Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

COP1 TTC3 CBLL2 LMO7 TRIM38 TRIM73 TRIM74

9.63e-05473467GO:0004842
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

COP1 TTC3 CBLL2 LMO7 TRIM38 TRIM73 TRIM74

1.57e-04512467GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

COP1 TTC3 CBLL2 LMO7 TRIM38 TRIM73 TRIM74

1.99e-04532467GO:0016755
GeneOntologyBiologicalProcessprotein ubiquitination

COP1 LIMK1 RPS27A TTC3 CBLL2 LMO7 TRIM38 TRIM73 TRIM74

4.42e-05811449GO:0016567
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

COP1 LIMK1 RPS27A TTC3 CBLL2 LMO7 TRIM38 TRIM73 TRIM74

9.28e-05893449GO:0032446
DomainZnf_RING_CS

COP1 RNF222 CBLL2 TRIM38 TRIM73 TRIM74

2.16e-06163446IPR017907
DomainZF_RING_1

COP1 RNF222 TTC3 CBLL2 TRIM38 TRIM73 TRIM74

4.85e-06291447PS00518
DomainZF_RING_2

COP1 RNF222 TTC3 CBLL2 TRIM38 TRIM73 TRIM74

5.67e-06298447PS50089
DomainRING

COP1 RNF222 TTC3 CBLL2 TRIM38 TRIM73 TRIM74

6.60e-06305447SM00184
Domain-

COP1 PHF6 RNF222 TTC3 CBLL2 TRIM38 TRIM73 TRIM74

8.69e-064494483.30.40.10
DomainZnf_RING

COP1 RNF222 TTC3 CBLL2 TRIM38 TRIM73 TRIM74

1.02e-05326447IPR001841
DomainZnf_RING/FYVE/PHD

COP1 PHF6 RNF222 TTC3 CBLL2 TRIM38 TRIM73 TRIM74

1.02e-05459448IPR013083
Domainzf-C3HC4

COP1 RNF222 TTC3 TRIM38 TRIM73 TRIM74

1.31e-05223446PF00097
DomainLIM

LIMK1 LIMK2 WTIP LMO7

2.07e-0569444PF00412
Domain-

LIMK1 LIMK2 WTIP LMO7

2.19e-05704442.10.110.10
DomainLIM_DOMAIN_2

LIMK1 LIMK2 WTIP LMO7

2.32e-0571444PS50023
DomainZnf_LIM

LIMK1 LIMK2 WTIP LMO7

2.32e-0571444IPR001781
DomainLIM_DOMAIN_1

LIMK1 LIMK2 WTIP LMO7

2.32e-0571444PS00478
DomainLIM

LIMK1 LIMK2 WTIP LMO7

2.32e-0571444SM00132
DomainEGF-like_CS

SCUBE1 MALRD1 MEGF9 LRP1B EGFL6 EPHA5

3.18e-05261446IPR013032
DomainEGF_2

SCUBE1 MALRD1 MEGF9 LRP1B EGFL6 EPHA5

3.46e-05265446PS01186
DomainZnf_C3HC4_RING-type

COP1 RNF222 TTC3 TRIM73 TRIM74

5.07e-05172445IPR018957
Domainzf-RING_9

RUBCN PLEKHM1

5.40e-055442PF13901
DomainDUF4206

RUBCN PLEKHM1

5.40e-055442SM01175
DomainZf-RING_9

RUBCN PLEKHM1

5.40e-055442IPR025258
DomainZnf-RING_LisH

RNF222 TRIM73 TRIM74

6.94e-0534443IPR027370
Domainzf-RING_UBOX

RNF222 TRIM73 TRIM74

6.94e-0534443PF13445
DomainLDLR_class-A_CS

CORIN MALRD1 LRP1B

1.13e-0440443IPR023415
DomainLdl_recept_a

CORIN MALRD1 LRP1B

1.62e-0445443PF00057
Domain-

CORIN MALRD1 LRP1B

1.73e-04464434.10.400.10
DomainLDLRA_1

CORIN MALRD1 LRP1B

1.96e-0448443PS01209
DomainLDrepeatLR_classA_rpt

CORIN MALRD1 LRP1B

2.08e-0449443IPR002172
DomainLDLa

CORIN MALRD1 LRP1B

2.08e-0449443SM00192
DomainLDLRA_2

CORIN MALRD1 LRP1B

2.08e-0449443PS50068
DomainEGF

SCUBE1 MALRD1 MEGF9 LRP1B EGFL6

2.20e-04235445SM00181
DomainEGF-like_dom

SCUBE1 MALRD1 MEGF9 LRP1B EGFL6

2.87e-04249445IPR000742
DomainEGF_1

