Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	ZnF_C2HC	FAM90A14 FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	4.92e-09	55	84	7	SM00343
Domain	Znf_CCHC	FAM90A14 FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10	4.92e-09	55	84	7	IPR001878
Domain	EGF_Ca-bd_CS	SLIT2 NELL1 GAS6 LRP2 NOTCH4	7.60e-05	97	84	5	IPR018097
Domain	EGF_CA	SLIT2 NELL1 GAS6 LRP2 NOTCH4	8.38e-05	99	84	5	PS01187
Domain	ASX_HYDROXYL	SLIT2 NELL1 GAS6 LRP2 NOTCH4	8.79e-05	100	84	5	PS00010
Domain	EGF_3	SELP SLIT2 NELL1 RELN GAS6 LRP2 NOTCH4	9.08e-05	235	84	7	PS50026
Domain	EGF	SELP SLIT2 NELL1 RELN GAS6 LRP2 NOTCH4	9.08e-05	235	84	7	SM00181
Domain	EGF-type_Asp/Asn_hydroxyl_site	SLIT2 NELL1 GAS6 LRP2 NOTCH4	1.16e-04	106	84	5	IPR000152
Domain	EGF-like_dom	SELP SLIT2 NELL1 RELN GAS6 LRP2 NOTCH4	1.30e-04	249	84	7	IPR000742
Domain	EGF_1	SELP SLIT2 NELL1 RELN GAS6 LRP2 NOTCH4	1.51e-04	255	84	7	PS00022
Domain	EGF-like_CS	SELP SLIT2 NELL1 RELN GAS6 LRP2 NOTCH4	1.74e-04	261	84	7	IPR013032
Domain	EGF_2	SELP SLIT2 NELL1 RELN GAS6 LRP2 NOTCH4	1.91e-04	265	84	7	PS01186
Domain	EGF_CA	SLIT2 NELL1 GAS6 LRP2 NOTCH4	2.24e-04	122	84	5	SM00179
Domain	EGF-like_Ca-bd_dom	SLIT2 NELL1 GAS6 LRP2 NOTCH4	2.42e-04	124	84	5	IPR001881
Domain	EGF	SELP SLIT2 GAS6 LRP2 NOTCH4	2.60e-04	126	84	5	PF00008
Domain	hEGF	SLIT2 GAS6 NOTCH4	2.65e-04	28	84	3	PF12661
Domain	EGF_CA	NELL1 GAS6 LRP2 NOTCH4	6.11e-04	86	84	4	PF07645
Domain	Growth_fac_rcpt_	NELL1 ERBB3 GAS6 LRP2 NOTCH4	6.92e-04	156	84	5	IPR009030
Domain	Laminin_G_2	SLIT2 NELL1 GAS6	7.69e-04	40	84	3	PF02210
Domain	LamG	SLIT2 NELL1 GAS6	1.02e-03	44	84	3	SM00282
Domain	Laminin_G_1	SLIT2 GAS6	1.07e-03	11	84	2	PF00054
Domain	TIL_dom	VWF LRP2	1.76e-03	14	84	2	IPR002919
Domain	Laminin_G	SLIT2 NELL1 GAS6	2.27e-03	58	84	3	IPR001791
Domain	EGF_extracell	NELL1 RELN LRP2	2.50e-03	60	84	3	IPR013111
Domain	EGF_2	NELL1 RELN LRP2	2.50e-03	60	84	3	PF07974
Domain	CTCK_1	SLIT2 VWF	2.92e-03	18	84	2	PS01185
Domain	VWC_out	NELL1 VWF	3.25e-03	19	84	2	SM00215
Domain	CH	CFAP47 GAS2L2 UTRN	3.87e-03	70	84	3	PF00307
Domain	-	CFAP47 GAS2L2 UTRN	4.02e-03	71	84	3	1.10.418.10
Domain	-	RNF144B RNF2 MEX3D RNF213 PRPF19 USP3 RNF11	4.09e-03	449	84	7	3.30.40.10
Domain	CH	CFAP47 GAS2L2 UTRN	4.35e-03	73	84	3	PS50021
Domain	CT	SLIT2 VWF	4.36e-03	22	84	2	SM00041
Domain	Znf_RING/FYVE/PHD	RNF144B RNF2 MEX3D RNF213 PRPF19 USP3 RNF11	4.61e-03	459	84	7	IPR013083
Domain	CH-domain	CFAP47 GAS2L2 UTRN	4.69e-03	75	84	3	IPR001715
Domain	Cys_knot_C	SLIT2 VWF	5.61e-03	25	84	2	IPR006207
Domain	CTCK_2	SLIT2 VWF	5.61e-03	25	84	2	PS01225
Domain	cEGF	GAS6 LRP2	6.06e-03	26	84	2	IPR026823
Domain	cEGF	GAS6 LRP2	6.06e-03	26	84	2	PF12662
Domain	WD40	FBXW8 PRPF19 ELP2 SPAG16 CFAP44	6.26e-03	259	84	5	PF00400
Domain	WD40_repeat_CS	FBXW8 PRPF19 SPAG16 CFAP44	6.41e-03	164	84	4	IPR019775
Domain	VWC	NELL1 VWF	7.00e-03	28	84	2	PF00093
Domain	WD40	FBXW8 PRPF19 ELP2 SPAG16 CFAP44	7.20e-03	268	84	5	SM00320
Domain	WD40_repeat	FBXW8 PRPF19 ELP2 SPAG16 CFAP44	7.66e-03	272	84	5	IPR001680
Domain	AMP-binding	DIP2B ACSM6	8.01e-03	30	84	2	PF00501
Domain	AMP-dep_Synth/Lig	DIP2B ACSM6	8.01e-03	30	84	2	IPR000873
Domain	WD_REPEATS_1	FBXW8 PRPF19 ELP2 SPAG16 CFAP44	8.37e-03	278	84	5	PS00678
Domain	WD_REPEATS_2	FBXW8 PRPF19 ELP2 SPAG16 CFAP44	8.49e-03	279	84	5	PS50082
Domain	WD_REPEATS_REGION	FBXW8 PRPF19 ELP2 SPAG16 CFAP44	8.49e-03	279	84	5	PS50294
Pubmed	Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	2.45e-25	25	91	12	17684299
Pubmed	Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.00e-20	23	91	10	18602769
Pubmed	Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.	RNF144B FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A26 FAM90A23 FAM90A1 FAM90A7 FAM90A9 FAM90A8 FAM90A10	1.84e-14	164	91	12	22967998
Pubmed	Differential role of von Willebrand factor and P-selectin on microvascular thrombosis in endotoxemia.	SELP VWF	6.77e-06	2	91	2	18802014
Pubmed	von Willebrand factor promotes leukocyte extravasation.	SELP VWF	6.77e-06	2	91	2	20716766
Pubmed	Increased von Willebrand factor, P-selectin and fibrin content in occlusive thrombus resistant to lytic therapy.	SELP VWF	6.77e-06	2	91	2	26962963
Pubmed	Microvesicles from stored red blood cells induce P-selectin and von Willebrand factor release from endothelial cells via a protein kinase C-dependent mechanism.	SELP VWF	6.77e-06	2	91	2	38355315
Pubmed	P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface.	SELP VWF	6.77e-06	2	91	2	14630802
Pubmed	Effects of toll-like receptor-4 gene polymorphisms on soluble P-selectin and von Willebrand factor levels in hypercholesterolemic patients.	SELP VWF	2.03e-05	3	91	2	17849054
