Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionCD4 receptor binding

PLSCR4 PLSCR2 PLSCR1

8.22e-0611753GO:0042609
GeneOntologyMolecularFunctionlead ion binding

PLSCR2 PLSCR1

4.17e-053752GO:0032791
GeneOntologyMolecularFunctionphospholipid scramblase activity

PLSCR4 PLSCR2 PLSCR1

8.54e-0523753GO:0017128
GeneOntologyMolecularFunctiontransporter activity

PLSCR4 SLC4A8 SLC10A2 SLC12A4 SLC39A3 KCNJ2 KCNJ3 SCN10A CACNA1H PLSCR2 FXYD3 SLC1A4 PLSCR1 SLC2A3

2.78e-0412897514GO:0005215
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC4A8 SLC10A2 SLC12A4 SLC39A3 KCNJ2 KCNJ3 SCN10A CACNA1H

3.51e-04465758GO:0046873
GeneOntologyMolecularFunctionmercury ion binding

PLSCR2 PLSCR1

3.84e-048752GO:0045340
GeneOntologyMolecularFunctionepidermal growth factor receptor binding

MS4A1 PLSCR2 PLSCR1

4.90e-0441753GO:0005154
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC4A8 SLC10A2 SLC12A4 SLC39A3 KCNJ2 KCNJ3 SCN10A CACNA1H FXYD3 SLC1A4

5.22e-047587510GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC4A8 SLC10A2 SLC12A4 SLC39A3 KCNJ2 KCNJ3 SCN10A CACNA1H FXYD3 SLC1A4

7.40e-047937510GO:0015075
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

PLSCR4 PLSCR2 PLSCR1

9.31e-0451753GO:0140303
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC4A8 SLC12A4 FXYD3 SLC1A4

1.26e-03125754GO:0015108
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization

KCNJ2 KCNJ3

1.42e-0315752GO:0086008
GeneOntologyMolecularFunctionnuclear receptor activity

THRA ESR1 VDR

1.49e-0360753GO:0004879
GeneOntologyMolecularFunctionligand-activated transcription factor activity

THRA ESR1 VDR

1.57e-0361753GO:0098531
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

KCNJ3 SCN10A

1.83e-0317752GO:0099508
GeneOntologyMolecularFunctionmagnesium ion binding

ADCY10 MSH6 PKLR PLSCR2 PLSCR1

2.37e-03247755GO:0000287
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC4A8 SLC10A2 SLC12A4 SLC39A3 KCNJ2 KCNJ3 SCN10A CACNA1H

2.40e-03627758GO:0022890
GeneOntologyMolecularFunctionsymporter activity

SLC4A8 SLC10A2 SLC12A4 SLC1A4

2.46e-03150754GO:0015293
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC4A8 SLC12A4 FXYD3 SLC1A4

2.52e-03151754GO:0008509
GeneOntologyMolecularFunctionphospholipid transporter activity

PLSCR4 PLSCR2 PLSCR1

2.72e-0374753GO:0005548
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC4A8 SLC10A2 SLC12A4 SLC39A3 KCNJ2 KCNJ3 SCN10A CACNA1H

3.41e-03664758GO:0008324
GeneOntologyMolecularFunctionchannel activity

SLC12A4 KCNJ2 KCNJ3 SCN10A CACNA1H FXYD3 SLC1A4

3.54e-03525757GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC12A4 KCNJ2 KCNJ3 SCN10A CACNA1H FXYD3 SLC1A4

3.58e-03526757GO:0022803
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC4A8 SLC12A4 FXYD3 SLC1A4

3.93e-03171754GO:0015103
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC4A8 SLC10A2 SCN10A CACNA1H

3.93e-03171754GO:0015081
GeneOntologyMolecularFunctionvirus receptor activity

PLSCR2 PLSCR1 CLDN1

4.03e-0385753GO:0001618
GeneOntologyMolecularFunctionexogenous protein binding

PLSCR2 PLSCR1 CLDN1

4.17e-0386753GO:0140272
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN10A CACNA1H

4.27e-0326752GO:0005248
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC4A8 SLC10A2 SLC12A4 SLC39A3 KCNJ2 KCNJ3 SCN10A CACNA1H FXYD3 SLC1A4 SLC2A3

4.42e-0311807511GO:0022857
GeneOntologyMolecularFunctiontransition metal ion binding

ADCY10 TES SLC4A8 THRA ADAMTS9 DTNA CYP3A43 ESR1 PLSCR2 PLSCR1 VDR

4.67e-0311897511GO:0046914
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

KCNJ2 KCNJ3 SCN10A CACNA1H

4.91e-03182754GO:0005244
GeneOntologyMolecularFunctioninward rectifier potassium channel activity

KCNJ2 KCNJ3

4.94e-0328752GO:0005242
GeneOntologyMolecularFunctionvoltage-gated channel activity

KCNJ2 KCNJ3 SCN10A CACNA1H

5.10e-03184754GO:0022832
GeneOntologyBiologicalProcessactin filament-based movement

ADCY10 MYO6 KCNJ2 KCNJ3 SCN10A CACNA1H

2.15e-05153766GO:0030048
GeneOntologyBiologicalProcessimport across plasma membrane

SLC12A4 MS4A1 KCNJ2 KCNJ3 CACNA1H SLC1A4 SLC2A3

2.23e-05230767GO:0098739
GeneOntologyBiologicalProcesscardiac muscle cell contraction

ADCY10 KCNJ2 KCNJ3 SCN10A CACNA1H

2.40e-0593765GO:0086003
GeneOntologyBiologicalProcessmetal ion transport

SLC4A8 SLC10A2 SLC12A4 SLC39A3 MS4A1 KCNJ2 KCNJ3 SCN10A CD63 CACNA1H FXYD3 CXCL11 VDR

6.74e-0510007613GO:0030001
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC4A8 SLC12A4 SLC39A3 MS4A1 KCNJ2 KCNJ3 SCN10A CD63 CACNA1H FXYD3 CXCL11 SLC1A4 VDR

7.99e-0510177613GO:0098660
GeneOntologyBiologicalProcessresponse to lead ion

PTH PLSCR1 CLDN1

1.04e-0425763GO:0010288
GeneOntologyBiologicalProcessactin-mediated cell contraction

ADCY10 KCNJ2 KCNJ3 SCN10A CACNA1H

1.06e-04127765GO:0070252
GeneOntologyBiologicalProcessplasma membrane phospholipid scrambling

PLSCR4 PLSCR2 PLSCR1

1.18e-0426763GO:0017121
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC4A8 SLC12A4 FXYD3 SLC1A4 VDR

1.37e-04134765GO:0098661
GeneOntologyBiologicalProcessstriated muscle contraction

ADCY10 DTNA KCNJ2 KCNJ3 SCN10A CACNA1H

1.50e-04217766GO:0006941
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

SLC12A4 MS4A1 KCNJ2 KCNJ3 CACNA1H

1.80e-04142765GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

SLC12A4 MS4A1 KCNJ2 KCNJ3 CACNA1H

1.80e-04142765GO:0098659
GeneOntologyBiologicalProcessmammary gland branching involved in pregnancy

ESR1 VDR

2.78e-047762GO:0060745
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC4A8 SLC10A2 SLC12A4 SLC39A3 MS4A1 KCNJ2 KCNJ3 SCN10A CD63 CACNA1H FXYD3 CXCL11 VDR

2.87e-0411577613GO:0006812
GeneOntologyBiologicalProcessregulation of transmembrane transport

MS4A1 KCNJ2 KCNJ3 ESR1 SCN10A CD63 FXYD3 CXCL11 PTH

3.08e-04589769GO:0034762
GeneOntologyBiologicalProcessmembrane depolarization during action potential

KCNJ2 SCN10A CACNA1H

3.14e-0436763GO:0086010
GeneOntologyBiologicalProcessregulation of heart contraction

ADCY10 THRA KCNJ2 KCNJ3 SCN10A CACNA1H

3.15e-04249766GO:0008016
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction

ADCY10 KCNJ2 SCN10A CACNA1H

3.28e-0489764GO:0055117
GeneOntologyBiologicalProcesscirculatory system process

TBC1D8 ADCY10 SLC4A8 THRA KCNJ2 KCNJ3 SCN10A CACNA1H SLC1A4 SLC2A3

3.47e-047337610GO:0003013
GeneOntologyBiologicalProcesscardiac muscle contraction

ADCY10 KCNJ2 KCNJ3 SCN10A CACNA1H

3.81e-04167765GO:0060048
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC4A8 SLC10A2 SLC12A4 SLC39A3 MS4A1 KCNJ2 KCNJ3 SCN10A CD63 CACNA1H FXYD3 CXCL11 SLC1A4 VDR

4.41e-0413747614GO:0006811
GeneOntologyBiologicalProcessregulation of cardiac muscle cell contraction

ADCY10 KCNJ2 CACNA1H

5.34e-0443763GO:0086004
GeneOntologyBiologicalProcessinorganic anion transport

SLC4A8 SLC12A4 FXYD3 SLC1A4 VDR

5.36e-04180765GO:0015698
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC4A8 SLC12A4 SLC39A3 MS4A1 KCNJ2 KCNJ3 SCN10A CD63 CACNA1H FXYD3 CXCL11

