Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	5.40e-16	11	134	8	GO:0098973
GeneOntologyMolecularFunction	structural constituent of postsynapse	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	3.06e-11	32	134	8	GO:0099186
GeneOntologyMolecularFunction	structural constituent of synapse	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	3.25e-10	42	134	8	GO:0098918
GeneOntologyMolecularFunction	endopeptidase activity	PRSS1 PRSS2 PRSS8 ADAM19 TMPRSS11F ADAM28 PRSS3P2 TLL2 PRSS21 C1S PAPPA ADAM2 ADAMTS14 CTSE PCSK4 CAPN15	3.23e-08	430	134	16	GO:0004175
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	ANK2 POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	2.34e-07	130	134	9	GO:0005200
GeneOntologyMolecularFunction	metalloendopeptidase activity	PRSS2 ADAM19 ADAM28 TLL2 PAPPA ADAM2 ADAMTS14 CTSE	1.49e-06	120	134	8	GO:0004222
GeneOntologyMolecularFunction	peptidase activity	PRSS1 PRSS2 PRSS8 ADAM19 TMPRSS11F ADAM28 PRSS3P2 SCRN2 TLL2 PRSS21 C1S PAPPA ADAM2 ADAMTS14 CTSE PCSK4 CAPN15	1.86e-06	654	134	17	GO:0008233
GeneOntologyMolecularFunction	serine-type endopeptidase activity	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS3P2 TLL2 PRSS21 C1S PCSK4	5.55e-06	190	134	9	GO:0004252
GeneOntologyMolecularFunction	serine-type peptidase activity	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS3P2 TLL2 PRSS21 C1S PCSK4	1.11e-05	207	134	9	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS3P2 TLL2 PRSS21 C1S PCSK4	1.34e-05	212	134	9	GO:0017171
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	SUCLG2 ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	1.72e-05	48	134	5	GO:0016620
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the aldehyde or oxo group of donors	SUCLG2 ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	3.67e-05	56	134	5	GO:0016903
GeneOntologyMolecularFunction	oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor	GMPR2 GMPR	4.47e-05	2	134	2	GO:0046857
GeneOntologyMolecularFunction	GMP reductase activity	GMPR2 GMPR	4.47e-05	2	134	2	GO:0003920
GeneOntologyMolecularFunction	metallopeptidase activity	PRSS2 ADAM19 ADAM28 TLL2 PAPPA ADAM2 ADAMTS14 CTSE	6.25e-05	200	134	8	GO:0008237
GeneOntologyMolecularFunction	aldehyde dehydrogenase (NAD+) activity	ALDH1L2 ALDH1A3 ALDH7A1	1.27e-04	15	134	3	GO:0004029
GeneOntologyMolecularFunction	aldehyde dehydrogenase [NAD(P)+] activity	ALDH1L2 ALDH1A3 ALDH7A1	1.88e-04	17	134	3	GO:0004030
GeneOntologyMolecularFunction	protein kinase binding	PLK2 ANK2 POTEF ACTB ACTG1 POTEKP POTEE IBTK NBEAL2 PAK2 CDK5RAP2 PRKCH ACTL9 POTEI POTEJ	7.76e-04	873	134	15	GO:0019901
GeneOntologyMolecularFunction	kinase binding	PLK2 ANK2 POTEF POLR2A ACTB ACTG1 POTEKP POTEE IBTK NBEAL2 PAK2 CDK5RAP2 PRKCH ACTL9 POTEI POTEJ	7.89e-04	969	134	16	GO:0019900
GeneOntologyMolecularFunction	structural molecule activity	ANK2 POTEF ACTB EMILIN2 ACTG1 POTEKP CLDN10 BGN POTEE ACTL9 POTEI POTEJ SCARA3 MUC6 NUP160	9.53e-04	891	134	15	GO:0005198
GeneOntologyMolecularFunction	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	MAN1C1 MAN1A2	1.22e-03	8	134	2	GO:0004571
GeneOntologyMolecularFunction	mannosyl-oligosaccharide mannosidase activity	MAN1C1 MAN1A2	1.94e-03	10	134	2	GO:0015924
GeneOntologyBiologicalProcess	postsynaptic actin cytoskeleton organization	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	1.31e-11	31	129	8	GO:0098974
GeneOntologyBiologicalProcess	postsynaptic cytoskeleton organization	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	3.84e-11	35	129	8	GO:0099188
GeneOntologyBiologicalProcess	postsynapse organization	POTEF ACTB ACTG1 POTEKP POTEE NF1 PAK3 PRMT3 ACTL9 POTEI POTEJ	4.48e-06	313	129	11	GO:0099173
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	2.01e-11	32	133	8	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	2.01e-11	32	133	8	GO:0043189
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	3.84e-10	45	133	8	GO:1902562
GeneOntologyCellularComponent	histone acetyltransferase complex	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	1.53e-07	94	133	8	GO:0000123
GeneOntologyCellularComponent	protein acetyltransferase complex	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	3.35e-07	104	133	8	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	4.81e-07	109	133	8	GO:1902493
GeneOntologyCellularComponent	actin filament	POTEF ACTB ACTG1 POTEKP POTEE ACTL9 POTEI POTEJ	4.39e-06	146	133	8	GO:0005884
GeneOntologyCellularComponent	blood microparticle	PRSS1 POTEF ACTB ACTG1 PSMC5 POTEE C1S	3.84e-05	144	133	7	GO:0072562
GeneOntologyCellularComponent	GMP reductase complex	GMPR2 GMPR	4.02e-05	2	133	2	GO:1902560
GeneOntologyCellularComponent	actin cytoskeleton	ACTRT3 POTEF SH3GL1 ACTB ACTG1 POTEKP CDC42BPB POTEE ACTL9 POTEI POTEJ MTSS2	3.18e-04	576	133	12	GO:0015629
GeneOntologyCellularComponent	dense body	ACTB ACTG1	8.26e-04	7	133	2	GO:0097433
Domain	Actin/actin-like_CS	ACTRT3 POTEF ACTB ACTG1 POTEE POTEI POTEJ	1.52e-11	18	125	7	IPR020902
Domain	Actin	ACTRT3 POTEF ACTB ACTG1 POTEE ACTL9 POTEI POTEJ	2.23e-11	31	125	8	IPR004000
Domain	Actin	ACTRT3 POTEF ACTB ACTG1 POTEE ACTL9 POTEI POTEJ	2.23e-11	31	125	8	PF00022
Domain	ACTIN	ACTRT3 POTEF ACTB ACTG1 POTEE ACTL9 POTEI POTEJ	2.23e-11	31	125	8	SM00268
Domain	ACTINS_ACT_LIKE	ACTRT3 POTEF ACTB ACTG1 POTEE POTEI POTEJ	2.39e-11	19	125	7	PS01132
Domain	Actin_CS	POTEF ACTB ACTG1 POTEE POTEI POTEJ	6.04e-10	16	125	6	IPR004001
Domain	ACTINS_2	POTEF ACTB ACTG1 POTEE POTEI POTEJ	9.28e-10	17	125	6	PS00432
Domain	Ald_DH_CS_CYS	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	4.25e-06	17	125	4	IPR016160
Domain	ALDEHYDE_DEHYDR_CYS	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	5.44e-06	18	125	4	PS00070
Domain	ALDEHYDE_DEHYDR_GLU	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	5.44e-06	18	125	4	PS00687
Domain	-	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	6.86e-06	19	125	4	3.40.605.10
Domain	Aldedh	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	6.86e-06	19	125	4	PF00171
Domain	Ald_DH_C	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	6.86e-06	19	125	4	IPR016163
Domain	Ald_DH_N	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	6.86e-06	19	125	4	IPR016162
Domain	Ald_DH/histidinol_DH	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	6.86e-06	19	125	4	IPR016161
Domain	Aldehyde_DH_dom	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	6.86e-06	19	125	4	IPR015590
Domain	-	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	6.86e-06	19	125	4	3.40.309.10
Domain	-	ADAM19 ADAM28 TLL2 PAPPA ADAM2 ADAMTS14	1.72e-05	81	125	6	3.40.390.10
Domain	MetalloPept_cat_dom	ADAM19 ADAM28 TLL2 PAPPA ADAM2 ADAMTS14	1.72e-05	81	125	6	IPR024079
Domain	ADAM_Cys-rich	ADAM19 ADAM28 ADAM2 ADAMTS14	2.98e-05	27	125	4	IPR006586
Domain	ACR	ADAM19 ADAM28 ADAM2 ADAMTS14	2.98e-05	27	125	4	SM00608
Domain	TRYPSIN_SER	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS21 C1S	3.13e-05	90	125	6	IPR033116
Domain	GMPR	GMPR2 GMPR	4.44e-05	2	125	2	IPR005993
Domain	-	CDC42BPB PAK2 PAK3	6.16e-05	12	125	3	3.90.810.10
Domain	TRYPSIN_HIS	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS21 C1S	6.70e-05	103	125	6	IPR018114
Domain	TRYPSIN_SER	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS21 C1S	7.87e-05	106	125	6	PS00135
Domain	TRYPSIN_HIS	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS21 C1S	8.29e-05	107	125	6	PS00134
Domain	Peptidase_S1A	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS21 C1S	1.12e-04	113	125	6	IPR001314
Domain	TRYPSIN_DOM	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS21 C1S	1.24e-04	115	125	6	PS50240
