Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Znf_CHHC	HNRNPF HNRNPH1 HNRNPH2	4.78e-07	3	147	3	IPR012996
Domain	zf-RNPHF	HNRNPF HNRNPH1 HNRNPH2	4.78e-07	3	147	3	PF08080
Pubmed	hnRNPs H, H' and F behave differently with respect to posttranslational cleavage and subcellular localization.	HNRNPF HNRNPH1 HNRNPH2	7.71e-08	3	149	3	10456323
Pubmed	Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissues.	HNRNPF HNRNPH1 HNRNPH2	7.71e-08	3	149	3	14980514
Pubmed	Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.	HNRNPF HNRNPH1 HNRNPH2	7.71e-08	3	149	3	7499401
Pubmed	Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.	GAK SNX17 MXRA8 RMI2 EXT1 BIRC6 HNRNPH2 IGFALS BRD9 ATG9A PSPC1	4.72e-07	359	149	11	35559673
Pubmed	Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins.	LIPE ABHD5 PLIN5	1.53e-06	6	149	3	19717842
Pubmed	Biological insights from 108 schizophrenia-associated genetic loci.	CENPT NAB2 HAPLN4 CHADL PCGF6 CILP2 PLCH2 DGKI CSMD1	6.90e-06	303	149	9	25056061
Pubmed	Expanded CUG repeats Dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex.	HNRNPF HNRNPH1 HNRNPH2	1.24e-05	11	149	3	21900255
Pubmed	A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1.	HNRNPF HNRNPH1 HNRNPH2	1.65e-05	12	149	3	37463454
Pubmed	The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization.	HNRNPF HNRNPH1	1.82e-05	2	149	2	7512260
Pubmed	The RNA-binding proteins hnRNP H and F regulate splicing of a MYC-dependent HRAS exon in prostate cancer cells.	HNRNPF HNRNPH2	1.82e-05	2	149	2	37399401
Pubmed	Non-native proteins inhibit the ER oxidoreductin 1 (Ero1)-protein disulfide-isomerase relay when protein folding capacity is exceeded.	ERO1A PDIA2	1.82e-05	2	149	2	32102847
Pubmed	Functional interactions between Mldp (LSDP5) and Abhd5 in the control of intracellular lipid accumulation.	ABHD5 PLIN5	1.82e-05	2	149	2	19064991
Pubmed	Novel Mutations in Two Saudi Patients with Congenital Retinal Dystrophy.	ALMS1 GUCY2D	1.82e-05	2	149	2	26957854
Pubmed	Mutations in the CACNA1F and NYX genes in British CSNBX families.	CACNA1F NYX	1.82e-05	2	149	2	12552565
Pubmed	The small RNA mascRNA differentially regulates TLR-induced proinflammatory and antiviral responses.	HNRNPF HNRNPH1	1.82e-05	2	149	2	34582376
Pubmed	Ero1alpha is expressed on blood platelets in association with protein-disulfide isomerase and contributes to redox-controlled remodeling of alphaIIbbeta3.	ERO1A PDIA2	1.82e-05	2	149	2	20562109
Pubmed	Post-transcriptional regulation of mu-opioid receptor: role of the RNA-binding proteins heterogeneous nuclear ribonucleoprotein H1 and F.	HNRNPF HNRNPH1	1.82e-05	2	149	2	21739230
Pubmed	Cytochrome P450 1B1 and 2C9 genotypes and risk of ischemic vascular disease, cancer, and chronic obstructive pulmonary disease.	CYP1B1 CYP2C9	1.82e-05	2	149	2	22272893
Pubmed	X-Linked Congenital Stationary Night Blindness	CACNA1F NYX	1.82e-05	2	149	2	20301423
Pubmed	Inhibition of the functional interplay between endoplasmic reticulum (ER) oxidoreduclin-1α (Ero1α) and protein-disulfide isomerase (PDI) by the endocrine disruptor bisphenol A.	ERO1A PDIA2	1.82e-05	2	149	2	25122773
Pubmed	The Ero1alpha-PDI redox cycle regulates retro-translocation of cholera toxin.	ERO1A PDIA2	1.82e-05	2	149	2	20130085
