Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioninsulin-like growth factor I binding

LRP2 ITGB3

3.64e-0413442GO:0031994
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMA2 LAMC2 RELN SSPOP

7.70e-04188444GO:0005201
GeneOntologyMolecularFunctioninsulin-like growth factor binding

LRP2 ITGB3

7.92e-0419442GO:0005520
GeneOntologyMolecularFunctioncargo receptor activity

LRP2 SCARF2 MEGF10

8.69e-0485443GO:0038024
GeneOntologyBiologicalProcessregulation of AMPA receptor activity

RELN SHISA7 SHISA8

1.88e-0525433GO:2000311
GeneOntologyBiologicalProcesscell morphogenesis

LRP2 LAMA2 LAMC2 LAMC3 RELN RIMS1 ITGB3 ZMYM4 TNN PTK7 CRB1

2.41e-0511944311GO:0000902
GeneOntologyBiologicalProcessaxon guidance

LRP2 LAMA2 LAMC2 LAMC3 RELN PTK7

2.62e-05285436GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

LRP2 LAMA2 LAMC2 LAMC3 RELN PTK7

2.67e-05286436GO:0097485
GeneOntologyBiologicalProcesscell projection morphogenesis

LRP2 LAMA2 LAMC2 LAMC3 RELN RIMS1 ITGB3 TNN PTK7

4.20e-05826439GO:0048858
GeneOntologyBiologicalProcessaxonogenesis

LRP2 LAMA2 LAMC2 LAMC3 RELN TNN PTK7

1.54e-04566437GO:0007409
GeneOntologyBiologicalProcesspost-embryonic animal morphogenesis

ATRX CRB1

1.89e-0410432GO:0009886
GeneOntologyBiologicalProcessregulation of neurotransmitter receptor activity

RELN SHISA7 SHISA8

2.17e-0456433GO:0099601
GeneOntologyBiologicalProcessneuron projection morphogenesis

LRP2 LAMA2 LAMC2 LAMC3 RELN RIMS1 TNN PTK7

2.18e-04802438GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

LRP2 LAMA2 LAMC2 LAMC3 RELN RIMS1 TNN PTK7

2.52e-04819438GO:0120039
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LRP2 LAPTM4B

2.77e-0412432GO:1905165
GeneOntologyBiologicalProcessaxon development

LRP2 LAMA2 LAMC2 LAMC3 RELN TNN PTK7

3.33e-04642437GO:0061564
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

LRP2 LAPTM4B

3.80e-0414432GO:1904350
GeneOntologyCellularComponentextracellular matrix

LAMA2 LAMC2 LAMC3 RELN COL26A1 SSPOP TNN OTOG

4.95e-05656438GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMA2 LAMC2 LAMC3 RELN COL26A1 SSPOP TNN OTOG

5.05e-05658438GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMA2 LAMC2 LAMC3 RELN COL26A1 SSPOP TNN

9.45e-05530437GO:0062023
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMA2 ITGB3 TNN

2.43e-0459433GO:0098636
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMA2 TNN

5.51e-0417432GO:0098637
GeneOntologyCellularComponentdendritic spine membrane

SHISA7 SHISA8

6.19e-0418432GO:0032591
GeneOntologyCellularComponentdendrite

LRP2 CNTNAP4 LAMA2 RELN SHISA7 TNN SHISA8

1.70e-03858437GO:0030425
GeneOntologyCellularComponentdendritic tree

LRP2 CNTNAP4 LAMA2 RELN SHISA7 TNN SHISA8

1.72e-03860437GO:0097447
GeneOntologyCellularComponentAMPA glutamate receptor complex

SHISA7 SHISA8

1.73e-0330432GO:0032281
GeneOntologyCellularComponentbasement membrane

LAMA2 LAMC2 LAMC3

2.02e-03122433GO:0005604
GeneOntologyCellularComponentapical plasma membrane

LRP2 PAPPA2 ITGB3 CRB1 OTOG

3.12e-03487435GO:0016324
GeneOntologyCellularComponentsomatodendritic compartment

LRP2 CNTNAP4 LAMA2 RELN SHISA7 TNN PTK7 SHISA8

3.19e-031228438GO:0036477
GeneOntologyCellularComponentionotropic glutamate receptor complex

SHISA7 SHISA8

3.87e-0345432GO:0008328
GeneOntologyCellularComponentneurotransmitter receptor complex