Domain	Pep_M12B_propep	ADAM19 ADAM28 ADAM2 ADAMTS14	1.31e-04	39	125	4	PF01562
Domain	Peptidase_M12B_N	ADAM19 ADAM28 ADAM2 ADAMTS14	1.31e-04	39	125	4	IPR002870
Domain	Tryp_SPc	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS21 C1S	1.36e-04	117	125	6	SM00020
Domain	DISINTEGRIN_1	ADAM19 ADAM28 ADAM2 ADAMTS14	1.45e-04	40	125	4	PS00427
Domain	Reprolysin	ADAM19 ADAM28 ADAM2 ADAMTS14	1.45e-04	40	125	4	PF01421
Domain	ADAM_MEPRO	ADAM19 ADAM28 ADAM2 ADAMTS14	1.45e-04	40	125	4	PS50215
Domain	DISINTEGRIN_2	ADAM19 ADAM28 ADAM2 ADAMTS14	1.45e-04	40	125	4	PS50214
Domain	Peptidase_M12B	ADAM19 ADAM28 ADAM2 ADAMTS14	1.45e-04	40	125	4	IPR001590
Domain	Disintegrin_CS	ADAM19 ADAM28 ADAM2	1.54e-04	16	125	3	IPR018358
Domain	Ald_DH_CS_GLU	ALDH1L2 ALDH1A3 ALDH7A1	1.54e-04	16	125	3	IPR029510
Domain	PBD	CDC42BPB PAK2 PAK3	1.54e-04	16	125	3	SM00285
Domain	Disintegrin_dom	ADAM19 ADAM28 ADAM2 ADAMTS14	1.60e-04	41	125	4	IPR001762
Domain	Trypsin_dom	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS21 C1S	1.63e-04	121	125	6	IPR001254
Domain	Trypsin	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS21 C1S	1.63e-04	121	125	6	PF00089
Domain	Peptidase_S1_PA	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS21 C1S	1.79e-04	123	125	6	IPR009003
Domain	PBD	CDC42BPB PAK2 PAK3	1.86e-04	17	125	3	PF00786
Domain	ADAM_CR	ADAM19 ADAM28 ADAM2	2.22e-04	18	125	3	PF08516
Domain	LamGL	PAPPA USH2A	2.64e-04	4	125	2	SM00560
Domain	IMPDH	GMPR2 GMPR	2.64e-04	4	125	2	PF00478
Domain	IMP_DH_GMPRt	GMPR2 GMPR	2.64e-04	4	125	2	IPR001093
Domain	LamG-like	PAPPA USH2A	2.64e-04	4	125	2	IPR006558
Domain	IMP_DH_GMP_RED	GMPR2 GMPR	2.64e-04	4	125	2	PS00487
Domain	IMP_DH/GMP_Rdtase_CS	GMPR2 GMPR	2.64e-04	4	125	2	IPR015875
Domain	CRIB	CDC42BPB PAK2 PAK3	3.07e-04	20	125	3	PS50108
Domain	-	ADAM19 ADAM28 ADAM2	3.07e-04	20	125	3	4.10.70.10
Domain	EGF_1	ADAM19 FAT3 ADAM28 CELSR2 TLL2 C1S ADAM2 USH2A	3.22e-04	255	125	8	PS00022
Domain	Disintegrin	ADAM19 ADAM28 ADAM2	3.56e-04	21	125	3	PF00200
Domain	CRIB_dom	CDC42BPB PAK2 PAK3	3.56e-04	21	125	3	IPR000095
Domain	DISIN	ADAM19 ADAM28 ADAM2	3.56e-04	21	125	3	SM00050
Domain	YTH	YTHDF2 YTHDF3	4.39e-04	5	125	2	PF04146
Domain	YTH_domain	YTHDF2 YTHDF3	4.39e-04	5	125	2	IPR007275
Domain	YTH	YTHDF2 YTHDF3	4.39e-04	5	125	2	PS50882
Domain	ZINC_PROTEASE	ADAM19 ADAM28 TLL2 PAPPA ADAMTS14	5.12e-04	98	125	5	PS00142
Domain	Ank_2	ANK2 POTEF POTEE IBTK ANKRD11 POTEI POTEJ	6.15e-04	215	125	7	PF12796
Domain	PAK_BD	PAK2 PAK3	6.55e-04	6	125	2	IPR033923
Domain	Ank	ANK2 POTEF POTEE IBTK ANKRD11 POTEI POTEJ	8.69e-04	228	125	7	PF00023
Domain	Glyco_hydro_47	MAN1C1 MAN1A2	9.13e-04	7	125	2	PF01532
Domain	-	MAN1C1 MAN1A2	9.13e-04	7	125	2	1.50.10.50
Domain	EGF_3	ADAM19 FAT3 ADAM28 CELSR2 TLL2 C1S ADAM2	1.04e-03	235	125	7	PS50026
Domain	ACTINS_1	ACTB ACTG1	1.21e-03	8	125	2	PS00406
Domain	Glyco_hydro_47	MAN1C1 MAN1A2	1.21e-03	8	125	2	IPR001382
Domain	-	ANK2 POTEF POTEE IBTK ANKRD11 POTEI POTEJ	1.41e-03	248	125	7	1.25.40.20
Domain	EGF-like_dom	ADAM19 FAT3 ADAM28 FCGBP CELSR2 TLL2 C1S	1.45e-03	249	125	7	IPR000742
Domain	ANK	ANK2 POTEF POTEE IBTK ANKRD11 POTEI POTEJ	1.51e-03	251	125	7	SM00248
Domain	ANK_REPEAT	ANK2 POTEF POTEE IBTK ANKRD11 POTEI POTEJ	1.58e-03	253	125	7	PS50088
Domain	Ankyrin_rpt-contain_dom	ANK2 POTEF POTEE IBTK ANKRD11 POTEI POTEJ	1.62e-03	254	125	7	IPR020683
Domain	ANK_REP_REGION	ANK2 POTEF POTEE IBTK ANKRD11 POTEI POTEJ	1.62e-03	254	125	7	PS50297
Domain	Ankyrin_rpt	ANK2 POTEF POTEE IBTK ANKRD11 POTEI POTEJ	1.93e-03	262	125	7	IPR002110
Domain	EGF_2	ADAM19 FAT3 ADAM28 CELSR2 TLL2 C1S ADAM2	2.06e-03	265	125	7	PS01186
Domain	LAM_G_DOMAIN	FAT3 CELSR2 USH2A	2.08e-03	38	125	3	PS50025
Domain	Laminin_G_2	FAT3 CELSR2 USH2A	2.41e-03	40	125	3	PF02210
Domain	CYSTEINE_SWITCH	ADAM19 ADAM28 ADAMTS14	2.59e-03	41	125	3	PS00546
Domain	Pkinase_C	CDC42BPB PRKCH MAST3	2.78e-03	42	125	3	PF00433
Domain	-	GMPR2 GMPR PC	2.78e-03	42	125	3	3.20.20.70
Domain	C8	FCGBP MUC6	2.81e-03	12	125	2	PF08742
Domain	TIL	FCGBP MUC6	2.81e-03	12	125	2	PF01826
Domain	Pept_M10_metallopeptidase	ADAM19 ADAM28 ADAMTS14	2.97e-03	43	125	3	IPR001818
Domain	Aldolase_TIM	GMPR2 GMPR PC	3.17e-03	44	125	3	IPR013785
Domain	LamG	FAT3 CELSR2 USH2A	3.17e-03	44	125	3	SM00282
Domain	Unchr_dom_Cys-rich	FCGBP MUC6	3.30e-03	13	125	2	IPR014853
Domain	C8	FCGBP MUC6	3.30e-03	13	125	2	SM00832
Domain	-	FAT3 CELSR2 PAPPA USH2A	3.81e-03	95	125	4	2.60.120.200
Domain	TIL_dom	FCGBP MUC6	3.84e-03	14	125	2	IPR002919
Domain	ATP_GRASP	SUCLG2 PC	3.84e-03	14	125	2	PS50975
Domain	ATP-grasp	SUCLG2 PC	3.84e-03	14	125	2	IPR011761
Domain	-	SUCLG2 PC	4.41e-03	15	125	2	3.30.1490.20
Domain	VWF_type-D	FCGBP MUC6	5.01e-03	16	125	2	IPR001846
Domain	VWFD	FCGBP MUC6	5.01e-03	16	125	2	PS51233
Domain	VWD	FCGBP MUC6	5.01e-03	16	125	2	SM00216
Domain	VWD	FCGBP MUC6	5.01e-03	16	125	2	PF00094
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT3 CELSR2 TLL2 C1S	5.62e-03	106	125	4	IPR000152
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	PRSS1 PRSS2 ADAM19 EMILIN2 ITGA10 P4HA3 BGN TLL2 ADAMTS14 CAPN15	1.00e-05	258	96	10	MM14572
Pathway	WP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS	LIMD1 ACTB ACTG1 PAK2 PAK3	1.61e-05	47	96	5	M39829
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	PRSS1 PRSS2 ADAM19 EMILIN2 ITGA10 P4HA3 BGN TLL2 ADAMTS14 CAPN15	3.68e-05	300	96	10	M610
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEF ACTB ACTG1 POTEKP POTEE POTEI POTEJ	7.11e-14	15	135	7	16824795
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	NIBAN1 PRSS8 GALNS MAN1C1 POTEF ACTB ACTG1 POTEKP GALNT7 BGN POTEE FCGBP IGF2R ALDH1L2 SCARB2 CPNE4 POTEI POTEJ ALDH1A3 ALDH7A1	6.45e-09	1070	135	20	23533145
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTEKP POTEE POTEI POTEJ	2.69e-08	9	135	4	16364570
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	PRSS2 PLK2 ADAM19 POLR2A MTMR8 KMT2E CDC42BPB DGKK PRSS21 UBA6 PAK2 KCNS2 PRKCH ADAM2 PRMT3 PCSK4	2.75e-08	730	135	16	34857952
Pubmed	Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.	PRSS1 PRSS2 PRSS3P2	5.72e-08	3	135	3	11073713
Pubmed	The origin of trypsin: evidence for multiple gene duplications in trypsins.	PRSS1 PRSS2 PRSS3P2	5.72e-08	3	135	3	9732462
Pubmed	Evolution and expression of chimeric POTE-actin genes in the human genome.	POTEF POTEE POTEJ	5.72e-08	3	135	3	17101985
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	ANK2 POTEF ACTB ACTG1 POTEKP POTEE CEBPZ POTEI POTEJ TOP2B	1.17e-07	271	135	10	32433965
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	PRSS1 POTEF POLR2A ACTB ACTG1 POTEKP CDC42BPB POTEJ	1.33e-06	202	135	8	24639526
Pubmed	Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.	PRSS1 POTEF ACTB ACTG1 PSMC5 POTEE C1S	1.53e-06	143	135	7	22516433
Pubmed	Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems.	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	1.82e-06	23	135	4	18971422
Pubmed	Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.	POTEF ACTB ACTG1 POTEE POTEI POTEJ	2.13e-06	96	135	6	23580065
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	GALNS MAZ ACTB ACTG1 PSMC5 GALNT7 CDC42BPB GMPS IGF2R FAM120A SCARB2 PRSS21 BRAT1 SCARA3 NUP160 YTHDF2 YTHDF3 ALDH7A1	2.96e-06	1297	135	18	33545068
Pubmed	Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.	ACTB ACTG1 PAK2	3.16e-06	8	135	3	20147394
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	MTA2 NIBAN1 DCAF8 LIMD1 POLR2A SH3GL1 ACTG1 RANBP6 PSMC5 GMPR2 TXNRD1 GMPS UBA6 PAK2 PRMT3 BRAT1 NUP160 YTHDF2 ALDH7A1	3.70e-06	1455	135	19	22863883