Pubmed	The nob2 mouse, a null mutation in Cacna1f: anatomical and functional abnormalities in the outer retina and their consequences on ganglion cell visual responses.	CACNA1F NYX	1.82e-05	2	149	2	16597347
Pubmed	Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F.	HNRNPF HNRNPH1	1.82e-05	2	149	2	23284676
Pubmed	Functional in vitro analysis of the ERO1 protein and protein-disulfide isomerase pathway.	ERO1A PDIA2	1.82e-05	2	149	2	21757736
Pubmed	Novel mutations in CACNA1F and NYX in Dutch families with X-linked congenital stationary night blindness.	CACNA1F NYX	1.82e-05	2	149	2	15761389
Pubmed	Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip.	CACNA1F NYX ALMS1 GUCY2D C2	3.76e-05	87	149	5	20801516
Pubmed	Tandem immunoprecipitation approach to identify HIV-1 Gag associated host factors.	HNRNPF HNRNPH1 HNRNPH2	4.14e-05	16	149	3	24690621
Pubmed	Defining the membrane proteome of NK cells.	GAK ERO1A LTB4R2 BIRC6 CIT HNRNPF HNRNPH1 HNRNPH2 SLC4A2 SLC7A1 MLF2 WDR11 SLC27A1 DDX3Y ATG9A ZW10	4.42e-05	1168	149	16	19946888
Pubmed	[Genetic variants of CYP1B1 and WDR36 in the patients with primary congenital glaucoma and primary open angle glaucoma from Saint-Petersburg].	CYP1B1 WDR36	5.45e-05	3	149	2	20198978
Pubmed	A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1.	HNRNPF HNRNPH1	5.45e-05	3	149	2	20308327
Pubmed	Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism.	LIPE ABHD5	5.45e-05	3	149	2	17074755
Pubmed	Cellular localization and associations of the major lipolytic proteins in human skeletal muscle at rest and during exercise.	ABHD5 PLIN5	5.45e-05	3	149	2	25054327
Pubmed	Different interaction modes for protein-disulfide isomerase (PDI) as an efficient regulator and a specific substrate of endoplasmic reticulum oxidoreductin-1α (Ero1α).	ERO1A PDIA2	5.45e-05	3	149	2	25258311
Pubmed	Interactions of perilipin-5 (Plin5) with adipose triglyceride lipase.	ABHD5 PLIN5	5.45e-05	3	149	2	21148142
Pubmed	Rab33b and Rab6 are functionally overlapping regulators of Golgi homeostasis and trafficking.	ZW10 RAB33B	5.45e-05	3	149	2	20163571
Pubmed	Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs.	HNRNPF HNRNPH1	5.45e-05	3	149	2	19244236
Pubmed	hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells.	HNRNPF HNRNPH1	5.45e-05	3	149	2	9858532
Pubmed	Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.	LIPE ABHD5	5.45e-05	3	149	2	24440819
Pubmed	Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance.	HNRNPH1 HNRNPH2	5.45e-05	3	149	2	21068389
Pubmed	The CXXCXXC motif determines the folding, structure and stability of human Ero1-Lalpha.	ERO1A PDIA2	5.45e-05	3	149	2	10970843
Pubmed	Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.	HNRNPF HNRNPH1 HNRNPH2 CBX1	5.90e-05	49	149	4	27352031
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	RBM15 CHD1 HNRNPF HNRNPH1 HNRNPH2 MLF2 YLPM1 BRD9 PSPC1	7.49e-05	411	149	9	35182466
Pubmed	Interaction between the human nuclear cap-binding protein complex and hnRNP F.	HNRNPF HNRNPH1	1.09e-04	4	149	2	9111328
Pubmed	Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein.	ABHD5 PLIN5	1.09e-04	4	149	2	21393244
Pubmed	Defective retinal depolarizing bipolar cells in regulators of G protein signaling (RGS) 7 and 11 double null mice.	RGS11 NYX	1.09e-04	4	149	2	22371490
