Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

TRPM6 CACNA1A VMP1 CACNA1E ABCC1 ABCC4 SLC16A13 HTR1B XKR9 SLC22A11 BEST3 SLC35F1 SLC15A3 XKR4 TMC3 ATP13A2 AQP5 SLC45A4 ITPR1 ITPR2 SLC5A3 ZACN ABCG1 SLC12A2 TRPM3 P2RX2 CNGB3 KCNS1 SERINC3 TRPV4 KCNK6 SLC39A14 SLC26A11 MFSD10

9.84e-15128911234GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

TRPM6 CACNA1A CACNA1E ABCC1 ABCC4 SLC16A13 HTR1B SLC22A11 BEST3 SLC35F1 SLC15A3 TMC3 ATP13A2 AQP5 SLC45A4 ITPR1 ITPR2 SLC5A3 ZACN ABCG1 SLC12A2 TRPM3 P2RX2 CNGB3 KCNS1 SERINC3 TRPV4 KCNK6 SLC39A14 SLC26A11 MFSD10

2.25e-13118011231GO:0022857
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

TRPM6 CACNA1A CACNA1E HTR1B BEST3 SLC15A3 TMC3 ATP13A2 SLC45A4 ITPR1 ITPR2 SLC5A3 ZACN SLC12A2 TRPM3 P2RX2 CNGB3 KCNS1 TRPV4 KCNK6 SLC39A14 SLC26A11

4.53e-1079311222GO:0015075
GeneOntologyMolecularFunctionchannel activity

TRPM6 CACNA1A CACNA1E HTR1B BEST3 TMC3 AQP5 ITPR1 ITPR2 ZACN SLC12A2 TRPM3 P2RX2 CNGB3 KCNS1 TRPV4 KCNK6 SLC26A11

7.79e-1052511218GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TRPM6 CACNA1A CACNA1E HTR1B BEST3 TMC3 AQP5 ITPR1 ITPR2 ZACN SLC12A2 TRPM3 P2RX2 CNGB3 KCNS1 TRPV4 KCNK6 SLC26A11

8.02e-1052611218GO:0022803
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

TRPM6 CACNA1A CACNA1E ABCC1 ABCC4 HTR1B SLC22A11 BEST3 SLC15A3 AQP5 SLC45A4 ITPR1 ITPR2 SLC5A3 SLC12A2 TRPM3 KCNS1 TRPV4 KCNK6 SLC39A14 SLC26A11

1.23e-0975811221GO:0015318
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TRPM6 CACNA1A CACNA1E HTR1B SLC15A3 ATP13A2 SLC45A4 ITPR1 ITPR2 SLC5A3 ZACN SLC12A2 TRPM3 P2RX2 CNGB3 KCNS1 TRPV4 KCNK6 SLC39A14

4.96e-0966411219GO:0008324
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

NPR1 TPRA1 DRD2 HTR1B TRHR SIGMAR1 OR2T7 FPR1 INSRR GPR141 TAAR3P GPR87 GRM6 GPR179 CCR2 OR2W3 GPR161 OR51B5 BMPR1A ZACN OR4P4 OR14A2 FCER1G P2RX2 GLP1R TRPV4 TM2D1

4.99e-09135311227GO:0004888
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TRPM6 CACNA1A CACNA1E HTR1B BEST3 TMC3 ITPR1 ITPR2 ZACN TRPM3 P2RX2 CNGB3 KCNS1 TRPV4 KCNK6 SLC26A11

5.90e-0945911216GO:0005216
GeneOntologyMolecularFunctionG protein-coupled receptor activity

NPR1 TPRA1 DRD2 HTR1B TRHR SIGMAR1 OR2T7 FPR1 GPR141 TAAR3P GPR87 GRM6 GPR179 CCR2 OR2W3 GPR161 OR51B5 OR4P4 OR14A2 GLP1R TM2D1

1.83e-0888411221GO:0004930
GeneOntologyMolecularFunctiongated channel activity

CACNA1A CACNA1E HTR1B BEST3 TMC3 ITPR1 ITPR2 ZACN P2RX2 CNGB3 KCNS1 TRPV4 KCNK6

4.88e-0833411213GO:0022836
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPM6 CACNA1A CACNA1E HTR1B ITPR1 ITPR2 ZACN TRPM3 P2RX2 CNGB3 KCNS1 TRPV4 KCNK6

6.66e-0834311213GO:0005261
GeneOntologyMolecularFunctioncalcium channel activity

TRPM6 CACNA1A CACNA1E HTR1B ITPR1 ITPR2 TRPM3 TRPV4

6.61e-071291128GO:0005262
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TRPM6 CACNA1A CACNA1E HTR1B ITPR1 ITPR2 SLC5A3 SLC12A2 TRPM3 KCNS1 TRPV4 KCNK6 SLC39A14

2.10e-0646511213GO:0046873
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPM6 CACNA1A CACNA1E HTR1B ITPR1 ITPR2 TRPM3 TRPV4

2.17e-061511128GO:0015085
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TRPM6 CACNA1A CACNA1E HTR1B SLC15A3 SLC45A4 ITPR1 ITPR2 SLC5A3 SLC12A2 TRPM3 KCNS1 TRPV4 KCNK6 SLC39A14

2.26e-0662711215GO:0022890
GeneOntologyMolecularFunctionATPase-coupled lipid transmembrane transporter activity

ABCC1 ABCC4 ABCG1

1.41e-0591123GO:0034040
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1A CACNA1E HTR1B

1.41e-0591123GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1A CACNA1E HTR1B

1.41e-0591123GO:0099626
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCC1 ABCC4 SLC16A13 SLC22A11 SLC15A3 ATP13A2 SLC45A4 SLC5A3 ABCG1 SLC12A2 SLC39A14 SLC26A11

1.53e-0547711212GO:0022804
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

ABCC1 ABCC4 SLC15A3

9.12e-05161123GO:0035673
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2

9.32e-0531122GO:0005220
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

BEST3 ITPR1 ITPR2 ZACN P2RX2 CNGB3 KCNK6

1.09e-041931127GO:0015276
GeneOntologyMolecularFunctionlipid transporter activity

VMP1 ABCC1 ABCC4 XKR9 SLC22A11 XKR4 ABCG1

1.20e-041961127GO:0005319
GeneOntologyMolecularFunctionligand-gated channel activity

BEST3 ITPR1 ITPR2 ZACN P2RX2 CNGB3 KCNK6

1.24e-041971127GO:0022834
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

ITPR1 ITPR2 ZACN P2RX2 CNGB3 KCNK6

1.39e-041401126GO:0099094
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC1 ABCC4 ATP13A2 ABCG1

1.64e-04491124GO:0140359
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

VMP1 XKR9 XKR4 ABCG1

1.91e-04511124GO:0140303
GeneOntologyMolecularFunctionsymporter activity

SLC16A13 SLC15A3 SLC45A4 SLC5A3 SLC12A2 SLC39A14

2.02e-041501126GO:0015293
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

ABCC1 ABCC4 SLC16A13 SLC22A11 SERINC3 SLC39A14 SLC26A11 MFSD10

2.48e-042931128GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC16A13 SLC22A11 SLC15A3 SLC45A4 SLC5A3 SLC12A2 SLC39A14 SLC26A11

2.66e-042961128GO:0015291
GeneOntologyMolecularFunctionphospholipid scramblase activity

VMP1 XKR9 XKR4

2.80e-04231123GO:0017128
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ABCC1 ABCC4 SLC22A11 BEST3 SLC12A2 SLC26A11

4.09e-041711126GO:0015103
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO1H KIF1B KIFC2 MYO3B MYO15A

5.37e-041181125GO:0003774
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC15A3 SLC45A4 SLC5A3 SLC12A2 SLC39A14

5.58e-041191125GO:0015294
GeneOntologyMolecularFunctionglutathione transmembrane transporter activity

ABCC1 ABCC4

6.43e-0471122GO:0034634
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

ABCC4 SLC5A3 ABCG1 MFSD10

6.47e-04701124GO:1901618
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCC1 ABCC4 SLC22A11 ABCG1

7.58e-04731124GO:0170055
GeneOntologyMolecularFunctionphospholipid transporter activity