SCUBE1 MALRD1 MEGF9 LRP1B EGFL6

3.21e-04255445PS00022
DomainGrowth_fac_rcpt_

SCUBE1 LRP1B EGFL6 EPHA5

4.90e-04156444IPR009030
DomainBBOX

TRIM38 TRIM73 TRIM74

5.73e-0469443SM00336
Domain-

TRIM38 TRIM73 TRIM74

6.23e-04714434.10.45.10
Domainzf-B_box

TRIM38 TRIM73 TRIM74

6.50e-0472443PF00643
DomainMAM

MALRD1 EGFL6

7.21e-0417442SM00137
DomainMAM

MALRD1 EGFL6

8.10e-0418442PF00629
DomainRUN

RUBCN PLEKHM1

8.10e-0418442SM00593
DomainMAM_dom

MALRD1 EGFL6

8.10e-0418442IPR000998
DomainMAM_2

MALRD1 EGFL6

8.10e-0418442PS50060
DomainZF_BBOX

TRIM38 TRIM73 TRIM74

8.83e-0480443PS50119
DomainRUN

RUBCN PLEKHM1

9.04e-0419442PS50826
DomainRun_dom

RUBCN PLEKHM1

9.04e-0419442IPR004012
DomainRUN

RUBCN PLEKHM1

9.04e-0419442PF02759
DomainZnf_B-box

TRIM38 TRIM73 TRIM74

9.16e-0481443IPR000315
DomainEGF_CA

SCUBE1 LRP1B EGFL6

1.09e-0386443PF07645
DomainEPHD

PHF6 RAI1

1.22e-0322442PS51805
DomainEGF_Ca-bd_CS

SCUBE1 LRP1B EGFL6

1.54e-0397443IPR018097
DomainEphrin_rec_like

SCUBE1 EPHA5

1.57e-0325442SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

SCUBE1 EPHA5

1.57e-0325442IPR011641
DomainEGF_CA

SCUBE1 LRP1B EGFL6

1.63e-0399443PS01187
DomainASX_HYDROXYL

SCUBE1 LRP1B EGFL6

1.68e-03100443PS00010
DomainTNFR

TNFRSF1A MEGF9

1.70e-0326442SM00208
DomaincEGF

SCUBE1 LRP1B

1.70e-0326442IPR026823
DomaincEGF

SCUBE1 LRP1B

1.70e-0326442PF12662
DomainEGF-type_Asp/Asn_hydroxyl_site

SCUBE1 LRP1B EGFL6

1.99e-03106443IPR000152
DomainZINC_FINGER_C2H2_2

ZFHX3 ZNF276 ZNF285 CBLL2 CASZ1 ZFP41 ZNF280C

2.07e-03775447PS50157
DomainZINC_FINGER_C2H2_1

ZFHX3 ZNF276 ZNF285 CBLL2 CASZ1 ZFP41 ZNF280C

2.10e-03777447PS00028
DomainEGF_3

SCUBE1 MALRD1 LRP1B EGFL6

2.24e-03235444PS50026
DomainZnf_C2H2-like

ZFHX3 ZNF276 ZNF285 CBLL2 CASZ1 ZFP41 ZNF280C

2.40e-03796447IPR015880
DomainZnf_C2H2

ZFHX3 ZNF276 ZNF285 CBLL2 CASZ1 ZFP41 ZNF280C

2.56e-03805447IPR007087
DomainZnF_C2H2

ZFHX3 ZNF276 ZNF285 CBLL2 CASZ1 ZFP41 ZNF280C

2.62e-03808447SM00355
DomainTNFR/NGFR_Cys_rich_reg

TNFRSF1A MEGF9

2.73e-0333442IPR001368
DomainEGF_CA

SCUBE1 LRP1B EGFL6

2.96e-03122443SM00179
DomainEGF-like_Ca-bd_dom

SCUBE1 LRP1B EGFL6

3.10e-03124443IPR001881
DomainPkinase_Tyr

LIMK1 LIMK2 EPHA5

3.47e-03129443PF07714
DomainSer-Thr/Tyr_kinase_cat_dom

LIMK1 LIMK2 EPHA5

4.19e-03138443IPR001245
DomainPDZ

LIMK1 LIMK2 LMO7

4.45e-03141443PF00595
DomainPDZ

LIMK1 LIMK2 LMO7

5.09e-03148443SM00228
Domain-

LIMK1 LIMK2 LMO7

5.28e-031504432.30.42.10
Pubmed

Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.

LIMK1 TRIM73 TRIM74

2.16e-08546320049703
Pubmed

LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice.

LIMK1 LIMK2

1.71e-06246223239465
Pubmed

The small GTPase RhoA regulates the LIMK1/2-cofilin pathway to modulate cytoskeletal dynamics in oocyte meiosis.

