Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of skeletal muscle fiber differentiation

HDAC9 HDAC5 NLN

5.23e-0671113GO:1902809
GeneOntologyCellularComponenthost cell part

GBP6 GBP4

4.21e-0461122GO:0033643
GeneOntologyCellularComponenthost intracellular part

GBP6 GBP4

4.21e-0461122GO:0033646
GeneOntologyCellularComponenthost cell cytoplasm part

GBP6 GBP4

4.21e-0461122GO:0033655
GeneOntologyCellularComponentsymbiont-containing vacuole

GBP6 GBP4

4.21e-0461122GO:0020003
GeneOntologyCellularComponentsymbiont-containing vacuole membrane

GBP6 GBP4

4.21e-0461122GO:0020005
GeneOntologyCellularComponenthost intracellular region

GBP6 GBP4

4.21e-0461122GO:0043656
GeneOntologyCellularComponenthost cell cytoplasm

GBP6 GBP4

4.21e-0461122GO:0030430
DomainHDAC4_Gln

HDAC9 HDAC5

1.01e-0431092PF12203
DomainHist_deacetylase_Gln_rich_N

HDAC9 HDAC5

1.01e-0431092IPR024643
DomainHistone_deAcase_II_euk

HDAC9 HDAC5

2.01e-0441092IPR017320
DomainGrowth_fac_rcpt_

FAT4 INSR LAMA3 LAMB1 SCUBE1 SCUBE2

3.08e-041561096IPR009030
DomainKinase-like_dom

CDKL2 HIPK1 INSR DYRK1A ACVR1B PXK PIK3R4 JAK2 BMX PIK3C2G DSTYK

3.27e-0454210911IPR011009
DomainLipase_GDSL

PLB1 PAFAH1B2

3.34e-0451092PF00657
DomainGDSL

PLB1 PAFAH1B2

3.34e-0451092IPR001087
DomainCPSASE_1

CAD ACACB

3.34e-0451092PS00866
DomainLIPASE_GDSL_SER

PLB1 PAFAH1B2

3.34e-0451092PS01098
DomainXpo1

XPO1 XPO5

4.99e-0461092PF08389
DomainCPSASE_2

CAD ACACB

4.99e-0461092PS00867
DomainExportin-1/Importin-b-like

XPO1 XPO5

4.99e-0461092IPR013598
DomainProt_kinase_dom

CDKL2 HIPK1 INSR DYRK1A ACVR1B PXK PIK3R4 JAK2 BMX DSTYK

5.82e-0448910910IPR000719
DomainPROTEIN_KINASE_DOM

CDKL2 HIPK1 INSR DYRK1A ACVR1B PXK PIK3R4 JAK2 BMX DSTYK

6.19e-0449310910PS50011
DomainEGF-like_dom

FAT4 LAMA3 LAMB1 ADAM12 SCUBE1 SCUBE2 MUC4

6.46e-042491097IPR000742
DomainCbamoylP_synth_lsu-like_ATP-bd

CAD ACACB

6.95e-0471092IPR005479
DomainBC-like_N

CAD ACACB

6.95e-0471092IPR005481
DomainCPSase_L_D2

CAD ACACB

6.95e-0471092PF02786
DomainBiotin_carb_N

CAD ACACB

6.95e-0471092PF00289
Domain-

PLB1 PAFAH1B2

6.95e-04710923.40.50.1110
DomainEGF_1

FAT4 LAMA3 LAMB1 ADAM12 SCUBE1 SCUBE2 MUC4

7.44e-042551097PS00022
DomainHEAT_REPEAT

COPG1 XPO1 NCAPG2 PIK3R4

7.48e-04701094PS50077
DomainARM-type_fold

COPG1 APOB XPO1 NCAPG2 PIK3R4 XPO5 PIK3C2G RRP12

8.41e-043391098IPR016024
DomainEGF-like_CS

FAT4 LAMA3 LAMB1 ADAM12 SCUBE1 SCUBE2 MUC4

8.52e-042611097IPR013032
DomainSGNH_hydro

PLB1 PAFAH1B2

9.24e-0481092IPR013830
DomainEGF_2

FAT4 LAMA3 LAMB1 ADAM12 SCUBE1 SCUBE2 MUC4

9.31e-042651097PS01186
Domain-

ADAMTS4 ADAM12 NLN MMP17

1.29e-038110943.40.390.10
DomainMetalloPept_cat_dom

ADAMTS4 ADAM12 NLN MMP17

1.29e-03811094IPR024079
DomainPROTEIN_KINASE_ATP

CDKL2 HIPK1 INSR DYRK1A ACVR1B PIK3R4 JAK2 BMX DSTYK

1.47e-034591099PS00107
DomainGBP_C

GBP6 GBP4

1.47e-03101092PF02841
DomainProtein_kinase_ATP_BS

CDKL2 HIPK1 INSR DYRK1A ACVR1B JAK2 BMX DSTYK

1.71e-033791098IPR017441
DomainHist_deacetyl

HDAC9 HDAC5

1.79e-03111092PF00850
DomainEphrin_rec_like

SCUBE1 SCUBE2

1.79e-03111092PF07699
DomainG_GB1_RHD3_dom

GBP6 GBP4

1.79e-03111092IPR030386
Domain-

HDAC9 HDAC5

1.79e-031110923.40.800.20
DomainGuanylate-bd_N

GBP6 GBP4

1.79e-03111092IPR015894
DomainGuanylate-bd_C

GBP6 GBP4

1.79e-03111092IPR003191
DomainHis_deacetylse_dom

HDAC9 HDAC5

1.79e-03111092IPR023801
DomainGBP

GBP6 GBP4

1.79e-03111092PF02263
DomainHis_deacetylse

HDAC9 HDAC5

1.79e-03111092IPR000286
DomainG_GB1_RHD3

GBP6 GBP4

1.79e-03111092PS51715
Domain-

COPG1 XPO1 NCAPG2 PIK3R4 XPO5 RRP12

1.93e-0322210961.25.10.10
DomainEGF_dom

SCUBE1 SCUBE2

2.14e-03121092IPR024731
DomainEGF_3

SCUBE1 SCUBE2

2.14e-03121092PF12947
Domainzf-C2H2_6

ZNF845 ZNF195 ZNF71 ZNF526 ZNF587 ZNF417 ZNF121

2.45e-033141097PF13912
Domain-

CAD ACACB

2.52e-031310923.40.50.20
DomainEGF

FAT4 LAMA3 LAMB1 SCUBE1 SCUBE2 MUC4

2.57e-032351096SM00181
DomainZINC_PROTEASE

ADAMTS4 ADAM12 NLN MMP17

2.60e-03981094PS00142
DomainATP_GRASP

CAD ACACB

2.93e-03141092PS50975
DomainATP-grasp

CAD ACACB

2.93e-03141092IPR011761
DomainPreATP-grasp_dom

CAD ACACB

2.93e-03141092IPR016185
Domain-

CAD ACACB

3.37e-031510923.30.1490.20
DomainLaminin_N

LAMA3 LAMB1

3.84e-03161092IPR008211
