Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	alpha-tocopherol omega-hydroxylase activity	CYP4F8 CYP4F12	1.42e-04	5	76	2	GO:0052871
GeneOntologyMolecularFunction	leukotriene-B4 20-monooxygenase activity	CYP4F8 CYP4F12	2.97e-04	7	76	2	GO:0050051
GeneOntologyMolecularFunction	alkane 1-monooxygenase activity	CYP4F8 CYP4F12	2.97e-04	7	76	2	GO:0018685
GeneOntologyMolecularFunction	arachidonate omega-hydroxylase activity	CYP4F8 CYP4F12	6.31e-04	10	76	2	GO:0052869
GeneOntologyMolecularFunction	fatty acid omega-hydroxylase activity	CYP4F8 CYP4F12	6.31e-04	10	76	2	GO:0120250
GeneOntologyMolecularFunction	long-chain fatty acid omega-hydroxylase activity	CYP4F8 CYP4F12	6.31e-04	10	76	2	GO:0102033
GeneOntologyMolecularFunction	transporter activity	CNNM4 ATG9B ABCA3 CYBRD1 SLC13A1 TMEM165 LRRC26 TMC8 KCNK16 ADAMTS8 SLC2A1 SLC2A4 SLC4A11	1.07e-03	1289	76	13	GO:0005215
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	CYP4F8 CYP4F12	1.09e-03	13	76	2	GO:0016713
GeneOntologyMolecularFunction	arachidonate binding	CYP4F8 CYP4F12	1.45e-03	15	76	2	GO:0050544
GeneOntologyMolecularFunction	transmembrane transporter activity	CNNM4 ABCA3 CYBRD1 SLC13A1 TMEM165 LRRC26 TMC8 KCNK16 ADAMTS8 SLC2A1 SLC2A4 SLC4A11	1.59e-03	1180	76	12	GO:0022857
GeneOntologyMolecularFunction	icosanoid binding	CYP4F8 CYP4F12	1.66e-03	16	76	2	GO:0050542
GeneOntologyMolecularFunction	icosatetraenoic acid binding	CYP4F8 CYP4F12	1.66e-03	16	76	2	GO:0050543
GeneOntologyMolecularFunction	metalloendopeptidase inhibitor activity	TIMP1 TIMP4	1.66e-03	16	76	2	GO:0008191
GeneOntologyBiologicalProcess	carbohydrate derivative biosynthetic process	TGFB1 VANGL2 POGLUT1 PPT2 TM9SF2 AP2A1 ST8SIA6 TMEM165 PTH2 POFUT1 HAS1 SLC2A4	1.71e-05	736	77	12	GO:1901137
GeneOntologyBiologicalProcess	hyaluronan biosynthetic process	TGFB1 AP2A1 HAS1	2.71e-05	16	77	3	GO:0030213
GeneOntologyBiologicalProcess	negative regulation of hyaluronan biosynthetic process	TGFB1 AP2A1	8.21e-05	4	77	2	GO:1900126
GeneOntologyBiologicalProcess	membrane protein proteolysis	TGFB1 TIMP1 TIMP4 SPPL2C	9.62e-05	64	77	4	GO:0033619
GeneOntologyBiologicalProcess	cell recognition	ZP1 PRTG TEX101 CRTAC1 SPPL2C AMIGO1	9.76e-05	198	77	6	GO:0008037
GeneOntologyBiologicalProcess	cellular response to osmotic stress	EPO SLC2A1 SLC2A4 SLC4A11	1.52e-04	72	77	4	GO:0071470
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	PRTG SCARF2 NECTIN2 MDGA2 CDHR5 PLXNB3 AMIGO1	1.68e-04	313	77	7	GO:0098742
GeneOntologyBiologicalProcess	polysaccharide biosynthetic process	TGFB1 AP2A1 ESRRB HAS1	1.88e-04	76	77	4	GO:0000271
GeneOntologyBiologicalProcess	leukotriene B4 catabolic process	CYP4F8 CYP4F12	2.04e-04	6	77	2	GO:0036101
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	TGFB1 CNNM4 CYBRD1 TMEM165 TEX101 TMC8 STEAP3 CYP4F12 SPPL2C SLC4A11	2.84e-04	705	77	10	GO:0055080
GeneOntologyBiologicalProcess	leukotriene B4 metabolic process	CYP4F8 CYP4F12	2.85e-04	7	77	2	GO:0036102
GeneOntologyBiologicalProcess	metal ion transport	TGFB1 EPO CNNM4 CYBRD1 SLC13A1 TMEM165 LRRC26 STEAP3 KCNK16 SLC4A11 AMIGO1 PCSK9	3.15e-04	1000	77	12	GO:0030001
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	TGFB1 CNNM4 CYBRD1 TMEM165 TEX101 TMC8 STEAP3 CYP4F12 SPPL2C SLC4A11	3.24e-04	717	77	10	GO:0050801
GeneOntologyBiologicalProcess	multicellular organismal-level chemical homeostasis	TGFB1 ABCA3 CYBRD1 CYP4F12	3.60e-04	90	77	4	GO:0140962
GeneOntologyBiologicalProcess	leukotriene catabolic process	CYP4F8 CYP4F12	3.80e-04	8	77	2	GO:0036100
GeneOntologyBiologicalProcess	negative regulation of membrane protein ectodomain proteolysis	TIMP1 TIMP4	3.80e-04	8	77	2	GO:0051045
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	TGFB1 CNNM4 CYBRD1 TMEM165 TEX101 TMC8 STEAP3 SPPL2C SLC4A11	4.44e-04	611	77	9	GO:0030003
GeneOntologyBiologicalProcess	hyaluronan metabolic process	TGFB1 AP2A1 HAS1	4.47e-04	40	77	3	GO:0030212
GeneOntologyBiologicalProcess	multicellular organismal-level homeostasis	TGFB1 EPO FLT3LG ABCA3 PIANP CYBRD1 ACHE ESRRB CYP4F12 MERTK PTGS1 SLC2A1	4.61e-04	1043	77	12	GO:0048871
GeneOntologyBiologicalProcess	connective tissue replacement involved in inflammatory response wound healing	TGFB1 TIMP1	4.87e-04	9	77	2	GO:0002248
GeneOntologyBiologicalProcess	dehydroascorbic acid transport	SLC2A1 SLC2A4	4.87e-04	9	77	2	GO:0070837
GeneOntologyBiologicalProcess	regulation of hyaluronan biosynthetic process	TGFB1 AP2A1	4.87e-04	9	77	2	GO:1900125
GeneOntologyBiologicalProcess	inorganic ion homeostasis	TGFB1 CNNM4 CYBRD1 TMEM165 TEX101 TMC8 STEAP3 CYP4F12 SPPL2C	5.05e-04	622	77	9	GO:0098771
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	TGFB1 CNNM4 CYBRD1 TMEM165 TEX101 TMC8 STEAP3 SPPL2C SLC4A11	5.05e-04	622	77	9	GO:0006873
GeneOntologyCellularComponent	endoplasmic reticulum lumen	QSOX1 SUMF2 POGLUT1 TIMP1 ACHE PDIA2 DNAJC1 PCSK9	3.02e-05	332	77	8	GO:0005788
GeneOntologyCellularComponent	endolysosome membrane	AP2A1 AP2A2 PCSK9	5.24e-05	20	77	3	GO:0036020
GeneOntologyCellularComponent	apical plasma membrane	VANGL2 CYP4F8 CYBRD1 AP2A1 SLC13A1 CDHR5 CYP4F12 SLC2A1 SLC4A11	7.44e-05	487	77	9	GO:0016324
GeneOntologyCellularComponent	side of membrane	FLT3LG EFNA1 AP2A1 AP2A2 ACHE TEX101 GAS1 MDGA2 IL2RB SPPL2C SLC2A4 PCSK9	8.04e-05	875	77	12	GO:0098552
GeneOntologyCellularComponent	vacuole	GLMP USP6 ATG9B ABCA3 CYBRD1 PPT2 AP2A1 AP2A2 SFTPB TMEM165 SPPL2C PCSK9	1.20e-04	913	77	12	GO:0005773
GeneOntologyCellularComponent	lysosome	GLMP USP6 ABCA3 CYBRD1 PPT2 AP2A1 AP2A2 SFTPB TMEM165 SPPL2C PCSK9	1.81e-04	811	77	11	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	GLMP USP6 ABCA3 CYBRD1 PPT2 AP2A1 AP2A2 SFTPB TMEM165 SPPL2C PCSK9	1.81e-04	811	77	11	GO:0000323
GeneOntologyCellularComponent	endolysosome	AP2A1 AP2A2 PCSK9	1.82e-04	30	77	3	GO:0036019
GeneOntologyCellularComponent	clathrin-coated pit	AP2A1 AP2A2 CDHR5 SLC2A4	2.18e-04	80	77	4	GO:0005905
GeneOntologyCellularComponent	lysosomal membrane	GLMP ABCA3 CYBRD1 AP2A1 AP2A2 TMEM165 SPPL2C PCSK9	2.97e-04	462	77	8	GO:0005765
GeneOntologyCellularComponent	lytic vacuole membrane	GLMP ABCA3 CYBRD1 AP2A1 AP2A2 TMEM165 SPPL2C PCSK9	2.97e-04	462	77	8	GO:0098852
GeneOntologyCellularComponent	endosome	TMUB1 USP6 ATG9B ABCA3 TM9SF2 AP2A1 AP2A2 SFTPB TMEM165 STEAP3 IL2RB SLC2A4 PCSK9	3.13e-04	1167	77	13	GO:0005768
GeneOntologyCellularComponent	multivesicular body	ABCA3 SFTPB STEAP3 SLC2A4	3.14e-04	88	77	4	GO:0005771
GeneOntologyCellularComponent	apical part of cell	VANGL2 CYP4F8 CYBRD1 AP2A1 SLC13A1 CDHR5 CYP4F12 SLC2A1 SLC4A11	3.21e-04	592	77	9	GO:0045177
GeneOntologyCellularComponent	vacuolar membrane	GLMP ABCA3 CYBRD1 AP2A1 AP2A2 TMEM165 SPPL2C PCSK9	5.50e-04	507	77	8	GO:0005774
GeneOntologyCellularComponent	alveolar lamellar body	ABCA3 SFTPB	5.91e-04	10	77	2	GO:0097208
GeneOntologyCellularComponent	cell surface	TGFB1 EPO FLT3LG SCUBE2 ACHE TEX101 NECTIN2 IL2RB ADGRA2 SLC2A4 PLXNB3 PCSK9	7.17e-04	1111	77	12	GO:0009986
GeneOntologyCellularComponent	basolateral plasma membrane	VANGL2 CNNM4 PIANP AP2A1 SLC2A1 SLC4A11	1.17e-03	320	77	6	GO:0016323
GeneOntologyCellularComponent	AP-2 adaptor complex	AP2A1 AP2A2	1.18e-03	14	77	2	GO:0030122
GeneOntologyCellularComponent	clathrin coat of endocytic vesicle	AP2A1 AP2A2	1.36e-03	15	77	2	GO:0030128
GeneOntologyCellularComponent	endosome membrane	ATG9B ABCA3 TM9SF2 AP2A1 AP2A2 TMEM165 STEAP3 PCSK9	1.66e-03	602	77	8	GO:0010008
GeneOntologyCellularComponent	platelet alpha granule lumen	TGFB1 QSOX1 TIMP1	1.94e-03	67	77	3	GO:0031093
GeneOntologyCellularComponent	basal plasma membrane	VANGL2 CNNM4 PIANP AP2A1 SLC2A1 SLC4A11	1.95e-03	354	77	6	GO:0009925