LIMK1 LIMK2

1.71e-06246229319181
Pubmed

The Diagnostic and Prognostic Value of LIMK1/2: A Pan-Cancer Analysis.

LIMK1 LIMK2

1.71e-06246234686503
Pubmed

LIMK1 and LIMK2 are important for metastatic behavior and tumor cell-induced angiogenesis of pancreatic cancer cells.

LIMK1 LIMK2

1.71e-06246220047470
Pubmed

Phosphorylated LIM kinases colocalize with gamma-tubulin in centrosomes during early stages of mitosis.

LIMK1 LIMK2

1.71e-06246218000399
Pubmed

Involvement of LIMK1/2 in actin assembly during mouse embryo development.

LIMK1 LIMK2

1.71e-06246229943641
Pubmed

Different activity regulation and subcellular localization of LIMK1 and LIMK2 during cell cycle transition.

LIMK1 LIMK2

1.71e-06246216455074
Pubmed

Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain.

LIMK1 LIMK2

1.71e-06246228669900
Pubmed

Cloning and biochemical characterization of LIMK-2, a protein kinase containing two LIM domains.

LIMK1 LIMK2

1.71e-0624629089416
Pubmed

LIM kinases: function, regulation and association with human disease.

LIMK1 LIMK2

1.71e-06246217294230
Pubmed

Rubicon and PLEKHM1 negatively regulate the endocytic/autophagic pathway via a novel Rab7-binding domain.

RUBCN PLEKHM1

1.71e-06246220943950
Pubmed

Self-association of LIM-kinase 1 mediated by the interaction between an N-terminal LIM domain and a C-terminal kinase domain.

LIMK1 LIMK2

1.71e-0624628980133
Pubmed

Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation.

LIMK1 LIMK2

1.71e-06246225344584
Pubmed

Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion.

LIMK1 LIMK2

1.71e-06246231641031
Pubmed

GPER stabilizes F-actin cytoskeleton and activates TAZ via PLCβ-PKC and Rho/ROCK-LIMK-Cofilin pathway.

LIMK1 LIMK2

5.13e-06346231277940
Pubmed

Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization.

LIMK1 LIMK2

5.13e-06346226880202
Pubmed

NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms.

LIMK1 LIMK2

5.13e-06346234407403
Pubmed

LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP.

LIMK1 LIMK2

5.13e-06346227116935
Pubmed

Regulation of ADF/cofilin phosphorylation and synaptic function by LIM-kinase.

LIMK1 LIMK2

5.13e-06346215458846
Pubmed

Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion.

LIMK1 LIMK2

5.13e-06346218332102
Pubmed

Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution.

TRIM73 TRIM74

5.13e-06346226196062
Pubmed

TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.

TRIM73 TRIM74

5.13e-06346222872646
Pubmed

Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs.

LIMK1 LIMK2

1.03e-0544628537403
Pubmed

Keratinocyte migration in the developing eyelid requires LIMK2.

LIMK1 LIMK2

1.03e-05446223071748
Pubmed

A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability.

LIMK1 LIMK2

1.03e-05446222883572
Pubmed

TPPP acts downstream of RhoA-ROCK-LIMK2 to regulate astral microtubule organization and spindle orientation.

LIMK1 LIMK2

1.71e-05546222328514
Pubmed

Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase.

TRIM73 TRIM74

1.71e-05546218398435
Pubmed

LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection.

LIMK1 LIMK2

1.71e-05546221321123
Pubmed

Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells.

LIMK1 LIMK2

2.56e-05646211418599
Pubmed

TRIM50 regulates Beclin 1 proautophagic activity.

TRIM73 TRIM74

2.56e-05646229604308
Pubmed

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

LIMK1 LIMK2

2.56e-05646210436159
Pubmed

Nf1 RasGAP inhibition of LIMK2 mediates a new cross-talk between Ras and Rho pathways.

LIMK1 LIMK2

2.56e-05646223082153
Pubmed

Timp3 deficient mice show resistance to developing breast cancer.

TNFRSF1A TIMP4

2.56e-05646225807548
Pubmed

TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.

TRIM73 TRIM74

2.56e-05646236178239
Pubmed

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization.

LIMK1 LIMK2

2.56e-0564629655398
Pubmed

Role for p21-activated kinase PAK4 in development of the mammalian heart.

LIMK1 LIMK2

2.56e-05646222173944
Pubmed

Altered expression of CDC42 signaling pathway components in cortical layer 3 pyramidal cells in schizophrenia.

LIMK1 LIMK2

3.58e-05746225981171
Pubmed

Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.