VMP1 XKR9 XKR4 ABCG1

7.98e-04741124GO:0005548
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

ITPR1 ITPR2 CNGB3

8.29e-04331123GO:0005217
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC1 ABCC4

8.54e-0481122GO:0015431
GeneOntologyMolecularFunctionalcohol transmembrane transporter activity

ABCC4 MFSD10

8.54e-0481122GO:0015665
GeneOntologyMolecularFunctiontripeptide transmembrane transporter activity

ABCC1 ABCC4

1.09e-0391122GO:0042937
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO1H MYO3B MYO15A

1.26e-03381123GO:0000146
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC1 ABCC4

1.36e-03101122GO:0043225
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC15A3 ATP13A2 SLC45A4 SLC5A3 SLC12A2 SLC39A14 SLC26A11

1.55e-033011127GO:0022853
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1A CACNA1E HTR1B KCNS1 KCNK6

1.67e-031521125GO:0022843
GeneOntologyMolecularFunctionamide transmembrane transporter activity

ABCC1 ABCC4 SLC15A3

1.68e-03421123GO:0042887
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1A CACNA1E HTR1B

2.19e-03461123GO:0005245
GeneOntologyMolecularFunctionATP-dependent activity

ABCC1 ABCC4 MYO1H KIF1B HELQ ATP13A2 KIFC2 ABCG1 MYO3B MYO15A

2.39e-0361411210GO:0140657
GeneOntologyMolecularFunctionalcohol binding

GPR155 ITPR1 ITPR2 ABCG1

2.61e-031021124GO:0043178
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

ABCC4 SLC22A11

2.72e-03141122GO:0015132
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1A CACNA1E

2.72e-03141122GO:0008331
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

ITPR1 ITPR2

2.72e-03141122GO:0070679
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC1 ABCC4

3.12e-03151122GO:0008559
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

ABCC4 SLC22A11

3.12e-03151122GO:0071714
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC1 ABCC4 ATP13A2 ABCG1

3.32e-031091124GO:0042626
GeneOntologyMolecularFunctionefflux transmembrane transporter activity

ABCC1 ABCC4

3.55e-03161122GO:0015562
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1A CACNA1E HTR1B KCNS1 KCNK6

3.64e-031821125GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1A CACNA1E HTR1B KCNS1 KCNK6

3.81e-031841125GO:0022832
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC45A4 SLC5A3

4.01e-03171122GO:0005402
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

ITPR1 ITPR2

4.50e-03181122GO:0015278
GeneOntologyMolecularFunctionadenylate cyclase activity

NPR1 ADCY8

4.50e-03181122GO:0004016
GeneOntologyMolecularFunctionmechanosensitive monoatomic ion channel activity

TMC3 TRPV4

4.50e-03181122GO:0008381
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

ABCC1 ABCC4 SLC26A11

4.88e-03611123GO:1901682
GeneOntologyMolecularFunctionnucleotide receptor activity

GPR87 P2RX2

6.69e-03221122GO:0016502
GeneOntologyMolecularFunctionpurinergic nucleotide receptor activity

GPR87 P2RX2

6.69e-03221122GO:0001614
GeneOntologyMolecularFunctionamide binding

CACNA1A NPR1 SRD5A2 P2RX2 GLP1R TM2D1

6.82e-032991126GO:0033218
GeneOntologyMolecularFunctionsterol binding

GPR155 GPR141 ABCG1

7.44e-03711123GO:0032934
GeneOntologyMolecularFunctioncyclase activity

NPR1 ADCY8

7.94e-03241122GO:0009975
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

TRPM6 CACNA1A VMP1 CACNA1E ABCC1 ABCC4 DRD2 BEST3 SLC15A3 GRM6 TMC3 ATP13A2 ITPR1 ITPR2 SLC5A3 CCR2 ZACN SLC12A2 TMEM168 TRPM3 P2RX2 GLP1R CNGB3 KCNS1 TRPV4 KCNK6 SLC39A14 MICU2 SLC26A11

5.68e-13111511029GO:0034220
GeneOntologyBiologicalProcessmonoatomic ion transport

TRPM6 CACNA1A VMP1 CACNA1E ABCC1 ABCC4 DRD2 HTR1B SLC22A11 BEST3 SLC15A3 GRM6 TMC3 ATP13A2 ITPR1 ITPR2 SLC5A3 CCR2 ZACN SLC12A2 TMEM168 TRPM3 P2RX2 GLP1R CNGB3 KCNS1 TRPV4 KCNK6 SLC39A14 MICU2 SLC26A11

3.09e-12137411031GO:0006811
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

TRPM6 CACNA1A VMP1 CACNA1E DRD2 SLC15A3 GRM6 ATP13A2 ITPR1 ITPR2 SLC5A3 ZACN SLC12A2 TMEM168 TRPM3 P2RX2 GLP1R CNGB3 KCNS1 TRPV4 KCNK6 SLC39A14 MICU2

7.52e-1094211023GO:0098655
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

TRPM6 CACNA1A VMP1 CACNA1E DRD2 BEST3 SLC15A3 GRM6 ITPR1 ITPR2 SLC5A3 SLC12A2 TMEM168 TRPM3 P2RX2 GLP1R KCNS1 TRPV4 KCNK6 SLC39A14 MICU2 SLC26A11

1.69e-08101711022GO:0098660
GeneOntologyBiologicalProcessmonoatomic cation transport

TRPM6 CACNA1A VMP1 CACNA1E DRD2 SLC15A3 GRM6 ATP13A2 ITPR1 ITPR2 SLC5A3 ZACN SLC12A2 TMEM168 TRPM3 P2RX2 GLP1R CNGB3 KCNS1 TRPV4 KCNK6 SLC39A14 MICU2

3.61e-08115711023GO:0006812
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

NPR1 TPRA1 DRD2 HTR1B TRHR SIGMAR1 OR2T7 FPR1 GPR141 TAAR3P GPR87 GRM6 ADCY8 GPR179 ITPR1 CCR2 OR2W3 GPR161 OR51B5 OR4P4 OR14A2 GLP1R SLC39A14 TM2D1 DAGLA

6.24e-08139511025GO:0007186
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

TRPM6 CACNA1A VMP1 CACNA1E DRD2 SLC15A3 GRM6 ITPR1 ITPR2 SLC5A3 SLC12A2 TMEM168 TRPM3 P2RX2 GLP1R KCNS1 TRPV4 KCNK6 SLC39A14 MICU2

8.01e-0892211020GO:0098662
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

TRPM6 CACNA1A VMP1 CACNA1E DRD2 GRM6 ITPR1 ITPR2 TRPM3 P2RX2 GLP1R TRPV4 MICU2

1.74e-0739211013GO:0070588
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

CACNA1A DRD2 HTR1B ATP13A2 ADCY8 ITPR1 ITPR2 CCR2 P2RX2 GLP1R TRPV4 MICU2

4.90e-0735911012GO:0006874
GeneOntologyBiologicalProcessinorganic ion homeostasis

CACNA1A NPR1 DRD2 HTR1B ATP13A2 ADCY8 ITPR1 ITPR2 CCR2 SLC12A2 P2RX2 GLP1R TRPV4 SLC39A14 MICU2

1.09e-0662211015GO:0098771
GeneOntologyBiologicalProcesscalcium ion homeostasis

CACNA1A DRD2 HTR1B ATP13A2 ADCY8 ITPR1 ITPR2 CCR2 P2RX2 GLP1R TRPV4 MICU2

1.14e-0638911012GO:0055074
GeneOntologyBiologicalProcessmetal ion transport

TRPM6 CACNA1A VMP1 CACNA1E DRD2 GRM6 ITPR1 ITPR2 SLC5A3 SLC12A2 TMEM168 TRPM3 P2RX2 GLP1R KCNS1 TRPV4 KCNK6 SLC39A14 MICU2

1.31e-06100011019GO:0030001
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