DomainIBN_N

XPO1 XPO5

3.84e-03161092SM00913
DomainLamNT

LAMA3 LAMB1

3.84e-03161092SM00136
DomainLAMININ_NTER

LAMA3 LAMB1

3.84e-03161092PS51117
DomainLaminin_N

LAMA3 LAMB1

3.84e-03161092PF00055
DomainImportin-beta_N

XPO1 XPO5

4.33e-03171092IPR001494
DomainHEAT

XPO1 NCAPG2 PIK3R4

4.73e-03581093IPR000357
DomainATP_grasp_subdomain_1

CAD ACACB

4.86e-03181092IPR013815
Domain-

CAD ACACB

4.86e-031810923.30.470.20
DomainARM-like

COPG1 XPO1 NCAPG2 PIK3R4 XPO5 RRP12

5.06e-032701096IPR011989
Pubmed

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.

CAD COPG1 APOB XPO1 STT3A XPO5

1.96e-06113113630352685
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

KIF13B TTC28 MYCBP2 KIF26B DYRK1A ALS2 INPP5F PIK3R4 STOX2 BMX AASS DSTYK USP54

4.72e-068611131336931259
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

GATD3 COPG1 ACAT2 HSPH1 XPO1 TIPRL NT5DC1 STT3A PRUNE1 XPO5 NCEH1 ALDH1B1 ZNF292

5.82e-068781131337223481
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

COPG1 HSPH1 XPO1 XPO5 AASS ALDH1B1 ZNF121

6.14e-06211113717314511
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RHBDF2 MYCBP2 JADE2 INSR LAMA3 GRIK2 POMT1 STT3A JAK2 ZNF587 KLHL23 CDYL2 SPIDR TATDN1 TET3 EP300 ADGRD1

6.43e-0614891131728611215
Pubmed

Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved.

HSPH1 XPO1 STT3A CYFIP1 TUBA4B ALDH1B1 ATP2A1

7.37e-06217113730619736
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

APPBP2 HDAC5 TTC28 HIPK1 ALS2 KLHL32 XPO5 RRP12 TET3

7.70e-06407113912693553
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

HDAC5 TTC28 MYCBP2 ALS2 NLN XPO5 HELZ2

9.33e-06225113712168954
Pubmed

Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli.

HDAC9 HDAC5

1.05e-052113217988634
Pubmed

Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin.

HDAC9 HDAC5 EP300

1.18e-0514113315601857
Pubmed

The human plasma proteome: a nonredundant list developed by combination of four separate sources.

CP APOB DBH AGL PAFAH1B2 KLKB1

1.73e-05165113614718574
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

CAD COPG1 HSPH1 XPO1 RUFY1 CYFIP1 XPO5 ATP2A1

1.75e-05344113836282215
Pubmed

ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.

ADAMTS4 LAMA3 LAMB1

1.81e-0516113330579834
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAT4 APPBP2 COPG1 CDKL2 KIF26B HSPH1 BMS1 ACVR1B JAK2 AGL TUBE1

2.91e-057361131129676528
Pubmed

Identification of a novel family of cell-surface proteins expressed in human vascular endothelium.

SCUBE1 SCUBE2

3.13e-053113212270931
Pubmed

Mutations in the liver glycogen synthase gene in children with hypoglycemia due to glycogen storage disease type 0.

AGL GYS2

3.13e-05311329691087
Pubmed

Downregulation of a newly identified laminin, laminin-3B11, in vascular basement membranes of invasive human breast cancers.

LAMA3 LAMB1

3.13e-053113221276136
Pubmed

Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage.

INSR GLP1R

3.13e-053113216322793
Pubmed

Prognostic Impact of FSTL3, ADAM12, and FAT4 in Patients of Colon Cancer: Clinicopathologic Study.

FAT4 ADAM12

3.13e-053113237751246
Pubmed

The relationship of serum SCUBE-1, -2 and -3 levels with clinical findings and ultrasonographic skin thickness in systemic sclerosis patients.

SCUBE1 SCUBE2

3.13e-053113231991528
Pubmed

Postnatal DNA demethylation and its role in tissue maturation.

INSR TET3

3.13e-053113229795194
Pubmed

Acetylation of sox2 induces its nuclear export in embryonic stem cells.

XPO1 EP300

3.13e-053113219591226
Pubmed

Prediction of the metabolic syndrome status based on dietary and genetic parameters, using Random Forest.

ACACB APOB

3.13e-053113219034549
Pubmed

Overexpression of ALK4 inhibits cell proliferation and migration through the inactivation of JAK/STAT3 signaling pathway in glioma.

ACVR1B JAK2

3.13e-053113229278854
Pubmed

Dephosphorylation at a conserved SP motif governs cAMP sensitivity and nuclear localization of class IIa histone deacetylases.

HDAC9 HDAC5

3.13e-053113223297420
Pubmed

SHPTP2 serves adapter protein linking between Janus kinase 2 and insulin receptor substrates.

INSR JAK2

3.13e-05311328912646
Pubmed

Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking.

