Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

SYNJ1 SYNJ2

3.11e-046922GO:0043813
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

SGMS1 PAPOLA HIPK1 BTK KSR2 MAP3K14 PAK1 DLG1 AK9 LTBP1 DCLK2 PIGO ITPKA

3.57e-049389213GO:0016772
GeneOntologyMolecularFunctioninositol-1,4,5-trisphosphate 5-phosphatase activity

SYNJ1 SYNJ2

5.77e-048922GO:0052658
GeneOntologyMolecularFunctionkinase activity

SGMS1 HIPK1 BTK KSR2 MAP3K14 PAK1 DLG1 AK9 LTBP1 DCLK2 ITPKA

7.66e-047649211GO:0016301
GeneOntologyMolecularFunctionphosphatidylinositol-4,5-bisphosphate 5-phosphatase activity

SYNJ1 SYNJ2

9.22e-0410922GO:0004439
GeneOntologyMolecularFunctionphosphatidylinositol phosphate 4-phosphatase activity

SYNJ1 SYNJ2

9.22e-0410922GO:0034596
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity

SYNJ1 SYNJ2

1.12e-0311922GO:0052629
GeneOntologyMolecularFunctionstructural constituent of postsynaptic density

SHANK1 DLG1

1.12e-0311922GO:0098919
GeneOntologyMolecularFunctionphosphatidylinositol-4,5-bisphosphate phosphatase activity

SYNJ1 SYNJ2

1.34e-0312922GO:0106019
GeneOntologyMolecularFunctionphosphatidylinositol phosphate 5-phosphatase activity

SYNJ1 SYNJ2

1.58e-0313922GO:0034595
GeneOntologyMolecularFunctionstructural constituent of postsynaptic specialization

SHANK1 DLG1

1.58e-0313922GO:0098879
GeneOntologyMolecularFunctioninositol trisphosphate phosphatase activity

SYNJ1 SYNJ2

1.84e-0314922GO:0046030
GeneOntologyMolecularFunctionphosphatidylinositol-3-phosphate phosphatase activity

SYNJ1 SYNJ2

1.84e-0314922GO:0004438
GeneOntologyMolecularFunctionphosphatidylinositol monophosphate phosphatase activity

SYNJ1 SYNJ2

2.12e-0315922GO:0052744
GeneOntologyMolecularFunctionN6-methyladenosine-containing RNA reader activity

RBM33 YTHDF3

2.12e-0315922GO:1990247
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate phosphatase activity

SYNJ1 SYNJ2

2.42e-0316922GO:0106018
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRM PTPRU

2.73e-0317922GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRM PTPRU

2.73e-0317922GO:0019198
DomainZinc_finger_PHD-type_CS

BAZ1A CHD5 PHF14 CHD4 PHF21A

1.45e-0565895IPR019786
DomainDUF1866

SYNJ1 SYNJ2

2.25e-052892IPR015047
DomainDUF1866

SYNJ1 SYNJ2

2.25e-052892SM01165
DomainDUF1866

SYNJ1 SYNJ2

2.25e-052892PF08952
DomainPHD

BAZ1A CHD5 PHF14 CHD4 PHF21A

2.91e-0575895PF00628
DomainZnf_PHD-finger

BAZ1A CHD5 PHF14 CHD4 PHF21A

3.75e-0579895IPR019787
DomainMAM_1

PTPRM PTPRU EGFL6

5.60e-0516893PS00740
DomainPHD

BAZ1A CHD5 PHF14 CHD4 PHF21A

6.64e-0589895SM00249
DomainCHDCT2

CHD5 CHD4

6.72e-053892PF08074
DomainCHDNT

CHD5 CHD4

6.72e-053892PF08073
DomainDUF1086

CHD5 CHD4

6.72e-053892IPR009462
DomainDUF1087

CHD5 CHD4

6.72e-053892IPR009463
DomainCHD_N

CHD5 CHD4

6.72e-053892IPR012958
DomainCHD_C2

CHD5 CHD4

6.72e-053892IPR012957
DomainDUF1087

CHD5 CHD4

6.72e-053892PF06465
DomainDUF1086

CHD5 CHD4

6.72e-053892PF06461
DomainDUF1087

CHD5 CHD4

6.72e-053892SM01147
DomainDUF1086

CHD5 CHD4

6.72e-053892SM01146
DomainMAM

PTPRM PTPRU EGFL6

6.78e-0517893SM00137
DomainZnf_PHD

BAZ1A CHD5 PHF14 CHD4 PHF21A

7.39e-0591895IPR001965
DomainMAM

PTPRM PTPRU EGFL6

8.10e-0518893PF00629
DomainMAM_dom

PTPRM PTPRU EGFL6

8.10e-0518893IPR000998
DomainMAM_2

PTPRM PTPRU EGFL6

8.10e-0518893PS50060
DomainZF_PHD_2

BAZ1A CHD5 PHF14 CHD4 PHF21A

9.07e-0595895PS50016
DomainZF_PHD_1

BAZ1A CHD5 PHF14 CHD4 PHF21A

9.53e-0596895PS01359
DomainRRM_dom

SETD1A ENOX1 SYNJ1 SYNJ2 RBM33 SCAF8 RBM42

1.06e-04227897IPR000504
DomainRRM

SETD1A ENOX1 SYNJ1 SYNJ2 RBM33 SCAF8 RBM42

1.15e-04230897PS50102
Domain-

SETD1A ENOX1 SYNJ1 SYNJ2 RBM33 SCAF8 RBM42

1.65e-042448973.30.70.330
DomainDUF3504

ZMYM2 ZMYM4

2.22e-045892IPR021893
DomainSyja_N

SYNJ1 SYNJ2

2.22e-045892PF02383
DomainSAC

SYNJ1 SYNJ2

2.22e-045892PS50275
DomainDUF3504

ZMYM2 ZMYM4

2.22e-045892PF12012
DomainSAC_dom

SYNJ1 SYNJ2

2.22e-045892IPR002013
DomainNucleotide-bd_a/b_plait

SETD1A ENOX1 SYNJ1 SYNJ2 RBM33 SCAF8 RBM42

2.33e-04258897IPR012677
DomainDCX

DCDC2 DCLK2

3.33e-046892SM00537
Domain-

DCDC2 DCLK2

4.64e-0478923.10.20.230
DomainDCX

DCDC2 DCLK2

4.64e-047892PF03607
DomainZnf_MYM

ZMYM2 ZMYM4

4.64e-047892IPR010507
Domainzf-FCS

ZMYM2 ZMYM4

4.64e-047892PF06467
DomainTRASH_dom

ZMYM2 ZMYM4

6.17e-048892IPR011017
DomainTRASH

ZMYM2 ZMYM4

6.17e-048892SM00746
DomainDC

DCDC2 DCLK2

6.17e-048892PS50309
DomainDoublecortin_dom

DCDC2 DCLK2

6.17e-048892IPR003533
DomainZnf_FYVE_PHD

BAZ1A CHD5 PHF14 CHD4 PHF21A

6.89e-04147895IPR011011
DomainSH3_2

SHANK1 SASH1 SH3D19 DLG1

7.60e-0486894IPR011511
DomainSH3_2

SHANK1 SASH1 SH3D19 DLG1

7.60e-0486894PF07653
DomainIPPc

SYNJ1 SYNJ2

9.86e-0410892IPR000300
DomainIPPc

SYNJ1 SYNJ2

9.86e-0410892SM00128
DomainPost-SET_dom

SETD1A SETD2

2.58e-0316892IPR003616
DomainPostSET

SETD1A SETD2

2.58e-0316892SM00508
DomainPOST_SET

SETD1A SETD2

2.58e-0316892PS50868
DomainSH3

SHANK1 SASH1 SH3D19 BTK DLG1

3.73e-03216895SM00326
DomainSH3

SHANK1 SASH1 SH3D19 BTK DLG1

3.73e-03216895PS50002
DomainRRM

SETD1A ENOX1 RBM33 SCAF8 RBM42

3.81e-03217895SM00360
DomainConA-like_dom

PTPRM COL27A1 LAMA2 PTPRU EGFL6

3.96e-03219895IPR013320
DomainSH3_domain

SHANK1 SASH1 SH3D19 BTK DLG1

4.04e-03220895IPR001452
DomainSAM_1

SHANK1 SGMS1 SASH1

4.19e-0368893PF00536
DomainChromo_domain

CHD5 CHD4

5.79e-0324892IPR023780
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SETD1A SETD2 CDV3 BRD8 RAPH1 SYNJ1 SH3D19 MDC1 LPP YLPM1 GIGYF2 DLG1 TAF4 PC ZYX ZMYM4