Pubmed	A functional conserved intronic G run in HIV-1 intron 3 is critical to counteract APOBEC3G-mediated host restriction.	HNRNPF HNRNPH1	1.09e-04	4	149	2	25169827
Pubmed	Dynamic retention of Ero1alpha and Ero1beta in the endoplasmic reticulum by interactions with PDI and ERp44.	ERO1A PDIA2	1.09e-04	4	149	2	16677073
Pubmed	Dynamic regulation of Ero1α and peroxiredoxin 4 localization in the secretory pathway.	ERO1A PDIA2	1.09e-04	4	149	2	23979138
Pubmed	Genetic testing for retinal dystrophies and dysfunctions: benefits, dilemmas and solutions.	CACNA1F GUCY2D	1.09e-04	4	149	2	17651254
Pubmed	Regulation of Mcl-1 alternative splicing by hnRNP F, H1 and K in breast cancer cells.	HNRNPF HNRNPH1	1.09e-04	4	149	2	30468106
Pubmed	Combinations of cytochrome P450 gene polymorphisms enhancing the risk for sporadic colorectal cancer related to red meat consumption.	CYP1B1 CYP2C9	1.09e-04	4	149	2	17627011
Pubmed	An intronic G run within HIV-1 intron 2 is critical for splicing regulation of vif mRNA.	HNRNPF HNRNPH1	1.09e-04	4	149	2	23255806
Pubmed	Mutation screening of TRPM1, GRM6, NYX and CACNA1F genes in patients with congenital stationary night blindness.	CACNA1F NYX	1.09e-04	4	149	2	22735794
Pubmed	Analysis of lipolytic protein trafficking and interactions in adipocytes.	LIPE ABHD5	1.09e-04	4	149	2	17189257
Pubmed	Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle.	ABHD5 PLIN5	1.09e-04	4	149	2	26411340
Pubmed	Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated dihydrouridylation.	DUS3L TRMT2A	1.09e-04	4	149	2	34556860
Pubmed	Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility.	DDX3Y KDM6A	1.09e-04	4	149	2	10767340
Pubmed	Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex.	HNRNPF HNRNPH1 HNRNPH2	1.12e-04	22	149	3	18377426
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	RBM15 GAK ERO1A SIPA1 HNRNPF HNRNPH1 PC MAP4K2	1.71e-04	360	149	8	33111431
Pubmed	Hypoxia-inducible factor-2α-dependent hypoxic induction of Wnt10b expression in adipogenic cells.	WNT10B GPAM	1.81e-04	5	149	2	23900840
Pubmed	Conserved oncogenic behavior of the FAM83 family regulates MAPK signaling in human cancer.	FAM83E FAM83D	1.81e-04	5	149	2	24736947
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	WDR36 DUS3L CIT CCNK TRIM3 TRMT2A PC	2.20e-04	281	149	7	24163370
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBM15 CENPT WDR36 CHD1 CCNK HNRNPF HNRNPH1 YLPM1 BRD9 CBX1 DDX3Y PC PSPC1	2.48e-04	954	149	13	36373674
Pubmed	The ER-Localized Protein DFCP1 Modulates ER-Lipid Droplet Contact Formation.	SLC27A1 ZW10	2.70e-04	6	149	2	30970241
Pubmed	Effects of insulin signaling on mouse taste cell proliferation.	SLC2A8 ENTPD2	2.70e-04	6	149	2	31714935
Pubmed	Disulphide production by Ero1α-PDI relay is rapid and effectively regulated.	ERO1A PDIA2	2.70e-04	6	149	2	20802462
Pubmed	Genotype and phenotype of 101 dutch patients with congenital stationary night blindness.	CACNA1F NYX	2.70e-04	6	149	2	23714322
Pubmed	GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.	RGS11 NYX	2.70e-04	6	149	2	24790204
Pubmed	Associations of common variants in genes involved in metabolism and response to exogenous chemicals with risk of multiple myeloma.	CYP1B1 CYP2C9	2.70e-04	6	149	2	19736056