SHISA7 SHISA8

4.76e-0350432GO:0098878
GeneOntologyCellularComponentdendrite membrane

SHISA7 SHISA8

5.93e-0356432GO:0032590
GeneOntologyCellularComponentsynaptic membrane

CNTNAP4 RIMS1 ITGB3 SHISA7 SHISA8

6.66e-03583435GO:0097060
GeneOntologyCellularComponentapical part of cell

LRP2 PAPPA2 ITGB3 CRB1 OTOG

7.09e-03592435GO:0045177
MousePhenoabnormal basal lamina morphology

LAMA2 LAMC2 CRIM1

3.12e-076363MP:0004273
MousePhenoabnormal somatic sensory system morphology

LAMA2 LAMC3 RELN CRIM1 MEGF11 MEGF10 PTK7 CRB1 OTOG

5.34e-05702369MP:0000959
DomainEGF-like_dom

ADGRE4P LRP2 CNTNAP4 LAMA2 LAMC2 LAMC3 RELN SCARF2 MEGF11 TNN MEGF10 CRB1 OTOG

1.10e-142494413IPR000742
DomainEGF_1

LRP2 CNTNAP4 LAMA2 LAMC2 LAMC3 RELN SSPOP SCARF2 ITGB3 MEGF11 TNN MEGF10 CRB1

1.50e-142554413PS00022
DomainEGF_2

LRP2 CNTNAP4 LAMA2 LAMC2 LAMC3 RELN SSPOP SCARF2 ITGB3 MEGF11 TNN MEGF10 CRB1

2.47e-142654413PS01186
DomainEGF

ADGRE4P LRP2 CNTNAP4 LAMA2 LAMC2 LAMC3 RELN SCARF2 MEGF11 TNN MEGF10 CRB1

1.76e-132354412SM00181
DomainEGF-like_CS

LRP2 CNTNAP4 LAMA2 LAMC2 LAMC3 RELN SCARF2 ITGB3 MEGF11 TNN MEGF10 CRB1

6.11e-132614412IPR013032
DomainEGF_3

ADGRE4P LRP2 CNTNAP4 RELN SSPOP SCARF2 MEGF11 TNN MEGF10 CRB1 OTOG

5.27e-122354411PS50026
DomainEGF_extracell

LRP2 RELN SCARF2 ITGB3 MEGF11 TNN MEGF10

8.59e-1160447IPR013111
DomainEGF_2

LRP2 RELN SCARF2 ITGB3 MEGF11 TNN MEGF10

8.59e-1160447PF07974
DomainLaminin_EGF

LAMA2 LAMC2 LAMC3 SCARF2 MEGF11 MEGF10

1.85e-1035446PF00053
DomainEGF_Lam

LAMA2 LAMC2 LAMC3 SCARF2 MEGF11 MEGF10

1.85e-1035446SM00180
DomainLaminin_EGF

LAMA2 LAMC2 LAMC3 SCARF2 MEGF11 MEGF10

3.13e-1038446IPR002049
DomainEMI

COL26A1 SSPOP MEGF11 MEGF10

6.23e-0817444PS51041
DomainGrowth_fac_rcpt_

LRP2 LAMC2 LAMC3 CRIM1 SCARF2 TNN CRB1

7.33e-08156447IPR009030
DomainLAMININ_IVA

LAMA2 LAMC2 LAMC3

6.78e-078443PS51115
DomainLaminin_B

LAMA2 LAMC2 LAMC3

6.78e-078443PF00052
DomainLamB

LAMA2 LAMC2 LAMC3

6.78e-078443SM00281
DomainLaminin_IV

LAMA2 LAMC2 LAMC3

6.78e-078443IPR000034
Domain-

CNTNAP4 LAMA2 LAMC3 SUCO SSPOP

7.66e-07734452.60.120.260
DomainShisa

SHISA7 SHISA8 SHISA3

1.01e-069443PF13908
DomainShisa

SHISA7 SHISA8 SHISA3

1.01e-069443IPR026910
DomainGalactose-bd-like

CNTNAP4 LAMA2 LAMC3 SUCO SSPOP

2.70e-0694445IPR008979
DomainTIL_dom

LRP2 SSPOP OTOG

4.36e-0614443IPR002919
DomainEMI_domain

COL26A1 MEGF11 MEGF10

6.69e-0616443IPR011489
DomainVWC_out

CRIM1 SSPOP OTOG

1.15e-0519443SM00215
DomainWBP1-like

WBP1 WBP1L

3.24e-054442IPR021684
DomainWBP-1

WBP1 WBP1L

3.24e-054442PF11669
DomainhEGF

MEGF11 MEGF10 CRB1

3.84e-0528443PF12661
DomainEGF_LAM_2

LAMA2 LAMC2 LAMC3

4.74e-0530443PS50027
DomainEGF_LAM_1

LAMA2 LAMC2 LAMC3

4.74e-0530443PS01248
Domain-

PAPPA2 CNTNAP4 LAMA2 CRB1

7.30e-05954442.60.120.200
DomainLAM_G_DOMAIN

CNTNAP4 LAMA2 CRB1

9.71e-0538443PS50025
DomainLaminin_G_2

CNTNAP4 LAMA2 CRB1

1.13e-0440443PF02210
DomainVWF_dom

CRIM1 SSPOP OTOG

1.31e-0442443IPR001007
DomainLamG

CNTNAP4 LAMA2 CRB1

1.51e-0444443SM00282
DomainConA-like_dom

PAPPA2 CNTNAP4 LAMA2 TRIM50 CRB1

1.58e-04219445IPR013320
DomainEGF

LRP2 CNTNAP4 ITGB3 CRB1

2.18e-04126444PF00008
DomainLaminin_G