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	PLK2 LIMD1 MAZ ACTB ZNF629 PSMC5 FASTKD5 KMT2E GALNT7 MAN1A2 IGF2R CEBPZ SLC27A1 SCARB2 BRAT1 NUP160 TOP2B	4.50e-06	1203	135	17	29180619
Pubmed	Defining the membrane proteome of NK cells.	MTA2 NIBAN1 ATP13A1 ACTB ACTG1 PSMC5 IRF4 GALNT7 MAN1A2 IGF2R NF1 FAM120A NBEAL2 SLC27A1 SCARB2 BRAT1	1.29e-05	1168	135	16	19946888
Pubmed	Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity.	ACTB ACTG1	1.50e-05	2	135	2	19638415
Pubmed	Beta- and gamma-cytoplasmic actins are required for meiosis in mouse oocytes.	ACTB ACTG1	1.50e-05	2	135	2	21778137
Pubmed	De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome.	ACTB ACTG1	1.50e-05	2	135	2	22366783
Pubmed	Botulinum C2 toxin ADP-ribosylates cytoplasmic beta/gamma-actin in arginine 177.	ACTB ACTG1	1.50e-05	2	135	2	3335520
Pubmed	Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization.	ACTB ACTG1	1.50e-05	2	135	2	9288906
Pubmed	High level expression of transfected beta- and gamma-actin genes differentially impacts on myoblast cytoarchitecture.	ACTB ACTG1	1.50e-05	2	135	2	1577857
Pubmed	Prenatal presentation and diagnosis of Baraitser-Winter syndrome using exome sequencing.	ACTB ACTG1	1.50e-05	2	135	2	32588558
Pubmed	Gene conversion between cationic trypsinogen (PRSS1) and the pseudogene trypsinogen 6 (PRSS3P2) in patients with chronic pancreatitis.	PRSS1 PRSS3P2	1.50e-05	2	135	2	25546417
Pubmed	Baraitser-Winter cerebrofrontofacial syndrome.	ACTB ACTG1	1.50e-05	2	135	2	27625340
Pubmed	Molecular pathology and evolutionary and physiological implications of pancreatitis-associated cationic trypsinogen mutations.	PRSS1 PRSS3P2	1.50e-05	2	135	2	11702203
Pubmed	Baraitser-Winter Cerebrofrontofacial Syndrome	ACTB ACTG1	1.50e-05	2	135	2	26583190
Pubmed	Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) Technique Shows that Non-Muscle β and γ Actin Are Not Equal in Relation to Human Melanoma Cells' Motility and Focal Adhesion Formation.	ACTB ACTG1	1.50e-05	2	135	2	32326615
Pubmed	Severe forms of Baraitser-Winter syndrome are caused by ACTB mutations rather than ACTG1 mutations.	ACTB ACTG1	1.50e-05	2	135	2	23756437
Pubmed	Alcohol Consumption and Cigarette Smoking are Important Modifiers of the Association Between Acute Pancreatitis and the PRSS1-PRSS2 Locus in Men.	PRSS1 PRSS2	1.50e-05	2	135	2	27846138
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEF POTEE	1.50e-05	2	135	2	19669888
Pubmed	YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.	YTHDF2 YTHDF3	1.50e-05	2	135	2	32905781
Pubmed	Cytochalasin D-induced actin gene expression in murine erythroleukemia cells.	ACTB ACTG1	1.50e-05	2	135	2	8482333
Pubmed	Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells.	POTEE POTEJ	1.50e-05	2	135	2	18447647
Pubmed	Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).	PRSS1 PRSS2	1.50e-05	2	135	2	14695529
Pubmed	Identification and mapping of human cDNAs homologous to Drosophila mutant genes through EST database searching.	KCNS2 CAPN15	1.50e-05	2	135	2	8640222
Pubmed	Isolation of cDNA clones for mouse cytoskeletal gamma-actin and differential expression of cytoskeletal actin mRNAs in mouse cells.	ACTB ACTG1	1.50e-05	2	135	2	3221869
Pubmed	Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl.	PRSS1 PRSS2	1.50e-05	2	135	2	15776435
Pubmed	Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms.	ACTB ACTG1	1.50e-05	2	135	2	29265728
Pubmed	Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia.	ACTB ACTG1	1.50e-05	2	135	2	22246323
Pubmed	Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression.	PRSS1 PRSS2	1.50e-05	2	135	2	36191639
Pubmed	Prostasin may contribute to chemoresistance, repress cancer cells in ovarian cancer, and is involved in the signaling pathways of CASP/PAK2-p34/actin.	PRSS8 PAK2	1.50e-05	2	135	2	24434518
Pubmed	Reaction mechanism and specificity of human GMP reductase. Substrates, inhibitors, activators, and inactivators.	GMPR2 GMPR	1.50e-05	2	135	2	218932
Pubmed	Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes.	ACTB ACTG1	1.50e-05	2	135	2	2837653
Pubmed	Prevalence of Cytoplasmic Actin Mutations in Diffuse Large B-Cell Lymphoma and Multiple Myeloma: A Functional Assessment Based on Actin Three-Dimensional Structures.	ACTB ACTG1	1.50e-05	2	135	2	32349449
Pubmed	Baraitser-Winter cerebrofrontofacial syndrome: Report of two adult siblings.	ACTB ACTG1	1.50e-05	2	135	2	32506774
Pubmed	Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation.	PRSS1 PRSS2	1.50e-05	2	135	2	18461367
Pubmed	Role of the Common PRSS1-PRSS2 Haplotype in Alcoholic and Non-Alcoholic Chronic Pancreatitis: Meta- and Re-Analyses.	PRSS1 PRSS2	1.50e-05	2	135	2	33202925
Pubmed	Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer.	PRSS1 PRSS2	1.50e-05	2	135	2	15651064
Pubmed	Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation.	ACTB ACTG1	1.50e-05	2	135	2	20847274
Pubmed	Spatial organization of RNA polymerase II transcription in the nucleus.	POLR2A ACTB	1.50e-05	2	135	2	10773068
Pubmed	Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension.	ACTB ACTG1	1.50e-05	2	135	2	21502360
Pubmed	The evolution and complexity of the genes encoding the cytoskeletal proteins of human epidermal cells.	ACTB ACTG1	1.50e-05	2	135	2	6686106
Pubmed	Actin amino-acid sequences. Comparison of actins from calf thymus, bovine brain, and SV40-transformed mouse 3T3 cells with rabbit skeletal muscle actin.	ACTB ACTG1	1.50e-05	2	135	2	213279
Pubmed	The First Korean Case of Baraitser-Winter Cerebro-Fronto-Facial Syndrome with a Novel Mutation in ACTB Diagnosed Via Targeted Gene Panel Sequencing and Literature Review.	ACTB ACTG1	1.50e-05	2	135	2	33334799
Pubmed	β-Actin specifically controls cell growth, migration, and the G-actin pool.	ACTB ACTG1	1.50e-05	2	135	2	21900491
Pubmed	Immunoreactive anionic and cationic trypsin in human serum.	PRSS1 PRSS2	1.50e-05	2	135	2	2598466
Pubmed	Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.	PRSS1 PRSS2	1.50e-05	2	135	2	20484960
Pubmed	Actin co-purifies with RNA polymerase II.	POLR2A ACTB	1.50e-05	2	135	2	435297
Pubmed	Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis.	PRSS1 PRSS2	1.50e-05	2	135	2	35089416
Pubmed	NADPH-dependent GMP reductase isoenzyme of human (GMPR2). Expression, purification, and kinetic properties.	GMPR2 GMPR	1.50e-05	2	135	2	12009299
Pubmed	Trypsinogen copy number mutations in patients with idiopathic chronic pancreatitis.	PRSS1 PRSS2	1.50e-05	2	135	2	18063422
Pubmed	PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway.	CDC42BPB PAK2 PAK3	2.02e-05	14	135	3	18586681
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	POLR2A GALNT7 GMPS IGF2R SCARB2 SLC35F6 PC NUP160 YTHDF2	2.40e-05	392	135	9	33144569
Pubmed	Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.	POTEF ACTB POTEE KATNIP POTEI POTEJ	2.67e-05	149	135	6	22664934
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	LIMD1 MAZ SH3GL1 ZNF629 CDC42BPB IBTK FAM120A CEBPZ PAK2 YTHDF2 TOP2B YTHDF3	2.72e-05	724	135	12	36232890
Pubmed	Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.	PRSS1 PRSS2	4.48e-05	3	135	2	24146905
Pubmed	Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein.	ACTB ACTG1	4.48e-05	3	135	2	9245787
Pubmed	Prognostic significance of PAK family kinases in acute myeloid leukemia.	PAK2 PAK3	4.48e-05	3	135	2	30890765
Pubmed	YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.	YTHDF2 YTHDF3	4.48e-05	3	135	2	28106072
Pubmed	Characterization of a cDNA encoding a novel human Golgi alpha 1, 2-mannosidase (IC) involved in N-glycan biosynthesis.	MAN1C1 MAN1A2	4.48e-05	3	135	2	10915796
Pubmed	Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation.	PAK2 PAK3	4.48e-05	3	135	2	10075701