GeneOntologyCellularComponent	coated vesicle	VANGL2 AP2A1 AP2A2 SFTPB SLC2A4 PCSK9	2.12e-03	360	77	6	GO:0030135
GeneOntologyCellularComponent	clathrin coat of coated pit	AP2A1 AP2A2	2.69e-03	21	77	2	GO:0030132
GeneOntologyCellularComponent	lamellar body	ABCA3 SFTPB	2.69e-03	21	77	2	GO:0042599
GeneOntologyCellularComponent	basal part of cell	VANGL2 CNNM4 PIANP AP2A1 SLC2A1 SLC4A11	2.71e-03	378	77	6	GO:0045178
GeneOntologyCellularComponent	extracellular matrix	TGFB1 ZP1 LRIG1 TIMP1 SFTPB TIMP4 ACHE ADAMTS8	2.82e-03	656	77	8	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	TGFB1 ZP1 LRIG1 TIMP1 SFTPB TIMP4 ACHE ADAMTS8	2.88e-03	658	77	8	GO:0030312
GeneOntologyCellularComponent	vesicle membrane	ATG9B ABCA3 TM9SF2 AP2A1 AP2A2 TMEM165 TEX101 STEAP3 SPPL2C SLC2A4 SLC4A11 PCSK9	3.19e-03	1325	77	12	GO:0012506
GeneOntologyCellularComponent	platelet alpha granule	TGFB1 QSOX1 TIMP1	4.92e-03	93	77	3	GO:0031091
GeneOntologyCellularComponent	clathrin adaptor complex	AP2A1 AP2A2	5.81e-03	31	77	2	GO:0030131
GeneOntologyCellularComponent	clathrin-coated endocytic vesicle	AP2A1 AP2A2 SFTPB	6.18e-03	101	77	3	GO:0045334
GeneOntologyCellularComponent	endoplasmic reticulum membrane	ATG9B CYP4F8 SFTPB AGPAT1 TMC8 TM7SF2 CYP4F12 TMEM214 DNAJC1 SPPL2C PTGS1	7.56e-03	1293	77	11	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	ATG9B CYP4F8 SFTPB AGPAT1 TMC8 TM7SF2 CYP4F12 TMEM214 DNAJC1 SPPL2C PTGS1	7.82e-03	1299	77	11	GO:0098827
HumanPheno	Interstitial pneumonitis	ABCA3 SFTPB IL2RB	3.96e-05	17	21	3	HP:0006515
HumanPheno	Abnormal bronchoalveolar fluid protein level	ABCA3 SFTPB	4.84e-05	3	21	2	HP:0032975
HumanPheno	Desquamative interstitial pneumonitis	ABCA3 SFTPB	9.67e-05	4	21	2	HP:0005942
HumanPheno	Progressive reticulate hyperpigmentation	POGLUT1 POFUT1	9.67e-05	4	21	2	HP:0007456
HumanPheno	Scrotal hyperpigmentation	POGLUT1 POFUT1	9.67e-05	4	21	2	HP:0012855
HumanPheno	Nasal flaring	ABCA3 SFTPB	9.67e-05	4	21	2	HP:0030863
HumanPheno	Anal margin squamous cell carcinoma	POGLUT1 POFUT1	9.67e-05	4	21	2	HP:0030442
HumanPheno	Anal margin neoplasm	POGLUT1 POFUT1	9.67e-05	4	21	2	HP:0030440
HumanPheno	Digital pitting scar	POGLUT1 POFUT1	9.67e-05	4	21	2	HP:0031293
HumanPheno	Keratoacanthoma	POGLUT1 POFUT1	1.61e-04	5	21	2	HP:0031525
HumanPheno	Penile freckling	POGLUT1 POFUT1	2.40e-04	6	21	2	HP:0031447
HumanPheno	Inguinal freckling	POGLUT1 POFUT1	3.36e-04	7	21	2	HP:0030052
HumanPheno	Hyperpigmented papule	POGLUT1 POFUT1	3.36e-04	7	21	2	HP:0025473
Domain	-	AP2A1 AP2A2	1.63e-05	2	76	2	2.60.40.1030
Domain	AP2_complex_asu	AP2A1 AP2A2	1.63e-05	2	76	2	IPR017104
Domain	Clathrin_a-adaptin_app_sub_C	AP2A1 AP2A2	1.63e-05	2	76	2	IPR003164
Domain	Clathrin_a-adaptin_app_Ig-like	AP2A1 AP2A2	1.63e-05	2	76	2	IPR013038
Domain	Alpha_adaptin_C	AP2A1 AP2A2	1.63e-05	2	76	2	PF02296
Domain	TIMP	TIMP1 TIMP4	9.75e-05	4	76	2	PF00965
Domain	NTR	TIMP1 TIMP4	9.75e-05	4	76	2	SM00206
Domain	TIMP_CS	TIMP1 TIMP4	9.75e-05	4	76	2	IPR030490
Domain	TIMP	TIMP1 TIMP4	9.75e-05	4	76	2	IPR001820
Domain	-	TIMP1 TIMP4	9.75e-05	4	76	2	3.90.370.10
Domain	TIMP_C	TIMP1 TIMP4	9.75e-05	4	76	2	IPR027465
Domain	-	AP2A1 AP2A2	9.75e-05	4	76	2	3.30.310.30
Domain	TIMP	TIMP1 TIMP4	9.75e-05	4	76	2	PS00288
Domain	Clathrin_a/coatomer_app_sub_C	AP2A1 AP2A2	9.75e-05	4	76	2	IPR015873
Domain	Coatomer/calthrin_app_sub_C	AP2A1 AP2A2	4.50e-04	8	76	2	IPR009028
Domain	Cys-rich_flank_reg_C	LRIG1 LRRC26 ADGRA2 AMIGO1	4.96e-04	90	76	4	IPR000483
Domain	LRRCT	LRIG1 LRRC26 ADGRA2 AMIGO1	4.96e-04	90	76	4	SM00082
Domain	Clathrin_a/b/g-adaptin_app_Ig	AP2A1 AP2A2	5.77e-04	9	76	2	IPR008152
Domain	Alpha_adaptinC2	AP2A1 AP2A2	5.77e-04	9	76	2	PF02883
Domain	Alpha_adaptinC2	AP2A1 AP2A2	5.77e-04	9	76	2	SM00809
Domain	Coatomer/clathrin_app_Ig-like	AP2A1 AP2A2	1.05e-03	12	76	2	IPR013041
Domain	Ig_I-set	PRTG LRIG1 MDGA2 MERTK AMIGO1	1.06e-03	190	76	5	IPR013098
Domain	I-set	PRTG LRIG1 MDGA2 MERTK AMIGO1	1.06e-03	190	76	5	PF07679
Domain	Sugar/inositol_transpt	SLC2A1 SLC2A4	1.44e-03	14	76	2	IPR003663
Domain	-	PRTG LRIG1 NECTIN2 MDGA2 MERTK IL2RB ADGRA2 PLXNB3 AMIGO1	1.45e-03	663	76	9	2.60.40.10
Domain	IG	PRTG LRIG1 NECTIN2 MDGA2 MERTK ADGRA2 AMIGO1	1.61e-03	421	76	7	SM00409
Domain	Ig_sub	PRTG LRIG1 NECTIN2 MDGA2 MERTK ADGRA2 AMIGO1	1.61e-03	421	76	7	IPR003599
Domain	Clathrin/coatomer_adapt-like_N	AP2A1 AP2A2	1.66e-03	15	76	2	IPR002553
Domain	Adaptin_N	AP2A1 AP2A2	1.66e-03	15	76	2	PF01602
Domain	SUGAR_TRANSPORT_2	SLC2A1 SLC2A4	2.14e-03	17	76	2	PS00217
Domain	Ig-like_fold	PRTG LRIG1 NECTIN2 MDGA2 MERTK IL2RB ADGRA2 PLXNB3 AMIGO1	2.22e-03	706	76	9	IPR013783
Domain	IG_LIKE	PRTG LRIG1 NECTIN2 MDGA2 MERTK ADGRA2 AMIGO1	3.81e-03	491	76	7	PS50835
Domain	NTR	TIMP1 TIMP4	3.91e-03	23	76	2	PS50189
Domain	Netrin_domain	TIMP1 TIMP4	3.91e-03	23	76	2	IPR001134
Domain	SUGAR_TRANSPORT_1	SLC2A1 SLC2A4	4.26e-03	24	76	2	PS00216
Domain	Ig-like_dom	PRTG LRIG1 NECTIN2 MDGA2 MERTK ADGRA2 AMIGO1	4.34e-03	503	76	7	IPR007110
Domain	Leu-rich_rpt	LRRC75B LRIG1 LRRC26 ADGRA2 AMIGO1	4.95e-03	271	76	5	IPR001611
Domain	TIMP-like_OB-fold	TIMP1 TIMP4	4.99e-03	26	76	2	IPR008993
Domain	LRR_8	LRIG1 LRRC26 ADGRA2 AMIGO1	5.22e-03	171	76	4	PF13855
Domain	Leu-rich_rpt_typical-subtyp	LRIG1 LRRC26 ADGRA2 AMIGO1	5.89e-03	177	76	4	IPR003591
Domain	LRR_TYP	LRIG1 LRRC26 ADGRA2 AMIGO1	5.89e-03	177	76	4	SM00369
Domain	Thioredoxin	QSOX1 PDIA2	7.04e-03	31	76	2	PF00085
Domain	LRRNT	LRIG1 LRRC26 AMIGO1	7.47e-03	98	76	3	IPR000372
Domain	LRRNT	LRIG1 LRRC26 AMIGO1	7.47e-03	98	76	3	SM00013
Domain	Sugar_transporter_CS	SLC2A1 SLC2A4	7.49e-03	32	76	2	IPR005829
Domain	ig	NECTIN2 MDGA2 MERTK AMIGO1	7.53e-03	190	76	4	PF00047
Domain	Immunoglobulin	NECTIN2 MDGA2 MERTK AMIGO1	7.53e-03	190	76	4	IPR013151
Pathway	REACTOME_VLDLR_INTERNALISATION_AND_DEGRADATION	AP2A1 AP2A2 PCSK9	3.95e-05	16	60	3	M27761
Pathway	REACTOME_VLDLR_INTERNALISATION_AND_DEGRADATION	AP2A1 AP2A2 PCSK9	3.95e-05	16	60	3	MM15506
Pathway	REACTOME_LDL_CLEARANCE	AP2A1 AP2A2 PCSK9	5.72e-05	18	60	3	MM15565
Pathway	REACTOME_LDL_CLEARANCE	AP2A1 AP2A2 PCSK9	6.77e-05	19	60	3	M27846
Pathway	WP_SCFA_AND_SKELETAL_MUSCLE_SUBSTRATE_METABOLISM	PYY SLC2A4	2.64e-04	6	60	2	M39453
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM	POGLUT1 POFUT1	2.64e-04	6	60	2	M27068
Pathway	WP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX	CYP4F8 CYP4F12 PTGS1	3.65e-04	33	60	3	MM15918
Pathway	REACTOME_NEF_MEDIATED_CD8_DOWN_REGULATION	AP2A1 AP2A2	3.69e-04	7	60	2	M27044
Pathway	REACTOME_PLASMA_LIPOPROTEIN_CLEARANCE	AP2A1 AP2A2 PCSK9	3.99e-04	34	60	3	MM15566
Pathway	PID_HIF2PATHWAY	EPO EFNA1 SLC2A1	3.99e-04	34	60	3	M44
Pathway	REACTOME_PLASMA_LIPOPROTEIN_CLEARANCE	AP2A1 AP2A2 PCSK9	5.14e-04	37	60	3	M27847
Pathway	BIOCARTA_RECK_PATHWAY	TIMP1 TIMP4	6.29e-04	9	60	2	MM1579
Pathway	BIOCARTA_RECK_PATHWAY	TIMP1 TIMP4	6.29e-04	9	60	2	M22068
Pathway	KEGG_MEDICUS_REFERENCE_HIF_1_SIGNALING_PATHWAY	TGFB1 SLC2A1	6.29e-04	9	60	2	M47421
Pathway	REACTOME_NEF_MEDIATED_CD4_DOWN_REGULATION	AP2A1 AP2A2	6.29e-04	9	60	2	M27011
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_SURFACTANT_METABOLISM	ABCA3 SFTPB	7.84e-04	10	60	2	M27573
Pathway	REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING	AP2A1 AP2A2	9.56e-04	11	60	2	MM14694
Pathway	WP_PLURIPOTENT_STEM_CELL_DIFFERENTIATION_PATHWAY	TGFB1 EPO FLT3LG	1.11e-03	48	60	3	M39427
Pathway	REACTOME_EICOSANOIDS	CYP4F8 CYP4F12	1.14e-03	12	60	2	M27129
Pathway	REACTOME_EICOSANOIDS	CYP4F8 CYP4F12	1.14e-03	12	60	2	MM14845
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2	AP2A1 AP2A2	1.14e-03	12	60	2	MM15163
Pathway	REACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS	EFNA1 AP2A1 AP2A2	1.32e-03	51	60	3	M27311