CNTNAP4 LAMA2 CRB1

3.44e-0458443IPR001791
DomainTIL

SSPOP OTOG

3.53e-0412442PF01826
DomainC8

SSPOP OTOG

3.53e-0412442PF08742
DomainUnchr_dom_Cys-rich

SSPOP OTOG

4.16e-0413442IPR014853
DomainC8

SSPOP OTOG

4.16e-0413442SM00832
DomainLAMININ_NTER

LAMA2 LAMC3

6.37e-0416442PS51117
DomainVWFD

SSPOP OTOG

6.37e-0416442PS51233
DomainLaminin_N

LAMA2 LAMC3

6.37e-0416442PF00055
DomainVWD

SSPOP OTOG

6.37e-0416442SM00216
DomainVWF_type-D

SSPOP OTOG

6.37e-0416442IPR001846
DomainLaminin_N

LAMA2 LAMC3

6.37e-0416442IPR008211
DomainVWD

SSPOP OTOG

6.37e-0416442PF00094
DomainLamNT

LAMA2 LAMC3

6.37e-0416442SM00136
DomainFA58C

CNTNAP4 SSPOP

1.11e-0321442SM00231
DomainFA58C_3

CNTNAP4 SSPOP

1.11e-0321442PS50022
DomainFA58C_1

CNTNAP4 SSPOP

1.11e-0321442PS01285
DomainFA58C_2

CNTNAP4 SSPOP

1.11e-0321442PS01286
DomainF5_F8_type_C

CNTNAP4 SSPOP

1.45e-0324442PF00754
DomainFA58C

CNTNAP4 SSPOP

1.45e-0324442IPR000421
DomainCys_knot_C

SSPOP OTOG

1.57e-0325442IPR006207
DomainCTCK_2

SSPOP OTOG

1.57e-0325442PS01225
DomainEGF_CA

ADGRE4P LRP2 CRB1

1.63e-0399443PS01187
DomainASX_HYDROXYL

ADGRE4P LRP2 CRB1

1.68e-03100443PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

ADGRE4P LRP2 CRB1

1.99e-03106443IPR000152
DomainFBG

CNTNAP4 TNN

2.11e-0329442SM00186
Domain-

CNTNAP4 TNN

2.26e-03304423.90.215.10
DomainFibrinogen_a/b/g_C_1

CNTNAP4 TNN

2.26e-0330442IPR014716
DomainFibrinogen_a/b/g_C_dom

CNTNAP4 TNN

2.57e-0332442IPR002181
DomainFIBRINOGEN_C_2

CNTNAP4 TNN

2.57e-0332442PS51406
DomainFIBRINOGEN_C_1

CNTNAP4 TNN

2.57e-0332442PS00514
DomainZnf_FYVE-rel

RIMS1 ZFYVE1

2.90e-0334442IPR017455
DomainEGF-like_Ca-bd_dom

ADGRE4P LRP2 CRB1

3.10e-03124443IPR001881
DomainVWFC_1

CRIM1 SSPOP

3.25e-0336442PS01208
DomainVWC

CRIM1 SSPOP

3.61e-0338442SM00214
DomainZnf_FYVE

RIMS1 ZFYVE1

3.61e-0338442IPR000306
DomainVWFC_2

CRIM1 SSPOP

3.61e-0338442PS50184
Domain-

LRP2 HHIPL2

3.80e-03394422.120.10.30
DomainLDLR_class-A_CS

LRP2 SSPOP

4.00e-0340442IPR023415
DomainZF_FYVE

RIMS1 ZFYVE1

4.00e-0340442PS50178
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMA2 LAMC2 LAMC3 RELN ITGB3 TNN

7.82e-0984266M7098
PathwayWP_FOCAL_ADHESION

LAMA2 LAMC2 LAMC3 RELN ITGB3 TNN

9.28e-07187266MM15913
PathwayKEGG_FOCAL_ADHESION

LAMA2 LAMC2 LAMC3 RELN ITGB3 TNN

1.34e-06199266M7253
PathwayWP_FOCAL_ADHESION

LAMA2 LAMC2 LAMC3 RELN ITGB3 TNN

1.34e-06199266M39402
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMA2 LAMC2 LAMC3 ITGB3

3.86e-0659264M27218
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LAMA2 LAMC2 LAMC3 COL26A1 ITGB3 TNN

1.42e-05300266M610
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

LAMA2 LAMC2 LAMC3 RELN ITGB3 TNN

1.48e-05302266M39719
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA2 LAMC2 LAMC3

2.19e-0530263M27772
PathwayREACTOME_LAMININ_INTERACTIONS

LAMA2 LAMC2 LAMC3

2.19e-0530263M27216
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

LAMA2 LAMC2 LAMC3 RELN ITGB3 TNN

2.27e-05326266MM15917
PathwayWP_PI3KAKT_SIGNALING

LAMA2 LAMC2 LAMC3 RELN ITGB3 TNN

2.84e-05339266M39736
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA2 LAMC2 LAMC3