RUFY1 BMX

3.13e-053113211877430
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

HDAC9 KIF13B ADAMTS4 HSPH1 ZNF526 DSTYK HELZ2 NCEH1 SPIDR

3.48e-05493113915368895
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ACACB HSPH1 XPO1 RUFY1 PIK3R4 CYFIP1 RRP12 MUC4 ZNF292

3.71e-05497113936774506
Pubmed

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

ACACB INSR APOB DBH PIK3C2G GYS2

4.05e-05192113620602615
Pubmed

Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.

ACACB ACAT2 INSR PIK3C2G GYS2

4.15e-05117113518996102
Pubmed

Analysis of BCL6-interacting proteins by tandem mass spectrometry.

HDAC9 KIF13B HDAC5 HELZ2

5.10e-0562113416147992
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

CAD MYCBP2 AGL RRP12 USP54 ATP2A1

5.37e-05202113624639526
Pubmed

ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques.

ADAMTS4 APOB

6.25e-054113217606262
Pubmed

Structural requirement of carboxyl-terminal globular domains of laminin alpha 3 chain for promotion of rapid cell adhesion and migration by laminin-5.

LAMA3 LAMB1

6.25e-054113210801807
Pubmed

ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1.

ADAMTS4 MMP17

6.25e-054113214701864
Pubmed

Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5.

HDAC9 HDAC5

6.25e-054113210655483
Pubmed

mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity.

HDAC9 HDAC5

6.25e-054113210748098
Pubmed

FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.

FAT4 STT3A

6.25e-054113237658376
Pubmed

Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling.

INSR PIK3R4

6.25e-054113226387534
Pubmed

LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and α-synuclein-induced degeneration in cellular models of Parkinson's disease.

HDAC9 HDAC5

6.25e-054113234119632
Pubmed

Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.

HIPK1 DYRK1A

6.25e-054113234785661
Pubmed

Histone deacetylase 9 is a negative regulator of adipogenic differentiation.

HDAC9 EP300

6.25e-054113221680747
Pubmed

Class IIa histone deacetylases: conducting development and differentiation.

HDAC9 HDAC5

6.25e-054113219412888
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

HDAC9 GATD3 TTC28 MYCBP2 JADE2 HIPK1 HSPH1 DYRK1A LAMB1 DNAAF9 PIK3R4 USP54 EP300 ZNF292

7.47e-0512851131435914814
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

COPG1 BMS1 LAMB1 XPO1 TIPRL NCAPG2 STT3A PRUNE1 CYFIP1 XPO5 AGL ATP2A1

8.05e-059741131228675297
Pubmed

Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1.

HDAC9 HDAC5

1.04e-045113215194749
Pubmed

Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases.

HDAC9 HDAC5

1.04e-045113220188095
Pubmed

Transcriptional activation of hypoxia-inducible factor-1alpha by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1.

HDAC5 EP300

1.04e-045113219071119
Pubmed

Kinase activation through dimerization by human SH2-B.

INSR JAK2

1.04e-045113215767667
Pubmed

Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4.

HDAC9 HDAC5

1.04e-045113218332106
Pubmed

Mirk/dyrk1B decreases the nuclear accumulation of class II histone deacetylases during skeletal muscle differentiation.

HDAC9 HDAC5

1.04e-045113215546868
Pubmed

Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse.

SCUBE1 SCUBE2

1.04e-045113223383134
Pubmed

RANKL induces NFATc1 acetylation and stability via histone acetyltransferases during osteoclast differentiation.

HDAC5 EP300

1.04e-045113221413932
Pubmed

The metastasis-promoting phosphatase PRL-3 shows activity toward phosphoinositides.

INSR JAK2

1.04e-045113221806020
Pubmed

Dual mechanism of signal transducer and activator of transcription 5 activation by the insulin receptor.

INSR JAK2

1.04e-045113212456798
Pubmed

Myocyte enhancer factor 2 and class II histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor.

HDAC9 HDAC5

1.04e-045113219893013
Pubmed

Interaction of Janus kinases JAK-1 and JAK-2 with the insulin receptor and the insulin-like growth factor-1 receptor.

INSR JAK2

1.04e-04511329492017
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ADAMTS4 HIPK1 INSR ACVR1B INPP5F ADAM12 STT3A MMP17 TUBE1 EP300

1.39e-047301131034857952
Pubmed

Genetic associations of brain structural networks in schizophrenia: a preliminary study.

APOB DBH GYS2

1.40e-0431113320691427
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

FAT4 MYCBP2 HSPH1 LAMB1 GRIK2 POMT1 ADAM12 RUFY1 NCAPG2 NT5DC1 STT3A RRP12 NCEH1

1.46e-0412011131335696571
Pubmed

Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4.

HDAC9 EP300

1.56e-046113210825153
Pubmed

Genetic mapping of mouse tumor necrosis factor-alpha converting enzyme (TACE) to chromosome 12.

LAMB1 APOB

1.56e-04611329598327
Pubmed

Suppressor of cytokine signaling-3 Provides a novel interface in the cross-talk between angiotensin II and insulin signaling systems.

INSR JAK2

1.56e-046113215514089
Pubmed

DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers.

DYRK1A EP300

1.56e-046113230137413
Pubmed

Class II histone deacetylases confer signal responsiveness to the ankyrin-repeat proteins ANKRA2 and RFXANK.

HDAC5 XPO1

1.56e-046113216236793
Pubmed

Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma.

HDAC5 EP300

1.56e-046113224229708
Pubmed

p300-mediated acetylation stabilizes the Th-inducing POK factor.

HSPH1 EP300

1.56e-046113220810990
Pubmed

Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation.

HDAC9 HDAC5

1.56e-046113216356933
Pubmed

Expression and localization of laminin-5 subunits in the mouse incisor.

LAMA3 LAMB1

1.56e-04611329506922
Pubmed

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells.

HDAC9 HDAC5

1.56e-046113219351956
Pubmed

Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation.

HIPK1 EP300

1.56e-046113216917507
Pubmed

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1.