Pubmed	Evidence that dim1 associates with proteins involved in pre-mRNA splicing, and delineation of residues essential for dim1 interactions with hnRNP F and Npw38/PQBP-1.	HNRNPF HNRNPH2	2.70e-04	6	149	2	11054566
Pubmed	Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.	RBM15 WDR36 HNRNPF HNRNPH1 HNRNPH2 PSPC1	2.73e-04	206	149	6	22174317
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MAN2B1 BIRC6 CIT KCNH3 SLC7A1 ZNF263 SH3TC1 PLA2G4B ENTPD2 TMEM132A ATG9A KIFC3 PC CYB5R2	3.00e-04	1105	149	14	35748872
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	CENPT CIT PHKA2 MLF2 FAM83D ZW10	3.02e-04	210	149	6	16565220
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	MAN2B1 ERO1A HNRNPF HNRNPH1 HNRNPH2 SPCS3 CILP2 AFG3L2 DDX3Y TMEM131	3.29e-04	613	149	10	22268729
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	ENPP7 ALKBH7 ERO1A MXRA8 PGLYRP2 ADAMTS13 FGF22 SPCS3 FICD BRD9 SLC49A3 CSMD1 PCSK4	3.37e-04	985	149	13	12975309
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	SNAPIN SNX3 VPS13C SNX17 RILP SLC4A2 TMEM131 ATG9A ZW10	3.42e-04	504	149	9	34432599
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	SNAPIN BIRC6 PHKA2 MLF2 TRMT2A	3.42e-04	139	149	5	25476789
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CACNA1F VPS13C MAGI3 GPAM STOX1 BIRC6 HNRNPF HNRNPH1 LOXHD1 LONRF2 PLXNB3	3.49e-04	736	149	11	29676528
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	MAP1A CHD1 HNRNPH1 TRIM3 MLF2 DDX3Y PC KDM6A MOG RAB33B	3.64e-04	621	149	10	22794259
Pubmed	Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein.	HNRNPF HNRNPH1	3.78e-04	7	149	2	11003644
Pubmed	A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins.	HNRNPH1 HNRNPH2	3.78e-04	7	149	2	31704785
Pubmed	Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.	HNRNPH1 HNRNPH2	3.78e-04	7	149	2	25846207
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RBM15 WDR36 IRF2BP1 CHD1 CIT HNRNPF HNRNPH1 HNRNPH2 MLF2 AFG3L2 YLPM1 CBX1 PSPC1	4.86e-04	1024	149	13	24711643
Pubmed	OTUD1 Activates Caspase-Independent and Caspase-Dependent Apoptosis by Promoting AIF Nuclear Translocation and MCL1 Degradation.	OTUD1 DCAF10	5.02e-04	8	149	2	33898171
Pubmed	Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis.	WNT10B FZD9 KLF1	5.38e-04	37	149	3	18800919
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	CCNK HNRNPF HNRNPH1 YLPM1 PSPC1	5.46e-04	154	149	5	16055720
Pubmed	Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.	CIT SPCS3 WDR11 PC PSPC1	5.79e-04	156	149	5	29961565
Pubmed	A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.	HNRNPF HNRNPH1 HNRNPH2	5.82e-04	38	149	3	18247557
Pubmed	Genetic variations in xenobiotic metabolic pathway genes, personal hair dye use, and risk of non-Hodgkin lymphoma.	CYP1B1 CYP2C9	6.44e-04	9	149	2	19822571
Pubmed	Genetic polymorphisms in cytochrome P450s, GSTs, NATs, alcohol consumption and risk of non-Hodgkin lymphoma.	CYP1B1 CYP2C9	6.44e-04	9	149	2	20131310
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	GAK WDR36 MAP1A CHD1 CCNK HNRNPF HNRNPH1 ALMS1 AFG3L2 YLPM1 CBX1 PC	7.23e-04	934	149	12	33916271
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	RBM15 HNRNPF HNRNPH1 HNRNPH2 TRMT2A AFG3L2 PSPC1	7.75e-04	347	149	7	16033648