CACNA1A CACNA1E DRD2 GRM6 ITPR1 ITPR2 P2RX2 GLP1R TRPV4

2.48e-062171109GO:0097553
GeneOntologyBiologicalProcessamide transport

CACNA1E ABCC1 ABCC4 DRD2 PTPMT1 SLC15A3 ADCY8 ITPR1 SGPP1 ABCG1 GLP1R TRPV4

2.53e-0642011012GO:0042886
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

CACNA1A TRHR FPR1 ADCY8 ITPR1 CCR2 P2RX2 GLP1R TRPV4

3.21e-062241109GO:0007204
GeneOntologyBiologicalProcesscalcium ion transport

TRPM6 CACNA1A VMP1 CACNA1E DRD2 GRM6 ITPR1 ITPR2 TRPM3 P2RX2 GLP1R TRPV4 MICU2

3.24e-0650911013GO:0006816
GeneOntologyBiologicalProcessintracellular chemical homeostasis

CACNA1A CACNA1E DRD2 HTR1B PTPMT1 ATP13A2 ADCY8 ITPR1 ITPR2 CCR2 ABCG1 SLC12A2 P2RX2 GLP1R TRPV4 SLC39A14 MICU2

3.30e-0686611017GO:0055082
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1A CACNA1E ABCC1 SLC15A3 GRM6 SLC5A3 SLC12A2 TRPV4 SLC39A14

3.99e-062301109GO:0098739
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

CACNA1A DRD2 HTR1B ATP13A2 ADCY8 ITPR1 ITPR2 CCR2 SLC12A2 P2RX2 GLP1R TRPV4 SLC39A14 MICU2

4.64e-0661111014GO:0030003
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

CACNA1A NPR1 DRD2 HTR1B ATP13A2 ADCY8 ITPR1 ITPR2 CCR2 SLC12A2 P2RX2 GLP1R TRPV4 SLC39A14 MICU2

5.06e-0670511015GO:0055080
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

CACNA1A DRD2 HTR1B ATP13A2 ADCY8 ITPR1 ITPR2 CCR2 SLC12A2 P2RX2 GLP1R TRPV4 SLC39A14 MICU2

5.69e-0662211014GO:0006873
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

CACNA1A NPR1 DRD2 HTR1B ATP13A2 ADCY8 ITPR1 ITPR2 CCR2 SLC12A2 P2RX2 GLP1R TRPV4 SLC39A14 MICU2

6.20e-0671711015GO:0050801
GeneOntologyBiologicalProcessimport into cell

CACNA1A CACNA1E ABCC1 DRD2 HTR1B XKR9 MYO1H SLC15A3 XKR4 GRM6 SLC5A3 CCR2 SLC12A2 FCER1G PIP5K1A TRPV4 SLC39A14 MYO15A

1.45e-05107411018GO:0098657
GeneOntologyBiologicalProcesscellular homeostasis

CACNA1A CACNA1E DRD2 HTR1B PTPMT1 ATP13A2 ADCY8 ITPR1 ITPR2 CCR2 ABCG1 SLC12A2 P2RX2 GLP1R TRPV4 SLC39A14 MICU2

1.69e-0598111017GO:0019725
GeneOntologyBiologicalProcesslipid translocation

VMP1 ABCC1 XKR9 XKR4 ABCG1

1.70e-05601105GO:0034204
GeneOntologyBiologicalProcessorganic anion transport

CACNA1A ABCC1 ABCC4 SLC16A13 DRD2 HTR1B SLC22A11 SLC12A2 SERINC3 SLC39A14 SLC26A11 MFSD10

1.98e-0551511012GO:0015711
GeneOntologyBiologicalProcessregulation of secretion

CACNA1A CACNA1E NPR1 DRD2 HTR1B PTPMT1 ATP13A2 ADCY8 ITPR1 CCR2 ABCG1 SLC12A2 FCER1G P2RX2 GLP1R

2.29e-0580111015GO:0051046
GeneOntologyBiologicalProcesssecretion

CACNA1A CACNA1E ABCC4 NPR1 DRD2 HTR1B PTPMT1 ATP13A2 AQP5 ADCY8 STAT5A ITPR1 CCR2 ABCG1 SLC12A2 FCER1G P2RX2 GLP1R TRPV4

2.30e-05122111019GO:0046903
GeneOntologyBiologicalProcessregulation of membrane lipid distribution

VMP1 ABCC1 XKR9 XKR4 ABCG1

2.52e-05651105GO:0097035
GeneOntologyBiologicalProcessneuron-neuron synaptic transmission

CACNA1A DRD2 KIF1B

3.14e-05121103GO:0007270
GeneOntologyBiologicalProcesschemical homeostasis

CACNA1A CACNA1E NPR1 DRD2 HTR1B PTPMT1 TM6SF2 ATP13A2 ADCY8 ITPR1 ITPR2 CCR2 ABCG1 SLC12A2 P2RX2 GLP1R TRPV4 SLC39A14 MICU2

3.14e-05124911019GO:0048878
GeneOntologyBiologicalProcessregulation of secretion by cell

CACNA1A CACNA1E DRD2 HTR1B PTPMT1 ATP13A2 ADCY8 ITPR1 CCR2 ABCG1 SLC12A2 FCER1G P2RX2 GLP1R

3.93e-0574011014GO:1903530
GeneOntologyBiologicalProcesssignal release

CACNA1A CACNA1E ABCC4 DRD2 HTR1B PTPMT1 ADCY8 ITPR1 ABCG1 FCER1G P2RX2 GLP1R TRPV4

4.51e-0565311013GO:0023061
GeneOntologyBiologicalProcesscarboxylic acid transport

CACNA1A ABCC1 ABCC4 SLC16A13 DRD2 HTR1B SLC22A11 SLC12A2 SERINC3 SLC26A11

6.91e-0541011010GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

CACNA1A ABCC1 ABCC4 SLC16A13 DRD2 HTR1B SLC22A11 SLC12A2 SERINC3 SLC26A11

7.19e-0541211010GO:0015849
GeneOntologyBiologicalProcessregulation of cytosolic calcium ion concentration

CACNA1A HTR1B ADCY8 ITPR1 P2RX2

8.69e-05841105GO:0051480
GeneOntologyBiologicalProcessoligopeptide transmembrane transport

ABCC1 ABCC4 SLC15A3

9.50e-05171103GO:0035672
GeneOntologyBiologicalProcessregulation of protein secretion

CACNA1E DRD2 PTPMT1 ATP13A2 ADCY8 ITPR1 ABCG1 SLC12A2 GLP1R

1.09e-043501109GO:0050708
GeneOntologyBiologicalProcessnegative regulation of adenylate cyclase activity

DRD2 GPR87 CCR2

1.14e-04181103GO:0007194
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1A CACNA1E GRM6 SLC12A2 TRPV4 SLC39A14

1.14e-041421106GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1A CACNA1E GRM6 SLC12A2 TRPV4 SLC39A14

1.14e-041421106GO:0098659
GeneOntologyBiologicalProcesspeptide transport

CACNA1E DRD2 PTPMT1 SLC15A3 ADCY8 ITPR1 ABCG1 GLP1R TRPV4

1.21e-043551109GO:0015833
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1A CACNA1E GRM6 TRPV4

1.24e-04481104GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1A CACNA1E GRM6 TRPV4

1.24e-04481104GO:1902656
GeneOntologyBiologicalProcessexport from cell

CACNA1A CACNA1E ABCC1 ABCC4 DRD2 HTR1B PTPMT1 ATP13A2 ADCY8 ITPR1 CCR2 ABCG1 SLC12A2 FCER1G P2RX2 GLP1R TRPV4

1.26e-04115311017GO:0140352
GeneOntologyBiologicalProcessnegative regulation of cyclase activity

DRD2 GPR87 CCR2

1.34e-04191103GO:0031280
GeneOntologyBiologicalProcesssecretion by cell

CACNA1A CACNA1E ABCC4 DRD2 HTR1B PTPMT1 ATP13A2 ADCY8 ITPR1 CCR2 ABCG1 SLC12A2 FCER1G P2RX2 GLP1R TRPV4

1.63e-04106411016GO:0032940
GeneOntologyBiologicalProcessnegative regulation of mast cell apoptotic process

STAT5A FCER1G

1.68e-0441102GO:0033026
GeneOntologyBiologicalProcesspositive regulation of renal sodium excretion