Pubmed	YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation.	YTHDF2 YTHDF3	4.48e-05	3	135	2	35508130
Pubmed	Impact of altered actin gene expression on vinculin, talin, cell spreading, and motility.	ACTB ACTG1	4.48e-05	3	135	2	7646816
Pubmed	Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice.	PAK2 PAK3	4.48e-05	3	135	2	15182717
Pubmed	The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.	PAK2 PAK3	4.48e-05	3	135	2	23335370
Pubmed	Group I Paks as therapeutic targets in NF2-deficient meningioma.	PAK2 PAK3	4.48e-05	3	135	2	25596744
Pubmed	Trypsin-mediated enzymatic degradation of type II collagen in the human vitreous.	PRSS1 PRSS2	4.48e-05	3	135	2	23882137
Pubmed	YTH: a new domain in nuclear proteins.	YTHDF2 YTHDF3	4.48e-05	3	135	2	12368078
Pubmed	Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL.	ACTB ACTG1	4.48e-05	3	135	2	19008859
Pubmed	Angiostatin and plasminogen share binding to endothelial cell surface actin.	ACTB ACTG1	4.48e-05	3	135	2	15746964
Pubmed	Interaction of Receptor-Binding Domain of the SARS-CoV-2 Omicron Variant with hACE2 and Actin.	ACTB ACTG1	4.48e-05	3	135	2	39195208
Pubmed	A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA.	YTHDF2 YTHDF3	4.48e-05	3	135	2	32492408
Pubmed	Actin Is Crucial for All Kinetically Distinguishable Forms of Endocytosis at Synapses.	ACTB ACTG1	4.48e-05	3	135	2	27840001
Pubmed	Restricted morphological and behavioral abnormalities following ablation of β-actin in the brain.	ACTB ACTG1	4.48e-05	3	135	2	22403730
Pubmed	Functional molecular complexes of human N-formyl chemoattractant receptors and actin.	ACTB ACTG1	4.48e-05	3	135	2	8228254
Pubmed	YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation.	PRSS8 YTHDF2	4.48e-05	3	135	2	38462165
Pubmed	The four mammalian splice variants encoded by the p21-activated kinase 3 gene have different biological properties.	PAK2 PAK3	4.48e-05	3	135	2	18507705
Pubmed	m6A enhances the phase separation potential of mRNA.	YTHDF2 YTHDF3	4.48e-05	3	135	2	31292544
Pubmed	Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq.	YTHDF2 YTHDF3	4.48e-05	3	135	2	22575960
Pubmed	CTGF/Hcs24 interacts with the cytoskeletal protein actin in chondrocytes.	ACTB ACTG1	4.48e-05	3	135	2	12470643
Pubmed	Comprehensive Analysis of YTH Domain Family in Lung Adenocarcinoma: Expression Profile, Association with Prognostic Value, and Immune Infiltration.	YTHDF2 YTHDF3	4.48e-05	3	135	2	34497675
Pubmed	m6A modification controls the innate immune response to infection by targeting type I interferons.	YTHDF2 YTHDF3	4.48e-05	3	135	2	30559377
Pubmed	Association of claudin2 and PRSS1-PRSS2 polymorphisms with idiopathic recurrent acute and chronic pancreatitis: A case-control study from India.	PRSS1 PRSS2	4.48e-05	3	135	2	26110235
Pubmed	RNA helicase A acts as a bridging factor linking nuclear beta-actin with RNA polymerase II.	POLR2A ACTB	4.48e-05	3	135	2	19309309
Pubmed	Porocarcinomas with PAK1/2/3 fusions: a series of 12 cases.	PAK2 PAK3	4.48e-05	3	135	2	38785043
Pubmed	Divergent roles of SPINK1 and PRSS2 variants in tropical calcific pancreatitis.	PRSS1 PRSS2	4.48e-05	3	135	2	19077465
Pubmed	Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.	ACTB ACTG1	4.48e-05	3	135	2	6865942
Pubmed	CD4-binding regions of human immunodeficiency virus envelope glycoprotein gp120 defined by proteolytic digestion.	PRSS1 PRSS2	4.48e-05	3	135	2	1763044
Interaction	ACTG2 interactions	POTEF ACTB ACTG1 POTEE POTEI POTEJ	8.17e-07	49	133	6	int:ACTG2
Interaction	B9D2 interactions	P4HA3 IBTK PWP2 NUP160 YTHDF2 YTHDF3	8.74e-06	73	133	6	int:B9D2
Interaction	POTEJ interactions	ACTB ACTG1 POTEE POTEI POTEJ	2.35e-05	52	133	5	int:POTEJ
Cytoband	2q21.1	POTEF POTEKP POTEE POTEI POTEJ	8.25e-07	58	135	5	2q21.1
Cytoband	19p13.11	CPAMD8 ATP13A1 SLC27A1 MAST3	6.65e-05	73	135	4	19p13.11
Cytoband	Ensembl 112 genes in cytogenetic band chr2q21	POTEF POTEKP POTEE POTEI POTEJ	8.85e-05	151	135	5	chr2q21
Cytoband	16p11.2	PRSS8 FBXL19-AS1 MAZ ZNF629 RRN3P2	2.65e-04	191	135	5	16p11.2
Cytoband	1p35	MAN1C1 YTHDF2	6.55e-04	13	135	2	1p35
Cytoband	Ensembl 112 genes in cytogenetic band chr16p11	PRSS8 FBXL19-AS1 MAZ ZNF629 RRN3P2	1.44e-03	278	135	5	chr16p11
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEF POTEKP POTEE POTEI POTEJ	4.73e-09	13	96	5	685
GeneFamily	Aldehyde dehydrogenases	ALDH1L2 ALDH1A3 ALDH6A1 ALDH7A1	2.72e-06	19	96	4	398
GeneFamily	Proteases, serine	PRSS1 PRSS2 PRSS8 TMPRSS11F PRSS21	2.09e-05	63	96	5	738
GeneFamily	Mannosidases alpha class 1	MAN1C1 MAN1A2	1.66e-04	4	96	2	1193
GeneFamily	Ankyrin repeat domain containing	ANK2 POTEF POTEE IBTK ANKRD11 POTEI POTEJ	3.06e-04	242	96	7	403
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM19 ADAM28 ADAM2	3.87e-04	27	96	3	47
GeneFamily	Actins	ACTB ACTG1	4.13e-04	6	96	2	929
Coexpression	NABA_ECM_REGULATORS	PRSS1 PRSS2 CPAMD8 ADAM19 P4HA3 ADAM28 TLL2 PAPPA ADAM2 ADAMTS14 CTSE	4.23e-08	238	134	11	M3468
Coexpression	NABA_ECM_REGULATORS	PRSS1 PRSS2 ADAM19 P4HA3 ADAM28 TLL2 PAPPA ADAM2 ADAMTS14 CTSE	5.01e-07	242	134	10	MM17062
Coexpression	GRYDER_PAX3FOXO1_TOP_ENHANCERS	ADAM19 MAN1C1 ACTB ACTG1 TXNRD1 MAN1A2 CEBPZ GMPR ADAMTS14 ALDH1A3 NUP160	1.74e-05	441	134	11	M172
Coexpression	NABA_MATRISOME	PRSS1 PRSS2 CPAMD8 ADAM19 EMILIN2 P4HA3 ADAM28 BGN TLL2 ANXA10 PAPPA ADAM2 C1QTNF6 ADAMTS14 CTSE USH2A MUC6	1.98e-05	1026	134	17	M5889
Coexpression	NABA_MATRISOME_ASSOCIATED	PRSS1 PRSS2 CPAMD8 ADAM19 P4HA3 ADAM28 TLL2 ANXA10 PAPPA ADAM2 C1QTNF6 ADAMTS14 CTSE MUC6	3.19e-05	751	134	14	M5885
Coexpression	KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN	POLR2A ZNF629 CLDN10 TXNRD1 IGF2R FAM120A ALDH6A1	4.97e-05	186	134	7	M1993
Coexpression	GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_DN	PSMC5 KATNBL1 MAN1A2 PWP2 PRMT3 PC NUP160	7.61e-05	199	134	7	M4025
Coexpression	SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN	PLK2 ACADSB GALNT7 CELSR2 CADPS2	7.66e-05	85	134	5	M7012
Coexpression	GSE13522_WT_VS_IFNAR_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP	NIBAN1 ADAM19 ETFBKMT IRF4 IGF2R PRKCH CTSE	7.86e-05	200	134	7	M2933
Coexpression	GSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_DN	IRF4 ARMCX4 IBTK SLC35F6 ALDH6A1 MAST3 CAPN15	7.86e-05	200	134	7	M7801
Coexpression	GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_DN	LIMD1 FASTKD5 IRF4 GMPR2 IGF2R NBEAL2 MAST3	7.86e-05	200	134	7	M6896
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIF26A CELSR2 PAK3 KCNS2 POTEI POTEJ USH2A PCSK4 UNC80	8.58e-09	196	134	9	4bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-4\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ANK2 P4HA3 BGN ALDH1L2 C1S PAPPA ALDH1A3 SCARA3	1.71e-07	200	134	8	7642a14855589b0b3f68dbdc9e4d3fc7291854f7
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-4-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ANK2 P4HA3 BGN ALDH1L2 C1S PAPPA ALDH1A3 SCARA3	1.71e-07	200	134	8	444c72334df421375ae6fc69b0adfd4950d49a43
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-4\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ANK2 P4HA3 BGN ALDH1L2 C1S PAPPA ALDH1A3 SCARA3	1.71e-07	200	134	8	5826c17da67bdaba3a828792279004218d8260c8
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	PRSS1 PRSS2 ANXA10 SLC25A29 ALDH1A3 CTSE MUC6	9.21e-07	172	134	7	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC13A3 CLDN10 SCRN2 CPNE4 PC DDX4 CAPN15	1.39e-06	183	134	7	85446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIF26A FAT3 KCNS2 POTEI POTEJ PCSK4 UNC80	2.06e-06	194	134	7	2dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ANK2 FAT3 ITGA10 SUCLG2 BGN C1S MTSS2	2.28e-06	197	134	7	d7cef7881abd807a679432766ced609a6efd1067