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2	AP2A1 AP2A2	1.35e-03	13	60	2	M27415
Pathway	KEGG_MEDICUS_VARIANT_LOSS_OF_VHL_TO_HIF_1_SIGNALING_PATHWAY	TGFB1 SLC2A1	1.57e-03	14	60	2	M47422
Pathway	REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING	AP2A1 AP2A2	1.57e-03	14	60	2	M10122
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4	AP2A1 AP2A2	1.57e-03	14	60	2	MM15161
Pathway	WP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES	CYP4F8 CYP4F12	1.57e-03	14	60	2	MM15842
Pathway	REACTOME_FATTY_ACIDS	CYP4F8 CYP4F12	1.81e-03	15	60	2	M27126
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4	AP2A1 AP2A2	1.81e-03	15	60	2	M27413
Pathway	BIOCARTA_ERYTH_PATHWAY	TGFB1 EPO	1.81e-03	15	60	2	M9367
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	GLMP TMUB1 QSOX1 SUMF2 PIANP POGLUT1 PPT2 TEX101 SCPEP1 MDGA2 CDHR5 SERINC2 CYP4F12 C16orf89	3.12e-08	985	77	14	12975309
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	TGFB1 SUMF2 POGLUT1 TM9SF2 TIMP1 XPO6 TMEM165 NECTIN2 GAS1 SCPEP1 TMEM214 POFUT1 DNAJC1 PTGS1 PCSK9	5.15e-08	1201	77	15	35696571
Pubmed	Gene expression changes during the development of acute lung injury: role of transforming growth factor beta.	TGFB1 TIMP1 SFTPB	3.63e-07	7	77	3	16100012
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	TMUB1 CNNM4 SUMF2 TM9SF2 AP2A1 LRIG1 SCARF2 XPO6 TMEM165 NECTIN2 TMEM214 POFUT1	1.06e-06	942	77	12	31073040
Pubmed	Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor.	TGFB1 ADGRA2 SLC2A1	1.24e-06	10	77	3	21282641
Pubmed	The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α.	EPO CYBRD1 SLC2A1	2.94e-06	13	77	3	27325674
Pubmed	Different Regulation of Glut1 Expression and Glucose Uptake during the Induction and Chronic Stages of TGFβ1-Induced EMT in Breast Cancer Cells.	TGFB1 SLC2A1	4.84e-06	2	77	2	33271824
Pubmed	Regulation of GLUT transporters by flavonoids in androgen-sensitive and -insensitive prostate cancer cells.	SLC2A1 SLC2A4	4.84e-06	2	77	2	24932809
Pubmed	Cooperative Effect of Erythropoietin and TGF-β Inhibition on Erythroid Development in Human Pluripotent Stem Cells.	TGFB1 EPO	4.84e-06	2	77	2	26012423
Pubmed	Imbalance of tissue inhibitors of metalloproteinases (TIMP) - 1 and - 4 serum levels, in patients with inflammatory bowel disease.	TIMP1 TIMP4	4.84e-06	2	77	2	19036126
Pubmed	ESRRB Inhibits the TGFβ Signaling Pathway to Drive Cell Proliferation in Cervical Cancer.	TGFB1 ESRRB	4.84e-06	2	77	2	37350664
Pubmed	Indinavir uncovers different contributions of GLUT4 and GLUT1 towards glucose uptake in muscle and fat cells and tissues.	SLC2A1 SLC2A4	4.84e-06	2	77	2	12712244
Pubmed	Diabetes and obesity during pregnancy alter insulin signalling and glucose transporter expression in maternal skeletal muscle and subcutaneous adipose tissue.	SLC2A1 SLC2A4	4.84e-06	2	77	2	19955252
Pubmed	Differential effects of GLUT1 or GLUT4 overexpression on hexosamine biosynthesis by muscles of transgenic mice.	SLC2A1 SLC2A4	4.84e-06	2	77	2	8798515
Pubmed	The TGFβ system and TIMP1 and 3 genotypes in Turner syndrome-Relation with aortic congenital malformations.	TGFB1 TIMP1	4.84e-06	2	77	2	36890688
Pubmed	Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins).	AP2A1 AP2A2	4.84e-06	2	77	2	2564002
Pubmed	ABCA3 is critical for lamellar body biogenesis in vivo.	ABCA3 SFTPB	4.84e-06	2	77	2	17540762
Pubmed	Somatic cell-like features of cloned mouse embryos prepared with cultured myoblast nuclei.	SLC2A1 SLC2A4	4.84e-06	2	77	2	12606377
Pubmed	A potential role for glucose transporters in the evolution of human brain size.	SLC2A1 SLC2A4	4.84e-06	2	77	2	21986508
Pubmed	[The relationship between TGFbeta1 and TIMP-1 and its effects on the diagnosis of hepatic fibrosis].	TGFB1 TIMP1	4.84e-06	2	77	2	17456311
Pubmed	Transforming growth factor beta-1 upregulates glucose transporter 1 and glycolysis through canonical and noncanonical pathways in hepatic stellate cells.	TGFB1 SLC2A1	4.84e-06	2	77	2	34790014
Pubmed	Induction of human T cell leukemia virus type I receptors on quiescent naive T lymphocytes by TGF-beta.	TGFB1 SLC2A1	4.84e-06	2	77	2	15778389
Pubmed	Differential effects of GLUT-1 or GLUT-4 overexpression on insulin responsiveness in transgenic mice.	SLC2A1 SLC2A4	4.84e-06	2	77	2	7977725
Pubmed	Sequence, tissue distribution, and differential expression of mRNA for a putative insulin-responsive glucose transporter in mouse 3T3-L1 adipocytes.	SLC2A1 SLC2A4	4.84e-06	2	77	2	2654938
Pubmed	Insulin-sensitive regulation of glucose transport and GLUT4 translocation in skeletal muscle of GLUT1 transgenic mice.	SLC2A1 SLC2A4	4.84e-06	2	77	2	9854024
Pubmed	TGF-β1 and TIMP-4 regulate atrial fibrosis in atrial fibrillation secondary to rheumatic heart disease.	TGFB1 TIMP4	4.84e-06	2	77	2	25971370
Pubmed	Targeting glucose consumption and autophagy in myeloma with the novel nucleoside analogue 8-aminoadenosine.	SLC2A1 SLC2A4	4.84e-06	2	77	2	19648108
Pubmed	The Glut1 and Glut4 glucose transporters are differentially expressed during perinatal and postnatal erythropoiesis.	SLC2A1 SLC2A4	4.84e-06	2	77	2	18796630
Pubmed	Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.	CYP4F8 CYP4F12	4.84e-06	2	77	2	16112640
Pubmed	The transition of tissue inhibitor of metalloproteinases from -4 to -1 induces aggressive behavior and poor patient survival in dedifferentiated liposarcoma via YAP/TAZ activation.	TIMP1 TIMP4	4.84e-06	2	77	2	31074490
Pubmed	TGFβ1 synergizes with FLT3 ligand to induce chemoresistant quiescence in acute lymphoblastic leukemia with MLL gene rearrangements.	TGFB1 FLT3LG	4.84e-06	2	77	2	28917156
Pubmed	3T3-L1 adipocyte glucose transporter (HepG2 class): sequence and regulation of protein and mRNA expression by insulin, differentiation, and glucose starvation.	SLC2A1 SLC2A4	4.84e-06	2	77	2	2190533
Pubmed	Erythropoietin decreases renal fibrosis in mice with ureteral obstruction: role of inhibiting TGF-beta-induced epithelial-to-mesenchymal transition.	TGFB1 EPO	4.84e-06	2	77	2	17389738
Pubmed	Novel role of TGF-beta in differential astrocyte-TIMP-1 regulation: implications for HIV-1-dementia and neuroinflammation.	TGFB1 TIMP1	4.84e-06	2	77	2	16496359
Pubmed	Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake.	SLC2A1 SLC2A4	4.84e-06	2	77	2	28589878
Pubmed	Profibrotic up-regulation of glucose transporter 1 by TGF-β involves activation of MEK and mammalian target of rapamycin complex 2 pathways.	TGFB1 SLC2A1	4.84e-06	2	77	2	27480571
Pubmed	Cloning, physical mapping and structural characterization of the human alpha(A)-adaptin gene.	AP2A1 AP2A2	4.84e-06	2	77	2	12036598
Pubmed	Biglycan and decorin differentially regulate signaling in the fetal membranes.	TGFB1 TIMP1 TIMP4	5.72e-06	16	77	3	24373743
Pubmed	GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.	TGFB1 TIMP1 ADGRA2 SLC2A1	9.21e-06	59	77	4	21421844
Pubmed	Periodontitis aggravates kidney damage in obese mice by MMP2 regulation.	TGFB1 TIMP1	1.45e-05	3	77	2	29322806
Pubmed	Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses.	AP2A1 AP2A2	1.45e-05	3	77	2	35014951
Pubmed	A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2.	AP2A1 AP2A2	1.45e-05	3	77	2	18032517
Pubmed	Insulin receptor and glucose transporters mRNA expression throughout the menstrual cycle in human endometrium: a physiological and cyclical condition of tissue insulin resistance.	SLC2A1 SLC2A4	1.45e-05	3	77	2	22971162
Pubmed	TIMP1, TIMP2, and TIMP4 are increased in aqueous humor from primary open angle glaucoma patients.	TIMP1 TIMP4	1.45e-05	3	77	2	26539028
Pubmed	GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle.	SLC2A1 SLC2A4	1.45e-05	3	77	2	22681646