INSR JAK2

1.56e-046113210635327
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

RHBDF2 HSPH1 APOB POMT1 ACVR1B ZDHHC3 NCAPG2 STT3A JAK2 NLN XPO5 NCEH1

1.79e-0410611131233845483
Pubmed

Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells.

CAD COPG1 GLP1R NCEH1

1.83e-0486113425044020
Pubmed

Inceptor counteracts insulin signalling in β-cells to control glycaemia.

ACACB INSR GLP1R

1.86e-0434113333505018
Pubmed

Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor.

LAMA3 LAMB1

2.17e-04711329004048
Pubmed

Disruption of Scube2 Impairs Endochondral Bone Formation.

SCUBE1 SCUBE2

2.17e-047113225639508
Pubmed

A new nomenclature for the laminins.

LAMA3 LAMB1

2.17e-04711327921537
Pubmed

Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion.

HDAC5 EP300

2.17e-047113217872950
Pubmed

Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor.

HDAC9 HDAC5

2.17e-047113211022042
Pubmed

Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes.

HDAC5 EP300

2.17e-047113217075044
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

GATD3 CAD COPG1 JADE2 HSPH1 BMS1 LAMB1 XPO1 NCAPG2 STT3A XPO5 AASS RRP12 ALDH1B1

2.44e-0414401131430833792
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

EXOC6 FAT4 PDE6A ACACB TTC28 TBC1D25 CYFIP1 AASS EP300

2.44e-04638113931182584
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SDSL RHBDF2 MYCBP2 DYRK1A TBC1D25 SFI1 JAK2 RRP12 HELZ2 HES6 MMP17 EP300

2.59e-0411051131235748872
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

COPG1 ACAT2 HSPH1 LAMB1 DYNLT3 XPO1 RUFY1 CYFIP1 XPO5 AGL PAFAH1B2 TUBA4B ALDH1B1 TATDN1

2.71e-0414551131422863883
Pubmed

A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles.

PXK JAK2 SCUBE1

2.80e-0439113320962850
Pubmed

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1.

HDAC5 EP300

2.89e-048113224413532
Pubmed

Expression and localization of laminin-5 subunits during mouse tooth development.

LAMA3 LAMB1

2.89e-04811329489770
Pubmed

Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation.

HDAC9 HDAC5

2.89e-048113212242305
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMA3 LAMB1

2.89e-04811328872465
Pubmed

Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis.

LAMA3 LAMB1

2.89e-048113223529140
Pubmed

Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.

HDAC9 HDAC5

2.89e-048113217786239
Pubmed

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.

GBP6 GBP4

2.89e-048113216689661
Pubmed

Glucagon regulates hepatic kisspeptin to impair insulin secretion.

INSR GLP1R

2.89e-048113224703698
Pubmed

TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.

KIF13B CAD HSPH1 XPO1 AGL

3.06e-04179113536261009
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

CAD COPG1 MYCBP2 HSPH1 BMS1 LAMB1 APOB XPO1 TIPRL STT3A CYFIP1 XPO5 NCEH1

3.08e-0412971131333545068
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF845 ZNF195 ZNF587 ZNF417 ZNF121

3.22e-04181113537372979
Pubmed

Association study of 182 candidate genes in anorexia nervosa.

ACACB COPG1 INSR DBH GLP1R

3.30e-04182113520468064
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

KIF13B ADAMTS4 HIPK1 RRP12

3.51e-0410211349734811
GeneFamilyHistone deacetylases, class IIA

HDAC9 HDAC5

9.08e-054712992
GeneFamilyExportins

XPO1 XPO5

3.15e-047712547
GeneFamilyLaminin subunits

LAMA3 LAMB1

9.78e-0412712626
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

FMO2 INSR CP GRIK2 SCUBE2 MUC4 SEMA3E

5.68e-071901137756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

FMO2 CP GRIK2 SCUBE2 USP54 MUC4 SEMA3E

6.31e-0719311372bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KIF13B ADAMTS4 INPP5F KLHL32 ADCY5 PXK USP54

7.24e-07197113782b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FMO2 INSR CP GRIK2 SCUBE2 MUC4 SEMA3E

7.49e-071981137af399569c718f5fd971d73a7926768c9311002a3
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMB1 ADAM12 ADCY5 CDYL2 MMP17 ADGRD1

3.05e-061571136bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A PLB1 KCTD19 GRIK2 PIK3C2G AASS

3.40e-061601136c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A PLB1 KCTD19 GRIK2 PIK3C2G AASS

3.40e-06160113625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACB ACAT2 CP APOB HES6 KLKB1

4.06e-061651136d449a568664a81d9b5538e8f409301448a32ac37
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A FAT4 GRIK2 ADAM12 MMP17 SEMA3E

4.66e-06169113687116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACB CP ADCY5 BMX TRIM38 ADGRD1

5.69e-061751136f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCellAdult-Epithelial-club_cell-D175|Adult / Lineage, Cell type, age group and donor

FMO2 INSR CP SCUBE2 AASS MUC4

6.07e-061771136d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

FMO2 INSR CP GRIK2 MUC4 SEMA3E

6.27e-06178113635a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 ADAMTS4 LAMB1 APOB ADCY5 SCUBE1

6.90e-061811136b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FMO2 ACACB TTC28 LAMA3 ZNF526 BMX

6.90e-061811136136b0c60680068838d184d32aa99d7bea8718dbc
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

FMO2 INSR CP GRIK2 MUC4 SEMA3E

8.31e-061871136ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FMO2 CP GRIK2 SCUBE2 MUC4 SEMA3E

9.38e-06191113623776c7302cead3881b39127398f3b3e0d27885e
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-6|TCGA-Stomach / Sample_Type by Project: Shred V9

LAMA3 STT3A JAK2 CYFIP1 GBP4 NCEH1

9.66e-0619211364e689bca7a242f8482e25f273656e2caba8821c0
ToppCellnucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FMO2 INSR CP GRIK2 USP54 MUC4

1.02e-0519411360cd4363627acd419e00d6d32f6dce10430aa6487
ToppCellnucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FMO2 INSR CP GRIK2 USP54 MUC4