5.67e-0541263M27778
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMA2 LAMC2 LAMC3

8.02e-0546263M239
PathwayPID_INTEGRIN4_PATHWAY

LAMA2 LAMC2

1.78e-0411262M158
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMA2 ITGB3 TNN

3.58e-0476263M27219
PathwayREACTOME_SIGNALING_BY_MET

LAMA2 LAMC2 LAMC3

4.01e-0479263M27643
PathwayKEGG_SMALL_CELL_LUNG_CANCER

LAMA2 LAMC2 LAMC3

4.81e-0484263M3228
PathwayWP_SMALL_CELL_LUNG_CANCER

LAMA2 LAMC2 LAMC3

7.10e-0496263M39834
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA2 LAMC2

1.67e-0333262M39503
Pubmed

Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.

LAMA2 LAMC2 LAMC3

2.25e-071044311784026
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMA2 LAMC2 LAMC3

3.10e-071144321524702
Pubmed

Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.

LAMA2 LAMC2 LAMC3

3.10e-071144323472759
Pubmed

Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning.

LAMA2 LAMC2 LAMC3

4.12e-071244326794322
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMA2 LAMC2 LAMC3

8.50e-071544315895400
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

LAMA2 LAMC2 LAMC3

1.05e-061644317601529
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMA2 LAMC2 LAMC3

1.52e-061844311311202
Pubmed

The mammalian Ced-1 ortholog MEGF10/KIAA1780 displays a novel adhesion pattern.

MEGF11 MEGF10

1.56e-06244217498693
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

LRP2 LAMA2 SSPOP CRB1

2.03e-067144433541421
Pubmed

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

LAMA2 LAMC2 LAMC3

2.12e-062044322911573
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

LAMA2 LAMC2 LAMC3 COL26A1

3.12e-067944418757743
Pubmed

Laminin isoforms in development and disease.

LAMA2 LAMC2

4.69e-06344217426950
Pubmed

Characterization and expression of the laminin gamma3 chain: a novel, non-basement membrane-associated, laminin chain.

LAMA2 LAMC3

4.69e-06344210225960
Pubmed

Laminin isoforms containing the gamma3 chain are unable to bind to integrins due to the absence of the glutamic acid residue conserved in the C-terminal regions of the gamma1 and gamma2 chains.

LAMC2 LAMC3

4.69e-06344218697739
Pubmed

Auxiliary subunits of the CKAMP family differentially modulate AMPA receptor properties.

SHISA7 SHISA8

4.69e-06344226623514
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

LAMA2 LAMC2 LAMC3

4.81e-062644324742657
Pubmed

MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons.

PAPPA2 MEGF11 MEGF10

1.20e-053544322407321
Pubmed

Overexpression of malignancy-associated laminins and laminin receptors by angiotropic human melanoma cells in a chick chorioallantoic membrane model.

LAMC2 ITGB3

1.56e-05544219469865
Pubmed

Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor.

MEGF11 MEGF10

3.27e-05744219915564
Pubmed

A new nomenclature for the laminins.

LAMC2 LAMC3

3.27e-0574427921537
Pubmed

Unexpected diversity in Shisa-like proteins suggests the importance of their roles as transmembrane adaptors.

WBP1L SHISA3

3.27e-05744222120523
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMA2 LAMC2

4.36e-0584428872465
Pubmed

Isolation of novel mouse genes that were differentially expressed in W/W(V) mouse fundus.

TNN PTK7

6.99e-051044215065000
Pubmed

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.

LAMA2 LAMC2

6.99e-05104429034910
Pubmed

Basement membrane deposition of nidogen 1 but not nidogen 2 requires the nidogen binding module of the laminin gamma1 chain.

LAMC2 LAMC3

8.54e-051144221084308
Pubmed

A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

LRP2 RELN

8.54e-051144223968836
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CDC42BPG RIMS1 COL26A1 TESMIN ATRX TMEM255B SSPOP ZMYM4 PTK7

8.61e-05148944928611215
Pubmed

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.

LAMA2 LAMC2

1.02e-04124429396756
Pubmed

The γ3 chain of laminin is widely but differentially expressed in murine basement membranes: expression and functional studies.

LAMC2 LAMC3

1.21e-041344222222602
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CDC42BPG LAMC2 ATRX ITGB3 PTK7 SLC25A10

1.61e-0465044638777146
Pubmed

Laminin alpha5 chain is required for intestinal smooth muscle development.

LAMA2 LAMC2

1.63e-041544212921739
Pubmed

SOX5 controls the sequential generation of distinct corticofugal neuron subtypes.

RELN CRIM1

1.63e-041544218215621
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

LAMA2 LAMC2

1.63e-04154429264260
Pubmed

Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch.

MEGF11 MEGF10

1.63e-041544231812516
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

LAMA2 LAMC2

2.36e-041844214730302
Pubmed

Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon.