Pubmed	Interplay between cell-adhesion molecules governs synaptic wiring of cone photoreceptors.	CACNA1F RGS11	8.02e-04	10	149	2	32879010
Pubmed	Adiponectin and adiponectin receptors in the mouse preimplantation embryo and uterus.	SLC2A8 SLC27A1	8.02e-04	10	149	2	21106494
Pubmed	CEP192 interacts physically and functionally with the K63-deubiquitinase CYLD to promote mitotic spindle assembly.	CYLD ALMS1	8.02e-04	10	149	2	22895009
Pubmed	Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.	CYP1B1 CYP2C9	8.02e-04	10	149	2	12865317
Pubmed	EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex.	LIPE ABHD5	8.02e-04	10	149	2	24196706
Pubmed	Quantitative trait loci for body size components in mice.	DDR1 CAPN10 FZD9 TRMT2A	8.55e-04	98	149	4	16783635
Pubmed	Metabolic gene variants and risk of non-Hodgkin's lymphoma.	CYP1B1 CYP2C9	9.78e-04	11	149	2	16985026
Pubmed	The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms.	FAM83E FAM83D	9.78e-04	11	149	2	29789297
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	MAN2B1 ALKBH7 HAPLN4 PGLYRP2 DUS3L FGF22 CILP2 KLF1 PLIN5 SLC27A1 ACTL9 PCSK4	1.25e-05	797	149	12	chr19p13
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHB5 RILP SSC5D GPR153 PDIA2 DDX3Y IRGC	1.74e-06	170	149	7	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	CACNA1F VPS13C FAM83E MAGI3 PHKA2 PLA2G4B KIFC3	5.08e-06	200	149	7	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	COVID-19-Heart-Adipocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HS3ST5 GPAM LIPE PLIN5 PC CDH15	1.29e-05	153	149	6	93958bd9c951222ba5b740d1cb83fd5d78a10e1e
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDR1 RGS11 TG ALMS1 FAM83D ZW10	2.50e-05	172	149	6	b043d4f81dced7fb3326043f68474123be47cc5d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_endothelial_cell_-_unspecif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CYP2C9 MAP1A HS3ST5 ARHGEF25 FZD9 PRXL2C	2.67e-05	174	149	6	4d8c4a7d8f4972da68cebe0a79eb1a14ec546121
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	INHBB MXRA8 SLC7A1 LIPE TMEM131 PC	2.75e-05	175	149	6	2812ac2ef41d245db544697fb6da1883361c96e8
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYP1B1 FZD9 APOLD1 PLIN5 MAP4K2 PLXNB3	2.94e-05	177	149	6	b1775e05c28883a15c56628028770bc59d3233fb
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Deptor_(Deep_layer_pyramidal_cells--Layer_5a)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MARCHF10 ADAMTS13 GRM2 LOXHD1 IRGC	3.15e-05	108	149	5	514dfc3f7ac303311ae599f981f3f3c7eb6801b8
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1F DDR1 HS3ST5 MAGI3 PLA2G4B KIFC3	3.33e-05	181	149	6	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MXRA8 IL17D SSC5D CILP2 ENTPD2 SHISA3	3.54e-05	183	149	6	2beb5414958d38a5341870d55229f3b1707e76bf