1.49e-12549931638280479
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SETD2 BRD8 SFSWAP PAPOLA RAPH1 SCAF8 MDC1 YLPM1 ZMYM2 GIGYF2 DLG1 PHF14 CHD4 RRBP1 HSF1 ZYX ZMYM4 SON

2.26e-12774931815302935
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ZNF512B SETD2 BRD8 SFSWAP MBNL2 RBM33 BAZ1A MDC1 YLPM1 ZMYM2 GIGYF2 PHF14 CHD4 TAF4 RRBP1 PC ZMYM4 YTHDF3 SON

7.55e-12954931936373674
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ZNF512B SETD2 CDV3 PAPOLA RAPH1 SYNJ1 BAZ1A SH3D19 LPP YLPM1 ZMYM2 GIGYF2 CHD4 RRBP1 PC ZYX PHF21A SON

4.93e-11934931833916271
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CASC3 VPS13D SASH1 FAM171A2 RAPH1 SYNJ1 SYNJ2 SH3D19 LPP MAP3K14 FAM83G GIGYF2 DCLK2 PC ZYX MTSS2

1.12e-09861931636931259
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ZNF512B SETD2 MYPOP BRD8 SFSWAP BAZ1A MDC1 YLPM1 RBM42 ZMYM2 PHF14 CHD4 TAF4 RRBP1 PC MNT ZMYM4 PHF21A SON

1.28e-091294931930804502
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CASC3 SETD2 MGAT1 BRD8 DIMT1 SFSWAP RBM33 BAZ1A SCAF8 CRACDL MDC1 BMS1 RBM42 ZMYM2 DLG1 PHF14 TAF4 ZMYM4 MAN1B1 SON

2.22e-091497932031527615
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SHANK1 CASC3 FAM171A2 SYNJ1 NHSL2 SH3D19 KSR2 YLPM1 ADGRB2 PAK1 ZMYM2 GIGYF2 DLG1 CHD4 TAF4 MTSS2

5.48e-09963931628671696
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

BRD8 MDC1 ZMYM2 PHF14 CHD4 TAF4 ZMYM4 PHF21A

7.41e-0915093828242625
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

CDV3 LPP PAK1 ZMYM2 TAF4 HSF1 PC ZYX ZMYM4 YTHDF3 PHF21A

3.09e-08444931134795231
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF512B SETD1A SASH1 SYNJ2 CHD5 MDC1 BMS1 RRBP1 KDM6B ZMYM4 PHF21A

1.80e-07529931114621295
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

ZNF512B CHD5 ZMYM2 PHF14 CHD4 ZMYM4

3.60e-0710393632744500
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

ZMAT3 BAZ1A MDC1 ZMYM2 CHD4 ZMYM4

4.27e-0710693619394292
Pubmed

Interaction network of human early embryonic transcription factors.

ZNF512B SETD1A BAZ1A MDC1 ZMYM2 TAF4 ZMYM4 YTHDF3 PHF21A

4.48e-0735193938297188
Pubmed

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.

RAPH1 SYNJ1 SYNJ2 SH3D19 DAG1 FAM83G

4.77e-0710893619531213
Pubmed

Functional proteomics mapping of a human signaling pathway.

ZNF512B MGAT1 SASH1 PAPOLA BAZ1A HIPK1 YLPM1 ZMYM2 RRBP1 ZYX SON

5.39e-07591931115231748
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

ZNF512B BRD8 RBM33 MDC1 YLPM1 ZMYM2 CHD4 PHF21A

6.48e-0726893833640491
Pubmed

A human MAP kinase interactome.

SHANK1 SYNJ2 RBM33 HIPK1 SH3D19 BTK PAK1 ZMYM2 GIGYF2 ZYX

7.43e-07486931020936779
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

BRD8 PAPOLA RAPH1 SYNJ1 RBM33 MDC1 YLPM1 CHD4 ZYX SON

1.07e-06506931030890647
Pubmed

Human transcription factor protein interaction networks.

ZNF512B SETD1A BRD8 RBM33 SCAF8 CHD5 MDC1 YLPM1 BMS1 ZMYM2 GIGYF2 TAF4 MNT ZMYM4 YTHDF3 PHF21A

1.17e-061429931635140242
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SHANK1 ZNF512B SYNJ1 HIPK1 SH3D19 YLPM1 PAK1 ZMYM2 DLG1 DCLK2 CHD4 RRBP1 KDM6B PC ZMYM4

1.58e-061285931535914814
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

ZNF512B TBC1D10C DIMT1 SFSWAP BAZ1A MDC1 BMS1 GIGYF2 CHD4 ZMYM4 YTHDF3 SON

2.76e-06847931235850772
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

RAPH1 SYNJ1 SYNJ2 SPRR3 SH3D19 LPP DAG1 GIGYF2 DLG1 ZYX

2.86e-06565931025468996
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

CASC3 SETD2 SYNJ2 RBM33 SCAF8 MDC1 LPP YLPM1 DLG1 RRBP1 YTHDF3

4.30e-06733931134672954
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ZNF512B FAM171A2 RAPH1 PTPRM LPP YLPM1 BMS1 DLG1 LTBP1 PTPRU PC CNTROB ZYX

4.43e-061049931327880917
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

CASC3 BAZ1A MDC1 BMS1 ZMYM2 PHF14 CHD4 ZMYM4

4.61e-0634993825665578
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

CDV3 DIMT1 RAPH1 SCAF8 MDC1 LPP PGLS GIGYF2 CHD4 RRBP1 HSF1 PC YTHDF3 MAN1B1 SON

5.09e-061415931528515276
Pubmed

The extracellular matrix protein laminin α2 regulates the maturation and function of the blood-brain barrier.

LAMA2 DAG1

7.07e-06293225392494
Pubmed

The Synaptojanins in the murine small and large intestine.

SYNJ1 SYNJ2

7.07e-06293227878645
Pubmed

Both laminin and Schwann cell dystroglycan are necessary for proper clustering of sodium channels at nodes of Ranvier.

LAMA2 DAG1

7.07e-06293216221851
Pubmed

Developmentally regulated alternative splicing in a novel synaptojanin.

SYNJ1 SYNJ2

7.07e-0629329442075
Pubmed

Epigenotype-genotype-phenotype correlations in SETD1A and SETD2 chromatin disorders.

SETD1A SETD2

7.07e-06293237166351
Pubmed

Dystroglycan is a dual receptor for agrin and laminin-2 in Schwann cell membrane.

LAMA2 DAG1

7.07e-0629328798547
Pubmed

Identification of alpha-dystroglycan binding sequences in the laminin alpha2 chain LG4-5 module.

LAMA2 DAG1

7.07e-06293219800000
Pubmed

Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages.

LAMA2 DAG1

7.07e-06293217389231
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CASC3 SGMS1 MBNL2 SYNJ2 SCAF8 LPP KSR2 DLG1 PHF14 ANKMY1 DCLK2 TAF4 RRBP1 ZMYM4 MAN1B1

9.36e-061489931528611215
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZMAT3 BRD8 MBNL2 BAZ1A LPP ZMYM2 PHF14 HSF1 MNT ZYX PHF21A

1.07e-05808931120412781
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

SETD2 SFSWAP RBM33 MDC1 YLPM1 PGLS ZYX SON

1.22e-0539993835987950
Pubmed

Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.

BAZ1A CHD4 TAF4 PHF21A

1.27e-055393436841324
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

VPS13D SGMS1 MBNL2 SH3D19 LPP DAG1 DLG1 HSF1 PHF21A

1.40e-0553693915840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

VPS13D SGMS1 MBNL2 SH3D19 LPP DAG1 DLG1 HSF1 PHF21A

1.44e-0553893910512203
Pubmed

A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.

ZMYM2 CHD4 PHF21A

1.47e-051893312493763
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RAPH1 SYNJ1 ZMYM2 GIGYF2 CHD4 PC ZMYM4 PHF21A

1.70e-0541893834709266
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOXB1 BRD8 BAZ1A HIPK1 BMS1 ZMYM2 CHD4 RRBP1 MNT ZMYM4 PHF21A

1.85e-05857931125609649
Pubmed

Distribution of dystroglycan in normal adult mouse tissues.