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ANK2 FAT3 ITGA10 SUCLG2 BGN C1S MTSS2	2.28e-06	197	134	7	20a5958512bdb99daeb8f4d244df53e4f048f879
ToppCell	proximal-Epithelial-Mucous-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRSS1 PLK2 GALNT7 CLDN10 ADAM28 FCGBP ALDH1A3	2.43e-06	199	134	7	baac580484124b7c36717b607adcf2cb446e631d
ToppCell	proximal-Epithelial-Mucous\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRSS1 PLK2 GALNT7 CLDN10 ADAM28 FCGBP ALDH1A3	2.43e-06	199	134	7	15ba36fa6ad73d0e959e42f18d7acbc14e310dc9
ToppCell	proximal-3-Epithelial-Mucous\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRSS1 PLK2 GALNT7 CLDN10 ADAM28 FCGBP ALDH1A3	2.43e-06	199	134	7	3018378860de084662be0cc46fce421db3bb9ec9
ToppCell	Biopsy_Other_PF-Epithelial-KRT5-/KRT17+\|Biopsy_Other_PF / Sample group, Lineage and Cell type	PRSS1 PRSS2 PRSS8 KIF26B PAPPA ALDH1A3 CTSE	2.52e-06	200	134	7	077e6b9340686de9d0f11b035a8954e1f6a1b790
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NIBAN1 PRSS8 GALNT7 CLDN10 ADAM28 FCGBP ALDH1A3	2.52e-06	200	134	7	133853d0f55c63ebe94dd54151f9f1f90650a0d8
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ANK2 P4HA3 BGN ALDH1L2 C1S PAPPA ALDH1A3	2.52e-06	200	134	7	54806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 MTMR8 KCNS2 PAPPA SLC25A29 CADPS2	5.59e-06	147	134	6	64fa0753a3a79f492ef8acc6942bf90d379a983f
ToppCell	367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NIBAN1 PLK2 RNF112 ADAM28 CPNE4 MUC6	7.57e-06	155	134	6	8dab23aad905cc35a35643baa0554acb3f6fe6c8
ToppCell	367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NIBAN1 PLK2 RNF112 ADAM28 CPNE4 MUC6	7.57e-06	155	134	6	42533beaded07068f00540de704de07e4f19abcf
ToppCell	TCGA-Pancreas\|World / Sample_Type by Project: Shred V9	PRSS1 PRSS2 ADAM28 ANXA10 CTSE MUC6	1.20e-05	168	134	6	279d5fcf9bd3f56ab560e37eed6fb3bd57dd93de
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS1 PRSS2 CLDN10 ANXA10 CTSE MUC6	1.24e-05	169	134	6	a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF112 ADAM28 KCNS2 C1S PAPPA ADAMTS14	1.24e-05	169	134	6	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 POLR2A PKHD1L1 ADAM28 USH2A UNC80	1.24e-05	169	134	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 PRSS8 FAT3 CLDN10 SLC6A9 SCARA3	1.51e-05	175	134	6	3f1b2e23fec953148fb0711e523c463adb07dca4
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 P4HA3 CLDN10 CELSR2 UBA6 SCARA3	1.56e-05	176	134	6	5e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FAT3 ITGA10 BGN PAPPA CADPS2 SCARA3	1.66e-05	178	134	6	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	facs-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 PRSS8 FAT3 CLDN10 SLC6A9 SCARA3	1.72e-05	179	134	6	bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega\|lymph-node_spleen / Manually curated celltypes from each tissue	SLC6A9 GMPR C1QTNF6 PCSK4 ALDH7A1 MTSS2	1.72e-05	179	134	6	957c08ad4b46eb4cc1717c45056fc3db50015fdc
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous-SMG_mucous_L.0.6.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS8 PLPP5 GALNT7 FCGBP ALDH1L2 ANXA10	1.77e-05	180	134	6	8af51245ac1269f318268f574cfaddb0b8c80a53
ToppCell	5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS2 ANK2 FAT3 POTEE USH2A DDX4	1.77e-05	180	134	6	5286e66ff6b7154390b3e9c189704a71d56bc89c
ToppCell	5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS2 ANK2 FAT3 POTEE USH2A DDX4	1.77e-05	180	134	6	2b6b295b5c21b829828afae9ab4c3eb9233f6f45
ToppCell	5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS2 ANK2 FAT3 POTEE USH2A DDX4	1.77e-05	180	134	6	bf587387145a2b5e83766fbccf76eecc6d5e8241
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FAT3 ITGA10 BGN ALDH1L2 C1QTNF6 CADPS2	1.89e-05	182	134	6	ba066ff9029cc052b76e2330ec168cb2e9b7e498
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ADAM19 RNF112 P4HA3 PKHD1L1 PRKCH	1.89e-05	182	134	6	41b070085edba7a58b81c20aa4942d06f745acf8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ADAM19 RNF112 P4HA3 PKHD1L1 PRKCH	1.89e-05	182	134	6	5e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ADAM19 RNF112 P4HA3 PKHD1L1 PRKCH	1.89e-05	182	134	6	b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAT3 ITGA10 BGN PAPPA CADPS2 SCARA3	1.95e-05	183	134	6	27a57cd8ea924420e182f3d72f5b29b00dea8fa0
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF26B BGN ALDH1L2 C1S PAPPA ADAMTS14	1.95e-05	183	134	6	803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF26B BGN ALDH1L2 C1S PAPPA ADAMTS14	1.95e-05	183	134	6	6d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF26B BGN ALDH1L2 C1S PAPPA ADAMTS14	1.95e-05	183	134	6	cc7f5a17b40e8d901885174922e5fa8877643071
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B FAT3 PKHD1L1 DGKK USH2A UNC80	2.01e-05	184	134	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B FAT3 PKHD1L1 DGKK USH2A UNC80	2.01e-05	184	134	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B FAT3 PKHD1L1 DGKK USH2A UNC80	2.01e-05	184	134	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 ITGA10 BGN C1S PAPPA SCARA3	2.07e-05	185	134	6	7b1c5d99bd7a6e148524029758cee244a17f5d09
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 ITGA10 BGN C1S PAPPA SCARA3	2.07e-05	185	134	6	e9033a03d574956cf3ae228740b3166e40a6397f
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS8 SLC13A3 SUCLG2 PC ALDH6A1 ALDH7A1	2.07e-05	185	134	6	0ff4148b4701003d9d594e0da8261176fb13aa59
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLDN10 FCGBP ALDH1L2 PAK3 ALDH1A3 CADPS2	2.07e-05	185	134	6	c4ca213a59ffab183a7719c2b4bc3f658a95002d
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 ITGA10 BGN C1S PAPPA SCARA3	2.07e-05	185	134	6	578f12c6b2e33d09598dc8e022a20c8555d1325c
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ANK2 RNF112 BGN C1S PAPPA SCARA3	2.20e-05	187	134	6	e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 KIF26B C1S PAPPA ALDH1A3 SCARA3	2.40e-05	190	134	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTB ACTG1 CELSR2 PAPPA SLC25A29 CADPS2	2.47e-05	191	134	6	0a0719a0a49ae0099d61e22585ac74c10c24b4a2
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 KIF26B FAT3 C1S PAPPA SCARA3	2.55e-05	192	134	6	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 FAT3 C1S PAPPA ALDH1A3 SCARA3	2.55e-05	192	134	6	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADAM19 PLPP5 IRF4 PKHD1L1 ADAM28 ALDH7A1	2.62e-05	193	134	6	89831e1007944e47719e58f23bfef5f1944cae23
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 ACTG1 CELSR2 PAPPA SLC25A29 CADPS2	2.70e-05	194	134	6	be869e186386d03ebb670971dd24fa656b4b0edf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 ACTG1 CELSR2 PAPPA SLC25A29 CADPS2	2.70e-05	194	134	6	d602a0cdb69cd5a3e9ef61ddbab8d920557dd73e
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)-SMG_serous_(bronchial)_L.0.6.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS1 PRSS8 CLDN10 FCGBP ALDH1L2 UNC80	2.70e-05	194	134	6	a8238f312a973cadf6eb29c1e02ba898c0a20412
ToppCell	Epithelial_cells-Club_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	PLK2 CLDN10 ADAM28 FCGBP ALDH1A3 CTSE	2.78e-05	195	134	6	b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS8 SUCLG2 CLDN10 SCRN2 GMPR ALDH6A1	2.86e-05	196	134	6	d74e899cc120146dded3a20716e22c7aca4f074a
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS1 PRSS2 PRSS8 ANXA10 C1S CTSE	2.86e-05	196	134	6	784459f9f3614ead947aeb61a873dfd4cbe50641