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 MXRA8 ARHGEF25 ENTPD2 C2 SHISA3	3.76e-05	185	149	6	eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 MXRA8 ARHGEF25 ENTPD2 C2 SHISA3	3.76e-05	185	149	6	f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 MXRA8 ARHGEF25 ENTPD2 C2 SHISA3	3.76e-05	185	149	6	ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	VPS13C CHD1 BIRC6 HNRNPH1 TMEM131 KDM6A	4.11e-05	188	149	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	SSC5D CILP2 DHH SH3TC1 ZFP36L1 PLA2G4B	4.11e-05	188	149	6	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 VPS13C CHD1 ENTPD2 DDX3Y CDH15	4.49e-05	191	149	6	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 MXRA8 GPR153 ENTPD2 CSMD1 SHISA3	4.62e-05	192	149	6	853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 MXRA8 ARHGEF25 GPR153 ENTPD2 SHISA3	4.62e-05	192	149	6	d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1B1 MXRA8 GPR153 ENTPD2 C2 SHISA3	4.62e-05	192	149	6	f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 MXRA8 GPR153 ENTPD2 CSMD1 SHISA3	4.62e-05	192	149	6	49281626ecad0456fdbded2378b7028d7b589686
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	CYP1B1 MAP1A PCDHB5 SNED1 SSC5D CILP2	4.76e-05	193	149	6	194e7fa00a50cc4e026987b715323d125d79594e
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCDHB5 MXRA8 ARHGEF25 GPR153 C2 FOXF2	4.90e-05	194	149	6	7826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 MXRA8 CILP2 ZFP36L1 DDX3Y C2	5.18e-05	196	149	6	61bee32ca299219f31a30b57124e44e85b798e9f
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PCDHB5 FAM83E PHKA2 CAMKK2 ENTPD2 DGKI	5.48e-05	198	149	6	62059185afdf66126a6fbc899ce611c47e7a0feb
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DDR1 SLC2A8 FAM229A ENTPD2 DGKI ZW10	5.48e-05	198	149	6	dd0465b45b02cb8edf0914d19afb52fcaaeb012c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	FAM83E ADAMTS13 SH3TC1 C2 MAP4K2 FOXF2	5.80e-05	200	149	6	aafe594c88710f8c53d59667cdac5035e08f5511
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	FAM83E ADAMTS13 SH3TC1 C2 MAP4K2 FOXF2	5.80e-05	200	149	6	a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IRF2BP1 TTLL5 EXT1 ARHGEF25 CYB5R2 FOXF2	5.80e-05	200	149	6	a372ef3f9e6ff6e3c3376d6e10182977c5067788
Disease	X-linked congenital stationary night blindness	CACNA1F NYX	2.33e-05	2	143	2	cv:CN043584
Disease	congenital stationary night blindness (implicated_via_orthology)	CACNA1F NYX	2.33e-05	2	143	2	DOID:0050534 (implicated_via_orthology)
Disease	Night blindness, congenital stationary	CACNA1F NYX GRK1	7.21e-05	17	143	3	C0339535
Disease	Congenital stationary night blindness	CACNA1F NYX	1.39e-04	4	143	2	cv:C0339535
Disease	congenital stationary night blindness (is_implicated_in)	CACNA1F GUCY2D	1.39e-04	4	143	2	DOID:0050534 (is_implicated_in)
Disease	Prostatic Neoplasms	CYP1B1 DDR1 WNT10B CHD1 SSR2 HNRNPH1 SLC4A2 SLC7A1 CAMKK2 CBX1 KDM6A	2.16e-04	616	143	11	C0033578
Disease	Malignant neoplasm of prostate	CYP1B1 DDR1 WNT10B CHD1 SSR2 HNRNPH1 SLC4A2 SLC7A1 CAMKK2 CBX1 KDM6A	2.16e-04	616	143	11	C0376358
Disease	night blindness (is_implicated_in)	NYX GRK1	3.45e-04	6	143	2	DOID:8499 (is_implicated_in)
Disease	glucose intolerance (biomarker_via_orthology)	PLEKHS1 SLC27A1	3.45e-04	6	143	2	DOID:10603 (biomarker_via_orthology)
Disease	suicidal ideation	WDR36 OSM SHISA3	3.71e-04	29	143	3	EFO_0004320
Disease	Cone-Rod Dystrophy 2	CACNA1F TTLL5 GUCY2D	3.71e-04	29	143	3	C3489532
Disease	Disorder of eye	CYP1B1 CACNA1F NYX ALMS1 GUCY2D CLRN1	6.05e-04	212	143	6	C0015397
Disease	X-11787 measurement	CYP2C9 ALMS1	6.41e-04	8	143	2	EFO_0021258