LAMA2 DAG1

2.12e-0539329524190
Pubmed

α-Dystroglycan is essential for the induction of Egr3, a transcription factor important in muscle spindle formation.

EGR3 DAG1

2.12e-05393220213761
Pubmed

Dystroglycan is not required for localization of dystrophin, syntrophin, and neuronal nitric-oxide synthase at the sarcolemma but regulates integrin alpha 7B expression and caveolin-3 distribution.

LAMA2 DAG1

2.12e-05393211741881
Pubmed

Transcriptional activation of the anchoring protein SAP97 by heat shock factor (HSF)-1 stabilizes K(v) 1.5 channels in HL-1 cells.

DLG1 HSF1

2.12e-05393221232033
Pubmed

Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice.

LAMA2 DAG1

2.12e-0539321757468
Pubmed

Dystroglycan is a binding protein of laminin and merosin in peripheral nerve.

LAMA2 DAG1

2.12e-0539327925941
Pubmed

Laminin alpha1 chain mediated reduction of laminin alpha2 chain deficient muscular dystrophy involves integrin alpha7beta1 and dystroglycan.

LAMA2 DAG1

2.12e-05393216504180
Pubmed

Characterization of the zinc finger proteins ZMYM2 and ZMYM4 as novel B-MYB binding proteins.

ZMYM2 ZMYM4

2.12e-05393232439918
Pubmed

Brain alpha-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11.

LAMA2 DAG1

2.12e-05393216709410
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

CDV3 MBNL2 SYNJ2 RBM33 YLPM1 GIGYF2 RRBP1 ZYX YTHDF3 SON

2.45e-05724931036232890
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

SYNJ1 PTPRM MBNL2 DLG1 PHF21A

2.50e-0512893530995482
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DCDC2 SYNJ1 CHD5 GIGYF2 RRBP1 ARHGEF15

3.27e-0522593612168954
Pubmed

Tagging genes with cassette-exchange sites.

ENOX1 SFSWAP SCAF8 GIGYF2 TAF4 MNT ZMYM4

3.37e-0533593715741177
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

ZNF512B SETD2 MBNL2 SCAF8 MDC1 CHD4 HSF1 CNTROB ZMYM4 ARHGEF15

3.46e-05754931035906200
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

ZNF512B SFSWAP BAZ1A CHD5 MDC1 YLPM1 BMS1 PHF14 CHD4

3.61e-0560593928977666
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

BRD8 SGMS1 PAPOLA RAPH1 BAZ1A ADGRB2 GIGYF2 DCLK2 CHD4 PTPRU CNTROB

3.72e-05925931128986522
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZNF512B BAZ1A CHD5 MDC1 ZMYM2 PHF14 CHD4 TAF4 ZMYM4

3.75e-0560893936089195
Pubmed

Dystroglycan is essential for early embryonic development: disruption of Reichert's membrane in Dag1-null mice.

LAMA2 DAG1

4.23e-0549329175728
Pubmed

Differential expression of MAM-subfamily protein tyrosine phosphatases during mouse development.

PTPRM PTPRU

4.23e-0549329510027
Pubmed

Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions.

LPP ZYX

4.23e-05493222665060
Pubmed

The SAC domain-containing protein gene family in Arabidopsis.

SYNJ1 SYNJ2

4.23e-05493212805586
Pubmed

Molecular recognition by LARGE is essential for expression of functional dystroglycan.

LAMA2 DAG1

4.23e-05493215210115
Pubmed

An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.

LAMA2 DAG1

4.23e-05493211565031
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

RBM33 MDC1 YLPM1 CHD4 SON

5.01e-0514893532538781
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

SETD2 CDV3 BRD8 DIMT1 YLPM1 PGLS GIGYF2 PHF14 LTBP1 TAF4 PC MNT ZMYM4

5.22e-051327931332694731
Pubmed

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.

CC2D2A LTBP1 MTSS2

5.78e-052893333953184
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

CASC3 DIMT1 MBNL2 RBM33 YLPM1 BMS1 GIGYF2 RRBP1 YTHDF3 SON

6.10e-05807931022681889
Pubmed

JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during Spermatogenesis.

BAZ1A CHD5 MDC1

6.43e-052993327649575
Pubmed

A laminin-2, dystroglycan, utrophin axis is required for compartmentalization and elongation of myelin segments.

LAMA2 DAG1

7.04e-05593219321787
Pubmed

Overexpression of LARGE suppresses muscle regeneration via down-regulation of insulin-like growth factor 1 and aggravates muscular dystrophy in mice.

LAMA2 DAG1

7.04e-05593224722207
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

SETD2 BRD8 PAPOLA BAZ1A MDC1 YLPM1 PHF14 CHD4 TAF4 RRBP1 SON

8.45e-051014931132416067
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

BRD8 ZMYM2 CHD4 TAF4 ZMYM4

8.88e-0516793520362541
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

CHD5 MDC1 ZMYM2 PHF14 CHD4 RRBP1

9.15e-0527193632433965
Pubmed

Absence of post-phosphoryl modification in dystroglycanopathy mouse models and wild-type tissues expressing non-laminin binding form of α-dystroglycan.

LAMA2 DAG1

1.05e-04693222270369
Pubmed

The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins.

SHANK1 ADGRB2

1.05e-04693210964907
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYPOP RAPH1 BAZ1A NHSL2 CHD5 YLPM1 RBM42 CC2D2A DLG1 PHF14 CHD4 TAF4 RRBP1

1.20e-041442931335575683
Pubmed

The functional interactome landscape of the human histone deacetylase family.

ZNF512B YLPM1 ZMYM2 CHD4 PHF21A SON

1.30e-0428993623752268
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

SHANK1 CASC3 SETD2 ADGRB2 CHRD LTBP1 CNTROB ADAMTSL4

1.32e-0456093821653829
Pubmed

Transmembrane homodimerization of receptor-like protein tyrosine phosphatases.

PTPRM PTPRU

1.47e-04793215978577
Pubmed

Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.

MGAT1 LPP

1.47e-04793219851299
Pubmed

Distinct alpha 7A beta 1 and alpha 7B beta 1 integrin expression patterns during mouse development: alpha 7A is restricted to skeletal muscle but alpha 7B is expressed in striated muscle, vasculature, and nervous system.

LAMA2 DAG1

1.47e-0479328950511
Pubmed

Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice.

LAMA2 DAG1

1.47e-04793211802174
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

CASC3 CDV3 BRD8 SFSWAP RBM33 TAF4 RRBP1

1.49e-0442593724999758
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

DCDC2 BRD8 SGMS1 PAPOLA SYNJ1 BAZ1A LPP DAG1 DLG1 YTHDF3 MAN1B1

1.52e-041084931111544199
Pubmed

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.

COL27A1 FAM83G ADAMTSL4 ARHGEF15

1.54e-0410093426073538
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

ZNF512B CASC3 SETD1A ENOX1 SFSWAP YLPM1 DAG1 GIGYF2 PHF14 YTHDF3

1.81e-04922931027609421
Pubmed

Caveolin-3 deficiency causes muscle degeneration in mice.

LAMA2 DAG1

1.96e-04893211115849
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMA2 DAG1

1.96e-0489328872465
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

SCAF8 MDC1 ZMYM2 GIGYF2 CHD4

2.21e-0420393522083510
Pubmed

A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.

SHANK1 BRD8 DLG1

2.26e-044493332492419
Pubmed

Transcriptome analysis of human gastric cancer.

CDV3 DIMT1 ENOX1 SGMS1 SH3D19 PHF14 MNT ZYX MAN1B1

2.28e-0477293916341674
Pubmed

The histone demethylase LSD1/KDM1A promotes the DNA damage response.

MDC1 PHF21A

2.52e-04993224217620
Pubmed

Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers.

ZYX SON

2.52e-04993211782456
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

DIMT1 CHD5 BMS1 PHF14 CHD4 SON

2.66e-0433093633301849
Pubmed

The doublecortin gene family and disorders of neuronal structure.

DCDC2 DCLK2

3.14e-041093220236041
Pubmed

The evolving doublecortin (DCX) superfamily.