Pubmed	Expression and significance of vWF, GMP-140 and ADAMTS13 in patients with aneurysmal subarachnoid hemorrhage.	SELP VWF	2.03e-05	3	91	2	29077161
Pubmed	Platelet adhesion receptors do not modulate infarct volume after a photochemically induced stroke in mice.	SELP VWF	2.03e-05	3	91	2	17996853
Pubmed	Effects of radiofrequency catheter ablation of atrial fibrillation on soluble P-selectin, von Willebrand factor and IL-6 in the peripheral and cardiac circulation.	SELP VWF	2.03e-05	3	91	2	25390649
Pubmed	The expression of von Willebrand factor, soluble thrombomodulin, and soluble p-selectin during orthotopic liver transplantation.	SELP VWF	2.03e-05	3	91	2	17275499
Pubmed	Soluble CD40 ligand, soluble P-selectin and von Willebrand factor levels in subjects with prediabetes: the impact of metabolic syndrome.	SELP VWF	2.03e-05	3	91	2	22100896
Pubmed	Endothelial cell markers in patients with pseudoexfoliation syndrome.	SELP VWF	2.03e-05	3	91	2	22593709
Pubmed	Slit2N Inhibits Transmission of HIV-1 from Dendritic Cells to T-cells by Modulating Novel Cytoskeletal Elements.	SLIT2 SRC	2.03e-05	3	91	2	26582347
Pubmed	Expression of P-selectin, von Willebrand and endothelin-1 after carotid artery stenting.	SELP VWF	2.03e-05	3	91	2	21638248
Pubmed	P-selectin can promote thrombus propagation independently of both von Willebrand factor and thrombospondin-1 in mice.	SELP VWF	2.03e-05	3	91	2	27943541
Pubmed	Endothelial von Willebrand factor recruits platelets to atherosclerosis-prone sites in response to hypercholesterolemia.	SELP VWF	2.03e-05	3	91	2	12036879
Pubmed	Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity.	RNF2 PHC2	4.05e-05	4	91	2	28900001
Pubmed	P-selectin cross-links PSGL-1 and enhances neutrophil adhesion to fibrinogen and ICAM-1 in a Src kinase-dependent, but GPCR-independent mechanism.	SELP SRC	4.05e-05	4	91	2	19262138
Pubmed	The Bmi-1 oncoprotein interacts with dinG and MPh2: the role of RING finger domains.	RNF2 PHC2	4.05e-05	4	91	2	9627119
Pubmed	Lipid raft-associated β-adducin is required for PSGL-1-mediated neutrophil rolling on P-selectin.	SELP SRC	4.05e-05	4	91	2	25425738
Pubmed	Characterisation of alpha-dystrobrevin in muscle.	SRC UTRN	4.05e-05	4	91	2	9701558
Pubmed	Role of Bmi1 in H2A ubiquitylation and Hox gene silencing.	RNF2 PHC2	4.05e-05	4	91	2	16751658
Pubmed	Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins.	SELP VWF	4.05e-05	4	91	2	11071623
Pubmed	Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectin.	SELP VWF	4.05e-05	4	91	2	15956287
Pubmed	Evidence for a cell-specific action of Reelin in the spinal cord.	RELN CHAT	4.05e-05	4	91	2	11900467
Pubmed	AKT-independent Reelin signaling requires interactions of heterotrimeric Go and Src.	RELN SRC	4.05e-05	4	91	2	26441085
Pubmed	The afatinib resistance of in vivo generated H1975 lung cancer cell clones is mediated by SRC/ERBB3/c-KIT/c-MET compensatory survival signaling.	ERBB3 SRC	4.05e-05	4	91	2	26934000
Pubmed	Factors associated with early platelet activation in obese children.	SELP VWF	4.05e-05	4	91	2	24415745
Pubmed	Migration of sympathetic preganglionic neurons in the spinal cord is regulated by Reelin-dependent Dab1 tyrosine phosphorylation and CrkL.	RELN SRC	6.74e-05	5	91	2	17394141
Pubmed	Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase.	VWF SRC	6.74e-05	5	91	2	12393736
Pubmed	Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination.	RNF2 PHC2	6.74e-05	5	91	2	20471950
Pubmed	Inflammation induces hemorrhage in thrombocytopenia.	SELP VWF	6.74e-05	5	91	2	18256319
Pubmed	Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus.	RNF2 PHC2	1.01e-04	6	91	2	17332741
Pubmed	Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression.	SELP VWF	1.01e-04	6	91	2	19332769
Pubmed	NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma.	ERBB3 SRC	1.01e-04	6	91	2	22439932
Pubmed	Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.	SRC GAS6	1.01e-04	6	91	2	25187556
Pubmed	SAM domain polymerization links subnuclear clustering of PRC1 to gene silencing.	RNF2 PHC2	1.01e-04	6	91	2	24091011
Pubmed	Slit2/Robo4 signaling modulates HIV-1 gp120-induced lymphatic hyperpermeability.	SLIT2 SRC	1.01e-04	6	91	2	22241990
Pubmed	Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4.	SLIT2 RELN GUCY1A1	1.37e-04	38	91	3	31624071
Pubmed	Topology and enzymatic properties of a canonical Polycomb repressive complex 1 isoform.	RNF2 PHC2	1.41e-04	7	91	2	31093962
Pubmed	Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling.	VWF SRC	1.41e-04	7	91	2	11389024
Pubmed	Pallial origin of basal forebrain cholinergic neurons in the nucleus basalis of Meynert and horizontal limb of the diagonal band nucleus.	RELN CHAT	1.41e-04	7	91	2	21865321