TRIM73 TRIM74

3.58e-05746226025256
Pubmed

Filamin-A regulates actin-dependent clustering of HIV receptors.

LIMK1 LIMK2

4.77e-05846217572668
Pubmed

Activation of LIM kinases by myotonic dystrophy kinase-related Cdc42-binding kinase alpha.

LIMK1 LIMK2

4.77e-05846211340065
Pubmed

Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin.

LIMK1 LIMK2

6.12e-05946215660133
Pubmed

Coordination of Cellular Dynamics Contributes to Tooth Epithelium Deformations.

LIMK1 LIMK2

6.12e-05946227588418
Pubmed

LIMK1 and LIMK2 regulate cortical development through affecting neural progenitor cell proliferation and migration.

LIMK1 LIMK2

6.12e-05946231319858
Pubmed

Autotaxin/lysophospholipase D-mediated lysophosphatidic acid signaling is required to form distinctive large lysosomes in the visceral endoderm cells of the mouse yolk sac.

LIMK1 LIMK2

6.12e-05946219808661
Pubmed

PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection.

RUBCN PLEKHM1

7.65e-051046225500191
Pubmed

Functional proteomics mapping of a human signaling pathway.

ZMYM2 LIMK2 RPS27A TTC3 RUBCN CGA

1.23e-0459146615231748
Pubmed

Sox6 and Otx2 control the specification of substantia nigra and ventral tegmental area dopamine neurons.

CORIN EPHA5

1.32e-041346225127144
Pubmed

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure.

LIMK1 LIMK2

1.32e-041346217229766
Pubmed

Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice.

LIMK1 LIMK2

1.32e-041346230333726
Pubmed

Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development.

LIMK1 LIMK2

1.54e-041446220534669
Pubmed

Chemokine coreceptor signaling in HIV-1 infection and pathogenesis.

LIMK1 LIMK2

1.54e-041446220041213
Pubmed

Identification of markers of the midface.

LIMK1 TNFRSF1A

1.78e-041546215615879
Pubmed

Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.

LIMK1 LIMK2

1.78e-041546222810622
Pubmed

LIM kinase 2 is widely expressed in all tissues.

LIMK1 LIMK2

2.03e-041646216399995
Pubmed

Activation of Rho GTPases in Smith-Lemli-Opitz syndrome: pathophysiological and clinical implications.

LIMK1 LIMK2

2.03e-041646220067919
Pubmed

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.

TRIM73 TRIM74

2.03e-041646222792322
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZMYM2 LIMK1 RPS27A FUT8 TTC3 MEGF9 LMO7 LRP1B

2.54e-04128546835914814
Pubmed

Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function.

LIMK1 LIMK2

2.58e-041846230833597
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

ZMYM2 ZFHX3 RAI1

3.49e-0410346332744500
Pubmed

Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling.

IFIT2 CGA

5.04e-042546236458554
Pubmed

Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death.

LIMK1 LIMK2

5.45e-042646217875933
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZMYM2 ZFHX3 LIMK1 LIMK2 ZFP41 ZNF280C

6.55e-0480846620412781
Pubmed

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.

RPS27A TECRL MEGF9 CCDC82 DQX1 PDP1

7.63e-0483246636724073
Cytoband7q11.23

LIMK1 TRIM73 TRIM74

1.30e-04974637q11.23
Cytoband4q13.1

TECRL EPHA5

1.32e-04174624q13.1
CytobandEnsembl 112 genes in cytogenetic band chr7q11

LIMK1 TRIM73 TRIM74

2.56e-03271463chr7q11
GeneFamilyLIM domain containing

LIMK1 LIMK2 WTIP LMO7

2.63e-06593041218
GeneFamilyRing finger proteins

COP1 RNF222 TTC3 TRIM38 TRIM73 TRIM74

5.12e-0627530658
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM38 TRIM73 TRIM74

5.15e-049530359
GeneFamilyPDZ domain containing

LIMK1 LIMK2 LMO7

2.00e-031523031220
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFHX3 ZNF276 ZNF285 CASZ1 ZFP41

6.08e-0371830528
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC3 IFIT2

1.55e-02115302769
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000

PHF6 CORIN ZFHX3 MEGF9 LMO7 EGFL6 ZNF280C EPHA5

7.96e-06492458gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_500

ZFHX3 MEGF9 LMO7 EGFL6 ZNF280C EPHA5

1.36e-05249456gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500

SERTAD4 PHF6 ZFHX3 MEGF9 LMO7 EGFL6 EPHA5

3.06e-05429457gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000

SERTAD4 PHF6 CORIN ZFHX3 MEGF9 LMO7 EGFL6 ZNF280C EPHA5

5.39e-05836459gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000

SERTAD4 PHF6 ZFHX3 MEGF9 TIMP4 LMO7 EGFL6 ZNF280C EPHA5

6.13e-05850459gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000

SERTAD4 ZFHX3 MEGF9 LMO7 EGFL6 EPHA5

1.37e-04377456gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#4_top-relative-expression-ranked_500

