Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoWide anterior fontanel

FLNA PEX10 CREBBP DICER1 PPP2R5D RTL1 DCHS1 DEPDC5

7.62e-0699548HP:0000260
HumanPhenoAbnormality of the outer ear

FLNA DDX59 OFD1 ITGA8 POMGNT1 PEX10 CRPPA HUWE1 WLS TRIP12 CREBBP PREPL DICER1 BRWD3 STT3A JARID2 FREM2 RAB3GAP1 PPP2R5D RTL1 DCHS1 ALOXE3 DEPDC5 BUB3 CDH2 AGRN ALOX12B NOTCH2

4.89e-0513375428HP:0000356
HumanPhenoAbnormal palate morphology

FLNA COL6A3 DDX59 OFD1 HYAL1 ITGA8 POMGNT1 PEX10 LAMB2 CRPPA HUWE1 WLS TRIP12 CREBBP ADAMTS10 JARID2 FREM2 RAB3GAP1 PPP2R5D RTL1 DCHS1 DLG3 BUB3 CDH2 AGRN NOTCH2

6.54e-0512025426HP:0000174
HumanPhenoAbnormal anterior fontanelle morphology

FLNA PEX10 CREBBP DICER1 PPP2R5D RTL1 DCHS1 DEPDC5

7.76e-05136548HP:0000236
HumanPhenoAbnormal pinna morphology

FLNA DDX59 OFD1 ITGA8 POMGNT1 PEX10 CRPPA HUWE1 WLS TRIP12 CREBBP PREPL BRWD3 STT3A JARID2 FREM2 RAB3GAP1 PPP2R5D RTL1 DCHS1 ALOXE3 DEPDC5 BUB3 CDH2 AGRN ALOX12B NOTCH2

8.77e-0512995427HP:0000377
HumanPhenoFrontal bossing

FLNA DDX59 OFD1 PEX10 CRPPA HUWE1 IDUA WLS CREBBP PREPL DICER1 BRWD3 JARID2 PPP2R5D RTL1 DEPDC5 BUB3 CDH2 NOTCH2

1.12e-047385419HP:0002007
HumanPhenoMacrocephaly

OFD1 POMGNT1 PEX10 CRPPA HUWE1 IDUA DICER1 BRWD3 STT3A JARID2 PPP2R5D RTL1 DEPDC5 CDH2 NOTCH2

1.16e-044915415HP:0000256
HumanPhenoAbnormal shape of the frontal region

FLNA DDX59 OFD1 PEX10 CRPPA HUWE1 IDUA WLS CREBBP PREPL DICER1 BRWD3 JARID2 PPP2R5D RTL1 DEPDC5 BUB3 CDH2 NOTCH2

1.19e-047415419HP:0011218
HumanPhenoAbnormal frontal bone morphology

FLNA DDX59 OFD1 PEX10 CRPPA HUWE1 IDUA WLS CREBBP PREPL DICER1 BRWD3 JARID2 PPP2R5D RTL1 DEPDC5 BUB3 CDH2 NOTCH2

1.21e-047425419HP:0430000
HumanPhenoFrontal hirsutism

FLNA CREBBP RTL1

1.28e-0410543HP:0011335
HumanPhenoAbnormality of the jaws

FLNA COL6A3 DDX59 OFD1 PSMC1 ITGA8 POMGNT1 PEX10 LAMB2 CRPPA HUWE1 IDUA WLS CREBBP PREPL DICER1 STT3A ADAMTS10 JARID2 RAB3GAP1 RTL1 DCHS1 BUB3 AGRN NOTCH2

1.35e-0411755425HP:0000209
HumanPhenoAbnormal jaw morphology

FLNA COL6A3 DDX59 OFD1 PSMC1 ITGA8 POMGNT1 PEX10 LAMB2 CRPPA HUWE1 IDUA WLS CREBBP PREPL DICER1 STT3A ADAMTS10 JARID2 RAB3GAP1 RTL1 DCHS1 BUB3 AGRN NOTCH2

1.37e-0411765425HP:0030791
HumanPhenoIncreased head circumference

OFD1 POMGNT1 PEX10 CRPPA HUWE1 IDUA DICER1 BRWD3 STT3A JARID2 PPP2R5D RTL1 DEPDC5 CDH2 NOTCH2

1.42e-045005415HP:0040194
HumanPhenoBroad distal phalanx of finger

FLNA WLS CREBBP RTL1

1.65e-0427544HP:0009836
HumanPhenoAbnormal mandible morphology

FLNA COL6A3 DDX59 OFD1 PSMC1 ITGA8 POMGNT1 PEX10 LAMB2 CRPPA HUWE1 IDUA WLS CREBBP PREPL DICER1 STT3A JARID2 RAB3GAP1 RTL1 DCHS1 BUB3 AGRN NOTCH2

1.77e-0411185424HP:0000277
HumanPhenoAbnormality of the forehead

FLNA DDX59 OFD1 PEX10 CRPPA HUWE1 IDUA WLS TRIP12 CREBBP PREPL DICER1 BRWD3 STT3A JARID2 FREM2 RAB3GAP1 PPP2R5D RTL1 DCHS1 DEPDC5 BUB3 CDH2 AGRN NOTCH2

2.16e-0412085425HP:0000290
HumanPhenoAbnormality of calvarial morphology

FLNA DDX59 OFD1 PSMC1 PEX10 CRPPA HUWE1 IDUA WLS TRIP12 CREBBP PREPL DICER1 BRWD3 ADAMTS10 JARID2 FREM2 RAB3GAP1 PPP2R5D RTL1 DEPDC5 BUB3 CDH2 NOTCH2