NPR1 DRD2

1.68e-0441102GO:0035815
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

ABCC1 ABCC4 BEST3 SLC12A2 SLC39A14 SLC26A11

1.71e-041531106GO:0098656
GeneOntologyBiologicalProcesssensory perception

CACNA1E DRD2 OR2T7 TAAR3P GRM6 GPR179 CCR2 OR2W3 OR51B5 OR4P4 OR14A2 SLC12A2 P2RX2 MYO3B CNGB3 MYO15A

1.77e-04107211016GO:0007600
GeneOntologyBiologicalProcessnegative regulation of lyase activity

DRD2 GPR87 CCR2

2.11e-04221103GO:0051350
GeneOntologyBiologicalProcessphospholipid translocation

VMP1 ABCC1 XKR9 XKR4

2.12e-04551104GO:0045332
GeneOntologyBiologicalProcesslipid localization

VMP1 ABCC1 ABCC4 DRD2 XKR9 SIGMAR1 SLC22A11 XKR4 STAT5A SGPP1 ABCG1

2.18e-0456511011GO:0010876
GeneOntologyBiologicalProcessorganophosphate ester transport

VMP1 ABCC1 ABCC4 XKR9 XKR4 ABCG1

2.34e-041621106GO:0015748
GeneOntologyBiologicalProcessregulation of insulin secretion

CACNA1E DRD2 PTPMT1 ADCY8 ITPR1 ABCG1 GLP1R

2.42e-042311107GO:0050796
GeneOntologyBiologicalProcessoligopeptide transport

ABCC1 ABCC4 SLC15A3

2.42e-04231103GO:0006857
GeneOntologyBiologicalProcessregulation of exocytosis

CACNA1A CACNA1E HTR1B ATP13A2 CCR2 FCER1G P2RX2

2.55e-042331107GO:0017157
GeneOntologyBiologicalProcessregulation of regulated secretory pathway

CACNA1A CACNA1E HTR1B CCR2 FCER1G P2RX2

2.58e-041651106GO:1903305
GeneOntologyBiologicalProcessphospholipid transport

VMP1 ABCC1 XKR9 XKR4 ABCG1

2.60e-041061105GO:0015914
GeneOntologyBiologicalProcessregulation of monoatomic ion transport

VMP1 DRD2 HTR1B BEST3 GRM6 ITPR1 CCR2 TMEM168 P2RX2 GLP1R KCNS1

2.61e-0457711011GO:0043269
GeneOntologyBiologicalProcessregulation of adenylate cyclase activity

DRD2 GPR87 CCR2 GLP1R

2.78e-04591104GO:0045761
GeneOntologyBiologicalProcessplasma membrane phospholipid scrambling

VMP1 XKR9 XKR4

3.51e-04261103GO:0017121
GeneOntologyBiologicalProcessregulation of presynaptic cytosolic calcium ion concentration

CACNA1A HTR1B P2RX2

3.51e-04261103GO:0099509
GeneOntologyBiologicalProcesslipid transport

VMP1 ABCC1 ABCC4 DRD2 XKR9 SIGMAR1 SLC22A11 XKR4 SGPP1 ABCG1

3.78e-0450611010GO:0006869
GeneOntologyBiologicalProcessregulation of mast cell apoptotic process

STAT5A FCER1G

4.17e-0461102GO:0033025
GeneOntologyBiologicalProcessmast cell apoptotic process

STAT5A FCER1G

4.17e-0461102GO:0033024
GeneOntologyBiologicalProcesspeptide hormone secretion

CACNA1E DRD2 PTPMT1 ADCY8 ITPR1 ABCG1 GLP1R TRPV4

4.25e-043341108GO:0030072
GeneOntologyBiologicalProcessmonoatomic anion transport

ABCC1 ABCC4 BEST3 SLC12A2 SLC39A14 SLC26A11

4.49e-041831106GO:0006820
GeneOntologyBiologicalProcessregulation of cyclase activity

DRD2 GPR87 CCR2 GLP1R

5.07e-04691104GO:0031279
GeneOntologyBiologicalProcesspeptide secretion

CACNA1E DRD2 PTPMT1 ADCY8 ITPR1 ABCG1 GLP1R TRPV4

5.07e-043431108GO:0002790
GeneOntologyBiologicalProcesspositive regulation of secretion

NPR1 DRD2 ATP13A2 ADCY8 ITPR1 ABCG1 SLC12A2 FCER1G GLP1R

5.39e-044351109GO:0051047
GeneOntologyBiologicalProcesscirculatory system process

CACNA1E ABCC1 ABCC4 NPR1 DRD2 HTR1B SLC5A3 SLC12A2 P2RX2 GLP1R TRPV4 KCNK6

5.40e-0473311012GO:0003013
GeneOntologyBiologicalProcessleukotriene transport

ABCC1 ABCC4

5.82e-0471102GO:0071716
GeneOntologyBiologicalProcessmast cell homeostasis

STAT5A FCER1G

5.82e-0471102GO:0033023
GeneOntologyBiologicalProcessinterleukin-3-mediated signaling pathway

STAT5A FCER1G

5.82e-0471102GO:0038156
GeneOntologyBiologicalProcessregulation of lyase activity

DRD2 GPR87 CCR2 GLP1R

6.28e-04731104GO:0051339
GeneOntologyBiologicalProcessicosanoid transport

ABCC1 ABCC4 DRD2 SLC22A11

6.28e-04731104GO:0071715
GeneOntologyBiologicalProcessbehavioral response to pain

CACNA1A CACNA1E P2RX2

6.54e-04321103GO:0048266
GeneOntologyBiologicalProcessinsulin secretion

CACNA1E DRD2 PTPMT1 ADCY8 ITPR1 ABCG1 GLP1R

6.72e-042741107GO:0030073
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

CACNA1A DRD2 HTR1B GRM6 CCR2

7.12e-041321105GO:0035249
GeneOntologyBiologicalProcessregulation of peptide hormone secretion

CACNA1E DRD2 PTPMT1 ADCY8 ITPR1 ABCG1 GLP1R

7.16e-042771107GO:0090276
GeneOntologyBiologicalProcessglutathione transmembrane transport

ABCC1 ABCC4

7.73e-0481102GO:0034775
GeneOntologyBiologicalProcessplatelet degranulation

ABCC4 FCER1G

7.73e-0481102GO:0002576
GeneOntologyBiologicalProcessregulation of renal sodium excretion

NPR1 DRD2

7.73e-0481102GO:0035813
GeneOntologyBiologicalProcessregulation of peptide transport

CACNA1E DRD2 PTPMT1 ADCY8 ITPR1 ABCG1 GLP1R

7.95e-042821107GO:0090087
GeneOntologyBiologicalProcessregulation of peptide secretion

CACNA1E DRD2 PTPMT1 ADCY8 ITPR1 ABCG1 GLP1R

7.95e-042821107GO:0002791
GeneOntologyBiologicalProcesslocomotory behavior

CACNA1A CACNA1E DRD2 GRM6 ADCY8 MYO15A SEZ6L

8.29e-042841107GO:0007626
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

DRD2 HTR1B FPR1 GRM6 ADCY8 GPR161 GLP1R

8.64e-042861107GO:0007188
GeneOntologyBiologicalProcessneuromuscular synaptic transmission

CACNA1A KIF1B P2RX2

9.27e-04361103GO:0007274
GeneOntologyBiologicalProcessregulated exocytosis

CACNA1A CACNA1E ABCC4 HTR1B CCR2 FCER1G P2RX2

9.55e-042911107GO:0045055
GeneOntologyBiologicalProcessregulation of neurotransmitter transport

CACNA1A CACNA1E DRD2 HTR1B P2RX2

9.58e-041411105GO:0051588
GeneOntologyBiologicalProcessinterleukin-2 production

CD83 STAT5A CCR2 FCER1G

9.73e-04821104GO:0032623
GeneOntologyBiologicalProcessprotein complex oligomerization

TRPM6 SIGMAR1 AQP5 ADCY8 ITPR1 TRPM3 KCNS1

1.05e-032961107GO:0051259
GeneOntologyBiologicalProcessregulation of hormone levels