Disease	fish oil supplement exposure measurement, triglyceride measurement	MAP1A HAPLN4	1.02e-03	10	143	2	EFO_0004530, EFO_0600007
Disease	Night blindness, congenital stationary, type 1	CACNA1F NYX	1.49e-03	12	143	2	C3501847
Disease	Night Blindness, Congenital Stationary, Type 1A	CACNA1F NYX	1.49e-03	12	143	2	C3495587
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)	CACNA1F NYX	1.49e-03	12	143	2	C1864877
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B	CACNA1F NYX	1.49e-03	12	143	2	C1850362
Disease	X-Linked Csnb	CACNA1F NYX	1.49e-03	12	143	2	C3711543
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A	CACNA1F NYX	1.49e-03	12	143	2	C1848172
Disease	leprosy	CYLD RMI2 MAGI3 EXT1	1.61e-03	103	143	4	EFO_0001054
Disease	Cone-rod synaptic disorder, congenital nonprogressive	CACNA1F NYX	1.76e-03	13	143	2	C4041558
Disease	coffee consumption measurement	SNX17 BIRC6 FZD9 CBX1 C2	1.98e-03	182	143	5	EFO_0006781
Disease	cardiotoxicity, response to anthracycline-based chemotherapy	FGF22 SHISA3	2.04e-03	14	143	2	EFO_0005257, EFO_1001482
Disease	Schizophrenia	CACNA1F DDR1 AHI1-DT GRM2 CAMKK2 TRMT2A WDR11 PLA2G4B GPR153 CSMD1 MOG	3.91e-03	883	143	11	C0036341
Disease	Benign Neoplasm	PLEKHS1 BIRC6 KDM6A	4.44e-03	68	143	3	C0086692
Disease	Neoplasms	PLEKHS1 BIRC6 KDM6A	4.44e-03	68	143	3	C0027651
Disease	breast size	INHBB VPS13C SNX17	4.62e-03	69	143	3	EFO_0004884

Protein segments in the cluster

Peptide	Gene	Start	Entry
RRFPIEAGDSRGLAA	FAM229A	61	H3BQW9
FFPGRIRRVIGDFGV	SLC4A2	926	P04920
PESLRGRDRIVFGNI	ARHGEF25	196	Q86VW2
GARRFVTLDFGRPIL	BIRC6	1786	Q9NR09
GIPINGRRFGDRFLL	CSMD1	701	Q96PZ7
AADEARDRINRFLPG	BRD9	306	Q9H8M2
FVGVGPARVRDLFAL	AFG3L2	381	Q9Y4W6
ARAVSVPLGGRVARF	DDR1	331	Q08345
FGGAREGAQRPRFIS	GRM2	661	Q14416
GREAGRDLLRPFVRA	ALMS1	4021	Q8TCU4
LFTGFEGRFRAELLR	ACTL9	346	Q8TC94
REGARFIFDVGTRLG	CCNK	51	O75909
PDAAFRGLGSLRELV	IGFALS	186	P35858
DAPGEFLLRVFSTGR	CAPN10	476	Q9HC96
ALRPQAGASFRELRG	AHI1-DT	161	P0C7V0
ADLGPRCVLFETFGR	DUS3L	156	Q96G46
FGGPLERLDAIARDA	CHD1	1141	O14646
RLFEDSSRGRLPAGA	CIT	1996	O14578
GAELLRDPSLGAQFR	ADAMTS13	111	Q76LX8
GSGDERVAFVNFRRP	RBM15	211	Q96T37
VPLAALAREFDRFGT	RBM15	466	Q96T37
GRFPDRTEATIGVDF	RAB33B	56	Q9H082
IGETIFFRGPRGRLF	CYB5R2	111	Q6BCY4
FEFRVGATDRGSPAL	PCDHB5	526	Q9Y5E4
GFSFRELLEDPVGRA	RGS11	301	O94810
DLARRFGPEAAAGLV	RILP	41	Q96NA2
GELGRAERLPVLFLF	PCDHGB4	6	Q9UN71
PEFAPRFSRGLRGEL	KCNH3	686	Q9ULD8
DPRDRFELLQRVGAG	MAP4K2	11	Q12851
IVFFGSRGFLIPRRA	APOLD1	201	Q96LR9
EGLGLFARDPRFVAL	CACNA1F	1906	O60840
GLDATREGPDRNFRL	OTUD1	181	Q5VV17
VTPRSREAFGGRELG	MAP1A	691	P78559
GAERGEFPYLGRLRE	MAGI3	36	Q5TCQ9
LLGRAEPEFAGGRRE	GGNBP2	271	Q9H3C7
DPALERRGTLAGDVF	GUCY2D	716	Q02846
RDFRLLRVGFEAGGL	MTMR11	136	A4FU01
RIFRSFPRGDAGEVT	NAB2	251	Q15742
KGESGGAVFLERRFR	C2	676	P06681
FRRPEELGRVDGDFL	INHBB	61	P09529
RVLGYVDPVEAGRFR	FICD	296	Q9BVA6
REALGGLDSRLFGFV	KDM6A	46	O15550
RTPAAGGFFRRSLLL	JPH4	211	Q96JJ6
PRGKRGFSRGSVEEF	LOXHD1	1461	Q8IVV2
PFDFRGARILSGQEE	ENTPD2	151	Q9Y5L3
DTANDGFVRLRGLPF	HNRNPH2	106	P55795
RLGGARTQAEFPLRA	HS3ST5	46	Q8IZT8
RTVDGPGILTREAFR	PCSK4	266	Q6UW60
EPSASFRGGGRLIRV	PLXNB3	1021	Q9ULL4
AGVARDPGFRSNFRR	PGLYRP2	306	Q96PD5
SLGRGLFVDPARDNF	DCAF10	131	Q5QP82
AGGPEAFAAFLRRER	FAM83D	41	Q9H4H8
AGPERRRASLLAFAE	GPR153	431	Q6NV75
TGLFGEEDVRFRSAP	IL17D	121	Q8TAD2
FFLRVDPGGRVQGTR	FGF22	51	Q9HCT0
