Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentcell cortex

APC TBCB SPTBN5 RAI14 PLEKHH2 BSN FAM110C PDLIM2 EPB41L2 PHLDB2

4.23e-0537111610GO:0005938
GeneOntologyCellularComponentanchoring junction

CDHR2 PKP4 APC AMBRA1 SRCIN1 FAT1 NOX1 ABI2 PKP3 SCN5A RAI14 PDLIM2 CDH7 ARHGAP21 EPB41L2 PHLDB2

9.76e-0597611616GO:0070161
DomainPH

DOCK11 SPTBN5 SBF1 ARHGAP25 PLEKHH2 PREX1 ARHGAP21 PHLDB2

8.67e-052291158PF00169
DomainMultidrug-R_assoc

ABCC1 ABCC6

2.24e-0441152IPR005292
DomainARM-type_fold

DOCK11 PKP4 UBR4 USP24 APC HUWE1 WDFY4 MTOR PKP3

2.50e-043391159IPR016024
DomainPH_dom-like

DOCK11 WDFY4 SPTBN5 SBF1 ARHGAP25 PLEKHH2 PREX1 ARHGAP21 EPB41L2 PHLDB2

3.03e-0442611510IPR011993
DomainPH

DOCK11 SPTBN5 SBF1 ARHGAP25 PLEKHH2 PREX1 ARHGAP21 PHLDB2

3.26e-042781158SM00233
DomainPH_DOMAIN

DOCK11 SPTBN5 SBF1 ARHGAP25 PLEKHH2 PREX1 ARHGAP21 PHLDB2

3.34e-042791158PS50003
DomainPH_domain

DOCK11 SPTBN5 SBF1 ARHGAP25 PLEKHH2 PREX1 ARHGAP21 PHLDB2

3.42e-042801158IPR001849
DomainUIM

HUWE1 USP37 ANKIB1

4.19e-04241153PS50330
DomainUIM_dom

HUWE1 USP37 ANKIB1

4.74e-04251153IPR003903
DomainNa_trans_cytopl

SCN5A SCN9A

5.55e-0461152PF11933
DomainNa_trans_cytopl

SCN5A SCN9A

5.55e-0461152IPR024583
DomainCadherin_CS

PCDHGC4 PCDHGB7 CDHR2 FAT1 CDH7

5.69e-041091155IPR020894
DomainCADHERIN_1

PCDHGC4 PCDHGB7 CDHR2 FAT1 CDH7

6.71e-041131155PS00232
DomainCadherin

PCDHGC4 PCDHGB7 CDHR2 FAT1 CDH7

6.71e-041131155PF00028
DomainCADHERIN_2

PCDHGC4 PCDHGB7 CDHR2 FAT1 CDH7

6.98e-041141155PS50268
Domain-

PCDHGC4 PCDHGB7 CDHR2 FAT1 CDH7

6.98e-0411411552.60.40.60
Domain-

DOCK11 SPTBN5 SBF1 ARHGAP25 PLEKHH2 PREX1 ARHGAP21 EPB41L2 PHLDB2

7.03e-0439111592.30.29.30
DomainCA

PCDHGC4 PCDHGB7 CDHR2 FAT1 CDH7

7.26e-041151155SM00112
DomainCadherin-like

PCDHGC4 PCDHGB7 CDHR2 FAT1 CDH7

7.55e-041161155IPR015919
DomainPlakophilin/d_Catenin

PKP4 PKP3

7.74e-0471152IPR028435
DomainCadherin

PCDHGC4 PCDHGB7 CDHR2 FAT1 CDH7

8.16e-041181155IPR002126
DomainArm

PKP4 APC PKP3

9.01e-04311153PF00514
DomainPH_dom-spectrin-type

SPTBN5 ARHGAP25

1.32e-0391152IPR001605
DomainNa_channel_asu

SCN5A SCN9A

1.64e-03101152IPR001696
DomainNa_trans_assoc

SCN5A SCN9A

1.64e-03101152IPR010526
DomainNa_trans_assoc

SCN5A SCN9A

1.64e-03101152PF06512
DomainARM_REPEAT

PKP4 APC PKP3

1.90e-03401153PS50176
DomainARM

PKP4 APC PKP3

1.90e-03401153SM00185
DomainWWE

HUWE1 PARP12

2.38e-03121152PF02825
DomainWWE-dom

HUWE1 PARP12

2.38e-03121152IPR004170
DomainWWE

HUWE1 PARP12

2.38e-03121152PS50918
DomainUBA

MARK3 USP24 HUWE1

2.51e-03441153IPR015940
DomainArmadillo

PKP4 APC PKP3

3.03e-03471153IPR000225
DomainUBA

MARK3 USP24 HUWE1

3.03e-03471153PS50030
Domain-

STXBP5L DYNC2I1 AMBRA1 WDFY4 NUP133 SEMA6A WDR86

4.56e-0333311572.130.10.10
DomainWD40/YVTN_repeat-like_dom

STXBP5L DYNC2I1 AMBRA1 WDFY4 NUP133 SEMA6A WDR86

4.71e-033351157IPR015943
DomainTF_T-box

TBX18 MGA

4.81e-03171152IPR001699
DomainTBOX

TBX18 MGA

4.81e-03171152SM00425
DomainTF_T-box_CS

TBX18 MGA

4.81e-03171152IPR018186
Domain-

TBX18 MGA

4.81e-031711522.60.40.820
DomainTBOX_3

TBX18 MGA

4.81e-03171152PS50252
DomainT-box

TBX18 MGA

4.81e-03171152PF00907
DomainTBOX_1

TBX18 MGA

4.81e-03171152PS01283
DomainTBOX_2

TBX18 MGA

4.81e-03171152PS01264
DomainUIM

USP37 ANKIB1

5.39e-03181152PF02809
DomainLig_chan-Glu_bd

GRID1 GRIN2A

5.39e-03181152PF10613
DomainGlu/Gly-bd

GRID1 GRIN2A

5.39e-03181152IPR019594
DomainLig_chan-Glu_bd

GRID1 GRIN2A

5.39e-03181152SM00918
DomainIontro_rcpt

GRID1 GRIN2A

5.39e-03181152IPR001320
DomainIono_rcpt_met

GRID1 GRIN2A

5.39e-03181152IPR001508
DomainLig_chan

GRID1 GRIN2A

5.39e-03181152PF00060
DomainPBPe

GRID1 GRIN2A

5.39e-03181152SM00079
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NOP56 DOCK11 PKP4 UBR4 APC GRIN2A HUWE1 LUZP1 SBF1 ABI2 MTOR TMED10 BSN MGA ARHGAP21 CEP170B NUP153 EPB41L2 PHLDB2 SMG6

7.78e-119631172028671696
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DOCK11 MARK3 KIAA0232 APC GLCCI1 LUZP1 FAM83H LIMK2 IGF1R ALMS1 SBF1 MTOR RAI14 ARHGAP21 ABTB2 CEP170B EPB41L2 PHLDB2