5.37e-049227611GO:0098662
GeneOntologyCellularComponentsarcolemma

DTNA KCNJ2 KCNJ3 ESR1 CACNA1H VDR

7.23e-05190776GO:0042383
GeneOntologyCellularComponentT-tubule

KCNJ2 KCNJ3 ESR1 VDR

2.07e-0479774GO:0030315
DomainScramblase

PLSCR4 PLSCR2 PLSCR1

5.94e-075743PF03803
DomainScramblase

PLSCR4 PLSCR2 PLSCR1

5.94e-075743IPR005552
Domainzf-C4

THRA ESR1 VDR

8.02e-0446743PF00105
DomainZnf_hrmn_rcpt

THRA ESR1 VDR

8.02e-0446743IPR001628
DomainNuclear_hrmn_rcpt

THRA ESR1 VDR

8.02e-0446743IPR001723
DomainNUCLEAR_REC_DBD_2

THRA ESR1 VDR

8.02e-0446743PS51030
DomainNUCLEAR_REC_DBD_1

THRA ESR1 VDR

8.02e-0446743PS00031
DomainZnF_C4

THRA ESR1 VDR

8.02e-0446743SM00399
Domain-

THRA ESR1 VDR

8.54e-04477431.10.565.10
DomainHOLI

THRA ESR1 VDR

9.09e-0448743SM00430
DomainNucl_hrmn_rcpt_lig-bd

THRA ESR1 VDR

9.09e-0448743IPR000536
DomainHormone_recep

THRA ESR1 VDR

9.09e-0448743PF00104
Domain-

THRA ESR1 VDR

1.50e-03577433.30.50.10
DomainZnf_NHR/GATA

THRA ESR1 VDR

1.58e-0358743IPR013088
DomainGRAM

TBC1D8 MTMR1

1.79e-0316742SM00568
DomainK_chnl_inward-rec_Kir_cyto

KCNJ2 KCNJ3

1.79e-0316742IPR013518
DomainIRK

KCNJ2 KCNJ3

1.79e-0316742PF01007
Domain-

KCNJ2 KCNJ3

1.79e-03167422.60.40.1400
DomainK_chnl_inward-rec_Kir

KCNJ2 KCNJ3

1.79e-0316742IPR016449
DomainARM-type_fold

ARFGEF3 GPRASP1 ZER1 CTIF HUWE1 TNPO3

2.25e-03339746IPR016024
DomainTetraspanin_CS

CD63 TSPAN3

3.10e-0321742IPR018503
DomainGRAM

TBC1D8 MTMR1

3.40e-0322742PF02893
DomainGRAM

TBC1D8 MTMR1

3.40e-0322742IPR004182
Domain-

TBC1D8 EFCAB5 DTNA SPATA21 PLS1

3.77e-032617451.10.238.10
DomainTM4_1

CD63 TSPAN3

4.73e-0326742PS00421
DomainEF-hand-dom_pair

TBC1D8 EFCAB5 DTNA SPATA21 PLS1

5.62e-03287745IPR011992
DomainTetraspanin

CD63 TSPAN3

7.11e-0332742IPR000301
DomainTetraspanin_EC2

CD63 TSPAN3

7.11e-0332742IPR008952
DomainTetraspannin

CD63 TSPAN3

7.55e-0333742PF00335
DomainTetraspanin/Peripherin

CD63 TSPAN3

7.55e-0333742IPR018499
PathwayKEGG_MEDICUS_VARIANT_ESR1_POSITIVE_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

ESR1 CCND1

1.13e-045482M48983
PathwayREACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS

THRA ESR1 VDR

1.14e-0428483MM15042
PathwayREACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS

THRA ESR1 VDR

1.41e-0430483M27323
Pubmed

Identification of three new members of the phospholipid scramblase gene family.

PLSCR4 PLSCR2 PLSCR1

4.00e-08476310930526
Pubmed

Calcium binding studies of peptides of human phospholipid scramblases 1 to 4 suggest that scramblases are new class of calcium binding proteins in the cell.

PLSCR4 PLSCR2 PLSCR1

4.00e-08476319540310
Pubmed

Distinct association of gene polymorphisms of estrogen receptor and vitamin D receptor with lumbar spondylosis in post-menopausal women.

ESR1 PTH VDR

4.00e-08476316362385
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

PLSCR4 SLC4A8 SLC12A4 DTNA ANKRD26 MTMR1 MAPK13 SLC1A4 VPS13B SLC2A3 CLDN1

4.48e-08569761130639242
Pubmed

Association of gene polymorphisms and bone density in Japanese girls.

ESR1 PTH VDR

1.00e-07576311984699
Pubmed

Association of bone metabolism regulatory factor gene polymorphisms with susceptibility to ossification of the posterior longitudinal ligament of the spine and its severity.

ESR1 PTH VDR

1.00e-07576312195069
Pubmed

Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes.

SLC10A2 CCND1 VDR

1.00e-07576317960397
Pubmed

Contribution of genotype and ethnicity to bone mineral density variation in Caucasians and Chinese: a test for five candidate genes for bone mass.

ESR1 PTH VDR

1.00e-07576316117875
Pubmed

Differentiation of Caucasians and Chinese at bone mass candidate genes: implication for ethnic difference of bone mass.

ESR1 PTH VDR

1.00e-07576312914574
Pubmed

Expression of the phospholipid scramblase (PLSCR) gene family during the acute phase response.

PLSCR4 PLSCR2 PLSCR1

2.00e-07676317590392
Pubmed

T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha.

THRA ESR1 VDR

8.34e-07976312874288
Pubmed

The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion.

THRA ESR1 VDR

1.19e-06107639653119
Pubmed

A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group.

ESR1 PTH VDR

1.63e-061176318285546
Pubmed

A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein.

THRA ESR1 VDR

2.17e-061276310866662
Pubmed

TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids.

THRA ESR1 VDR

2.82e-061376315322135
Pubmed

Differential interaction of nuclear receptors with the putative human transcriptional coactivator hTIF1.

THRA ESR1 VDR

2.82e-06137639115274
Pubmed

Relation of the estrogen receptor and vitamin D receptor polymorphisms with bone mineral density in postmenopausal Mexican-mestizo women.

ESR1 VDR

4.71e-06276224389498
Pubmed

Vitamin D and oestrogen receptor polymorphisms in developmental dysplasia of the hip and primary protrusio acetabuli--a preliminary study.

ESR1 VDR

4.71e-06276217598904
Pubmed

Cyclin D1b is aberrantly regulated in response to therapeutic challenge and promotes resistance to estrogen antagonists.

ESR1 CCND1

4.71e-06276218632615
Pubmed

Effects of vitamin D and estrogen receptor gene polymorphisms on the changes in lumbar bone mineral density with multiple pregnancies in Japanese women.

ESR1 VDR

4.71e-06276214688157
Pubmed

[Association of bone mineral density with gene polymorphisms and environmental factors in Chinese postmenopausal women].

ESR1 VDR

4.71e-06276216758971
Pubmed

[Study on the relationship between some genetic factors and peak bone mineral density in Beijing young women].

ESR1 VDR

4.71e-06276212895309
Pubmed

The role of vitamin D, estrogen, calcium sensing receptor genotypes and serum calcium in the pathogenesis of prostate cancer.

ESR1 VDR

4.71e-06276221703046
Pubmed

Differential Regulation of POC5 by ERα in Human Normal and Scoliotic Cells.

ESR1 POC5

4.71e-06276237239471
Pubmed

Evaluation of the effects of vitamin D receptor and estrogen receptor 1 gene polymorphisms on bone mineral density in postmenopausal women.

ESR1 VDR

4.71e-06276220697762
Pubmed

CDK-independent activation of estrogen receptor by cyclin D1.

ESR1 CCND1

4.71e-0627629039267
Pubmed

Interaction effects between estrogen receptor alpha and vitamin D receptor genes on age at menarche in Chinese women.

ESR1 VDR

4.71e-06276215960894
Pubmed

Vitamin D and estrogen receptor-alpha genotype and indices of bone mass and bone turnover in Danish girls.

ESR1 VDR

4.71e-06276216816928
Pubmed

Loss of cyclin D1 in concert with deregulated estrogen receptor alpha expression induces DNA damage response activation and interrupts mammary gland morphogenesis.

ESR1 CCND1

4.71e-06276218071314
Pubmed

Association between VDR and ESR1 gene polymorphisms with bone and obesity phenotypes in Chinese male nuclear families.

ESR1 VDR

4.71e-06276219960008
Pubmed

Stimulation of phosphatidylserine biosynthesis and facilitation of UV-induced apoptosis in Chinese hamster ovary cells overexpressing phospholipid scramblase 1.

PLSCR2 PLSCR1

4.71e-06276212509439
Pubmed

Evaluation of ERα and VDR gene polymorphisms in relation to bone mineral density in Turkish postmenopausal women.

ESR1 VDR

4.71e-06276222311020
Pubmed

Genetic determinants of bone mass do not relate with breast cancer risk in US white and African-American women.

ESR1 VDR

4.71e-06276216791482
Pubmed

Inhibition of Cav 3.2 calcium channels: A new target for colonic hypersensitivity associated with low-grade inflammation.

SCN10A CACNA1H

4.71e-06276230714145
Pubmed

Genetic Polymorphisms in the ESR1 and VDR Genes Do Not Correlate With Osteoporosis in Patients With Familial Dysautonomia.

ESR1 VDR

4.71e-06276228161223
Pubmed

Biphasic ER-α36-mediated estrogen signaling regulates growth of gastric cancer cells.