2.23e-0411345424HP:0002648
DomainCadherin

PCDHB3 FREM3 FREM2 FAT1 DCHS1 CDH2 PCDH8

2.39e-051181357IPR002126
DomainCA

PCDHB3 FREM2 FAT1 DCHS1 CDH2 PCDH8

1.88e-041151356SM00112
DomainCadherin-like

SGCA PCDHB3 FAT1 DCHS1 CDH2 PCDH8

1.97e-041161356IPR015919
DomainLH2

PNLIP ALOXE3 ALOX12B

2.78e-04181353SM00308
Domain-

PNLIP ALOXE3 ALOX12B

4.47e-042113532.60.60.20
DomainPLAT

PNLIP ALOXE3 ALOX12B

4.47e-04211353PF01477
DomainPLAT/LH2_dom

PNLIP ALOXE3 ALOX12B

4.47e-04211353IPR001024
DomainPLAT

PNLIP ALOXE3 ALOX12B

4.47e-04211353PS50095
DomainNUT

NUTM2G NUTM2F

5.11e-0451352IPR024310
DomainNUT_N

NUTM2G NUTM2F

5.11e-0451352IPR024309
DomainNUT

NUTM2G NUTM2F

5.11e-0451352PF12881
DomainLipOase_mml

ALOXE3 ALOX12B

7.63e-0461352IPR001885
DomainLIPOXYGENASE_1

ALOXE3 ALOX12B

7.63e-0461352PS00711
DomainLipOase_C

ALOXE3 ALOX12B

7.63e-0461352IPR013819
DomainLIPOXYGENASE_2

ALOXE3 ALOX12B

7.63e-0461352PS00081
DomainLipOase_Fe_BS

ALOXE3 ALOX12B

7.63e-0461352IPR020833
DomainLipOase_CS

ALOXE3 ALOX12B

7.63e-0461352IPR020834
DomainLipoxygenase

ALOXE3 ALOX12B

7.63e-0461352PF00305
DomainLIPOXYGENASE_3

ALOXE3 ALOX12B

7.63e-0461352PS51393
DomainLipOase

ALOXE3 ALOX12B

7.63e-0461352IPR000907
Domain-

TXNRD2 AIFM3

1.06e-03713523.30.390.30
DomainPAP_assoc

TUT4 TUT7

1.06e-0371352PF03828
DomainPAP_assoc

TUT4 TUT7

1.06e-0371352IPR002058
DomainCadherin_CS

PCDHB3 FAT1 DCHS1 CDH2 PCDH8

1.17e-031091355IPR020894
DomainCADHERIN_1

PCDHB3 FAT1 DCHS1 CDH2 PCDH8

1.38e-031131355PS00232
DomainCadherin

PCDHB3 FAT1 DCHS1 CDH2 PCDH8

1.38e-031131355PF00028
DomainPyr_nucl-diS_OxRdtase_dimer

TXNRD2 AIFM3

1.41e-0381352IPR004099
DomainFAD/NAD-linked_Rdtase_dimer

TXNRD2 AIFM3

1.41e-0381352IPR016156
DomainCalx_beta

FREM3 FREM2

1.41e-0381352SM00237
DomainCADHERIN_2

PCDHB3 FAT1 DCHS1 CDH2 PCDH8

1.43e-031141355PS50268
Domain-

PCDHB3 FAT1 DCHS1 CDH2 PCDH8

1.43e-0311413552.60.40.60
DomainCalx_beta

FREM3 FREM2

1.81e-0391352IPR003644
DomainCalx-beta

FREM3 FREM2

1.81e-0391352PF03160
DomainZF_CCHC

XRN2 TUT4 TUT7

2.04e-03351353PS50158
DomainEGF-like_dom

ADAM21 HYAL1 LAMB2 LRP1B FAT1 AGRN NOTCH2

2.24e-032491357IPR000742
DomainLipase/vitellogenin

PNLIP LIPH

2.25e-03101352IPR013818
DomainTAG_lipase

PNLIP LIPH

2.25e-03101352IPR000734
DomainLipase

PNLIP LIPH

2.25e-03101352PF00151
DomainLipase_N

PNLIP LIPH

2.25e-03101352IPR033906
DomainLipase_LIPH

PNLIP LIPH

2.25e-03101352IPR016272
DomainEGF_1

ADAM21 HYAL1 LAMB2 LRP1B FAT1 AGRN NOTCH2

2.56e-032551357PS00022
DomainNTP_transf_2

TUT4 TUT7

2.73e-03111352PF01909
DomainPolymerase_NTP_transf_dom

TUT4 TUT7

2.73e-03111352IPR002934
DomainUQ_con

UBE2NL UBE2O UBE2N

2.79e-03391353PF00179
DomainEGF-like_CS

ADAM21 HYAL1 LAMB2 LRP1B FAT1 AGRN NOTCH2

2.92e-032611357IPR013032
DomainUBIQUITIN_CONJUGAT_1

UBE2NL UBE2O UBE2N

3.00e-03401353PS00183
DomainEGF_2

ADAM21 HYAL1 LAMB2 LRP1B FAT1 AGRN NOTCH2

3.17e-032651357PS01186
DomainUBIQUITIN_CONJUGAT_2

UBE2NL UBE2O UBE2N

3.22e-03411353PS50127
DomainUBQ-conjugat_E2

UBE2NL UBE2O UBE2N

3.22e-03411353IPR000608
DomainFerric_reduct

DUOX1 STEAP3

3.26e-03121352PF01794
DomainWWE

HUWE1 TRIP12

3.26e-03121352PF02825
DomainWWE-dom

HUWE1 TRIP12

3.26e-03121352IPR004170
DomainWWE

HUWE1 TRIP12

3.26e-03121352PS50918
DomainFe3_Rdtase_TM_dom

DUOX1 STEAP3

3.26e-03121352IPR013130
DomainAAA

DNAH2 PSMC1 RNF213 DNAH12 SNRNP200

3.95e-031441355SM00382
DomainAAA+_ATPase

DNAH2 PSMC1 RNF213 DNAH12 SNRNP200

3.95e-031441355IPR003593
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH12

4.46e-03141352IPR024317
DomainDynein_heavy_dom-2

DNAH2 DNAH12

4.46e-03141352IPR013602
DomainDHC_N2

DNAH2 DNAH12

4.46e-03141352PF08393
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH12

4.46e-03141352IPR011704
DomainAAA_8

DNAH2 DNAH12

4.46e-03141352PF12780
DomainAAA_5

DNAH2 DNAH12

4.46e-03141352PF07728
DomainDHC_fam

DNAH2 DNAH12

5.12e-03151352IPR026983
DomainDynein_heavy

DNAH2 DNAH12

5.12e-03151352PF03028
DomainDynein_heavy_dom

DNAH2 DNAH12

5.12e-03151352IPR004273
DomainGuanylate_kinase_CS

MAGI3 DLG3

5.82e-03161352IPR020590
Domain-

UBE2NL UBE2O UBE2N

5.97e-035113533.10.110.10
DomainUBQ-conjugating_enzyme/RWD

UBE2NL UBE2O UBE2N

6.65e-03531353IPR016135
DomainGlycoside_hydrolase_SF

AMY2A HYAL1 IDUA

6.65e-03531353IPR017853
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

CREBBP HDAC3 NCOR1 NOTCH2

3.80e-0528974M6177
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

ATXN2L FLNA RELCH TUT4 SORBS2 MAP2 ACAT1 RTN4 PSMC1 HUWE1 NCLN LRP1B RAB3GAP1 UBE2O PPP2R5D UBE2N HNRNPUL2 GUCY1B1 DLG3 CRYBG3 SEPTIN10 PCDH8

9.99e-1011391392236417873
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

FLNA FBL RTN4 PSMC1 RNF213 NCLN TRIP12 HNRNPUL2 SNRNP200

7.21e-09144139935681168
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

FAM234A LAMB2 NCLN IDUA CTSA STT3A CHPF CDH2 AGRN

2.24e-08164139932409323
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

FAM234A RTN4 TUT7 PSMC1 POMGNT1 LAMB2 RNF213 NCLN WLS CTSA LRP1B STT3A CUTA FAT1 MIA2 HNRNPUL2 CHPF CDH2 AGRN NOTCH2

7.15e-0812011392035696571
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNA OFD1 POMGNT1 LAMB2 HUWE1 TXNRD2 NCLN IDUA ACOX3 NCOR1 FAT1 EHBP1L1 STEAP3 ZER1 DEPDC5 LRRC14 CHPF AGRN NOTCH2

9.58e-0811051391935748872
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

FLNA FAM234A RTN4 TUT7 DNAH2 PSMC1 HUWE1 NCLN WLS TRIP12 STT3A RAB3GAP1 UBE2O PPP2R5D PDS5A CHPF MUL1

2.45e-079421391731073040
Pubmed

HUWE1 and TRIP12 collaborate in degradation of ubiquitin-fusion proteins and misframed ubiquitin.

PSMC1 HUWE1 TRIP12

2.49e-074139323209776
Pubmed

Segmental and restricted localization pattern of Fras1 in the developing meningeal basement membrane in mouse.

LAMB2 FREM3 FREM2

2.49e-074139324101214
Pubmed

HDAC3 is a critical negative regulator of long-term memory formation.

CREBBP HDAC3 NCOR1

2.49e-074139321228185
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ATXN2L TUT4 TUT7 EPB41L5 RNF213 HUWE1 WLS MCRIP1 DICER1 STT3A UBE2O PPP2R5D GUCY1B1 STEAP3 RPAP2

2.72e-077331391534672954
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SORBS2 HUWE1 PREPL HDAC3 NCOR1 UBE2O PPP2R5D AKAP9 UBE2N HNRNPUL2 DCHS1 OTUD4 DLG3 BUB3 CDH2 AGRN PCDH8

3.33e-079631391728671696
Pubmed

The mutational landscape of ocular marginal zone lymphoma identifies frequent alterations in TNFAIP3 followed by mutations in TBL1XR1 and CREBBP.

CREBBP HDAC3 NCOR1

6.21e-075139328152507
Pubmed

Multiple cadherins are expressed in human fibroblasts.

FAT1 DCHS1 CDH2

6.21e-07513939199196
Pubmed

The histone-binding code of nuclear receptor co-repressors matches the substrate specificity of histone deacetylase 3.

CREBBP HDAC3 NCOR1

6.21e-075139315832170
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

XRN2 ZBTB38 SORBS2 PSMC1 MAGI3 HUWE1 TRIP12 LRP1B CREBBP PREPL BRWD3 ZNF879 UBE2O MIA2 OTOF GUCY1B1 CHPF WDR13 SNRNP200

9.42e-0712851391935914814
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

KLK6 INPP1 TENT5C SH2D5 ZNF879 RNF157 NUTM2G JARID2 HDAC3 EHBP1L1 AKAP9 DNAH17 DLG3 KDM7A EEF1AKMT1 SEPTIN10 NUTM2F RPAP2

2.47e-0612421391830973865
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ATXN2L FLNA TUT4 SORBS2 POMGNT1 LAMB2 MAGI3 MCRIP1 L3MBTL1 ASB8 AGRN NOTCH2

2.82e-065601391221653829
Pubmed

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

XRN2 TUT4 ITGA8 CREBBP HDAC3 FREM2 MIA2 CDH2 NOTCH2

4.35e-06307139937499664
Pubmed

Defining the membrane proteome of NK cells.