6.85e-108611171836931259
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TSHZ2 STXBP5L MARK3 KIAA0232 PPFIA2 DYNC2I1 SRCIN1 HUWE1 ADCY1 ATF6 PPP2R3A IGF1R BRI3BP GLI2 PKP3 ANKIB1 RAI14 SEMA6A SERINC5 SCARA3 CEP170B SMG6

4.66e-0914891172228611215
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

REPS1 UBR4 AMBRA1 GRID1 HUWE1 MLLT10 POM121C FAM83H FAT1 IGF1R SBF1 MTOR SCN5A SCARA3 PREX1 ARHGAP21 ABTB2 CEP170B SMG6

5.42e-0911051171935748872
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

NOP56 PPFIA2 PKP4 PODXL2 SRCIN1 GRIN2A LUZP1 BSN CEP170B EPB41L2

6.59e-092311171016452087
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NOP56 RB1 PKP4 UBR4 SMC4 AMBRA1 HUWE1 LUZP1 FAM83H TBCB SBF1 NUP133 ANKIB1 RAI14 MGA RIOK2 EPB41L2 PHLDB2 PARP12

1.32e-0713531171929467282
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ABCC1 MARK3 PKP4 IGF1R SBF1 ABI2 RAI14 SEMA6A ARHGAP21 EPB41L2 PHLDB2

1.97e-074211171136976175
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

REPS1 MARK3 APC DYNC2I1 GRIN2A LUZP1 SBF1 TRAPPC10 RAI14 ARHGAP21 CEP170B

2.44e-074301171132581705
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

NOP56 PPFIA2 PKP4 SRCIN1 LUZP1 BSN CEP170B SMG6

7.95e-07218117833378226
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

UBR4 ANKIB1 RAI14 SEMA6A KIF17 PREX1 ARHGAP21

9.19e-07153117710718198
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

REPS1 MARK3 PKP4 SMC4 APC HUWE1 LUZP1 FAM83H TBCB IGF1R PKP3 TRAPPC10 RAI14 MED26 MGA PHLDB2 PARP12

9.77e-0712471171727684187
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

APC DYNC2I1 AMBRA1 HUWE1 USP37 FAM83H SBF1 NUP153

1.27e-06232117825515538
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

UBR4 USP24 APC RUSC1 HUWE1 LUZP1 ALMS1 RAI14 MGA ARHGAP21

1.61e-064181171034709266
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

NOP56 UBR4 USP24 SMC4 APC LUZP1 ATF6 FAT1 BRI3BP PKP3 RAI14 ECEL1 EEA1 TMED10 RIOK2 SCARA3 EPB41L2

1.67e-0612971171733545068
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

REPS1 MARK3 RBM4B PKP4 SMC4 APC MRPS35 LUZP1 SBF1 ABI2 RBM15B RAI14 TMED10 PREX1 PDLIM2 CEP170B EPB41L2 SMG6

2.69e-0614971171831527615
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

STXBP5L PPFIA2 PKP4 APC SRCIN1 GRIN2A GLCCI1 BSN CEP170B

2.83e-06347117917114649
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

MAP9 PKP4 SRCIN1 RAI14 ARHGAP21

3.23e-0667117529254152
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

NOP56 MARK3 PKP4 SRCIN1 LUZP1 FAM83H PKP3 RAI14 FAM110C ARHGAP21 PHLDB2

3.47e-065651171125468996
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ABCC1 MARK3 PKP4 FAT1 NOX1 MTOR SEMA6A FAM110C ARHGAP21 EPB41L2 PHLDB2

3.71e-065691171130639242
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

PPFIA2 PKP4 SRCIN1 GRIN2A LUZP1 MTOR CEP170B EPB41L2

5.24e-06281117828706196
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

KRT1 ABCC1 STBD1 NOP56 ATF6 NUP133 SEMA6A NUP153 EPB41L2

5.31e-06375117932788342
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

KRT1 MAP9 MARK3 PPFIA2 PKP4 APC SRCIN1 GRIN2A LUZP1 SBF1 LRIG1 TRAPPC10 RAI14 BSN ARHGAP21 CEP170B EPB41L2

6.17e-0614311171737142655
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

KIAA0232 PKP4 APC DYNC2I1 LUZP1 FAM83H TBCB PPP2R3A ALMS1 ABI2 MGA ARHGAP21 CEP170B

6.29e-068531171328718761
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KRT1 MAP9 NOP56 PCDHGC4 PCDHGB7 PPFIA2 UBR4 SMC4 MRPS35 LUZP1 TBCB CFAP45 SCN9A EEA1 BSN PREX1 ARHGAP21

6.82e-0614421171735575683
Pubmed

Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.

APC LRIG1

1.12e-052117224833705
Pubmed

Hepatic conditional knockout of ATF6 exacerbates liver metabolic damage by repressing autophage through MTOR pathway.

ATF6 MTOR

1.12e-052117230236984
Pubmed

Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice.

GRIN2A KIF17

1.12e-052117212391294
Pubmed

Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum.

ABCC1 ABCC6

1.12e-052117210835642
Pubmed

Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract.

RB1 APC

1.12e-052117216585182
Pubmed

p600, a unique protein required for membrane morphogenesis and cell survival.

RB1 UBR4

1.12e-052117216214886
Pubmed

Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter.

ABCC1 ABCC6

1.12e-052117210811882
Pubmed

TMP21 modulates cell growth in papillary thyroid cancer cells by inducing autophagy through activation of the AMPK/mTOR pathway.

MTOR TMED10

1.12e-052117226617795
Pubmed

Decreased LRIG1 in Human Ovarian Cancer Cell SKOV3 Upregulates MRP-1 and Contributes to the Chemoresistance of VP16.

ABCC1 LRIG1

1.12e-052117227183435
Pubmed

Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish.

APC MTOR

1.12e-052117224092877
Pubmed

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

SCN5A SCN9A

1.12e-052117226861708
Pubmed

Roles of Nup133, Nup153 and membrane fenestrations in assembly of the nuclear pore complex at the end of mitosis.

NUP133 NUP153

1.12e-052117230821042
Pubmed

GSK1904529A, a Potent IGF-IR Inhibitor, Reverses MRP1-Mediated Multidrug Resistance.

ABCC1 IGF1R

1.12e-052117228266043
Pubmed

TMP21 regulates autophagy by modulating ROS production and mTOR activation.

MTOR TMED10

1.12e-052117231472964
Pubmed

Retinoic Acid-Induced Protein 14 (RAI14) Promotes mTOR-Mediated Inflammation Under Inflammatory Stress and Chemical Hypoxia in a U87 Glioblastoma Cell Line.

MTOR RAI14

1.12e-052117230554401
Pubmed

Phosphorylation of P-Rex1 at serine 1169 participates in IGF-1R signaling in breast cancer cells.