DCDC2 DCLK2

3.14e-041093216869982
InteractionNAA40 interactions

ZNF512B FOXB1 SETD2 CDV3 PAPOLA RAPH1 SYNJ1 BAZ1A SH3D19 LPP YLPM1 ZMYM2 GIGYF2 CHD4 RRBP1 PC ZYX PHF21A SON

5.98e-089789119int:NAA40
InteractionSMC5 interactions

ZNF512B SETD2 BRD8 SFSWAP MBNL2 RBM33 BAZ1A MDC1 YLPM1 ZMYM2 GIGYF2 PHF14 CHD4 TAF4 RRBP1 PC ZMYM4 YTHDF3 SON

8.48e-0810009119int:SMC5
InteractionPML interactions

CDV3 BRD8 HIPK1 MDC1 LPP PAK1 ZMYM2 CHD4 TAF4 RRBP1 HSF1 PC ZYX ZMYM4 YTHDF3 MAN1B1 PHF21A

8.10e-079339117int:PML
InteractionFHL3 interactions

ZNF512B SETD1A MYPOP HIPK1 RBM42 ADAMTSL4 ZYX ZMYM4 PHF21A

4.37e-06276919int:FHL3
InteractionPCDHGB4 interactions

FAM171A2 TMEM132A DAG1 LTBP1 PTPRU

6.94e-0659915int:PCDHGB4
InteractionBMI1 interactions

CASC3 CDV3 ENOX1 MBNL2 BAZ1A SCAF8 YLPM1 GIGYF2 CHD4 RRBP1 YTHDF3 MAN1B1 SON

7.99e-066599113int:BMI1
InteractionYWHAG interactions

KIAA0408 CASC3 VPS13D SASH1 FAM171A2 RAPH1 SYNJ1 SYNJ2 BAZ1A NHSL2 SH3D19 KSR2 PAK1 FAM83G GIGYF2 DCLK2 SON MTSS2

9.96e-0612489118int:YWHAG
InteractionSH3KBP1 interactions

PAPOLA RAPH1 SYNJ1 SYNJ2 SH3D19 MDC1 PAK1 DAG1 FAM83G

1.27e-05315919int:SH3KBP1
InteractionDUXA interactions

ZNF512B BAZ1A MDC1

1.90e-0512913int:DUXA
InteractionNUP43 interactions

SETD1A SETD2 BRD8 BAZ1A MDC1 BMS1 PGLS ZMYM2 TAF4 ZMYM4 PHF21A SON

2.40e-056259112int:NUP43
InteractionYAP1 interactions

SETD1A SETD2 CDV3 BRD8 PAPOLA SH3D19 MDC1 YLPM1 GIGYF2 DLG1 CHD4 TAF4 RRBP1 PC ZYX ZMYM4

2.86e-0510959116int:YAP1
InteractionYWHAH interactions

CASC3 VPS13D SASH1 SFSWAP FAM171A2 SYNJ1 SYNJ2 NHSL2 SH3D19 LPP KSR2 FAM83G CC2D2A GIGYF2 DCLK2 MTSS2

3.09e-0511029116int:YWHAH
InteractionYY1 interactions

ZNF512B SETD1A FOXB1 BRD8 MDC1 ZMYM2 TAF4 ZMYM4 ARHGEF15 MTSS2

3.84e-054549110int:YY1
InteractionCDH1 interactions

GPR61 RAPH1 SYNJ1 PTPRM SYNJ2 SPRR3 SH3D19 LPP DAG1 GIGYF2 DLG1 CHD4 ZYX

3.99e-057689113int:CDH1
InteractionH3C1 interactions

ZNF512B SETD1A SETD2 BAZ1A MDC1 PAK1 LAMA2 ZMYM2 CHD4 TAF4 RRBP1 KDM6B HSF1 ZMYM4

4.98e-059019114int:H3C1
InteractionMEN1 interactions

ZNF512B SETD1A FOXB1 DIMT1 PAPOLA BAZ1A MDC1 YLPM1 BMS1 ZMYM2 GIGYF2 CHD4 ZMYM4 YTHDF3 SON

5.40e-0510299115int:MEN1
InteractionSIN3B interactions

ZNF512B BRD8 CHD5 MDC1 MNT PHF21A

5.44e-05147916int:SIN3B
InteractionDUXB interactions

MDC1 ZMYM2 YTHDF3

6.92e-0518913int:DUXB
InteractionCHD4 interactions

ZNF512B SETD1A SFSWAP CHD5 MDC1 YLPM1 BMS1 ZMYM2 GIGYF2 PHF14 CHD4 RRBP1 HSF1 ZMYM4

7.68e-059389114int:CHD4
InteractionDCP1A interactions

RAPH1 LPP CNTROB ZYX YTHDF3 PHF21A

1.07e-04166916int:DCP1A
InteractionRTL9 interactions

BRD8 HSF1 ZMYM4

1.12e-0421913int:RTL9
InteractionKLF8 interactions

SETD1A BRD8 ZMYM2 TAF4 MNT ZMYM4 YTHDF3 PHF21A

1.21e-04329918int:KLF8
InteractionZYX interactions

ZNF512B PAPOLA SH3D19 LPP CNTROB ZYX YTHDF3 PHF21A

1.21e-04329918int:ZYX
InteractionPCDHGC5 interactions

TMEM132A LTBP1 PTPRU

1.29e-0422913int:PCDHGC5
InteractionLAMA2 interactions

LAMA2 DAG1 LTBP1

1.48e-0423913int:LAMA2
InteractionNUP50 interactions

ZNF512B SETD1A CDV3 SFSWAP RBM33 DLG1 TAF4 SON

1.55e-04341918int:NUP50
InteractionCBX3 interactions

ZNF512B SETD1A SETD2 CHD5 MDC1 ZMYM2 CHD4 TAF4 KDM6B ADAMTSL4 ZMYM4

1.56e-046469111int:CBX3
InteractionLPXN interactions

BTK LPP PAK1 ZYX PHF21A

1.74e-04115915int:LPXN
InteractionDZIP3 interactions

BAZ1A ZMYM2 CHD4 TAF4 YTHDF3 PHF21A

1.82e-04183916int:DZIP3
InteractionNCK2 interactions

KIAA0408 MYPOP RAPH1 NHSL2 YLPM1 PAK1 MNT

1.85e-04262917int:NCK2
InteractionH2BC9 interactions

SYNJ2 MDC1 YLPM1 LAMA2 GIGYF2 CHD4 TAF4 RRBP1 EGFL6

1.85e-04446919int:H2BC9
InteractionTERF2IP interactions

ZNF512B SETD1A SETD2 BRD8 SFSWAP MDC1 PGLS ZMYM2 TAF4 ZMYM4

1.93e-045529110int:TERF2IP
InteractionGBX2 interactions

GBX1 CHD4

2.00e-045912int:GBX2
InteractionDOT1L interactions

ZNF512B TBC1D10C DIMT1 SFSWAP BAZ1A MDC1 BMS1 GIGYF2 CHD4 ZMYM4 YTHDF3 SON

2.71e-048079112int:DOT1L
InteractionH2BC8 interactions

ZNF512B BRD8 PAPOLA BAZ1A MDC1 BMS1 ZMYM2 PHF14 CHD4 ZMYM4

2.71e-045769110int:H2BC8
InteractionACTC1 interactions

BRD8 PAPOLA RAPH1 SYNJ1 RBM33 MDC1 YLPM1 CHD4 ZYX ZMYM4 SON

2.89e-046949111int:ACTC1
GeneFamilyPHD finger proteins

BAZ1A CHD5 PHF14 CHD4 PHF21A

1.11e-059059588
GeneFamilyZinc fingers MYM-type

ZMYM2 ZMYM4

1.56e-04659286
GeneFamilyDoublecortin superfamily

DCDC2 DCLK2

4.63e-04105921369
GeneFamilyRNA binding motif containing

SETD1A ENOX1 RBM33 SCAF8 RBM42

6.47e-04213595725
GeneFamilyPHD finger proteins|NuRD complex

CHD5 CHD4

6.77e-04125921305
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRM PTPRU

2.11e-0321592813
GeneFamilySterile alpha motif domain containing

SHANK1 SGMS1 SASH1

2.98e-0388593760
GeneFamilyPhosphoinositide phosphatases

SYNJ1 SYNJ2

4.88e-03325921079
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD1A SETD2

5.49e-0334592487
GeneFamilyFibronectin type III domain containing

PTPRM PTPRU TNXB

1.54e-02160593555
GeneFamilyLIM domain containing

LPP ZYX

1.59e-02595921218
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SETD2 SGMS1 SASH1 PTPRM SYNJ2 BAZ1A SCAF8 MAP3K14 ZMYM2 GIGYF2 DLG1 PHF14 TAF4 MNT ZMYM4 YTHDF3 PHF21A SON

