ubiquitin ligases are now crystal clear.

SIAH1 SIAH2

1.30e-05373227776223
Pubmed

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.

UNC13B UNC13C

1.30e-05373223658173
Pubmed

Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines.

UGT2B15 UGT2B17

1.30e-05373226163549
Pubmed

Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation.

RC3H2 RC3H1

1.30e-05373230232334
Pubmed

Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13.

UGT2B4 UGT2B15

1.30e-0537327835904
Pubmed

Forkhead box protein A1 regulates UDP-glucuronosyltransferase 2B15 gene transcription in LNCaP prostate cancer cells.

UGT2B15 UGT2B17

1.30e-05373220736324
Pubmed

Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation.

RC3H2 RC3H1

1.30e-05373223583642
Pubmed

Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.

ADAMTS10 FBN1

1.30e-05373230201140
Pubmed

Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer.

UGT2B15 UGT2B17

1.30e-05373226385605
Pubmed

Roquin Paralogs Differentially Regulate Functional NKT Cell Subsets.

RC3H2 RC3H1

1.30e-05373228188245
Pubmed

cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily.

UGT2B4 UGT2B11

1.30e-0537328333863
Pubmed

Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions .

UGT2B4 UGT2B17

1.30e-05373229138287
Pubmed

Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.

SIAH1 SIAH2

1.30e-05373212810624
Pubmed

Pw1/Peg3 is a potential cell death mediator and cooperates with Siah1a in p53-mediated apoptosis.

SIAH1 SIAH2

1.30e-05373210681424
Pubmed

Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1/NO.

SIAH1 SIAH2

1.30e-05373225561546
Pubmed

Siah regulation of Pard3A controls neuronal cell adhesion during germinal zone exit.

SIAH1 SIAH2

1.30e-05373221109632
Pubmed

The coiled-coil domain is the structural determinant for mammalian homologues of Drosophila Sina-mediated degradation of promyelocytic leukemia protein and other tripartite motif proteins by the proteasome.

SIAH1 SIAH2

1.30e-05373214645235
Pubmed

The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice.

SIAH1 SIAH2

1.30e-05373211884614
Pubmed

Intercellular adhesion molecule-1 deficiency attenuates the development of skin fibrosis in tight-skin mice.

SELL FBN1

1.30e-05373217579093
Pubmed

Ubiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma.

SIAH1 SIAH2

1.30e-05373237078793
Pubmed

Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells.

UGT2B15 UGT2B17

1.30e-05373217988216
Pubmed

Investigating the molecular basis of Siah1 and Siah2 E3 ubiquitin ligase substrate specificity.

SIAH1 SIAH2

1.30e-05373225202994
Pubmed

LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein.

FBN1 LTBP2

1.30e-05373217293099
Pubmed

Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.

UNC13B UNC13C

1.30e-05373233105896
Pubmed

The C-type lectin-like domain superfamily.

CLEC18A CLEC18C

1.30e-05373216336259
Pubmed

Tissue distribution and relative gene expression of UDP-glucuronosyltransferases (2B7, 2B15, 2B17) in the human fetus.

UGT2B15 UGT2B17

1.30e-05373223223495
Pubmed

Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.

CLEC18A CLEC18C

1.30e-05373233603190
Pubmed

An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response.

SIAH1 SIAH2

1.30e-05373219043406
Pubmed

Siah proteins induce the epidermal growth factor-dependent degradation of phospholipase Cepsilon.

SIAH1 SIAH2

1.30e-05373217998205
Pubmed

The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer.

SIAH1 SIAH2

1.30e-05373225528765
Pubmed

Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.

UGT2B15 UGT2B17

1.30e-05373218302198
Pubmed

Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.

RC3H2 RC3H1

1.30e-05373225026077
Pubmed

Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.

UNC13B UNC13C

1.30e-05373222966208
Pubmed

The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.

UGT2B15 UGT2B17

1.30e-05373230689982
Pubmed

Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.

UNC13B UNC13C

1.30e-05373215988013
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

THBS1 FBN1 THSD7A CRB1

1.56e-057173433541421
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

BMPR2 ADAMTS3 CRB1

1.74e-052473332212159
Pubmed

Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology?

SIAH1 SIAH2

2.60e-05473215221006
Pubmed

Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia.

SIAH1 SIAH2

2.60e-05473222099302
Pubmed

Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells.

SIAH1 SIAH2

2.60e-05473218070888
Pubmed

SIAH proteins regulate the degradation and intra-mitochondrial aggregation of PINK1: Implications for mitochondrial pathology in Parkinson's disease.

SIAH1 SIAH2

2.60e-05473236307912
Pubmed

Comparative immunolocalization of the elastin fiber-associated proteins fibrillin-1, LTBP-2, and MAGP-1 with components of the collagenous and proteoglycan matrix of the fetal human intervertebral disc.

FBN1 LTBP2

2.60e-05473221540769
Pubmed

Ubiquitin-specific protease 19 (USP19) regulates hypoxia-inducible factor 1α (HIF-1α) during hypoxia.

SIAH1 SIAH2

2.60e-05473222128162
Pubmed

Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis.

RC3H2 RC3H1

2.60e-05473225697406
Pubmed

The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.

CLEC18A CLEC18C

2.60e-05473216709836
Pubmed

Histopathology of melanosis coli and determination of its associated genes by comparative analysis of expression microarrays.

UGT2B15 UGT2B11

2.60e-05473226238215
Pubmed

Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease.

SIAH1 SIAH2

2.60e-05473215064394
Pubmed

Characterization of the protein-protein interactions determining the heat shock protein (hsp90.hsp70.hsp56) heterocomplex.

SELENBP1 HSP90AB1

2.60e-0547328157642
Pubmed

Jedi-1 and MEGF10 signal engulfment of apoptotic neurons through the tyrosine kinase Syk.

MEGF10 PEAR1

2.60e-05473222993420
Pubmed

A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation.

RC3H2 RC3H1

2.60e-05473231636267
Pubmed

Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells.