ToppCell	distal-1-Hematologic-Plasma\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAM19 PLPP5 IRF4 PKHD1L1 ADAM28 ALDH1L2	2.94e-05	197	134	6	f5499bfa9dbc111f12563b7006bc45c2423ad0cd
ToppCell	ASK452-Epithelial-Transformed_epithelium\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	PLK2 PLPP5 PKHD1L1 TXNRD1 C1S CTSE	2.94e-05	197	134	6	b22a79a5922c865a360e2afc5506a08a512fa76a
ToppCell	Bronchial_Brush-Epithelial-Club\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	NIBAN1 PRSS8 GALNT7 CLDN10 ADAM28 FCGBP	3.03e-05	198	134	6	61292a2b5aacb6080a679a31b70a211bdec59a3b
ToppCell	tumor_Lung-Fibroblasts-COL14A1+_matrix_FBs\|tumor_Lung / Location, Cell class and cell subclass	ANK2 P4HA3 BGN C1S PAPPA SCARA3	3.03e-05	198	134	6	74f2c7ef702b25a5b99e56121229e678ed992524
ToppCell	stromal_cell\|World / Lineage and Cell class	ANK2 BGN C1S PAPPA ALDH1A3 SCARA3	3.11e-05	199	134	6	507a82d0529b5b1fa5aebcfe43db53f0b6e3f8f0
ToppCell	stromal_cell-stromal_cell\|World / Lineage and Cell class	ANK2 BGN C1S PAPPA ALDH1A3 SCARA3	3.11e-05	199	134	6	74262363a34da3a1eb55ab375fd61ddd7bb39b23
ToppCell	medial-2-mesenchymal-Myofibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANK2 P4HA3 BGN C1S PAPPA SCARA3	3.11e-05	199	134	6	95aae608fa35a9c82b12c6f18937ce636750ca44
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	FAT3 KMT2E GALNT7 MAN1A2 FAM120A ANKRD11	3.11e-05	199	134	6	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	343B-Fibroblasts-Fibroblast-F\|343B / Donor, Lineage, Cell class and subclass (all cells)	ANK2 BGN C1S PAPPA ALDH1A3 SCARA3	3.11e-05	199	134	6	b877c1d24357249781032e99d4237f72789cc9b8
ToppCell	Bronchial_Brush-Epithelial-Club\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	NIBAN1 PRSS8 GALNT7 CLDN10 ADAM28 FCGBP	3.11e-05	199	134	6	53b87edccc89a3e8a6c5166472f9ef24fcba416c
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	GALNT7 TXNRD1 MAN1A2 FAM120A ANKRD11 ALDH1A3	3.11e-05	199	134	6	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	medial-mesenchymal-Myofibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANK2 P4HA3 BGN C1S PAPPA SCARA3	3.11e-05	199	134	6	e25acdb5809aaff631cb06dbe4c7e59549a0bdb9
ToppCell	distal-1-mesenchymal-Lipofibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANK2 SLC13A3 BGN C1S PAPPA ALDH1A3	3.11e-05	199	134	6	a8293db3c42a8d30897858b49aae7acfc18663ba
ToppCell	343B-Fibroblasts-Fibroblast-F-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ANK2 BGN C1S PAPPA ALDH1A3 SCARA3	3.11e-05	199	134	6	e32fa66f3361474088ba1dd58574822537950d59
ToppCell	medial-mesenchymal-Myofibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANK2 P4HA3 BGN C1S PAPPA SCARA3	3.11e-05	199	134	6	9ebf4822ff9fa08574edec5dbf4f2a1488f34b1d
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ANK2 BGN C1S PAPPA ALDH1A3 SCARA3	3.20e-05	200	134	6	954fee8425673e76198be414f5f6c4e3597c1919
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PRSS8 RANBP6 ARMCX4 CLDN10 IBTK FCGBP	3.20e-05	200	134	6	61bae10c8b12196d9cee766897971b81cb897191
ToppCell	Biopsy_IPF-Epithelial-KRT5-/KRT17+\|Biopsy_IPF / Sample group, Lineage and Cell type	PRSS1 PRSS2 PRSS8 CLDN10 PAPPA CTSE	3.20e-05	200	134	6	2fc7a3b3aea711ad3d96fd9513f4b40533056d86
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_secretory\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NIBAN1 PRSS8 CLDN10 ADAM28 FCGBP CTSE	3.20e-05	200	134	6	8f811ddd84c037a250d124496b0fbb2e4717011c
ToppCell	TCGA-Brain-Primary_Tumor-Glioblastoma-Primary_GBM-11\|TCGA-Brain / Sample_Type by Project: Shred V9	POTEF POTEE POTEI POTEJ	3.91e-05	63	134	4	d7dc1356a60cb527fe668328d5375f352239d911
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAT3 RANBP6 FCGBP BRAT1 PCSK4	4.45e-05	129	134	5	cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 FCGBP ALDH1A3 SCARA3 TM4SF19	7.76e-05	145	134	5	8da10bc6611976e1ec85e09f04a2dc5bf6555c9e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KIF26B GALNT7 PAPPA SLC25A29 CADPS2	8.27e-05	147	134	5	b66ccc710b3c04f6fc7fed69f3c892fc110e98fc
ToppCell	mild_COVID-19_(asymptomatic)-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	NF1 CELSR2 PAK3 PAPPA MTSS2	9.69e-05	152	134	5	f944743f40ff6ed3a7a096dd53e12d3526c67c4d
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-Langerhans_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ZCWPW1 IRF4 TXNRD1 FCGBP ADAMTS14	1.03e-04	154	134	5	617ad0929d2ac0eeb7b8d9b0cba687176e684ed0
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-5\|TCGA-Colorectal / Sample_Type by Project: Shred V9	GALNT7 FCGBP TLL2 ADAM2 CTSE	1.13e-04	157	134	5	5fb41af247465aa29aa7b8edd26e3d3794766f80
ToppCell	AT1-AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SLC13A3 PAK3 C1S ALDH1A3 CTSE	1.16e-04	158	134	5	3bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CPAMD8 PRSS8 CLDN10 FCGBP ALDH1A3	1.16e-04	158	134	5	adad97e6cf479d42791c5ba9cbc5f15f469322bf
ToppCell	Club_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	NIBAN1 PLK2 ACADSB SOHLH2 CTSE	1.20e-04	159	134	5	a7bcff268b1962a561fd2848e01ae16565bce895
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 PKHD1L1 C1S USH2A UNC80	1.23e-04	160	134	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 PKHD1L1 C1S USH2A UNC80	1.23e-04	160	134	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	mild-Myeloid-CD14_Monocytes_3\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MTA2 ATP13A1 EMILIN2 SCARB2 GMPR	1.23e-04	160	134	5	a83568cd8a0b05642bacd43a8ec443e5ce314c4d
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTB C20orf173 CLDN10 ADAM28 CPNE4	1.27e-04	161	134	5	b9a63fc9becc44d305fc7c221283bf59ec06b10f
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLPP5 IRF4 PKHD1L1 ALDH1L2 TLL2	1.31e-04	162	134	5	ee6f05620f4f4ebbebd5b098afc7c20876e3d21f
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAT3 PKHD1L1 ADAM2 USH2A UNC80	1.31e-04	162	134	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLPP5 IRF4 PKHD1L1 ALDH1L2 TLL2	1.31e-04	162	134	5	9e72d468fcdd0d27b517a9e36efb35d4617a88f9
ToppCell	control-Plasmablast\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ADAM19 ANK2 IRF4 PKHD1L1 SLC6A9	1.42e-04	165	134	5	61063e0ce61bc92d5d1093be8279af03f650720b
ToppCell	Endothelial-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ADAM19 KIF26A RNF112 P4HA3 PKHD1L1	1.42e-04	165	134	5	b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 PRSS8 SLC6A9 ANXA10	1.42e-04	165	134	5	622aca1d49bd8c917b131e4f4959d9dba411d22b
ToppCell	Club_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	PLK2 CLDN10 ADAM28 ALDH1A3 MUC6	1.46e-04	166	134	5	a440aa338aa0c6cd0b5800dfa7e83f8ca16fce1a
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLPP5 ACTRT3 IRF4 ALDH1L2 CTSE	1.51e-04	167	134	5	8ec7a98b542b134f48df8fbec351693cc5cfe55c
Computational	Oxidoreductases.	ALDH1A3 ALDH6A1 ALDH7A1	1.26e-04	14	78	3	MODULE_464
Computational	Genes in the cancer module 194.	ALDH1A3 ALDH6A1 ALDH7A1	1.57e-04	15	78	3	MODULE_194
Drug	ATEE	PRSS1 PRSS2 MPEG1 ADHFE1 C1S PCSK4	3.27e-07	47	134	6	CID000002004
Drug	PCMB	PRSS1 PRSS2 SLC13A3 GMPR2 ADHFE1 C1S GMPR CTSE PCSK4	1.12e-06	178	134	9	CID000001730
Drug	AC1NSKFN	PRSS1 PRSS2 ACTRT3 ACTB ACTG1	2.13e-06	36	134	5	CID005311324
Drug	carbodiimide	PRSS1 PRSS2 ACTRT3 ACTB ACTG1 ADHFE1 C1S ALDH7A1	3.20e-06	151	134	8	CID000009864
Drug	phenylmethylsulfonyl fluoride	PRSS1 PRSS2 GALNS ACTRT3 ACTB ACTG1 ANKRD11 C1S CTSE PCSK4	3.70e-06	263	134	10	CID000004784
Drug	neuraminic acid	PRSS1 PRSS2 GALNS ZNF17 SCARB2 C1S	5.79e-06	76	134	6	CID000441037
Drug	leupeptins	PRSS1 PRSS2 CPAMD8	6.86e-06	7	134	3	CID003033938