ESR1 CCND1

4.71e-06276225231129
Pubmed

Association of vitamin D receptor and estrogen receptor gene polymorphisms with bone mass in postmenopausal Korean women.

ESR1 VDR

4.71e-06276211355046
Pubmed

Association of vitamin D receptor and estrogen receptor-alpha gene polymorphism with peak bone mass and bone size in Chinese women.

ESR1 VDR

4.71e-06276215066214
Pubmed

Identity of a conserved motif in phospholipid scramblase that is required for Ca2+-accelerated transbilayer movement of membrane phospholipids.

PLSCR2 PLSCR1

4.71e-0627629485382
Pubmed

Possible association of combined vitamin D receptor and estrogen receptor genotypes and low bone mineral density in Jordanian postmenopausal women.

ESR1 VDR

4.71e-06276219814616
Pubmed

Genotypes and clinical aspects associated with bone mineral density in Argentine postmenopausal women.

ESR1 VDR

4.71e-06276218600402
Pubmed

Genetic Loss of IK1 Causes Adrenergic-Induced Phase 3 Early Afterdepolariz ations and Polymorphic and Bidirectional Ventricular Tachycardia.

KCNJ2 KCNJ3

4.71e-06276232931337
Pubmed

Utility of Ki67 labeling index, cyclin D1 expression, and ER-activity level in postmenopausal ER-positive and HER2-negative breast cancer with neoadjuvant chemo-endocrine therapy.

ESR1 CCND1

4.71e-06276231112577
Pubmed

The association of lumbar disc disease with vitamin-D receptor gene polymorphism.

ESR1 VDR

4.71e-06276212429765
Pubmed

Dystrobrevin alpha gene is a direct target of the vitamin D receptor in muscle.

DTNA VDR

4.71e-06276231940280
Pubmed

Association of estrogen receptor-alpha and vitamin D receptor genotypes with therapeutic response to calcium in postmenopausal Chinese women.

ESR1 VDR

4.71e-06276215569417
Pubmed

Does vitamin D supplementation of healthy Danish Caucasian girls affect bone turnover and bone mineralization?

ESR1 VDR

4.71e-06276219735754
Pubmed

N-terminal proline-rich domain is required for scrambling activity of human phospholipid scramblases.

PLSCR2 PLSCR1

4.71e-06276224648509
Pubmed

Pyruvate kinase L/R links metabolism dysfunction to neuroendocrine differentiation of prostate cancer by ZBTB10 deficiency.

PKLR ZBTB10

4.71e-06276235306527
Pubmed

A region of the muscarinic-gated atrial K+ channel critical for activation by G protein beta gamma subunits.

KCNJ2 KCNJ3

4.71e-0627627917304
Pubmed

Vitamin D and estrogen receptor gene polymorphisms and the risk of colorectal cancer in Bulgaria.

ESR1 VDR

4.71e-06276216788818
Pubmed

Genome-wide study of ER-regulated lncRNAs shows AP000439.3 may function as a key regulator of cell cycle in breast cancer.

ESR1 CCND1

4.71e-06276229048636
Pubmed

Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia.

PTH VDR

4.71e-0627629275211
Pubmed

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

ESR1 CCND1

4.71e-0627627664341
Pubmed

Vitamin D Receptor in Breast Cancer Tissues and Its Relation to Estrogen Receptor Alpha (ER-α) Gene Expression and Serum 25-hydroxyvitamin D Levels in Egyptian Breast Cancer Patients: A Case-control Study.

ESR1 VDR

4.71e-06276230833174
Pubmed

Genotypes of vitamin D and estrogen receptors in pre and perimenopausal women from Córdoba, Argentina.

ESR1 VDR

4.71e-06276217408018
Pubmed

Regulation of the functional interaction between cyclin D1 and the estrogen receptor.

ESR1 CCND1

4.71e-06276211073968
Pubmed

Association of polymorphisms in estrogen and thyroid hormone receptors with thyroid cancer risk.

THRA ESR1

4.71e-06276219519176
Pubmed

Estrogen receptor alpha and vitamin D receptor gene polymorphisms and bone mineral density: association study of healthy pre- and postmenopausal Chinese women.

ESR1 VDR

4.71e-06276212927786
Pubmed

Association of oestrogen receptor gene polymorphism with the long-term results of rotational acetabular osteotomy.

ESR1 VDR

4.71e-06276219219433
Pubmed

Cyclin D1b represses breast cancer cell growth by antagonizing the action of cyclin D1a on estrogen receptor alpha-mediated transcription.

ESR1 CCND1

4.71e-06276219956831
Pubmed

Effect of vitamin D receptor and estrogen receptor gene polymorphism on the relationship between dietary calcium and bone mineral density in Japanese women.

ESR1 VDR

4.71e-06276214999525
Pubmed

Influence of vitamin D and estrogen receptor gene polymorphisms on calcium absorption: BsmI predicts a greater decrease during energy restriction.

ESR1 VDR

4.71e-06276226165414
Pubmed

Prevalence and functional significance of 25-hydroxyvitamin D deficiency and vitamin D receptor gene polymorphisms in Asian Indians.

PTH VDR

4.71e-06276216762954
Pubmed

Interaction effects between estrogen receptor alpha gene, vitamin D receptor gene, age, and sex on bone mineral density in Chinese.

ESR1 VDR

4.71e-06276214505233
Pubmed

Association of vitamin D receptor BsmI (rs1544410) gene polymorphism with the intact parathyroid hormone (iPTH) level among patients with end-stage renal disease.

PTH VDR

4.71e-06276225007156
Pubmed

Polymorphisms in vitamin D receptor and parathyroid hormone genes in the development and progression of obstructive sleep apnea in Asian Indians.

PTH VDR

4.71e-06276233895557
Pubmed

Parathyroid hormone gene variant and calcific aortic stenosis.

PTH VDR

4.71e-06276219557980
Pubmed

E3 Ubiquitin Ligase ASB14 Inhibits Cardiomyocyte Proliferation by Regulating MAPRE2 Ubiquitination.

ASB14 MAPRE2

4.71e-06276238319584
Pubmed

The bone mass density in postmenopausal women using hormonal replacement therapy in relation to polymorphism in vitamin D receptor and estrogen receptor genes.

ESR1 VDR

4.71e-06276219903038
Pubmed

Vitamin D receptor, oestrogen receptor-alpha gene and interleukin-1 receptor antagonist gene polymorphisms in Hungarian patients with primary biliary cirrhosis.

ESR1 VDR

4.71e-06276212169981
Pubmed

Interaction between vitamin D receptor genotype and estrogen receptor alpha genotype influences vertebral fracture risk.

ESR1 VDR

4.71e-06276212915669
Pubmed

Genomic and metabolomic patterns segregate with responses to calcium and vitamin D supplementation.

ESR1 VDR

4.71e-06276220727239
Pubmed

Phospholipid scramblase expression in the pregnant mouse uterus in LPS-induced preterm delivery.

PLSCR4 PLSCR1

4.71e-06276222598484
Pubmed

The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor Function.

SCN10A CACNA1H

4.71e-06276225600872
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

MXRA5 MYO6 RBL2 PSMB3 SCN10A PKLR CD63 HUWE1 PLS1 PLSCR1 TSPAN3

1.27e-051016761119056867
Pubmed

Oestrogen receptor alpha genotype, and interactions between vitamin D receptor and transforming growth factor-beta1 genotypes are associated with quantitative calcaneal ultrasound in postmenopausal women.

ESR1 VDR

1.41e-05376214725686
Pubmed

Functional cooperation between CCAAT/enhancer-binding proteins and the vitamin D receptor in regulation of 25-hydroxyvitamin D3 24-hydroxylase.

PTH VDR

1.41e-05376215601867
Pubmed

Analysis of polymorphisms of the vitamin D receptor, estrogen receptor, and collagen Ialpha1 genes and their relationship with height in children with bone cancer.

ESR1 VDR

1.41e-05376214528100
Pubmed

Tests of linkage and/or association of genes for vitamin D receptor, osteocalcin, and parathyroid hormone with bone mineral density.

PTH VDR

1.41e-05376211918225
Pubmed

MicroRNA-27a Indirectly Regulates Estrogen Receptor {alpha} Expression and Hormone Responsiveness in MCF-7 Breast Cancer Cells.

ESR1 ZBTB10

1.41e-05376220382698
Pubmed

The actin-binding protein, actinin alpha 4 (ACTN4), is a nuclear receptor coactivator that promotes proliferation of MCF-7 breast cancer cells.

ESR1 VDR

1.41e-05376221078666
Pubmed

Estrogen receptor gene polymorphisms and the genetics of osteoporosis: a HuGE review.

ESR1 VDR

1.41e-05376215692074
Pubmed

Genetic control of bone density and turnover: role of the collagen 1alpha1, estrogen receptor, and vitamin D receptor genes.

ESR1 VDR

1.41e-05376211316004
Pubmed

Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity.

ESR1 CCND1

1.41e-05376216061635
Pubmed

Cloning and characterization of a novel WD-40 repeat protein that dramatically accelerates osteoblastic differentiation.

ARFGEF3 PTH

1.41e-05376211551928
Pubmed

Genetic predispositions and the short- and long-term effects of hormonal therapy on bone mineral density in girls with functional hypothalamic amenorrhoea.