IGF1R PREX1

1.12e-052117223899556
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

REPS1 NOP56 DOCK11 PKP4 SMC4 MRPS35 HUWE1 ARHGAP25 MGA PREX1 ARHGAP21 NUP153 EPB41L2

1.34e-059161171332203420
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

ABCC1 UBR4 USP24 SMC4 HUWE1 POM121C ATF6 BRI3BP LRIG1 MTOR NUP133 TMED10 NUP153

1.80e-059421171331073040
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

DOCK11 MARK3 PKP4 APC LUZP1 ALMS1 TRAPPC10 CEP170B PHLDB2

2.11e-05446117924255178
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

KRT1 NOP56 MARK3 PKP4 SMC4 MRPS35 LUZP1 FAM83H PKP3 NUP133 RBM15B RAI14 NUP153 EPB41L2 PHLDB2

2.16e-0512571171536526897
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

RB1 PKP4 AMBRA1 POM121C LUZP1 FAM83H LIMK2 FAT1 ALMS1 SCN5A MGA PDLIM2 CEP170B PHLDB2

2.41e-0511161171431753913
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

UBR4 SMC4 MRPS35 AMBRA1 HUWE1 LUZP1 SBF1 MTOR PKP3 NUP133 TMED10 ABTB2 NUP153

2.54e-059741171328675297
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

STBD1 REPS1 NOP56 MARK3 USP24 SMC4 APC RAI14 ARHGAP21 NUP153 EPB41L2

2.83e-057081171139231216
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

STXBP5L PPFIA2 UBR4 USP24 APC MRPS35 SRCIN1 GRIN2A HUWE1 TBCB ABI2 BSN CEP170B EPB41L2

3.01e-0511391171436417873
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

STBD1 APC POM121C ALMS1 NUP133 ARHGAP21 NUP153

3.19e-05263117734702444
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

DOCK11 TSHZ2 CEACAM4 SMC4 GLCCI1 LRIG1 RBAK MGA

3.31e-05363117814691545
Pubmed

STC1 interference on calcitonin family of receptors signaling during osteoblastogenesis via adenylate cyclase inhibition.

ADCY1 CALCRL

3.36e-053117225591908
Pubmed

USP22 exerts tumor-suppressive functions in colorectal cancer by decreasing mTOR activity.

APC MTOR

3.36e-053117231527800
Pubmed

KIF17 stabilizes microtubules and contributes to epithelial morphogenesis by acting at MT plus ends with EB1 and APC.

APC KIF17

3.36e-053117220696710
Pubmed

Plakophilin3 loss leads to increased adenoma formation and rectal prolapse in APCmin mice.

APC PKP3

3.36e-053117234823217
Pubmed

Expression and localization of ATP binding cassette (ABC) family of drug transporters in gastric hepatoid adenocarcinomas.

ABCC1 ABCC6

3.36e-053117218439156
Pubmed

Cloning and characterization of a novel Kruppel-associated box family transcriptional repressor that interacts with the retinoblastoma gene product, RB.

RB1 RBAK

3.36e-053117210702291
Pubmed

E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling.

APC HUWE1

3.36e-053117228137882
Pubmed

MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin.

IGF1R MTOR

3.36e-053117228315335
Pubmed

Synaptic Interactome Mining Reveals p140Cap as a New Hub for PSD Proteins Involved in Psychiatric and Neurological Disorders.

SRCIN1 GRIN2A

3.36e-053117228713243
Pubmed

Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier.

APC LRIG1

3.36e-053117231813825
Pubmed

p53 suppresses carcinoma progression by inhibiting mTOR pathway activation.

RB1 MTOR

3.36e-053117224469052
Pubmed

Epithelial IGF1R is dispensable for IGF2 mediated enhanced intestinal adaptation in retinoblastoma-deficient mice.

RB1 IGF1R

3.36e-053117228343662
Pubmed

Stress and IGF-I differentially control cell fate through mammalian target of rapamycin (mTOR) and retinoblastoma protein (pRB).

RB1 MTOR

3.36e-053117218697743
Pubmed

Pseudoxanthoma elasticum: Point mutations in the ABCC6 gene and a large deletion including also ABCC1 and MYH11.

ABCC1 ABCC6

3.36e-053117211439001
Pubmed

Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.

APC IGF1R

3.36e-053117226364612
Pubmed

Expression of the proliferating cell nuclear antigen and protein products of tumour suppressor genes in the human foetal testis.

RB1 APC

3.36e-053117214871261
Pubmed

IGF-2 mediates intestinal mucosal hyperplasia in retinoblastoma protein (Rb)-deficient mice.

RB1 IGF1R

3.36e-053117223845628
Pubmed

ARHGAP25 Inhibits Pancreatic Adenocarcinoma Growth by Suppressing Glycolysis via AKT/mTOR Pathway.

MTOR ARHGAP25

3.36e-053117233994864
Pubmed

PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway.

NOX1 MTOR

3.36e-053117237224811
Pubmed

SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions.

APC LRIG1

3.36e-053117237166989
Pubmed

ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo.

ATF6 MTOR

3.36e-053117218650380
Pubmed

mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR.

IGF1R MTOR

3.36e-053117226584640
Pubmed

NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression.

APC NOX1

3.36e-053117231365870
Pubmed

Targeted ablation of Abcc1 or Abcc3 in Abcc6(-/-) mice does not modify the ectopic mineralization process.

ABCC1 ABCC6

3.36e-053117217845218
Pubmed

Adipose-Derived VEGF-mTOR Signaling Promotes Endometrial Hyperplasia and Cancer: Implications for Obese Women.

ALMS1 MTOR

3.36e-053117229133593
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN5A SCN9A

3.36e-053117220038812
Pubmed

Transfer of Functional Cargo in Exomeres.

APC LRIG1

3.36e-053117230956133
Pubmed

Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation.

RB1 MTOR

3.36e-053117220628002
Pubmed

Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.

RB1 APC

3.36e-053117218832169
Pubmed

Blood vessel epicardial substance reduces LRP6 receptor and cytoplasmic β-catenin levels to modulate Wnt signaling and intestinal homeostasis.

APC LRIG1

3.36e-053117230689807
Pubmed

Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells.

IGF1R MTOR

3.36e-053117222729283
Pubmed

TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells.

IGF1R MTOR

3.36e-053117219020730
Pubmed

HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.

AMBRA1 HUWE1

3.36e-053117231434979
Pubmed

BYSL contributes to tumor growth by cooperating with the mTORC2 complex in gliomas.

MTOR RIOK2

3.36e-053117233628587
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

NOP56 APC MRPS35 DYNC2I1 AMBRA1 GLCCI1 FAM83H RBAK NUP133 RAI14 EEA1 CEP170B NUP153 MYBL1

3.51e-0511551171420360068
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

KRT1 REPS1 PPFIA2 RAI14 PREX1

3.81e-05111117522558309
Pubmed

A human MAP kinase interactome.