ATXN2L FLNA XRN2 OFD1 PSMC1 RNF213 HUWE1 NCLN CTSA ACOX3 STT3A NCOR1 EHBP1L1 MIA2 HNRNPUL2 MUL1 NOTCH2

4.55e-0611681391719946888
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

ITGA8 LAMB2 FREM2 AGRN

5.37e-0629139422613833
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

FAM234A ACAT1 RTN4 POMGNT1 PEX10 RNF213 HUWE1 DICER1 STT3A FAT1 SLC9A1 STEAP3 PDS5A SEPTIN10 MUL1 NOTCH2

5.70e-0610611391633845483
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

FLNA COL6A3 UBE2NL AMY2A ACAT1 HYAL1 LAMB2 IDUA CTSA B3GNT8 CUTA FREM2 CILP2 UBE2N FAM151A AGRN

6.33e-0610701391623533145
Pubmed

The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.

COL6A3 FREM3 FREM2

7.34e-0610139315345741
Pubmed

A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.

CREBBP HDAC3 NCOR1

7.34e-0610139314980219
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

OFD1 MAP2 RTN4 EPB41L5 NCLN PREPL DICER1 STT3A RAB3GAP1 UBE2O PPP2R5D R3HCC1L AKAP9 UBE2N ZNF644 STEAP3 CRYBG3 SNRNP200 NOTCH2

7.79e-0614871391933957083
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

TUT4 ADAM21 TUT7 DNAH2 LRP1B CREBBP STT3A ADAMTS10 HDAC3 SULT1B1 UBE2N DNAH17 BUB3

7.97e-067301391334857952
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNA XRN2 ACAT1 FBL TUT7 PSMC1 EPB41L5 HUWE1 TRIP12 CREBBP RAB3GAP1 HNRNPUL2 PDS5A BUB3 WDR13 AGRN SNRNP200 ALOX12B

8.02e-0613531391829467282
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CCDC170 DNAH2 PSMC1 RNF213 MAGI3 HUWE1 TRIP12 FREM2 R3HCC1L UBE2N PDS5A EEF1AKMT1 SNRNP200

8.69e-067361391329676528
Pubmed

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.

CREBBP HDAC3 NCOR1

1.01e-0511139315681609
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

FBL EPB41L5 CTSA CREBBP RAB3GAP1 FAT1 UBE2O ZER1 CHPF NOTCH2 RPAP2

1.06e-055331391125544563
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

WSB1 XRN2 FAM234A SLC36A1 DDX59 SORBS2 PARP8 TUT7 NCLN MIA2 STEAP3 CHPF MUL1

1.06e-057501391311230166
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

FLNA FBL PSMC1 RNF213 HUWE1 HDAC3 NCOR1 UBE2O SNRNP200

1.08e-05344139936282215
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

ATXN2L XRN2 DDX59 FBL TUT7 HUWE1 TRIP12 DICER1 HNRNPUL2 RPAP2

1.18e-054401391034244565
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

ATXN2L FLNA PSMC1 MAGI3 HUWE1 TRIP12 PREPL DICER1 UBE2O UBE2N OTUD4 LRRC14 BUB3 SNRNP200 RPAP2

1.28e-0510051391519615732
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ATXN2L FLNA XRN2 ACAT1 FBL TUT7 HUWE1 TRIP12 DICER1 UBE2O PDS5A SNRNP200

1.32e-056531391222586326
Pubmed

Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology.

HDAC3 NCOR1

1.59e-052139219037247
Pubmed

TUT4/7-mediated uridylation of a coronavirus subgenomic RNAs delays viral replication.

TUT4 TUT7

1.59e-052139237085578
Pubmed

TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms.

TUT4 TUT7

1.59e-052139225979828
Pubmed

Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1.

ALOXE3 ALOX12B

1.59e-052139211773004
Pubmed

Gene network and pathway analysis of mice with conditional ablation of Dicer in post-mitotic neurons.

DICER1 CHPF

1.59e-052139222952873
Pubmed

The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor.

HDAC3 NCOR1

1.59e-052139212861000
Pubmed

Biochemical correlation of activity of the α-dystroglycan-modifying glycosyltransferase POMGnT1 with mutations in muscle-eye-brain disease.

SGCA POMGNT1

1.59e-052139221361872
Pubmed

The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.

TUT4 TUT7

1.59e-052139228665939
Pubmed

RNA uridyl transferases TUT4/7 differentially regulate miRNA variants depending on the cancer cell type.

TUT4 TUT7

1.59e-052139234949722
Pubmed

Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3.

ALOXE3 ALOX12B

1.59e-052139215629692
Pubmed

CRISPR screen identifies the NCOR/HDAC3 complex as a major suppressor of differentiation in rhabdomyosarcoma.

HDAC3 NCOR1

1.59e-052139227956629
Pubmed

The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier.

ALOXE3 ALOX12B

1.59e-052139224021977
Pubmed

Epigenetic regulation of soluble guanylate cyclase (sGC) β1 in breast cancer cells.

HDAC3 GUCY1B1

1.59e-052139227279362
Pubmed

Molecular analysis of 250 patients with autosomal recessive congenital ichthyosis: evidence for mutation hotspots in ALOXE3 and allelic heterogeneity in ALOX12B.

ALOXE3 ALOX12B

1.59e-052139219131948
Pubmed

12R-lipoxygenase deficiency disrupts epidermal barrier function.

ALOXE3 ALOX12B

1.59e-052139217403930
Pubmed

Uridylation by TUT4 and TUT7 marks mRNA for degradation.

TUT4 TUT7

1.59e-052139225480299
Pubmed

Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients.

ALOXE3 ALOX12B

1.59e-052139233435499
Pubmed

Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope.

ALOXE3 ALOX12B

1.59e-052139221558561
Pubmed

Terminal Uridylyltransferases TUT4/7 Regulate microRNA and mRNA Homeostasis.

TUT4 TUT7

1.59e-052139236497000
Pubmed

The interaction between nuclear receptor corepressor and histone deacetylase 3 regulates both positive and negative thyroid hormone action in vivo.

HDAC3 NCOR1

1.59e-052139220427468
Pubmed

USP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2B.

PSMC1 HDAC3 NCOR1

2.20e-0514139327880911
Pubmed

E protein silencing by the leukemogenic AML1-ETO fusion protein.

CREBBP HDAC3 NCOR1

2.20e-0514139315333839
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH2 DNAH12 DNAH17

2.20e-051413939373155
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

PSMC1 LAMB2 NCOR1 FAT1 EHBP1L1 UBE2O AKAP9 LRRC14 BUB3 CHPF ALOX12B RPAP2

2.24e-056891391236543142
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ATXN2L FLNA FAM234A FBL RTN4 LAMB2 NCLN STT3A PPP2R5D MIA2 ZNF644 STEAP3 PDS5A CDH2 SNRNP200 NOTCH2

2.67e-0512031391629180619
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

TUT4 ACAT1 FBL RTN4 TUT7 PSMC1 RNF213 HUWE1 NCLN PREPL STT3A HDAC3 RAB3GAP1 MIA2 AKAP9 HNRNPUL2 ZNF644 CRYBG3

3.05e-0514961391832877691
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

ITGA8 FREM3 FREM2

3.37e-0516139315878328
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

FAM234A PSMC1 EPB41L5 MAGI3 STT3A SLC9A1 EHBP1L1 HNRNPUL2 LRRC14 CDH2 AGRN NOTCH2

3.40e-057191391235337019
Pubmed

The LIFEdb database in 2006.

WSB1 FAM234A SLC36A1 DDX59 SORBS2 PARP8 RTN4 TUT7 NCLN MIA2 STEAP3 MUL1

3.44e-057201391216381901
Pubmed

From ORFeome to biology: a functional genomics pipeline.