CACNA1A CACNA1E DRD2 PTPMT1 SRD5A2 ADCY8 ITPR1 ABCG1 GLP1R TRPV4 SLC39A14

1.07e-0368411011GO:0010817
GeneOntologyBiologicalProcessprotein secretion

CACNA1E DRD2 PTPMT1 ATP13A2 ADCY8 ITPR1 ABCG1 SLC12A2 GLP1R

1.08e-034801109GO:0009306
GeneOntologyBiologicalProcesstransepithelial transport

ABCC1 ITPR1 SLC12A2

1.09e-03381103GO:0070633
GeneOntologyBiologicalProcessestablishment of protein localization to extracellular region

CACNA1E DRD2 PTPMT1 ATP13A2 ADCY8 ITPR1 ABCG1 SLC12A2 GLP1R

1.13e-034831109GO:0035592
GeneOntologyBiologicalProcessresponse to nitrogen compound

CACNA1A ABCC1 DRD2 HTR1B SRD5A2 INSRR ADCY8 STAT5A ITPR1 ITPR2 UBE4A FCER1G P2RX2 GLP1R TRPV4 SLC39A14

1.15e-03127211016GO:1901698
GeneOntologyBiologicalProcessresponse to carbohydrate

CACNA1E PTPMT1 ADCY8 ABCG1 P2RX2 GLP1R SLC39A14

1.16e-033011107GO:0009743
GeneOntologyCellularComponentapical plasma membrane

TRPM6 ABCC1 ABCC4 SLC22A11 SI AQP5 ADCY8 SLC5A3 SLC12A2 P2RX2 TRPV4 SLC39A14 SLC26A11

2.12e-0648711213GO:0016324
GeneOntologyCellularComponentapical part of cell

TRPM6 ABCC1 ABCC4 SLC22A11 SI AQP5 ADCY8 SLC5A3 SLC12A2 P2RX2 TRPV4 SLC39A14 SLC26A11

1.73e-0559211213GO:0045177
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ABCC4 DRD2 FPR1 KIF1B SLC35F1 SLC15A3 ATP13A2 AQP5 ADCY8 ITPR1 ITPR2 ARFGEF3 GPR161 SLC12A2 FCER1G SBF2 SLC39A14 DAGLA MFSD10

6.26e-05130711219GO:0030659
GeneOntologyCellularComponentsynaptic membrane

CACNA1A CACNA1E DRD2 HTR1B SIGMAR1 GRM6 ADCY8 GPR179 ITPR1 P2RX2 DAGLA SEZ6L

6.91e-0558311212GO:0097060
GeneOntologyCellularComponentvesicle membrane

ABCC4 DRD2 FPR1 KIF1B SLC35F1 SLC15A3 ATP13A2 AQP5 ADCY8 ITPR1 ITPR2 ARFGEF3 GPR161 SLC12A2 FCER1G SBF2 SLC39A14 DAGLA MFSD10

7.51e-05132511219GO:0012506
GeneOntologyCellularComponentsomatodendritic compartment

CACNA1A CACNA1E DRD2 HTR1B KIF1B SRD5A2 GRM6 ATP13A2 ADCY8 GPR179 ITPR1 CCR2 BMPR1A SLC12A2 P2RX2 KLHL14 DAGLA SEZ6L

9.01e-05122811218GO:0036477
GeneOntologyCellularComponentbasal plasma membrane

ABCC1 ABCC4 SLC22A11 AQP5 ADCY8 SLC5A3 SLC12A2 SLC39A14 SLC26A11

1.23e-043541129GO:0009925
GeneOntologyCellularComponentbasal part of cell

ABCC1 ABCC4 SLC22A11 AQP5 ADCY8 SLC5A3 SLC12A2 SLC39A14 SLC26A11

2.01e-043781129GO:0045178
GeneOntologyCellularComponentcation channel complex

CACNA1A CACNA1E SLC5A3 CNGB3 KCNS1 KCNK6 MICU2

2.76e-042351127GO:0034703
GeneOntologyCellularComponentplatelet dense granule membrane

ABCC4 ITPR1

4.21e-0461122GO:0031088
GeneOntologyCellularComponentcell projection membrane

TRPM6 DRD2 TMEM17 GPR161 SLC12A2 PIP5K1A TRPV4 DAGLA MFSD10

5.23e-044311129GO:0031253
GeneOntologyCellularComponentneuronal cell body

CACNA1A CACNA1E DRD2 SRD5A2 ATP13A2 ADCY8 ITPR1 CCR2 BMPR1A SLC12A2 P2RX2 KLHL14 SEZ6L

5.31e-0483511213GO:0043025
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1A CACNA1E BEST3 SLC5A3 CNGB3 KCNS1 KCNK6 MICU2

9.85e-043781128GO:0034702
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ITPR2

9.99e-0491122GO:0031095
GeneOntologyCellularComponentcell body

CACNA1A CACNA1E DRD2 SRD5A2 ATP13A2 ADCY8 ITPR1 CCR2 BMPR1A SLC12A2 P2RX2 KLHL14 SEZ6L

1.41e-0392911213GO:0044297
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ITPR2

1.52e-03111122GO:0031094
GeneOntologyCellularComponentpostsynaptic membrane

CACNA1A CACNA1E DRD2 SIGMAR1 GRM6 GPR179 DAGLA SEZ6L

1.53e-034051128GO:0045211
GeneOntologyCellularComponentbasolateral plasma membrane

ABCC1 ABCC4 ADCY8 SLC5A3 SLC12A2 SLC39A14 SLC26A11

1.70e-033201127GO:0016323
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1A CACNA1E BEST3 SLC5A3 ZACN CNGB3 KCNS1 KCNK6 MICU2

2.02e-035231129GO:1902495
GeneOntologyCellularComponentdendrite

CACNA1A DRD2 HTR1B KIF1B GRM6 ADCY8 GPR179 ITPR1 CCR2 BMPR1A P2RX2 DAGLA

2.17e-0385811212GO:0030425
GeneOntologyCellularComponentdendritic tree

CACNA1A DRD2 HTR1B KIF1B GRM6 ADCY8 GPR179 ITPR1 CCR2 BMPR1A P2RX2 DAGLA

2.21e-0386011212GO:0097447
GeneOntologyCellularComponenttransporter complex

CACNA1A CACNA1E BEST3 SLC5A3 ZACN CNGB3 KCNS1 KCNK6 MICU2

2.83e-035501129GO:1990351
GeneOntologyCellularComponentcell tip

GRM6 GPR179

3.67e-03171122GO:0051286
GeneOntologyCellularComponentendoplasmic reticulum membrane