1.09e-098569318M4500
CoexpressionGSE21033_CTRL_VS_POLYIC_STIM_DC_1H_DN

CDV3 SFSWAP SYNJ1 BAZ1A TAF4 KDM6B ZYX

6.91e-06198937M7716
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN

SGMS1 PTPRM SYNJ2 PHF14 SON

1.25e-0584935M13008
CoexpressionGINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN

SETD1A MYPOP SFSWAP RBM33 ARHGAP30 CNTROB PHF21A MTSS2

2.77e-05338938M17094
CoexpressionRAPA_EARLY_UP.V1_UP

CHD5 ADGRB2 CHRD PIGO ARHGEF15 ITPKA

2.95e-05167936M2644
CoexpressionNAKAYA_B_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_UP

MBNL2 SYNJ2 BAZ1A MDC1 YLPM1 PAK1 ANKMY1 TNXB

4.95e-05367938M41159
CoexpressionAIZARANI_LIVER_C39_EPCAM_POS_BILE_DUCT_CELLS_4

DCDC2 SYNJ2 BAZ1A RRBP1 KDM6B ZYX

5.07e-05184936M39135
CoexpressionGSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_0.5H_ACT_CD4_TCELL_DN

LRRC63 FOXB1 CRACDL FAM83G ADAMTSL4 ITPKA

5.38e-05186936M4207
CoexpressionGSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN

CDV3 SGMS1 CHRD TAF4 ZYX MTSS2

7.61e-05198936M7708
CoexpressionGSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_UP

CDV3 SGMS1 MAP3K14 PHF14 TAF4 KDM6B

7.61e-05198936M7684
CoexpressionGSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN

SCAF8 DAG1 ZMYM2 GIGYF2 HSF1 PHF21A

8.04e-05200936M9765
CoexpressionGSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN

CDV3 MGAT1 BAZ1A LPP MAP3K14 MNT

8.04e-05200936M6095
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SYNJ2 EGR3 CRACDL TMEM132A ADGRB2 DLG1 ITPKA

1.29e-0718693756c139e679d640ea901ead657a8e8887e0fca098
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

SETD2 HIPK1 GIGYF2 ANKMY1 CHD4 SON

1.35e-0616693632d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MBNL2 SYNJ2 NHSL2 CRACDL COL27A1 ITPKA

2.09e-061799369ba8693fba2175bca9ff9735cc04e657abeb9084
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KIAA0408 ADGRB2 LAMA2 CHRD TNXB EGFL6

3.13e-061929364ed5040594ba2d0639f0990697504ecef872ca70
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KIAA0408 ADGRB2 LAMA2 CHRD TNXB EGFL6

3.13e-06192936d4f5d6653564c2c5d0f5f7c932d89cb1b1412844
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SASH1 PTPRM SH3D19 LTBP1 ARHGEF15 PHF21A

3.22e-06193936e1d546165dcc2392f540162206852c4717d7306f
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NHSL2 COL27A1 SH3D19 LAMA2 LTBP1 TNXB

3.22e-06193936b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)|Neuronal / cells hierarchy compared to all cells using T-Statistic

MBNL2 SYNJ2 NHSL2 CRACDL COL27A1 ITPKA

3.96e-062009360f23e72649a274043bf23e0952a9b5707c516acf
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

SASH1 PTPRM EGR3 NHSL2 DCLK2

2.36e-05163935d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM33 HIPK1 CHD5 DCLK2 ARHGEF15

2.80e-051699354e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCelldroplet-Heart-4Chambers-18m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC63 BTK PAK1 ARHGAP30 KRT36

2.80e-05169935ea43002e74076aa03bf688c0a76c07117787d4b5
ToppCelldroplet-Heart-4Chambers-18m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC63 BTK PAK1 ARHGAP30 KRT36

2.97e-051719354935a95d11ac997d183fab32cbaad837bf0a512b
ToppCelldroplet-Heart-4Chambers-18m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC63 BTK PAK1 ARHGAP30 KRT36

3.05e-0517293519ccac3d88382b8b2379d14525b2204c7407cb3b
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM33 NHSL2 ZMYM4 ARHGEF15 MTSS2

3.50e-051779358ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EGR3 CRACDL ADGRB2 DLG1 ITPKA

3.89e-0518193558f76bb9ea1518c2b629a0256a3f6595a9278152
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENOX1 EGR3 COL27A1 LAMA2 KDM6B

3.89e-05181935ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHANK1 KIAA0408 COL27A1 LTBP1 TNXB

4.10e-051839357eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellfacs-Lung-EPCAM-24m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D10C PAK1 ARHGAP30 ZYX KRT36

4.10e-05183935b082fb7afab13106ddeb764fab4c32c485123f74
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNJ2 NHSL2 CRACDL COL27A1 ITPKA

4.10e-051839351645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

SH3D19 LAMA2 CHRD LTBP1 TNXB

4.21e-051849352b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ENOX1 SYNJ2 NHSL2 LAMA2 EGFL6

4.21e-05184935327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MBNL2 SYNJ2 CRACDL PAK1 DLG1

4.43e-0518693584ba666237c18189d7e7556bd92dd953af733c00
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBNL2 BAZ1A CHD4 KDM6B SON

4.54e-05187935663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBNL2 BAZ1A CHD4 KDM6B SON

4.66e-05188935d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

KIAA0408 COL27A1 LAMA2 TNXB EGFL6

4.78e-05189935eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

KIAA0408 COL27A1 LAMA2 TNXB EGFL6

4.78e-0518993540764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MBNL2 CRACDL ADGRB2 PAK1 DLG1

4.90e-05190935d594da827e3c16644952b9589cc12b947ce36279
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

KIAA0408 COL27A1 LAMA2 TNXB EGFL6

5.02e-051919355271198116343c07202649889057e5774d7fdde3
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

DCDC2 SYNJ2 RBM33 DLG1 RRBP1

5.15e-05192935916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NHSL2 SH3D19 LAMA2 LTBP1 TNXB

5.15e-0519293599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

SYNJ2 BAZ1A LPP MAP3K14 KDM6B

5.15e-051929358b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

DAG1 GIGYF2 DLG1 ZMYM4 SON

5.28e-05193935abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

DCDC2 COL27A1 SH3D19 DLG1 MTSS2

5.28e-05193935503a979328c68b096680b71359a26f02fafdff35
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

DCDC2 SYNJ2 RBM33 DLG1 RRBP1

5.28e-05193935e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

SASH1 PTPRM SH3D19 DCLK2 ARHGEF15

5.41e-0519493571ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBNL2 LPP LAMA2 DAG1 LTBP1

5.68e-0519693566d76249bd2770cdddff2c1fe59a016e95da2124
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

NHSL2 SH3D19 LAMA2 LTBP1 TNXB

5.68e-05196935bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBNL2 LPP LAMA2 DAG1 LTBP1

5.68e-051969359bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

EGR3 COL27A1 LPP DAG1 LTBP1

5.82e-0519793561749ccafeb938c310cff1de5ff924a1c794325a
ToppCellTracheal-10x3prime_v2-Stromal-Mesofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

EGR3 LPP LTBP1 TNXB MTSS2

5.82e-05197935d7cef7881abd807a679432766ced609a6efd1067
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

ENOX1 RAPH1 MBNL2 DCLK2 PC

5.82e-051979358545baf923ddf84c5ce9414a36d810603be52401
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ENOX1 NHSL2 LAMA2 LTBP1 TNXB

5.82e-0519793544673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

EGR3 COL27A1 LPP DAG1 LTBP1

5.82e-051979359d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellTracheal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

EGR3 LPP LTBP1 TNXB MTSS2

5.82e-0519793520a5958512bdb99daeb8f4d244df53e4f048f879
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

NHSL2 SH3D19 LAMA2 LTBP1 TNXB

5.96e-0519893526e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FOXB1 ENOX1 EGR3 PAK1 ZYX

5.96e-05198935fa5c15a656d4132950092919600e270f1fd79abf
ToppCellSigmoid-(5)_Dendritic_cell-(51)_cDC1|Sigmoid / shred on region, Cell_type, and subtype