WSB1 FAM234A SLC36A1 DDX59 SORBS2 PARP8 RTN4 TUT7 NCLN MIA2 STEAP3 MUL1

3.53e-057221391215489336
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

FAM234A ACAT1 PSMC1 LAMB2 HUWE1 NCLN CTSA STT3A CILP2 CHPF SNRNP200

3.81e-056131391122268729
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

FLNA C5orf22 RTN4 PSMC1 EPB41L5 LAMB2 HUWE1 NCLN PREPL DICER1 STT3A UBE2O HNRNPUL2 SNRNP200

3.82e-059741391428675297
Pubmed

Congenital Muscular Dystrophy Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

COL6A3 POMGNT1 CRPPA

4.08e-0517139320301468
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ATXN2L SORBS2 OFD1 MAP2 PARP8 EPB41L5 MAGI3 MCRIP1 TRIP12 AKAP9 FAM83G CRYBG3 NOTCH2

4.44e-058611391336931259
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

ATXN2L FLNA TUT4 TUT7 LAMB2 OTUD4 SNRNP200

4.71e-05235139730258100
Pubmed

A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations.

CREBBP CDH2

4.75e-053139213678586
Pubmed

3' Uridylation Confers miRNAs with Non-canonical Target Repertoires.

TUT4 TUT7

4.75e-053139231178353
Pubmed

mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome.

TUT4 TUT7

4.75e-053139228792939
Pubmed

Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation.

HDAC3 NCOR1

4.75e-053139217079677
Pubmed

The role of lipoxygenases in epidermis.

ALOXE3 ALOX12B

4.75e-053139223954555
Pubmed

Histone deacetylases and the nuclear receptor corepressor regulate lytic-latent switch gene 50 in murine gammaherpesvirus 68-infected macrophages.

HDAC3 NCOR1

4.75e-053139220719946
Pubmed

Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo.

HDAC3 NCOR1

4.75e-053139223292142
Pubmed

TENT2, TUT4, and TUT7 selectively regulate miRNA sequence and abundance.

TUT4 TUT7

4.75e-053139236071058
Pubmed

Novel mutations in ALOX12B in patients with autosomal recessive congenital ichthyosis and evidence for genetic heterogeneity on chromosome 17p13.

ALOXE3 ALOX12B

4.75e-053139217139268
Pubmed

The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG.

HDAC3 NCOR1

4.75e-053139237735473
Pubmed

Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor.

HDAC3 NCOR1

4.75e-053139224268577
Pubmed

A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells.

HDAC3 NCOR1

4.75e-053139222349439
Pubmed

Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs.

TUT4 TUT7

4.75e-053139223063654
Pubmed

Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo.

HDAC3 NCOR1

4.75e-053139216730330
Pubmed

Mitotic Activation of a Novel Histone Deacetylase 3-Linker Histone H1.3 Protein Complex by Protein Kinase CK2.

HDAC3 NCOR1

4.75e-053139226663086
Pubmed

The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists.

TXNRD2 NCOR1

4.75e-053139215598662
Pubmed

cDNA cloning, genomic structure, and chromosomal localization of a novel murine epidermis-type lipoxygenase.

ALOXE3 ALOX12B

4.75e-053139210366447
Pubmed

Enhanced Reactive Oxygen Species Production, Acidic Cytosolic pH and Upregulated Na+/H+ Exchanger (NHE) in Dicer Deficient CD4+ T Cells.

DICER1 SLC9A1

4.75e-053139228704808
Pubmed

Short-chain fatty acids induce gamma-globin gene expression by displacement of a HDAC3-NCoR repressor complex.

HDAC3 NCOR1

4.75e-053139216849648
Pubmed

Aloxe3 knockout mice reveal a function of epidermal lipoxygenase-3 as hepoxilin synthase and its pivotal role in barrier formation.

ALOXE3 ALOX12B

4.75e-053139222832496
Pubmed

The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene.

HDAC3 NCOR1

4.75e-053139215761026
Pubmed

Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s.

TUT4 TUT7

4.75e-053139230122351
Pubmed

UBC13 is an RNF213-associated E2 ubiquitin-conjugating enzyme, and Lysine 63-linked ubiquitination by the RNF213-UBC13 axis is responsible for angiogenic activity.

RNF213 UBE2N

4.75e-053139233842849
Pubmed

Regulated clearance of histone deacetylase 3 protects independent formation of nuclear receptor corepressor complexes.

HDAC3 NCOR1

4.75e-053139222337871
Pubmed

In vivo repression of an erythroid-specific gene by distinct corepressor complexes.

HDAC3 NCOR1

4.75e-053139211889044
Pubmed

Genotypic and clinical spectrum of self-improving collodion ichthyosis: ALOX12B, ALOXE3, and TGM1 mutations in Scandinavian patients.

ALOXE3 ALOX12B

4.75e-053139219890349
Pubmed

Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density.

CCDC170 WLS

4.75e-053139226911590
Pubmed

Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis.

HDAC3 NCOR1

4.75e-053139234857762
Pubmed

Expression of Fraser syndrome genes in normal and polycystic murine kidneys.

FREM3 FREM2

4.75e-053139221993971
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

DNAH2 NCLN MCRIP1 CREBBP PREPL NCOR1 RAB3GAP1 EHBP1L1 DNAH12 UBE2N OTUD4

5.45e-056381391131182584
InteractionSIRT6 interactions

ATXN2L FLNA XRN2 DDX59 FBL TUT7 HUWE1 TRIP12 CREBBP DICER1 HDAC3 FAT1 HNRNPUL2 ZNF644 PDS5A SNRNP200 RPAP2

1.59e-0662813917int:SIRT6
InteractionGGH interactions

ATXN2L ADAM21 HYAL1 LAMB2 IDUA TRIP12 EHBP1L1 MIA2 SCNN1A CHPF

7.38e-0624313910int:GGH
InteractionNR1D1 interactions

INPP1 HUWE1 HDAC3 NCOR1

2.45e-05251394int:NR1D1
InteractionERG interactions

XRN2 FBL HUWE1 TRIP12 CREBBP NCOR1 HNRNPUL2 WDR13 SNRNP200

2.50e-052231399int:ERG
GeneFamilyDyneins, axonemal

DNAH2 DNAH12 DNAH17

6.50e-0517853536
GeneFamilyArachidonate lipoxygenases

ALOXE3 ALOX12B

3.24e-046852407
GeneFamilyNon-canonical poly(A) polymerases

TUT4 TUT7

4.52e-0478521318
GeneFamilyX-linked mental retardation|RNA helicases

DICER1 SNRNP200

1.17e-03118521168
GeneFamilyRing finger proteins

MARCHF10 PEX10 RNF213 TRIM39 RNF157 MUL1

1.88e-0327585658
GeneFamilyCadherin related

FAT1 DCHS1

2.84e-031785224
CoexpressionGSE8835_CD4_VS_CD8_TCELL_UP

DDX59 RTN4 HUWE1 ACOX3 NCOR1 OTUD4 STEAP3 PDS5A SNRNP200

1.20e-062001389M6254
CoexpressionCUI_DEVELOPING_HEART_TRABECULAR_ATRIAL_CARDIOMYOCYTE

WSB1 RTN4 LAMB2 WLS FREM2 FAT1 AKAP9 CDH2

5.04e-061791388M39308
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_200

RELCH TUT4 C5orf22 EPB41L5 HUWE1 AKAP9 AGRN

6.06e-08541397gudmap_developingKidney_e15.5_cortic collect duct_200_k3
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500

RELCH TUT4 C5orf22 ITGA8 EPB41L5 HUWE1 NCOR1 AKAP9 ZNF644 OTUD4 AGRN

9.04e-0820113911gudmap_developingKidney_e15.5_500_k3
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#2_top-relative-expression-ranked_500

TUT4 C5orf22 EPB41L5 HUWE1 AKAP9 AGRN

1.75e-06561396gudmap_developingKidney_e15.5_Proximal Tubules_500_k2
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#3_top-relative-expression-ranked_1000

RELCH TUT4 C5orf22 EPB41L5 HUWE1 AKAP9 OTUD4 AGRN

7.31e-061521398gudmap_developingKidney_e15.5_Proximal Tubules_1000_k3
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_500

RELCH TUT4 C5orf22 AKAP9 OTUD4 AGRN

3.58e-05941396gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k4
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000