UGT2B15 UGT2B17

2.60e-05473218281521
Pubmed

Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.

UGT2B15 UGT2B17

2.60e-05473226176234
Pubmed

Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins.

SIAH1 SIAH2

2.60e-0547329858595
Pubmed

Siah-1 is associated with expression of hypoxia-inducible factor-1α in oral squamous cell carcinoma.

SIAH1 SIAH2

2.60e-05473227616748
Pubmed

P-TEFb is degraded by Siah1/2 in quiescent cells.

SIAH1 SIAH2

2.60e-05473235524561
Pubmed

Regulation of BOB.1/OBF.1 stability by SIAH.

SIAH1 SIAH2

2.60e-05473211483518
Pubmed

Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway.

SIAH1 SIAH2

2.60e-0547329334332
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

THBS1 FBN1 LTBP2 TNXB

3.33e-058673428327460
Pubmed

TBX1 is required for normal stria vascularis and semicircular canal development.

THBS1 FBN1 STAB1

3.82e-053173331550482
InteractionUNC13C interactions

UNC13B UNC13C HSP90AB1

9.01e-0612713int:UNC13C
CytobandEnsembl 112 genes in cytogenetic band chr4q13

ADAMTS3 UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.05e-07157736chr4q13
Cytoband4q13

UGT2B4 UGT2B15 UGT2B17

1.73e-06157334q13
Cytoband16q22.1

CLEC18A UTP4 CLEC18C

7.37e-0411073316q22.1
Cytoband7p21.3

THSD7A VWDE

9.18e-04287327p21.3
Cytoband4q13.2

UGT2B28 UGT2B11

1.13e-03317324q13.2
CytobandEnsembl 112 genes in cytogenetic band chr16q22

CLEC18A UTP4 CLEC18C

3.16e-03183733chr16q22
GeneFamilyUDP glucuronosyltransferases

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.72e-0832545363
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS10 ADAMTS3 ADAMTS20

2.36e-051954350
GeneFamilyUNC13 homologs

UNC13B UNC13C

5.23e-054542836
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SCARF1 MEGF10 STAB1

7.00e-05275431253
GeneFamilyC-type lectin domain family

CLEC18A CLEC4E CLEC18C

3.72e-0447543494
GeneFamilyCD molecules|Mucins

MUC3B MUC4

1.77e-0321542648
GeneFamilyZinc fingers CCCH-type

RC3H2 RC3H1

4.89e-033554273
GeneFamilyRing finger proteins

RC3H2 RC3H1 NEURL1 OBI1

9.13e-0327554458
CoexpressionNABA_MATRISOME

ADAMTS10 CLEC18A SEMA4B CLEC4E THBS1 ADAMTSL1 FBN1 ADAMTS3 ADAMTS20 CLEC18C EGFLAM LTBP2 MUC4 TNXB VWDE MEGF10

1.11e-0810087216MM17056
CoexpressionNABA_MATRISOME

ADAMTS10 CLEC18A SEMA4B CLEC4E THBS1 ADAMTSL1 FBN1 ADAMTS3 ADAMTS20 CLEC18C EGFLAM LTBP2 MUC4 TNXB VWDE MEGF10

1.42e-0810267216M5889
CoexpressionSERVITJA_ISLET_HNF1A_TARGETS_DN

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11 MUC4

1.04e-06121726MM935
CoexpressionVANLOO_SP3_TARGETS_DN

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

9.65e-06103725MM919
CoexpressionNABA_ECM_GLYCOPROTEINS

THBS1 FBN1 EGFLAM LTBP2 TNXB VWDE

1.45e-05191726MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

THBS1 FBN1 EGFLAM LTBP2 TNXB VWDE

1.68e-05196726M3008
CoexpressionGSE15767_MED_VS_SCS_MAC_LN_UP

SELL THBS1 SELENBP1 HLX PROS1 STAB1

1.88e-05200726M3584
CoexpressionNABA_MATRISOME_ASSOCIATED

ADAMTS10 CLEC18A SEMA4B CLEC4E ADAMTSL1 ADAMTS3 ADAMTS20 CLEC18C MUC4 MEGF10

3.27e-057387210MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

ADAMTS10 CLEC18A SEMA4B CLEC4E ADAMTSL1 ADAMTS3 ADAMTS20 CLEC18C MUC4 MEGF10

3.79e-057517210M5885
CoexpressionWILLIAMS_ESR1_TARGETS_UP

THBS1 UGT2B17 SIAH2

4.94e-0526723M2970
CoexpressionANDERSEN_LIVER_CANCER_KRT19_DN

SELENBP1 UGT2B15 UGT2B17 SIAH2

5.49e-0575724M424
CoexpressionNABA_ECM_AFFILIATED

CLEC18A SEMA4B CLEC4E CLEC18C MUC4

7.55e-05158725MM17063
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP

THBS1 UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

9.40e-05267726MM984
CoexpressionNABA_CORE_MATRISOME

THBS1 FBN1 EGFLAM LTBP2 TNXB VWDE

9.99e-05270726MM17057
CoexpressionNABA_ECM_AFFILIATED

CLEC18A SEMA4B CLEC4E CLEC18C MUC4

1.07e-04170725M5880
CoexpressionNABA_CORE_MATRISOME

THBS1 FBN1 EGFLAM LTBP2 TNXB VWDE

1.10e-04275726M5884
CoexpressionNABA_MATRISOME_POORLY_METASTATIC_MELANOMA

THBS1 ADAMTSL1 LTBP2

1.56e-0438723M47982
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.79e-04190725MM1311
CoexpressionGSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP

SELL BMPR2 BMX GSAP ZXDB

1.88e-04192725M4174
CoexpressionGSE4142_NAIVE_VS_MEMORY_BCELL_UP

RC3H2 BMPR2 TMEM184B CRB1 WDR47

2.22e-04199725M6388
CoexpressionCHANGOLKAR_H2AFY_TARGETS_DN

UTP4 UGT2B15 UGT2B17

2.27e-0443723MM902
CoexpressionGSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN

SELL CLEC4E THBS1 LTBP2 GSAP

2.27e-04200725M4616
CoexpressionGSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_UP

CLEC4E BMPR2 HAGHL SIAH1 PROS1

2.27e-04200725M6965
CoexpressionOHGUCHI_LIVER_HNF4A_TARGETS_DN

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.33e-04201725MM1294
CoexpressionHAY_BONE_MARROW_NEUTROPHIL

SELL GLIPR1 CLEC4E THBS1 LRP3 HLX STAB1

2.36e-04450727M39203
CoexpressionGRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN

SELL GLIPR1 HLX

2.77e-0446723M11636
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11 DENND1A

2.96e-04330726MM1120
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THBS1 BMPR2 FBN1 ADAMTS3 EGFLAM TNXB PROS1

2.50e-081907270fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCellMonocytes-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

SELL GLIPR1 CLEC4E THBS1 HLX STAB1

4.15e-071767265b5f8655b0c6c56f98f70bce13e71f017d4b75a5
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

ADAMTS10 THBS1 ADAMTSL1 FBN1 NKX3-2 MEGF10

4.43e-07178726142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

SCARF1 CLEC4E THSD7A TENM3 ADAMTS3 EGFLAM

4.58e-07179726cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 ADAMTSL1 THSD7A PROS1 PEAR1 STAB1

6.50e-07190726a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 ADAMTSL1 THSD7A PROS1 PEAR1 STAB1

6.50e-071907260bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 ADAMTSL1 THSD7A PROS1 PEAR1 STAB1

6.50e-0719072626e2237f65cb43723c5da853831b40df2982d6e4
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS1 FBN1 HLX EGFLAM LTBP2 TNXB

6.70e-071917264e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 THBS1 FBN1 EGFLAM LTBP2 PROS1

7.56e-071957262514c1f23424b5fc664d326d31ffd22bafe74ef8
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 THBS1 FBN1 EGFLAM LTBP2 PROS1

7.79e-07196726e4d04e1f82779e8afd4e32bbe38d1d3f6f64ab50
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 THBS1 FBN1 EGFLAM LTBP2 PROS1

7.79e-07196726f0fd7db22985d2bc84dc8bcbdb2d552e280121dd
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 THBS1 FBN1 EGFLAM LTBP2 PROS1

8.02e-0719772626475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 THBS1 FBN1 EGFLAM LTBP2 PROS1

8.02e-07197726155e63b33302a87393ace699b2f6d73abe9c5763
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 THBS1 FBN1 EGFLAM LTBP2 PROS1

8.26e-07198726b2d295e330772bd8e24da356c75564b4297ea9c5
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 THBS1 FBN1 EGFLAM LTBP2 PROS1

8.26e-07198726ce59ee3d970397eb62d6387699c6c6cd65457898
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 THBS1 FBN1 EGFLAM LTBP2 PROS1

8.26e-07198726a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELL GLIPR1 CLEC4E THBS1 HLX STAB1

8.26e-07198726273a9e24438c31c1d3fc3ad71efbfafb54747476
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELL GLIPR1 CLEC4E THBS1 HLX STAB1

8.26e-071987269375a9fd31393709e1e3078f4b130e9e71a37c13
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 THBS1 FBN1 EGFLAM LTBP2 PROS1

8.26e-071987263ffaea4b44067d69f954b2bd3119c88a55ab232a
ToppCellParenchymal-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD14|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SELL GLIPR1 CLEC4E THBS1 HLX STAB1

8.76e-0720072647a3fd432c35958c5d478d34f5e0355e39ed0aba
ToppCellControl-Neutrophil|Control / Disease condition and Cell class

BMX NFE4 UGT2B15 MEGF10 CRB1

1.91e-06126725450c01d89714feee6529680ec3ce69067a54b37c
ToppCellControl-Neutrophil-|Control / Disease condition and Cell class

BMX NFE4 UGT2B15 MEGF10 CRB1

1.91e-0612672565fff5ec2296272e94f44546606587833191dd82
ToppCelldroplet-Fat-Gat-18m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELL GLIPR1 CLEC4E BMX HLX

6.75e-061637253d12a8ca97005308403a3ab136af483ab25f9b0e
ToppCellMonocytes-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

SELL GLIPR1 CLEC4E THBS1 STAB1

7.82e-061687259ea3c682ce4e98f1a3303f99b4c63c2cf8863abc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 TENM3 HLX PEAR1

8.52e-06171725972fab891135bd755d5526cbc5a963200067b0a6
ToppCellEndothelial-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

FBN1 TENM3 KLHL14 TNXB PEAR1

8.52e-0617172507ff7059071da83da1d8f266a586573920d75b58
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 TENM3 HLX PEAR1

8.52e-061717252a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

THSD7A TENM3 KLHL14 TNXB PEAR1

1.03e-05178725c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCellMonocytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

SELL GLIPR1 CLEC4E THBS1 STAB1

1.12e-05181725d8b98c3d9bef026a0a35948219027f27718ffbee
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

THBS1 OXCT1 NEURL1 LTBP2 VWDE

1.12e-051817254a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

THBS1 TENM3 NEURL1 UNC13C LTBP2

1.18e-05183725ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELL GLIPR1 CLEC4E THBS1 STAB1

1.21e-05184725d7f348aa8901d819c68da20728b9238407bcdca9
ToppCellMonocytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SELL GLIPR1 CLEC4E THBS1 STAB1

1.21e-05184725d15405bf2a121570f6044546e98927b10ecc4354
ToppCell5'-Adult-Distal_Rectal-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA4B NEURL1 UGT2B4 MUC4 LYPD8

1.28e-051867254046b701aa29712d9f7c774f8955215122c3c003
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SCARF1 BMX ARHGAP27 KLHL14 STAB1

1.28e-051867255d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 FBN1 NKX3-2 LTBP2 TNXB

1.28e-051867255473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell5'-Adult-Distal_Rectal-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA4B NEURL1 UGT2B4 MUC4 LYPD8