1.02e-051941136a58841b34efe673671a9a059238e044a7254b279
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FMO2 CP GRIK2 SCUBE2 USP54 SEMA3E

1.15e-0519811365fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FMO2 CP GRIK2 SCUBE2 MUC4 SEMA3E

1.15e-0519811361408e02e053ad3406229bfe8189da03be6366e81
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FMO2 CP GRIK2 SCUBE2 USP54 SEMA3E

1.15e-0519811366ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCellSigmoid-T_cell-Tfh|Sigmoid / Region, Cell class and subclass

PLB1 DYRK1A SFI1 KLHL32 HELZ2 ZNF121

1.18e-051991136fa9404a021a015d1d571c324780b6eef2da47c4c
ToppCellSigmoid-(1)_T_cell-(16)_Tfh|Sigmoid / shred on region, Cell_type, and subtype

PLB1 DYRK1A SFI1 KLHL32 HELZ2 ZNF121

1.18e-051991136a61bf52d2d359746433623ee00337124f1f84f61
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FMO2 INSR CP PIK3C2G MUC4 SEMA3E

1.22e-052001136b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 DBH ADCY5 KLHL23 SLC38A11 ADGRD1

1.22e-052001136600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Striatum / BrainAtlas - Mouse McCarroll V32

FMO2 RHBDF2 BMX GBP4 HELZ2

2.62e-051371135306b11b3b9e5fd562d845fb5eaa4ac982864efce
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK|Striatum / BrainAtlas - Mouse McCarroll V32

FMO2 RHBDF2 BMX GBP4 HELZ2

2.62e-051371135d37f425b13bc046baa1f8619b98a16b936f88ff6
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK|Hippocampus / BrainAtlas - Mouse McCarroll V32

FMO2 RHBDF2 BMX GBP4 HELZ2

2.81e-05139113534398a6f21a1e670497655a7bb7f3cde9e117560
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

FMO2 RHBDF2 BMX GBP4 HELZ2

2.81e-051391135450c4152c9fe4ec503271bb3cf93739918c59509
ToppCell(02)_Cycling_Basal_(regeneration)-(2)_48hpi|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint

CP XPO1 PXK HES6 MUC4

3.80e-051481135a061a745c09254e063411b7d835d5597a0007e29
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PDE6A ZNF526 CYFIP1 GBP4 TRIM38

4.05e-0515011356c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_large-bowel / Manually curated celltypes from each tissue

HDAC5 HSPH1 LAMB1 SCUBE1 TUBA4B

4.31e-05152113595944864ce7539ff8de028f5700694931338f3ff
ToppCellClub_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

FMO2 CP SCUBE2 MUC4 SEMA3E

5.50e-051601135b261a3a49c850d92bc9e04fc3527c752dfe37a1a
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

INPP5F GBP4 HES6 ATP2A1 TET3

6.01e-0516311359f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 ZDHHC3 PXK PIK3C2G SLC38A11

6.37e-0516511359bd332e5ede759a00a47728ea5558c215efdd77a
ToppCellIonocyte|World / shred by cell class for turbinate

KIF26B SCUBE2 GYS2 KLHL23 HES6

6.37e-0516511350cb2199b87f17ece743fb2652b2f448dfa78ae0b
ToppCellBL-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FAT4 ADCY5 SCUBE2 KLHL23 MMP17

7.33e-051701135b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAM12 ADCY5 CDYL2 MMP17 ADGRD1

7.33e-0517011355570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellBronchial_Biopsy-Epithelial-Ionocytes|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

APOB ADCY5 SCUBE2 KLHL23 HES6

8.18e-0517411357e7b13de916cd4fa0fa6fb06e6b4942877afa9fb
ToppCellBasal_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FMO2 CP DSTYK ZNF417 MMP17

8.18e-051741135a0060be3940043015dcc49a5157de5541aed24a1
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|356C / Donor, Lineage, Cell class and subclass (all cells)

FMO2 INSR CP MUC4 SEMA3E

8.40e-051751135af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCellBronchial_Biopsy-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

APOB ADCY5 SCUBE2 KLHL23 HES6

8.40e-05175113513b8f7dc38c90b74d4a20a84a8705d8e2ec244f6
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|356C / Donor, Lineage, Cell class and subclass (all cells)

FMO2 INSR CP MUC4 SEMA3E

8.40e-0517511354bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_1-Pericyte|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS4 KLHL23 CDYL2 SLC38A11 ADGRD1

8.87e-05177113568263456a3c93cd195b321b309ff59e156d732fe
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_1|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS4 KLHL23 CDYL2 SLC38A11 ADGRD1

8.87e-051771135e415e448c37adc102d766235e9953dec32c021f1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC3 PXK PIK3C2G SLC38A11 ZNF417

8.87e-051771135f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CP GRIK2 SCUBE2 MUC4 SEMA3E

9.60e-051801135b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMB1 ADCY5 KLHL23 SLC38A11 ADGRD1

9.85e-051811135451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FMO2 CP USP54 MUC4 SEMA3E

1.01e-041821135215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMB1 ADCY5 CDYL2 MMP17 ADGRD1

1.04e-0418311358a799807fbf24456a9811e0c64068187940a2f71
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 KIF26B APOB SFI1 PIK3C2G

1.06e-0418411352cbed6462fea2622871bb7e49b0df3d984239281
ToppCellIPF-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

ALS2 ADAM12 AASS SLC38A11 IL9R

1.06e-0418411357326a16d7d3ae41b8c9d2beaec7f977b374f3469
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 KIF26B APOB SFI1 PIK3C2G

1.06e-041841135ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 KIF26B APOB SFI1 PIK3C2G

1.06e-0418411352b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

VWA3A FMO2 CP TUBA4B MUC4

1.06e-04184113507c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS4 LAMB1 ADAM12 ADCY5 CDYL2

1.06e-041841135327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD42 LAMB1 ADCY5 SCUBE1 MMP17

1.09e-041851135f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

MYCBP2 SFI1 XPO1 ZNF587 ZNF292

1.09e-041851135a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

HDAC9 FMO2 INSR CP MUC4

1.09e-0418511356814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

ADAMTS4 LAMB1 ADCY5 KLHL23 ADGRD1

1.09e-0418511354905adaeeffd353e089578e5ea614437dbe794e6
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD42 LAMB1 ADCY5 SCUBE1 MMP17