RELCH TUT4 C5orf22 ITGA8 EPB41L5 HUWE1 TRIP12 AKAP9 ZNF644 OTUD4 AGRN

3.74e-0537513911gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_500

RELCH TUT4 C5orf22 ITGA8 EPB41L5 HUWE1 NCOR1 AKAP9 ZNF644 OTUD4 AGRN

6.99e-0540213911gudmap_developingKidney_e15.5_anlage of loop of Henle_500
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_200

RELCH TUT4 C5orf22 EPB41L5 HUWE1 AKAP9 AGRN

7.66e-051561397gudmap_developingKidney_e15.5_cortic collect duct_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_500

HUWE1 BRWD3 NCOR1 CDH2 PCDH8

9.62e-05701395gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k5
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_500

RELCH C5orf22 EPB41L5 HUWE1 AKAP9 OTUD4 AGRN

1.01e-041631397gudmap_developingKidney_e15.5_cortic collect duct_500_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#1_top-relative-expression-ranked_1000

PCDHB3 HUWE1 TRIP12 BRWD3 RNF157 NCOR1 UBE2N GUCY1B1 CDH2 PCDH8

1.03e-0434913910DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k1_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_1000

PCDHB3 ITGA8 HUWE1 TRIP12 CREBBP BRWD3 RNF157 NCOR1 EHBP1L1 UBE2N GUCY1B1 LIPH OTUD4 CDH2 AGRN PCDH8

1.03e-0482613916DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_500

ITGA8 HUWE1 PREPL BRWD3 NCOR1 EHBP1L1 LIPH OTUD4 CDH2 AGRN PCDH8

1.05e-0442113911gudmap_developingLowerUrinaryTract_e14.5_ bladder_500
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#3_top-relative-expression-ranked_500

RELCH TUT4 SORBS2 C5orf22 AKAP9 AGRN

1.22e-041171396gudmap_developingKidney_e15.5_Medullary collecting duct_500_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#2_top-relative-expression-ranked_500

HUWE1 BRWD3 RNF157 NCOR1 CDH2 PCDH8

2.35e-041321396DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k2_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

SLC36A1 SORBS2 MAP2 HYAL1 EPB41L5 LAMB2 RNF157 FAT1 RGS8 AKAP9 RTL1 PDS5A ZER1 KDM7A WDR13 CDH2

2.51e-0489313916Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K3
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_500

COL6A3 RELCH TUT4 C5orf22 ITGA8 EHBP1L1 AKAP9 OTUD4 FAM118A AGRN

2.70e-0439313910gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#3_top-relative-expression-ranked_1000

HUWE1 BRWD3 RNF157 NCOR1 CDH2 PCDH8

2.99e-041381396gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k3
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#4

SORBS2 MAP2 HYAL1 FAT1 RTL1

3.15e-04901395Facebase_RNAseq_e8.5_Floor Plate_500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

MOK RELCH ZBTB38 HYAL1 TUT7 EPB41L5 TRIM39 HUWE1 PREPL NCOR1 R3HCC1L AKAP9 ASB8 PDS5A CDH2

3.66e-0483113915Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_100

SORBS2 ITGA8

4.20e-0451392gudmap_kidney_P3_CapMes_Crym_k3_100
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SORBS2 EPB41L5 MAGI3 FREM2 DUOX1 LIPH FMN1 SCNN1A

2.18e-0719913985f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SORBS2 EPB41L5 MAGI3 FREM2 DUOX1 LIPH FMN1 SCNN1A

2.18e-0719913985cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FLNA SORBS2 FAT1 AKAP9 SCNN1A DEPDC5 AGRN

2.18e-071991398174f6013af6eafa577f84205a62927f2b367fda3
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SORBS2 TENT5C MAGI3 LRP1B FAT1 LIPH SCNN1A

1.72e-061821397215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

WSB1 SORBS2 EPB41L5 MAGI3 FREM2 DUOX1 SCNN1A

2.13e-061881397707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

SORBS2 EPB41L5 MAGI3 FREM2 DUOX1 LIPH SCNN1A

2.37e-061911397e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

SORBS2 EPB41L5 MAGI3 FREM2 DUOX1 LIPH SCNN1A

2.45e-061921397499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAP2 EPB41L5 MAGI3 DUOX1 LIPH SCNN1A AGRN

3.00e-06198139754228dd9a50616d2022712d162a419ed0327cabd
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EPB41L5 MAGI3 FREM2 DUOX1 LIPH FMN1 SCNN1A

3.10e-0619913978587bd98de7767a575088afbea07a1feb4516b9b
ToppCellChildren_(3_yrs)-Immune-monocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC36A1 CD300A TUT7 JARID2 EHBP1L1 FMN1 FAM118A

3.21e-062001397881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MAP2 EPB41L5 MAGI3 DUOX1 LIPH SCNN1A AGRN

3.21e-0620013973d51aebf626dd4656ab4aac8a20d761b8062c42d
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2 TENT5C UBE2O FMN1 DCHS1 CDH2

9.69e-0615613965caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2 TENT5C UBE2O FMN1 DCHS1 CDH2

9.69e-061561396758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPB41L5 MAGI3 FREM2 DUOX1 LIPH SCNN1A

1.08e-051591396e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

AMY2A EPB41L5 MAGI3 FAT1 LIPH SCNN1A

1.08e-0515913968680b054622f573a82b1625fb93c2d5db81d1034
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

EPB41L5 MAGI3 DUOX1 FAT1 LIPH SCNN1A

1.24e-051631396e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

MAP2 EPB41L5 MAGI3 DUOX1 LIPH SCNN1A

2.11e-051791396a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

MAP2 EPB41L5 LAMB2 DUOX1 SCNN1A AGRN

2.18e-0518013962d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAP2 EPB41L5 MAGI3 DUOX1 LIPH SCNN1A

2.39e-0518313967b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo|bone_marrow / Manually curated celltypes from each tissue

ZBTB38 OFD1 PARP8 TENT5C FAM118A BUB3

2.39e-0518313962fb78622adc170dd3301e251418337523de50faf
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

MAP2 EPB41L5 MAGI3 DUOX1 LIPH SCNN1A

2.39e-051831396942530449e9c6583705eeb8f6f12621daea57252
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

MAP2 EPB41L5 MAGI3 LIPH PTPRQ SCNN1A

2.47e-051841396561592edc3083fad41b91811151b442207c65dd9
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

MAP2 EPB41L5 MAGI3 LIPH PTPRQ AGRN

2.62e-05186139609d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAP2 EPB41L5 MAGI3 LIPH PTPRQ AGRN

2.78e-051881396eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RELCH MAGI3 CRPPA PREPL KDM7A NOTCH2

2.78e-0518813966468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RELCH MAGI3 CRPPA PREPL KDM7A NOTCH2

2.78e-0518813967a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RELCH MAGI3 CRPPA PREPL KDM7A NOTCH2

2.78e-0518813969cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

SORBS2 EPB41L5 MAGI3 DUOX1 LIPH SCNN1A

2.78e-051881396c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellCOVID-19-Epithelial-Ionocytes|COVID-19 / Condition, Lineage and Cell class

SORBS2 MARCHF10 FREM2 FAT1 SCNN1A CDH2

2.78e-051881396a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FLNA COL6A3 LAMB2 WLS CHPF CDH2

2.78e-0518813961a751452c0f1f34b3c20fad2fb52c378ab2d0207
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CCDC170 FAM234A BRWD3 SLC9A1 HNRNPUL2 FMN1

2.95e-05190139663018acb7ad80415e861643162abdc2e55968ee4
ToppCellMesenchymal_cells-Smooth_muscle|World / Lineage and Cell class

FLNA SORBS2 MAP2 SGCA ITGA8 GUCY1B1

2.95e-0519013965aa62a363a25f4a110136263b21289a11e8c1e6d
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 MAP2 ITGA8 FAT1 GUCY1B1 CHPF

3.04e-051911396b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SORBS2 TENT5C MAGI3 FAT1 LIPH SCNN1A

3.04e-05191139623776c7302cead3881b39127398f3b3e0d27885e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 RTN4 MAGI3 LIPH SCNN1A SEPTIN10

3.13e-051921396f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

SORBS2 EPB41L5 MAGI3 DUOX1 LIPH SCNN1A

3.13e-051921396efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

CCDC170 MOK DNAH2 DUOX1 DNAH12 LIPH

3.13e-0519213969cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 LAMB2 CILP2 STEAP3 LOXL3 CHPF