ESR1 VDR

1.41e-05376223338998
Pubmed

Claudin-1 expression decreases with increasing pathological grade in actinic keratosis and may be a marker of high-risk actinic keratosis.

CLDN1 VDR

1.41e-05376230315595
Pubmed

Feedback control of the CXCR7/CXCL11 chemokine axis by estrogen receptor α in ovarian cancer.

ESR1 CXCL11

1.41e-05376230051594
Pubmed

Genetic and environmental determinants of peak bone mass in young men and women.

ESR1 VDR

1.41e-05376212096841
Pubmed

Use of genetically modified mice to examine the skeletal anabolic activity of vitamin D.

PTH VDR

1.41e-05376217254773
Pubmed

Estrogens and progesterone promote persistent CCND1 gene activation during G1 by inducing transcriptional derepression via c-Jun/c-Fos/estrogen receptor (progesterone receptor) complex assembly to a distal regulatory element and recruitment of cyclin D1 to its own gene promoter.

ESR1 CCND1

1.41e-05376215282324
Pubmed

In vitro and in vivo roles of glucocorticoid and vitamin D receptors in the control of neonatal cardiomyocyte proliferative potential.

THRA VDR

1.41e-05376232289320
Pubmed

Opposing action of estrogen receptors alpha and beta on cyclin D1 gene expression.

ESR1 CCND1

1.41e-05376211986316
Pubmed

Association of bone metabolism related genes polymorphisms with the effect of raloxifene hydrochloride on bone mineral density and bone turnover markers in postmenopausal women with osteoporosis.

ESR1 VDR

1.41e-05376216604479
Pubmed

Human TAF(II)55 interacts with the vitamin D(3) and thyroid hormone receptors and with derivatives of the retinoid X receptor that have altered transactivation properties.

THRA VDR

1.41e-05376210409738
Pubmed

[High expression of cyclin D1 is correlated with the expression of estrogen receptor and good prognosis in breast cancer].

ESR1 CCND1

1.41e-05376226728382
Pubmed

[The relativity between chronic periodontitis and the genetic polymorphisms of vitamin D receptor and estrogen receptor].

ESR1 VDR

1.41e-05376218846948
Pubmed

Influence of genetic polymorphisms on bone disease of preterm infants.

ESR1 VDR

1.41e-05376216988190
Pubmed

Genetic effects of estrogen receptor alpha and collagen IA1 genes on the relationships of parathyroid hormone and 25 hydroxyvitamin D with bone mineral density in Caucasian women.

ESR1 PTH

1.41e-05376214506618
InteractionLGALS9C interactions

SLC12A4 CD63 PLSCR1 TSPAN3

7.62e-0635734int:LGALS9C
CytobandEnsembl 112 genes in cytogenetic band chr3q24

PLSCR4 PLSCR2 PLSCR1

6.97e-0547773chr3q24
Cytoband3q24

PLSCR4 PLSCR2

1.25e-03317723q24
Cytoband22q12.1

TPST2 TFIP11

1.33e-033277222q12.1
GeneFamilyPhospholipid scramblases

PLSCR4 PLSCR2 PLSCR1

3.29e-075593954
GeneFamilyNuclear hormone receptors

THRA ESR1 VDR

5.47e-044959371
GeneFamilyPotassium voltage-gated channel subfamily J

KCNJ2 KCNJ3

1.22e-0316592276
GeneFamilySolute carriers

SLC4A8 SLC10A2 SLC12A4 SLC39A3 SLC1A4 SLC2A3

1.78e-03395596752
GeneFamilyCD molecules|Tetraspanins

CD63 TSPAN3

5.18e-0333592768
CoexpressionGSE42724_MEMORY_BCELL_VS_PLASMABLAST_UP

SLC4A8 ZBTB10 CXCL11 PLSCR1 DENND3 TSPAN3 VDR

1.68e-06199757M9786
CoexpressionSTEIN_ESRRA_TARGETS_DN

MSH6 MYO6 PLS1 CLDN1 VDR

1.29e-05105755M18160
CoexpressionHOSHIDA_LIVER_CANCER_SURVIVAL_DN

MSH6 KCNJ3 PSMB3 PKLR ZER1

1.85e-05113755M5451
CoexpressionRUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP

CD63 CCND1 MAPRE2 SLC1A4 PLSCR1 DENND3 TSPAN3 SLC2A3

2.30e-05411758M19971
CoexpressionLEE_LIVER_CANCER_MYC_TGFA_UP

CD63 CCND1 SLC1A4 PLSCR1

2.85e-0561754M3432
CoexpressionGARCIA_PINERES_PBMC_HPV_16_L1_VLP_AGE_18_25YO_2MO_UP

PREP KCNJ2 ESR1 CXCL11 SLC1A4 SLC2A3 VDR

3.99e-05324757M41138
CoexpressionDELACROIX_RAR_TARGETS_DN

CCND1 PLSCR2 PLSCR1

5.58e-0526753MM950
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4

GPRASP1 SLC4A8 SLC10A2 THRA TTLL3 KIAA0825 DTNA RBL2 MTMR1 CACNA1H FXYD3

2.24e-057217011Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K4
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3

GPRASP1 SLC4A8 SLC10A2 THRA TTLL3 KIAA0825 DTNA RBL2 MED12L MTMR1 CACNA1H

2.51e-057307011Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

SLC10A2 THRA DTNA MTMR1 ZER1 CACNA1H CCND1

1.26e-04339707Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K3
CoexpressionAtlasMyeloid Cells, DC.8-4-11b+.SLN, CD11b-FITC CD4-PE CD11c-eFluor780 CD8a-eFluor450 C, Lymph Node, avg-1

TBC1D8 SLC4A8 CD63 TSPAN3

1.29e-0478704GSM854287_100
CoexpressionAtlasMyeloid Cells, DC.IIhilang-103-11b+.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b+, Lymph Node, avg-3

TBC1D8 SLC4A8 CD63 TSPAN3

1.29e-0478704GSM538274_100
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2

SLC4A8 SLC10A2 THRA TTLL3 KIAA0825 DTNA RBL2 MED12L MTMR1 CACNA1H

1.61e-047477010Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K2
CoexpressionAtlasMyeloid Cells, DC.8-4-11b+.SLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-2

TBC1D8 SLC4A8 CD63 TSPAN3

1.64e-0483704GSM854285_100
CoexpressionAtlasMyeloid Cells, DC.8-4-11b-.MLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-3

TBC1D8 SLC4A8 CD63 TSPAN3

1.96e-0487704GSM605836_100
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MED12L ACKR4 MAPK13 FXYD3 CLDN1 VDR

7.54e-071827769174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO6 CCND1 PLSCR2 MAPK13 FXYD3 VDR

1.09e-061947760ef63abcfd057079a9a6f8b27404ff521d44845d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO6 CCND1 FXYD3 PLS1 TSPAN3 CLDN1

1.31e-06200776f386a86b127433cbac306950443355bd723080ff
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO6 CCND1 FXYD3 PLS1 TSPAN3 CLDN1

1.31e-06200776b75154417c215b8853186bff46d624ebd387ac4f
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TPST2 RBL2 CTIF PLS1 TNPO3

1.09e-0516877594cded2e953c0970bf2f3dbe0ce46bd77a5ed8c7
ToppCelldroplet-Thymus-nan-21m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MS4A1 SPATA21 ACKR4 CXCL11 PLSCR1

1.18e-051717758bed33f61f7d12a1ac4fba33f730d839f5ee7bef
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DTNA MED12L CCND1 CLDN1 VDR

1.29e-0517477546bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCellfacs-Lung-EPCAM-24m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 TES SLC4A8 CD63 VDR

1.48e-0517977551872338e54c5f3e42ca9f1c4cf1e8b0cb84afcc
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 TES SLC4A8 CD63 VDR

1.48e-051797751b979e0203a2ddfe98bf6c2c80c4af1ba437a80f
ToppCellfacs|World / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES MAPK13 PLS1 PLSCR1 TSPAN3

1.60e-0518277508f775135b451be709f5fc8e1cbcf63425794a2e
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TBC1D8 TES SLC4A8 CD63 VDR

1.73e-0518577519fa853f6f746ccf232a343b3c9c7a5e55800409
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACKR4 MAPK13 FXYD3 CLDN1 VDR

1.92e-051897756f0fc5271a7d3682f145e734abc3be6473dda2e2
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 CACNA1H FXYD3 CXCL11 SLC1A4

1.92e-051897755a0fd34928117f162c83ca1b068aa8f7069a6765
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACKR4 MAPK13 FXYD3 CLDN1 VDR

1.92e-051897753b9ce8964b16cb2200d30cbb0bfc711dcad2380e
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACKR4 MAPK13 FXYD3 CLDN1 VDR

1.92e-0518977538acb307907fde68b992057714448c1561d69ee3
ToppCelldroplet-Skin-nan-21m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A8 SLC12A4 CCND1 ACKR4 FXYD3

1.97e-05190775c1bfc1960a3df49c0f459454a7363804c32418ee
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 KCNJ3 MAPK13 FXYD3 VWDE

2.02e-0519177519832ddd559a353e1618fe853d79e3edfec6dcda
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

RESF1 ADAMTS9 CD63 ACKR4 VDR

2.02e-0519177578ad7c555409ce1391bce406bc0f3ef575329ece
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 KCNJ3 CACNA1H FXYD3 VWDE