RBM4B KIAA0232 APC POM121C ATF6 MGA ZBTB18 NUP153 EPB41L2

4.11e-05486117920936779
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEC16B USP37 POM121C WDFY4 ALMS1 ARHGAP25 PLEKHH2 MGA PREX1

4.59e-05493117915368895
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

MARK3 APC MTOR RAI14 ARHGAP21 PHLDB2

4.65e-05190117615161933
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

STBD1 POM121C BRI3BP RAI14 NUP153 EPB41L2

4.78e-05191117631177093
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

NOP56 RBM4B MRPS35 HUWE1 LUZP1 SPTBN5 CFAP45 RBM15B PHLDB2

4.81e-05496117931343991
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

NOP56 DOCK11 SMC4 SRCIN1 IGF1R SCN9A RAI14 CDH7 ARHGAP21

4.88e-05497117936774506
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

USP24 APC HUWE1 GLCCI1 PKP3 NUP133 NUP153 EPB41L2 PHLDB2

5.35e-05503117916964243
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

NOP56 UBR4 USP24 SMC4 HUWE1 FAM83H MTOR NUP133 NUP153 EPB41L2

6.18e-056381171033239621
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

MAP9 UBR4 APC MRPS35 HUWE1 MMRN1 FAT1 SBF1 ANKIB1 PHLDB2

6.26e-056391171023443559
Pubmed

[Role of PTEN protein in multidrug resistance of prostate cancer cells].

ABCC1 MTOR

6.70e-054117218702307
Pubmed

Pathogenicity of lupus anti-ribosomal P antibodies: role of cross-reacting neuronal surface P antigen in glutamatergic transmission and plasticity in a mouse model.

GRIN2A BSN

6.70e-054117225709106
Pubmed

Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles.

APC IGF1R

6.70e-054117212595570
Pubmed

A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma.

MTOR RIOK2

6.70e-054117223459592
Pubmed

TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation.

UBR4 HUWE1

6.70e-054117237324936
InteractionSFN interactions

CCDC125 KRT1 DOCK11 MARK3 KIAA0232 APC LUZP1 FAM83H IGF1R ALMS1 MTOR PKP3 EEA1 ARHGAP21 CEP170B EPB41L2 PHLDB2

3.99e-0769211517int:SFN
InteractionYWHAE interactions

CCDC125 STBD1 DOCK11 MARK3 KIAA0232 APC SRCIN1 HUWE1 GLCCI1 LUZP1 FAM83H TBCB IGF1R SBF1 ABI2 MTOR RAI14 MGA FAM110C ARHGAP21 CEP170B EPB41L2 PHLDB2

5.56e-07125611523int:YWHAE
InteractionYWHAH interactions

CCDC125 DOCK11 MARK3 KIAA0232 APC HUWE1 GLCCI1 LUZP1 FAM83H TBCB ALMS1 SBF1 ABI2 MTOR RBM15B TRAPPC10 RAI14 ARHGAP21 CEP170B EPB41L2 PHLDB2

9.95e-07110211521int:YWHAH
InteractionMKRN2 interactions

RB1 RBM4B APC ADCY1 TBCB ALMS1 MTOR GLI2 SEMA6A PLEKHH2 PDLIM2 PARP12

2.09e-0638511512int:MKRN2
InteractionYWHAG interactions

DOCK11 MARK3 KIAA0232 USP24 APC HUWE1 USP37 GLCCI1 LUZP1 FAM83H IGF1R ALMS1 SBF1 MTOR RBM15B TRAPPC10 RAI14 ARHGAP21 CEP170B EPB41L2 PHLDB2

7.03e-06124811521int:YWHAG
InteractionMAPRE1 interactions

MAP9 REPS1 APC LUZP1 FAM83H TBCB ALMS1 PKP3 NUP133 MED26 ARHGAP21 CEP170B NUP153

7.58e-0651411513int:MAPRE1
InteractionC11orf52 interactions

ABCC1 MARK3 PKP4 IGF1R SBF1 RAI14 SEMA6A ARHGAP21 EPB41L2 PHLDB2

1.18e-0531111510int:C11orf52
InteractionARHGEF7 interactions

REPS1 HUWE1 NOX1 MTOR GLI2 PREX1 ARHGAP21

2.80e-051531157int:ARHGEF7
InteractionSLC6A4 interactions

REPS1 MARK3 APC DYNC2I1 GRIN2A LUZP1 SBF1 TRAPPC10 RAI14 ARHGAP21 CEP170B

4.14e-0543711511int:SLC6A4
InteractionRHOQ interactions

ABCC1 DOCK11 MARK3 PKP4 MUC13 FAT1 SBF1 MTOR RAI14 SEMA6A ARHGAP21

4.58e-0544211511int:RHOQ
InteractionTFDP3 interactions

RB1 UBR4 FAM83H ALMS1

5.15e-05361154int:TFDP3
InteractionRAC3 interactions

ABCC1 STBD1 DOCK11 MARK3 PKP4 PODXL2 MUC13 FAT1 SBF1 ABI2 RAI14 ARHGAP21 PHLDB2

5.29e-0561911513int:RAC3
InteractionLAMP1 interactions

ABCC1 STBD1 MARK3 PKP4 UBR4 HUWE1 IGF1R SBF1 ABI2 MTOR RAI14 ARHGAP21 EPB41L2

7.90e-0564411513int:LAMP1
InteractionC2CD4B interactions

RB1 KIAA0232 APC FAT1

1.15e-04441154int:C2CD4B
InteractionRHOF interactions

ABCC1 DOCK11 MARK3 PKP4 PODXL2 MUC13 POM121C FAT1 SBF1 ABI2 MTOR RAI14 ARHGAP21

1.23e-0467311513int:RHOF
InteractionRAC2 interactions

ABCC1 STBD1 DOCK11 MARK3 PKP4 MUC13 FAT1 SBF1 ABI2 MTOR PKP3 ARHGAP21 PHLDB2

1.24e-0467411513int:RAC2
Cytoband16p13.1

ABCC1 ABCC6

3.85e-054117216p13.1
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK11 SBF1 ARHGAP25 PLEKHH2 PREX1 ARHGAP21 PHLDB2

4.85e-05206847682
GeneFamilySodium voltage-gated channel alpha subunits

SCN5A SCN9A

7.52e-0498421203
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PKP4 APC PKP3

1.04e-0343843409
GeneFamilyATP binding cassette subfamily C

ABCC1 ABCC6

1.61e-0313842807
GeneFamilyCadherin related

CDHR2 FAT1

2.77e-031784224
GeneFamilyT-boxes

TBX18 MGA

3.11e-0318842766
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

RB1 APC IGF1R GLI2

6.11e-06271174M1391
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

RB1 APC IGF1R GLI2

6.11e-06271174MM1135
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ABCC1 RB1 MARK3 PKP4 USP24 APC FAT1 PPP2R3A IGF1R LRIG1 NUP133 ZBTB18 NUP153 MYBL1

2.88e-0585611714M4500
CoexpressionGSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_DN

SEMG2 STXBP5L SPTBN5 LIMK2 PPP2R3A PDLIM2 MYBL1

3.10e-051981177M7261
CoexpressionGSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP

RB1 SPNS2 IGF1R ALMS1 ECEL1 FAM110C PHLDB2

3.21e-051991177M5692
CoexpressionGSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_UP

CCDC125 MAP9 B4GALNT1 TSHZ2 PKP4 IGF1R BRI3BP

3.31e-052001177M6352
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TSHZ2 SPNS2 MMRN1 LIMK2 RAI14 SEMA6A CALCRL

5.58e-071831177bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPNS2 PKP4 MMRN1 RAI14 SEMA6A CALCRL CDH7