Pubmed	Genetic disorders of surfactant dysfunction.	ABCA3 SFTPB	1.45e-05	3	77	2	19220077
Pubmed	Ocular TGF-β, Matrix Metalloproteinases, and TIMP-1 Increase with the Development and Progression of Diabetic Retinopathy in Type 2 Diabetes Mellitus.	TGFB1 TIMP1	1.45e-05	3	77	2	34257518
Pubmed	Population and disease-based prevalence of the common mutations associated with surfactant deficiency.	ABCA3 SFTPB	1.45e-05	3	77	2	18317237
Pubmed	Sustained hypoglycemia affects glucose transporter expression of human blood leukocytes.	SLC2A1 SLC2A4	1.45e-05	3	77	2	12064911
Pubmed	Triiodothyronine acutely stimulates glucose transport into L6 muscle cells without increasing surface GLUT4, GLUT1, or GLUT3.	SLC2A1 SLC2A4	1.45e-05	3	77	2	22663547
Pubmed	Expression of glucose transporters in epithelial ovarian carcinoma: correlation with clinical characteristics and tumor angiogenesis.	SLC2A1 SLC2A4	1.45e-05	3	77	2	17611657
Pubmed	Serum proteins TGFBI, PCSK9, and CCL14 are potential biomarkers for different traditional Chinese medicine syndromes of multidrug-resistant tuberculosis.	TGFB1 PCSK9	1.45e-05	3	77	2	31909895
Pubmed	Surfactant proteins gene variants in premature newborn infants with severe respiratory distress syndrome.	ABCA3 SFTPB	1.45e-05	3	77	2	29255193
Pubmed	Population-based frequency of surfactant dysfunction mutations in a native Chinese cohort.	ABCA3 SFTPB	1.45e-05	3	77	2	26547207
Pubmed	Relations of TGF-beta1 with HIF-1 alpha, GLUT-1 and longer survival of colorectal cancer patients.	TGFB1 SLC2A1	1.45e-05	3	77	2	19142800
Pubmed	AP2 adaptor complex mediates bile salt export pump internalization and modulates its hepatocanalicular expression and transport function.	AP2A1 AP2A2	1.45e-05	3	77	2	22262466
Pubmed	GLUT1 and Bcl-xL in relation to erythropoietin in human colorectal adenocarcinomas.	EPO SLC2A1	1.45e-05	3	77	2	21033220
Pubmed	Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated Cytotoxicity.	AP2A1 AP2A2	1.45e-05	3	77	2	26269175
Pubmed	Impact of pre-gestational and gestational diabetes mellitus on the expression of glucose transporters GLUT-1, GLUT-4 and GLUT-9 in human term placenta.	SLC2A1 SLC2A4	1.45e-05	3	77	2	27981520
Pubmed	Human telomerase is regulated by erythropoietin and transforming growth factor-beta in human erythroid progenitor cells.	TGFB1 EPO	1.45e-05	3	77	2	17713555
Pubmed	A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.	AP2A1 AP2A2	1.45e-05	3	77	2	19129443
Pubmed	Interaction of Shc with adaptor protein adaptins.	AP2A1 AP2A2	1.45e-05	3	77	2	8617812
Pubmed	Transforming growth factor-β1 decreases erythropoietin production through repressing hypoxia-inducible factor 2α in erythropoietin-producing cells.	TGFB1 EPO	1.45e-05	3	77	2	34724959
Pubmed	The role of serum biomarkers in predicting fibrosis progression in pediatric and adult hepatitis C virus chronic infection.	TGFB1 TIMP1	1.45e-05	3	77	2	21858035
Pubmed	[To study of the nasal mucosa remodeling of allergic rhinitis patients].	TGFB1 TIMP1	1.45e-05	3	77	2	22667130
Pubmed	Suppression of PPAR-gamma attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes.	SLC2A1 SLC2A4	1.45e-05	3	77	2	17389706
Pubmed	Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice.	TGFB1 LRIG1	1.45e-05	3	77	2	33759564
Pubmed	Analysis of correlations between the placental expression of glucose transporters GLUT-1, GLUT-4 and GLUT-9 and selected maternal and fetal parameters in pregnancies complicated by diabetes mellitus.	SLC2A1 SLC2A4	1.45e-05	3	77	2	28969476
Pubmed	The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein.	AP2A1 AP2A2	1.45e-05	3	77	2	8662627
Pubmed	Disruption of the tissue inhibitor of metalloproteinase-1 gene results in altered reproductive cyclicity and uterine morphology in reproductive-age female mice.	TIMP1 TIMP4	1.45e-05	3	77	2	10952938
Pubmed	Chromosomal mapping of five mouse G protein gamma subunits.	TGFB1 SFTPB NECTIN2	1.56e-05	22	77	3	10191100
Pubmed	SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation.	TGFB1 EPO TIMP1	1.79e-05	23	77	3	36414671
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	TGFB1 TMUB1 QSOX1 SUMF2 CYP4F8 CYBRD1 TM9SF2 AP2A1 NECTIN2 STEAP3 TMEM214	2.15e-05	1061	77	11	33845483
Pubmed	Generation of Transgenic Mice that Conditionally Overexpress Tenascin-C.	TGFB1 TIMP1 TIMP4	2.32e-05	25	77	3	33763067
Pubmed	Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention.	TIMP1 TIMP4	2.89e-05	4	77	2	10225966
Pubmed	The role of TIMPs in regulation of extracellular matrix proteolysis.	TIMP1 TIMP4	2.89e-05	4	77	2	25805621
Pubmed	Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.	CYP4F8 CYP4F12	2.89e-05	4	77	2	22665481
Pubmed	Structural analysis of the GLUT1 facilitative glucose transporter (review).	SLC2A1 SLC2A4	2.89e-05	4	77	2	11681785
Pubmed	Disruption of the murine Ap2β1 gene causes nonsyndromic cleft palate.	AP2A1 AP2A2	2.89e-05	4	77	2	20500056
Pubmed	Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.	CYP4F8 CYP4F12	2.89e-05	4	77	2	11185557
Pubmed	Matrix metalloproteinases and oral cancer.	TIMP1 TIMP4	2.89e-05	4	77	2	10621841
Pubmed	Placental glucose transfer and fetal growth.	SLC2A1 SLC2A4	2.89e-05	4	77	2	12583599
Pubmed	Genetic variants in TNFα, TGFB1, PTGS1 and PTGS2 genes are associated with diisocyanate-induced asthma.	TGFB1 PTGS1	2.89e-05	4	77	2	25721048
Pubmed	Matrix metalloproteinases 7 and 9 and their types 1 and 4 tissue inhibitors in tumors and plasma of patients with colorectal cancer.	TIMP1 TIMP4	2.89e-05	4	77	2	18214300
Pubmed	The sentrin-conjugating enzyme mUbc9 interacts with GLUT4 and GLUT1 glucose transporters and regulates transporter levels in skeletal muscle cells.	SLC2A1 SLC2A4	2.89e-05	4	77	2	10655495
Pubmed	E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A).	TIMP1 TIMP4	2.89e-05	4	77	2	12475252
Pubmed	Age-associated alterations in cardiac and skeletal muscle glucose transporters, insulin and IGF-1 receptors, and PI3-kinase protein contents in the C57BL/6 mouse.	SLC2A1 SLC2A4	2.89e-05	4	77	2	10100151
Pubmed	α1A-Adrenergic receptor prevents cardiac ischemic damage through PKCδ/GLUT1/4-mediated glucose uptake.	SLC2A1 SLC2A4	2.89e-05	4	77	2	26832303
Pubmed	[Pathologic study of expression and significance of matrix metalloproteinases-9, tissue inhibitor of metalloproteinase-1, vascular endothelial growth factor and transforming growth factor beta-1 in papillary carcinoma and follicular carcinoma of thyroid].	TGFB1 TIMP1	2.89e-05	4	77	2	20193458
Pubmed	Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state.	TIMP1 TIMP4	2.89e-05	4	77	2	25150980
Pubmed	Prenatal Exposure to Sodium Arsenite Alters Placental Glucose 1, 3, and 4 Transporters in Balb/c Mice.	SLC2A1 SLC2A4	2.89e-05	4	77	2	26339590
Pubmed	LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice.	ABCA3 SFTPB	2.89e-05	4	77	2	20407208
Pubmed	Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene.	TIMP1 TIMP4	2.89e-05	4	77	2	11988080
Pubmed	Expression of hyaluronan synthase in intraocular proliferative diseases: regulation of expression in human vascular endothelial cells by transforming growth factor-beta.	TGFB1 HAS1	2.89e-05	4	77	2	14636845
Pubmed	Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking.	SLC2A1 SLC2A4	2.89e-05	4	77	2	14562105
Pubmed	Immunohistochemical localization and quantification of glucose transporters in the mouse brain.	SLC2A1 SLC2A4	2.89e-05	4	77	2	11955709
Pubmed	The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-beta 1.	TGFB1 TIMP1	2.89e-05	4	77	2	12525489