1.28e-05186725bd5837033c1ffcbe5dd30195cc4846a2ba351bcd
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THSD7A ADAMTS20 KLHL14 TNXB PEAR1

1.28e-0518672520340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SCARF1 BMX ARHGAP27 KLHL14 STAB1

1.28e-051867251da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCellMonocytes-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

SELL GLIPR1 CLEC4E THBS1 NEURL1

1.38e-051897252164adbe1b0e8e4d39644546b7dfb19e9ea4f7b9
ToppCellCOVID-19_Severe-Myeloid_G-Neutrophil|COVID-19_Severe / Disease group, lineage and cell class

SCARF1 SELL CLEC4E BMX NFE4

1.38e-05189725a62f4c445ede00d15b74bee65f4e4fb54cfd4d32
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCARF1 SELL CLEC4E BMX NFE4

1.38e-05189725f6b2b4824505f0119a017fdb73c55418fb651645
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SCARF1 SELL CLEC4E BMX NFE4

1.38e-05189725db8e314ce95c32542bb4015a77032a33211fea0b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLIPR1 TENM3 GPR149 DGKD TAFA4

1.38e-0518972599a13b1b669b0cd36e3096632351d9ade25d1173
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

BMPR2 BMX ADAMTSL1 THSD7A DENND1A

1.38e-0518972575c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

BMPR2 BMX ADAMTSL1 THSD7A DENND1A

1.38e-05189725c81787a8c662db5d7814c583dd64562857629e81
ToppCellIPF-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

SELL CLEC4E THBS1 HLX DGKD

1.38e-05189725ad7bb3a7de8e48c145e4382f90d30bb2159c2b76
ToppCellMonocytes-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

SELL GLIPR1 THBS1 HLX STAB1

1.38e-0518972522d08c7dde697f385100f72e009eeac8d19d329d
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

THBS1 FBN1 TENM3 LTBP2 TNXB

1.42e-051907253a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLIPR1 TENM3 GPR149 DGKD TAFA4

1.42e-051907258c9c230a509afaeee50644153974a5642b01a2b8
ToppCellPSB-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

THBS1 TENM3 NEURL1 UNC13C LTBP2

1.45e-051917258f4637e801554e2343b974fe7794f01dd2151418
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTSL1 FBN1 TENM3 LRP3 TNXB

1.45e-05191725b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 FBN1 THSD7A EGFLAM TNXB

1.45e-05191725b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 THSD7A PROS1 PEAR1 STAB1

1.45e-0519172548823a97c38263f2c6e58348214f5b62773a6368
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 THSD7A PROS1 PEAR1 STAB1

1.45e-051917250eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

BMX ADAMTSL1 THSD7A UNC13C DENND1A

1.49e-05192725c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCelldroplet-Kidney-nan-18m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 FBN1 EGFLAM LTBP2 TNXB

1.49e-0519272538d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 FBN1 EGFLAM LTBP2 TNXB

1.49e-0519272504d155897ed075c359933080e36a4ab2150b6e9f
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 FBN1 EGFLAM LTBP2 TNXB

1.49e-0519272584149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

FBN1 TENM3 UGT2B4 LTBP2 TNXB

1.53e-05193725ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellMonocytes|World / lung cells shred on cell class, cell subclass, sample id

SELL GLIPR1 CLEC4E THBS1 STAB1

1.53e-05193725d66d3927f8fbe1544b5cfa5ee91a7f4a0ef1e810
ToppCellControl-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

SELL CLEC4E THBS1 HLX STAB1

1.57e-05194725f852f5258617a66a4fbd56d64c7b47272e7b8b60
ToppCellMonocytes-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

SELL GLIPR1 THBS1 HLX STAB1

1.57e-05194725ed14fbb3b4622798f8e02dc91bbe464a6fed8310
ToppCelldistal-Hematologic-Classical_Monocyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SELL GLIPR1 CLEC4E THBS1 STAB1

1.61e-0519572532c34741e35006b7238896fd04a497011297dd22
ToppCellMNPs-Monocytes|MNPs / lung cells shred on cell class, cell subclass, sample id

SELL GLIPR1 CLEC4E THBS1 STAB1

1.61e-0519572545e8d27287bdfd07d7e944ae5d3f44d05c33468f
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 NKX3-2 HLX UGT2B11 HSP90AB1

1.65e-05196725fd0a2b863dedaf08d18e7f67da18ac7e853991e4
ToppCellcellseq-Immune-Immune_Myeloid-iMON|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SELL GLIPR1 CLEC4E THBS1 STAB1

1.65e-051967255842d6fa0c066815d7d8c7e59b192bfc72960707
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_capillary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCARF1 BMX THSD7A PEAR1 STAB1

1.65e-05196725f0b106078212be1d0938f545707a004a1e830857
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Neutrophils|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

SELL GLIPR1 CLEC4E THBS1 STAB1

1.65e-05196725376c5a459a484205fbb0db34936e4a6146d1f622
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 ADAMTSL1 FBN1 TENM3 TNXB

1.65e-051967252b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellcellseq-Immune-Immune_Myeloid-iMON-iMON|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SELL GLIPR1 CLEC4E THBS1 STAB1

1.65e-051967258608be3c3e7fd776c5f2fae207cd0b801e138349
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELL GLIPR1 CLEC4E THBS1 STAB1

1.65e-05196725555c9e443fe3b9893cb320b78d84002e1f8c1701
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELL GLIPR1 CLEC4E THBS1 STAB1

1.65e-05196725a1b21f4667c05e837a1229cc5934db805ad562c5
ToppCellmedial-2-Hematologic-Classical_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SELL GLIPR1 CLEC4E THBS1 STAB1

1.69e-05197725fbff79d6ece1605126ae0caa0c71253ea557779c
ToppCellmedial-Hematologic-Classical_Monocyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SELL GLIPR1 CLEC4E THBS1 STAB1

1.69e-051977253960eac4b6753e3294e13901f6ea13d894275c8d
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BMX FBN1 THSD7A HLX GRM2