PHF6 ZFHX3 MEGF9 EGFL6 EPHA5

1.71e-04247455gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k4
CoexpressionAtlasratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000

CORIN ZFHX3 SCUBE1 BMPER DQX1 TRIM73 ZFP41 RAI1 CGA

1.89e-04986459PCBC_ratio_ECTO_vs_SC_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_500

ZFHX3 MEGF9 LMO7 EGFL6 ZNF280C EPHA5

2.71e-04428456gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SERTAD4 TMEM63B SCUBE1 WTIP LMO7

1.30e-06184465bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

SERTAD4 TMEM63B SCUBE1 WTIP LMO7

1.30e-06184465cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCellPBMC-Mild-Myeloid-Neutrophil-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LIMK2 MEGF9 CBLL2 IFIT2

1.11e-051344647b237690a3765d974f6f813ef2d01154bc23b9d6
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMK1 ZNF276 LRP1B TRIM38

1.25e-05138464c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNFRSF1A MEGF9 IFIT2 TRIM38

2.41e-05163464d005115aa1e1458b51de7eb719794617a4168608
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX3 BMPER LMO7 EPHA5

3.11e-05174464e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX3 BMPER LMO7 EPHA5

3.32e-051774644c069f0d044a96118090b85ca592a21d6b5d9399
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC82 TIMP4 LMO7 IFIT2

3.39e-0517846401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX3 BMPER SHISAL1 EPHA5

3.55e-05180464b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCellAT1_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

TMEM63B SCUBE1 WTIP LMO7

3.55e-05180464ff4728782c3ec814ba071cc22b7894abdd9da837
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

CORIN TECRL LMO7 CASZ1

4.29e-051894649c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LIMK2 TNFRSF1A MEGF9 IFIT2

4.38e-05190464e1c02fe6fa43a36381cb9f02569fa9b1c5f5efdc
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LIMK2 TNFRSF1A MEGF9 IFIT2

4.38e-051904646de15ec88426fbf52acb0a8371f82cf03b6a6237
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

SERTAD4 ZFHX3 RPS27A TTC3

4.47e-05191464509d17d8ee0d028757ce0f2c9b97e5875f06f0ab
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LIMK2 TNFRSF1A MEGF9 IFIT2

4.47e-0519146481f77bf497b8e0ae0affe7d5f4f00446547229f6
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TMEM63B MALRD1 MEGF9 LMO7

4.56e-0519246429f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM63B SCUBE1 WTIP LMO7

4.84e-0519546468f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM63B SCUBE1 WTIP LMO7

4.84e-051954642a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM63B SCUBE1 WTIP LMO7

4.94e-05196464eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMEM63B SCUBE1 WTIP LMO7

4.94e-051964646856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMEM63B SCUBE1 WTIP LMO7

4.94e-051964646731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM63B SCUBE1 WTIP LMO7

5.04e-05197464c9c968e223e7814cd8d22975d849a31b7e0af7aa
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM63B SCUBE1 WTIP LMO7

5.04e-05197464e344455e62b3fe94bb242dc0db58d19a1d3878c7
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM63B SCUBE1 WTIP LMO7

5.04e-05197464734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

RPS27A TTC3 LMO7 TRIM38

5.24e-0519946453ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

SERTAD4 PHF6 RPS27A TTC3

5.34e-05200464ac0e023dbb383bbc46c5cc525431778be8f7ef46
ToppCellmild-Others-Megakaryocytes|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

LIMK2 MEGF9 IFIT2

1.30e-049546374df0149882e2cd0d9aba0ef1ae4aac2cc1aeeac
ToppCellPBMC-Mild-Myeloid-Neutrophil-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LIMK2 CBLL2 IFIT2

2.98e-04126463ec32bfd6cd93fbe02f7577893c82b04d209a52e7
ToppCellPBMC-Mild-Myeloid-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LIMK2 CBLL2 IFIT2

3.34e-04131463fdec4e31ffeb02615ccb7097758a8218dd1f8c1c
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC6A12 MALRD1 EPHA5

3.57e-0413446364979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellCOVID-19_Mild-Myeloid_G-Neutrophil|COVID-19_Mild / Disease group, lineage and cell class

LIMK2 MEGF9 IFIT2

3.65e-04135463e9eb2bebb6d19c439c83f46c12ca0d676db69de8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF276 LRP1B TRIM38