Pubmed	Specific changes in plasma concentrations of matrix metalloproteinase-2 and -9, TIMP-1 and TGF-beta1 in patients with distinct types of primary glomerulonephritis.	TGFB1 TIMP1	2.89e-05	4	77	2	17205957
Pubmed	The insulin-sensitive glucose transporter, GLUT4, interacts physically with Daxx. Two proteins with capacity to bind Ubc9 and conjugated to SUMO1.	SLC2A1 SLC2A4	2.89e-05	4	77	2	11842083
Pubmed	The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction.	AP2A1 AP2A2	2.89e-05	4	77	2	12646615
Interaction	DPP4 interactions	VANGL2 CNNM4 CPAMD8 TMEM165 TEX101 AGPAT1 NECTIN2 STEAP3 POFUT1 SLC2A1	5.92e-06	453	74	10	int:DPP4
Interaction	TMPRSS11B interactions	VANGL2 CNNM4 TM9SF2 LRIG1 TMEM165 NECTIN2 STEAP3 TMEM214 DNAJC1	2.11e-05	416	74	9	int:TMPRSS11B
Interaction	DPEP2 interactions	QSOX1 POGLUT1 AGPAT1 PCSK9	3.13e-05	49	74	4	int:DPEP2
Interaction	C1orf54 interactions	TGFB1 POGLUT1 LRIG1 AGPAT1 CRTAC1 PCSK9	3.44e-05	167	74	6	int:C1orf54
Interaction	B3GAT1 interactions	VANGL2 ABCA3 TMEM165 AGPAT1 NECTIN2 STEAP3 DNAJC1 SLC2A1	7.15e-05	377	74	8	int:B3GAT1
Interaction	LYZL1 interactions	TGFB1 POGLUT1 PPT2 LRIG1 PCSK9	7.38e-05	118	74	5	int:LYZL1
Interaction	LDLRAD1 interactions	SCARF2 MYO19 AGPAT1 TMEM214 DNAJC1 AMIGO1	9.11e-05	199	74	6	int:LDLRAD1
Interaction	FBXO2 interactions	TGFB1 QSOX1 POGLUT1 PPT2 LRIG1 TIMP1 POFUT1 MERTK	1.30e-04	411	74	8	int:FBXO2
Interaction	LY86 interactions	TGFB1 CNNM4 POGLUT1 TIMP1 AGPAT1 PCSK9	1.46e-04	217	74	6	int:LY86
Interaction	SPINT2 interactions	VANGL2 TMUB1 ABCA3 SCARF2 TMEM214	1.54e-04	138	74	5	int:SPINT2
Interaction	ISLR interactions	QSOX1 POGLUT1 MYO19 AGPAT1 PCSK9	1.54e-04	138	74	5	int:ISLR
Interaction	LMBR1L interactions	TMUB1 CNNM4 SUMF2 TM9SF2 AP2A1 LRIG1 SCARF2 XPO6 TMEM165 NECTIN2 TMEM214 POFUT1	1.59e-04	946	74	12	int:LMBR1L
Interaction	SFTPC interactions	CNNM4 QSOX1 TM9SF2 SCARF2 AGPAT1 PTGS1	1.66e-04	222	74	6	int:SFTPC
Cytoband	17p13	USP6 SLC2A4	1.50e-03	34	77	2	17p13
Cytoband	7q22	EPO ACHE	1.88e-03	38	77	2	7q22
Cytoband	19p13.1	CYP4F8 CYP4F12	2.98e-03	48	77	2	19p13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	TGFB1 FLT3LG AP2A1 TEX101 NECTIN2 PTH2 HAS1	3.88e-03	1192	77	7	chr19q13
GeneFamily	Tissue inhibitor of metallopeptidases	TIMP1 TIMP4	5.04e-05	4	53	2	892
GeneFamily	Endogenous ligands	TGFB1 EPO FLT3LG PYY PTH2	6.38e-04	237	53	5	542
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PRTG LRIG1 MDGA2 MERTK	1.26e-03	161	53	4	593
GeneFamily	Immunoglobulin like domain containing	NECTIN2 MDGA2 MERTK ADGRA2	2.45e-03	193	53	4	594
GeneFamily	Cytochrome P450 family 4	CYP4F8 CYP4F12	4.98e-03	36	53	2	1003
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	TGFB1 GLMP QSOX1 CYP4F8 EFNA1 TM9SF2 AP2A2 NECTIN2 STEAP3 DNAJC1 ADGRA2 PTGS1 SLC2A1	8.75e-08	681	77	13	M5314
Coexpression	MILI_PSEUDOPODIA_CHEMOTAXIS_DN	QSOX1 CYP4F8 ABCA3 TM9SF2 AP2A2 STEAP3 SCPEP1 POFUT1 PTGS1 SLC2A1	9.10e-07	457	77	10	M1613
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	TGFB1 GLMP QSOX1 EFNA1 TM9SF2 AP2A2 NECTIN2 STEAP3 DNAJC1 ADGRA2 PTGS1 SLC2A1	9.42e-07	703	77	12	MM1055
Coexpression	TRAVAGLINI_LUNG_SIGNALING_ALVEOLAR_EPITHELIAL_TYPE_2_CELL	QSOX1 ABCA3 SFTPB CRTAC1 C16orf89	2.15e-06	71	77	5	M41661
Coexpression	HALLMARK_APICAL_SURFACE	GAS1 IL2RB SLC2A4 PCSK9	8.55e-06	44	77	4	M5916
Coexpression	MILI_PSEUDOPODIA_CHEMOTAXIS_DN	QSOX1 ABCA3 TM9SF2 AP2A2 STEAP3 SCPEP1 POFUT1 PTGS1 SLC2A1	9.73e-06	470	77	9	MM1053
Coexpression	DESCARTES_ORGANOGENESIS_NEURAL_TUBE	PRTG SCUBE2 SLC2A1	2.68e-05	20	77	3	MM3659
Coexpression	GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_DN	AP2A1 AP2A2 TIMP1 NECTIN2 GAS1 TMEM214	2.77e-05	200	77	6	M9084
Coexpression	NABA_MATRISOME_ASSOCIATED	TGFB1 EPO CPAMD8 FLT3LG SCUBE2 TIMP1 SFTPB TIMP4 ADAMTS8 PLXNB3	6.82e-05	751	77	10	M5885
Coexpression	WINTER_HYPOXIA_METAGENE	TGFB1 EPO QSOX1 EFNA1 PTGS1 SLC2A1	8.17e-05	243	77	6	M14072
Coexpression	VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP	TGFB1 ATG9B EFNA1 TIMP1 PTGS1	1.20e-04	163	77	5	M12112
Coexpression	MIKKELSEN_DEDIFFERENTIATED_STATE_DN	TGFB1 GAS1	1.77e-04	7	77	2	MM1260
Coexpression	MIKKELSEN_DEDIFFERENTIATED_STATE_DN	TGFB1 GAS1	1.77e-04	7	77	2	M1927
Coexpression	NABA_MATRISOME	TGFB1 ZP1 EPO CPAMD8 FLT3LG SCUBE2 TIMP1 SFTPB TIMP4 ADAMTS8 PLXNB3	1.97e-04	1026	77	11	M5889
Coexpression	KONDO_HYPOXIA	FLT3LG TIMP1	2.36e-04	8	77	2	M7407
Coexpression	TRAVAGLINI_LUNG_ADVENTITIAL_FIBROBLAST_CELL	CYBRD1 TIMP1 GAS1 SCPEP1 HAS1 C16orf89	2.39e-04	296	77	6	M41675
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MID_AIRWAY_SMC_2_CELL	LRIG1 TM7SF2 ADAMTS8 SLC2A1 C16orf89	2.40e-04	189	77	5	M45678
Coexpression	CUI_DEVELOPING_HEART_C6_EPICARDIAL_CELL	CYBRD1 TIMP1 PDIA2 HAS1 PTGS1	2.77e-04	195	77	5	M39303
Coexpression	GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_DN	LRRC75B POGLUT1 PPT2 CYP4F12 ADGRA2	2.90e-04	197	77	5	M5780
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	TGFB1 SCUBE2 ESRRB NECTIN2 GAS1 PTH2 CRTAC1 SERINC2 ADAMTS8 SLC2A4 SLC4A11	2.91e-04	1074	77	11	M1941
Coexpression	GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_DN	GLMP TIMP1 NECTIN2 DNAJC1 SLC2A1	2.97e-04	198	77	5	M3792
Coexpression	GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_DN	POGLUT1 CYBRD1 GAS1 PDIA2 SLC2A4	2.97e-04	198	77	5	M5545
Coexpression	GSE17721_CTRL_VS_CPG_0.5H_BMDC_UP	TMUB1 QSOX1 TM9SF2 TMEM165 PTGS1	3.04e-04	199	77	5	M3754
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	LRRC75B SCUBE2 ACHE PYY PTH2 SERINC2 ADGRA2	3.05e-04	438	77	7	M1954
Coexpression	NABA_MATRISOME_ASSOCIATED	TGFB1 EPO FLT3LG SCUBE2 TIMP1 SFTPB TIMP4 ADAMTS8 PLXNB3	3.09e-04	738	77	9	MM17058
Coexpression	GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP	TGFB1 LRIG1 MERTK IL2RB SLC4A11	3.11e-04	200	77	5	M6514
Coexpression	GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_UP	FLT3LG MERTK IL2RB SLC2A4 C16orf89	3.11e-04	200	77	5	M8843
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	LRRC75B SCUBE2 ACHE PYY PTH2 SERINC2 ADGRA2	3.13e-04	440	77	7	MM832
CoexpressionAtlas	lung	ABCA3 ST8SIA6 SFTPB CRTAC1 ADAMTS8 PCSK9 C16orf89	4.02e-06	182	76	7	lung
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 CYBRD1 SFTPB TM7SF2 CRTAC1 PCSK9 C16orf89	1.76e-09	195	77	8	37aa6e4123d37de4de42ca68d3020f2a7686ce02
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 EFNA1 CYBRD1 SFTPB TM7SF2 CRTAC1 C16orf89	1.83e-09	196	77	8	9d267dd293fde05f04febc0a9d15776c5b782a1c
ToppCell	Biopsy_Control_(H.)-Epithelial-AT2\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	PRTG ABCA3 EFNA1 CYBRD1 SFTPB TM7SF2 CRTAC1 C16orf89	2.06e-09	199	77	8	5323d49d3be980605b3e609b7f03bddba6e50e8a
ToppCell	(7)_Epithelial-D_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 PCSK9 C16orf89	4.02e-08	190	77	7	832d6d3ad14665e50623afe1b8586ccae1a97de5
ToppCell	AT2_cells-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	PRTG ABCA3 CYBRD1 SFTPB TM7SF2 CRTAC1 C16orf89	4.02e-08	190	77	7	46dfab02c1b4a403b7efc871707b6a189eefd4c4
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 CYBRD1 SFTPB TM7SF2 CRTAC1 C16orf89	4.32e-08	192	77	7	5795ad6605565ce194341d08c65aae4b526dac84
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 EFNA1 CYBRD1 SFTPB CRTAC1 PCSK9 C16orf89	4.47e-08	193	77	7	043dd0fc2f93e0bd1ca34ac3e196622b3e91df0f
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 CYBRD1 SFTPB CRTAC1 PCSK9 C16orf89	4.47e-08	193	77	7	ba484fa1f290a92ae02475a4c468b4ac840c133e
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 CYBRD1 SFTPB CRTAC1 PCSK9 C16orf89	4.80e-08	195	77	7	6617abca0009ad3d8731f515f91ab275f9ea4c40