2.12e-051937758603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

PLSCR4 TPST2 ADAMTS9 AK5 PLSCR1

2.12e-051937752531266bc57339d4e2b22a88817008e32b8c1598
ToppCell10x3'2.3-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TPST2 SLC39A3 MED12L MAPRE2 SLC2A3

2.12e-051937753d4411b3c1cb160dec5db29f0c126d8827dfe185
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RESF1 MYO6 CCND1 PLSCR2 CLDN1

2.17e-05194775550e61a40be2baa59520aaf5912bb99ad094ba15
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KCNJ2 KCNJ3 DENND3 SLC2A3 CLEC2B

2.17e-05194775607b5d194ba56efa9b106f10f89368fc103712a0
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KCNJ2 KCNJ3 DENND3 SLC2A3 CLEC2B

2.17e-05194775f5367072b259ae170cf0df3d4d871ab41be29d29
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids|BALF-PFMC / Compartment, severity and other cell annotations on 10x 3' data (130k)

CCND1 FXYD3 CXCL11 PLS1 CLDN1

2.34e-05197775495bfdb40b640591fbbaaa99f419bb6468cef405
ToppCelldroplet-Mammary_Gland-nan-18m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO6 CCND1 PLSCR2 MAPK13 FXYD3

2.34e-05197775ed3a37f532741764060d297a560eeeeec279d9c4
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

TBC1D8 SLC12A4 MS4A1 MYO6 MAPK13

2.34e-051977758545baf923ddf84c5ce9414a36d810603be52401
ToppCellT/NK_cells-NKT_cell|T/NK_cells / Lineage and Cell class

TPST2 MYO6 CD63 DENND3 CLEC2B

2.34e-0519777510702e61b510bfc7f54047ab3d8c700451a662b2
ToppCellBAL-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

CD63 CXCL11 PLSCR1 SLC2A3 CLEC2B

2.46e-051997759f5750212b887f92761ade33fc6e108cd5275297
ToppCellcritical-Epithelial|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ARFGEF3 MYO6 FXYD3 PLS1 TSPAN3

2.46e-05199775bbb44e2a52f102a6d891ead6c06d6c07221abd33
ToppCell15-Trachea-Epithelial|Trachea / Age, Tissue, Lineage and Cell class

ARFGEF3 MYO6 CD63 FXYD3 TSPAN3

2.46e-05199775e0099aa95cf3ec08d7688cc97f4b917fce65a7a3
ToppCellPSB-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARFGEF3 MYO6 FXYD3 PLS1 TSPAN3

2.46e-0519977558dcb0eedafa8629585dc99e53147e2287f49689
ToppCellNS-critical-d_07-13-Epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARFGEF3 MYO6 FXYD3 PLS1 TSPAN3

2.46e-05199775b88a81cd2a89f4d27100c96ae4324dcee68daf83
ToppCelltumor_Lung-Epithelial_cells|tumor_Lung / Location, Cell class and cell subclass

ARFGEF3 MYO6 CCND1 FXYD3 TSPAN3

2.46e-0519977556b3f6c8b561d60780d91daf6b44a9dcf616e599
ToppCellNS-moderate-d_16-33-Epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARFGEF3 MYO6 FXYD3 PLS1 TSPAN3

2.46e-05199775aa2b51940115c22768c0d7493b4b60d41df3f376
ToppCellNS-control-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARFGEF3 MYO6 FXYD3 TSPAN3 CLDN1

2.52e-05200775d014959891893b6d3854a471fba1dc50c6625a0a
ToppCellSevere-Epithelial-Epithelial-|Severe / Condition, Lineage, Cell class and cell subclass

ARFGEF3 MYO6 FXYD3 PLS1 CLDN1

2.52e-052007758669ce08f93eefb8ac970e30cdc4b1f908023c54
ToppCellSevere-Epithelial|Severe / Condition, Lineage, Cell class and cell subclass

ARFGEF3 MYO6 FXYD3 PLS1 CLDN1

2.52e-052007756ead9db88568bb829d564a6d8e85f71fd765bac0
ToppCellSevere-Epithelial-Epithelial|Severe / Condition, Lineage, Cell class and cell subclass

ARFGEF3 MYO6 FXYD3 PLS1 CLDN1

2.52e-052007753bd1ce2793651c9badd69f011d2531183594e5f4
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADCY10 KCNJ2 ESR1 KCTD4

8.11e-05132774ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar-Club_cell|E18.5-samps / Age Group, Lineage, Cell class and subclass

SPATA21 MED12L ASB14 MAPK13

1.30e-0414977482edfecb7981d8c336cf9da7aa7e2b3f7a017a3f
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar|E18.5-samps / Age Group, Lineage, Cell class and subclass

SPATA21 MED12L ASB14 MAPK13

1.30e-0414977414a01ae540db8a350ea26a350b2e6ce6c07639d9
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MXRA5 CCND1 FXYD3 CLDN1

1.33e-04150774aa11579a57d671a55e64183d35c1340fda6dec14
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNJ2 MAPK13 PLS1 SLC2A3

1.36e-041517745893a51585a65f1902cf85124a5ed9f02b4eb82a
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNJ2 MAPK13 PLS1 SLC2A3

1.36e-04151774771224e0d6fccfa4225b3adccd7bc22a89a40793
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MED12L CCND1 FXYD3 CLDN1

1.43e-0415377482b77c8bae49dd63b8f10eb67df66ca71d0bb315
ToppCell(6)_Endothelial_cells-(6)_Endothelial-C_(Capillary_Aerocyte_)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

MXRA5 MYO6 DTNA CCND1

1.58e-0415777484f629b7f589ca8a1abc220fa740c4a6fdc1b579
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|368C / Donor, Lineage, Cell class and subclass (all cells)

TPST2 RBL2 PLS1 TNPO3

1.62e-04158774390b9c455ed15a6804613eecfd2776949dfba146
ToppCelldroplet-Spleen-nan-24m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 CD63 CCND1 MAPK13

1.62e-04158774e1a8dba5a88bc3ce112829c5ecb112cbbee5b078
ToppCelldroplet-Spleen-nan-24m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 CD63 CCND1 MAPK13

1.62e-0415877472e4f8ae137a7dddee0dc6236532e0711065e6af
ToppCelldroplet-Thymus-nan-21m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 CCND1 MAPK13 CLDN1

1.74e-04161774441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-neutrophil|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD63 MAPK13 PLS1 SLC2A3

1.79e-041627749c9a63adb692651ea5a52cc77b02c5ce11d0ccea
ToppCelldroplet-Lung-30m-Hematologic-myeloid-neutrophil-neutrophil|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD63 MAPK13 PLS1 SLC2A3

1.79e-041627741d29983b22f963b34e72cfd1eec328d2d7c4932f
ToppCelldroplet-Lung-21m-Hematologic-myeloid-neutrophil|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNJ2 MED12L MAPK13 SLC2A3

1.79e-04162774f24eb596653180040bfdefad9c246fc42cbfaac8
ToppCelldroplet-Lung-21m-Hematologic-myeloid-neutrophil-neutrophil|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNJ2 MED12L MAPK13 SLC2A3

1.79e-041627741a953e165b7e469815294728350ec13d27c9bd9d
ToppCelldroplet-Spleen-nan-18m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 MAPK13 SLC2A3 CLDN1

1.83e-04163774bc37c5d9f48b16096d5313657563f3ec84028c8c
ToppCelldroplet-Spleen-nan-21m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 CD63 CCND1 MAPK13

1.92e-04165774fbd84f211ad645c91b9f45a0815391606f3206ac
ToppCelldroplet-Spleen-nan-21m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 CD63 CCND1 MAPK13

1.92e-041657746fbdfacb49e627712ac999d40ae22dcb390edd3e
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TPST2 MYO6 RBL2 CLEC2B

2.05e-04168774b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCellImmune_cells-Neutrophils|Immune_cells / Lineage and Cell class

CD63 MAPK13 PLSCR1 SLC2A3

2.05e-041687743539f802fe0143da1462df0618f78f9f15143f71
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNJ2 CD63 CCND1 MAPRE2

2.10e-04169774780fb0050852626062a729dd1b82b0cf61e7e9ca
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PREP SPATA21 AK5 CLEC2B

2.10e-0416977496aafb687b34d4b59f75c24e176b0b442e864245
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCNJ2 CD63 CACNA1H CLDN1

2.15e-0417077414aa86a4f526ed6986afcb28c49225522055550c
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TBC1D8 TES CXCL11 PTH

2.15e-04170774df1a34a69ae404c56f00751a01f52359535f5469
ToppCellileum|World / shred on tissue and cell subclass

SLC10A2 RESF1 BTNL3 PLS1

2.15e-041707749f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCelldroplet-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 CD63 CCND1 CLDN1

2.20e-0417177425493a4a7b636920e2cfd984542cc500709c9dcf
ToppCelldroplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 CD63 CCND1 CLDN1

2.20e-04171774508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCellILEUM-non-inflamed-(3)_Inf._Macrophages|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KCNJ2 CXCL11 PLSCR1 CLDN1

2.30e-04173774a8db746992a915a8431ac5c155612e89c4af3cad
ToppCelldroplet-Thymus-nan-3m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 CD63 CCND1 CLDN1

2.30e-0417377463f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EFCAB5 SLC4A8 CCND1 ASB14