1.09e-04185113540e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD42 LAMB1 ADCY5 SCUBE1 MMP17

1.09e-0418511355f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VWA3A NT5DC1 STOX2 ADGRD1 SEMA3E

1.09e-0418511359f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellCOPD-Stromal-Pericyte|World / Disease state, Lineage and Cell class

ADAMTS4 LAMB1 AASS KLHL23 ADGRD1

1.12e-0418611358adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

MYCBP2 SFI1 XPO1 ZNF587 ZNF292

1.12e-0418611358571956890fc9894d766ba294a28e376b4aba428
ToppCellPCW_05-06-Neuronal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIF13B GRIK2 DBH ADAM12 MMP17

1.15e-04187113503a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIF13B DYRK1A INPP5F ZNF417 IL9R

1.15e-041871135c667fae6440dc98072b584f203d00f0fb1cb2f21
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|368C / Donor, Lineage, Cell class and subclass (all cells)

KIF13B DYRK1A INPP5F ZNF417 IL9R

1.18e-041881135ecc2364d946f97ae0212fd6739960c9fc75e4919
ToppCellAT1-AT2_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

FMO2 LAMA3 SCUBE1 USP54 SEMA3E

1.18e-041881135be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPH1 ALS2 ADAM12 SLC38A11 IL9R

1.21e-041891135f01158bb15df3117fae1271bf8cf8c2501422671
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS4 LAMB1 ADCY5 KLHL23 ADGRD1

1.24e-0419011354eb92aef1ee868f4537483d19014d947b7684612
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

EXOC6 FAT4 TTC28 HSPH1 BMX

1.24e-04190113507b675befcd1d0a9c90cb17b5d22323468325d51
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF26B LAMB1 ADAM12 SPIDR ADGRD1

1.24e-04190113545df8fee00f8949937863159d7aa042e72748d9b
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TTC28 ADAMTS4 ACVR1B JAK2 ADGRD1

1.24e-0419011350fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS4 LAMB1 ADCY5 KLHL23 ADGRD1

1.24e-0419011357be4341e2909101d756f14031c21e705eb45e69a
ToppCellwk_08-11-Epithelial-PNS-Schwann_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KIF13B HSPH1 GRIK2 ADAM12 MMP17

1.24e-0419011354a777d8aa19cadd3b61b023772df142421a89113
ToppCell10x5'v1-week_12-13-Lymphocytic_B-B_lineage-pro_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

JADE2 LRRC14B GBP4 TRIM38 ZNF292

1.27e-041911135054fa0493b00149313c243d39cf39a264044f074
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

KIF13B MYCBP2 SFI1 XPO1 ZNF292

1.27e-0419111359454f642c3621370fa23640b631301346b300950
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF13B GRIK2 DBH ADAM12 HES6

1.27e-041911135a53616c84178eb6c29b48662358765b082df3f97
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

KIF13B EXOC6 ACACB CP BMX

1.27e-041911135ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FMO2 LAMB1 CP SCUBE2 ADGRD1

1.27e-041911135997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCellhuman_hepatoblastoma-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ACACB CP AASS KLKB1 ADGRD1

1.30e-041921135e785135262f4c9cc66c403bf362bb34643b212c5
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

TTC28 HSPH1 DYRK1A ADGRD1 ZNF292

1.33e-041931135e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

ADAMTS4 LAMB1 ADCY5 KLHL23 ADGRD1

1.36e-0419411355e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EXOC6 FMO2 TTC28 INSR LAMA3

1.40e-0419511356bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 ADAM12 KLHL32 GLP1R MUC4

1.40e-04195113558b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CDKL2 ADCY5 SCUBE2 KLHL23 HES6

1.43e-041961135a4cc02ea41479d24044bd2ca6441f85d683c0ca9
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CDKL2 ADCY5 SCUBE2 KLHL23 HES6

1.43e-04196113550aaca81b593ff71790bb75403b2e4c3ab03a6d2
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PLB1 FMO2 LAMA3 CP USP54

1.46e-041971135b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellTracheal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 ADCY5 GYS2 HES6 MMP17

1.46e-04197113506e17c9ad53463eee1007280b3f3e8b0cf446cdc
ToppCellAT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

CP XPO1 AASS AGL MUC4

1.46e-0419711355e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCellCOPD-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

FAT4 FMO2 ADAMTS4 LAMB1 AASS

1.46e-041971135d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PLB1 GBP6 CP HES6 MUC4

1.46e-041971135861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Club|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FMO2 KIF26B CP USP54 MUC4

1.46e-04197113501e9505d947e5a5f005d1eab96301f84fc194809
ToppCellASK452-Epithelial-Type_1|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

FMO2 LAMA3 NCEH1 USP54 SEMA3E

1.46e-041971135dc0a6dca4af6b216357b06f67203274f8b2a8bb0
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 ADCY5 GLP1R KLHL23 SLC38A11

1.46e-041971135d1cb30ec4f3024541e9876c70bf63fe4d5c55bf1
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

KIF13B FAT4 KIF26B LAMB1 ADAM12

1.46e-041971135f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellBiopsy_Control_(H.)-Epithelial-SCGB3A2+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

FMO2 CP AASS USP54 MUC4

1.50e-0419811351fe51f4beca0eef4ff117e6edaa646e35c0f9629
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF845 ADCY5 ALDH1B1 TATDN1 SEMA3E

1.50e-041981135cc2b5b632e73e44bb60050f0db10d8f0dbb859fa
Diseaseclinical treatment

MYCBP2 DYRK1A APOB GBP4

1.55e-05411084EFO_0007056
Diseaseheart disease (biomarker_via_orthology)

CP JAK2 EP300

3.12e-05171083DOID:114 (biomarker_via_orthology)
DiseaseGrowth abnormality

TET3 ZNF292

3.97e-0531082C0262361
Diseaselung carcinoma (is_marker_for)