RELN CRB1

2.93e-042044226802325
Pubmed

Schwann cell myelination requires integration of laminin activities.

LAMA2 LAMC3

3.24e-042144222767514
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

LAMA2 LAMC3

3.56e-042244235245678
Pubmed

Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53.

RELN ATRX

3.56e-042244219020049
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

FHL3 SCARF2 ITGB3 PTK7

4.63e-0428544421423176
Pubmed

Osteopotentia regulates osteoblast maturation, bone formation, and skeletal integrity in mice.

SUCO ITGB3

5.38e-042744220440000
Pubmed

Genetic link between renal birth defects and congenital heart disease.

LRP2 PTK7

5.79e-042844227002738
Pubmed

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.

LAMC3 CRIM1

5.79e-042844233953184
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

CNTNAP4 SSPOP MEGF10

6.04e-0413044312421765
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

LAMA2 LAMC2

6.21e-042944222613833
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ATRX FHL3 MEGF11 FAM221A MEGF10

6.88e-0456044521653829
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

LAMA2 LAMC2

1.18e-034044227068110
CytobandEnsembl 112 genes in cytogenetic band chr1q25

PAPPA2 LAMC2 TNN

5.61e-04167443chr1q25
GeneFamilyShisa family members

SHISA7 SHISA8 SHISA3

1.85e-078283742
GeneFamilyLaminin subunits

LAMA2 LAMC2 LAMC3

7.25e-0712283626
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SCARF2 MEGF10

7.93e-04272821253
CoexpressionNABA_CORE_MATRISOME

LAMA2 LAMC2 LAMC3 RELN CRIM1 COL26A1 SSPOP TNN OTOG

4.75e-10270439MM17057
CoexpressionNABA_CORE_MATRISOME

LAMA2 LAMC2 LAMC3 RELN CRIM1 COL26A1 SSPOP TNN OTOG

5.58e-10275439M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA2 LAMC2 LAMC3 RELN CRIM1 SSPOP TNN OTOG

8.00e-10191438MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA2 LAMC2 LAMC3 RELN CRIM1 SSPOP TNN OTOG

9.82e-10196438M3008
CoexpressionNABA_MATRISOME

PAPPA2 LAMA2 LAMC2 LAMC3 RELN CRIM1 COL26A1 SSPOP MEGF11 TNN MEGF10 OTOG

4.99e-0810084312MM17056
CoexpressionNABA_MATRISOME

PAPPA2 LAMA2 LAMC2 LAMC3 RELN CRIM1 COL26A1 SSPOP MEGF11 TNN MEGF10 OTOG

6.06e-0810264312M5889
CoexpressionNABA_BASEMENT_MEMBRANES

LAMA2 LAMC2 LAMC3

3.89e-0540433M5887
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 LAMC3 RELN MEGF11 SHISA8

9.80e-07182445420a8fd30543e37a66ba0786215d056d308660d0
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 CNTNAP4 RELN SSPOP OTOG

1.03e-06184445ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 CNTNAP4 RELN SSPOP OTOG

1.03e-061844452cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 CNTNAP4 RELN SSPOP OTOG

1.03e-061844452b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PAPPA2 CNTNAP4 RELN COL26A1 FHL3

1.27e-06192445d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LAMC2 MEGF11 LAPTM4B PTK7

1.56e-0620044533b7af6c50e65dc1bdf429572574ed072f8bc29f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LAMC2 MEGF11 LAPTM4B PTK7

1.56e-06200445d9dab2aed11e45c60d11ff0c5af1f2fbb9cb45d8
ToppCellCOVID-19-kidney-Mito-rich_Int|kidney / Disease (COVID-19 only), tissue and cell type

CNTNAP4 LAMA2 LAMC3 RELN

8.01e-0612944457b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP4 CDC42BPG RELN LAPTM4B

1.74e-05157444741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 CNTNAP4 LAMA2 CRB1

1.87e-05160444c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 CNTNAP4 LAMA2 CRB1

1.87e-0516044425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMC3 RELN MEGF11 SHISA8

2.16e-05166444688e3c01ffcec01eb7027df6f3bde8fecfb50479
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LAMC2 RIMS1 MEGF11

2.48e-05172444bd73fd3520064d430a153cfdd5c2858b6c184c59
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LAMC2 RIMS1 MEGF11

2.48e-0517244447ee78ed3ba6516dad8f12dbf70bca5ed1c60aff
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LAMC2 RIMS1 MEGF11

2.60e-05174444583955b4db442ba0583e2312af242f050547f9d6
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN FHL3 TMEM255B ITGB3

2.72e-051764445d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCellfacs-Aorta|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 SSPOP OTOG SHISA3

2.72e-051764440b3491451be02c18a16cdb875645be47eb867a7f
ToppCell356C-Endothelial_cells-Endothelial-D|356C / Donor, Lineage, Cell class and subclass (all cells)