2.30e-04173774b6aed736d8480e3a6a5718aabd2fb79b1b75fa48
ToppCellTCGA-Brain-Primary_Tumor|TCGA-Brain / Sample_Type by Project: Shred V9

THRA SLC12A4 DTNA TSPAN3

2.30e-04173774f6ba22661e67c17d49d1058d4170ba8f36bf47f0
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 SLC4A8 CCND1 TSPAN3

2.35e-041747747be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCelldroplet-Marrow-nan-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD63 MAPK13 PLSCR1 SLC2A3

2.35e-041747744b749ac9f05776c0c56b74daca833bd0b5704299
ToppCelldroplet-Lung-nan-21m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 MED12L CCND1 CLDN1

2.35e-041747742afa5eea54b67c549c5058ece98296eee3829c11
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PREP MAPK13 FXYD3 PLS1

2.40e-041757748727252bcbc70bfa2ff72e7421df9cfe6fd4eed7
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TBC1D8 SLC4A8 CCND1 TSPAN3

2.40e-041757741b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCelldroplet-Liver-Npc-21m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TES MS4A1 ASB14 FXYD3

2.40e-04175774046e841811b22c39f80a9752f3223c1906de6f20
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DTNA ZFYVE26 PLS1 SLC2A3

2.40e-04175774bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-Tuft-related|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PREP MAPK13 FXYD3 PLS1

2.40e-04175774c083abe368e5c0dc2b0f27f375c9271a2d7ff64f
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 MED12L CCND1 PTH

2.45e-0417677474f851a398c7562dd713bc0d8d488c0037243112
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 MED12L CCND1 PTH

2.45e-0417677431b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCellfacs-Lung-EPCAM-3m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 TES CXCL11 PTH

2.50e-04177774d445167dae956e641386f84ab3ae9f47c089e09a
ToppCelldroplet-Limb_Muscle-nan-21m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL3 KIAA0825 FXYD3 CLDN1

2.50e-04177774291231b1520c135e92739e201495fe1935efa927
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D8 TES CXCL11 PTH

2.56e-041787740b456ac768e026c3ecd5a9a4f43d6f126e7685a1
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 MS4A1 DTNA ASB14

2.61e-041797744135f9e8cd8494cbc189e5210dded84659643fb8
ToppCelldroplet-Limb_Muscle-Pre-Sort|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS9 CD63 CACNA1H FXYD3

2.67e-04180774af2bafcd1b2082629de3ea336711add01565c4c4
ToppCellControl-Epithelial-Goblet|Control / Disease state, Lineage and Cell class

ARFGEF3 CCND1 FXYD3 CLDN1

2.67e-041807745293d23b8b8ea587239ffde561b70bad01632521
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KCNJ2 KCNJ3 DENND3 SLC2A3

2.67e-04180774cf7d8bf9eee2dfab2c8a6780e296b05ad42041bf
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS9 CD63 CACNA1H FXYD3

2.67e-04180774f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACKR4 MAPK13 FXYD3 VDR

2.73e-04181774a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCellfacs-Marrow-T-cells-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 CACNA1H HUWE1 PLS1

2.73e-0418177457f0cc749ae8b6a3d77e2af31f9a6e4739c57049
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACKR4 MAPK13 FXYD3 VDR

2.73e-04181774504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACKR4 MAPK13 FXYD3 VDR

2.73e-04181774a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCellfacs-Marrow-T-cells-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 CACNA1H HUWE1 PLS1

2.73e-04181774d01b35cc2fc57991a35be6a06cb7351fbabd9a11
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DTNA MED12L CLDN1 VDR

2.84e-0418377483592c332b1e82673f993d37c7f480befdc3dcda
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MED12L CCND1 CXCL11 CLDN1

2.84e-04183774bd78e5c2670e67b4363078e3ca5a5b7081d24b7e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MED12L CCND1 CXCL11 CLDN1

2.84e-04183774d1bf3abf42eb9d7facf775becf1338d1faadd647
ToppCellfacs-Brain_Non-Myeloid-Striatum_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACKR4 FXYD3 CLDN1 VDR

2.84e-04183774824ecda1219fb596a01bf5cfeee29a6daa462098
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACKR4 FXYD3 CLDN1 VDR

2.84e-0418377482b84ee065fb573688d59da97a327152a1ba294c
ToppCell(7)_Epithelial-H_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CCDC60 CCND1 FXYD3 CLDN1

2.90e-041847741f76b37c265b519171b767a52d48f31f0cdc4a3c
ComputationalOvary genes.

MXRA5 TES CCND1 MAPRE2 PLSCR1 TSPAN3 SLC2A3 CLEC2B

1.46e-04368468MODULE_1
DrugAustricine [10180-88-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A

TPST2 TES SLC4A8 RESF1 DTNA KCNJ3 ESR1 MAPRE2

2.03e-071977282812_DN
Drugsodium

SLC4A8 SLC10A2 SLC12A4 KCNJ2 KCNJ3 ESR1 SCN10A PKLR CACNA1H HUWE1 FXYD3 PTH SLC1A4 SLC2A3 CLEC2B

2.08e-079447215CID000000923
DrugDicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A

DTNA ESR1 MTMR1 ZER1 MAPK13 VPS13B CLDN1

2.12e-061877275012_UP
DrugPimozide [2062-78-4]; Up 200; 8.6uM; PC3; HT_HG-U133A

SLC4A8 DTNA ESR1 FXYD3 SLC1A4 DENND3 CLEC2B

2.70e-061947277132_UP
DrugLansoprazole [103577-45-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A

MS4A1 PKLR ZER1 CACNA1H CTIF SLC1A4 CLEC2B

2.79e-061957273529_UP
DrugPronethalol hydrochloride [51-02-5]; Up 200; 15uM; MCF7; HT_HG-U133A

DTNA RBL2 KCNJ3 ESR1 CACNA1H MAPRE2 VPS13B

3.09e-061987277322_UP
Drugtetraethylenepentamine pentahydrochloride; Up 200; 100uM; MCF7; HG-U133A

TPST2 KLHL9 RBL2 ANKRD26 HUWE1 DENND3 TSPAN3

3.19e-06199727406_UP
DrugD-tryptophan methyl ester

THRA PLS1 VDR

4.91e-0611723CID000077980
Drug4-epidoxorubicin

MSH6 THRA MS4A1 RBL2 ESR1 PSMB3 PKLR CCND1 HUWE1 MAPK13 PTH CLDN1

6.20e-067887212CID000001690
Drugvitamin D3 analog

ESR1 CCND1 PTH VDR

8.52e-0641724CID006438384
DrugEB1213

PTH VDR

9.86e-062722CID006439508
DrugAC1L4NFJ

TES ESR1

9.86e-062722CID000160328
DrugAC1L3BVK

PTH VDR

9.86e-062722CID000086590
Drug3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid

ESR1 CCND1

9.86e-062722ctd:C087550
Drugbis(4-oxyphenyl)sulfide

THRA ESR1

9.86e-062722ctd:C069693
DrugK-Cl

TES SLC12A4 MYO6 KCNJ2 KCNJ3 ESR1 MAPK13 PTH CLEC2B VDR

1.14e-055677210CID000004873
Drugthioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

TBC1D8 DTNA ESR1 ZER1 SLC1A4 TNPO3

1.76e-051727266989_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A

KCNJ2 ZER1 MAPRE2 SLC1A4 DENND3 CLDN1

1.88e-051747267136_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A

PLSCR4 TPST2 KCNJ2 MAPRE2 DENND3 CLDN1

2.07e-051777263993_UP
Drug2-methylene-19-nor-(20S)-1 alpha-hydroxy-bishomopregnacalciferol

PTH VDR

2.95e-053722ctd:C521167
Drugtorachrysone

PREP ESR1

2.95e-053722CID005321977
Drug1,25-dihydroxy-16-ene-vitamin D3

PTH VDR

2.95e-053722ctd:C087630
Drug1 alpha-hydroxyergocalciferol

PTH VDR

2.95e-053722ctd:C042533
DrugP-312

RBL2 CCND1

2.95e-053722CID000199977
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

DTNA ESR1 ANKRD26 ZER1 MAPK13 VDR

3.00e-051897261646_UP
DrugBenoxinate hydrochloride [5987-82-6]; Down 200; 11.6uM; MCF7; HT_HG-U133A

KLHL9 THRA KCNJ3 ESR1 SCN10A MTMR1

3.09e-051907264115_DN
Drugradicicol; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

MSH6 RBL2 ESR1 ANKRD26 ZER1 VDR

3.09e-05190726836_DN
DrugFlutamide [13311-84-7]; Down 200; 14.4uM; PC3; HT_HG-U133A

DTNA ESR1 CTIF MAPRE2 SLC1A4 DENND3

3.18e-051917263803_DN
DrugCimetidine [51481-61-9]; Down 200; 15.8uM; MCF7; HT_HG-U133A

GPRASP1 MS4A1 ESR1 SCN10A ANKRD26 VPS13B

3.27e-051927264144_DN
DrugSTOCK1N-28457; Down 200; 20uM; MCF7; HT_HG-U133A

DTNA KCNJ3 ESR1 ANKRD26 MTMR1 ZER1

3.37e-051937266869_DN
DrugHecogenin [467-55-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A