7.71e-07192117781baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCellTCGA-Skin-Metastatic-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

DOCK11 SMC4 USP37 ALMS1 ARHGAP25 CALCRL EPB41L2

9.47e-071981177af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCellTCGA-Skin-Metastatic|TCGA-Skin / Sample_Type by Project: Shred V9

DOCK11 SMC4 USP37 ALMS1 ARHGAP25 CALCRL EPB41L2

9.47e-071981177ad39cce004867f083f8da1954e0cf5a263815184
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

DOCK11 SMC4 USP37 ALMS1 ARHGAP25 CALCRL EPB41L2

9.47e-07198117762cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4C GRIN2A ADCY1 SCN9A SEMA6A PLEKHH2

3.87e-061581176f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4C GRIN2A ADCY1 SCN9A SEMA6A PLEKHH2

3.87e-0615811768c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 TMEM198 GRID1 GRIN2A GLI2 EPB41L2

5.50e-061681176d19a115365c5415e51c039718d7669de788fcf33
ToppCellEndothelial-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PTCHD3 TSHZ2 MMRN1 SEMA6A CALCRL SCARA3

5.69e-06169117695c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCellClub_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

TSHZ2 SPNS2 MUC13 NOX1 GLI2 ADGRF1

5.69e-06169117603b303af8a26c6ff196507fe24f5bd3d75d7b1af
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMRN1 SCN9A SEMA6A CALCRL EPB41L2 PHLDB2

7.66e-061781176ad3de3e03a401dac64431a541899445262246347
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

SPNS2 MMRN1 ARHGAP25 SEMA6A CALCRL MYBL1

7.91e-061791176d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

TSHZ2 MMRN1 SCN9A RAI14 SEMA6A CALCRL

7.91e-061791176411620201a860716a8773b92f50f7b94ef34a586
ToppCellILEUM-non-inflamed-(7)_Lymphatics|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TSHZ2 MMRN1 RAI14 SEMA6A CALCRL EPB41L2

7.91e-06179117699777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMRN1 SCN9A SEMA6A CALCRL EPB41L2 PHLDB2

8.43e-061811176e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMRN1 SCN9A SEMA6A CALCRL EPB41L2 PHLDB2

8.97e-0618311764d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

TSHZ2 CDHR2 SPNS2 MUC13 NOX1 ADGRF1

9.26e-061841176d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

TSHZ2 MMRN1 SCN9A RAI14 SEMA6A CALCRL

9.55e-0618511764a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SPNS2 PKP4 MMRN1 RAI14 SEMA6A CALCRL

9.55e-061851176f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

TSHZ2 MMRN1 SCN9A RAI14 SEMA6A CALCRL

9.55e-06185117636ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMRN1 SCN9A SEMA6A CALCRL EPB41L2 PHLDB2

9.84e-06186117640070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMRN1 SCN9A SEMA6A CALCRL EPB41L2 PHLDB2

9.84e-06186117620340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

PDE4C TSHZ2 TBX18 FAT1 SEMA6A PHLDB2

1.08e-05189117646e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

PPFIA2 PODXL2 FAT1 LOXL1 RAI14 PDLIM2

1.08e-05189117646c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SPNS2 PKP4 MMRN1 RAI14 SEMA6A CALCRL

1.11e-0519011761caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCellCOVID-19-Heart-EC_3|Heart / Disease (COVID-19 only), tissue and cell type

TSHZ2 SPNS2 PKP4 RAI14 SEMA6A CALCRL

1.11e-05190117678e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GRID1 GRIN2A LUZP1 SEMA6A CALCRL PREX1

1.14e-0519111761de0bdfd13bd930691564c2673f2e66393bc0255
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSHZ2 MMRN1 RAI14 SEMA6A CALCRL EPB41L2

1.21e-051931176bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCellLV-14._Fibroblast_III|LV / Chamber and Cluster_Paper

TSHZ2 TBX18 FAT1 SEMA6A ABTB2 PHLDB2

1.25e-051941176927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCellASK440-Endothelial-Lymphatic|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

TSHZ2 MMRN1 SEMA6A CALCRL EPB41L2 PHLDB2

1.25e-0519411764aa68e39e36094359dfbedf1e9bdf3ea5c32ed1a
ToppCellASK440-Endothelial|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

TSHZ2 MMRN1 SEMA6A CALCRL EPB41L2 PHLDB2

1.29e-0519511761cdaab17866a1e5170e0f6bfcc69134425fdd8df
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPNS2 PKP4 FAT1 PPP2R3A ADGRF1 ABTB2

1.33e-051961176c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCelldistal-Endothelial-Lymphatic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTCHD3 TSHZ2 MMRN1 SCN9A SCARA3 PHLDB2

1.33e-0519611763e8a20e1d163dcbd3bbd99fe179d54af02298af0
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DYNC2I1 WDR86 PLEKHH2 BSN SCARA3 EPB41L2

1.36e-051971176fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellILEUM-non-inflamed-(7)_ACKR1+_endothelial_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SPNS2 PKP4 MMRN1 RAI14 SEMA6A CALCRL

1.40e-051981176f8a6a75c9f2fbe32a22b14b6a029411c73c09f68
ToppCellILEUM-inflamed-(7)_Endothelial_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SPNS2 PKP4 MMRN1 RAI14 SEMA6A CALCRL

1.44e-05199117697052c28e354833901f28d339b09f97f50a5b752
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PPFIA2 TBX18 PLEKHH2 SCARA3 ABTB2 EPB41L2

1.44e-051991176abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPNS2 PKP4 MMRN1 RAI14 SEMA6A CALCRL

1.49e-052001176cb00760ae75c30b1cb8526534aabd4ffc7c21000
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

USP24 HUWE1 ARHGAP25 PHLDB2 CXCR1 MYBL1

1.49e-0520011762281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellNeuronal-Excitatory-eC(RORB)-eC_2-C1R-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SEC16B TSHZ2 ARHGAP25 PLEKHH2 SCARA3 PHLDB2

1.49e-052001176891a80cbde575f81f3466217175f41e1d4f66d5e
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Bronchial_vessel-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPNS2 PKP4 MMRN1 RAI14 SEMA6A CALCRL

1.49e-052001176c55efd997392e99068b673542f56f1a209c5a6c8
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

PDE4C DOCK11 PPFIA2 PODXL2 FAT1 WDR86

1.49e-05200117669edc375d85689300d1dbc1217fedc40063ecdcb
ToppCellNeuronal-Excitatory-eC(RORB)-eC_2-C1R|Neuronal / cells hierarchy compared to all cells using T-Statistic

SEC16B TSHZ2 ARHGAP25 PLEKHH2 SCARA3 PHLDB2

1.49e-052001176c761d1742653a83e69e4c03d6e10e5e53f28bebb
ToppCellParenchyma_COVID-19-Endothelial-TX-Bronchial_vessel|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

SPNS2 PKP4 MMRN1 RAI14 SEMA6A CALCRL

1.49e-052001176a18817d36b2b30a32e1513d36174bf98dfea2a92
ToppCellNeuronal-Excitatory-eC(RORB)-eC_2-C1R--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

