Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainRNaseH-like_dom

ZBED4 KIAA1586 REV3L

7.41e-0469483IPR012337
Domain-

MSH6 SMC1A GBP2 AK6 MCM7 PFKFB3 GNAS

2.79e-037464873.40.50.300
DomainJMJC

PHF2 KDM8

3.05e-0332482PS51184
DomainJmjC_dom

PHF2 KDM8

3.05e-0332482IPR003347
DomainJmjC

PHF2 KDM8

3.25e-0333482SM00558
DomainP-loop_NTPase

MSH6 SMC1A GBP2 AK6 MCM7 PFKFB3 GNAS

5.63e-03848487IPR027417
DomainZinc_finger_PHD-type_CS

PHF2 JADE3

1.21e-0265482IPR019786
Pubmed

Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C.

GNAS ADGRV1

6.32e-06351224191038
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PHF2 ZBED4 DEPDC5 ADGRV1

1.57e-051025149734811
Pubmed

Direct interaction between cohesin complex and DNA replication machinery.

SMC1A MCM7

4.41e-05751216438930
Pubmed

MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation.

MSH6 SMC1A

5.87e-05851214657349
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

PPP4R3B MSH6 DFFA SMC1A MCM7 PFKFB3 GNAS GDI1 UNC79

9.31e-05128451917353931
Pubmed

Mechanism of glycyrrhizic acid inhibition of Kaposi's sarcoma-associated herpesvirus: disruption of CTCF-cohesin-mediated RNA polymerase II pausing and sister chromatid cohesion.

SMC1A MCM7

9.42e-051051221880767
Pubmed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

SELP VPS33B MCM7 KDM8 GNAS GDI1 CCDC136

1.00e-0474251726871637
Pubmed

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint.

MSH6 SMC1A

1.15e-041151211877377
Pubmed

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.

DEPDC5 WDR24

1.15e-041151223723238
Pubmed

Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes.

MSH6 SMC1A

1.38e-041251216391231
Pubmed

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.

DEPDC5 WDR24

1.38e-041251225263562
Pubmed

Structure of the nutrient-sensing hub GATOR2.

DEPDC5 WDR24

1.63e-041351235831510
Pubmed

Ring domains are essential for GATOR2-dependent mTORC1 activation.

DEPDC5 WDR24

2.19e-041551236528027
Pubmed

SZT2 dictates GATOR control of mTORC1 signalling.

DEPDC5 WDR24

2.50e-041651228199315
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

MSH6 SMC1A REV3L

2.89e-048751317148452
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PHF2 SMC1A PPP1R16B ADGRV1

3.36e-0422551412168954
Pubmed

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.

DEPDC5 WDR24

3.94e-042051228199306
Pubmed

Polymorphisms in the platelet-specific collagen receptor GP6 are associated with risk of nonfatal myocardial infarction in Caucasians.

SELP THBS4

4.35e-042151220227257
Pubmed

SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.

MSH6 MCM7

4.35e-042151224958773
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

PHF2 SMC1A KDM8 PDZRN3

5.00e-0425051433536335
Pubmed

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation.

SMC1A MCM7

5.70e-042451218425126
Pubmed

Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human.

MST1R GNAS

5.70e-04245122902634
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

PHF2 SMC1A PFKFB3 ZNF654

6.85e-0427251431010829
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MSH6 THBS4 ZBED4 TM2D2 KDM8 REV3L

7.05e-0473651629676528
Pubmed

UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target.

MSH6 SMC1A

8.93e-043051232867711
Pubmed

Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.

MSH6 SMC1A MCM7

9.53e-0413151334551306
Pubmed

TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin.

MSH6 SMC1A

9.54e-043151226095369
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

PHF2 MSH6 SNRNP48 ZBED4 SACS SMC1A SMARCD3

9.70e-04108251738697112
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PPP4R3B JADE3 VPS50 DEPDC5 ADGRV1

1.05e-0352951514621295
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

PHF2 MSH6 VPS50 SMARCD3 REV3L LTBP4 PDZRN3

1.16e-03111651731753913
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

PPP4R3B MSH6 DFFA SMC1A GBP2 MCM7 GDI1 TSEN2

1.18e-03145551822863883
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

MSH6 VPS33B SMC1A VPS50 MCM7

1.36e-0356051535241646
Pubmed

A Novel Mechanism for NF-κB-activation via IκB-aggregation: Implications for Hepatic Mallory-Denk-Body Induced Inflammation.