3.22e-051931396428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

WSB1 EPB41L5 MAGI3 FREM2 DUOX1 SCNN1A

3.32e-05194139653f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellnormal_Lung-Epithelial_cells-AT1|normal_Lung / Location, Cell class and cell subclass

MAP2 EPB41L5 MAGI3 LIPH SCNN1A AGRN

3.42e-051951396569d1ebc5a5aa110a2430b096755ae35354040c4
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPB41L5 TENT5C MAGI3 FAT1 LIPH SCNN1A

3.42e-051951396dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SORBS2 EPB41L5 MAGI3 DUOX1 LIPH SCNN1A

3.42e-0519513969406866f99555198a9be311fbd65751b70f35446
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WSB1 FLNA LAMB2 FREM2 CHPF CDH2

3.52e-051961396b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP2 EPB41L5 LAMB2 DUOX1 SCNN1A AGRN

3.62e-051971396734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCellMild|World / Condition, Lineage, Cell class and cell subclass

TUT4 PARP8 ZNF880 NCOR1 AKAP9 BUB3

3.62e-051971396476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA SORBS2 MAP2 SGCA ITGA8 GUCY1B1

3.62e-051971396d16bb765afdc02406ffd7ce6a75bae72b66db66c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA SORBS2 MAP2 SGCA ITGA8 GUCY1B1

3.62e-05197139668c23c23b6924892f4c238cf2f5abc7927e04fbc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

WSB1 TUT4 SORBS2 MAP2 RTN4 AKAP9

3.72e-051981396de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EPB41L5 MAGI3 FREM2 DUOX1 LIPH SCNN1A

3.83e-051991396725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RELCH PARP8 RNF213 AKAP9 ZNF644 SNRNP200

3.83e-051991396f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAP2 EPB41L5 MAGI3 DUOX1 LIPH SCNN1A

3.83e-051991396aca81a879ef9c196bd1885eff4c63ffe6c9682b7
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAP2 EPB41L5 MAGI3 DUOX1 SCNN1A AGRN

3.83e-051991396f8846446ebbc4948cdc69640782db1358bbdc486
ToppCellParenchyma_COVID-19-Epithelial-TX-AT1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

MAP2 EPB41L5 MAGI3 DUOX1 SCNN1A AGRN

3.83e-051991396fe9f5bc317be0c35bd96311bf0b3c7b91d98acc5
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAP2 EPB41L5 MAGI3 DUOX1 SCNN1A AGRN

3.83e-0519913963e35ee426ef06f9af568c37349b62dd1ee9b97ea
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAP2 EPB41L5 MAGI3 LIPH SCNN1A AGRN

3.93e-052001396c6f211bbadd0c9be776c58807249e06764df47dc
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAP2 EPB41L5 MAGI3 LIPH SCNN1A AGRN

3.93e-0520013965f7e8d8b05c90a10313775f9f126eb4ab0fe4f67
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

MAP2 EPB41L5 MAGI3 LIPH SCNN1A AGRN

3.93e-052001396e3a80626941363bfc9d97ef906d38c97080aecb1
ToppCellControl-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZBTB38 TUT7 TENT5C SEPTIN10 CHPF

9.22e-051451395fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

IGFN1 RNF157 ASB8 PTPRQ STEAP3

1.26e-041551395d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

MAGI3 DUOX1 FAT1 LIPH SCNN1A

1.34e-04157139531d1bd9138c60e8485664ec4144f987226e3eef9
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OFD1 SESN1 B3GNT8 RAB3GAP1 R3HCC1L

1.42e-04159139574655c22e9fdd88e3052b9dfb954c8fb678bd2d8
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOK CRPPA GUCY1B1 FAM118A TMEM86A

1.46e-041601395a494001b1f6dec33624f98fa3c24bad6988d0425
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP2 PCDHB3 GUCY1B1 LOXL3 CDH2

1.51e-04161139582ed45f144a07856fe92d37426c5f92e259a03a9
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SORBS2 SGCA LAMB2 IDUA LOXL3

1.51e-0416113959703b7e67d9fadb6129cad166bd01be915042e44
ToppCelldroplet-Thymus-nan-21m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300A ITGA8 OTOF ALOXE3 TMEM86A

1.51e-041611395441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCelldroplet-Marrow-BM-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNLIP HYAL1 UBE2O FMN1 SEPTIN10

1.55e-04162139575df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCellfacs-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATXN2L DDX59 PARP8 ACOX3 KDM7A

1.74e-0416613955c132f505dc5f699c87913f140344fc9f8e7e0f5
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2 EPB41L5 MAGI3 LIPH SCNN1A

1.74e-04166139511b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2 EPB41L5 MAGI3 LIPH SCNN1A

1.74e-041661395fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAP2 EPB41L5 MAGI3 LIPH SCNN1A

1.79e-041671395bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAP2 EPB41L5 MAGI3 LIPH SCNN1A

1.79e-0416713959f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCelldroplet-Fat-Bat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARP8 TXNRD2 IDUA B3GNT8 OTOF

1.84e-0416813956fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCelldroplet-Fat-Bat-18m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARP8 TXNRD2 IDUA B3GNT8 OTOF

1.84e-041681395794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF879 FREM2 STEAP3 PDS5A CRYBG3

1.84e-041681395d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCelldroplet-Fat-Bat-18m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARP8 TXNRD2 IDUA B3GNT8 OTOF

1.84e-0416813951e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PARP8 ZNF880 PPP2R5D FMN1 SCNN1A

2.05e-041721395a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Deuterosomal|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CCDC170 MARCHF10 DUOX1 DNAH12 DNAH17

2.05e-04172139508ad76412c9cc3504141797b44b88478ced87476
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAGI3 FREM2 SCNN1A FAM83G AGRN

2.10e-04173139545808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAGI3 FREM2 SCNN1A FAM83G AGRN

2.10e-0417313957fa9dbcb258c3ab974490063951620e2def03db1
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPB41L5 MAGI3 FREM3 FREM2 LIPH

2.10e-041731395b799c06a6a5754668e789f70c0c8bc1508568575
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)-|367C / Donor, Lineage, Cell class and subclass (all cells)

EPB41L5 MAGI3 DUOX1 SCNN1A AGRN

2.16e-041741395edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)|367C / Donor, Lineage, Cell class and subclass (all cells)

EPB41L5 MAGI3 DUOX1 SCNN1A AGRN

2.16e-04174139565539f69100db0b7d90b1b39ee15ab8281f86461
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZNF880 RAB3GAP1 PPP2R5D FMN1 SCNN1A

2.22e-041751395f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDX59 HYAL1 LAMB2 DUOX1 SCNN1A

2.22e-041751395dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 MOK DNAH12 ALOXE3 CKMT1A

2.28e-04176139587de432c680b80555342afac864599bbc002c040
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

EPB41L5 MAGI3 DUOX1 FAT1 LIPH

2.28e-0417613953fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

CRPPA LRP1B SCNN1A CDH2 PCDH8

2.28e-04176139536f77d878a53b30465b0dea8333a3865dba75613
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC170 SORBS2 MAP2 ITGA8 GUCY1B1

2.34e-041771395dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCell15-Trachea-Epithelial-Goblet-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

TENT5C LIPH SCNN1A CHPF CDH2

2.40e-041781395f0557920b9b3e7c4f39938d1b524aa58711af4d2
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 IGFN1 SGCA ITGA8 C22orf31

2.40e-04178139509475e522dc1b8cf9ff1c25de5d1e3082b162948
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 IGFN1 SGCA ITGA8 C22orf31

2.40e-04178139535de8f791b0e78a6caf52ff095f05e204a59e828
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PREPL RTL1 FAM151A FAM83G CDH2

2.40e-041781395fcbbcc44271515de1969b4732b6441c012693d5f
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC170 SORBS2 MAP2 ITGA8 GUCY1B1

2.40e-041781395416f85e51f45ec7949451fd47611a84e33e87245
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 IGFN1 SGCA ITGA8 C22orf31

2.40e-041781395000d25f3f13cc76cf39c46c312c6fafc2ea4f368
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA SORBS2 MAP2 SGCA GUCY1B1