ENOX1 LPP DCLK2 CNTROB MNT

6.25e-052009354ce0a2238c90622e41fd86ac4b7d82adf4af2c3b
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

KIAA0408 LPP LAMA2 LTBP1 EGFL6

6.25e-05200935f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell3'-Parenchyma_lung-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SH3D19 LAMA2 CHRD LTBP1 TNXB

6.25e-05200935ba5ed66b05caa1be0bbf8d54c4e72a782b8d9833
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SYNJ2 DAG1 FAM83G DCLK2 ARHGEF15

6.25e-05200935a8b59e6fe04271fef61db911a286b5c48438bb84
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK---L2|Neuronal / cells hierarchy compared to all cells using T-Statistic

MBNL2 SYNJ2 NHSL2 COL27A1 ITPKA

6.25e-052009356ebdae4438bc64c6620416f64a7e22fbca2664bf
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

KIAA0408 LPP LAMA2 LTBP1 EGFL6

6.25e-052009355ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK-|Neuronal / cells hierarchy compared to all cells using T-Statistic

MBNL2 SYNJ2 NHSL2 COL27A1 ITPKA

6.25e-05200935081ca331b56f85167acfc73af9d2e91f398f8c4d
ToppCellSigmoid-Dendritic_cell-cDC1|Sigmoid / Region, Cell class and subclass

ENOX1 LPP DCLK2 CNTROB MNT

6.25e-052009353523ec986e8c9e176e08836c974b1de8b56d8b16
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK--|Neuronal / cells hierarchy compared to all cells using T-Statistic

MBNL2 SYNJ2 NHSL2 COL27A1 ITPKA

6.25e-0520093566e2f3e2e9063f17b47621120eb6009405f69e7e
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ENOX1 NHSL2 LAMA2 LTBP1 TNXB

6.25e-052009353dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK|Neuronal / cells hierarchy compared to all cells using T-Statistic

MBNL2 SYNJ2 NHSL2 COL27A1 ITPKA

6.25e-05200935940892bea41fde567f138a896d151acccef03a6a
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMA2 LTBP1 RRBP1 TNXB

1.55e-0412993413cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1|Hippocampus / BrainAtlas - Mouse McCarroll V32

CRACDL PTPRU TNXB ITPKA

1.59e-04130934c70fb77324916d220d842a575558a8245c276599
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL27A1 BTK MAP3K14 ARHGAP30

2.68e-04149934406a5ccfedbf43543f0346ff7ef3ce1d15c38f29
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL27A1 BTK MAP3K14 ARHGAP30

2.68e-0414993434a3075af794052763fc7c4135f3031f89da5caa
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL27A1 BTK MAP3K14 ARHGAP30

2.68e-04149934be698ecce34ddbdf57d08082b71268934675e74e
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

COL27A1 BTK MAP3K14 ARHGAP30

2.68e-04149934183c77cc8f23b8406e7241a066cb684470002a3b
ToppCell367C-Fibroblasts-Fibroblast-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

SH3D19 LAMA2 LTBP1 TNXB

3.04e-04154934dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell367C-Fibroblasts-Fibroblast-D|367C / Donor, Lineage, Cell class and subclass (all cells)

SH3D19 LAMA2 LTBP1 TNXB

3.04e-041549344bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D10C CRACDL CHD5 ADGRB2

3.12e-0415593472a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Agmat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EGR3 BAZ1A CRACDL ITPKA

3.19e-0415693409e0702400570089d9012dcf94dfb4827c97e49d
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BTK MAP3K14 FAM83G ARHGAP30

3.19e-041569346f8622716bad4e505f241a2a4ef953bf3fc6dbfa
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BAZ1A SCAF8 PAK1 ARHGAP30

3.19e-041569348349604bd801e20d33770f7d8243598c3756302b
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DCDC2 ADGRB2 CC2D2A AK9

3.27e-04157934410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

NHSL2 COL27A1 LAMA2 TNXB

3.43e-041599343f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

ADGRB2 CHRD DCLK2 EGFL6

3.52e-04160934fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellAdult-Mesenchymal-myofibroblast_cell-D175|Adult / Lineage, Cell type, age group and donor

SYNJ2 LAMA2 LTBP1 TNXB

3.60e-04161934048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCellfacs-Heart-LA-24m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EGR3 KDM6B ZYX KRT36

3.60e-04161934248487415a0601d57ef2a6692e22a61368d0b9c8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EGR3 BAZ1A CRACDL ITPKA

3.60e-04161934e3327c296d48e821004e61a573abb75624a6f040
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNJ2 EGR3 DCLK2 KDM6B

3.60e-0416193478cc5bc488bc47726195a649946d414e6bfabf94
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASC3 SFSWAP CHD5 ZMYM4

3.77e-04163934953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

SYNJ2 LAMA2 LTBP1 TNXB

4.13e-04167934d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

EGR3 ADGRB2 LTBP1 DCLK2

4.13e-04167934c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)|Hippocampus / BrainAtlas - Mouse McCarroll V32

EGR3 CRACDL CHRD ITPKA

4.23e-041689346db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCellAdult-Mesenchymal-chondrocyte-D175|Adult / Lineage, Cell type, age group and donor

NHSL2 COL27A1 LAMA2 TNXB

4.23e-0416893414071b961c9bdb54a8259b12a88237b802cbde36
ToppCellfacs-GAT-Fat-18m-Myeloid-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNJ1 PAK1 ARHGAP30 KDM6B

4.32e-041699347a7416fcbffcf57d19b477d9da091e04e3499524
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6|TCGA-Liver / Sample_Type by Project: Shred V9

SASH1 LAMA2 DCLK2 TNXB

4.32e-04169934e992530776cab922d0360b275fb9cb8bd0017b06
ToppCellfacs-GAT-Fat-18m-Myeloid|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNJ1 PAK1 ARHGAP30 KDM6B

4.32e-041699340e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCellfacs-GAT-Fat-18m-Myeloid-myeloid_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNJ1 PAK1 ARHGAP30 KDM6B

4.32e-041699349bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNJ2 LAMA2 LTBP1 TNXB

4.42e-04170934fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNJ2 LAMA2 LTBP1 TNXB

4.42e-0417093403044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell356C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF512B SCAF8 SH3D19 RRBP1

4.52e-041719343d26ef58fe5231373d7df9ac79d225546918cf82
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

ADGRB2 LTBP1 DCLK2 EGFL6

4.62e-04172934c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BAZ1A CHD5 BTK ARHGAP30

4.72e-04173934279efbab7810fa60ab12ea5d09a84800df4adef0
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR61 YLPM1 FAM83G PC

4.83e-04174934f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL2 CRACDL LAMA2 ITPKA

4.83e-041749349cc7251661ea2b1565eef1dfb8cf6dec3ade13d4
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CRACDL AK9 C2orf81

4.83e-04174934179a52d77899a929396b98d4ab2c270dd2ec708e
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CRACDL AK9 C2orf81

4.83e-041749349165a1094d345328e58962f4b2a20334c3e93ead
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LPP LAMA2 LTBP1 TNXB

4.93e-041759341799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SETD1A NHSL2 MDC1 KRT36

4.93e-0417593443be63976da5ad0764d24d90919a77ce46068f52
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BRD8 COL27A1 POU6F1 PC

4.93e-04175934aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NHSL2 TMEM132A LAMA2 LTBP1

5.04e-041769349bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHSL2 CRACDL COL27A1 ITPKA

5.04e-0417693407abf29d681abdd6c7cc87f9eaf9377e92ce212c
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 PTPRM COL27A1 LPP

5.04e-041769347292e014b8f697f0c2e9f47c48333de95cb44a69
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ZNF512B SETD2 SFSWAP PAPOLA SYNJ2 YLPM1 ZMYM2 DLG1 CHD4 RRBP1 SON

2.90e-1018793114302_DN
DrugMeclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A

ZNF512B SETD2 SYNJ2 YLPM1 TMEM132A PTPRU RRBP1 KDM6B

1.66e-062009383405_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

SYNJ1 BAZ1A SCAF8 GIGYF2 TAF4 PHF21A SON

9.86e-061829373887_DN
DrugClofazimine [2030-63-9]; Up 200; 8.4uM; PC3; HT_HG-U133A