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 CYBRD1 SFTPB CRTAC1 PCSK9 C16orf89	4.80e-08	195	77	7	fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 CYBRD1 SFTPB CRTAC1 PCSK9 C16orf89	4.80e-08	195	77	7	d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 CYBRD1 SFTPB CRTAC1 PCSK9 C16orf89	4.80e-08	195	77	7	3e24570def013d5b0b1ef1d7a5ced7dfd922590b
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 CYBRD1 SFTPB CRTAC1 PCSK9 C16orf89	4.97e-08	196	77	7	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 CYBRD1 SFTPB TM7SF2 CRTAC1 C16orf89	4.97e-08	196	77	7	82b117be41f2e7d677a42d2a5198726eeccb16d0
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 SFTPB TM7SF2 CRTAC1 PCSK9 C16orf89	4.97e-08	196	77	7	b1abecc0aafc09ca70a5fde624f2a998c4aa3341
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 CYBRD1 SFTPB CRTAC1 PCSK9 C16orf89	4.97e-08	196	77	7	006d783a530aa6e1e6545dcc2e6b00bb300fe070
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRTG ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	5.71e-08	200	77	7	3c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	PRTG ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	5.71e-08	200	77	7	c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRTG ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	5.71e-08	200	77	7	65c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	PRTG ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	5.71e-08	200	77	7	40e969883bc302e8fbc6b6ab9814529dc1472902
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	PRTG ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	5.71e-08	200	77	7	ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	PRTG ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	5.71e-08	200	77	7	35c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TIMP1 GAS1 TMEM214 HAS1 PTGS1 C16orf89	7.30e-07	181	77	6	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TIMP1 GAS1 TMEM214 HAS1 PTGS1 C16orf89	7.30e-07	181	77	6	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST8SIA6 LRIG1 ACHE PYY MDGA2 KCNK16	7.54e-07	182	77	6	eb4be1c02b8b033d025e57b8b4cdbfaec4698054
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 CYBRD1 SFTPB CRTAC1 PCSK9 C16orf89	8.83e-07	187	77	6	7c44cec1c26ca5907a495f2d7e633410e2e9728f
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	9.39e-07	189	77	6	6f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 SFTPB ACHE CRTAC1 PCSK9 C16orf89	9.39e-07	189	77	6	da014519d6eb21bc2dc2ed65eafe638b42a068ed
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	9.39e-07	189	77	6	926b5fa3064b501a57ba78583e8af33532add455
ToppCell	368C-Epithelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	9.69e-07	190	77	6	459811e88d3001816c2d89034e0921c24918c17f
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 CYBRD1 SFTPB CRTAC1 ADAMTS8 C16orf89	9.99e-07	191	77	6	f00d6824bd138b192a996e9f7de57b235bb24c18
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCUBE2 TIMP1 SCARF2 GAS1 STEAP3 SCPEP1	9.99e-07	191	77	6	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	COPD-Myeloid-DC_Mature\|Myeloid / Disease state, Lineage and Cell class	POGLUT1 LRIG1 ACHE NECTIN2 MERTK SLC2A1	1.03e-06	192	77	6	baebd462f464e7d0e462d07a74bb5d685a9fc3b6
ToppCell	(7)_Epithelial-C_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.06e-06	193	77	6	a3ca6ab20c8de260e410ddc14d3d202f28b9d6c2
ToppCell	AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	PRTG ABCA3 CYBRD1 SFTPB CRTAC1 C16orf89	1.06e-06	193	77	6	8187f976fd2d11fad3286690f1a046e894772220
ToppCell	(7)_Epithelial_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.09e-06	194	77	6	413e8b9f1e15be363a7f4a8f727af3eeb9e9a928
ToppCell	343B-Epithelial_cells-Epithelial-D_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.09e-06	194	77	6	3944b00a64428579874e1ebd94ef35a294017658
ToppCell	343B-Epithelial_cells-Epithelial-D_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.09e-06	194	77	6	5af1f0ca4c46d9368e5defe33b30c7b4382202bb
ToppCell	AT2_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.13e-06	195	77	6	0792c1e959e933b10ae987d821ff43020dfdabad
ToppCell	(7)_Epithelial-A_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ABCA3 SFTPB TM7SF2 CRTAC1 PCSK9 C16orf89	1.13e-06	195	77	6	c9a6c65ee18d83bf34a4713d306a6e30db1325c2
ToppCell	AT2_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	ABCA3 CYBRD1 SFTPB TM7SF2 CRTAC1 C16orf89	1.13e-06	195	77	6	b0cea3f4e59635913d243612f2e8cf4c7b34e726
ToppCell	343B\|World / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 EFNA1 SFTPB CRTAC1 PCSK9 C16orf89	1.13e-06	195	77	6	2290911fde6efacfa38b985a2541322968bee42d
ToppCell	3'-Parenchyma_lung-Epithelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 CYBRD1 SFTPB CRTAC1 C16orf89	1.13e-06	195	77	6	eec187c087e432417bc346c5d3ead72f58bf3215
ToppCell	ASK440-Epithelial-Type_2\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	PRTG ABCA3 CYBRD1 SFTPB CRTAC1 C16orf89	1.16e-06	196	77	6	754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell	(7)_Epithelial-B_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ABCA3 EFNA1 SFTPB CRTAC1 PCSK9 C16orf89	1.16e-06	196	77	6	345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 EFNA1 CYBRD1 SFTPB CRTAC1 C16orf89	1.16e-06	196	77	6	69f27c2668a9f412b2eb6ca83d11b44863209542
ToppCell	LAM-Epithelial-AT2\|LAM / Condition, Lineage and Cell class	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.16e-06	196	77	6	9165041ef3d56b4d069497fee03dd1c6e273211d
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 EFNA1 CYBRD1 SFTPB CRTAC1 C16orf89	1.16e-06	196	77	6	65e161fd672e37a5d10f28011bb422c4d7042d6a
ToppCell	390C-Epithelial_cells\|390C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.20e-06	197	77	6	78554b26b04752e7cd80402c93a3a491560e8f5f
ToppCell	AT2_cells\|World / lung cells shred on cell class, cell subclass, sample id	ABCA3 CYBRD1 SFTPB TM7SF2 CRTAC1 C16orf89	1.23e-06	198	77	6	92c569c3b8a9fca2d4682cbf77ee8149bcc0a80a
ToppCell	Epithelial_cells\|World / lung cells shred on cell class, cell subclass, sample id	ABCA3 EFNA1 CYBRD1 SFTPB CRTAC1 C16orf89	1.27e-06	199	77	6	bbe69e44b7970f57628365ae771790f2b13d0cae
ToppCell	ASK428-Epithelial\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	ABCA3 EFNA1 CYBRD1 SFTPB CRTAC1 C16orf89	1.27e-06	199	77	6	ba2aaaeb4d9b448a6b9660b152fcac1a0e3fcfe7
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT2\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.27e-06	199	77	6	fa5ddba3ac1ebe712cd4cdc3f20339f7c715d039
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG ABCA3 SFTPB CRTAC1 PCSK9 C16orf89	1.27e-06	199	77	6	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.27e-06	199	77	6	e459d5aa63c83f960562be33cea8182b0556eabf
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.27e-06	199	77	6	e28ace2ca680c6154398e17110aa1838dd7a5548
ToppCell	proximal\|World / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABCA3 LRIG1 SFTPB TM7SF2 CRTAC1 C16orf89	1.31e-06	200	77	6	33f05ed458c889bf241580f513ce66797007248c
ToppCell	proximal-Epithelial-Signaling_Alveolar_Epithelial_Type_2-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRTG ABCA3 SFTPB CRTAC1 PCSK9 C16orf89	1.31e-06	200	77	6	7bd76884fcffdbd9b8d24f5b6b5187ad3963da5f
ToppCell	Lung_Parenchyma-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.31e-06	200	77	6	c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCell	proximal-Epithelial\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.31e-06	200	77	6	3790dd13c4ff471e716e5a2950f196e3c386dbb1
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.31e-06	200	77	6	3ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCell	proximal-3-Epithelial\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.31e-06	200	77	6	08858bb20630849ffb2192631e23466c242a1078