JAK2 MUC4

1.32e-0451082DOID:3905 (is_marker_for)
Diseaselung small cell carcinoma (is_implicated_in)

LAMA3 ACVR1B XPO5

1.46e-04281083DOID:5409 (is_implicated_in)
DiseaseCOVID-19, obesity

KLHL32 ATP2A1

2.75e-0471082EFO_0001073, MONDO_0100096
Diseaseeosinophil count

EXOC6 PLB1 RHBDF2 ADAMTS4 DYRK1A XPO1 JAK2 RRP12 HELZ2 CDYL2 SPIDR MMP17 TET3 ZNF292 IL9R

3.42e-04148810815EFO_0004842
Diseasecommon bile duct neoplasm (is_marker_for)

APOB MUC4

3.66e-0481082DOID:4608 (is_marker_for)
DiseaseMood Disorders

TBC1D25 GRIK2 DBH HES6 IL9R

3.92e-041681085C0525045
DiseaseAbnormality of the face

TET3 ZNF292

4.70e-0491082C4025871
Diseaseabdominal aortic calcification measurement

HDAC9 PIK3R4

5.86e-04101082EFO_0010272
Diseasepolycystic ovary syndrome, type 2 diabetes mellitus

ADCY5 SLC38A11

5.86e-04101082EFO_0000660, MONDO_0005148
Diseasehepatocellular carcinoma (biomarker_via_orthology)

CAD INSR JAK2 EP300

6.79e-041081084DOID:684 (biomarker_via_orthology)
Diseasepeptidyl-glycine alpha-amidating monooxygenase measurement

MYCBP2 KLKB1

7.14e-04111082EFO_0801871
Diseasehepatocellular carcinoma (implicated_via_orthology)

CAD INSR XPO1

7.77e-04491083DOID:684 (implicated_via_orthology)
Diseasediabetic retinopathy (implicated_via_orthology)

INSR EP300

1.54e-03161082DOID:8947 (implicated_via_orthology)
Diseaseautism spectrum disorder (is_implicated_in)

DYRK1A CYFIP1

1.54e-03161082DOID:0060041 (is_implicated_in)
Diseaselung non-small cell carcinoma (is_implicated_in)

XPO1 ACVR1B JAK2 XPO5

1.73e-031391084DOID:3908 (is_implicated_in)
Diseasewaist-hip ratio

APPBP2 TTC28 MYCBP2 INSR LAMB1 KLHL32 ADCY5 PRUNE1 SCUBE2 DSTYK CDYL2 ATP2A1

1.78e-03122610812EFO_0004343
Diseaseemphysema imaging measurement

MYCBP2 GRIK2 ALDH1B1 KLKB1

2.07e-031461084EFO_0007626
Diseaseglomerulonephritis (is_marker_for)

KLKB1 EP300

2.18e-03191082DOID:2921 (is_marker_for)
DiseaseDrugs used in diabetes use measurement

EXOC6 MYCBP2 JADE2 ADCY5 GLP1R

2.51e-032551085EFO_0009924
Diseaseesophagus squamous cell carcinoma (is_marker_for)