1.69e-05197725ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 ADAMTSL1 NKX3-2 HLX HSP90AB1

1.69e-051977255f6fce382f273e789ffbb75b63e9b4e87519918e
ToppCellInfluenza_Severe-Classical_Monocyte|World / Disease group and Cell class

SELL CLEC4E THBS1 HLX STAB1

1.69e-05197725e9a01f0fbbeaf6b23bce4603f62053c003848da4
ToppCellmedial-Hematologic-Classical_Monocyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SELL GLIPR1 CLEC4E THBS1 STAB1

1.69e-05197725ae2b51d4e91126ee0a0f69c040297c2a78ce27dd
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELL GLIPR1 CLEC4E THBS1 STAB1

1.69e-05197725f431f11196dc4332933b5d71c7c7408d54c2dedc
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS1 FBN1 LTBP2 MEGF10 PROS1

1.69e-05197725090a251194da3e2806989d9a522588f83f52da7f
ToppCelldistal-2-Hematologic-Classical_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SELL GLIPR1 CLEC4E THBS1 HLX

1.69e-051977259a1c9221904ad1e46e64e3785516804e87128adc
ToppCell390C-Endothelial_cells|390C / Donor, Lineage, Cell class and subclass (all cells)

SCARF1 BMPR2 BMX THSD7A PEAR1

1.69e-05197725aa381acea0f7882d39435a6f713386bf0588b5f8
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 THBS1 FBN1 EGFLAM LTBP2

1.69e-051977258c728cd3c0382c4f3e4b78647b6e1447bb40ace1
ToppCelldistal-Hematologic-Classical_Monocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SELL GLIPR1 CLEC4E THBS1 STAB1

1.69e-051977259f4b0857012cd503e668bac115010216a946f73c
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELL GLIPR1 CLEC4E THBS1 STAB1

1.73e-05198725d5c816fb894f55acbbab188e6262668acc422fb9
ToppCellproximal-Hematologic-Classical_Monocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SELL GLIPR1 CLEC4E THBS1 STAB1

1.73e-051987256a7ca6eef6b74aa7fc3aec84e9ffd0beedaa589b
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELL GLIPR1 THBS1 HLX STAB1

1.73e-05198725a7145565703d0e036d2dcef5dba6d86f200845c9
ToppCellTracheal-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCARF1 BMX KLHL14 PEAR1 STAB1

1.73e-0519872505429f18e1d74880c1835568c86177f661b3477a
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 THBS1 FBN1 EGFLAM LTBP2

1.73e-051987250993d6895c0e4f360998ce35abea4ec3dd13e048
ToppCellTracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCARF1 BMX KLHL14 PEAR1 STAB1

1.73e-05198725306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCellproximal-3-Hematologic-Classical_Monocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SELL GLIPR1 CLEC4E THBS1 STAB1

1.73e-051987256c6a63b8ec03b7a8f46b70bf13261fab56355f92
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

ADAMTSL1 FBN1 EGFLAM LTBP2 TNXB

1.73e-05198725bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELL GLIPR1 CLEC4E THBS1 STAB1

1.73e-051987256d547122b8c4ddbdd0d3dae3bce4a125740d5457
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELL GLIPR1 CLEC4E THBS1 STAB1

1.73e-05198725c288b29287a562460d8970264e1833801590da73
ToppCellproximal-Hematologic-Classical_Monocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SELL GLIPR1 CLEC4E THBS1 STAB1

1.73e-0519872598bd2b3e03ab659ce163d5773660ce008e4cc2ca
ToppCellCOVID-19_Mild-Classical_Monocyte|COVID-19_Mild / Disease condition and Cell class

SELL CLEC4E THBS1 HLX STAB1

1.73e-0519872530ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCell3'_v3-Lung-Myeloid_Monocytic|Lung / Manually curated celltypes from each tissue

SELL GLIPR1 THBS1 HLX STAB1

1.77e-051997253e14f9a62d6414add8d5f681be184b4625001838
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 ADAMTSL1 NKX3-2 HLX HSP90AB1

1.77e-05199725bb201deb281619113edcd1de2af2d3eb21b967b8
ToppCelldistal-3-Hematologic-Classical_Monocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SELL GLIPR1 CLEC4E THBS1 STAB1

1.77e-05199725cd7c304076d14315dc24cf56eb5e06b9426710be
DrugC1 11-32

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.28e-0918725CID000443077
DrugC11131

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.28e-0918725CID000443076
DrugT4-G

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.08e-0919725CID000152424
Drugestriol-16-glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

5.37e-0921725CID000122281
Drugestradiol-3-glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

8.84e-0923725CID000066651
DrugHymecromone

FBN1 UGT2B4 UGT2B15 UGT2B17 UGT2B11

1.39e-0825725ctd:D006923
DrugL-idaro-1,4-lactone

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.55e-0828725CID000078997
Drug7-hydroxycoumarin glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.07e-0829725CID000125641
DrugAC1Q6OQG

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

6.08e-0833725CID000009686
DrugBP-3,6-quinol

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

6.08e-0833725CID000119292
DrugAC1NOWCJ

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

8.28e-0835725CID005120112
Drug3-[(3S,5R,10S,13R,14S,17R)-3-[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

8.28e-0835725CID010436171
Drugestrone-3-glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

8.28e-0835725CID000115255
Drugl-borneol

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.11e-0737725CID000010049
Drugharmol

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.66e-0740725CID000068094
Drugtestosterone glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.88e-0741725CID000108192
Drug2-AF

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.88e-0741725CID000005800
Drugandrosterone glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.41e-0743725CID000114833
Drug7,8-benzoquinoline

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.41e-0743725CID000009191
DrugMS-222

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.71e-0744725CID000011400
Drugmenthol

UGT2B4 UGT2B15 UGT2B17 UGT2B28 GRM2 UGT2B11

3.34e-0787726CID000001254
Drugsalicylamide

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

4.23e-0748725CID000005147
DrugAC1NQGK1

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

6.36e-0752725CID005195977
Drugoxazepam

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

7.00e-0753725CID000004616
Drug7-methoxycoumarin

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.01e-0657725CID000010748
Drugphenolphthalein