THRA ESR1 SCN10A ZER1 MAPK13 CLDN1

3.57e-051957267175_UP
Drugcox-2 inhibitor I; Up 200; 10uM; MCF7; HG-U133A

TPST2 DTNA RBL2 ESR1 CACNA1H DENND3

3.57e-05195726207_UP
Drugikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA

THRA DTNA ESR1 CACNA1H CTIF CLDN1

3.67e-05196726918_UP
Drug6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; MCF7; HT_HG-U133A

KCNJ3 ESR1 SCN10A CACNA1H CTIF VDR

3.67e-051967264833_UP
DrugBupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; PC3; HT_HG-U133A

DTNA ESR1 PKLR ZER1 SLC1A4 SLC2A3

3.67e-051967265112_UP
DrugDiphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A

GPRASP1 TES ESR1 MTMR1 ZER1 ZFYVE26

3.67e-051967261708_UP
Drugalpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A

BTNL3 AK5 ESR1 ZER1 HUWE1 VPS13B

3.67e-051967266169_UP
DrugEstriol [50-27-1]; Up 200; 13.8uM; PC3; HT_HG-U133A

THRA KCNJ3 SCN10A ANKRD26 CTIF HUWE1

3.78e-051977265866_UP
DrugMometasone furoate [83919-23-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A

DTNA ESR1 SCN10A MAPK13 MAPRE2 SLC1A4

3.78e-051977265541_UP
DrugAjmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; PC3; HT_HG-U133A

THRA DTNA KCNJ2 ESR1 ZER1 MAPRE2

3.78e-051977266360_UP
DrugProcyclidine hydrochloride [1508-76-5]; Down 200; 12.4uM; PC3; HT_HG-U133A

THRA DTNA AK5 ZER1 CLDN1 VDR

3.78e-051977264233_DN
DrugMoxonidine [75438-57-2]; Up 200; 16.6uM; MCF7; HT_HG-U133A

DTNA SCN10A ZER1 CACNA1H SLC1A4 VPS13B

3.78e-051977267343_UP
Drugsodium 4-phenylbutyrate; Up 200; 1000uM; MCF7; HG-U133A

TPST2 KLHL9 RBL2 ANKRD26 ZFYVE26 TSPAN3

3.78e-05197726407_UP
DrugOrphenadrine hydrochloride [341-69-5]; Up 200; 13uM; HL60; HT_HG-U133A

ADCY10 MYO6 ANKRD26 CCND1 MAPK13 VDR

3.78e-051977262356_UP
DrugAztreonam [78110-38-0]; Up 200; 9.2uM; PC3; HT_HG-U133A

SLC10A2 RBL2 ESR1 MTMR1 ZER1 SLC1A4

3.89e-051987262118_UP
DrugChlorambucil [305-03-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A

PLSCR4 BTNL3 DTNA CACNA1H CTIF PLSCR2

3.89e-051987264345_UP
DrugPizotifen malate [5189-11-7]; Up 200; 9.4uM; HL60; HT_HG-U133A

THRA BTNL3 ADAMTS9 ESR1 ZER1 MAPK13

3.89e-051987263134_UP
DrugCyclacillin [3485-14-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A

THRA DTNA ZER1 CACNA1H CTIF VDR

3.89e-051987263882_DN
DrugLevocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; MCF7; HT_HG-U133A

SLC12A4 DTNA ZER1 CACNA1H CTIF DENND3

3.89e-051987263509_UP
DrugHyoscyamine (L) [101-31-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A

ADCY10 GPRASP1 MS4A1 ESR1 PLSCR2 HUWE1

3.89e-051987265524_UP
Drug17-AAG; Down 200; 0.1uM; MCF7; HG-U133A

MS4A1 RBL2 KCNJ2 KCNJ3 ESR1 VDR

3.89e-05198726221_DN
DrugParoxetine maleate [64006-44-6]; Up 200; 1uM; MCF7; HT_HG-U133A

MS4A1 DTNA ZER1 CACNA1H CTIF SLC2A3

3.89e-051987264378_UP
DrugSulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; PC3; HT_HG-U133A

DTNA KCNJ2 AK5 ESR1 ANKRD26 ZER1

4.00e-051997266349_UP
DrugKarakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A

SLC10A2 DTNA AK5 ANKRD26 SLC1A4 CLDN1

4.00e-051997263741_DN
Drugrapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; MCF7; HT_HG-U133A

THRA DTNA ESR1 SCN10A CACNA1H HUWE1

4.00e-051997265927_UP
DrugGly-His-Lys acetate salt; Up 200; 1uM; MCF7; HT_HG-U133A

TBC1D8 KCNJ3 ZFYVE26 TNPO3 PLSCR1 TSPAN3

4.00e-051997266575_UP
DrugSC-58125; Down 200; 10uM; MCF7; HG-U133A

DTNA RBL2 ZBTB10 DENND3 CLEC2B VDR

4.00e-05199726254_DN
Drugtetraethylenepentamine pentahydrochloride; Up 200; 10uM; MCF7; HG-U133A

TPST2 KLHL9 RBL2 HUWE1 DENND3 TSPAN3

4.00e-05199726405_UP
DrugMerbromin [129-16-8]; Down 200; 5uM; HL60; HT_HG-U133A

BTNL3 SCN10A ZER1 CTIF MAPK13 VDR

4.00e-051997262577_DN
Drugazathioprine, USP; Down 200; 100uM; MCF7; HG-U133A

TPST2 SLC12A4 MYO6 CYP3A43 VPS13B VDR

4.11e-05200726338_DN
DrugMeglumine [6284-40-8]; Up 200; 20.4uM; HL60; HT_HG-U133A

MYO6 KCNJ2 AK5 ESR1 FXYD3 VPS13B

4.11e-052007263068_UP
Drugmobs

TES PTH VDR

4.47e-0522723CID003674064
Drugtemsirolimus

THRA ESR1 CCND1

5.85e-0524723ctd:C401859
DrugN-(2-hydroxypropyl)methacrylamide

PKLR CD63 CCND1

5.85e-0524723CID000038622
DrugAC1NS4C8

PTH VDR

5.89e-054722CID000003070
Drug2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol

ESR1 CCND1

5.89e-054722ctd:C439584
DrugAC1L1VK9

ESR1 CCND1

5.89e-054722CID000036323
Drug1,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3

PTH VDR

5.89e-054722ctd:C408047
Drug2,2',4,4',5-brominated diphenyl ether

THRA ESR1 CCND1

7.48e-0526723ctd:C477694
Drugalfacalcidol

SLC10A2 PTH VDR

7.48e-0526723ctd:C008088
DrugBarium

SLC12A4 KCNJ2 KCNJ3 CACNA1H

8.04e-0572724ctd:D001464
Drugparaben

ESR1 SCN10A PLS1

9.39e-0528723CID000007175
DrugPD98059

RBL2 ESR1 CCND1 MAPK13 PTH VDR

9.58e-05233726CID000004713
Drugcholylsarcosine

SLC10A2 VDR

9.80e-055722CID000125082
DrugAC1O5R3Z

PTH VDR

9.80e-055722CID006439163
Drug[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[4-(3-oxobutyl)phenoxy]oxan-3-yl] 3,4,5-trihydroxybenzoate

PREP ESR1

9.80e-055722CID010390322
DrugDB08594

SLC10A2 CCND1

9.80e-055722CID005289428
DrugAC1NR2XO

PTH VDR

9.80e-055722CID005283746
DrugAC1MHEDL

FXYD3 CXCL11 PTH VDR

1.10e-0478724CID003002890
DrugPhosphorus

DTNA MAPK13 PTH VDR

1.21e-0480724ctd:D010758
DrugButyrophenones

ESR1 CCND1

1.47e-046722ctd:D002090
Drug4-((4-hydroxyphenylimino)methylbenzene-1,2-diol

ESR1 CCND1

1.47e-046722ctd:C000593866
Drugtegaserod

THRA ESR1

1.47e-046722ctd:C105050
Drugalendronate

NEK8 ESR1 PTH VDR

1.91e-0490724CID000002088
DrugVanadates

PLSCR4 ARFGEF3 TES SLC12A4 ESR1 PSMB3 KCTD4 MED12L ZBTB10 MTMR1 PLSCR1 SLC2A3 VDR

1.99e-0413027213ctd:D014638
DrugAC1L9MD8

ESR1 CCND1

2.05e-047722CID000448803
DrugDIBA-1

RBL2 ESR1

2.05e-047722ctd:C100805
Drug4-fluorobenzoyl-TN-14003

ESR1 CCND1

2.05e-047722ctd:C477728
Drugbptc

PTH VDR

2.05e-047722CID000167153
Drugmaxacalcitol

PTH VDR

2.05e-047722ctd:C051883
Druglacidipine

ESR1 VDR

2.05e-047722ctd:C060285
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA

KCNJ3 ESR1 MTMR1 CCND1 FXYD3

2.10e-041717251000_DN
DrugN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide

KCNJ2 ESR1 CCND1 PTH SLC2A3

2.22e-04173725ctd:C063509
Drugbeta Carotene

PLSCR4 CYP3A43 ESR1 CCND1 PLSCR1

2.34e-04175725ctd:D019207
DrugZidovudine

SLC12A4 RBL2 ESR1 CCND1 SLC1A4 PLSCR1 SLC2A3 VDR

2.36e-04521728ctd:D015215
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A

PLSCR4 KCNJ2 MAPRE2 DENND3 CLDN1

2.40e-041767254565_UP
DrugChlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; MCF7; HT_HG-U133A