RIMS1 CRIM1 TMEM255B ITGB3

2.78e-05177444a0b172f40e0df97a288a5549ae7066697ad469b3
ToppCell356C-Endothelial_cells-Endothelial-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

RIMS1 CRIM1 TMEM255B ITGB3

2.78e-05177444ab8f09e118e4df696b0b4d33f013da020bdbd351
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 LAMC3 RELN MEGF11

2.97e-05180444b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCelldroplet-Lung-LUNG-1m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LAMC2 SHISA7 SLC25A10

3.10e-05182444c1e0be27064e14043b78ae501b02d4e9542267a3
ToppCelldroplet-Lung-LUNG-1m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LAMC2 SHISA7 SLC25A10

3.10e-051824443c9b4869d357884ae4bcd22a9872faf83a5cfc6d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 LAMC3 CBFA2T3 CRIM1

3.17e-051834448a799807fbf24456a9811e0c64068187940a2f71
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 LAMC3 CBFA2T3 CRIM1

3.23e-05184444327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 LAMC3 RELN MEGF11

3.30e-05185444487fa382232564f075960899d50afa0edae5d258
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 LAMC2 SCARF2 PTK7

3.30e-05185444355b03c7ea438681e11a2b872c798c9ea26e1486
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 LAMC3 RELN SHISA8

3.30e-05185444cefd81adb480c027545a5c78dcd05669783717f4
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 LAMC3 CBFA2T3 CRIM1

3.37e-05186444888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP4 RELN MEGF11 SHISA8

3.44e-05187444ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

LAMA2 TMEM255B SCARF2 TNN

3.52e-05188444c90669b51e1902fe7726555290c91c92a911df83
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL26A1 TMEM255B MEGF11 PTK7

3.52e-05188444053c251d3ddbeb866f34565aefca4535517b4387
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA2 LAMC3 CBFA2T3 CRIM1

3.52e-05188444ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL26A1 TMEM255B MEGF11 PTK7

3.52e-051884447471c194276161422326647f09022e94f3d1640c
ToppCell(2)_Fibroblasts-(22)_Fibro-3|World / Cell class and subclass of bone marrow stroma cells in homeostatis

LAMA2 RELN COL26A1 SCARF2

3.67e-051904443aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 LAMC3 CBFA2T3 CRIM1

3.67e-05190444106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 LAMC3 CBFA2T3 CRIM1

3.74e-05191444716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 LAMC3 CBFA2T3 CRIM1

3.74e-051914441626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 RELN SCARF2 ITGB3

3.98e-05194444415801a3dfacf05f2b603fb424df3d045190a812
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 RELN SCARF2 ITGB3

3.98e-05194444256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 RELN SCARF2 ITGB3

3.98e-051944447942bc83c1bdca687795b91aa232824d603f9b09
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN CRIM1 COL26A1 ITGB3

4.14e-0519644434e79918a448f6c19b87e1b1ce13c012b24be1f8
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN CRIM1 COL26A1 ITGB3

4.14e-051964448f82e01ca50aa4cd6149547505b4474a02fad618
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LAMA2 LAMC3 COL26A1 TNN

4.22e-0519744444cd1ece3633a31e8c9b667cd3cbc2749c06f478
ToppCell(2)_Fibroblasts-(22)_Fibro-3|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

LAMA2 RELN COL26A1 SCARF2

4.22e-05197444d9021bab82403e566ec10f78acb227c0f80b88fe
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 LAMC2 COL26A1 MEGF10

4.30e-051984445e70246a9ce199cb2fb5379912b8ab59456219e4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LAMC2 COL26A1 PTK7

4.39e-051994442e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LAMC2 LAPTM4B PTK7

4.48e-05200444741e59c68ae4a3a7be830e98771a14f920c9e883
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LAMA2 LAMC3 CBFA2T3 CRIM1

4.48e-052004440c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAMA2 LAMC3 CBFA2T3 CRIM1

4.48e-0520044494f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LAMC2 LAPTM4B PTK7

4.48e-05200444ae91dc047dc80560ba298d8d21a772154fa2775d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LAMC2 LAPTM4B PTK7

4.48e-0520044455b7b17f2d413b9ebb262ef8bd210ef45618a7f3
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP4 LAMC3 RELN MEGF11

4.48e-0520044453d5e427f0cbf5cf0b63efe4ec01da302f555704
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMA2 LAMC3 CBFA2T3 CRIM1

4.48e-05200444522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Thalamus / BrainAtlas - Mouse McCarroll V32

SSPOP SHISA8 SHISA3

6.31e-05784435b45aacaff2a2b98c4ef8e7ac51ad482a69a1d8b
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)|Thalamus / BrainAtlas - Mouse McCarroll V32

SSPOP SHISA8 SHISA3

6.31e-0578443afed2f358c8a33889931bc5ad8cb24f92323e6f8
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-5|TCGA-Stomach / Sample_Type by Project: Shred V9

CLPSL2 SHISA7 SLC25A10

1.57e-041064434bee154c8b984338c06f73bd6e3fb26abce0bd72
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTNAP4 RELN COL26A1