SMC1A MCM7

1.36e-033751232912968
Cytoband5q13

THBS4 ADGRV1

2.76e-04225125q13
GeneFamilyPHD finger proteins|Lysine demethylases

PHF2 KDM8

7.67e-0424312485
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

SACS PPP1R16B MCM7

3.61e-03181313694
GeneFamilyPHD finger proteins

PHF2 JADE3

1.04e-029031288
CoexpressionGSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN

MSH6 CCRL2 PFKFB3 TNFAIP6 TEX14

3.95e-05196515M5849
CoexpressionGSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP

MSH6 CCRL2 GBP2 PFKFB3 TNFAIP6

4.04e-05197515M5867
CoexpressionGSE21033_CTRL_VS_POLYIC_STIM_DC_6H_UP

PHF2 SACS PFKFB3 TEX14 ZNF654

4.24e-05199515M7712
CoexpressionGSE25088_WT_VS_STAT6_KO_MACROPHAGE_DN

SELP MSH6 KANK1 JADE3 PRODH

4.24e-05199515M8031
CoexpressionAtlasdev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

MSH6 VPS50 MCM7 HERC3 LRRN4 EPB41L4A

2.43e-05258486gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k2_1000
CoexpressionAtlasDevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#1_top-relative-expression-ranked_1000

SNRNP48 TM2D2 VPS33B MCM7 TNFAIP6 PRODH WDR24

3.65e-05412487gudmap_developingKidney_e12.5_renal vesicle_1000_k1
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NBPF19 FNDC3B CCRL2 PFKFB3 TNFAIP6

2.24e-0618551542690b95e2e7d56c822211bb1150acb787cfe2e8
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNDC3B CCRL2 GBP2 PFKFB3 TNFAIP6

2.62e-061915150b296404ebad0aadb75737f8c0462ec6934fc8bb
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FNDC3B CCRL2 GBP2 PFKFB3 TNFAIP6

3.21e-061995159da8b48ec1c1c105fcbab6ae8f08166e7d5e8a35
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAG KANK1 TNFAIP6 ADGRV1

2.49e-05148514d60f93311cfa718d026a0dbf61771bbbcbb79146
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAG KANK1 TNFAIP6 ADGRV1

2.49e-0514851444128692824ca419fface0af41099c17135933ce
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAG KANK1 TNFAIP6 ADGRV1

2.63e-05150514b30f52b94ce772632a1f2f5e0837db876cf92651
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAG KANK1 TNFAIP6 ADGRV1

2.63e-0515051405b9a9cbc5a95cdaf45d5f173e132acd4da9aa8a
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)

NBPF19 CCRL2 SMARCD3 TNFAIP6

3.46e-051615141b5ebc82ee6166ecc2984648565f334cd69b636b
ToppCelldroplet-Heart-nan-24m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG9B KANK1 PPP1R16B LTBP4

3.46e-05161514eb546d5065ac506405d240f9a1f55f2122d0c368
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP PPP1R16B GBP2 DEPDC5

3.99e-05167514774f3264318b002d0df5d06d41d645366038d0bf
ToppCell356C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MST1R JADE3 PPP1R16B PRODH

4.18e-0516951444d201361eb497222a4972a0e10bac1e05dcfd0a
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP SACS JADE3 LTBP4

4.28e-0517051450c6c571591aa4b218caefe5778c570c809f567e
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP SACS JADE3 LTBP4

4.28e-051705148fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP SACS JADE3 LTBP4

4.28e-051705143232db50b1a40f861e981a1b9c9073b81af9f832
ToppCellFLU-Healthy-3|FLU / Virus stimulation, Condition and Cluster

MSH6 TMED7 SMARCD3 CCDC136

4.58e-0517351432b8e5b400885dbeba57a7cb2c18d882664dc285
ToppCellFLU-Healthy-3|Healthy / Virus stimulation, Condition and Cluster

MSH6 TMED7 SMARCD3 CCDC136

4.58e-0517351426e89ac86922f1cd0100cf4d1cce37e74dd31c88
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

NBPF19 THBS4 LTBP4 PDZRN3

4.79e-05175514f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP KANK1 EPB41L4A LTBP4

6.07e-05186514c116cc9f41971622264434ebe29d18e719b0ae19
ToppCellNS-moderate-d_0-4-Myeloid-Non-resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCRL2 GBP2 PFKFB3 TNFAIP6

6.20e-05187514fcc32dbc9c5ae6176f154715a3e73aa32d78ad64
ToppCelldroplet-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP PPP1R16B GBP2 EPB41L4A