2.46e-0417913958da6863edc756540bb097cc7221c1408640d9bb4
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPB41L5 MAGI3 MIA2 LIPH SCNN1A

2.46e-04179139588dbec952507d84b85b08165eec80df99ed1e736
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPB41L5 MAGI3 MIA2 LIPH SCNN1A

2.46e-041791395daf8189a22786171e2b629261cf720736aa4ebdb
ToppCellCiliated_cells-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CCDC170 MOK MARCHF10 DNAH2 DNAH12

2.46e-0417913950e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPB41L5 MAGI3 FREM2 LIPH SCNN1A

2.46e-041791395cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA SORBS2 MAP2 SGCA GUCY1B1

2.46e-041791395f39c13c99a07d009cc677e363ffe089089c64916
DiseaseOto-Palato-digital syndrome type 1

FLNA OFD1

2.05e-0521342C0265251
DiseaseICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 2

ALOXE3 ALOX12B

2.05e-0521342242100
DiseaseAutosomal recessive congenital ichthyosis 2

ALOXE3 ALOX12B

2.05e-0521342cv:C3888093
DiseaseICHTHYOSIFORM ERYTHRODERMA, CONGENITAL, NONBULLOUS, 1

ALOXE3 ALOX12B

2.05e-0521342C1855792
Diseasecarpal tunnel syndrome

ZBTB38 CRPPA ACOX3 ADAMTS10 R3HCC1L

5.48e-05891345EFO_0004143
Diseasemuscular dystrophy (is_implicated_in)

COL6A3 SGCA POMGNT1

5.94e-05171343DOID:9884 (is_implicated_in)
DiseaseSelf-Healing Collodion Baby

ALOXE3 ALOX12B

6.12e-0531342C1855789
DiseaseIchthyosis Congenita I

ALOXE3 ALOX12B

1.22e-0441342C4551630
DiseaseHarlequin Fetus

ALOXE3 ALOX12B

1.22e-0441342C0239849
DiseaseIchthyosis Congenita II

ALOXE3 ALOX12B

1.22e-0441342C3536797
DiseaseCollodion Fetus

ALOXE3 ALOX12B

1.22e-0441342C3543867
DiseaseMyasthenic Syndromes, Congenital

LAMB2 PREPL AGRN

1.73e-04241343C0751882
DiseaseCongenital ichthyosis

ALOXE3 ALOX12B

2.03e-0451342C0020758
DiseaseOrofaciodigital Syndromes

DDX59 OFD1

3.03e-0461342C0029294
Diseaseproteinuria (implicated_via_orthology)

EPB41L5 LAMB2 SLC9A1

3.40e-04301343DOID:576 (implicated_via_orthology)
DiseaseMuscular Dystrophies, Limb-Girdle

SGCA POMGNT1 CRPPA

4.12e-04321343C0686353
DiseaseWalker-Warburg syndrome (implicated_via_orthology)

POMGNT1 CRPPA

4.24e-0471342DOID:0050560 (implicated_via_orthology)
Diseasesyndromic X-linked intellectual disability (implicated_via_orthology)

HUWE1 KDM7A

5.63e-0481342DOID:0060309 (implicated_via_orthology)
Diseasemitral valve prolapse (is_implicated_in)

FLNA DCHS1

7.22e-0491342DOID:988 (is_implicated_in)
Diseaseretinitis pigmentosa (is_implicated_in)

OFD1 POMGNT1 SNRNP200

8.60e-04411343DOID:10584 (is_implicated_in)
DiseaseCongenital Nonbullous Ichthyosiform Erythroderma

ALOXE3 ALOX12B

1.10e-03111342C0079154
DiseaseCongenital ichthyosis of skin

ALOXE3 ALOX12B

1.10e-03111342cv:C0020758
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

TMEM132E PTPRQ

1.55e-03131342C1846647
DiseaseMental Retardation, X-Linked Nonsyndromic

HUWE1 DLG3

1.55e-03131342C3501611
DiseaseMUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K

POMGNT1 CRPPA

1.80e-03141342C1836373
Diseasealpha-Dystroglycanopathies

POMGNT1 CRPPA

1.80e-03141342C2936406
DiseaseFukuyama Type Congenital Muscular Dystrophy

POMGNT1 CRPPA

1.80e-03141342C0410174
DiseaseMuscle eye brain disease

POMGNT1 CRPPA

1.80e-03141342C0457133
DiseaseAutosomal recessive limb-girdle muscular dystrophy

SGCA POMGNT1

1.80e-03141342cv:C2931907
DiseaseMuscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1

POMGNT1 CRPPA

1.80e-03141342C4284790
DiseaseHuntington's disease (is_marker_for)

MAP2 CREBBP NCOR1

1.82e-03531343DOID:12858 (is_marker_for)
DiseaseProstatic Neoplasms

LAMB2 TXNRD2 LRP1B CREBBP NCOR1 PDS5A ALOXE3 PCDH8 ALOX12B

2.06e-036161349C0033578
DiseaseMalignant neoplasm of prostate

LAMB2 TXNRD2 LRP1B CREBBP NCOR1 PDS5A ALOXE3 PCDH8 ALOX12B

2.06e-036161349C0376358
DiseaseWalker-Warburg congenital muscular dystrophy

POMGNT1 CRPPA

2.07e-03151342C0265221
DiseaseMyasthenic Syndromes, Congenital, Slow Channel

PREPL AGRN

2.36e-03161342C0751885
Diseasemyopia (is_implicated_in)

ZNF644 LOXL3

2.36e-03161342DOID:11830 (is_implicated_in)
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

PREPL AGRN

2.66e-03171342C0751883
Diseaseresponse to radiation, Urinary retention

COL6A3 LRP1B

2.66e-03171342GO_0009314, HP_0000016
DiseaseCongenital Myasthenic Syndromes, Presynaptic

PREPL AGRN

3.33e-03191342C0751884
Diseasenucleus accumbens volume change measurement, age at assessment