Pubmed	Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation.	ERBB3 SRC	1.41e-04	7	91	2	21075308
Pubmed	MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1.	RNF2 PHC2	1.41e-04	7	91	2	15563468
Pubmed	Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development.	RELN SRC	1.41e-04	7	91	2	12526739
Pubmed	Stretch-induced fetal type II cell differentiation is mediated via ErbB1-ErbB4 interactions.	ERBB3 SFTPB	1.41e-04	7	91	2	22493501
Pubmed	NMDA-receptor proteins are upregulated in the hippocampus of postnatal heterozygous reeler mice.	RELN SRC	1.41e-04	7	91	2	16438943
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	SELP ERBB3 SLITRK5 LRP2	1.47e-04	101	91	4	23382219
Pubmed	MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells.	RNF2 PHC2	1.88e-04	8	91	2	19369945
Pubmed	Heat stable antigen (mouse CD24) supports myeloid cell binding to endothelial and platelet P-selectin.	SELP VWF	1.88e-04	8	91	2	8562500
Pubmed	Molecular characterization of a novel human gene, SEC13R, related to the yeast secretory pathway gene SEC13, and mapping to a conserved linkage group on human chromosome 3p24-p25 and mouse chromosome 6.	VWF SFTPB	1.88e-04	8	91	2	7987303
Pubmed	Reelin activates SRC family tyrosine kinases in neurons.	RELN SRC	1.88e-04	8	91	2	12526740
Pubmed	Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation.	SLIT2 RELN	1.88e-04	8	91	2	16774856
Pubmed	ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration.	ERBB3 LRP2	1.88e-04	8	91	2	18426980
Pubmed	Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.	SELP VWF	1.88e-04	8	91	2	30936549
Pubmed	HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+ concentration via activation of Src kinase and nitric oxide signaling pathways.	GUCY1A1 SRC	2.41e-04	9	91	2	24666322
Pubmed	RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3.	RNF2 PHC2	2.41e-04	9	91	2	22325148
Pubmed	TIPT2 and geminin interact with basal transcription factors to synergize in transcriptional regulation.	RNF2 PHC2	2.41e-04	9	91	2	19515240
Pubmed	Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3.	RELN SRC	2.41e-04	9	91	2	19129405
Pubmed	Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.	RELN HTR1A CHAT NOTCH4	2.68e-04	118	91	4	19156168
Pubmed	Directional guidance of interneuron migration to the cerebral cortex relies on subcortical Slit1/2-independent repulsion and cortical attraction.	SLIT2 CHAT	3.01e-04	10	91	2	12642493
Pubmed	Slit2N/Robo1 inhibit HIV-gp120-induced migration and podosome formation in immature dendritic cells by sequestering LSP1 and WASp.	SLIT2 SRC	3.01e-04	10	91	2	23119100
Pubmed	The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.	SELP VWF	3.01e-04	10	91	2	12082590
Pubmed	Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons.	RELN SRC	3.01e-04	10	91	2	15062102
Pubmed	Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.	SLIT2 NOTCH4	3.01e-04	10	91	2	17496152
Pubmed	A forward genetic screen in mice identifies mutants with abnormal cortical patterning.	RELN LRP2	3.67e-04	11	91	2	23968836
Pubmed	Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice.	RNF2 PHC2	3.67e-04	11	91	2	12183370
Pubmed	Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes.	RNF2 PHC2	3.67e-04	11	91	2	16024804
Pubmed	AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.	GUCY1A1 SRC	3.67e-04	11	91	2	15381706
Pubmed	Src, Fyn, and Yes are not required for neuromuscular synapse formation but are necessary for stabilization of agrin-induced clusters of acetylcholine receptors.	SRC UTRN	3.67e-04	11	91	2	11312300
Pubmed	Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons.	RELN CHAT	3.67e-04	11	91	2	27170656
Pubmed	Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously.	SLIT2 RELN	4.39e-04	12	91	2	16540508
Pubmed	Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus.	RNF2 PHC2	4.39e-04	12	91	2	19636380
Pubmed	Prothrombotic genetic variants and atherosclerosis in patients with cerebral ischemia of arterial origin.	VWF F13B	5.18e-04	13	91	2	18848323
Pubmed	Cyclin-dependent kinase 5/p35 contributes synergistically with Reelin/Dab1 to the positioning of facial branchiomotor and inferior olive neurons in the developing mouse hindbrain.	RELN CHAT	5.18e-04	13	91	2	12019323
Pubmed	Absence of Fyn and Src causes a reeler-like phenotype.	RELN SRC	5.18e-04	13	91	2	16162939
Pubmed	Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.	VWF NOTCH4	5.18e-04	13	91	2	20558824
Pubmed	p130Cas: a versatile scaffold in signaling networks.	VWF SRC	6.04e-04	14	91	2	16581250
Pubmed	Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.	CNKSR3 ZNF646	6.04e-04	14	91	2	22451204