4.96e-04150463afd651c654e715414eff64cf3a37378d057a56a2
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

COP1 IFIT2 ZFP41

5.16e-041524632ff0980dfd8d430cca14649151d856edef115720
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERTAD4 SHISAL1 EGFL6

5.16e-04152463d5ba87b5d34e52cef8475befafea962d70fa8a1d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERTAD4 SHISAL1 EGFL6

5.16e-04152463d88d68a788a3256671ebbc06e104833f1f58f07d
ToppCellnormal_Pleural_Fluid-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

TNFRSF1A WTIP PLEKHM1

5.26e-04153463a156710217ef07c07a80ca6504fa0784d86380fa
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B CASZ1 ZFP41

5.77e-041584637960337d87afecf2692ab65e5991f052ceddfacc
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 SHISAL1 RUBCN

6.21e-04162463c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TECRL LMO7 EGFL6

6.21e-04162463d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TECRL LMO7 EGFL6

6.21e-0416246306f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 SHISAL1 RUBCN

6.21e-04162463f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 SHISAL1 RUBCN

6.21e-041624635d902bb31e691aea9749617cc88303c2448f24b8
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERTAD4 SHISAL1 EGFL6

6.78e-04167463e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SERTAD4 LMO7 CASZ1

6.78e-04167463dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCellControl-Myeloid-MoAM1,_IL1R2|Control / Condition, Lineage and Cell class

TIMP4 IFIT2 CASZ1

6.78e-04167463ab6029ba037b6a499da8758864c44e174cde5587
ToppCellControl-Myeloid-MoAM1,_IL1R2|Myeloid / Condition, Lineage and Cell class

TIMP4 IFIT2 CASZ1

6.78e-041674636e5140527437193f441ca96893b9a00d346614f3
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCUBE1 IFIT2 CASZ1

7.02e-041694634e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZFHX3 IFIT2 TRIM38

7.02e-041694630867528101767fc65e93b3561480bf830c50368d
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

TMEM63B SCUBE1 LMO7

7.14e-041704634cd3b7e43a061948084c01713ae141b5c2c07d89
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

TMEM63B SCUBE1 LMO7

7.14e-0417046336c9f7f98612a72dc511c8da4358d67444f6bcf4
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

SERTAD4 LMO7 CASZ1

7.14e-041704634a19c7e3bb0f9c2601a10debe7000066789b4150
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX3 SCUBE1 EPHA5

7.14e-04170463417b77c12a7982b1ce4b4bc57f30335d261220f5
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 MEGF9 ZFP41

7.64e-041744639d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 MEGF9 ZFP41

7.64e-0417446353cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERTAD4 SHISAL1 EGFL6

7.76e-0417546359249c9e83952d7277010e7be3c779e26399eb5d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MALRD1 LMO7 LRP1B

7.76e-04175463e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

CORIN LRP1B EGFL6

7.76e-04175463fed9e4120c758fdcc23bb248d1801002b0e0d485
ToppCell10x3'2.3-week_17-19-Myeloid_macrophage-stroma-monocytoid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CORIN SLC6A12 RPS27A

7.76e-0417546379fd3e42c91846bda819e878a8eca8415d15ec55
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERTAD4 SHISAL1 EGFL6

7.76e-04175463b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

MALRD1 FUT8 LMO7

7.89e-041764633fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZFHX3 WTIP EGFL6

7.89e-0417646390f36f10c6ed440a0ca549f23219398853f1fbc3
ToppCellwk_08-11-Mesenchymal-Chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SERTAD4 BMPER EGFL6

7.89e-041764631af28b701c4598ce761f85adbd5d79e4918d265a
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP4 LMO7 IFIT2

8.02e-04177463ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP4 LMO7 IFIT2

8.02e-04177463f471f7747d6e8db7546899019af9508f48a14f89
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP4 LMO7 IFIT2

8.02e-04177463cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX3 BMPER SHISAL1

8.16e-04178463431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CORIN SLC6A12 TRIM38

8.16e-04178463c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LIMK2 TNFRSF1A IFIT2

8.16e-0417846394a86f5232fffa6a92a30ea21fb44eec33b4d6c8
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCUBE1 WTIP LMO7

8.29e-04179463d5e3e7f1cd8f683f39a7416f12af7e766dcbead8
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LMO7 CASZ1 RAI1

8.29e-041794636e965e424eebef50f0202cff75f458be395cfca1
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

SERTAD4 TMEM63B LMO7

8.29e-04179463d5763912a4ce7188535675e338799b856edb9dda
ToppCellLV|World / Chamber and Cluster_Paper

CORIN TECRL LMO7

8.42e-041804635ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMPER LMO7 EPHA5