ENOX1 SPRR3 TMEM132A LAMA2 RRBP1 KDM6B HSF1

1.54e-051959374682_UP
DrugIobenguane sulfate; Down 200; 10.8uM; HL60; HG-U133A

SETD2 VPS13D CDV3 MBNL2 BTK BMS1 DLG1

1.60e-051969371729_DN
DrugKanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; HL60; HG-U133A

ZNF512B SYNJ2 EGR3 LPP ANKMY1 RRBP1 SON

1.65e-051979371609_UP
DrugHA-1077 dihydrochloride; Up 200; 10uM; MCF7; HG-U133A

SETD2 VPS13D MBNL2 EGR3 YLPM1 MNT SON

1.70e-05198937343_UP
Drug0316684-0000 [391209-55-5]; Down 200; 10uM; MCF7; HT_HG-U133A

CDV3 SFSWAP EGR3 DAG1 DLG1 RRBP1 ZYX

1.70e-051989377093_DN
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; HL60; HT_HG-U133A

ZNF512B SETD1A VPS13D SGMS1 ANKMY1 KDM6B PIGO

1.70e-051989372346_DN
Drugirinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A

SGMS1 MBNL2 SCAF8 ZMYM2 GIGYF2 PHF21A

7.30e-051719367535_DN
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; PC3; HT_HG-U133A

SGMS1 LPP YLPM1 DAG1 ZMYM2 SON

8.83e-051779364652_DN
Drug5224221; Down 200; 12uM; MCF7; HT_HG-U133A_EA

ZNF512B ZMAT3 SYNJ2 EGR3 RRBP1 SON

9.69e-05180936956_DN
Drugwortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA

BRD8 SASH1 SYNJ2 YLPM1 MAP3K14 PHF21A

1.09e-041849361081_UP
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

DIMT1 SYNJ1 ZMYM2 DLG1 CHD4 SON

1.27e-041899361045_DN
DrugFlunisolide [3385-03-3]; Down 200; 9.2uM; PC3; HT_HG-U133A

SETD2 MBNL2 LPP ZMYM2 CHD4 RRBP1

1.34e-041919364303_DN
DrugDiphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A

ZNF512B SETD2 DIMT1 YLPM1 ZMYM2 CHD4

1.34e-041919366020_DN
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; PC3; HT_HG-U133A

SETD2 CDV3 HIPK1 ZMYM2 PHF14 CHD4

1.38e-041929364274_DN
DrugICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA

MBNL2 SYNJ2 LPP TMEM132A ZMYM2 PHF21A

1.38e-041929361076_UP
DrugCyanocobalamin [68-19-9]; Down 200; 3uM; MCF7; HT_HG-U133A

SETD2 VPS13D SYNJ2 HIPK1 DLG1 RRBP1

1.38e-041929363252_DN
DrugTropicamide [1508-75-4]; Down 200; 14uM; PC3; HT_HG-U133A

SETD1A SYNJ2 YLPM1 RBM42 ZMYM2 PTPRU

1.42e-041939364280_DN
Drugalpha-Santonin [481-06-1]; Down 200; 16.2uM; PC3; HT_HG-U133A

CDV3 MBNL2 SYNJ2 DAG1 ZMYM2 PHF14

1.46e-041949363795_DN
DrugGalanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A

SETD2 DIMT1 SGMS1 YLPM1 ZMYM2 PC

1.46e-041949364772_DN
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

CDV3 DIMT1 SFSWAP EGR3 BAZ1A CHD4

1.50e-041959361080_DN
Drugradicicol; Down 200; 0.1uM; MCF7; HG-U133A

SETD1A SASH1 RRBP1 KDM6B ADAMTSL4 ARHGEF15

1.50e-04195936489_DN
DrugSulfaphenazole [526-08-9]; Down 200; 12.8uM; HL60; HT_HG-U133A

DIMT1 PAPOLA YLPM1 ZMYM2 KDM6B PIGO

1.50e-041959361836_DN
DrugN-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A

SETD1A VPS13D DAG1 ZMYM2 PHF14 KDM6B

1.50e-041959363755_DN
Drugestradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A

SETD2 MBNL2 EGR3 LPP ANKMY1 ZYX

1.54e-041969361666_UP
DrugSimvastatin [79902-63-9]; Down 200; 9.6uM; HL60; HT_HG-U133A

SYNJ1 SYNJ2 LPP YLPM1 MAP3K14 PAK1

1.54e-041969363002_DN
Drugsodium 4-phenylbutyrate; Up 200; 100uM; HL60; HG-U133A

VPS13D LPP YLPM1 DAG1 PTPRU KDM6B

1.54e-04196936363_UP
DrugMuramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; HL60; HT_HG-U133A

SETD1A VPS13D CDV3 MAP3K14 RBM42 ZMYM2

1.54e-041969361326_UP
DrugMeclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; PC3; HT_HG-U133A

CDV3 MBNL2 SYNJ2 LPP CHD4 PIGO

1.59e-041979362128_DN
Drugrapamycin; Down 200; 0.1uM; MCF7; HG-U133A

VPS13D DIMT1 SPRR3 DLG1 RRBP1 MAN1B1

1.59e-04197936326_DN
Drugrosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A

MBNL2 SYNJ2 YLPM1 RRBP1 KDM6B ZYX

1.59e-041979361658_DN
DrugKetoconazole [65277-42-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A

VPS13D ZMYM2 PTPRU RRBP1 PC PIGO

1.59e-041979365685_DN
DrugTriamterene [396-01-0]; Down 200; 15.8uM; MCF7; HT_HG-U133A

ZNF512B SFSWAP YLPM1 RBM42 RRBP1 ZYX

1.59e-041979361697_DN
DrugBenfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; PC3; HT_HG-U133A

DIMT1 PAPOLA ZMYM2 ANKMY1 HSF1 PIGO

1.59e-041979366727_DN
DrugProtriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; HL60; HT_HG-U133A

ENOX1 SPRR3 LTBP1 POU6F1 RRBP1 ITPKA

1.59e-041979363119_UP
DrugPinacidil [85371-64-8]; Up 200; 16.4uM; PC3; HT_HG-U133A

MBNL2 SYNJ2 LPP TMEM132A PTPRU HSF1

1.63e-041989366356_UP
Drugmonastrol; Down 200; 100uM; PC3; HG-U133A

VPS13D HIPK1 MAP3K14 PC ZMYM4 ARHGEF15

1.68e-04199936668_DN
DrugAcenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A

SYNJ2 LPP TMEM132A ADGRB2 DAG1 ANKMY1

1.72e-042009362077_UP
DrugPergolide mesylate [66104-23-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A

SETD1A DIMT1 PAPOLA MBNL2 SYNJ2 RRBP1

1.72e-042009367031_UP
DrugNialamide [51-12-7]; Down 200; 13.4uM; PC3; HT_HG-U133A

ZMAT3 VPS13D CDV3 SYNJ2 TMEM132A PIGO

1.72e-042009364525_DN
DrugLidoflazine [3416-26-0]; Down 200; 8.2uM; MCF7; HT_HG-U133A

MGAT1 SASH1 KDM6B PC ZYX ZMYM4

1.72e-042009366278_DN
Diseaseearly-onset Parkinson's disease (implicated_via_orthology)

SYNJ1 SYNJ2

1.37e-046902DOID:0060894 (implicated_via_orthology)
DiseaseCongenital muscular dystrophy (disorder)

LAMA2 DAG1

1.37e-046902C0699743
DiseaseTourette syndrome

COL27A1 PTPRU CFAP99

4.85e-0450903EFO_0004895
Diseasebody mass index, osteoarthritis

RAPH1 PTPRM LTBP1

6.08e-0454903EFO_0004340, MONDO_0005178
DiseaseDown syndrome (implicated_via_orthology)

SYNJ1 SYNJ2

9.41e-0415902DOID:14250 (implicated_via_orthology)
DiseaseParkinson's disease (implicated_via_orthology)

SYNJ1 SYNJ2 HIPK1 HSF1

1.38e-03157904DOID:14330 (implicated_via_orthology)
Diseasemonocyte percentage of leukocytes

SETD2 LPP MAP3K14 ARHGAP30 KDM6B ZYX ZMYM4 EGFL6

1.78e-03731908EFO_0007989
Diseasemuscular dystrophy (implicated_via_orthology)

LAMA2 DAG1

1.86e-0321902DOID:9884 (implicated_via_orthology)
Diseaseplatelet reactivity measurement, response to clopidogrel