Pubmed	Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis.	FBXW8 GAS6	6.04e-04	14	91	2	30735494
Pubmed	Integrins and Src: dynamic duo of adhesion signaling.	VWF SRC	6.04e-04	14	91	2	16005629
Pubmed	Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia.	SIRPB2 NOTCH4	6.04e-04	14	91	2	23620142
Pubmed	A simple method for 3D analysis of immunolabeled axonal tracts in a transparent nervous system.	SLIT2 CHAT	6.95e-04	15	91	2	25456121
Pubmed	The characterization of mice with a targeted combined deficiency of protein c and factor XI.	SELP VWF	6.95e-04	15	91	2	11159184
Pubmed	Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor.	RNF2 PHC2	6.95e-04	15	91	2	20601937
Pubmed	Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch.	SLIT2 CHAT	6.95e-04	15	91	2	31812516
Pubmed	Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage.	ERBB3 VWF	6.95e-04	15	91	2	20457761
Pubmed	Embryonic and postnatal development of mouse olfactory tubercle.	RELN CHAT	7.93e-04	16	91	2	31200100
Pubmed	The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.	RNF2 PHC2	7.93e-04	16	91	2	12167701
Pubmed	Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome.	SFTPB LRP2	7.93e-04	16	91	2	15005800
Pubmed	Role of histone H2A ubiquitination in Polycomb silencing.	RNF2 PHC2	7.93e-04	16	91	2	15386022
Pubmed	A wide diversity of cortical GABAergic interneurons derives from the embryonic preoptic area.	RELN CHAT	8.98e-04	17	91	2	22090484
Pubmed	Dual origins of the mammalian accessory olfactory bulb revealed by an evolutionarily conserved migratory stream.	SLIT2 RELN	8.98e-04	17	91	2	23292680
Pubmed	A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development.	SLIT2 SLITRK5	8.98e-04	17	91	2	26102480
Pubmed	Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.	RNF2 PHC2	8.98e-04	17	91	2	22872859
Pubmed	In vivo visualization and molecular targeting of the cardiac conduction system.	SLIT2 SLITRK5	8.98e-04	17	91	2	35951416
Pubmed	ISL1-based LIM complexes control Slit2 transcription in developing cranial motor neurons.	SLIT2 CHAT	1.01e-03	18	91	2	27819291
Cytoband	8p23.1	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.58e-14	154	91	11	8p23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr8p23	FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10	1.58e-12	234	91	11	chr8p23
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	OR5T1 OR5T3 BTBD18 PRPF19 MYRF	6.38e-04	345	91	5	chr11q12
GeneFamily	WD repeat domain containing	FBXW8 PRPF19 ELP2 SPAG16 CFAP44	1.00e-03	262	53	5	362
GeneFamily	Ring finger proteins	RNF144B RNF2 MEX3D RNF213 RNF11	1.24e-03	275	53	5	58
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SELP VWF PLIN5 RMI2 ARHGAP8	7.26e-07	92	81	5	ed282f0f3da1593bdec5a2b20af5b8f058574167
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SELP VWF PLIN5 RMI2 ARHGAP8	7.26e-07	92	81	5	c5f30d58f235f7a72dfe63f58999c4680502576f
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SELP VWF PLIN5 RMI2 ARHGAP8	7.26e-07	92	81	5	27072dbf6819dca41e41267dc250abfaaf175b2f
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHIA LRRIQ1 SFTPB LRP2 LRRC43 CFAP44	8.94e-07	178	81	6	58857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHIA LRRIQ1 SFTPB LRP2 LRRC43 CFAP44	8.94e-07	178	81	6	8b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHIA LRRIQ1 SFTPB LRP2 LRRC43 CFAP44	8.94e-07	178	81	6	b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRIQ1 GAS2L2 PLIN5 SPAG16 LRRC43 CFAP44	1.31e-06	190	81	6	9ffd18ef358f8e32c610ab6420f479067c8ba44b
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRIQ1 GAS2L2 PLIN5 SPAG16 LRRC43 CFAP44	1.31e-06	190	81	6	3ef39d61c98de4e5df946b995847aa65eba6a4b6
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRIQ1 GAS2L2 PLIN5 SPAG16 LRRC43 CFAP44	1.35e-06	191	81	6	649fcb62ad15de2f83e61591e43923a717664ae7
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRIQ1 GAS2L2 PLIN5 SPAG16 LRRC43 CFAP44	1.35e-06	191	81	6	9621e22e14ea069f22713947c9faa2d882abe5fe
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF144B VWF GUCY1A1 GAS6 TSPAN7 NOTCH4	1.61e-06	197	81	6	61b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCell	3'-Child09-12-SmallIntestine-Endothelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP RELN VWF PLIN5 TSPAN7 NOTCH4	1.61e-06	197	81	6	86a02fd7b4762b3278e5e60b5483b5fc1206e597
ToppCell	5'-Adult-Distal_Rectal-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF144B VWF GUCY1A1 GAS6 TSPAN7 NOTCH4	1.66e-06	198	81	6	8d6b0b9da7c1e64155cbcbb04ad38d129a29030c