SEC16B TSHZ2 ARHGAP25 PLEKHH2 SCARA3 PHLDB2

1.49e-052001176dcbc91ed3351bafd72cf71d7025cbbdc8361d9b9
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Bronchial_vessel|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPNS2 PKP4 MMRN1 RAI14 SEMA6A CALCRL

1.49e-05200117671979bbcc035d5b8882f1502b5a8ef248aaba45a
ToppCell(54)_pDC|World / shred on Cell_type and subtype

CLN8 SCN9A CALCRL MED26 ZBTB18 KIF17

1.62e-052031176b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

B4GALNT1 GRID1 TBX18 GLI2 PLEKHH2

2.00e-051251175b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCell21-Trachea-Immune-Immune|Trachea / Age, Tissue, Lineage and Cell class

KRT1 PCDHGB7 PELI3 AMBRA1 ADCY1

2.79e-0513411754f0465324cc5b443ebadb68aef63be79b74f6ff9
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP45 PLEKHH2 ADGRF1 FAM110C CXCR1

3.68e-051421175191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CDHR2 MANSC4 ADGRF1 FAM110C

3.69e-057111742220e1b02baa71961cfc85536bafeb313e588bf3
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CDHR2 MANSC4 ADGRF1 FAM110C

3.69e-05711174cc5de8bbcfefa2bf93cc137c74b49a745d5da229
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CFAP45 PLEKHH2 ADGRF1 FAM110C CXCR1

3.81e-051431175b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX18 GLI2 LOXL1 MANSC4 ECEL1

4.48e-051481175dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high|E18.5-samps / Age Group, Lineage, Cell class and subclass

STXBP5L HFM1 SEMA6A ZBTB18 SCARA3

5.42e-051541175212c340a096a3a9669d1aebd61c045cf1402a868
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd|lymph-node_spleen / Manually curated celltypes from each tissue

CDHR2 SRCIN1 LIMK2 WDR86 PLEKHH2

5.59e-051551175b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCellVE-CD8-naive_CD4|VE / Condition, Cell_class and T cell subcluster

PKP4 PELI3 SPTBN5 WDR86 PLEKHH2

6.49e-051601175255d2a150bfe19ee3d4d34533feb9c37ce73d225
ToppCellfacs-Lung-24m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MUC13 WDFY4 BRI3BP PKP3 IL5RA

6.89e-0516211754e418bea07e35038b32a78a1e6632b6ec1208cdc
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CDHR2 MANSC4 ADGRF1 FAM110C

7.47e-05851174159b3ac93490c3e4918ea61f8ede7add9e63ca40
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC1 GRID1 MANSC4 MED26 MYBL1

7.51e-0516511751703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPFIA2 PELI3 LOXL1 PKP3 RBAK

7.73e-0516611759fd9de82f98b9acdaa59ac98fb9664161514aec0
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SPNS2 PKP4 MMRN1 RAI14 CALCRL

7.73e-051661175f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PCDHGB7 TSHZ2 SEMA6A PLEKHH2 PHLDB2

7.95e-0516711755c82d801e3b7d7c6c967a73b94b2ee2a8da1fd6e
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 FAT1 CALCRL PHLDB2 PARP12

8.41e-051691175bddb28a8b9afbe4a68f082e82caf96a6666fc674
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSHZ2 FAT1 CALCRL PHLDB2 PARP12

8.41e-0516911755ce46bac8e767feec7ecdc61689de225c49bd3f7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

GLCCI1 FAT1 LRIG1 RAI14 WDR86

8.65e-051701175269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPNS2 PKP4 MMRN1 SEMA6A CALCRL

8.65e-0517011751a568efcff9c39b3f709b55a05d24710450a2657
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5_RORB_LINC01202|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC16B TSHZ2 ARHGAP25 SCARA3 PHLDB2

8.65e-05170117587cac555f16b6c2ef3d1b3a00f992d8bf2237b50
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPNS2 PKP4 MMRN1 SEMA6A CALCRL

8.65e-05170117566d41d794790e621d72ac37af995510537103c9c
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

CLN8 MMRN1 SCN9A KIF17 CEP170B

8.89e-05171117572c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCellEndothelial-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

TSHZ2 MMRN1 SEMA6A CALCRL KIF17

9.13e-0517211758a527dff06d841a86c7eb04a1dd9630787294da4
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel|Adult / Lineage, Cell type, age group and donor

TSHZ2 SPNS2 CFAP45 SEMA6A CALCRL

9.13e-051721175ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

KRT1 TSHZ2 PLEKHH2 SCARA3 CXCR1

9.39e-0517311751f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STXBP5L PELI3 SRCIN1 ADCY1 BSN

9.39e-05173117507798461d12d04f3dabff03481c999cb07c5af2f
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSHZ2 MMRN1 RAI14 CALCRL EPB41L2

9.39e-0517311757dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B4GALNT1 SPNS2 ZBTB18 FAM110C SCARA3

9.91e-0517511753f1b2e23fec953148fb0711e523c463adb07dca4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STXBP5L ADCY1 GLCCI1 ALMS1 FAM110C

9.91e-05175117565571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 PPFIA2 GLI2 LOXL1 EPB41L2

1.02e-0417611759bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

TSHZ2 MMRN1 SEMA6A CALCRL EPB41L2

1.02e-04176117598c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ2 PPFIA2 GLI2 LOXL1 EPB41L2

1.02e-0417611753f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

TSHZ2 MMRN1 SEMA6A CALCRL EPB41L2

1.02e-041761175c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellmetastatic_Lymph_Node-Endothelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

MMRN1 SEMA6A CALCRL KIF17 SCARA3

1.05e-04177117571bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEC16B USP24 USP37 SEMA6A MYBL1

1.05e-0417711759edfb50856f5e10672ab194ce0076d6a190e64de
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 TSHZ2 GLCCI1 SERINC5 SCARA3

1.05e-041771175da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Esophagus_Squamous_Cell_Carcinoma-7|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

ABCC1 STXBP5L GLI2 SCN9A

1.06e-049311744ab8c28f7c47129ac633bcfdc7ccc8f7793464d5
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPNS2 MMRN1 RAI14 CALCRL KIF17

1.07e-041781175aa44851653d276226b922ee14dd1fc8d1a844cdf
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ2 LRIG1 PKP3 ECEL1 EEA1

1.07e-041781175888add8935ef3aef9b6693c5698e9d1842e66337
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ2 LRIG1 PKP3 ECEL1 EEA1

1.07e-04178117543eda32af2e5e28a92421612d0a4c21e5427a772
ToppCell10x3'2.3-week_12-13-Myeloid_macrophage-stroma-erythroid_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ABCC1 TSHZ2 GRID1 TBX18 PLEKHH2

1.10e-041791175c17ae394b855f01f8ca1765c416fd8b34a96e60b
ToppCellfacs-Pancreas-Exocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B4GALNT1 SPNS2 ZBTB18 FAM110C SCARA3

1.10e-041791175bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Neuronal-Cortical_neuron|GW12 / Sample Type, Dataset, Time_group, and Cell type.