2.74e-0412844391072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Acinar_Adenocarcinoma-7|TCGA-Lung / Sample_Type by Project: Shred V9

TRIM50 ITGB3 SHISA3

2.86e-041304430219d0d5d21df08f816569c7eb34f1bfa095d29a
ToppCellPBMC-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

CRIM1 SCARF2 PTK7

3.06e-04133443e53fbd69775a4bff61de82557342f7ac80915c4d
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-|Striatum / BrainAtlas - Mouse McCarroll V32

PAPPA2 CDC42BPG LAMC3

3.13e-04134443a3547a68012d879d4dfe80394eace70808722e43
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)|Striatum / BrainAtlas - Mouse McCarroll V32

PAPPA2 CDC42BPG LAMC3

3.13e-041344439458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WBP1 RELN FAM221A

3.41e-04138443611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PAPPA2 TMEM255B ITGB3

3.63e-04141443a32947b13e888850c979a54c137512e4b96d2f36
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PAPPA2 TMEM255B ITGB3

3.63e-041414432cb651d63466fdcce011d1dd8de409ef439d03e7
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RIMS1 CRIM1 MEGF11

3.78e-0414344339060dc1d87505a16e2df95140087c731f099570
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-MyoFB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

RIMS1 TESMIN TNN

3.94e-04145443ac41c6c02b7d78162b86222983688f54d04ac47d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP4 RELN LAPTM4B

4.18e-041484434d43efee96a6493abd78e9ca41aab73db0c80626
ToppCellClub_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

RIMS1 SHISA8 HHIPL2

4.27e-0414944381c813588bb5efb7b31141a75d387210dcb76094
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 LAMC3 PTK7

4.35e-041504437a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 LAMC3 PTK7

4.35e-04150443e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
ToppCellTCGA-Breast|World / Sample_Type by Project: Shred V9

CLPSL2 TESMIN TNN

4.35e-0415044308686ba1acac5c58667bf62e2af84c691d6bbdfb
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CDC42BPG SCARF2 SHISA8

4.52e-04152443595afcfa8b161e291fcaf2afc7336bac9b6fae0f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN CRIM1 COL26A1

4.52e-041524438ff5a178a8f3550d89a003c0858820aab3773386
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WBP1 LAMC3 TMEM255B

4.61e-04153443ee6f4770c6e35d59bdeec5b0ecb10119fa8c3ca5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WBP1 LAMC3 TMEM255B

4.61e-0415344390cd6efda83c0b4b80eae2c90e7ff45dfd936dc2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WBP1 LAMC3 TMEM255B

4.61e-04153443a35149a0c8b4ec9ad27cc4b3d34fba3b8714a6a2
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CDC42BPG SCARF2 SHISA8

4.79e-04155443216a240bfb82cdefc59e2f342689dbaaacb7c184
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

LAMA2 LAMC3 TNN

4.79e-041554431882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 LAMC3 CBFA2T3

4.88e-041564436365b69ede98bc866e996bc52736b00401aacf6f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TAAR8 TMEM255B SHISA3

4.88e-04156443ea9223bb6450b22df11efa1705ab72dab005244a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TAAR8 TMEM255B SHISA3

4.88e-04156443586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 LAMC3 CBFA2T3

4.97e-04157443bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 HHIPL2 OTOG

4.97e-04157443c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 HHIPL2 OTOG

4.97e-041574436b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 HHIPL2 OTOG

4.97e-041574437fdc0094dd5729990a91a30c1982a14c74650b52
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FHL3 ITGB3 SPRING1

5.06e-041584431d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAMC2 COL26A1 SHISA3

5.06e-04158443c8af8964a140acb2987e3b4906d72c546108d229
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RIMS1 FAM221A SHISA8

5.16e-0415944360b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LAMA2 LAMC3 SCARF2

5.16e-04159443cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP4 CDC42BPG RELN

5.25e-041604430bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LAMC2 RIMS1

5.45e-04162443373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

WBP1 RELN SSPOP

5.54e-04163443961c3a1303108afd680365466045f3460a30a7b0
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDC42BPG MEGF11 ZMYM4

5.54e-04163443a24db9d266a40f3bffe4f18d277bc269791b4560
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_DSEL|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMC3 MEGF11 SHISA8

5.64e-041644434a4c32d242db97216cb345e59865c2c826c8b9f2
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN COL26A1 HHIPL2

5.64e-041644437a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN COL26A1 HHIPL2

5.64e-041644435e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN COL26A1 HHIPL2

5.64e-04164443f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCellfacs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC3 ITGB3 FAM221A

5.64e-041644431d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN COL26A1 HHIPL2

5.64e-041644434cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC3 ITGB3 FAM221A

5.64e-04164443bd2e10b015d5e6a338675500ec5d81dc39583b3e
ComputationalAdhesion molecules.