ToppCell	Endothelial_cells-Endothelial-A\|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id	SELP RNF144B NELL1 VWF TSPAN7 NOTCH4	1.71e-06	199	81	6	2a1424c61ddcd1fea9574f7a3ad1955387458130
ToppCell	distal-1-Endothelial-Artery\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP RNF144B VWF GAS6 TSPAN7 NOTCH4	1.71e-06	199	81	6	fd71d08f6de790a29c880d50d2ed0881952d7791
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELP RNF144B VWF CNKSR3 TSPAN7 NOTCH4	1.71e-06	199	81	6	9735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage-Macrophages-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELP RNF144B VWF CNKSR3 TSPAN7 NOTCH4	1.76e-06	200	81	6	e6d36be0c4c569e27303bb4e4f34cd2187e9759d
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Macrophages\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SELP RNF144B VWF CNKSR3 TSPAN7 NOTCH4	1.76e-06	200	81	6	c0c51719cf81512c50bfcc2fed883c867e522d2a
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELP RNF144B VWF CNKSR3 TSPAN7 NOTCH4	1.76e-06	200	81	6	758840c31f2ddd7ccf7bf13252ebb48d33e89479
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage-Macrophages\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELP RNF144B VWF CNKSR3 TSPAN7 NOTCH4	1.76e-06	200	81	6	c37fe06a94e5779c56e01389869bb432d3bbaebc
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLIT2 NELL1 GAS2L2 PLIN5 MEX3D	1.07e-05	159	81	5	c186bf05c61fac348cf41973827cced83fafd58a
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHIA SFTPB RMI2 LRP2 SLC5A1	1.31e-05	166	81	5	575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCell	facs-Aorta-Heart-24m-Endothelial-endocardial_endothelial_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP CHIA VWF ARHGAP8 USP27X	1.39e-05	168	81	5	edbab94f14e16a1a76546a18fe777a183080d1de
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 GAS2L2 PLIN5 LRRC43 CFAP44	1.60e-05	173	81	5	a7cc63bb3ab41feb9e4072700d44dbbbc62c47c6
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 GAS2L2 PLIN5 LRRC43 CFAP44	1.60e-05	173	81	5	e3e3a67a5a93ef4475224a256d45ae24526383cc
ToppCell	368C-Endothelial_cells-Endothelial-D\|368C / Donor, Lineage, Cell class and subclass (all cells)	SELP VWF CNKSR3 TSPAN7 NOTCH4	1.70e-05	175	81	5	c4088b5f9fa145869cf5dd8bee7680b1c8fada42
ToppCell	368C-Endothelial_cells-Endothelial-D-\|368C / Donor, Lineage, Cell class and subclass (all cells)	SELP VWF CNKSR3 TSPAN7 NOTCH4	1.70e-05	175	81	5	ca0d3e3a0a271cccdd3881b055fecb626712478d
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 LRRIQ1 GAS2L2 PLIN5 LRRC43	1.79e-05	177	81	5	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 LRRIQ1 GAS2L2 PLIN5 LRRC43	1.84e-05	178	81	5	b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 LRRIQ1 GAS2L2 PLIN5 LRRC43	1.84e-05	178	81	5	579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN VWF PLIN5 TSPAN7 ZP2	1.89e-05	179	81	5	1c0c0647a111f691dae55f4ed8c51006059ce020
ToppCell	368C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ERBB3 FAM193A SFTPB UBE3D NOTCH4	1.94e-05	180	81	5	eb5a57604c7f2ad256c300085dbf5069d0ae1ad0
ToppCell	368C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ERBB3 FAM193A SFTPB UBE3D NOTCH4	1.94e-05	180	81	5	ddba4dc3bbcfe4e4a22400be73bbc62d3ff27d3c
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SELP RNF144B VWF TSPAN7 NOTCH4	1.94e-05	180	81	5	5861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCell	facs-GAT-Fat-3m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 LRRIQ1 PLIN5 LRP2 SPAG16	1.99e-05	181	81	5	e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCell	facs-GAT-Fat-3m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 LRRIQ1 PLIN5 LRP2 SPAG16	1.99e-05	181	81	5	11cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCell	facs-GAT-Fat-3m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 LRRIQ1 PLIN5 LRP2 SPAG16	1.99e-05	181	81	5	5ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB3 GLDC PLIN5 MYRF F13B	2.05e-05	182	81	5	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRIQ1 PLIN5 LRP2 SPAG16 CFAP44	2.05e-05	182	81	5	587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	SELP RELN VWF TSPAN7 NOTCH4	2.05e-05	182	81	5	d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRIQ1 PLIN5 LRP2 SPAG16 CFAP44	2.05e-05	182	81	5	adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB3 GLDC PLIN5 MYRF F13B	2.05e-05	182	81	5	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB3 GLDC PLIN5 MYRF F13B	2.05e-05	182	81	5	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 PLIN5 LRP2 LRRC43 CFAP44	2.10e-05	183	81	5	6ca7c2d7c56e0f1b9038ba677b4c1c3dfd63bfce
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 PLIN5 LRP2 LRRC43 CFAP44	2.10e-05	183	81	5	18040d0653286071df959513c63d94b555a5d00a