XPO1 JAK2 TET3

2.56e-03741083DOID:3748 (is_marker_for)
Diseasecarnosine measurement

GRIK2 KLKB1

3.48e-03241082EFO_0010470

Protein segments in the cluster

PeptideGeneStartEntry
IDGVDLCFFGMHVQE

EP300

1366

Q09472
FHNHEETKGLMDENC

ANKRD20A8P

501

Q5CZ79
AEAMHHQDCLLFATS

ADGRD1

446

Q6QNK2
EVFEGCFQDNMRHGH

ALS2

1121

Q96Q42
ACMVSIFNLDGMEHH

ACVR1B

51

P36896
CEGMAFLESHQFIHR

BMX

521

P51813
EHAVEQCHEALFFNM

ALDH1B1

301

P30837
AVDAMNKHGCQVHFG

GYS2

91

P54840
ESHDFVGCIMEFAVN

FAT4

4126

Q6V0I7
FCMYDADQHIIHDSV

AASS

376

Q9UDR5
NISVFGVHECAMQCH

ADAM12

651

O43184
HCFQALMDHGVKVAS

APPBP2

81

Q92624
HFTAAVQAMDCETHS

DYRK1A

541

Q13627
AAFHQDHMGLACYAL

ADCY5

291

O95622
EMETFEFLNICQVHG

BMS1

161

Q14692
THFMQCTEDNTHFEG

ATP2A1

871

O14983
AAMEGHLHCFKFLVS

ANKRD42

171

Q8N9B4
MHFLEENTLIHGNVC

JAK2

661

O60674
FAAGYIQCMHEVHTF

HES6

96

Q96HZ4
EFLQNDHCLGSHKMF

PIK3C2G

341

O75747
MAHESAEDLFHFNVG

KCTD19

6

Q17RG1
FVLIMNGCHIEIDAH

ACACB

836

O00763
FGMGNEVDVHAAFFH

CP

286

P00450
HAFCQAHSYDVLVAM

PRUNE1

271

Q86TP1
NGVMHVDECVEFHRL

CYFIP1

1116

Q7L576
GEHCEHLSMKLDAFF

MUC4

5356

Q99102
MPRCGHQEVDHFFCE

OR2B3

166

O76000
MAQHFSLAACDVVGF

NT5DC1

1

Q5TFE4
QCEVCETHSFSFHPM

LAMA3

1336

Q16787
GTHEVIFAFVMDEHA

GLP1R

361

P43220
ECFQHKNHTCLVFEM

HIPK1

256

Q86Z02
HSFIAQTCFGHGEAM

KIF26B

1296

Q2KJY2
AFMCETALHYIHDGI

GATD3B

241

A0A0B4J2D5
VDMGHSAFQVSACAF

HSPH1

201

Q92598
TAFHVTCAFDHGLEM

JADE2

331

Q9NQC1
AMVTAAFCHDIDHRG

PDE6A

591

P16499
DHFEDGFHGCMIFTS

NCEH1

371

Q6PIU2
NCNEHSISCHFDMAV

LAMB1

336

P07942
LNHTDMAFLADCAHA

LRRC14B

316

A6NHZ5
MAFLADCAHAAHLEV

LRRC14B

321

A6NHZ5
HAACEREAIAVFMEH

GBP4

371

Q96PP9
HAACEREAIAIFMEH

GBP6

356

Q6ZN66
FLNEASVMKGFTCHH

INSR

1071

P06213
HCHCLDIFINQAFDM

DSTYK

366

Q6XUX3
EIEKMCNFHHQGFVD

EXOC6

61

Q8TAG9
QIVLELHFSHCAAMG

POMT1

121

Q9Y6A1
PFCAELLHHDFFQMD

CDKL2

276

Q92772
MNTNFFHESGLEAHV

APOB

901

P04114
AFTAAHELGHVFNML

ADAMTS4

356

O75173
IDNCIGMHSFAEFHV

KLHL23

136

Q8NBE8
GMHSFAEFHVCPELE

KLHL23

141

Q8NBE8
GNEALVHHMEVFQCA

DBH

256

P09172
RQIMDSSECFHAAHF

DNAAF9

781

Q5TEA3
AFMCETALHYIHDGI

GATD3

241

P0DPI2
MEEYHRHCDEVGFNA

DYNLT3

1

P51808
QSAVFDAVMVCSGHH

FMO2

136

Q99518
CHMNIFQHLAFSDVD

KLKB1

201

P03952
TKHTFTNHMVFQFDC

COPG1

651

Q9Y678
GHHAEESTAMGFCFF

HDAC5

831

Q9UQL6
GHHAEESTAMGFCFF

HDAC9

781

Q9UKV0
GKEFHVIFDCSHEMA

GRIK2

221

Q13002
ENHCASSEHAQMVAF

HELZ2

56

Q9BYK8
FFAHVFMVLDEPHHC

SLC22A13

36

Q9Y226
FMLAHDGHNCLDVDE

SCUBE1

106

Q8IWY4
GFMLAHDGHNCLDVD

SCUBE2

116

Q9NQ36
VSFDFHEHCRGMKFE

INPP5F

406

Q9Y2H2
QAVGVMSFAFICHHN

SLC38A11

166

Q08AI6
AHFFQEKVSHGVCMP

LGSN

106

Q5TDP6
HSDGAISCHDMFDFL

PAFAH1B2

181

P68402
CLAQMFFVHGFTGVE

OR52N5

106

Q8NH56
KEPHCMVVFDHCNEF

KIF13B

916

Q9NQT8
CAEEAAQFEMAEEHH

SFI1

366

A8K8P3
MSCEEHGEQFHLFCE

TRIM38

91

O00635
MFLHCRNSHAEFLDI

TATDN1

146

Q6P1N9
ILAVMDHEGHAFVCF

TBC1D25

341

Q3MII6
DAHGMDLFAVAVHEF

MMP17

236

Q9ULZ9
DHAPLQQFFVVMEHC

RUFY1

141

Q96T51
EHMAAFGVFGLCQIH

STT3A

266

P46977
SCGFHHSVVLMENGD

MYCBP2

946

O75592
DNFTITFHHCMSGRE

IL9R

116

Q01113
DCFHFSDRGHAEMAI

PLB1

1346

Q6P1J6
VTACAMQAFHSLFHA

RRP12

341

Q5JTH9
IIAMETHGAHCFNAA

SDSL

196

Q96GA7
HTTLEHSDCAFMVDN

TUBA4B

131

Q9H853
LHCEEFIDEFNGLHM

CDYL2

46

Q8N8U2
IENDCIQDFMFHGIH

NCAPG2

281

Q86XI2
HVMHQICAQTDFARF

NLN

501

Q9BYT8
HIGDFCFQEMEKDIH

ZNF845

81

Q96IR2
DQKEDGCVVDMHHFN

PIK3R4

1091

Q99570
GCVVDMHHFNSGAQS

PIK3R4

1096

Q99570
EFMHETHDGVQDMAC

XPO1

571

O14980
ALIMVGFHFLHCFEE

ZDHHC3

186

Q9NYG2
ILCDGLTDAFHNCHM

ACAT2

146

Q9BWD1
LTDAFHNCHMGITAE

ACAT2

151

Q9BWD1
QDACGMFGEVHLEFT

SPIDR

521

Q14159
LHHYLQVEGMEESCF

TUBE1

426

Q9UJT0
MMIHGFQSSHRDFCF

TIPRL

1

O75663
CFIIEHKGDNFIMHS

STOX2

411

Q9P2F5
MCGLILEDVFHFADH

ZNF587

96

Q96SQ5
IREGFSCHVFHLTMA

FAM170A

251

A1A519
MCGLILEDVFHFADH

ZNF417

96

Q8TAU3
AHEKLMENGSCELHF

ZNF292

136

O60281
HDGCMASLVHLAFQI

XPO5

1086

Q9HAV4
ESVDVHCFGHLLYEM

PXK

331

Q7Z7A4
VTACMDFCAHAHKDQ

TET3

1066

O43151
NMAVIDCFASDHAPH

CAD

1676

P27708
AMGDFENAVQCHEQH

TTC28

366

Q96AY4
NGEIFSEHSCLNAHM

ZNF121

16

P58317
AMNTAAFTHCFIHRE

ZMYM6

1001

O95789
FFQHHQFMCSECGSL

ZNF526

51

Q8TF50
VAQVRFHHCDMYGSA

SEMA3E

511

O15041
ARSNHTGFLHMDCEI

RHBDF2

581

Q6PJF5
DCGKAFSQNMHLIVH

ZNF71

246

Q9NQZ8
EMGFHHATQACLELL

ZNF195

76

O14628
CFAMATQTSHVFHGQ

VWA3A

11

A6NCI4
VFHGQENMFLENHCI

VWA3A

21

A6NCI4
AAECFENLLMRIHFH

USP54

121

Q70EL1
IAHALFMDITHDNEC

AGL

616

P35573
RSHHCVAVMGDFLFV

KLHL32

336

Q96NJ5