ToppCell	Biopsy_Control_(H.)-Epithelial\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.31e-06	200	77	6	0afd93c4fdcc118bcfa77f3b59f6ff7d9293a7a4
ToppCell	proximal-Epithelial-Signaling_Alveolar_Epithelial_Type_2\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRTG ABCA3 SFTPB CRTAC1 PCSK9 C16orf89	1.31e-06	200	77	6	af57f837eb7f988d24fc4612d16d68121498f0b0
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ABCA3 EFNA1 SFTPB TM7SF2 CRTAC1 C16orf89	1.31e-06	200	77	6	9970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCell	proximal-3-Epithelial-Signaling_Alveolar_Epithelial_Type_2\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRTG ABCA3 SFTPB CRTAC1 PCSK9 C16orf89	1.31e-06	200	77	6	9c7859659843b1566bdf623b269b5e166c89d38c
ToppCell	ASK440-Epithelial\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	ABCA3 EFNA1 CYBRD1 SFTPB CRTAC1 C16orf89	1.31e-06	200	77	6	cb617e2a0ca82b470b473b8d5906bc8879c85718
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pvalb_(MGE-derived_cortical_interneurons--basket_cells)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ESRRB ADIG TMC8 ADAMTS8	1.46e-06	48	77	4	551be574263b25ef971ed9ea897f44707f1f2bb7
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pvalb_(MGE-derived_cortical_interneurons--basket_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ESRRB ADIG TMC8 ADAMTS8	1.46e-06	48	77	4	b4338a4f976425ff055a3dea48b6c1e9d6b49bac
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pvalb_(MGE-derived_cortical_interneurons--basket_cells)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ESRRB ADIG TMC8 ADAMTS8	1.46e-06	48	77	4	1bf16774cec498d4b2b99fcdc5a7a1c3bfec24b8
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFNA1 ST8SIA6 ACHE PYY MDGA2	9.12e-06	162	77	5	ca1014e32996f777bff021830ce9a7cf4acf58d5
ToppCell	normal_Lung-Epithelial_cells-Undetermined\|normal_Lung / Location, Cell class and cell subclass	ABCA3 PIANP SFTPB CRTAC1 C16orf89	9.68e-06	164	77	5	fa2dae15b38cb8f9642dbf00549beec8ee19e9bb
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CYBRD1 TIMP1 GAS1 HAS1 C16orf89	1.03e-05	166	77	5	545f6c91102568791443717e522f89cb3bd1a070
ToppCell	10x5'-lymph-node_spleen-Mast-Mast_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	VANGL2 ST8SIA6 TEX101 HAS1 PTGS1	1.09e-05	168	77	5	650ad3ea52577887885d82457dbc04202ce3eb34
ToppCell	10x5'-lymph-node_spleen-Mast\|lymph-node_spleen / Manually curated celltypes from each tissue	VANGL2 ST8SIA6 TEX101 HAS1 PTGS1	1.09e-05	168	77	5	e58ffbb57c81967766755c3f6f347b158a39cb0d
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRTG SFTPB CRTAC1 MDGA2 TMEM214	1.32e-05	175	77	5	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	POGLUT1 CYBRD1 TIMP1 ADGRA2 PTGS1	1.36e-05	176	77	5	fcf324e6402819683f95e0dd94bf1f777c7f4c76
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PYY TM7SF2 CDHR5 KCNK16 CYP4F12	1.40e-05	177	77	5	5bccc7a74019eae8afd977a9c9134d884857ac27
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)\|390C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 EFNA1 SFTPB CRTAC1 C16orf89	1.48e-05	179	77	5	466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 EFNA1 SFTPB CRTAC1 C16orf89	1.48e-05	179	77	5	f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCell	Club-club-8\|World / Class top	QSOX1 ST8SIA6 SFTPB LRRC26 C16orf89	1.60e-05	182	77	5	8111d917e588008d947021460ddf8f1e7ae1337a
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRRB NECTIN2 GAS1 SERINC2 SLC2A4	1.64e-05	183	77	5	f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCell	10x5'v1-week_17-19-Hematopoietic-erythroid-mid_erythroid\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ACHE STEAP3 CYP4F12 SLC2A1 SLC2A4	1.73e-05	185	77	5	e9059cefcdf0972ec90793b1dd34c3292b17a061
ToppCell	Club\|World / Class top	QSOX1 ST8SIA6 SFTPB LRRC26 C16orf89	1.73e-05	185	77	5	c3caf789e622ed515d143dc594158d52fdcffaef
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCUBE2 SCARF2 GAS1 ADAMTS8 HAS1	1.73e-05	185	77	5	355b03c7ea438681e11a2b872c798c9ea26e1486
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBRD1 SCUBE2 SCARF2 GAS1 HAS1	1.82e-05	187	77	5	976b74d081b7fba8620768613cc26f9262cd7b16
ToppCell	facs-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCUBE2 SCARF2 GAS1 STEAP3 ADAMTS8	1.92e-05	189	77	5	bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCUBE2 SCARF2 GAS1 STEAP3 ADAMTS8	1.92e-05	189	77	5	40cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 SFTPB TMEM165 CRTAC1 C16orf89	1.92e-05	189	77	5	e90ba6f6d7ba0698d04d84278aa035c28803733e
ToppCell	Fibroblasts-CD55+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ABCA3 STEAP3 CRTAC1 HAS1 SLC2A1	1.97e-05	190	77	5	b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIMP1 SCARF2 GAS1 ADAMTS8 HAS1	1.97e-05	190	77	5	97772e69e6f51ebffbb5433ca7b40f1048723220
ToppCell	droplet-Lung-nan-18m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIMP1 SCARF2 GAS1 ADAMTS8 HAS1	1.97e-05	190	77	5	72c2b824acdc43139e6635785df3ed3feb58ec46
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 SFTPB CRTAC1 PCSK9 C16orf89	2.02e-05	191	77	5	6cb2c107bc674aa173b4009f320a1687a76f3979
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCUBE2 SCARF2 GAS1 STEAP3 ADAMTS8	2.02e-05	191	77	5	d4f535b06ad483448ab692e9900c872c78cbed60
ToppCell	(7)_Epithelial-E_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ABCA3 EFNA1 SFTPB TM7SF2 C16orf89	2.02e-05	191	77	5	0fc8d109d5c50957ceef5b8b8b818b0c598b1bbe
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCUBE2 SCARF2 GAS1 STEAP3 ADAMTS8	2.02e-05	191	77	5	b5210de890d338602857b5907135705a507bc2b0
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	ABCA3 LRIG1 SFTPB CRTAC1 C16orf89	2.07e-05	192	77	5	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EFNA1 NECTIN2 GAS1 HAS1 PTGS1	2.07e-05	192	77	5	2f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCell	10x3'2.3-week_12-13-Hematopoietic-erythroid\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PPT2 ACHE STEAP3 SLC2A1 SLC2A4	2.07e-05	192	77	5	6ace9a34ed264583042156ed61c2cb3504a331d2
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCUBE2 TIMP1 SCARF2 GAS1 ADAMTS8	2.07e-05	192	77	5	1b228f0929b505de82a39bf64c837887b0e56701
Drug	(Z)-7-[(1S,4R,6R)-5-[(E)-oct-1-enyl]-2,3-diazabicyclo[2.2.1]hept-2-en-6-yl]hept-5-enoic acid	CYP4F8 CYP4F12 PTGS1	4.22e-06	10	76	3	CID009905657
Drug	azo analog I	CYP4F8 CYP4F12 PTGS1	9.98e-06	13	76	3	CID006438575
Drug	9-(5',5'-difluoro-5'-phosphonopentyl)guanine	AP2A1 AP2A2 ST8SIA6 HAS1	1.68e-05	46	76	4	CID000448999
Drug	Hexoses	SLC2A1 SLC2A4	3.29e-05	3	76	2	ctd:D006601
Drug	Dahuang Zhechong pill	TGFB1 TIMP1	3.29e-05	3	76	2	ctd:C521634
Drug	AC1L4O86	TGFB1 TIMP1	3.29e-05	3	76	2	CID000160771
Drug	Empc	SFTPB ACHE	3.29e-05	3	76	2	CID000167753
Drug	hexaglycine	SLC2A1 SLC2A4	3.29e-05	3	76	2	CID000138069
Drug	lisofylline	TGFB1 FLT3LG AGPAT1 PTGS1	3.44e-05	55	76	4	CID000057782
Disease	Dowling-Degos disease (is_implicated_in)	POGLUT1 POFUT1	1.76e-05	3	72	2	DOID:0060256 (is_implicated_in)
Disease	Hyaline Membrane Disease	ABCA3 SFTPB	1.76e-05	3	72	2	C0020192
Disease	Dowling-Degos disease	POGLUT1 POFUT1	1.76e-05	3	72	2	cv:C3714534
Disease	Respiratory Distress Syndrome	ABCA3 SFTPB	1.76e-05	3	72	2	C0852283
Disease	Dowling-Degos disease 1	POGLUT1 POFUT1	3.51e-05	4	72	2	C4552092
Disease	Hereditary pulmonary alveolar proteinosis	ABCA3 SFTPB	3.51e-05	4	72	2	cv:C3711368
Disease	Reticulate acropigmentation of Kitamura	POGLUT1 POFUT1	3.51e-05	4	72	2	C0406811
Disease	dowling-degos disease	POGLUT1 POFUT1	5.84e-05	5	72	2	C3714534