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF GAS6 TSPAN7 ACSM6 NOTCH4	2.16e-05	184	81	5	16ed515fb673a9d6973133afcda0a3fba4a8d9dc
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.16e-05	184	81	5	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	COPD-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.21e-05	185	81	5	4abe04198ab5047c211f8d09cdb9650fa52a3cd6
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.21e-05	185	81	5	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	droplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP VWF TSPAN7 UTRN NOTCH4	2.27e-05	186	81	5	5d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCell	COPD-Endothelial-VE_Peribronchial\|COPD / Disease state, Lineage and Cell class	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.27e-05	186	81	5	23c7d0e8372a71546d687278b985f761d282f92f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SELP GUCY1A1 CNST BAMBI RNF11	2.33e-05	187	81	5	644d49bf66745d2e2d0f9bb3290d3e60c4ca7c4a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP VWF BTBD18 GAS6 TSPAN7	2.33e-05	187	81	5	3548a9914c2b2f5d805798ce22ab26eab6d03897
ToppCell	COPD-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.33e-05	187	81	5	be42ee71d3412bb1f52593d8814de85c354a0efa
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SELP GUCY1A1 CNST BAMBI RNF11	2.33e-05	187	81	5	854ef90afa59b18ee9f38cfb4659808b79c25202
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 LRRIQ1 SFTPB GLDC LRP2	2.33e-05	187	81	5	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	facs-Lung-EPCAM-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRIQ1 GAS2L2 SPAG16 LRRC43 CFAP44	2.33e-05	187	81	5	051b8c07d7489ce7576f6c57ce7008767ef76869
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SELP GUCY1A1 CNST BAMBI RNF11	2.33e-05	187	81	5	eac261f16d3a9e9213199872dffccb9f4e1d6f18
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.33e-05	187	81	5	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRIQ1 GAS2L2 SPAG16 LRRC43 CFAP44	2.33e-05	187	81	5	888856cde7a69ea2f14d590597e25b1af6383c51
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SELP GUCY1A1 CNST BAMBI RNF11	2.33e-05	187	81	5	ff84f75c10037f27c1f56eb1accd150cfe52f8e4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP VWF BTBD18 GAS6 TSPAN7	2.33e-05	187	81	5	f4de4b7af1fdfbd628b1f509c060c1079d2e5437
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP VWF BTBD18 GAS6 TSPAN7	2.33e-05	187	81	5	81754e965848b718be20ee97ce072ce426938a69
ToppCell	Control-Endothelial_cells-Arterial_endothelial_cells\|Control / group, cell type (main and fine annotations)	SELP RNF144B VWF TSPAN7 NOTCH4	2.33e-05	187	81	5	81affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VWF TSPAN7 ARHGAP8 UTRN NOTCH4	2.39e-05	188	81	5	5bc1537e079c7435196c163bff5f639ea392a33a
ToppCell	Control-Endothelial-VE_Peribronchial\|Control / Disease state, Lineage and Cell class	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.39e-05	188	81	5	f5b7dbc89f992c13280d36a34935be83906b1bc0
ToppCell	Control-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.45e-05	189	81	5	c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	SELP RNF144B VWF TSPAN7 NOTCH4	2.45e-05	189	81	5	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP VWF TSPAN7 UTRN NOTCH4	2.45e-05	189	81	5	9da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCell	PND10-Epithelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHIA SFTPB GAS6 LRP2 CFAP44	2.45e-05	189	81	5	89349e226a5512833a94b1bf68056a6985fe4afd
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN VWF PLIN5 TSPAN7 UTRN	2.52e-05	190	81	5	32400c62cb9de4c2b24af4206c21a0215ab12212
ToppCell	facs-Lung-nan-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRIQ1 GAS2L2 PLIN5 SPAG16 LRRC43	2.52e-05	190	81	5	e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN VWF PLIN5 TSPAN7 UTRN	2.52e-05	190	81	5	b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	RNF144B VWF GUCY1A1 UTRN NOTCH4	2.52e-05	190	81	5	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	droplet-Lung-3m-Epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CHIA LRRIQ1 SFTPB LRP2 CFAP44	2.52e-05	190	81	5	0725b79778232a57cc2c3214e0ecd62bac945063
ToppCell	COVID-19-Endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.52e-05	190	81	5	9fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCell	facs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRIQ1 GAS2L2 PLIN5 SPAG16 LRRC43	2.52e-05	190	81	5	fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN GUCY1A1 TSPAN7 UTRN NOTCH4	2.58e-05	191	81	5	79b399496bd7322a1d53c43378f48695fd09a5d9