FRGAARLGALRPEEL	LONRF2	81	Q1L5Z9
RELLAGFGEAAPRFR	PDIA2	291	Q13087
LFDAGTLRAGEFRRE	PLA2G4B	96	P0C869
DTANDGFVRLRGLPF	HNRNPH1	106	P31943
GELGRAERLPVLFLF	PCDHGB5	6	Q9Y5G0
FRGLDARALQPSEGR	LBX2	56	Q6XYB7
TLRIRNVRFSDEGGF	MOG	111	Q16653
RVARAFERGIPVFGT	IRGC	356	Q6NXR0
AALEIGRFDPERGRG	FZD9	21	O00144
IGAREERGVRAPSFA	GAK	1156	O14976
VRPALRARAPDAFVG	KLF1	136	Q13351
GLRFETRARTLGRFP	KCNA7	21	Q96RP8
VPRGRRLGSFRFLEA	EXT1	336	Q16394
FREGGSRSPRENFVR	DGKI	236	O75912
GPAEGRVARGSERFR	DHH	61	O43323
RFRLPGLGEAVFFTR	ATG9A	231	Q7Z3C6
PPARRAVDVGAFLRD	CENPT	211	Q96BT3
RGFARGLEPERIIGA	CBX1	111	P83916
QRFDGILTEGEGPRR	ERO1A	286	Q96HE7
VGGPRKASFRFRDED	MARCHF10	261	Q8NA82
LRFLEDTFGNDGRPR	MAN2B1	176	O00754
IRKRSFGNPFEGSRR	CAMKK2	491	Q96RR4
FGNPFEGSRREERSL	CAMKK2	496	Q96RR4
VRSLGFPDATRRLFG	HAPLN4	346	Q86UW8
DRPAFASFRVVSGGR	CYP1B1	116	Q16678
GRGIFPLAERANRGF	CYP2C9	96	P11712
RALRDGAFQPVGRSL	CHADL	606	Q6NUI6
RSGEEKFPGVVRFRG	CYLD	136	Q9NQC7
IGNRERPGFGRFERS	DDX3Y	106	O15523
FRAVGPSFRAGLEVE	ENPP7	366	Q6UWV6
IAARGPFRARGEKVE	GRK1	386	Q15835
DRFRLRAFALDLGGS	CDH15	116	P55291
AFRVRSLPLGREGFG	INAVA	611	Q3KP66
GLVGRVFAFDATARP	IRF2BP1	251	Q8IU81
GFLAAGEIDPLNRRF	PHKA2	416	P46019
FTSGRFAIDPELRGA	LIPE	511	Q05469
QRPLEFRRLESSGAG	MLF2	206	Q15773
PERSLGRFRGRFEDE	PCGF6	66	Q9BYE7
FLGERAFGTLPSLRR	NYX	76	Q9GZU5
AFDNLFRRVPGALRG	NYX	166	Q9GZU5
EFMFEEGSFRRRPRG	FOXF2	181	Q12947
DSANDGFVRLRGLPF	HNRNPF	106	P52597
GRDLFAEGLLEFLRP	SNAPIN	21	O95295
FSDVRRFLGRFGLQP	TRMT2A	86	Q8IZ69
EARLRDPSGDFSVRG	RMI2	71	Q96E14
PRLGAFFLERSAGAE	GINS3	41	Q9BRX5
AGGRRKRVEFVTFAP	TMEM132A	956	Q24JP5
ARADRETRLFGGPRA	TMEM191B	261	P0C7N4
RRRFGGDATFKLQEP	FAM83E	446	Q2M2I3
PRFLTRLFEGSGEAR	LTB4R2	301	Q9NPC1
FAERVRSVELGPGLR	KIFC3	761	Q9BVG8
PRGRRVFLAAFAAAL	SLC2A8	21	Q9NY64
LGGFFIRRRLDETPD	GPAM	271	Q9HCL2
GPRERSDLGFITFDI	SPCS3	56	P61009
VERFTFAETAGLRPG	SIPA1	711	Q96FS4
TGGSIRRFSFARAEP	SHISA3	171	A0PJX4
RLFSRLPLGECGRDF	SH3TC1	931	Q8TE82
ESGLFRVRLADGPNR	SSC5D	766	A1L4H1
FPSEETLRGLGRRGF	OSM	81	P13725
FSELVDGRGRVSARF	SNED1	1246	Q8TER0
AFDLLGFGRSSRPRF	ABHD5	106	Q8WTS1
RDEESFFGERRIPRG	ALKBH7	181	Q9BT30
RGRVVAADSGEPLRF	CILP2	476	Q8IUL8
LGELVLPSGAFRRAD	CILP2	581	Q8IUL8
VRQCGLGARPFRFSF	CLRN1	71	P58418
DARGQRVPFGALFRE	PRXL2C	41	Q7RTV5
PGRLAGRVQASRFID	SLC49A3	531	Q6UXD7
FGEGTELRDRAPGFR	PLEKHS1	401	Q5SXH7
SPGRGRGEVRLELAF	SNX17	336	Q15036
GGILAQREFDRRFSP	SSR2	131	P43308
FRDRSFSEGGERLLP	ZFP36L1	86	Q07352
VGGRDFLRPLVFFPE	STAG3	816	Q9UJ98
AASIFREEGPRGLFR	SLC25A45	151	Q8N413
DRGFGFIRLESRTLA	PSPC1	116	Q8WXF1
REGFDPRQTSDRLFF	SLC27A1	606	Q6PCB7
FDELIGRPIGEFSRT	SLC7A1	136	P30825
PFAKGFRDTGRNRGV	TBX22	276	Q9Y458
RRGFPELVLGTRDTG	PLCH2	941	O75038
PGGRAVFRAFRRANA	STOX1	31	Q6ZVD7
GRPFDLRRIVGISSE	TMEM131	1166	Q92545
LSRQPRDFGDSLARG	VPS13C	3506	Q709C8
AFLRQLPFRGDDGIF	SNX3	96	O60493
RFDGPRRFEDLGSRC	YLPM1	761	P49750
FRDVPAAALAEGRGR	PLIN5	336	Q00G26
PEFRAVGAALRERLG	WNT10B	266	O00744
DLPTGRSIAFRGERG	WDR11	551	Q9BZH6
ERELDGPKQIFFGRR	ZNF396	131	Q96N95
RGFGGDPRRVSLAAD	TG	2371	P01266
FRDILLREGPEGFAR	PC	541	P11498
VSRAEARRGFGLDGL	ZNF584	86	Q8IVC4
NDRRGGFIRIFPTSE	TTLL5	476	Q6EMB2
SRGPSDLRFRGEAGL	ZNF487	11	B1APH4
EGQFKFRFGVRGRSP	TRIM3	516	O75382
TATFVDLVPGFRRLG	ZW10	571	O43264
IFDGPTGEGRLLRFR	WDR36	361	Q8NI36
RFRFQEAAGPREALS	ZNF263	46	O14978
FRSLFAAGRPERGPA	KLHL35	66	Q6PF15
PLFLRDRVAVGADAF	MXRA8	236	Q9BRK3