6.20e-0518751464dd28b23eda7dfb7fd069be2742de7bad0fd87a
ToppCelldroplet-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP PPP1R16B GBP2 EPB41L4A

6.20e-05187514b535d5447bf15e95dcf025a0a455628b956fc857
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG PPP1R16B TNFAIP6 ADGRV1

6.46e-05189514bab0fe55643d3ee750355a32b1ff6634fa5cf88d
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FNDC3B CCRL2 PFKFB3 TNFAIP6

6.59e-05190514212f0d9defcc3174e225cc3d90e7814e238794b6
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP ATG9B PPP1R16B PFKFB3

6.59e-051905142655df8c0883dd811fa7617301f9c4b0a4dd55ec
ToppCellControl-Myeloid-MoAM5,_CCL3L1|Control / Condition, Lineage and Cell class

NBPF19 KANK1 PFKFB3 TNFAIP6

7.15e-05194514a1dd264822de83a0ffaf89ca4707c6a76809359e
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SELP PPP1R16B CCRL2 THSD7B

7.29e-05195514ca2cf2c10db1ad17aa0a2e30aa7079a7ad751ea6
ToppCellCF-Myeloid|CF / Disease state, Lineage and Cell class

FNDC3B CCRL2 PFKFB3 TNFAIP6

7.29e-05195514ecf604de496f389a49429d0bb211e1db6019cc8b
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD7B LTBP4 PDZRN3 CCDC136

7.29e-05195514d32716a12014522492becbde1088dc1106308490
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD7B LTBP4 PDZRN3 CCDC136

7.29e-05195514b913d5df50c88a3a255f516a1aa42419c6701e1e
ToppCell343B-Myeloid-Monocyte-CD14+_Monocyte|343B / Donor, Lineage, Cell class and subclass (all cells)

NBPF19 CCRL2 PFKFB3 TNFAIP6

7.29e-05195514b5ee368c97113432fc8fe742654cd538558f327c
ToppCell10x5'-Lung-Myeloid_Mac-Intermediate_macrophages|Lung / Manually curated celltypes from each tissue

FNDC3B CCRL2 PFKFB3 TNFAIP6

7.44e-05196514fede2c605f7581ce2ea7a284cffffa1a3970d811
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FNDC3B CCRL2 PFKFB3 TNFAIP6

7.44e-05196514d9b5eaca4089d5337f1175a663418c9c675cdd87
ToppCell(3)_MNP-(3)_Monocyte|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

NBPF19 CCRL2 PFKFB3 TNFAIP6

7.44e-0519651483af2eb1c28dfe7678d972be1d6d358c4a94731d
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NBPF19 CCRL2 PFKFB3 TNFAIP6

7.44e-05196514ff88e5b919b1be93159ad2200a7786d1c5272724
ToppCellBL-critical-LOC-Myeloid|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FNDC3B CCRL2 PFKFB3 TNFAIP6

7.58e-05197514932a7fae4979b561688e6222505df0f4e510ab11
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNDC3B CCRL2 PFKFB3 TNFAIP6

7.58e-0519751459aa4a31674125ae422450aee45db3ced5c405d3
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FNDC3B CCRL2 PFKFB3 TNFAIP6

7.58e-05197514037f5f26fa66818baa35846aa96336155e8a6f45
ToppCellILEUM-inflamed-(3)_MNP-(3)_Inf._Macrophages|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FNDC3B CCRL2 GBP2 TNFAIP6

7.73e-05198514ebc064dede536eda7715af0675fd4e657ff4ac5d
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FNDC3B CCRL2 PFKFB3 TNFAIP6

7.73e-05198514ecd93e28bae4152467f6d6621cffc73c301c9795
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

TNFAIP6 REV3L LTBP4 PDZRN3

7.89e-05199514fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

NBPF19 ADGRV1 PDZRN3 PRODH

8.04e-0520051416f468217427921fa18c6d078ffa990eb019b257
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Monocytic-Monocyte_CD14|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NBPF19 CCRL2 PFKFB3 TNFAIP6

8.04e-0520051454221271becd02a4ffa826e06c8e76fcd2651d50
ToppCellMacroglial-Astrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

NBPF19 ADGRV1 PDZRN3 PRODH

8.04e-05200514941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

NBPF19 ADGRV1 PDZRN3 PRODH

8.04e-05200514d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

NBPF19 ADGRV1 PDZRN3 PRODH

8.04e-05200514f861509b54185d89931db64da1b9d81986cc7938
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