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.10e-0658725CID000004764
Drugurochloralic acid

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.20e-0659725CID003036914
Drug4-hydroxybiphenyl

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.20e-0659725CID000007103
Drug4-hydroxyestrone

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.20e-0659725CID000018418
Drugacetaminophen glucuronide

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.20e-0659725CID000083944
DrugSN-38G

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.20e-0659725CID000443154
DrugUDP-alpha-d-xylopyranose

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.31e-0660725CID000001165
Drug3-OHBaP

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.67e-0663725CID000025890
DrugMeldola

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.45e-0668725CID000081507
Drugmethoxyresorufin

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.64e-0669725CID000119220
Drug2,2,2-trichloroethanol

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.49e-0673725CID000008259
Drugeugenol

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.49e-0673725CID000003314
Drug4-methylumbelliferone

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11 MUC4

3.87e-06132726CID003364573
Drug7-hydroxycoumarin

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.99e-0675725CID005281426
Drug16-epiestriol

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

4.55e-0677725CID000003269
DrugAC1N8H7N

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

4.85e-0678725CID004318740
Drugbenzyloxyresorufin

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

4.85e-0678725CID000114982
Drugacridine

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

5.84e-0681725CID000009215
Drugchondroitin sulfate

SELL THBS1 ADAMTS3 UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11 TNXB

6.04e-06413729CID000024766
Drug5 alpha-androstane

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

6.98e-0684725CID000094144
Drug7-ethoxycoumarin

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

7.84e-0686725CID000035703
Drugpentoxyresorufin

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

8.30e-0687725CID000107683
Drug4-aminobiphenyl

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.09e-0592725CID000007102
Drugp-nitroanisole

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.09e-0592725CID000007485
Drug2-naphthol

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.15e-0593725CID000008663
DrugDCNB

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.28e-0595725CID000007443
Drugethoxyresorufin

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.28e-0595725CID000003294
Drugal-Badry

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11 HSP90AB1

1.39e-05165726CID000004545
DrugDB04103

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.41e-0597725CID004469987
Drug1-naphthol

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.48e-0598725CID000007005
Drug3-hydroxyandrostan-17-one

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.80e-05102725CID000000225
Drugchrysin

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.17e-05106725CID005281607
Drugfluconazole

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.27e-05107725CID000003365
DrugSN-38

THBS1 UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.58e-05184726CID000104842
Drug2-naphthylamine

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.60e-05110725CID000007057
Druguridine 5'-diphosphoglucuronic acid

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11 CRB1

3.00e-05189726CID000000390
DrugAC1L1OBF

UGT2B4 UGT2B15 UGT2B17

3.33e-0520723CID000032736
Druglithocholic acid

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.35e-05116725CID000009903
Drugethoxyquin

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.35e-05116725CID000003293
DrugAC1Q7AUJ

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.50e-05117725CID000003303
Drugfibrates

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.64e-05118725CID000002797
Drugalpha-naphthoflavone

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.64e-05118725CID000011790
Drugbenzphetamine

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.79e-05119725CID000002341
Drugsodium cholate

THBS1 UGT2B4 LRP3 UGT2B15 UGT2B17 UGT2B28 UGT2B11 MUC4

4.37e-05408728CID000000303
Drughexobarbital

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

5.18e-05127725CID000003608
DrugAC1L1FK5

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

5.58e-05129725CID000003272
Drugoltipraz

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

7.42e-05137725CID000047318
Druglicochalcone A

UGT2B4 UGT2B15 UGT2B17

8.40e-0527723ctd:C070840
Druganiline

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

8.79e-05142725CID000006115
Drugbutylated hydroxytoluene

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

9.09e-05143725CID000031404
Drug2 E1

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

9.71e-05145725CID006102788
DrugAmobarbital

UGT2B4 UGT2B15

9.80e-055722ctd:D000654
Drugphenolphthalin

UGT2B4 UGT2B15

9.80e-055722CID000066494
DrugNNAL

UGT2B4 UGT2B15 UGT2B17

1.41e-0432723CID000104856
Drugdisulfiram

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.45e-04158725CID000003117
Druglorcaserin

UGT2B15 UGT2B17

1.47e-046722ctd:C506658
DrugR(-)-Denopamine

UGT2B4 UGT2B15 UGT2B17

1.55e-0433723CID000003818
DrugAC1LCF1F

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.59e-04161725CID000627275
Drugestrone-d4

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

1.93e-04168725CID000000698
Drugranirestat

UGT2B4 UGT2B15

2.05e-047722ctd:C115070
Drugaminopyrine

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.10e-04171725CID000006009
Drugglucosiduronate

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.10e-04171725CID000000610
Drugacetaminophen

SELENBP1 UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.13e-04270726CID000001983
Drug4-nitrophenol

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

2.46e-04177725CID000000980
DrugEburnamonine (-) [4880-88-0]; Up 200; 13.6uM; PC3; HT_HG-U133A

GLIPR1 THBS1 ADAMTS3 SIPA1L3 OBI1

2.80e-041827257154_UP
Drugretinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA

UNC13B THBS1 LRP3 DGKD WDR47

3.02e-041857251049_DN
DrugDNCB

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.33e-04189725CID000000006
Drug4-phenylphenol

UGT2B15 UGT2B11

3.50e-049722ctd:C019046
DrugLasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; HL60; HT_HG-U133A

UNC13B GLIPR1 BMPR2 SIPA1L3 LTBP2

3.76e-041947253021_DN
Drugdimethylnitrosamine

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

3.94e-04196725CID000006124
DrugTodralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; HL60; HT_HG-U133A

RC3H2 THBS1 CIAO1 SIPA1L3 SIAH1

3.94e-041967251841_DN
DrugOzagrel hydrochloride [78712-43-3]; Down 200; 15.2uM; HL60; HT_HG-U133A