TBCB SERINC5 ZBTB18 CDH7

1.11e-04941174a752c80fb2e83cffa22a00d7e98c24406ee41908
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ2 LOXL1 SEMA6A CALCRL EPB41L2

1.13e-041801175dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ2 LOXL1 SEMA6A CALCRL EPB41L2

1.13e-041801175423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellSevere-Lymphoid-pDC|Severe / Condition, Lineage, Cell class and cell subclass

WDFY4 MMRN1 SCN9A ECEL1 CALCRL

1.16e-0418111752caecb7c5dcdad46fd02b4ffb73cb613ce835187
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ2 PPFIA2 SEMA6A CALCRL PHLDB2

1.16e-041811175fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellfacs-Heart-LV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC125 B4GALNT1 CDHR2 ARHGAP25 IL5RA

1.16e-04181117557f82f54e20e19aa17a2ea22af22e3bc8965d622
ToppCellfacs-Heart-LV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC125 B4GALNT1 CDHR2 ARHGAP25 IL5RA

1.16e-0418111758855812c85ef45c1be6bd511619b2dfe5e441264
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

PKP4 WDFY4 ADCY1 WDR86 CALCRL

1.16e-0418111755a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCellSevere-Lymphoid-pDC-|Severe / Condition, Lineage, Cell class and cell subclass

WDFY4 MMRN1 SCN9A ECEL1 CALCRL

1.16e-041811175277ce4c49121da0990a5933b19d2c6af9bbe253e
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSHZ2 MMRN1 RAI14 CALCRL PHLDB2

1.19e-041821175fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
DiseaseDysosteosclerosis

SLC29A3 SCN9A

1.51e-0521152C0432262
DiseaseCD166 antigen measurement

ABCC1 ABCC6

8.99e-0541152EFO_0020245
DiseaseColorectal Neoplasms

ABCC1 APC GRID1 GRIN2A ABCC6 FAT1 CDH7

1.10e-042771157C0009404
DiseaseParoxysmal atrial fibrillation

PPP2R3A IGF1R LRIG1 SCN5A PHLDB2

3.72e-041561155C0235480
Diseasefamilial atrial fibrillation

PPP2R3A IGF1R LRIG1 SCN5A PHLDB2

3.72e-041561155C3468561
DiseasePersistent atrial fibrillation

PPP2R3A IGF1R LRIG1 SCN5A PHLDB2

3.72e-041561155C2585653
DiseaseAtrial Fibrillation

PPP2R3A IGF1R LRIG1 SCN5A PHLDB2

4.18e-041601155C0004238
Diseaseepilepsy (implicated_via_orthology)

GRIN2A SBF1 SCN5A SCN9A BSN

4.55e-041631155DOID:1826 (implicated_via_orthology)
DiseaseCarcinoma, Small Cell

RB1 MTOR

5.32e-0491152C0262584
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN5A SCN9A

6.64e-04101152DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN5A SCN9A

6.64e-04101152DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN5A SCN9A

9.69e-04121152DOID:0060170 (implicated_via_orthology)
Diseaseventricular enlargement measurement

ABCC1 SRCIN1

1.14e-03131152EFO_0010570
Diseaseforehead morphology measurement

CDH7 SMG6

1.53e-03151152EFO_0007844
DiseaseNeoplasm of uncertain or unknown behavior of bladder