NBPF19 ADGRV1 PDZRN3 PRODH

8.04e-052005140442894c39eec69850c090957a5dc7bcecd21e04
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

NBPF19 ADGRV1 PDZRN3 PRODH

8.04e-0520051401819446deeab9054f5cfe889d53bb49d137dbc0
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

MAG TNFAIP6 ADGRV1

3.10e-0411551315b2c11225802cc15c01165d84a755432f02d82f
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MAG TNFAIP6 ADGRV1

3.68e-041225132880f25d10a7765e55a2aa20c7a6ef74cea19c4d
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MAG TNFAIP6 ADGRV1

3.68e-04122513cffd7730bda90828efc0def452cabb44cf93ab48
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MST1R LRRN4 THSD7B

3.68e-0412251337612ad087d9c11d4a3466244ab36224de31930b
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MAG TNFAIP6 ADGRV1

3.68e-04122513ecd0e54dd829201290212ea2ff7c8e7eec19c0e9
ToppCellPosterior_cortex-Macroglia-OLIGODENDROCYTE|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MAG TNFAIP6 ADGRV1

3.86e-041245139f169fa17be1842a6bd83778ff30465a740edd5f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NBPF19 FNDC3B TNFAIP6

4.44e-04130513793c42602dde22da0715a5304ea70d791fdd5354
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Serpinb1a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAG TNFAIP6 ADGRV1

5.17e-04137513ca8fdbe66a854e6283b22179ec9359ea9e86cd8e
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE|Hippocampus / BrainAtlas - Mouse McCarroll V32

MAG TNFAIP6 ADGRV1

5.17e-041375135e97480f014f1d9267e8126f1d0e58acd22f36aa
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Serpinb1a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAG TNFAIP6 ADGRV1

5.39e-04139513789edd3c98e7c5c1cc402c780fded9a9dfd1dfb8
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THBS4 TNFAIP6 GNAS

7.12e-0415351361fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SELP ATG9B PPP1R16B

7.40e-04155513babcb9e548f04ace8157d506d27c5941c692c491
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

KANK1 ADGRV1 PRODH

7.96e-041595138680b054622f573a82b1625fb93c2d5db81d1034
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP2 PFKFB3 TNFAIP6

8.11e-041605132586035a1380bc56814a6db0ca773ad835666042
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GBP2 PFKFB3 TNFAIP6

8.11e-041605133b5a335786165391fe983ff0585cd508733793aa
ToppCellEntopeduncular|World / BrainAtlas - Mouse McCarroll V32

MAG KANK1 TNFAIP6

8.11e-04160513833763c8608de4ee6003b8fb682aa9c83d7dea9b
ToppCellBrain_organoid-organoid_Velasco_nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

PPP4R3B AK6 ADGRV1

8.26e-041615132de213169fe1965ceaea545297228117c81d9909
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TM2D2 AK6 CCDC136

8.56e-04163513ce07bc424ef99c547588b07f5c8b39ff0773ca9b
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JADE3 EPB41L4A PDZRN3

9.02e-0416651311b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JADE3 EPB41L4A PDZRN3

9.02e-04166513fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELP KANK1 LTBP4

9.18e-04167513f01b96173deda0239fa482989873cf308e49d48c
ToppCellThalamus-Macroglia-POLYDENDROCYTE|Thalamus / BrainAtlas - Mouse McCarroll V32

MAG KANK1 TMED7

9.18e-041675131e144c03409df94ccd39760842590e8ea7487e29
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELP KANK1 LTBP4

9.18e-041675135fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

SELP THBS4 PPP1R16B

9.18e-04167513d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCellVE-Treg-exh_CD4|VE / Condition, Cell_class and T cell subcluster

SELP TM2D2 CCDC136

9.18e-041675131036ac1ef9440612500137af9d1929672b077e4d
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG MST1R THBS4

9.18e-04167513f5bffa77061baec0ba87bd688a047595f32534db
ToppCellCOVID-19-Myeloid-MoAM5,_CCL3L1|Myeloid / Condition, Lineage and Cell class

NBPF19 TNFAIP6 UNC79

9.34e-04168513ea465152ea31391b63c02425beafa9a4f51f6703
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELP GBP2 LTBP4

9.50e-0416951358136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCellFrontal_cortex-Neuronal-Inhibitory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ATG9B GNAS CCDC136