8.56e-0418146308f44323bf71b6004a921bbc969c954c75feeb66
ToppCellP03-Epithelial-alveolar_epithelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM63B LMO7 EGFL6

8.56e-04181463c3dbf8850d3812fbb770798f4cf38908db8bb92b
ToppCellwk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SERTAD4 EGFL6 EPHA5

8.70e-041824630e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCellCOPD-Epithelial-ATI|World / Disease state, Lineage and Cell class

SCUBE1 WTIP LMO7

8.70e-04182463e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

TMEM63B MEGF9 LMO7

8.84e-04183463942530449e9c6583705eeb8f6f12621daea57252
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TMEM63B MEGF9 LMO7

8.84e-041834637b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMPER LRP1B EPHA5

8.98e-041844639cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

SLC6A12 MEGF9 PDP1

8.98e-04184463d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

MALRD1 FUT8 LMO7

9.12e-04185463673f0c688ae6984bc8027df2da335787924f4137
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SERTAD4 FUT8 LRP1B

9.26e-041864632d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCellE17.5-Epithelial-alveolar_epithelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM63B LMO7 EGFL6

9.26e-04186463a7a2ef8392a045a62fa4d0983577711d5d397dc4
ToppCellIPF-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

TMEM63B WTIP LMO7

9.26e-04186463d436ee6cabbde8553ec5e6e55022274090d9f41a
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCUBE1 BMPER TIMP4

9.26e-04186463d3509a579871ba6a8c4edd6137b28f271c9dbe70
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZFHX3 MEGF9 LRP1B

9.26e-0418646323b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellE17.5-Epithelial|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM63B LMO7 EGFL6

9.40e-04187463fdabe716ce67f2eede90548198cbe20bbf693570
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP4 LMO7 IFIT2

9.40e-041874637abc174a06bf07b5f6efe0a370fbb1c23e0079b3
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP4 LMO7 IFIT2

9.40e-04187463b0a2e417b4eb9a185033e89c5df3431c11488688
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MALRD1 LMO7 LRP1B

9.40e-041874637ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMP4 LMO7 IFIT2

9.40e-04187463f9863428943b695f26bd680e6fc5aeb38ec3422f
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TMEM63B LMO7 EGFL6

9.40e-0418746323fe3cdd6cc9b067086a8392d104186d300298ea
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SERTAD4 CBLL2 CASZ1

9.40e-041874633912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCelldroplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEGF9 CCDC82 IFIT2

9.40e-0418746314c239af77116d28d511dea754b6150d20488080
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

TECRL LMO7 CASZ1

9.40e-0418746378cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellControl-Epithelial-ATI|Control / Disease state, Lineage and Cell class

SCUBE1 WTIP LMO7

9.40e-04187463fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

TECRL CASZ1 EPHA5

9.55e-041884636d249fe92d51a19da19ec14bb2262d394255d577
ToppCellILEUM-non-inflamed-(5)_Plasma-(5)_IgG_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FUT8 TTC3 RUBCN

9.55e-041884632156f1bc849ff1cb09ae296d13bedd913ae6b43b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MALRD1 LRP1B CASZ1

9.55e-041884632ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

CORIN TECRL LMO7

9.55e-041884630758b474457efa36488e0195f7357100f4b6a090
DiseaseWilliams-Beuren syndrome (implicated_via_orthology)

LIMK1 LIMK2

2.25e-0415442DOID:1928 (implicated_via_orthology)
Diseaseresting heart rate, chronic obstructive pulmonary disease

FUT8 CASZ1

9.21e-0430442EFO_0000341, EFO_0004351
Diseaselung non-small cell carcinoma (is_implicated_in)

ZFHX3 TNFRSF1A LRP1B

1.18e-03139443DOID:3908 (is_implicated_in)
Diseaseendometrial cancer (is_marker_for)

TNFRSF1A TIMP4

1.25e-0335442DOID:1380 (is_marker_for)
Diseasecervical cancer (is_marker_for)

ZFHX3 TIMP4

1.33e-0336442DOID:4362 (is_marker_for)
DiseaseIschemic stroke

ZFHX3 TECRL FUT8 CASZ1

1.37e-03324444HP_0002140
DiseaseParoxysmal atrial fibrillation

ZFHX3 CASZ1 CGA

1.64e-03156443C0235480
DiseasePersistent atrial fibrillation

ZFHX3 CASZ1 CGA

1.64e-03156443C2585653
Diseasefamilial atrial fibrillation

ZFHX3 CASZ1 CGA

1.64e-03156443C3468561
DiseaseAtrial Fibrillation

ZFHX3 CASZ1 CGA

1.76e-03160443C0004238
Diseasemultiple sclerosis

ZFHX3 LIMK2 TNFRSF1A FUT8 EGFL6

1.85e-03594445MONDO_0005301
DiseaseProstatic Neoplasms

ZFHX3 TIMP4 LRP1B PDP1 CASZ1

2.16e-03616445C0033578
DiseaseMalignant neoplasm of prostate

ZFHX3 TIMP4 LRP1B PDP1 CASZ1

2.16e-03616445C0376358
Diseaselung adenocarcinoma (is_implicated_in)