BMPR2 THSD7A SIPA1L3 NKX3-2 LTBP2

3.94e-041967252942_DN
Drug2-butyl-6-methoxyphenol

UGT2B4 UGT2B15 UGT2B17 UGT2B28 UGT2B11

4.03e-04197725CID011954184
DrugCarcinine [56897-53-1]; Up 200; 22uM; HL60; HT_HG-U133A

UNC13B GLIPR1 CLEC4E THBS1 SIPA1L3

4.03e-041977251305_UP
DrugMepenzolate bromide [76-90-4]; Up 200; 9.6uM; PC3; HT_HG-U133A

CLEC4E BMX NKX3-2 ADAMTS20 GRM2

4.13e-041987253748_UP
DiseaseWeill-Marchesani syndrome

ADAMTS10 FBN1 LTBP2

1.22e-083693C0265313
DiseaseWeill-Marchesani Syndrome, Autosomal Dominant

ADAMTS10 FBN1 LTBP2

1.22e-083693C1869115
DiseaseWeill-Marchesani Syndrome, Autosomal Recessive

ADAMTS10 FBN1 LTBP2

1.22e-083693C1869114
DiseaseX-19141 measurement

UGT2B4 UGT2B15 UGT2B17 UGT2B11

1.93e-0813694EFO_0800799
DiseaseWeill-Marchesani syndrome

ADAMTS10 FBN1 LTBP2

4.89e-084693cv:C0265313
DiseaseWeill-Marchesani syndrome (is_implicated_in)

ADAMTS10 FBN1 LTBP2

4.89e-084693DOID:0050475 (is_implicated_in)
DiseaseX-24947 measurement

UGT2B4 UGT2B15 UGT2B17 UGT2B11

1.94e-0722694EFO_0800910
Diseaseplasma clozapine-to-N-desmethylclozapine ratio measurement

UGT2B4 UGT2B15 UGT2B11

1.02e-069693EFO_0600040
Diseasephosphatidylcholine 36:4 measurement

UGT2B4 UGT2B28 UGT2B11

9.74e-0618693EFO_0010382
Diseaseandrosterone glucuronide measurement

UGT2B4 UGT2B15 UGT2B17

1.36e-0520693EFO_0800317
DiseaseWeill-Marchesani syndrome (implicated_via_orthology)

ADAMTS10 FBN1

1.61e-053692DOID:0050475 (implicated_via_orthology)
Diseasecholic acid glucuronide measurement

UGT2B15 UGT2B17

1.61e-053692EFO_0800574
Diseaseresponse to angiotensin-converting enzyme inhibitor, response to angiotensin receptor blocker, angioedema

ADAMTSL1 THSD7A VWDE

3.06e-0526693EFO_0005325, EFO_0005532, EFO_0010735
DiseaseX-25937 measurement

UGT2B15 UGT2B17

3.22e-054692EFO_0800937
Diseaseneuroticism measurement

UNC13B THSD7A TENM3 LTBP2 ARHGAP27 TAFA4 TNXB OBI1 CRB1 STAB1

4.81e-059096910EFO_0007660
DiseaseX-24574 measurement

UGT2B15 UGT2B17

1.12e-047692EFO_0800897
DiseaseX-24418 measurement

UGT2B4 UGT2B15

1.12e-047692EFO_0800879
Diseasevanillylmandelate (VMA) measurement

UGT2B4 UGT2B15

1.12e-047692EFO_0800119
Diseasedeoxycholic acid glucuronide measurement

UGT2B15 UGT2B17

1.50e-048692EFO_0800575
DiseaseX-12844 measurement

UGT2B4 UGT2B15

1.92e-049692EFO_0021339
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

UGT2B15 UGT2B17

2.40e-0410692EFO_0022090
DiseaseDNA repair protein RAD51 homolog 4 measurement

UGT2B15 UGT2B17

2.92e-0411692EFO_0801531
DiseaseMarfan Syndrome

FBN1 LTBP2

2.92e-0411692C0024796
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

UGT2B15 UGT2B17

3.50e-0412692EFO_0800291
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

UGT2B15 UGT2B17

4.13e-0413692EFO_0800293
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

UGT2B15 UGT2B17

4.82e-0414692EFO_0800283
Diseasealkaline phosphatase measurement

SEMA4B ADAMTSL1 UGT2B4 UGT2B15 UGT2B17 UNC13C LTBP2 UGT2B11 VWDE

5.79e-041015699EFO_0004533
Diseaseurate measurement, bone density

GLIPR1 GPR149 RC3H1 SIAH1 DGKD DENND1A TNXB

6.05e-04619697EFO_0003923, EFO_0004531
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

UGT2B15 UGT2B17

8.05e-0418692EFO_0800288
Diseaseetiocholanolone glucuronide measurement

UGT2B15 UGT2B17

8.98e-0419692EFO_0800362
Diseaseintraocular pressure measurement

FBN1 THSD7A NEURL1 ADAMTS20 LTBP2 TNXB

1.22e-03509696EFO_0004695
Diseaseblood zinc measurement

SIPA1L3 TAFA4

1.32e-0323692EFO_0007584
Diseaseepiandrosterone sulfate measurement

UGT2B15 UGT2B17

1.56e-0325692EFO_0021120
Diseaseanxiety

LTBP2 ARHGAP27 DENND1A STAB1

1.87e-03223694EFO_0005230
Diseasecortical surface area measurement, neuroimaging measurement

THBS1 ADAMTS3 ADAMTS20 DENND1A

1.99e-03227694EFO_0004346, EFO_0010736
DiseaseC-X-C motif chemokine 10 measurement