VMP1 SIGMAR1 SRD5A2 TM6SF2 GRM6 ZDHHC4 ITPR1 ITPR2 SGPP1 PIGQ NBAS ABCG1 TMEM39A KLHL14 SEZ6L

3.77e-03129311215GO:0005789
GeneOntologyCellularComponentpresynaptic membrane

CACNA1A CACNA1E DRD2 HTR1B ADCY8 P2RX2

3.80e-032771126GO:0042734
GeneOntologyCellularComponentnuclear inner membrane

SIGMAR1 ITPR1 MFSD10

3.91e-03591123GO:0005637
GeneOntologyCellularComponentmyosin complex

MYO1H MYO3B MYO15A

3.91e-03591123GO:0016459
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

VMP1 SIGMAR1 SRD5A2 TM6SF2 GRM6 ZDHHC4 ITPR1 ITPR2 SGPP1 PIGQ NBAS ABCG1 TMEM39A KLHL14 SEZ6L

3.93e-03129911215GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

VMP1 SIGMAR1 SRD5A2 TM6SF2 GRM6 ZDHHC4 ITPR1 ITPR2 SGPP1 PIGQ NBAS ABCG1 TMEM39A KLHL14 SEZ6L

4.79e-03132711215GO:0042175
GeneOntologyCellularComponentcell pole

GRM6 GPR179

5.08e-03201122GO:0060187
GeneOntologyCellularComponentplatelet dense granule

ABCC4 ITPR1

5.59e-03211122GO:0042827
GeneOntologyCellularComponentvacuolar membrane

GPR155 VMP1 FPR1 SLC15A3 ATP13A2 SBF2 SLC39A14 SLC26A11

5.97e-035071128GO:0005774
HumanPhenoCraniofacial dystonia

CACNA1A DRD2 SIGMAR1 ATP13A2 TRPM3 TRPV4 SLC39A14

3.26e-05123397HP:0012179
HumanPhenoTorticollis

CACNA1A DRD2 SIGMAR1 ATP13A2 TRPM3 TRPV4

4.33e-0587396HP:0000473
DomainIon_trans_dom

TRPM6 CACNA1A CACNA1E ITPR1 ITPR2 TRPM3 CNGB3 KCNS1 TRPV4

1.86e-081141079IPR005821
DomainIon_trans

TRPM6 CACNA1A CACNA1E ITPR1 ITPR2 TRPM3 CNGB3 KCNS1 TRPV4

1.86e-081141079PF00520
DomainInsP3_rcpt-bd

ITPR1 ITPR2

9.72e-0531072IPR000493
DomainTRPM_tetra

TRPM6 TRPM3

1.94e-0441072IPR032415
DomainTRPM_tetra

TRPM6 TRPM3

1.94e-0441072PF16519
DomainRIH_assoc

ITPR1 ITPR2

4.80e-0461072PF08454
DomainRIH_assoc-dom

ITPR1 ITPR2

4.80e-0461072IPR013662
DomainRIH_dom

ITPR1 ITPR2

4.80e-0461072IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2

4.80e-0461072IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2

4.80e-0461072IPR015925
Domain-

ITPR1 ITPR2

4.80e-04610721.25.10.30
DomainRYDR_ITPR

ITPR1 ITPR2

4.80e-0461072PF01365
DomainIns145_P3_rec

ITPR1 ITPR2

4.80e-0461072PF08709
Domain7tm_1

DRD2 HTR1B TRHR FPR1 GPR141 TAAR3P GPR87 CCR2 OR2W3 GPR161 OR51B5 OR4P4

4.98e-0467710712PF00001
DomainG_PROTEIN_RECEP_F1_1

DRD2 HTR1B TRHR FPR1 GPR141 TAAR3P GPR87 CCR2 OR2W3 GPR161 OR51B5 OR4P4

5.52e-0468510712PS00237
DomainG_PROTEIN_RECEP_F1_2

DRD2 HTR1B TRHR FPR1 GPR141 TAAR3P GPR87 CCR2 OR2W3 GPR161 OR51B5 OR4P4

5.97e-0469110712PS50262
DomainGPCR_Rhodpsn

DRD2 HTR1B TRHR FPR1 GPR141 TAAR3P GPR87 CCR2 OR2W3 GPR161 OR51B5 OR4P4

6.04e-0469210712IPR000276
DomainVDCC_a1su_IQ

CACNA1A CACNA1E

6.70e-0471072IPR014873
DomainGPHH

CACNA1A CACNA1E

6.70e-0471072PF16905
DomainGPHH_dom

CACNA1A CACNA1E

6.70e-0471072IPR031649
DomainCa_chan_IQ

CACNA1A CACNA1E

6.70e-0471072SM01062
DomainCa_chan_IQ

CACNA1A CACNA1E

6.70e-0471072PF08763
DomainMFS_dom

SLC16A13 SLC22A11 SLC15A3 SLC45A4 MFSD10

1.04e-031341075IPR020846
DomainMIR

ITPR1 ITPR2

1.42e-03101072PS50919
DomainMIR

ITPR1 ITPR2

1.42e-03101072PF02815
DomainMIR

ITPR1 ITPR2

1.42e-03101072SM00472
DomainMIR_motif

ITPR1 ITPR2

1.42e-03101072IPR016093
DomainVDCCAlpha1

CACNA1A CACNA1E

1.42e-03101072IPR002077
DomainGPCR_Rhodpsn_7TM

DRD2 HTR1B TRHR FPR1 GPR141 GPR87 CCR2 OR2W3 GPR161 OR51B5 OR4P4

1.59e-0367010711IPR017452
DomainXK_rel

XKR9 XKR4

1.73e-03111072IPR018629
DomainXK-related

XKR9 XKR4

1.73e-03111072PF09815
DomainABC_transporter_CS

ABCC1 ABCC4 ABCG1

1.78e-03421073IPR017871
DomainABC_tran

ABCC1 ABCC4 ABCG1

2.62e-03481073PF00005
DomainABC_TRANSPORTER_2

ABCC1 ABCC4 ABCG1

2.62e-03481073PS50893
DomainABC_TRANSPORTER_1

ABCC1 ABCC4 ABCG1

2.78e-03491073PS00211
DomainABC_transporter-like

ABCC1 ABCC4 ABCG1

2.95e-03501073IPR003439
Domain7TM_GPCR_Srsx

DRD2 HTR1B TRHR CCR2

3.94e-031121074SM01381
DomainA/G_cyclase_CS

NPR1 ADCY8

4.18e-03171072IPR018297
DomainChannel_four-helix_dom

CACNA1A CACNA1E KCNS1

4.27e-03571073IPR027359
Domain-

CACNA1A CACNA1E KCNS1

4.27e-035710731.20.120.350
DomainNucleotide_cyclase

NPR1 ADCY8

4.69e-03181072IPR029787
Domain-

NPR1 ADCY8

4.69e-031810723.30.70.1230
DomainGUANYLATE_CYCLASE_1

NPR1 ADCY8

5.22e-03191072PS00452
DomainGuanylate_cyc

NPR1 ADCY8

5.22e-03191072PF00211
DomainGUANYLATE_CYCLASE_2

NPR1 ADCY8

5.22e-03191072PS50125
DomainA/G_cyclase

NPR1 ADCY8

5.22e-03191072IPR001054
DomainCYCc

NPR1 ADCY8

5.22e-03191072SM00044
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

TRPM6 ABCC1 ABCC4 SLC22A11 BEST3 SLC15A3 ATP13A2 AQP5 ADCY8 SLC5A3 ABCG1 SLC12A2 TRPM3 TRPV4 SLC39A14 MICU2 SLC26A11

7.32e-077368117M27287
PathwayWP_GPCRS_ORPHAN

GPR155 TPRA1 GPR179 GPR161

3.67e-0619814MM15991
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

CACNA1A CACNA1E ADCY8 ITPR1 ITPR2 GLP1R

5.51e-0678816M1921
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

TRPM6 ABCC1 ABCC4 BEST3 SLC15A3 ATP13A2 AQP5 SLC5A3 ABCG1 SLC12A2 TRPM3 TRPV4 SLC39A14 MICU2 SLC26A11

6.50e-066818115MM14985
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

CACNA1A CACNA1E ITPR1 ITPR2 GLP1R

2.56e-0561815MM15071
PathwayWP_GPCRS_ODORANT

GPR155 TPRA1 GPR141 TAAR3P GPR87 GPR179 GPR161

3.24e-05157817MM15872
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

CACNA1A CACNA1E ADCY8 ITPR1 ITPR2 GLP1R

3.58e-05108816M17034
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

SIGMAR1 ITPR1 ITPR2

5.01e-0513813M47751
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 P2RX2

5.01e-0513813MM14553
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

CACNA1A CACNA1E ITPR1 ITPR2 GLP1R

5.72e-0572815MM14631
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1A CACNA1E TRHR ADCY8 ITPR1 ITPR2 P2RX2

7.20e-05178817M2890
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ADCY8 ITPR1 ITPR2 GLP1R

9.59e-0542814M791
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 P2RX2

9.70e-0516813M26945
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR1 ITPR2

3.22e-045812M49000
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2 DAGLA

3.84e-0425813MM14511
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2

4.82e-046812M47960
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 P2RX2

4.84e-0427813MM15053
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2 DAGLA

4.84e-0427813M12123
PathwayREACTOME_TRP_CHANNELS

TRPM6 TRPM3 TRPV4

5.40e-0428813MM14943
PathwayREACTOME_TRP_CHANNELS

TRPM6 TRPM3 TRPV4

5.40e-0428813M27241
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 P2RX2

5.40e-0428813M924
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

DRD2 HTR1B TRHR FPR1 GPR87 CCR2 GPR161

7.28e-04260817M39397
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2 GLP1R