SYNJ1 MBNL2

2.23e-0323902EFO_0004985, GO_1903493
DiseaseIntellectual Disability

SETD1A SETD2 ZMYM2 KDM6B MAN1B1 PHF21A

2.49e-03447906C3714756
Diseasediet measurement, bilirubin measurement

SH3D19 LAMA2

2.85e-0326902EFO_0004570, EFO_0008111
Diseasemyeloperoxidase measurement

RRBP1 TNXB

2.85e-0326902EFO_0005243
DiseaseNeurodevelopmental Disorders

SETD2 PAK1 GIGYF2

2.92e-0393903C1535926

Protein segments in the cluster

PeptideGeneStartEntry
VRPPTQPPAEPLITV

ADGRB2

846

O60241
PEPTRTPTPKVNLQP

EGFL6

301

Q8IUX8
PEPPVPQLQPEILRV

ADAMTSL4

611

Q6UY14
LAVSPPQVPQPVPIR

CHD5

226

Q8TDI0
IVAPISDSPKPPPQR

PGLS

171

O95336
TTVASEPPVKLVPPP

BRD8

286

Q9H0E9
EPPVKLVPPPVESVS

BRD8

291

Q9H0E9
TVVPEKNPPPERQIP

BTK

66

Q06187
KPTEAVLPSPPTVPV

DLG1

161

Q12959
PTVPVIPVLPVPAEN

DLG1

171

Q12959
LPAATPPTQKPPRII

ARHGEF15

6

O94989
PVVDRTPLEPPPIVV

BMS1

71

Q14692
PVQAPPAPVIVTETP

CDV3

146

Q9UKY7
PEPTPVKTRLPPEIF

BAZ1A

411

Q9NRL2
VTPVQVPLLPVPSQP

RBM33

396

Q96EV2
IPTAVPAVPTVPTVP

RBM42

56

Q9BTD8
PPSPLSPVPSVVKQI

RAPH1

851

Q70E73
VVKQIASQFPPPPTP

RAPH1

861

Q70E73
RPRTIPAPEPVPVVA

CFAP99

196

D6REC4
VSRPLPSPKQEPPAV

GPR61

396

Q9BZJ8
KTPEPVVPTAPELQP

MDC1

1156

Q14676
VPTAAPPAQPRVPVT

MGAT1

86

P26572
QPIIIPDTPSPPVSV

HIPK1

891

Q86Z02
APEFPIPPIKIQRVP

KIAA2026

491

Q5HYC2
INTTAKVPVPPPVPT

KIAA2026

1986

Q5HYC2
PDVVPVPETPTRAPQ

KSR2

576

Q6VAB6
PVKRAAEPPVVQPVP

KDM6B

196

O15054
EPISPVPPSVEEIPV

DCLK2

716

Q8N568
PPTTAIQEPPSRIVP

DAG1

326

Q14118
PPVRDPVPGKPTVTI

DAG1

356

Q14118
RVKEEPPSPPQSPRV

HSF1

296

Q00613
PQFPVVIEKTSPPVP

LTBP1

836

Q14766
AGPIPIRPPIVPVKT

MTSS2

581

Q765P7
IRPPIVPVKTPTVPD

MTSS2

586

Q765P7
QPIKVPQFIPPPRLT

PHF21A

211

Q96BD5
PIQPTPTVPQPAVVI

POU6F1

86

Q14863
TIDLKRNETPPVPPP

KIAA0408

256

Q6ZU52
IPVAPIGTLKPQPQP

LPP

191

Q93052
IKEPAPLPSRPQVPT

MNT

131

Q99583
EIVIQPEPVPTPAFP

LAMA2

2726

P24043
SVPKQIPPRPPEGLT

LRRC63

266

Q05C16
VPQDVPPEPKKIPIR

PHF14

811

O94880
PERSVPKEAEPTPPV

CRACDL

431

Q6NV74
AEVPTKPPLPPARTQ

MAN1B1

226

Q9UKM7
LPAIPVPIKPTPAAV

FOXB1

256

Q99853
PRAPPAPVIPQLTVT

ITPKA

71

P23677
IVKEPPTPIAPPQLL

PTPRU

281

Q92729
SPPEPPSPQEILIKV

FAM171A2

31

A8MVW0
QPAISPPPKPTVSRV

PAPOLA

601

P51003
PPPVIAPRPEHTKSV

PAK1

186

Q13153
SPPPTPVQRRLEVPV

CEFIP

116

Q711Q0
PVRNPKIVVPIPVHV

GBX1

331

Q14549
QPVTIKPPPPEVVSR

CASC3

686

O15234
PIKPFPSRPPVLTQE

CC2D2A

356

Q9P2K1
PNPSPTLRPVETPVV

GIGYF2

456

Q6Y7W6
DPIRVNPPPITPLET

EGR3

216

Q06889
TIPEPQEPPKFPVVP

ANKMY1

351

Q9P2S6
LPTQKQVPPTSRPVP

COL27A1

401

Q8IZC6
TTPVIVPGSPPVTVP

MBNL2

151

Q5VZF2
KVRPPTVPVPQVDIV

C2orf81

21

A6NN90
VTATEVAPPPPPVEV

CHD4

241

Q14839
VVPPPTIPPVVPTSL

SCAF8

701

Q9UPN6
PPPPPTEVAVVKEII

ENOX1

101

Q8TC92
DPQRPPRPEVKITSP

DCDC2

446

Q9UHG0
EAPQVPRIPPPVHKT

CNTROB

746

Q8N137
VVRIEPKNPPPPINF

DIMT1

206

Q9UNQ2
VIRVPSVPPVPCVPS

KRT36

416

O76013
LVVKEPPVPIAPPQL

PTPRM

276

P28827
VQQVRSVPVVPPKPQ

ARHGAP30

931

Q7Z6I6
LKIASEPPPVREIPP

MAP3K14

606

Q99558
PEPEPIVLPSVVPLV

FAM83G

321

A6ND36
LPPVPKPRTVPVADV

FAM83G

501

A6ND36
NPLQPVPVVKPAVLP

TAF4

786

O00268
PKPTVPIRIIIVGPP

AK9

1406

Q5TCS8
VAAIIPPPPDVQPVI

SFSWAP

446

Q12872
KTIPTQQPPTKVPPE

SH3D19

331

Q5HYK7
VVPPRVTEPHQRPVP

TMEM132A

106

Q24JP5
PVPTPDPKRLIQLPS

SYNJ1

1346

O43426
SVEAPPVVTAPRVPP

SYNJ2

1271

O15056
PPPSSSVRVRPVVPE

NHSL2

736

Q5HYW2
VPTPAPVEVPVPERV

SETD1A

1086

O15047
VAVEPEVPPVPLPTA

SHANK1

1816

Q9Y566
QPPPQEIFVPTTKEP

SPRR3

26

Q9UBC9
PPVLPIRSEKEPLPV

CHRD

31

Q9H2X0
VKAPPTQPVLPPQTI

YTHDF3

286

Q7Z739
AVAPTPVQPPIIVAP

RRBP1

106

Q9P2E9
PVQPPIIVAPVATVP

RRBP1

111

Q9P2E9
GAKPEVPRIVVQPPE

TBC1D10C

386

Q8IV04
QAVPTMTPEPPIKPR

TNXB

2616

P22105
EVTEPPPQIVPEVPQ

SASH1

856

O94885
VHERVPPKEVQPPLP

SGMS1

156

Q86VZ5
PPVPVVPHVAAPVEV

SETD2

2221

Q9BYW2
QVPEKPRPALLPTPV

YLPM1

661

P49750
VQPPPPSVPVVADQR

ZMYM2

66

Q9UBW7
SQNIPVPTTVPVPVP

ZMYM2

901

Q9UBW7
VPTTVPVPVPVPVFL

ZMYM2

906

Q9UBW7
PMPVTKAIPVTRPVP

ZNF512B

221

Q96KM6
IPPPPQPREKVSSID

ZYX

131

Q15942
VVEPAATPVVPVPPQ

ZMAT3

116

Q9HA38
PPEEPEVIPQVSLVP

PIGO

311

Q8TEQ8
IPVKASPSPTDPVVP

PC

516

P11498
PSVVTVPEPPVVAEP

SON

1386

P18583
VVPVPVPVFVPIPLH

ZMYM4

981

Q5VZL5
TPPPSPTVDEPKILV

VPS13D

1761

Q5THJ4
PPAPKVEITPEPVSV

MYPOP

326

Q86VE0