Drug	CoA group	ACADSB ACTRT3 ACTB ACTG1 P4HA3 SUCLG2 ADHFE1 SLC27A1 SCARB2 SLC25A29 PC ALDH6A1	1.00e-05	433	134	12	CID000000317
Drug	hydroxylamine	PRSS1 PRSS2 GMPR2 GMPS ADHFE1 C1S GMPR PC TOP2B	1.47e-05	244	134	9	CID000000787
Drug	PtdIns(3,5)P	PRSS1 PRSS2 ALDH7A1	1.63e-05	9	134	3	CID000643961
Drug	Cefalonium [5575-21-3]; Down 200; 8.8uM; PC3; HT_HG-U133A	PRSS8 MAZ ADAM2 ALDH6A1 SCARA3 NUP160 CAPN15 MTSS2	1.93e-05	193	134	8	4245_DN
Drug	Etodolac [41340-25-4]; Up 200; 14uM; PC3; HT_HG-U133A	DCAF8 ZNF629 NF1 SLC35F6 PAK2 PAK3 CADPS2 ALDH6A1	2.24e-05	197	134	8	2091_UP
Drug	ML-9	ACTRT3 ACTB ACTG1 SUCLG2 IGF2R PRKCH ALDH7A1	2.68e-05	147	134	7	CID000004217
Drug	o-iodosobenzoic acid	PRSS1 PRSS2 GMPR2 GMPR PCSK4	2.99e-05	61	134	5	CID000067537
Drug	26-nor-25-doxylcholestanol	PRSS1 PRSS2 ANK2	3.18e-05	11	134	3	CID000125890
Drug	bistheonellide A	ACTRT3 ACTB ACTG1	3.18e-05	11	134	3	CID006441172
Drug	Viroisin	ACTRT3 ACTB ACTG1	3.18e-05	11	134	3	CID000119538
Drug	AP2PL	PRSS1 PRSS2 ADHFE1 TOP2B	3.19e-05	31	134	4	CID000121867
Drug	acetaldehyde	PRSS1 PRSS2 ACTRT3 ACTB ACTG1 ADHFE1 PRKCH ALDH1A3 ALDH6A1 ALDH7A1	3.26e-05	338	134	10	CID000000177
Drug	3-nitrofluoranthen-6-ol	GMPR2 GMPR	3.44e-05	2	134	2	CID000146572
Drug	3-nitrofluoranthen-9-ol	GMPR2 GMPR	3.44e-05	2	134	2	CID000146573
Drug	3-nitrofluoranthen-8-ol	GMPR2 GMPR	3.44e-05	2	134	2	CID000146567
Drug	1,3,6-trinitropyrene	GMPR2 GMPR	3.44e-05	2	134	2	CID000053229
Drug	AC1L25J4	GMPR2 GMPR	3.44e-05	2	134	2	CID000041328
Drug	2-methylcarbazole	GMPR2 GMPR	3.44e-05	2	134	2	CID000019290
Drug	m-nitrobenzamidine hydrochloride	GMPR2 GMPR	3.44e-05	2	134	2	CID000165122
Drug	2-nitrobenzofuran	GMPR2 GMPR	3.44e-05	2	134	2	CID000036328
Drug	1,3,6,8-tetranitropyrene	GMPR2 GMPR	3.44e-05	2	134	2	CID000034321
Drug	CaCl2	PRSS1 PRSS2 ACTRT3 ACTB ACTG1 SLC25A29 ALDH7A1	3.93e-05	156	134	7	CID000024854
Drug	trichloroacetic acid	PRSS1 PRSS2 GALNS ADHFE1 ALDH1A3 PC	4.13e-05	107	134	6	CID000006421
Drug	imidazole acetaldehyde	ADHFE1 ALDH1A3 ALDH7A1	4.22e-05	12	134	3	CID000150841
Drug	AC1L1J0I	ADHFE1 ALDH1A3 ALDH7A1	4.22e-05	12	134	3	CID000030201
Drug	BFDGE	ACTRT3 ACTB ACTG1	4.22e-05	12	134	3	CID000091511
Drug	4-chloro-3-ethoxy-7-guanidinoisocoumarin	PRSS1 PRSS2 C1S	5.46e-05	13	134	3	CID000196678
Drug	auxin	MTA2 ACTRT3 ACTB ACTG1 SUCLG2 ALDH1A3 ALDH6A1 ALDH7A1	5.58e-05	224	134	8	CID000000801
Drug	n-propionyl-CoA	ACADSB SLC13A3 SLC27A1 SCARB2 SLC25A29 PC ALDH6A1	5.83e-05	166	134	7	CID000001033
Drug	kabiramide C	ACTRT3 ACTB ACTG1	6.92e-05	14	134	3	CID005288658
Drug	2-aminothiophenol	PRSS1 PRSS2 CPSF4	6.92e-05	14	134	3	CID000008713
Drug	dimethyl phthalate	MTA2 PRSS2 PRSS8 ANK2 MCM8 PSMC5 MAN1A2 IGF2R SCARB2 ALDH1A3 PC CTSE TOP2B ALDH7A1	8.33e-05	714	134	14	ctd:C024629
Drug	6-[(3R,7R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptanal	ADHFE1 ALDH1A3 ALDH7A1	8.61e-05	15	134	3	CID000440673
Drug	dinitropyrene	ACTB GMPR2 GMPR	8.61e-05	15	134	3	CID003033659
Drug	malonyl-coenzyme A	ACADSB RNF112 SLC13A3 SLC27A1 SLC25A29 PC	1.03e-04	126	134	6	CID000000869
Drug	N-allylglycine	PRSS1 PRSS2	1.03e-04	3	134	2	CID000076651
Drug	N-acetyl-L-norvaline methyl ester	PRSS1 PRSS2	1.03e-04	3	134	2	CID000150916
Drug	YAKR-CK	PRSS1 PRSS2	1.03e-04	3	134	2	CID005487256
Drug	2 alpha-bromoacetoxyprogesterone	PRSS1 PRSS2	1.03e-04	3	134	2	CID000135256
Drug	methyl lignocerate	PRSS1 PRSS2	1.03e-04	3	134	2	CID000075546
Drug	GB-107	PRSS1 PRSS2	1.03e-04	3	134	2	CID000056813
Drug	mitorubrinic acid	PRSS1 PRSS2	1.03e-04	3	134	2	CID000379537
Drug	ASA-PE	PRSS1 PRSS2	1.03e-04	3	134	2	CID003037809
Drug	schizopeptin 791	PRSS1 PRSS2	1.03e-04	3	134	2	CID000636821
Drug	Lapg-nh2	PRSS1 PRSS2	1.03e-04	3	134	2	CID003082486
Drug	Methotrexate-polylysine	PRSS1 PRSS2	1.03e-04	3	134	2	CID000163214
Drug	methyl octanesulfonate	PRSS1 PRSS2	1.03e-04	3	134	2	CID000165858
Drug	3HFGB	PRSS1 PRSS2	1.03e-04	3	134	2	CID000126268
Drug	4-chlorobenzenediazonium hexafluorophosphate	PRSS1 PRSS2	1.03e-04	3	134	2	CID002723983
Drug	10-(carboxyethyl)flavin	PRSS1 PRSS2	1.03e-04	3	134	2	CID003082170
Drug	Z-Lys-CH2Cl	PRSS1 PRSS2	1.03e-04	3	134	2	CID000127335
Drug	2,6-dimethyl-3-pyridinol	PRSS1 PRSS2	1.03e-04	3	134	2	CID000070732
Drug	N-phosphopyridoxyl-L-serine	PRSS1 PRSS2	1.03e-04	3	134	2	CID000195946
Drug	Z-Arg-OH	PRSS1 PRSS2	1.03e-04	3	134	2	CID000071055
Drug	p-amidinophenylpyruvate	PRSS1 PRSS2	1.03e-04	3	134	2	CID000444106
Drug	v 1194	PRSS1 PRSS2	1.03e-04	3	134	2	CID000074702
Drug	L-TAPA	PRSS1 PRSS2	1.03e-04	3	134	2	CID000193734
Drug	diphenylcarbamyl chloride	PRSS1 PRSS2 GALNS	1.06e-04	16	134	3	CID000065741
Drug	glycurone	GALNS ALDH1A3 ALDH7A1	1.06e-04	16	134	3	CID000003483
Drug	AC1L9JUM	ACTG1 GMPR2 GMPR	1.06e-04	16	134	3	CID000446587
Drug	chloral hydrate	PRSS1 PRSS2 PSMC5 ADHFE1 ALDH1A3 ALDH7A1	1.17e-04	129	134	6	CID000002707
Drug	propynal	ADHFE1 ALDH1A3 ALDH7A1	1.28e-04	17	134	3	CID000012222
Drug	Nsc687160	ACTRT3 ACTB ACTG1	1.52e-04	18	134	3	CID005459290
Drug	Fp-O	PRSS1 PRSS2 PRSS8 RNF112 C1S	1.64e-04	87	134	5	CID000024267
Drug	Florfenicol [73231-34-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A	DCAF8 LIMD1 MAZ IRF4 CELSR2 CTSE ALDH7A1	1.70e-04	197	134	7	5300_UP
Drug	Neomycin sulfate [1405-10-3]; Up 200; 4.2uM; MCF7; HT_HG-U133A	KIF26B ITGA10 SLC13A3 SLC6A9 NF1 GMPR ALDH7A1	1.75e-04	198	134	7	7221_UP
Drug	Streptomycin sulfate [3810-74-0]; Up 200; 2.8uM; PC3; HT_HG-U133A	DCAF8 BGN NF1 ALDH6A1 MUC6 NUP160 ALDH7A1	1.75e-04	198	134	7	5837_UP
Drug	tolytoxin	ACTRT3 ACTB ACTG1	1.80e-04	19	134	3	CID006440827
Drug	m2-19	ACTRT3 ACTB ACTG1	1.80e-04	19	134	3	CID000079129
Drug	5'IATR	ACTRT3 ACTB ACTG1	1.80e-04	19	134	3	CID000074997
Drug	5-HIAL	ADHFE1 ALDH1A3 ALDH7A1	1.80e-04	19	134	3	CID000074688
Drug	Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A	IRF4 BGN NF1 PRSS21 GMPR ALDH7A1 ZNF304	1.86e-04	200	134	7	5513_UP
Drug	4-Amino-3-nitrobenzoic acid	PRSS1 PRSS2	2.05e-04	4	134	2	CID000074115
Drug	4-ethylpiperidine	PRSS1 PRSS2	2.05e-04	4	134	2	CID000076704
Drug	torquatone	PRSS1 PRSS2	2.05e-04	4	134	2	CID000256516
Drug	mGBSOM	PRSS1 PRSS2	2.05e-04	4	134	2	CID003080804
Drug	Ba-O	PRSS1 PRSS2	2.05e-04	4	134	2	CID000002280
Drug	nitromethanamine	GMPR2 GMPR	2.05e-04	4	134	2	CID000061148
Drug	1-amino-8-nitropyrene	GMPR2 GMPR	2.05e-04	4	134	2	CID000108113
Drug	methyl p-nitrobenzoate	GMPR2 GMPR	2.05e-04	4	134	2	CID000012083
Drug	NSC-13568	PRSS1 PRSS2	2.05e-04	4	134	2	CID000224783
Drug	iron phthalocyanine	C1S PC	2.05e-04	4	134	2	CID000123025
Drug	xylaric acid	PRSS1 PRSS2	2.05e-04	4	134	2	CID003084064
Drug	anilino acetate	GMPR2 GMPR	2.05e-04	4	134	2	CID000153367
Drug	AC1LAOUV	PRSS1 PRSS2	2.05e-04	4	134	2	CID000492408
Drug	5'-S-propynyl-5'-thioadenosine	PRSS1 PRSS2	2.05e-04	4	134	2	CID000492409
Drug	AC1Q5JO7	PRSS1 PRSS2	2.05e-04	4	134	2	CID000128324
Drug	Dsdgk	PRSS1 PRSS2	2.05e-04	4	134	2	CID000130454
Drug	c0458	GMPR2 GMPR	2.05e-04	4	134	2	CID009543178
Drug	NSC-45351	PRSS1 PRSS2	2.05e-04	4	134	2	CID000018046
Drug	indomethacin-NHS	PRSS1 PRSS2	2.05e-04	4	134	2	CID000128571
Drug	bromomesaconic acid	PRSS1 PRSS2	2.05e-04	4	134	2	CID006449799
Drug	N-carbobenzoxyglycine vinyl ester	PRSS1 PRSS2	2.05e-04	4	134	2	CID000047309
Disease	Uveoretinal Coloboma	ACTB ACTG1 ALDH7A1	2.57e-06	7	125	3	C4554007
Disease	Moyamoya disease (implicated_via_orthology)	ACTB ACTG1 POTEKP	4.09e-06	8	125	3	DOID:13099 (implicated_via_orthology)
Disease	autosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)	ACTB ACTG1 POTEKP	4.09e-06	8	125	3	DOID:0110550 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome 1 (implicated_via_orthology)	ACTB ACTG1 POTEKP	4.09e-06	8	125	3	DOID:0081112 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (implicated_via_orthology)	ACTB ACTG1 POTEKP	4.09e-06	8	125	3	DOID:14004 (implicated_via_orthology)