8.04e-0432813MM14983
PathwayWP_GPCRS_NONODORANT

DRD2 HTR1B TRHR FPR1 GRM6 CCR2 GLP1R

8.33e-04266817MM15843
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

DRD2 HTR1B TRHR FPR1 GRM6 P2RX2 GLP1R

9.49e-04272817M13380
PathwayREACTOME_SIGNALING_BY_GPCR

DRD2 HTR1B TRHR FPR1 TAAR3P GRM6 ADCY8 ITPR1 ITPR2 GLP1R DAGLA

1.12e-036468111MM14962
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2

1.14e-039812M47852
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2

1.42e-0310812M47661
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1A CACNA1E ADCY8 ITPR1 ITPR2

1.56e-03147815MM15854
PathwayREACTOME_DAG_AND_IP3_SIGNALING

ADCY8 ITPR1 ITPR2

1.66e-0341813M512
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1E

1.73e-0311812MM14498
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1E

1.73e-0311812M26913
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2

1.73e-0311812M49033
PathwayREACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION

ITPR1 ITPR2

1.73e-0311812M27466
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1A CACNA1E

1.73e-0311812M47958
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1A CACNA1E ADCY8 ITPR1 ITPR2

1.76e-03151815M39329
PathwayKEGG_GAP_JUNCTION

DRD2 ADCY8 ITPR1 ITPR2

1.78e-0390814M4013
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

DRD2 HTR1B TAAR3P

1.79e-0342813MM14971
PathwayWP_THYROID_HORMONES_PRODUCTION_AND_PERIPHERAL_DOWNSTREAM_SIGNALING_EFFECTS

NPR1 ADCY8 ITPR2 KLB

2.00e-0393814M39791
PathwayKEGG_ABC_TRANSPORTERS

ABCC1 ABCC4 ABCG1

2.04e-0344813M11911
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

HTR1B FPR1 GRM6 ADCY8 ITPR1 ITPR2 CCR2

2.16e-03314817M600
PathwayREACTOME_SIGNALING_BY_GPCR

DRD2 HTR1B TRHR FPR1 GRM6 ADCY8 ITPR1 ITPR2 CCR2 GLP1R DAGLA

2.18e-037028111M746
PathwayWP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING

ITPR1 DAGLA

2.44e-0313812M39589
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2

2.44e-0313812M47656
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2

2.44e-0313812M47696
PathwayREACTOME_STIMULI_SENSING_CHANNELS

TRPM6 BEST3 TRPM3 TRPV4

2.52e-0399814MM14910
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

SCFD2 DCAKD VMP1 ABCC1 ITPR1 ITPR2 UBE4A NBAS SLC12A2 MFSD10

2.95e-064681121031056421
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

GPR155 TPRA1 GPR141 GRM6 GPR161

5.90e-0679112512679517
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1A CACNA1E ITPR1 ITPR2

6.91e-0638112430786075
Pubmed

ON pathway mutations increase susceptibility to form-deprivation myopia.

GRM6 ITPR1

1.03e-052112226072023
Pubmed

Clinicopathological impact of ABCC1/MRP1 and ABCC4/MRP4 in epithelial ovarian carcinoma.

ABCC1 ABCC4

1.03e-052112224024181
Pubmed

CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion.

CCR2 GLP1R

1.03e-052112223449669
Pubmed

Shear stress regulates aquaporin-5 and airway epithelial barrier function.

AQP5 TRPV4

1.03e-052112218305162
Pubmed

Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.

ITPR1 ITPR2

1.03e-052112215201137
Pubmed

Physiological Cooperation between Aquaporin 5 and TRPV4.

AQP5 TRPV4

1.03e-052112236232935
Pubmed

Microbiota-Produced N-Formyl Peptide fMLF Promotes Obesity-Induced Glucose Intolerance.

FPR1 GLP1R

1.03e-052112231010956
Pubmed

Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.

ITPR1 ITPR2

1.03e-052112223582047
Pubmed

Ultrastructural localization of GPR179 and the impact of mutant forms on retinal function in CSNB1 patients and a mouse model.

GRM6 GPR179

1.03e-052112224084093
Pubmed

Transient receptor potential vanilloid 4 regulates aquaporin-5 abundance under hypotonic conditions.

AQP5 TRPV4

1.03e-052112216537379
Pubmed

Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.

ITPR1 ITPR2

1.03e-052112219120126
Pubmed

Roles of ABCC1 and ABCC4 in Proliferation and Migration of Breast Cancer Cell Lines.

ABCC1 ABCC4

1.03e-052112233081264
Pubmed

Localization of Na(+)-K(+)-ATPase α/β, Na(+)-K(+)-2Cl-cotransporter 1 and aquaporin-5 in human eccrine sweat glands.

AQP5 SLC12A2

1.03e-052112225218052
Pubmed

Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells.

ADCY8 GLP1R

1.03e-052112221046358
Pubmed

Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.

CACNA1A CACNA1E

1.03e-052112216381801
Pubmed

A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery.

AQP5 TRPV4

1.03e-052112216571723
Pubmed

An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.

ITPR1 ITPR2

1.03e-052112218708078
Pubmed

Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers.

DRD2 SIGMAR1

1.03e-052112223637801
Pubmed

Distribution of thyrotropin-releasing hormone (TRH) receptors in the brain of the ataxic mutant mouse, rolling mouse Nagoya.

CACNA1A TRHR

1.03e-05211229013814
Pubmed

TRP channels activated by extracellular hypo-osmoticity in epithelia.

TRPM3 TRPV4

1.03e-052112217233610
Pubmed

Localization of multidrug resistance-associated proteins along the blood-testis barrier in rat, macaque, and human testis.

ABCC1 ABCC4

1.03e-052112224130369
Pubmed

Genetics of alcoholism: a review of recent studies in human and animal models.

DRD2 HTR1B

1.03e-052112210598210
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR2

3.08e-053112210874040
Pubmed

Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).

ABCC1 ABCC4

3.08e-053112216156793
Pubmed

Meloxicam increases intracellular accumulation of doxorubicin via downregulation of multidrug resistance-associated protein 1 (MRP1) in A549 cells.

ABCC1 ABCC4

3.08e-053112226600514
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR2

3.08e-053112220395455
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2

3.08e-053112217437169
Pubmed

Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens.

DRD2 HTR1B

3.08e-053112235545050
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2

3.08e-053112218547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR2

3.08e-053112236350267
Pubmed

Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.

ITPR1 ITPR2

3.08e-053112232320395
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR2

3.08e-053112211413485
Pubmed

The 5'-flanking region of the mouse adenylyl cyclase type VIII gene imparts tissue-specific expression in transgenic mice.

TRHR ADCY8

3.08e-053112210066258
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2

3.08e-053112226009177
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR2

3.08e-05311221693919
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR1 ITPR2

3.08e-053112223955339
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2

3.08e-053112231979185
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1A CACNA1E

3.08e-053112238996073
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR2

3.08e-053112224904548
Pubmed

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.

ABCC1 ABCC4

3.08e-053112215886284
Pubmed

Cocaine-induced endocannabinoid signaling mediated by sigma-1 receptors and extracellular vesicle secretion.

SIGMAR1 DAGLA

3.08e-053112231596232
Pubmed

Tetramerization of STAT5 regulates monocyte differentiation and the dextran sulfate sodium-induced colitis in mice.

STAT5A CCR2

3.08e-053112237153611
Pubmed

Inhibition of endothelial cell Ca²⁺ entry and transient receptor potential channels by Sigma-1 receptor ligands.

SIGMAR1 TRPM3

3.08e-053112223121507
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR1 ITPR2

3.08e-05311229858485
Pubmed

TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema.

AQP5 TRPV4

3.08e-053112232931478
Pubmed

Possible involvement of type 1 inositol 1,4,5-trisphosphate receptors up-regulated by dopamine D1 and D2 receptors in mouse nucleus accumbens neurons in the development of methamphetamine-induced place preference.

DRD2 ITPR1

3.08e-053112223000618
Pubmed

Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier.

ABCC1 ABCC4

3.08e-053112225986174
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR2

3.08e-05311229808793
Pubmed

Age and gender-dependent alternative splicing of P/Q-type calcium channel EF-hand.