ToppCell	facs-Trachea-24m-Endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN GUCY1A1 TSPAN7 UTRN NOTCH4	2.58e-05	191	81	5	9c6d5d045781c6506ae80e318427ef1e0d87f45c
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF GUCY1A1 GAS6 TSPAN7 NOTCH4	2.58e-05	191	81	5	adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP VWF TSPAN7 UTRN NOTCH4	2.58e-05	191	81	5	3307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN GUCY1A1 TSPAN7 UTRN NOTCH4	2.58e-05	191	81	5	1b1e943709d0c3283a980c7c965ef1f110506a29
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)\|343B / Donor, Lineage, Cell class and subclass (all cells)	SELP RNF144B VWF TSPAN7 NOTCH4	2.58e-05	191	81	5	27a532a35d9e8822014f581fd56c4ca62e39f8fe
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SELP RNF144B VWF TSPAN7 NOTCH4	2.58e-05	191	81	5	1dfcff08e01e6a695953334342bcfde04ba005ad
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN VWF PLIN5 ZP2 UTRN	2.65e-05	192	81	5	fa0ef05a32c661bdd59b5a9b6f75fd647ee937f3
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.65e-05	192	81	5	c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN VWF PLIN5 ZP2 UTRN	2.65e-05	192	81	5	4e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NELL1 ERBB3 LRRIQ1 GLDC LRP2	2.65e-05	192	81	5	b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP VWF GAS6 TSPAN7 NOTCH4	2.71e-05	193	81	5	c0f0052c24b7fe9e21d2bc6c38047a8e755f87b6
ToppCell	COPD-Endothelial-VE_Arterial\|COPD / Disease state, Lineage and Cell class	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.71e-05	193	81	5	1c701b6ab5f0f0239634adac94fa1c92bf3c36f4
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP VWF GAS6 TSPAN7 NOTCH4	2.71e-05	193	81	5	1e6e2d786511cc40241197368f5df20c20b882f3
ToppCell	IPF-Endothelial-VE_Arterial\|IPF / Disease state, Lineage and Cell class	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.71e-05	193	81	5	bf83b1fe9d38408f30eee4eb634341c04ef82791
ToppCell	COPD-Endothelial\|COPD / Disease state, Lineage and Cell class	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.71e-05	193	81	5	093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN VWF PLIN5 TSPAN7 ZP2	2.71e-05	193	81	5	ef007b736da56529ec628fc3df86a335e7ec3f18
ToppCell	IPF-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.71e-05	193	81	5	70a9aadda83a97e06e9bc2d1327ce60dd3c58767
ToppCell	IPF-Endothelial-VE_Venous\|IPF / Disease state, Lineage and Cell class	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.71e-05	193	81	5	29a655fa80feaabe846c90a28363b037e22d24ae
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP VWF GAS6 TSPAN7 NOTCH4	2.71e-05	193	81	5	682ce63b73a7d02eef240673db67058d7507f744
ToppCell	IPF-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	SELP VWF CNKSR3 TSPAN7 NOTCH4	2.71e-05	193	81	5	ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)\|390C / Donor, Lineage, Cell class and subclass (all cells)	SELP RNF144B VWF TSPAN7 NOTCH4	2.78e-05	194	81	5	f8a59bd4609d147d8a706bf606e9e8173c9992a3
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SELP RNF144B VWF TSPAN7 NOTCH4	2.78e-05	194	81	5	8c88a0ddd61ad900426e312ca4ab13061c0380b8
Disease	Thrombus	SELP VWF GUCY1A1 GAS6	6.44e-06	46	77	4	C0087086
Disease	Thrombosis	SELP VWF GUCY1A1 GAS6	8.31e-06	49	77	4	C0040053
Disease	Moyamoya disease (is_implicated_in)	GUCY1A1 RNF213	6.69e-05	5	77	2	DOID:13099 (is_implicated_in)
Disease	ductal carcinoma in situ (is_implicated_in)	SRC NOTCH4	1.40e-04	7	77	2	DOID:0060074 (is_implicated_in)
Disease	triglyceride change measurement, response to long-chain n-3 PUFA dietary supplementation	SLIT2 NELL1	1.86e-04	8	77	2	EFO_0007681, EFO_0009308
Disease	Colon Carcinoma	ERBB3 SRC	2.39e-04	9	77	2	C0699790
Disease	brain measurement, neuroimaging measurement	SLIT2 DIP2B NELL1 ERBB3 LRRIQ1 CNKSR3 TRIOBP	5.87e-04	550	77	7	EFO_0004346, EFO_0004464
Disease	Unipolar Depression	SELP NELL1 ERBB3 RELN HTR1A	5.92e-04	259	77	5	C0041696
Disease	brain connectivity measurement	SLIT2 NELL1 ERBB3 LRRIQ1 CNKSR3 TRIOBP	6.30e-04	400	77	6	EFO_0005210
Disease	Proteinuria	VWF LRP2	6.90e-04	15	77	2	HP_0000093
Disease	psoriasis	ERBB3 GUCY1A1 RMI2 LRRC43 NOTCH4	7.50e-04	273	77	5	EFO_0000676
Disease	Crohn's disease	NELL1 KSR1 UBE3D RMI2 MYRF NOTCH4	1.04e-03	441	77	6	EFO_0000384
Disease	primary ciliary dyskinesia (implicated_via_orthology)	SLIT2 GAS2L2	1.12e-03	19	77	2	DOID:9562 (implicated_via_orthology)
Disease	bipolar disorder (is_marker_for)	RELN VWF	1.12e-03	19	77	2	DOID:3312 (is_marker_for)
Disease	severe acute respiratory syndrome, COVID-19	KSR1 RELN GLDC CNKSR3 TSPAN7 ELP2	1.12e-03	447	77	6	EFO_0000694, MONDO_0100096