TENM3 ADAMTS3 UGT2B15

2.15e-03109693EFO_0008056
Diseasecorneal topography

FBN1 ADAMTS3 ADAMTS20

2.15e-03109693EFO_0004345
Diseasediverticular disease

FAM185A UGT2B4 HLX UGT2B11

2.30e-03236694EFO_0009959

Protein segments in the cluster

PeptideGeneStartEntry
DYTWGGSRCQCTLGK

EGFLAM

361

Q63HQ2
CGSSTYMCLPANWTG

nan

341

Q9N2K0
CGSSTYMCLPANWTG

nan

341

Q9N2J8
SCKAAPGCTLWEAYA

BMX

136

P51813
TCADCGLGYWPNASL

GRM2

536

Q14416
YWGGSSPDLQKCTCG

CNTNAP4

711

Q9C0A0
YAPWTKCSAQCAGGS

ADAMTS10

831

Q9H324
PWEPYSSCSRTCGGG

ADAMTS20

561

P59510
CACTSVTDLTYWGPA

NFE4

61

Q86UQ8
YSPWSCGTIGSCINA

RC3H2

836

Q9HBD1
SPWSCDTIGSYIGTK

RC3H1

811

Q5TC82
ASTTPSCGWREYGCC

HAGHL

256

Q6PII5
SCGWREYGCCPGAST

HAGHL

261

Q6PII5
EYGCCPGASTVTWTL

HAGHL

266

Q6PII5
ACKPGWSGLYCNETC

MEGF10

386

Q96KG7
RSCQCYPGWIGSDCS

MEGF10

686

Q96KG7
AYDGECKCTPGWTGL

MEGF10

726

Q96KG7
DHITGTCYCSPGWKG

MEGF10

811

Q96KG7
SFTSWRGGVCCSYGP

MUC4

4611

Q99102
SSPCCIVTSTYGWTA

HSP90AB1

586

P08238
YPTWPYKRGATCSAC

GLIPR1

181

P48060
LWSAAYCSSAGPGGC

HLX

16

Q14774
CWACQARPYSSGGSE

FAM185A

31

Q8N0U4
PWSECSRTCGGGASY

ADAMTSL1

41

Q8N6G6
TCYCLAGWTGPDCSQ

PEAR1

636

Q5VY43
SPKTGFWDCCSTSYA

OBI1

461

Q5W0B1
GYCLPWEQPCGSSSD

LRP3

366

O75074
YTASCQPWSCSGHGE

SELL

156

P14151
VRTPWGCLVDCSSSY

GPR149

176

Q86SP6
YCLPGWALSTCAAAA

NKX3-2

316

P78367
GSLCVCYSPKCASWG

GSAP

291

A4D1B5
LKSWSQCSKPCGGGF

ADAMTS3

851

O15072
KSSTICYCPEKGTWT

KLHL14

586

Q9P2G3
NTAGSFKCSCSPGWI

FBN1

1341

P35555
ISCGPDSCSEWKPGS

DIS3L

911

Q8TF46
GTILCSKGSTCYGLW

BMPR2

56

Q13873
CGTWKCENSPGSYRC

LTBP2

1271

Q14767
SNGTSCHGKPWKCYE

LYPD8

131

Q6UX82
MAAPGSCALWSYCGR

COQ5

1

Q5HYK3
SDGFWKASCPPSCTS

DGKD

306

Q16760
SGAKSCFCILSYLPW

DENND1A

91

Q8TEH3
WDDFSCSCPALTSGK

CRB1

906

P82279
WDGLKCQCPSTFYGS

MUC3B

906

Q9H195
CKVLPDYSGWSCSSG

TAFA4

116

Q96LR4
SCISPCGSWIAYSTV

UTP4

396

Q969X6
PQYCGTKSGSVLPCW

TBR1

551

Q16650
PYSDWTSCPSSCKEG

THSD7A

776

Q9UPZ6
GTCCLWGKTYSIGFL

TMEM184B

156

Q9Y519
CGLSKSYCQSGPFRW

FER1L5

1586

A0AVI2
GSFKACSVAGSWVCP

ARHGAP27

176

Q6ZUM4
LLARDPYCAWSGSSC

SEMA4B

536

Q9NPR2
CYCGDVIGWTPDSST

SIPA1L3

911

O60292
YSCPCPGASCKWQGS

SIAH1

126

Q8IUQ4
YSCPCPGASCKWQGS

SIAH2

166

O43255
GWNTCSSCFGDSTKS

SELENBP1

76

Q13228
SARGSGATWYKGCVC

OXCT1

16

P55809
GATWYKGCVCSFSTS

OXCT1

21

P55809
DGKASFTCTCKPGWQ

PROS1

136

P07225
VCSAGYWGPSCNASC

SCARF1

371

Q14162
GSDPSWKCICTLSGF

CIAO1

236

O76071
YGSGSVKNCCPLNWE

CLEC4E

71

Q9ULY5
VPYKKGAWCSLCTAS

CLEC18A

196

A5D8T8
VPYKKGAWCSLCTAS

CLEC18C

196

Q8NCF0
QCKPGWYGPTCSTAL

VWDE

1411

Q8N2E2
KGSIYCVAWSPCGQL

WDR47

661

O94967
CPLGGCGWTFTTSYK

ZXDB

306

P98169
CFAGVKCTSYPDGSW

THBS1

556

P07996
KCTSYPDGSWKCGAC

THBS1

561

P07996
TTPTYCYECEGLLWG

UNC13C

1106

Q8NB66
TPGLGQWSDECTICY

NEURL1

511

O76050
CYFSSGSCGKVLVWP

UGT2B4

16

P06133
RCVCWPGYTGEDCST

TNXB

356

P22105
CWPGYTGTDCGSRAC

TNXB

421

P22105
VTTTWKPSCCPGHYG

STAB1

1951

Q9NY15
CFSGWKGTECDVPTT

TENM3

566

Q9P273
TTPTYCYECEGLLWG

UNC13B

486

O14795
CYFSSGSCGKVLVWA

UGT2B11

16

O75310
KCPLGGCGWTFTTSY

ZXDA

301

P98168
CYFSSGSCGKVLVWP

UGT2B15

16

P54855
CYFSSGSCGKVLVWT

UGT2B28

16

Q9BY64
SSCYFCGLSWLAAGG

PIGG

496

Q5H8A4
CYFSSGSCGKVLVWP

UGT2B17

16

O75795
PYACLECGKRFSWSS

ZNF787

121

Q6DD87