Disease	IGA Glomerulonephritis	TGFB1 TIMP1 MERTK	7.89e-05	34	72	3	C0017661
Disease	endometrial carcinoma (is_marker_for)	TIMP1 TIMP4 PTGS1	7.89e-05	34	72	3	DOID:2871 (is_marker_for)
Disease	Respiratory Distress Syndrome, Newborn	ABCA3 SFTPB	8.75e-05	6	72	2	C0035220
Disease	Hirschsprung's disease (is_marker_for)	ACHE SLC2A1	8.75e-05	6	72	2	DOID:10487 (is_marker_for)
Disease	myelofibrosis (is_marker_for)	TGFB1 FLT3LG	8.75e-05	6	72	2	DOID:4971 (is_marker_for)
Disease	pulmonary alveolar proteinosis (is_implicated_in)	ABCA3 SFTPB	8.75e-05	6	72	2	DOID:12120 (is_implicated_in)
Disease	Acute Confusional Senile Dementia	ACHE NECTIN2 PYY SLC2A4	1.03e-04	99	72	4	C0546126
Disease	Alzheimer's Disease, Focal Onset	ACHE NECTIN2 PYY SLC2A4	1.03e-04	99	72	4	C0750900
Disease	Alzheimer Disease, Early Onset	ACHE NECTIN2 PYY SLC2A4	1.03e-04	99	72	4	C0750901
Disease	Presenile dementia	ACHE NECTIN2 PYY SLC2A4	1.03e-04	99	72	4	C0011265
Disease	Alzheimer Disease, Late Onset	ACHE NECTIN2 PYY SLC2A4	1.03e-04	99	72	4	C0494463
Disease	Familial Alzheimer Disease (FAD)	ACHE NECTIN2 PYY SLC2A4	1.07e-04	100	72	4	C0276496
Disease	Alzheimer's Disease	ACHE NECTIN2 PYY SLC2A4	1.11e-04	101	72	4	C0002395
Disease	diabetes mellitus (is_marker_for)	TGFB1 TIMP1 SLC2A1	1.39e-04	41	72	3	DOID:9351 (is_marker_for)
Disease	Tumoral calcinosis	TGFB1 EPO TIMP1	1.49e-04	42	72	3	C0263628
Disease	Calcinosis	TGFB1 EPO TIMP1	1.49e-04	42	72	3	C0006663
Disease	Microcalcification	TGFB1 EPO TIMP1	1.49e-04	42	72	3	C0521174
Disease	myasthenia gravis (is_implicated_in)	ACHE IL2RB	1.63e-04	8	72	2	DOID:437 (is_implicated_in)
Disease	aplastic anemia (is_marker_for)	TGFB1 FLT3LG	2.09e-04	9	72	2	DOID:12449 (is_marker_for)
Disease	Diabetes Mellitus, Non-Insulin-Dependent	TGFB1 TIMP1 KCNK16 SLC2A1 SLC2A4	2.10e-04	221	72	5	C0011860
Disease	Kidney Failure, Chronic	TGFB1 EPO PTGS1	2.23e-04	48	72	3	C0022661
Disease	hypertension (biomarker_via_orthology)	TGFB1 CYP4F8 TIMP1 CYP4F12 SLC2A1	2.37e-04	227	72	5	DOID:10763 (biomarker_via_orthology)
Disease	Asthma, Occupational	TGFB1 PTGS1	2.61e-04	10	72	2	C0264423
Disease	response to carboplatin, response to antineoplastic agent	PRTG LRIG1	2.61e-04	10	72	2	GO_0097327, GO_0097328
Disease	Aortic Valve Insufficiency	TGFB1 TIMP1	3.18e-04	11	72	2	C0003504
Disease	Pulmonary Thromboembolisms	EPO MERTK	3.81e-04	12	72	2	C0524702
Disease	Pulmonary Embolism	EPO MERTK	3.81e-04	12	72	2	C0034065
Disease	cholangiocarcinoma (biomarker_via_orthology)	TGFB1 EPO	4.50e-04	13	72	2	DOID:4947 (biomarker_via_orthology)
Disease	cystic fibrosis (is_marker_for)	TGFB1 TIMP1 SFTPB	4.75e-04	62	72	3	DOID:1485 (is_marker_for)
Disease	Liver Cirrhosis, Experimental	TGFB1 PRTG TIMP1 ACHE TMEM165 NECTIN2 IL2RB PTGS1	5.89e-04	774	72	8	C0023893
Disease	Abdominal Aortic Aneurysm	ADAMTS8 PTGS1 PCSK9	6.23e-04	68	72	3	EFO_0004214
Disease	pulmonary fibrosis (is_implicated_in)	TGFB1 SFTPB	6.89e-04	16	72	2	DOID:3770 (is_implicated_in)
Disease	type 1 diabetes mellitus (is_marker_for)	TGFB1 TIMP1 ACHE	7.36e-04	72	72	3	DOID:9744 (is_marker_for)
Disease	Uremia	TGFB1 EPO	7.80e-04	17	72	2	C0041948
Disease	Vascular Diseases	EPO TIMP1	7.80e-04	17	72	2	C0042373
Disease	Oral Submucous Fibrosis	TGFB1 TIMP1	8.76e-04	18	72	2	C0029172
Disease	Gastric ulcer	EPO PTGS1	8.76e-04	18	72	2	C0038358
Disease	schizophrenia, inflammatory bowel disease	EPO TIMP1	8.76e-04	18	72	2	EFO_0003767, MONDO_0005090
Disease	glaucoma (is_marker_for)	EPO PTGS1	1.08e-03	20	72	2	DOID:1686 (is_marker_for)
Disease	breast cancer (is_marker_for)	TGFB1 EPO TIMP1 PTGS1	1.10e-03	185	72	4	DOID:1612 (is_marker_for)
Disease	Alveolitis, Fibrosing	TGFB1 ABCA3 TIMP1	1.11e-03	83	72	3	C4721507
Disease	Pulmonary Fibrosis	TGFB1 ABCA3 TIMP1	1.19e-03	85	72	3	C0034069
Disease	serum alanine aminotransferase measurement	TGFB1 EFNA1 SLC13A1 NECTIN2 CRTAC1 SERINC2 MERTK SLC2A4	1.24e-03	869	72	8	EFO_0004735
Disease	interstitial lung disease (is_marker_for)	TGFB1 SFTPB	1.70e-03	25	72	2	DOID:3082 (is_marker_for)
Disease	pulse pressure measurement	TGFB1 EPO QSOX1 CYBRD1 LRIG1 TIMP1 AGPAT1 PYY CRTAC1 ADAMTS8	1.97e-03	1392	72	10	EFO_0005763
Disease	Iniencephaly	VANGL2 PYY	2.13e-03	28	72	2	C0152234
Disease	Acrania	VANGL2 PYY	2.13e-03	28	72	2	C0702169
Disease	Tethered Cord Syndrome	VANGL2 PYY	2.13e-03	28	72	2	C0080218
Disease	Spinal Cord Myelodysplasia	VANGL2 PYY	2.13e-03	28	72	2	C0344479
Disease	Exencephaly	VANGL2 PYY	2.13e-03	28	72	2	C0266453
Disease	Neurenteric Cyst	VANGL2 PYY	2.13e-03	28	72	2	C0027806
Disease	Diastematomyelia	VANGL2 PYY	2.13e-03	28	72	2	C0011999
Disease	Craniorachischisis	VANGL2 PYY	2.28e-03	29	72	2	C0152426
Disease	Streptozotocin Diabetes	TGFB1 TIMP1 SLC2A4	2.37e-03	108	72	3	C0038433
Disease	Diabetes Mellitus, Experimental	TGFB1 TIMP1 SLC2A4	2.37e-03	108	72	3	C0011853
Disease	Alloxan Diabetes	TGFB1 TIMP1 SLC2A4	2.37e-03	108	72	3	C0002152

Protein segments in the cluster

Peptide	Gene	Start	Entry
LTPLAFLLLPPLLWR	VANGL2	121	Q9ULK5
LRAAPLLAPLWLLAP	nan	86	Q9H8V8
PSLASPLLLLLLWLL	ACHE	11	P22303
DPRGLWLLLPSLSLL	AMIGO1	6	Q86WK6
LLLLLLLTALPPLWS	C16orf89	6	Q6UX73
VFLLPWAPLSLRAFL	CYBRD1	141	Q53TN4
APARLLLPLLPWLLL	ADGRA2	11	Q96PE1
FCLPVGLLLLLIIWL	ADIG	21	Q0VDE8
AAPRWPPLLLLLLLL	ADAMTS8	6	Q9UP79
FVPAPWLSVKLLRLL	AP2A1	251	O95782
LPLLFSGILIWLRLK	ABCA3	31	Q99758
LLWPPLLFTGLLVRP	CDHR5	6	Q9HBB8
PPRTPLLWLLLLLLA	DNAJC1	26	Q96KC8
FVPAPWLSVKLLRLL	AP2A2	251	O94973
WQLFRTLELPLIPIL	POLN	421	Q7Z5Q5
RPWPALTTVLLALLV	PYY	6	P10082
PPSLLLLLLWLLAVP	QSOX1	11	O00391
SSPLRLWLLLFLLPS	POGLUT1	6	Q8NBL1
APRRSPCLLLLWLLL	LRIG1	11	Q96JA1
PCLLLLWLLLLRLEP	LRIG1	16	Q96JA1
LPLLLGLFLPALWRR	MERTK	6	Q12866
WPLLLSIIFIPALLQ	SLC2A1	186	P11166
LLEAIIRLWPLGLVL	MYO19	856	Q96H55
LWPLLLGLTVLPALL	SLC2A4	201	P14672
WLALILPLGPLLLHR	KCNK16	246	Q96T55
PAWSPTTYLLLLLLL	FLT3LG	6	P49771
SRRSWWPLPLLLLLL	PCSK9	6	Q8NBP7
RWPPFGLCLLLLLLS	PLXNB3	21	Q9ULL4
LLHLLLPSLWALPRL	LRRC75B	196	Q2VPJ9
LPSLWALPRLTQLLL	LRRC75B	201	Q2VPJ9
TLALTIALLLWTPLP	MT-ND1	76	P03886
PRGAWTPLASILLLL	GAS1	326	P54826
LPVLLLLLLRASCPW	PDIA2	6	Q13087
LLWFLLFLLLLPPLP	PTGS1	6	P23219
WLFPIIVLISILSPR	MDGA2	941	Q7Z553
LLLLLLLSPLPGVWC	PRTG	21	Q2VWP7
LPGLEVLWSPRALLL	TM7SF2	51	O76062
AAWVLLLLPFLPLLL	PPT2	11	Q9UMR5
RLFPLAWTVLLLPLL	EFNA1	186	P20827
LWPLLPLLLLLLSAR	CPAMD8	6	Q8IZJ3
LRPVAASPWLLLLVV	CYP4F8	11	P98187
LRPVATSPWLLLLLV	CYP4F12	11	Q9HCS2
LSWRLPLLILLLPLA	IL2RB	6	P14784
PLLILLLPLATSWAS	IL2RB	11	P14784
WLLLSLLSLPLGLPV	EPO	11	P01588
LLSPLLTPLFLLFWF	ATG9B	631	Q674R7
VPLLPLALWALLLLG	HAS1	501	Q92839
PSPLLLWTLLLFAAP	GLMP	16	Q8WWB7
RMLPFLLLLWFLPIT	CRTAC1	11	Q9NQ79
PWRTGKLLLTLPLLR	ESRRB	386	O95718
KLSPLGSLPAWLIIL	SLC13A1	461	Q9BZW2
AAWAVLLLLLLLPPL	SCUBE2	11	Q9NQ36
WARPLSVSFLLLLLP	POFUT1	6	Q9H488
LSLLLLPVPLQWIPK	SLC4A11	751	Q8NBS3
LPLLPLLSLLVGAWL	SUMF2	6	Q8NBJ7
LLQWLLLLLPTLCGP	SFTPB	6	P07988
PRWLLLLPLLLGLNA	SCPEP1	11	Q9HB40
LSHLLPLWPLLLLPL	PIANP	11	Q8IYJ0
VLPQTWLLLPLTLRA	PRSS47P	356	A8MTI9
LWASLPLPLLLLASL	SPPL2C	316	Q8IUH8
LLLLLRLLWCPADAP	ST8SIA6	16	P61647
PGRFLPLWLHILLIT	CNNM4	176	Q6P4Q7
PLASGILLLLWLIAP	TIMP1	6	P01033
LTASFVLLPLVWLRP	TMC8	126	Q8IU68
NSSLRPLLWAVLLLP	ZP1	596	P60852
LRLLPAWKVPTLLAL	STEAP3	206	Q658P3
LLLLFLLPTLWFCSP	AGPAT1	16	Q99943
PSPLLPSLLLLLLLW	SCARF2	21	Q96GP6
LLLPLLWLLVLTPGR	TGFB1	11	P01137
QGPRLPWTRLLLLLL	TMEM214	476	Q6NUQ4
LLLLLLLVVPWGVRT	PTH2	16	Q96A98
VWGLQLLLPLLLPSF	TEX101	231	Q9BY14
RPAPSWVLLLRLLAL	TIMP4	6	Q99727
WVLLLRLLALLRPPG	TIMP4	11	Q99727
LLLLFLVPLLWAPAA	TMEM165	16	Q9HC07
PRWPRLLLLSLLLLG	TM9SF2	11	Q99805
LVCRALSNILLLPWP	XPO6	721	Q96QU8
WSDRLALFPLLPKVL	ZBED1	591	O96006
PLLLLLLLLLWYCQI	TMUB1	201	Q9BVT8
LLLYLWTLVAPLLLR	SERINC2	436	Q96SA4
KLDLWRLPPFLIIHL	USP6	1066	P35125
WSRPRPLLLLLLLLS	LRRC26	6	Q2I0M4
PLLWPLLLLLLLETG	NECTIN2	16	Q92692