RB1 MTOR

1.53e-03151152C0496930
DiseaseBenign neoplasm of bladder

RB1 MTOR

1.53e-03151152C0154017
DiseaseCarcinoma in situ of bladder

RB1 MTOR

1.53e-03151152C0154091
DiseaseMalignant neoplasm of skin

KRT1 IGF1R GLI2

1.60e-03591153C0007114
DiseaseSkin Neoplasms

KRT1 IGF1R GLI2

1.60e-03591153C0037286
Diseaselymphocyte count

ABCC1 SLC29A3 PCDHGC4 PCDHGB7 RB1 MARK3 KIAA0232 ALMS1 PKP3 HFM1 CALCRL PREX1 PARP12 SMG6

1.69e-03146411514EFO_0004587
DiseaseAdrenocortical carcinoma

RB1 IGF1R

2.21e-03181152C0206686
DiseaseCarcinoma of bladder

RB1 MTOR

2.21e-03181152C0699885
Diseasecolorectal cancer, inflammatory bowel disease

PTCHD3 ALMS1

2.47e-03191152EFO_0003767, MONDO_0005575
Diseaseresting heart rate

PPFIA2 SCN5A CALCRL ARHGAP21

2.80e-031491154EFO_0004351
Diseasegestational age, birth measurement

SLC29A3 PPP2R3A

3.01e-03211152EFO_0005112, EFO_0006921
Diseaseaortic measurement

TBX18 LRIG1 LOXL1 PREX1 SMG6

3.07e-032511155EFO_0020865
Diseaseatrial fibrillation

PPP2R3A IGF1R LRIG1 SCN5A ARHGAP21 PHLDB2

3.39e-033711156EFO_0000275
DiseaseGlioblastoma

APC FAT1 MTOR

3.68e-03791153C0017636
Diseasebody surface area

SEC16B PDE4C GRID1 LUZP1 IGF1R MTOR GLI2 EPB41L2

3.75e-036431158EFO_0022196

Protein segments in the cluster

PeptideGeneStartEntry
GNLQRTSSQRSTLTY

PKP4

451

Q99569
RNRYRTRSTSSAGSN

SMG6

251

Q86US8
TLRTINASYDSDQAT

CEACAM4

121

O75871
YRRTVNTFSQSVSSL

BRI3BP

46

Q8WY22
SSRSYQTNTADTVRF

B4GALNT1

226

Q00973
RFTNDLLNSSSAIYS

ADGRF1

161

Q5T601
TGIQIASSSSYSNRE

ALMS1

1886

Q8TCU4
SSLRDYTPASRSENQ

ANKIB1

826

Q9P2G1
AHYRSSSTRSIDTQT

GLCCI1

336

Q86VQ1
TQTYASQTRSESSSQ

ADAM32

741

Q8TC27
TSSISRNSGSELQVY

ATF6

531

P18850
YTQSSRSGTVSQEAL

AMBRA1

661

Q9C0C7
SNTRRRQQGSDYTST

CEP170B

1246

Q9Y4F5
TASVNQRNRTYSSSG

ABI2

231

Q9NYB9
ATYSRSTSQNLDSGT

RB1

496

P06400
LSQLSYSTSSSKRQS

RAI14

901

Q9P0K7
SSDRRNSLEGYSRSV

RBM15B

556

Q8NDT2
LESRTLSSYVSVSAQ

PCDHGB7

496

Q9Y5F8
YSRSRQATDGSLASI

NOX1

126

Q9Y5S8
YSTTSSCQARASQVR

PODXL2

481

Q9NZ53
YSARESLSEVQSLSS

FAT1

4356

Q14517
RERSSFYSLTSSNIS

NUP133

281

Q8WUM0
SFSSRVVSLSEYRQS

NOP56

266

O00567
AITARSARQRSSEYS

MAP9

31

Q49MG5
SYLSSQGTLSDRQET

LRIG1

841

Q96JA1
ASTTNDSGYRARISQ

MGA

691

Q8IWI9
RSESLRCSSSYSQQI

LIMK2

311

P53671
RGDSSSSQRTDYQKS

MMRN1

186

Q13201
SSVSASAFASTYRQQ

LOXL1

156

Q08397
SLAQYSATTAREISR

BSN

2086

Q9UPA5
RALYFSDSSSQLNTS

DYNC2I1

621

Q8WVS4
SSSAASNRSRNKARY

CFAP45

11

Q9UL16
RYSGRTQAQTRQAST

EPB41L2

516

O43491
SSRSRNTTAADTYNI

IGF1R

751

P08069
SAGIINYQRRTTSSS

KRT1

21

P04264
ETTYRNRQDTSDLTS

KIAA0232

421

Q92628
TSRSGNQVSEYISRT

PDE4C

251

Q08493
EQSPTYLNTRSSSNR

MANSC4

131

A6NHS7
LVAYINNSRSSSAAS

GLI2

256

P10070
DVGSNSISSYRLSSN

PCDHGC4

161

Q9Y5F7
SELSQASAATRNSLY

RBM4B

326

Q9BQ04
YRSLTRQSSDFDTQS

HUWE1

1991

Q7Z6Z7
SRNEIIQSYLSRQSS

MED26

481

O95402
IQSYLSRQSSLLSSS

MED26

486

O95402
ADLSRYNDQASSSRI

PPP2R3A

921

Q06190
SLTVSLDDRNSSRYV

ECEL1

246

O95672
QSQRLDYSSSSSEAN

PLEKHH2

391

Q8IVE3
RQAARRSTSTLYSQF

SBF1

1741

O95248
RSTSTLYSQFQTAES

SBF1

1746

O95248
YGATQARRLSTASSV

PARP12

351

Q9H0J9
SRNAITSSYSSTRGI

POM121C

386

A8CG34
STISSYLSDLRNRNA

HFM1

1171

A2PYH4
QYASSEATISQLRSE

EEA1

261

Q15075
LRNRSSFSTNVVYTT

ADCY1

546

Q08828
TTLNLFTVDQSYRSR

CDHR2

1036

Q9BYE9
NLTCTTNTTEDNYSR

IL5RA

131

Q01344
RISNYRRQSSTVDSN

CCDC125

91

Q86Z20
QSSTRSSVSQYNRLD

DOCK11

1261

Q5JSL3
LARHRVTSYTSSSVN

CXCR1

331

P25024
STNSNAYTQRSSTDF

LUZP1

946

Q86V48
QRSVSSSQKQRRYSD

MARK3

406

P27448
SSYTANLAAFLTVSR

GRID1

646

Q9ULK0
SSNSPVRYSIDRNTD

CDH7

406

Q9ULB5
ARLSSATANALYSSN

FAM83H

1021

Q6ZRV2
GLQRSQSDLSSRYSA

FAM110C

196

Q1W6H9
QNYTRLFSGLRTTST

SCARA3

256

Q6AZY7
SNSEALRSASYTVST

CALCRL

411

Q16602
EQARRYLSTYTATSS

MYBL1

731

P10243
TNDSYRFSASRRSTE

PTCHD3

191

Q3KNS1
SSRLQRLDNSTVRTY

PPFIA2

1241

O75334
SRSNSENIASNYFRS

KIF17

941

Q9P2E2
RSRTRTDSYSAGQSV

MTOR

2441

P42345
QRQLSSSSSYSGDIS

ABCC1

911

P33527
SSTRSLGTLYSQVSR

RUSC1

571

Q9BVN2
ARTLRAFSTAVYSAT

MRPS35

16

P82673
TYRTTSSSLRADQEA

SLC29A3

16

Q9BZD2
YRRDVTSAINLSASS

SLFN14

131

P0C7P3
SATTAIEIRRQSSSY

REPS1

261

Q96D71
QLRRLESASYSSVCS

ABCC6

1111

O95255
SNRGQHSISYTLSRS

PELI3

121

Q8N2H9
NRDSVLSYTSVRSNS

PREX1

1176

Q8TCU6
SYDSVTRATSDNLQV

SCN5A

1976

Q14524
DSEYSKVRLNRSSSS

SCN9A

1111

Q15858
ISYQSSSTEERRLNS

SEMG2

406

Q02383
RNRSYVFSSLATSAV

SPNS2

311

Q8IVW8
SENINLRTRKYSSSS

PHLDB2

231

Q86SQ0
GSVRTYTESQSSLRS

PDLIM2

106

Q96JY6
TASYTNVNITDFSRS

SPTBN5

191

Q9NRC6
EENRENSYNRSRSSS

STXBP5L

806

Q9Y2K9
NSYNRSRSSSISSID

STXBP5L

811

Q9Y2K9
SLRTSFSQSRYSVVQ

ABTB2

751

Q8N961
RGSNRSYDQSLSDSS

MLLT10

206

P55197
YKRSSNDSLNSVSSS

APC

956

P25054
SSSLNATYRSLVARE

CLN8

46

Q9UBY8
RAFAYERQASSSSSR

PKP3

211

Q9Y446
RSSSSNFLNYDLTLR

MUC13

311

Q9H3R2
TSNSRSYSEVSRNES

STBD1

131

O95210
SVRSLSTYSAAALQS

SRCIN1

431

Q9C0H9
RDTNESTNTRVLYFS

TMED10

176

P49755
STSLAETYNRLTNQA

TBX18

431

O95935
SISQLISSDGSYART

RBAK

146

Q9NYW8
QLDRASSSLYVAFST

SEMA6A

491

Q9H2E6
RQLSDSQRTSTYDNV

ARHGAP25

491

P42331
SSYFSSQDVLRSNLV

ZBTB18

256

Q99592
TSTTRSSSDALQGRY

SERINC5

331

Q86VE9
SSSLNTFRSEKRYSR

TBCB

16

Q99426
SQRDTVLSTLYSSLN

WDFY4

2001

Q6ZS81
SNFYVSRTACRDNTS

SMC4

181

Q9NTJ3
LSAQSYGVTSSTARR

NUP153

296

P49790
STRSASVSRRYLFEN

TSHZ2

746

Q9NRE2
QYRTRTLSITSSGSA

RIOK2

476

Q9BVS4
QRESGLSSSSYELSQ

SEC16B

226

Q96JE7
SRTSQKETSRQLSYS

USP37

126

Q86T82
EKSSYRQLSVSDRSS

USP24

1291

Q9UPU5
ESRAVVYSNTREQSS

TRAPPC10

836

P48553
VYSNTREQSSEAALR

TRAPPC10

841

P48553
SSTSASVNRYILQLA

UBR4

3786

Q5T4S7
RLDSLRAASQSTTDY

ARHGAP21

411

Q5T5U3
ANNQLFSSSYDRTAR

WDR86

106

Q86TI4
SYIQSFRDRQTGSSL

TMEM198

316

Q66K66
VNDSYLRSSLRSTAS

GRIN2A

1396

Q12879