CRPPA PNMA8B

4.46e-03221342EFO_0008007, EFO_0021493

Protein segments in the cluster

PeptideGeneStartEntry
EPDESNARYFHVVIA

UBE2N

26

P61088
EPDESNARYFHVVIA

UBE2NL

26

Q5JXB2
THIVAFDAVLFEPSR

FAM234A

476

Q9H0X4
IPELAHSDAYQTREI

AKAP9

2886

Q99996
SDSVKPHDVVREFLV

CRYBG3

1346

Q68DQ2
RTTAHYDPATEEFII

ACOX3

171

O15254
HSVSVVELEETPFRR

AIFM3

356

Q96NN9
LTYEIEPIRHSATFE

ADAM21

141

Q9UKJ8
FVRSVHPYEVAEVIA

CUTA

136

O60888
RAIVDVHFDPTTAFR

AGRN

1201

O00468
HPEAGEVFVRVVASS

CREBBP

1351

Q92793
ITHSRDVVTEAIYPE

PPP2R5D

156

Q14738
DEVFVLEAHPFDQRI

BRWD3

466

Q6RI45
HPEDGIFIRQVTDAE

BUB3

306

O43684
EDRYAEHVAATQALP

C22orf31

161

O95567
VSPELFHVIDDFVQF

DICER1

1761

Q9UPY3
LESYEIAFPTRVDHN

ADAMTS10

36

Q9H324
FELAVDAVHRKASEP

ATXN2L

156

Q8WWM7
SDHVTVDSPYVVAVR

R3HCC1L

386

Q7Z5L2
EFVVIAPAAHSDAVL

RAB3GAP1

126

Q15042
VSTVDEFPEARGEHV

OTUD4

906

Q01804
ERIAPVHIDSEAISA

PDS5A

616

Q29RF7
KETIAIRPAAHAEFV

FMN1

351

Q68DA7
SPERHIFGEDRVVSE

OFD1

686

O75665
VVIIHDAVRPFVEEG

CRPPA

151

A4D126
LETVAAHQFPEVRFS

NCLN

341

Q969V3
EEYVSIIQVDPSRIH

PEX10

71

O60683
IAAIRSFPHDNVEDL

ASB8

26

Q9H765
FVPSDRALVFVDNHD

AMY2A

301

P04746
VPFDAAVDFHRLIAS

DUOX1

1121

Q9NRD9
VAFARHVGPTRVEAE

RELCH

586

Q9P260
VAFVAEELVHSEIPA

DEPDC5

1296

O75140
SKPRSYAHIEESVDV

FAT1

3991

Q14517
HDIVRLLDEYNVTPS

NOTCH2

2056

Q04721
PELGSAFVTVHVRDA

DCHS1

341

Q96JQ0
PLRAEAAFVLHVTDV

DCHS1

451

Q96JQ0
ELRARVPFDYEHTES

DCHS1

2766

Q96JQ0
LARVVHQDVAFTDPT

INPP1

121

P49441
HPQLEADLSAVREIY

PARP8

151

Q8N3A8
ELVSEHAFEIPDNVR

KDM7A

446

Q6ZMT4
ALVQETAYIEDRPLH

LOXL3

536

P58215
DPFEAFIIFSIRHEI

LRP1B

1256

Q9NZR2
FASIFEESHVPVIEE

MAGI3

1136

Q5TCQ9
VRLDPSDAKFVDVIH

PNLIP

206

P16233
EHFTEEAPRRSIAAF

ALOXE3

661

Q9BYJ1
SVHKGVEPVEDRFVF

FREM2

1151

Q5SZK8
PVDAVATEAATIDRH

DDX59

41

Q5T1V6
PALIRVASVEDVEDH

L3MBTL1

531

Q9Y468
VEVEVRDVNDHAPRF

PCDH8

121

O95206
QLTLEPYERDHAVVV

FBL

296

P22087
EEFVFIHAVPVEERV

HNRNPUL2

426

Q1KMD3
HDVIAAARLAYPESA

DNAH12

1081

Q6ZR08
LPERIAAHSFDIVIA

EEF1AKMT1

126

Q8WVE0
ENVDISVTLYRDPHV

EHBP1L1

76

Q8N3D4
FDLVPHEDGVDVAVR

MUL1

126

Q969V5
PAVTIQLDLEAEFHF

LAMB2

131

P55268
AFPFHIIFDRDLVVT

GUCY1B1

216

Q02153
DRLDPSDAQFVDVIH

LIPH

191

Q8WWY8
VAYDPDERIAAHQAL

MOK

266

Q9UQ07
PAVEAFFLVHATERE

HUWE1

3881

Q7Z6Z7
QIHDVPADLLTYDRT

HDAC3

376

O15379
VDFHIPDARTASVLV

ITGA8

61

P53708
ALVYREDDPTAVQIH

PTPRQ

1721

Q9UMZ3
PSHFRYEKDTVVVQD

CTSA

286

P10619
EVFDDLEQHIRSPVV

FAM118A

116

Q9NWS6
LAEHSPELVSEFRFV

EPB41L5

176

Q9HCM4
STLRHEIPEAVVTYE

DNAH17

1666

Q9UFH2
RELLTAVAEVFPHVT

FAM151A

461

Q8WW52
HTFEPAEFIIDTRDA

FLNA

2061

P21333
VVEDHQEVLPFIYRA

C5orf22

21

Q49AR2
HIATDDNLVFTVPEF

COL6A3

391

P12111
DAILSYEPVTRQEIH

DLG3

611

Q92796
AAVLIYASDDTRAHP

IDUA

436

P35475
IHFVEEAPRRSIEAF

ALOX12B

651

O75342
SEIFTPAHEENVRFI

MCRIP1

26

C9JLW8
FPVNSAHEFAVREAE

MARCHF10

531

Q8NA82
RHGVDVDVSVFDVVA

HYAL1

46

Q12794
DEAQDVPLHYAVFTR

IGFN1

1066

Q86VF2
TYDHLSEVPVTREQL

CCDC170

21

Q8IYT3
FVLRAQDDAFVHTPA

B3GNT8

241

Q7Z7M8
LFETPHYVVNVAERA

DNAH2

651

Q9P225
PTAEEEALIEFHRSY

SCNN1A

41

P37088
AEVEEIVFPRQFSKH

CDH2

136

P19022
EVFADLFDPVIQERH

CKMT1A

116

P12532
VYVVRATDLHPADIN

OTOF

1496

Q9HC10
LRIIDVNDHSPVFFE

PCDHB3

121

Q9Y5E6
EFHDPLIYIESVRAQ

JARID2

566

Q92833
SNIELPTRIHEEVYF

MIA2

526

Q96PC5
SEHPALERTLFVVVF

OR2H1

16

Q9GZK4
SEEYFEVREHSVPLR

FAM83G

616

A6ND36
EDFVTKVEAVIHPRF

NUTM2F

451

A1L443
EDFVTKVEAVIHPRF

NUTM2G

436

Q5VZR2
VTILADRYDEPVLHF

FREM3

2001

P0C091
HFVERFSIIAEPLVR

RTL1

821

A6NKG5
HPFRAYLESEVAISE

RTN4

1071

Q9NQC3
HRIFEEFVDVQAPRE

RGS8

106

P57771
RAHTVVPLDDATQEY

TRIM39

136

Q9HCM9
DEEVTPARAVSRHFE

SESN1

316

Q9Y6P5
DLDREVYPLVVHAVV

RNF157

191

Q96PX1
LDEHVATVTQDRAFP

TMEM132E

756

Q6IEE7
EHTAEDPALLYRVET

POMGNT1

431

Q8WZA1
LVEFVEDVNHAAIPR

PNMA8B

66

Q9ULN7
QEFAVPDYRSSHLEV

NCOR1

36

O75376
EFPSLEALVENHAVT

SH2D5

361

Q6ZV89
FAVLRFESVIHEFDP

STT3A

36

P46977
RIVAFADAAVEPIDF

ACAT1

311

P24752
VFDQHVDEAVPRVRF

WDR13

166

Q9H1Z4
FRVAEEHAPSIVFID

PSMC1

271

P62191
AEFLVRSHDAEEVLP

SGCA

136

Q16586
IEQFHSRPDDIVIAT

SULT1B1

31

O43704
IEVTSDEQPRAHVEF

SORBS2

581

O94875
HVALPTEAEFQLVRD

TENT5C

96

Q5VWP2
RDFHDPVVEVEVSVF

CD300A

111

Q9UGN4
PREELHYASVVFDSN

CD300A

261

Q9UGN4
PVTASHFRFARVEAD

CILP2

891

Q8IUL8
DVFAPVKAHVAELER

CHPF

561

Q8IZ52
AATTCDPVVEEHFRR

VGLL4

201

Q14135
DEFSPAVSQAHREAI

RNF213

4041

Q63HN8
ALSAVESREPVEHYR

TMEM86A

221

Q8N2M4
HLAFRDVAIEFPQEE

ZNF880

6

Q6PDB4
VLNAIEAYTEHRPEI

ZER1

356

Q7Z7L7
FFVSRAPEHCELVVD

SLC36A1

361

Q7Z2H8
VSSPEVIFVAVFREH

STEAP3

81

Q658P3
FITPAHYSDVVDERS

RPAP2

81

Q8IXW5
LATHEPNFTIIREEF

XRN2

241

Q9H0D6
ADHPDFRFRTTDIVI

UBE2O

646

Q9C0C9
AVDPVAVLAVFEEIH

SLC9A1

236

P19634
SIHITAYENDERVPL

PREPL

636

Q4J6C6
PVSVQETYEAKRHEF

SEPTIN10

341

Q9P0V9
SHSVRFAALEQPEVE

MAP2

1306

P11137
LSYEARHVVSPEQIA

ZNF644

991

Q9H582
AQDEHLITFFVPVFE

SNRNP200

1246

O75643
ILVDSREATSVPHIY

TXNRD2

341

Q9NNW7
LPAHVQESVTFRDVA

ZNF879

6

B4DU55
EAEPVRTLAEHSYAV

ZBTB38

211

Q8NAP3
LVDHTEVVRDLTFAP

WSB1

166

Q9Y6I7
IPREIEANDIVFSVH

WLS

81

Q5T9L3
SFIDVDADFHARVPV

TUT7

381

Q5VYS8
DADFHARVPVVVCRE

TUT7

386

Q5VYS8
HDLFDIDPVVARSVY

TRIP12

1736

Q14669
IDPVVARSVYHLEDI

TRIP12

1741

Q14669
ESDFHAKVPVVVCRD

TUT4

446

Q5TAX3
QSSVVRAVIHPDYDA

KLK6

86

Q92876
DSVAQAELRTVVHPF

LRRC14

416

Q15048