9.50e-0416951378eb70dd916724e476eabccf18fb7fcec4210308
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

REV3L LTBP4 PDZRN3

9.50e-04169513c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELP GBP2 LTBP4

9.50e-0416951304c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell343B-Myeloid-Monocyte-CD14+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

NBPF19 TNFAIP6

9.56e-044051255acdee7651d5b2bf8f37a79d13e9f4ea7c79eb7
ToppCellfacs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP DFFA KDM8

9.66e-0417051312203d4410f38cc933d9f160b5fb76828df94119
ToppCellfacs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP DFFA KDM8

9.66e-04170513f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCell356C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

JADE3 PPP1R16B PRODH

9.66e-04170513513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FNDC3B GBP2 PFKFB3

9.83e-041715132b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PFKFB3 TSEN2 PRODH

9.83e-04171513effcc4b6d26eafc2ca6fa08b6fee2689eff48f0f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FNDC3B GBP2 PFKFB3

9.83e-04171513dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KANK1 ADGRV1 PRODH

9.99e-0417251355fba5ce0ead1114e1a76f67ad68432c6bac90e5
ToppCell343B-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MAG CCRL2 TNFAIP6

9.99e-04172513709c6b77a7a52b873eefb6caca28a41291d384af
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MST1R THBS4 TNFAIP6

9.99e-04172513c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCell343B-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MAG CCRL2 TNFAIP6

9.99e-04172513eb199c279fe8a2551121db37e9556893197d33ff
ToppCelldroplet-Limb_Muscle-nan-24m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R16B GBP2 TNFAIP6

9.99e-04172513770e4c5467ef2eaddf883723fb0aa1226973b000
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CCRL2 GBP2 TEX14

9.99e-0417251353dbfe1ac658fd94370cf8e745048cb67fda1daf
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MST1R THBS4 TNFAIP6

9.99e-04172513bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRRN4 THSD7B UNC79

1.02e-031735130a355386210a13927ea29b10b64cb059459952d4
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

ZBED4 SMARCD3 ADGRV1

1.02e-0317351342c911ed16fabdabef063830e8407192d8bde950
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRRN4 THSD7B UNC79

1.02e-031735133678b300cad4effd7f49bfb043305ed512693848
ToppCellFrontal_cortex-Macroglia|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MAG KANK1 TNFAIP6

1.02e-03173513ac70145e093ef0df43811e7c67a865ccdd45a5e3
ToppCellcritical-Epithelial-unknown_epithelial|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PFKFB3 TNFAIP6 TEX14

1.02e-031735134144b1cdefa8c37b6ac7a6d249fa5292ffb2b8b2
ToppCellCOVID-19-Myeloid-MoAM5,_CCL3L1|COVID-19 / Condition, Lineage and Cell class

NBPF19 CCRL2 TNFAIP6

1.02e-03173513502f888b7684ed39f5c577eedcacf673ae81d39e
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

SACS THSD7B PDZRN3

1.02e-03173513a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRN4 THSD7B UNC79

1.03e-03174513d9489c4196d103ead8cb6279492bbe563a222e45
ComputationalGenes in the cancer module 208.

SELP PPP1R16B GBP2 TNFAIP6 UNC79

3.45e-05124335MODULE_208
ComputationalGenes in the cancer module 171.

SELP PPP1R16B GBP2 TNFAIP6 UNC79

5.76e-05138335MODULE_171
ComputationalImmune response and Ag processing and presentation.

PPP1R16B GBP2 TNFAIP6 UNC79

5.66e-04126334MODULE_345
ComputationalGenes in the cancer module 292.

PPP1R16B GBP2 TNFAIP6 UNC79

7.55e-04136334MODULE_292
ComputationalGenes in the cancer module 436.

PPP1R16B GBP2 TNFAIP6 UNC79

7.97e-04138334MODULE_436
ComputationalNeighborhood of SMC1L1

MSH6 SMC1A MCM7

8.81e-0462333MORF_SMC1L1
DrugDSGG

MAG SELP ZNF654

5.14e-0616493CID000126334
DiseaseArsenic Induced Polyneuropathy

CCRL2 PFKFB3 TNFAIP6

1.34e-0462473C0751852
DiseaseArsenic Encephalopathy

CCRL2 PFKFB3 TNFAIP6

1.34e-0462473C0751851
DiseaseArsenic Poisoning

CCRL2 PFKFB3 TNFAIP6

1.34e-0462473C0311375
DiseaseArsenic Poisoning, Inorganic

CCRL2 PFKFB3 TNFAIP6

1.34e-0462473C0274861
DiseaseNervous System, Organic Arsenic Poisoning

CCRL2 PFKFB3 TNFAIP6

1.34e-0462473C0274862
DiseaseDermatologic disorders

CCRL2 PFKFB3 TNFAIP6

2.36e-0475473C0037274
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

MSH6 THBS4 THSD7B REV3L UNC79 ZNF654 PDZRN3

2.59e-04801477EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseCholestasis

KANK1 TMED7 GNAS

7.25e-04110473C0008370

Protein segments in the cluster

PeptideGeneStartEntry
LAPEDEYDVLIEGEL

CCRL2

6

O00421
VYIAVCDDDLPEPDE

ADGRV1

96

Q8WXG9
DGTIVDDDDYFLCLP

DFFA

66

O00273
VEDDLDLVGAPEYEC

RBFA

301

Q8N0V3
TDADYLGIPVDECER

PDZRN3

631

Q9UPQ7
GYDEEYDCPILDEDR

AK6

46

Q9Y3D8
YDCPILDEDRVVDEL

AK6

51

Q9Y3D8
TEGCYDLLPEADIDR

DEPDC5

771

O75140
ELEEVTPAEDGVYAC

MAG

291

P20916
LLDYPGEDVEETFCL

HERC3

841

Q15034
IPDYCSLGDGEEEEI

KDM8

291

Q8N371
PVLEYIDLVCGDDEN

KIAA1586

41

Q9HCI6
LNEIDAGVCEELTYE

PFKFB3

321

Q16875
SDDECDVIEYPLEEE

KANK1

1021

Q14678
ELEVDGEPITADDYL

GBP2

186

P32456
LVGLVDYPDDEEEDE

PPP4R3B

821

Q5MIZ7
DDFIPNDILIGCEEE

MSH6

1106

P52701
VALYVDLDDVAEDDP

MCM7

46

P33993
YDLCEDEPTLDVIET

PPP1R16B

171

Q96T49
TLCVLEEEPLDAYPD

FNDC3B

866

Q53EP0
ADLELSLPECLEYEE

GNAS

91

O95467
IPEQDYERLEDCDPE

ATG9B

146

Q674R7
GPECEYVRECGELEL

SELP

191

P16109
AEPYEELEAEECGIL

LTBP4

1526

Q8N2S1
VAISDLYEPIDDGCE

GDI1

381

P31150
AVPEEFYCEVLLLDE

EPB41L4A

6

Q9HCS5
ELYEVIGCVPVDDLE

SACS

3461

Q9NZJ4
ATLEYLDLDDCGIID

PRAMEF26

256

H0Y7S4
EGLGIEYDEDVICDV

JADE3

191

Q92613
EGEIPVLLLDDYSEE

LRRN4

516

Q8WUT4
RGPDHEYVLVEEAEC

TSEN2

251

Q8NCE0
IYSGCLILEDDIEEP

TEX14

631

Q8IWB6
GVEEEEAPDIDIYHC

PHF2

36

O75151
VEEPEVLQDSLDGCY

NBPF19

3771

A0A087WUL8
ILDYGVEEDLSPEEA

PRODH

141

O43272
ACYDIDVEVEEPLKG

SMARCD3

356

Q6STE5
GEVLLPALYEEEEEE

CCDC136

6

Q96JN2
CGKDVDIDSYPDEEL

THBS4

461

P35443
LEEEDYPGAIQLCLE

VPS50

191

Q96JG6
ILCSYLPDEFIECED

TM2D2

71

Q9BX73
DLEDDPGCLADYVEI

TNFAIP6

181

P98066
DGELVDVACEDLELY

REV3L

1826

O60673
YDVDCRLEDPDGKVL

TMED7

71

Q9Y3B3
KPLTECGDDYEEEED

ZNF654

691

Q8IZM8
EALIEIDYGDLCEDL

SMC1A

976

Q14683
GDVEGEEDELYLLDP

WDR24

541

Q96S15
DLYPLVETELCPCDE

THSD7B

911

Q9C0I4
TEPELGDYRELVLDC

MST1R

286

Q04912
GEEEAAEDEVVICPY

SNRNP48

46

Q6IEG0
VLEEEGIYGDVSCDE

VPS33B

126

Q9H267
CGAILEEYDEETLGL

UNC79

2011

Q9P2D8
LAYLEEEVLEHSCDP

ZBED4

1086

O75132