TES DTNA ESR1 ZER1 SLC1A4

2.40e-041767255291_UP
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

DTNA KCNJ3 ESR1 MTMR1 CCND1

2.40e-041767251535_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

KCNJ3 ESR1 MTMR1 CCND1 MAPK13

2.40e-041767253312_DN
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A

PLSCR4 TPST2 KCNJ2 ZER1 DENND3

2.46e-041777255745_UP
DiseaseRickets

PTH VDR

3.51e-054722C0035579
Diseasesecondary hyperparathyroidism (biomarker_via_orthology)

PTH VDR

3.51e-054722DOID:12466 (biomarker_via_orthology)
Diseasemale breast carcinoma

ESR1 CCND1

1.63e-048722EFO_0006861
DiseaseShortened QT interval

KCNJ2 SCN10A

3.18e-0411722C0151879
Diseaseleukemia

MSH6 ESR1 CCND1

3.34e-0455723C0023418
DiseaseChronic Lymphocytic Leukemia

RBL2 CCND1 VDR

3.34e-0455723C0023434
DiseaseEndometrial Neoplasms

MSH6 ESR1 CCND1

3.90e-0458723C0014170
DiseaseMalignant neoplasm of liver

SPATA21 ESR1 CCND1 PLS1

4.10e-04142724C0345904
DiseaseLiver neoplasms

SPATA21 ESR1 CCND1 PLS1

4.10e-04142724C0023903
Diseasetaurolithocholate 3-sulfate measurement

SLC10A2 ESR1

4.50e-0413722EFO_0021036
DiseaseT wave morphology measurement

PREP SCN10A

5.24e-0414722EFO_0008398
DiseaseEndometrial Carcinoma

MSH6 ESR1 CCND1

7.36e-0472723C0476089
DiseaseUremia

PTH VDR

7.80e-0417722C0041948
Diseasesquamous cell carcinoma (is_implicated_in)

CCND1 VDR

8.76e-0418722DOID:1749 (is_implicated_in)
Diseaseosteoporosis (implicated_via_orthology)

PTH VDR

9.77e-0419722DOID:11476 (implicated_via_orthology)
DiseasePseudopelade

CLDN1 VDR

9.77e-0419722C0086873
DiseaseBrugada syndrome

SCN10A MAPRE2

9.77e-0419722MONDO_0015263
DiseaseMalignant neoplasm of breast

MSH6 SPATA21 ESR1 ZFYVE26 CCND1 CTIF VPS13B CLDN1 VDR

1.18e-031074729C0006142
Diseasevitiligo (is_implicated_in)

ESR1 VDR

1.20e-0321722DOID:12306 (is_implicated_in)
Diseaseosteoporosis (biomarker_via_orthology)

ESR1 PTH

1.31e-0322722DOID:11476 (biomarker_via_orthology)
Diseaseatopic dermatitis (is_implicated_in)

CLDN1 VDR

1.84e-0326722DOID:3310 (is_implicated_in)
Diseaseobesity (implicated_via_orthology)

ADAMTS9 ESR1 MED12L ANKRD26

1.91e-03215724DOID:9970 (implicated_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of ovary

MSH6 ESR1

2.28e-0329722C0496920

Protein segments in the cluster

PeptideGeneStartEntry
LKRCVDIGMMKEFIL

VDR

81

P11473
GCEALVVKKLQEIMM

TSPAN3

196

O60637
ALCGVVMGMIIVFFK

BTNL3

246

Q6UXE8
AAKLCDKMALFMVEG

CTIF

431

O43310
LLGATCMFVASKMKE

CCND1

101

P24385
EIMEMLLRKGKIFCL

ASB14

231

A6NK59
CFNMGQIVLAKKMLR

ADCY10

1141

Q96PN6
KNFMLLIEQLGMECK

ANKRD26

706

Q9UPS8
CLVKGKMIMNSLSLF

MS4A1

111

P11836
FKVGTAKVNCMVMAD

DENND3

941

A2RUS2
VAKVFNKMACVLARM

GKN3P

71

P0CG01
NKMACVLARMDKAVF

GKN3P

76

P0CG01
EAGFCLQDKMEILMK

CCDC60

396

Q8IWA6
IKAIVKDVMYICPFM

MTMR1

106

Q13613
VMAMKGKNCVAIAAD

PSMB3

11

P49720
IDAFIIGAVMAKMAK

KCNJ2

171

P63252
LLMCAIYVMAKVTKE

RBL2

891

Q08999
MKALIQMLEICIGFV

ACKR4

196

Q9NPB9
MAVEGGMKCVKFLLY

CD63

1

P08962
MKKAFMRGVCALNLE

POC5

351

Q8NA72
IEVGAVFAVLKAIMM

MED12L

1171

Q86YW9
VFAVLKAIMMLGDAK

MED12L

1176

Q86YW9
EKLGLICMCLKSIMG

KIAA0825

1046

Q8IV33
MGGFMEDLRKCKIIF

AK5

366

Q9Y6K8
KGMMAGAEKLVECLL

DDX58

146

O95786
VEVKPKMVMTVFACL

PLS1

606

Q14651
KMVMTVFACLMGKGL

PLS1

611

Q14651
DVKMKAVMIGACFLI

PLSCR1

286

O15162
RDLDVKMKAVMIGAC

PLSCR2

271

Q9NRY7
KMKAVMIGACFLIDY

PLSCR2

276

Q9NRY7
DVKMKAMIFGACFLI

PLSCR4

301

Q9NRQ2
KCVEGMVEIFDMLLA

ESR1

416

P03372
PLKVFMDVCLKEKFM

PRAMEF18

146

Q5VWM3
LEMKLTKVAMLICAG

OPN5

246

Q6U736
KVQGLEGIKMAMVAC

NEK8

606

Q86SG6
ETLKFEAIMMALKCG

KCTD4

221

Q8WVF5
FTGGMKEQDLMCIKL

KLHL9

81

Q9P2J3
CIMAEMLTGKTLFKG

MAPK13

211

O15264
AEKVFLAQKMMIGRC

PKLR

346

P30613
ALEGFKVMCKIIGIM

MSH6

861

P52701
CGMMEALLKVIKFLG

HUWE1

406

Q7Z6Z7
MKISCVLGKLLMLFE

OOSP4A

1

A0A2R8YFL7
FGCVIAQVGVMDMLK

PREP

571

P48147
KMMKVVQVACYEILG

EFCAB5

1286

A4FU69
LMIRGKLLKIFCAGM

ADAMTS9

1756

Q9P2N4
KFKEMVPIISQCGDM

CYP3A43

141

Q9HB55
FVATVGMKCMKCLED

CLDN1

96

O95832
MCLMKFVKGLGEVDC

ARFGEF3

1356

Q5TH69
MDMLFPGCISLKKVK

MAPRE2

91

Q15555
AVKMALATLCGGKIM

DTNA

131

Q9Y4J8
CFMGLCKVAKSVEML

SLC2A3

106

P11169
MVIKMVALGLFGQKC

CACNA1H

151

O95180
MSVKGMAIALAVILC

CXCL11

1

O14625
MFSMGCNVEIKKFLG

SLC10A2

46

Q12908
MGIIIVMSAKCKCKF

FXYD3

51

Q14802
AMIPCFGAKEEVSMK

GPRASP1

641

Q5JY77
VEGMVFCSVECKKRM

TES

406

Q9UGI8
FRQGFMKCLLEVEKM

SPATA21

81

Q7Z572
INKDLLMAAGCIKMT

RESF1

416

Q9HCM1
VAKILCMVGVFFFML

SLC39A3

6

Q9BRY0
FVLMGCSVFMTAILK

SLC4A8

886

Q2Y0W8
MKCLMEKLFDFLGSL

HERC2P3

806

Q9BVR0
NMMEIEKVKGFCQVV

SLC12A4

751

Q9UP95
MMVPADVFVGICAKF

B3GALT9

266

A8MXE2
MMTKHKKCFIIVGVL

CLEC2B

1

Q92478
AELVFKCVKGFMMEM

C12orf4

491

Q9NQ89
NCMMVRVFGKGFKEL

VWDE

941

Q8N2E2
KAIEVMYAQCMEVGK

TPST2

216

O60704
EAVGKMGFVVTMLKL

ZER1

516

Q7Z7L7
VGIMFLVGSKIVEMK

SLC1A4

271

P43007
VAVFTGECVMKMFAL

SCN10A

1516

Q9Y5Y9
CMFRTEKIRKLVAMG

TBC1D8

491

O95759
LLVEGFTIKKPMAMC

TTLL3

531

Q9Y4R7
AGTDEKMLMKVFRCL

TNPO3

191

Q9Y5L0
CLKGIMGVKDFEENM

VPS13B

456

Q7Z7G8
RFKKCIAVGMAMDLV

THRA

111

P10827
MVCKKIFMLAASVGI

ZBTB10

781

Q96DT7
DMAKVMIVMLAICFL

PTH

6

P01270
MDVACKVMLGGKNVE

ZFYVE26

2371

Q68DK2
AFMVKNIVPKLGMCL

TFIP11

606

Q9UBB9
IVDAFLIGCMFIKMS

KCNJ3

171

P48549
VKLNCMAMGIPKADI

MXRA5

2751

Q9NR99
DFIRMCTAMKKIGLD

MYO6

316

Q9UM54