Disease	Depression, Bipolar	RELN HTR1A STARD9	1.17e-03	79	77	3	C0005587
Disease	Cardiac Hypertrophy	SRC GAS6 BAMBI	1.30e-03	82	77	3	C1383860
Disease	Cardiomegaly	SRC GAS6 BAMBI	1.30e-03	82	77	3	C0018800
Disease	rheumatoid arthritis	KSR1 ERBB3 FAM193A SRC MYRF NOTCH4	1.32e-03	462	77	6	EFO_0000685
Disease	diet measurement, fasting blood insulin measurement	HTR1A SPAG16	1.50e-03	22	77	2	EFO_0004466, EFO_0008111
Disease	diet measurement, HOMA-IR	HTR1A SPAG16	1.64e-03	23	77	2	EFO_0004501, EFO_0008111
Disease	susceptibility to plantar warts measurement	CFAP47 NOTCH4 PHC2	1.71e-03	90	77	3	EFO_0008406
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	SLIT2 SFTPB	1.79e-03	24	77	2	DOID:3827 (biomarker_via_orthology)
Disease	pulmonary embolism	CNKSR3 BANP	1.94e-03	25	77	2	EFO_0003827
Disease	optic disc size measurement	SELP LRRIQ1 LRP2 TRIOBP	2.06e-03	205	77	4	EFO_0004832
Disease	myeloperoxidase measurement	SIRPB2 NOTCH4	2.10e-03	26	77	2	EFO_0005243
Disease	antioxidant measurement	RNF2 SPAG16	2.26e-03	27	77	2	EFO_0005119
Disease	susceptibility to rheumatic fever measurement	SLIT2 RELN	2.43e-03	28	77	2	EFO_0008416
Disease	Seizures	HTR1A KARS1 GLDC CHAT	2.57e-03	218	77	4	C0036572

Protein segments in the cluster

Peptide	Gene	Start	Entry
CAIIPSDMLHISTNC	BANP	231	Q8N9N5
LCHMPTFCPETVLNV	ACSM6	291	Q6P461
SCHPECQPMEGTATC	ERBB3	551	P21860
MEPPHLVSCSVESAA	A4GNT	61	Q9UNA3
FMPDNIDPCLCTHLI	CHIA	41	Q9BZP6
SPMSHPESTLLIICE	CFAP44	626	Q96MT7
CSLSHILTCGIMDPP	FAM193A	216	P78312
STPCLPTAQACTMSH	FAM90A10	366	A6NDY2
DESFHCQHPPCRMSI	ATG4B	296	Q9Y4P1
FNMPTCVLHCLSPCL	ABHD8	291	Q96I13
STPCLPTAQACTMSH	FAM90A7	366	A6NKC0
VPLHSNEDMVCSVSP	PCDHGB6	771	Q9Y5F9
SPITCPDMVCLNHGT	RNF144B	71	Q7Z419
SCPMPHLACSSDAVE	MBD3L1	116	Q8WWY6
SRPCLPTAQACTMSH	FAM90A23	366	A8MXZ1
SRPCLPTAQACTMSH	FAM90A1	366	Q86YD7
SRPCLPTAQACTMSH	FAM90A22	366	A8MWA6
SRPCLPTAQACTMSH	FAM90A14	366	P0C7W9
PLCLEPCTLSFTEME	F13B	576	P05160
PLPVCRSSCDAMATH	FBXW8	571	Q8N3Y1
CMNPPHLAIITSFCK	KSR1	676	Q8IVT5
LHPCNILMCPHTCVT	DIP2B	926	Q9P265
SVNMTECVPVPSSEH	MEX3D	176	Q86XN8
QDHQPTPDSCIISMV	NUTF2	71	P61970
SDELMHLCHTPEPTC	LRP2	3061	P98164
STPCLPTAQACTMSH	FAM90A17	366	P0DV74
STPCLPTAQACTMSH	FAM90A16	366	P0DV73
STPCLPTAQACTMSH	FAM90A19	366	P0DV76
EMCPPLNCSEKDHIL	NELL1	366	Q92832
HENAPEPDSMTCCVS	LRRIQ1	716	Q96JM4
HLVQEECLPSMPSCQ	RELN	961	P78509
MSLICSISNEVPEHP	PRPF19	1	Q9UMS4
STPCLPTAQACTMSH	FAM90A8	366	A6NJQ4
CNMPPLLAISCSDTH	OR5T1	191	Q8NG75
PTRTELCQDSPMCTK	BTBD18	411	B2RXH4
SETDTIICPMCKAPE	C5orf60	276	A6NFR6
TTIPTLECCHEDMCN	BAMBI	91	Q13145
LDQMVQSLVSHCTCP	GAS2L2	206	Q8NHY3
SQDMDTCEDILPCVP	GAS6	271	Q14393
CMSPLAESSVIPCES	BORA	476	Q6PGQ7
LVLPFCESSCHMPTL	HTR1A	366	P08908
CEPLESPVHGSMDCS	SELP	386	P16109
MHEPSLCANVECPPA	CRIPAK	1	Q8N1N5
MVAPVLETSHVFCCP	ELP2	1	Q6IA86
LVPECLNTLCSPMHS	CCDC168	1406	Q8NDH2
LESLSCPKDMAPSHC	H6PD	81	O95479
SRPCLPTAQACTMSH	FAM90A5P	366	A8MXJ8
SEPSTPQEKHDCSLM	CFAP47	726	Q6ZTR5
MAIQSLHPCPSELCC	MFSD12	421	Q6NUT3
NCVSSIPDFPMHLAC	PPRC1	266	Q5VV67
SPRSLHSELMCPICL	RNF2	41	Q99496
EPLGSSPCCHQMDVQ	CNST	331	Q6PJW8
SPCCHQMDVQTDSPS	CNST	336	Q6PJW8
SRPCLPTAQACTMSH	FAM90A24P	366	P0C7X0
NEISSMECLCAHPPA	LRRC43	181	Q8N309
HVFCDMPPLLAISCS	OR5T3	206	Q8NGG3
MPPLLAISCSDTHTN	OR5T3	211	Q8NGG3
CPSCMEPVDAALLSS	RNF11	136	Q9Y3C5
VMEQIHSTFPSCCPN	UTRN	3411	P46939
CPPECPESLHDLMCQ	SRC	486	P12931
CSPEPCLQAVKMTDL	RMI2	111	Q96E14
CGTMSSPLQCIHSPD	SFTPB	366	P07988
CINPTFICDHPQIMS	KARS1	456	Q15046
SRPCLPTAQACTMSH	FAM90A12P	366	A8MX19
STPCLPTAQACTMSH	FAM90A9	366	A6NNJ1
SRPCLPTAQACTMSH	FAM90A13P	366	P0C7W8
SRPCLPTAQACTMSH	FAM90A26	366	D6RGX4
TMLDIPSEPCSLTIH	SUPT7L	51	O94864
SLCPSPDMQEFHSCK	STARD9	1356	Q9P2P6
LMPEKDSTFHLCLCP	NOTCH4	251	Q99466
SRPCLPTAQACTMSH	FAM90A15P	366	P0C7V4
MDSLHECPHIPTPVC	TRIOBP	1151	Q9H2D6
SIMPEPEHVIVACCN	CHAT	296	P28329
PVMSQCACLEEVHLP	CNK3/IPCEF1	201	G9CGD6
PVMSQCACLEEVHLP	CNKSR3	201	Q6P9H4
CCSLPAESLDAEVMP	PNMA5	126	Q96PV4
VSLESSNLCMPDLPH	RINL	106	Q6ZS11
MECPSCQHVSKEETP	RNF213	1	Q63HN8
MCSTMSAPTCLAHLP	SIRPB2	1	Q5JXA9
MENELPVPHTSSSAC	PHC2	1	Q8IXK0
PSPELCLVCEMSSLF	USP27X	116	A6NNY8
LGPSIPNAHSCEMCI	ZNF549	96	Q6P9A3
TDHSACSPVCPAGME	VWF	286	P04275
MHTCCPPVTLEQDLH	SLITRK5	1	O94991
LVPLFTDCTPETMCE	TMEM94	971	Q12767
PELSPVEMCCVSSDN	UBE3D	181	Q7Z6J8
SCVSMQPHKDILVSC	SPAG16	356	Q8N0X2
MEDTPPSLSCSDCQR	ZNF646	1	O15015
QSFMAPSCSVLHCPA	SLIT2	261	O94813
VTFSCCRMPPSHELD	ARHGAP8	36	P85298
MECPHLSSSVCIAPD	USP3	1	Q9Y6I4
LSMCQIIHSEEPSPC	ZNF70	101	Q9UC06
MSPHPEAITDCVTLN	ZNF510	1	Q9Y2H8
IDHMQCGVTPTAPAC	PLIN5	241	Q00G26
CMEPSNCPTIICGVH	SLC5A1	511	P13866
LEHGIPPSCCMNETD	TSPAN7	166	P41732
CAPDPVTCNATHMTL	ZP2	261	Q05996
STPCLPTAQACTMSH	FAM90A18	366	P0DV75
VEVSLMPPCFHNDCS	GUCY1A1	231	Q02108
QHLVCTCPPMEVYES	GLDC	996	P23378
VRTLDMCSSHPCPVI	MYRF	871	Q9Y2G1