LAMA2 LAMC2 RELN PTK7

9.44e-05141194MODULE_122
DrugAC1L1G72

LAMA2 LAMC2 LAMC3

1.10e-0611443CID000003553
Drug2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine

LAMA2 LAMC2 LAMC3 ITGB3

1.99e-0583444CID011968896
DrugAC1L1B58

LAMA2 LAMC2 LAMC3

2.38e-0529443CID000001288
Diseasescoliosis (implicated_via_orthology)

SSPOP PTK7

1.79e-055402DOID:0060249 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

CNTNAP4 LAMC2 LAMC3 RIMS1

5.35e-05152404DOID:0060041 (implicated_via_orthology)
Diseaseoctadecanedioate measurement

LAMA2 LAMC3

8.01e-0510402EFO_0021056
DiseaseAutism Spectrum Disorders

LAMC3 RELN ITGB3

2.11e-0485403C1510586
Diseaseidiopathic scoliosis (implicated_via_orthology)

SSPOP PTK7

2.12e-0416402DOID:0060250 (implicated_via_orthology)
Diseaselow density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram

RELN RIMS1

4.85e-0424402EFO_0004611, EFO_0006329, EFO_0007871
Diseaselung small cell carcinoma (is_implicated_in)

LAMC2 ATRX

6.62e-0428402DOID:5409 (is_implicated_in)
Diseaseposterior urethral valve

MEGF10 PTK7

7.11e-0429402MONDO_0019640
Diseaselung squamous cell carcinoma (is_marker_for)

LAMC2 ATRX

1.10e-0336402DOID:3907 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
YASCHNSTHCTCEDG

ADGRE4P

21

Q86SQ3
FHCNCTNTGYRGATC

CNTNAP4

571

Q9C0A0
YFGGLASCGAACCTH

SLC25A10

11

Q9UBX3
GLGCDACGYFCHTTC

CDC42BPG

906

Q6DT37
CNCHNGAFCSAYDGE

MEGF10

716

Q96KG7
CFHACSCHNGASCSA

MEGF11

706

A6BM72
FYSNSCCLCCHVRTG

LAPTM4B

101

Q86VI4
LGCSSCYCFGTTTQC

LAMA2

1161

P24043
GCDHNCTDTLTSFYC

LRP2

3121

P98164
TCSGCNAARYCGSFC

CBFA2T3

566

O75081
CSGHGDCISGVCFCD

RELN

1416

P78509
DGCGHLCSYCRTKFC

RIMS1

126

Q86UR5
NNRAYCHYDGGDCCS

PAPPA2

1746

Q9BXP8
GGNLICCDFCHNAFC

ATRX

226

P46100
DCYCSAFSSQCSACG

FHL3

91

Q13643
SCTHCYCLQGQTLCS

CRIM1

836

Q9NZV1
TDRCFHHSECYSGCC

CLPSL2

31

Q6UWE3
ECLCGQCVCHSSDFG

ITGB3

526

P05106
QCFCYGHSASCRSSA

LAMC2

186

Q13753
CCGNFSSHSCEGYLC

KRTAP23-1

6

A1A580
GGNCEDIYSSYHCSC

CRB1

1151

P82279
CNTCSKCSGFHSCFT

FAM221A

141

A4D161
GLCSDYCSAFHSNCH

HHIPL2

131

Q6UWX4
CCCLCGSALATGFLY

COL26A1

11

Q96A83
LGDSCCTSYFCACGD

OTOG

2566

Q6ZRI0
CTSYFCACGDCPDSI

OTOG

2571

Q6ZRI0
GYCDCFASGDFCNNC

TESMIN

306

Q9Y4I5
PNGCCSAYEYCVSCC

SPRING1

121

Q9H741
NCTRCVCHGGAFSCS

SSPOP

4906

A2VEC9
CWYFGAKFCTLHSCC

TAAR8

96

Q969N4
RSNTCYCCDLYACGS

TMEM255B

156

Q8WV15
CCGSCALRYCCAAAD

SHISA3

56

A0PJX4
FNCSTGSYRFCCGTC

SHISA7

96

A6NL88
CSSGAYSFCCGTCGY

SHISA8

76

B8ZZ34
YSFCCGTCGYRFCCH

SHISA8

81

B8ZZ34
SCCYFCGTVCSLIHS

OR5L2

146

Q8NGL0
DCSGHGFCDTGECYC

TNN

236

Q9UQP3
DCAFVCADCGSGHCD

SCARF2

371

Q96GP6
SYFCGISACTSLCNG

SUCO

1176

Q9UBS9
YFTCSSLCLSCGVGC

ZFYVE1

426

Q9HBF4
CGHSYCKGCLVSLSC

TRIM50

31

Q86XT4
GLYSCCAHSAFGQAC

PTK7

196

Q13308
SYICDTGHCCGQSQC

WBP1L

21

Q9NX94
YLCESGHCCGETGCC

WBP1

36

Q96G27
CENCGGYCYSGSGQC

ZMYM4

486

Q5VZL5
GCSSCFCYGHSKVCA

LAMC3

476

Q9Y6N6