Disease	Congenital ocular coloboma (disorder)	ACTB ACTG1 ALDH7A1	6.12e-06	9	125	3	C0009363
Disease	intestinal atresia (implicated_via_orthology)	ACTB ACTG1 POTEKP	8.71e-06	10	125	3	DOID:10486 (implicated_via_orthology)
Disease	patent ductus arteriosus (implicated_via_orthology)	ACTB ACTG1 POTEKP	8.71e-06	10	125	3	DOID:13832 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome	ACTB ACTG1	1.78e-05	2	125	2	cv:C1853623
Disease	Iris Coloboma with Ptosis, Hypertelorism, and Mental Retardation	ACTB ACTG1	1.78e-05	2	125	2	C1855722
Disease	Fryns-Aftimos Syndrome	ACTB ACTG1	1.78e-05	2	125	2	C1853623
Disease	PANCREATITIS, HEREDITARY	PRSS1 PRSS2	1.77e-04	5	125	2	167800
Disease	Hereditary pancreatitis	PRSS1 PRSS2	1.77e-04	5	125	2	cv:C0238339
Disease	Autosomal Dominant Hereditary Pancreatitis	PRSS1 PRSS2	1.77e-04	5	125	2	C4080064
Disease	survival time, prostate carcinoma	SUCLG2 DGKK	2.64e-04	6	125	2	EFO_0000714, EFO_0001663
Disease	Hereditary pancreatitis	PRSS1 PRSS2	3.69e-04	7	125	2	C0238339
Disease	PARTINGTON X-LINKED MENTAL RETARDATION SYNDROME	BRWD3 PAK3	4.90e-04	8	125	2	C0796250
Disease	Pancreatitis, Chronic	PRSS1 PRSS2	6.29e-04	9	125	2	C0149521
Disease	Neurodevelopmental Disorders	ANK2 KMT2E CDC42BPB ANKRD11	6.70e-04	93	125	4	C1535926
Disease	Congenital neurologic anomalies	ACTB ACTG1	7.84e-04	10	125	2	C0497552
Disease	Cranioschisis	ACTB ACTG1	7.84e-04	10	125	2	C0265541
Disease	3-methylglutarylcarnitine (2) measurement	SLC13A3 SUCLG2	9.55e-04	11	125	2	EFO_0800074
Disease	diffuse large B-cell lymphoma	IRF4 CDC42BPB	1.57e-03	14	125	2	EFO_0000403
Disease	osteoarthritis, hip, osteoarthritis, knee	RWDD2B NF1 NUP160	2.34e-03	62	125	3	EFO_0004616, EFO_1000786
Disease	Myeloid Leukemia	KMT2E TOP2B	2.61e-03	18	125	2	C0023470
Disease	Leukemia, Monocytic, Chronic	KMT2E TOP2B	2.61e-03	18	125	2	C0023466
Disease	breast carcinoma (is_marker_for)	PRSS8 ADAM28 IGF2R	2.80e-03	66	125	3	DOID:3459 (is_marker_for)
Disease	skin sensitivity to sun	IRF4 ANKRD11	2.90e-03	19	125	2	EFO_0004795
Disease	Colorectal Carcinoma	PRSS1 CPAMD8 ADAM19 GALNS ANK2 PSMC5 TXNRD1 NF1 ACTL9	3.07e-03	702	125	9	C0009402
Disease	disease of metabolism (implicated_via_orthology)	YTHDF2 YTHDF3	3.55e-03	21	125	2	DOID:0014667 (implicated_via_orthology)
Disease	Ovarian Failure, Premature	MCM8 SOHLH2	3.55e-03	21	125	2	C0085215

Protein segments in the cluster

Peptide	Gene	Start	Entry
GAEVKGVCTEAGMYA	PSMC5	356	P62195
MLATGGFLQGDEADC	BRAT1	806	Q6PJG6
MDAQMLGGALQGFDC	ANXA10	21	Q9UJ72
LGGALQGFDCDKDML	ANXA10	26	Q9UJ72
DRDSCMGSGFKMGEA	ANKRD11	1126	Q6UB99
GECNKRDNTSTMGGF	DDX4	71	Q9NQI0
ANDTMCGKLFCQGGS	ADAM28	556	Q9UKQ2
TCGGADIGTAMAKDE	ALDH7A1	251	P49419
DNGSGMIKAGVAGCR	ACTRT3	11	Q9BYD9
VAGDTFGNCGKDMNG	ADAM19	546	Q9H013
TFQGKMCDANYAGGV	ADAM2	281	Q99965
DNGSGMCKAGFAGDD	POTEKP	11	Q9BYX7
MCKAGFAGDDAPQAV	POTEKP	16	Q9BYX7
AALVVDNGSGMCKAG	ACTB	6	P60709
DNGSGMCKAGFAGDD	ACTB	11	P60709
MCKAGFAGDDAPRAV	ACTB	16	P60709
AALVIDNGSGMCKAG	ACTG1	6	P63261
DNGSGMCKAGFAGDD	ACTG1	11	P63261
MCKAGFAGDDAPRAV	ACTG1	16	P63261
GMGAVFFNKGENCIA	ALDH1L2	716	Q3SY69
MCGDGTNDVGALKHA	ATP13A1	861	Q9HD20
MGTGTCKVGFAGQAS	ACTL9	56	Q8TC94
GAKLECGGSAMEDKG	ALDH1A3	376	P47895
NMIEGQGHGAVFDCK	BRWD3	506	Q6RI45
GIAAQMLGLAQGCFD	ACADSB	296	P45954
SNKMACLGEGAAGAK	ANKRD26P1	241	Q6NSI1
PLGFGGKSCAQEMAN	CELSR2	1601	Q9HCU4
DFCLGITGGFDNKML	CFAP161	146	Q6P656
FALFGMKCTKVGGSD	CLDN10	96	P78369
GGNTNAMCKVGAGAD	ARMCX4	341	Q5H9R4
SMKADDKCGVCGGDN	ADAMTS14	696	Q8WXS8
KTIFDLSCMGFQGNG	CDK5RAP2	676	Q96SN8
MNGAGFQKGLTCESC	MTA2	356	O94776
DGSCEGKMTNFSFGG	MPEG1	366	Q2M385
GDDCFQVGKVAYDMG	P4HA3	181	Q7Z4N8
KEAGFLMGASCGGGN	CAPN15	686	O75808
CGGGNMKVDDSAYES	CAPN15	696	O75808
KASSDVMLNGFGGDA	ANK2	1241	Q01484
VGAAFGAAGQRCMAL	ALDH6A1	306	Q02252
QMCGLCGNFDGKVTN	MUC6	171	Q6W4X9
DNGSGMCKAGFAGDD	POTEF	711	A5A3E0
MCKAGFAGDDAPRAV	POTEF	716	A5A3E0
GMDGSVKLTDFGFCA	PAK3	411	O75914
YGQDSGNEMGAASCI	DGKK	1121	Q5KSL6
AEGRQKAFGTCGSHM	OR2B3	231	O76000
GSGGCDMANKENELA	KATNBL1	91	Q9H079
SKGVFGAGQACQAMG	LIMD1	476	Q9UGP4
DQGICGIDEFDKMGN	MCM8	511	Q9UJA3
EFGMSAVSCGNGKLR	IRF4	11	Q15306
TGFSKDLGICGAMDI	MTMR8	646	Q96EF0
NGGQKICILAMDGAG	IBTK	401	Q9P2D0
MAGASGDKELGLGCS	KATNIP	646	O60303
MGDDSFNKAAPIKGC	KIF26B	1346	Q2KJY2
DGMQFCSSGFQGLDI	CTSE	346	P14091
EVAAMANNGFCGVGV	PCSK4	206	Q6UW60
METAEKECGALGGLF	MTSS2	1	Q765P7
GVNDFCPMGFGVKRA	BGN	316	P21810
QFMEGDKGGVVNCLE	DCAF8	471	Q5TAQ9
KQLESAMRSCDFGDG	KCNS2	421	Q9ULS6
GGGFRISESKCLMQD	KMT2E	1096	Q8IZD2
KGTGEVCPMAAAAAA	MAZ	426	P56270
ADGCIFSFGHMSLGK	KIF26A	461	Q9ULI4
GDVAKAFGAGADFVM	GMPR2	226	Q9P2T1
GVDMALFANDACGQP	FAM120A	776	Q9NZB2
LADFGSCLKMNDDGT	CDC42BPB	216	Q9Y5S2
KLACGGDGDTTENQM	OR2I1P	186	Q8NGU4
DDMNKINGDGCSLFC	PAPPA	961	Q13219
MKFEEKCGDNGSIVG	FADS2B	1	A8MWK0
DNGSGMCKAGFAGDD	POTEE	711	Q6S8J3
MCKAGFAGDDAPRAV	POTEE	716	Q6S8J3
LGMEGSVKLTDFGFC	PAK2	376	Q13177
FLCGKQTTFEGGMRE	GALNS	306	P34059
GDCDMGCVVQASGLF	FBXL19-AS1	81	Q494R0
GGFLCNVADKSGAME	FASTKD5	666	Q7L8L6
MALCNGDSKLENAGG	GMPS	1	P49915
NLDGCFDMATGQFAA	C1QTNF6	171	Q9BXI9
DVGCGTGILSMFAAK	PRMT3	261	O60678
FFKGCVLDVCMGGGD	FCGBP	1901	Q9Y6R7
SFFKGCVLDVCMGGG	FCGBP	3101	Q9Y6R7
ETAYCIDSMGKTNGG	GALNT7	541	Q86SF2
GLFVSAKGDGCCLMQ	CPAMD8	1476	Q8IZJ3
KEADFLGGMECTLGQ	CPNE4	106	Q96A23
LMAKATDGGGRFCQS	FAT3	3101	Q8TDW7
DDMKNCGVNCSGDVF	C1S	166	P09871
GLQGGCMFFNAVKEG	CADPS2	551	Q86UW7
MALDFLAGCAGGVAG	SLC25A29	1	Q8N8R3
LACFSGGMIALGAED	MAN1C1	451	Q9NR34
YVEGGDCATLLKNMG	MAST3	446	O60307
GMFALGADGSRADKA	MAN1A2	466	O60476
SLLETDGDGGFMACA	ITGA10	111	O75578
PGMDKSGAAVCEFFL	CPSF4	31	O95639
NCRAGENAGMGRFTK	EMILIN2	631	Q9BXX0
DLGSGCGATAIAAKM	ETFBKMT	121	Q8IXQ9
GDVAKAFGAGADFVM	GMPR	226	P36959
SCCFQGMNSGSELGK	C20orf173	46	Q96LM9
LLLGGGFAMAKGCEE	SLC13A3	431	Q8WWT9
GFAMAKGCEESGLSV	SLC13A3	436	Q8WWT9
MKVRSAGGDGDALCV	SCARA3	1	Q6AZY7
CFSSGKDDMDFAGNV	CEBPZ	856	Q03701
AVGGGSTMDTCKAAN	ADHFE1	136	Q8IWW8
NGLLKMNFTGGDTCH	IGF2R	1306	P11717
ARNCGAFGMKNNGDL	USH2A	416	O75445
SNMFCVGFLEGGKDS	PRSS3P2	181	Q8NHM4
DLAGSCRGVKVMFNG	TOP2B	266	Q02880
DKESGICMDSGGFRT	SCRN2	271	Q96FV2
FCAVLAGGKENGQMA	NBEAL2	206	Q6ZNJ1
LVIDNGSGMCKAGFA	POTEJ	671	P0CG39
LACKGQGSMDEGTAD	SCARB2	456	Q14108
DNGSGMCKAGFAGDD	POTEI	711	P0CG38
MCKAGFAGDDAPRAV	POTEI	716	P0CG38
MVCAGYVEGGKDACQ	PRSS8	221	Q16651
DGGKMAAAGALERSF	NUP160	31	Q12769
FAKSIEVMGDGCLND	RANBP6	781	O60518
MGCAEGKAVAAAAPT	TXNRD1	1	Q16881
VGCGAIGCEMLKNFA	UBA6	466	A0AVT1
GNIACFVNGAGLAMA	SUCLG2	301	Q96I99
SVNGSGHFCGVAEMK	YTHDF3	466	Q7Z739
CMIRHGKELGGESNF	SH3GL1	96	Q99961
GMGSGLDFAETSCAQ	ZCWPW1	121	Q9H0M4
LGFCMEPVTDNKAGF	UNC80	866	Q8N2C7
GFMEGKIDACKGDSG	TMPRSS11F	376	Q6ZWK6
MGGSASSQLDEGKCA	NIBAN1	1	Q9BZQ8
GAGLAATVGCMEKEE	RNF112	601	Q9ULX5
IANMDGKVGSCGFNS	SLC27A1	396	Q6PCB7
DGHSILAGGMSKFVC	PWP2	616	Q15269
KNICEGGEEMDNKFG	POLR2A	151	P24928
MGKAAAAVAFGAEVG	PLPP5	1	Q8NEB5
EATCGGDMNKDAGQI	TLL2	461	Q9Y6L7
NMFGETLHKAVQGCG	NF1	441	P21359
MELSFGQFASQGCLG	SLC6A9	156	P48067
NNMFCVGFLEGGKDS	PRSS2	181	P07478
EIGSDQFGGCVMFHA	PKHD1L1	2431	Q86WI1
GGTDSTEGLCNMGFA	RRN3P2	251	A6NIE6
LNTKGCGDVFQMFFG	RWDD2B	301	P57060
FMAEGCGGSKEHSFQ	SLC35F6	31	Q8N357
NMGQDPDCFGKSEGE	nan	286	Q3C1V9
ACFDSGDTICKGGEM	SLC9C2	886	Q5TAH2
DIFGDMVCAGNAQGG	PRSS21	216	Q9Y6M0
MVCAGNAQGGKDACF	PRSS21	221	Q9Y6M0
MLFSCGDEGKAFLDT	ZNF304	221	Q9HCX3
KMCEQALGKGCGADS	PLK2	16	Q9NYY3
SNMFCVGFLEGGKDS	PRSS1	181	P07477
MNGNNAAAGKSVGEC	ZFAND4	631	Q86XD8
CLVCGKGFNDEGIFM	ZNF629	571	Q9UEG4
NFKGCISGHGMDIAL	SOHLH2	106	Q9NX45
SGAGVAAMLACAQAG	PC	776	P11498
NLTCMQGGKDFTGDS	ZNF17	146	P17021
VNGSGHFCGVAEMKS	YTHDF2	461	Q9Y5A9
GVALKDGPFCMFDVS	TM4SF19	116	Q96DZ7
ADFGMCKEGICNGVT	PRKCH	496	P24723