ZFHX3 LRP1B

2.44e-0349442DOID:3910 (is_implicated_in)
DiseaseAcute Cerebrovascular Accidents

ZFHX3 CASZ1

2.96e-0354442C0751956
Diseasemonocyte count

LIMK1 ZNF276 TNFRSF1A CASZ1 PLEKHM1 EGFL6 RAI1

3.17e-031320447EFO_0005091

Protein segments in the cluster

PeptideGeneStartEntry
CGHSFCYKCIHQSLE

COP1

151

Q8NHY2
QHRCVNTHGSYKCFC

EGFL6

106

Q8IUX8
CVNTFGSYYCKCHIG

EGFL6

191

Q8IUX8
HFHCLFGNCKYVCKT

CASZ1

1181

Q86V15
HYHCTRENCGYKFCG

CASZ1

1456

Q86V15
YYIACKKCNSHAGVC

EPHA5

391

P54756
IPCKHAFCYHCANLY

CBLL2

71

Q8N7E2
TIGCCHKGCLHTYHY

RAI1

1866

Q7Z5J4
CYECKKYHLGLCYGV

PATE2

31

Q6UY27
TGDRCQYYVCHHYCV

LRP1B

4316

Q9NZR2
YALVQHATLYCGKCH

LIMK2

111

P53671
SLGLCYHLHCFKCVA

LMO7

1631

Q8WWI1
YHLHCFKCVACECDL

LMO7

1636

Q8WWI1
YNFDSICRKCQCHGH

MEGF9

391

Q9H1U4
YGTACYCHHKHLCCS

PDP1

21

Q9P0J1
LTHKHVAQLSSYCCY

DQX1

616

Q8TE96
ENHTACHCSTCYYHK

CGA

101

P01215
VCHCLGKSCHLQFYY

MALRD1

341

Q5VYJ5
NCSCQACGLHRYCKY

CCDC82

421

Q8N4S0
CPVHKNCYCESFLAY

BMPER

591

Q8N8U9
IVICLCHVCFGHFKY

TMEM63B

721

Q5T3F8
FHCHTGKCLNYSLVC

CORIN

311

Q9Y5Q5
AYLHCQIGCCYRAKV

IFIT2

281

P09913
YHTCYCLSGLSIAQH

FNTB

361

P49356
YLGKYFCQCCHENAQ

RUBCN

741

Q92622
CLCHRGYILYGTTHC

SCUBE1

346

Q8IWY4
KGCGYGCQLHHVVYC

FUT8

216

Q9BYC5
KLCAFSGLYYCDICH

PLEKHM1

846

Q9Y4G2
CGHSYCHLCITDFFK

TRIM38

31

O00635
YHNNCYKDCIALCFL

SLC6A12

311

P48065
FILCCHHNNTVFKYC

SHISAL1

56

Q3SXP7
FHACCFYQECGGHYL

SERTAD4

186

Q9NUC0
CGHSYCKGCLVSLSY

TRIM74

31

Q86UV6
GCEIKACVKTYHYHC

PHF6

291

Q8IWS0
YECTHCGKAFAYSSC

ZFP41

171

Q8N8Y5
LSCGHVFCHDCLVKY

RNF222

31

A6NCQ9
CKSCHAQFYQCHSLL

ZNF276

136

Q8N554
CCYQKCHGYSKIQIY

TTC3

651

P53804
HYHLNCGCQITTCYT

TIMP4

151

Q99727
YKKLHCIVTYCEYCQ

ZMYM2

671

Q9UBW7
CGHSYCKGCLVSLSY

TRIM73

31

Q86UV7
YHVACYHCEDCGLQL

WTIP

376

A6NIX2
SIYIHCSFCKYNTNC

ZNF280C

636

Q8ND82
ACFCHCIHYIRYLLE

TECRL

186

Q5HYJ1
FDRHYCGKCCLTYCF

RPS27A

136

P62979
SICCTKCHKGTYLYN

TNFRSF1A

56

P19438
CEVCGKCFSYSSYFH

ZNF285

486

Q96NJ3
CYYHCVLCNYSTKAK

ZFHX3

1086

Q15911
LVEHSKLYCGHCYYQ

LIMK1

126

P53667