CACNA1A MICU2

3.08e-053112217291689
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR2

3.08e-053112218194433
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR1 ITPR2

3.08e-053112227777977
Pubmed

Opioidergic and dopaminergic gene expression in the caudate-putamen and accumbens of the mutant mouse, tottering (tg/tg).

CACNA1A DRD2

3.08e-05311229191109
Pubmed

Mammary epithelial cells are not able to undergo pregnancy-dependent differentiation in the absence of the helix-loop-helix inhibitor Id2.

STAT5A SLC12A2

3.08e-053112212456807
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR1 ITPR2

3.08e-053112217581770
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR1 ITPR2

3.08e-053112218241669
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR1 ITPR2

3.08e-053112219068129
Pubmed

Calcium-binding protein 1 is an inhibitor of agonist-evoked, inositol 1,4,5-trisphosphate-mediated calcium signaling.

CACNA1A ITPR1

3.08e-053112214570872
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2

3.08e-053112217327232
Pubmed

Cross-desensitization of CCR1, but not CCR2, following activation of the formyl peptide receptor FPR1.

FPR1 CCR2

3.08e-053112224778447
Pubmed

Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.

ITPR1 ITPR2

3.08e-053112223223241
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR1 ITPR2

3.08e-053112216014380
Pubmed

Regulation of type 1 IP₃ receptor expression by dopamine D2-like receptors via AP-1 and NFATc4 activation.

DRD2 ITPR1

3.08e-053112223597509
Pubmed

ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.

ABCC1 ABCC4

3.08e-053112221799180
Pubmed

Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.

CACNA1A CACNA1E

3.08e-053112224523520
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR1 ITPR2

3.08e-053112217890015
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR1 ITPR2

3.08e-053112223983250
Pubmed

Regulation of type 1 inositol 1,4,5-triphosphate receptor by dopamine receptors in cocaine-induced place conditioning.

DRD2 ITPR1

3.08e-053112222033896
Pubmed

Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.

ITPR1 ITPR2

3.08e-053112220427533
Pubmed

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.

ITPR1 ITPR2

6.14e-054112225215520
Pubmed

The molecular mechanism of synaptic activity-induced astrocytic volume transient.

ITPR2 SLC12A2

6.14e-054112232706443
Pubmed

miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function.

TRPM3 GLP1R

6.14e-054112229101219
Pubmed

Association study between clinical response to rizatriptan and some candidate genes.

DRD2 HTR1B

6.14e-054112217563839
Pubmed

Loss of inhibition by brain natriuretic peptide over P2X3 receptors contributes to enhanced spike firing of trigeminal ganglion neurons in a mouse model of familial hemiplegic migraine type-1.

CACNA1A NPR1

6.14e-054112227346147
Pubmed

2-Arachidonoylglycerol mobilization following brief synaptic stimulation in the dorsal lateral striatum requires glutamatergic and cholinergic neurotransmission.

DRD2 DAGLA

6.14e-054112234896118
Pubmed

Cerebellar granule cell signaling is indispensable for normal motor performance.

CACNA1A CACNA1E

6.14e-054112237141091
Pubmed

Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.

ITPR1 ITPR2

6.14e-054112219120137
Pubmed

Blood-brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P-glycoprotein on a novel verapamil influx carrier.

ABCC1 ABCC4

6.14e-054112226507673
Pubmed

Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2

6.14e-054112211163362
Pubmed

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.

CACNA1A CACNA1E

6.14e-054112232616470
Pubmed

Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.

ITPR1 ITPR2

6.14e-054112221424589
Pubmed

Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

ITPR1 ITPR2

6.14e-054112221818117
Pubmed

Celecoxib upregulates multidrug resistance proteins in colon cancer: lack of synergy with standard chemotherapy.

ABCC1 ABCC4

6.14e-054112218690847
Pubmed

Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.

ITPR1 ITPR2

6.14e-054112228615414
Pubmed

MICU2 Restricts Spatial Crosstalk between InsP3R and MCU Channels by Regulating Threshold and Gain of MICU1-Mediated Inhibition and Activation of MCU.

ITPR1 MICU2

6.14e-054112229241542
Pubmed

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.

ITPR1 ITPR2

6.14e-054112210828023
Pubmed

cGMP transport by vesicles from human and mouse erythrocytes.

ABCC1 ABCC4

6.14e-054112217229149
Pubmed

PNPT1, MYO15A, PTPRQ, and SLC12A2-associated genetic and phenotypic heterogeneity among hearing impaired assortative mating families in Southern India.

SLC12A2 MYO15A

6.14e-054112234374074
Pubmed

Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway.

STAT5A CCR2

6.14e-054112222789541
Pubmed

Cocaine Inhibition of Synaptic Transmission in the Ventral Pallidum Is Pathway-Specific and Mediated by Serotonin.

DRD2 HTR1B

6.14e-054112229949769
Pubmed

IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.

ITPR1 ITPR2

6.14e-054112228419336
Pubmed

Identification of QTLs influencing alcohol preference in the High Alcohol Preferring (HAP) and Low Alcohol Preferring (LAP) mouse lines.

DRD2 HTR1B

6.14e-054112216482403
Pubmed

IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming.

ITPR1 ITPR2

6.14e-054112235494252
Pubmed

Mutation screening of the LRIT3, CABP4, and GPR179 genes in Chinese patients with Schubert-Bornschein congenital stationary night blindness.

GRM6 GPR179

6.14e-054112227428514
Pubmed

Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation.

GRM6 GPR179

6.14e-054112222896717
Pubmed

Human skeletal muscle drug transporters determine local exposure and toxicity of statins.

ABCC1 ABCC4

6.14e-054112219940267
Pubmed

Mapping the expression of transient receptor potential channels across murine placental development.

TRPM6 TRPM3 TRPV4

6.26e-0524112333884443
Pubmed

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.

TRPM6 TRPM3 TRPV4

7.10e-0525112316382100
InteractionTTYH1 interactions

SCFD2 DCAKD ABCC4 SLC16A13 DRD2 TMEM186 SLC35F1 ATP13A2 SLC5A3 PIGQ UBE4A SLC12A2 TMEM39A DAGLA

5.28e-1030010514int:TTYH1
InteractionC3orf52 interactions

SCFD2 DCAKD ABCC4 ATP13A2 ITPR2 UBE4A NBAS BMPR1A SLC12A2 TMEM168 TMEM39A DAGLA

6.47e-0830510512int:C3orf52
InteractionZDHHC12 interactions

DCAKD TMEM186 ATP13A2 PIGQ UBE4A NBAS SLC12A2 TMEM39A

2.60e-071231058int:ZDHHC12
InteractionCRELD1 interactions

ABCC4 SLC16A13 DRD2 TMEM186 TMEM104 ATP13A2 SLC5A3 SGPP1

2.21e-061631058int:CRELD1
InteractionMCOLN3 interactions

DCAKD ATP13A2 SGPP1 SLC12A2 DAGLA

2.42e-05661055int:MCOLN3
InteractionEFNA5 interactions

TMEM186 TRHR GPR161 NBAS UTP20

2.80e-05681055int:EFNA5
InteractionOR10H2 interactions

ABCC4 TMEM186 PIGQ SLC12A2 TMEM39A

3.70e-05721055int:OR10H2
InteractionLAMP3 interactions

GPR155 VMP1 ABCC1 MTPAP ITPR2 SLC5A3 SGPP1 ARFGEF3 SLC12A2 SLC39A14 SLC26A11

4.64e-0548610511int:LAMP3
InteractionOTULINL interactions

SCFD2 DCAKD VMP1 ABCC1 ITPR1 ITPR2 UBE4A NBAS SLC12A2 MFSD10

5.08e-0540510510int:OTULINL
InteractionPTPN1 interactions

MCMBP TMEM186 TMEM17 OTUB1 INSRR SLC15A3 STAT5A ITPR2 UBE4A NBAS ZACN SLC12A2

1.00e-0462510512int:PTPN1
InteractionFKBP8 interactions

SCFD2 ABCC1 PTPMT1 TTLL5 INSRR TRRAP ATP13A2 ITPR1 ITPR2 NBAS MYO3B

1.15e-0453810511int:FKBP8
GeneFamilySolute carriers

SLC16A13 SLC22A11 SLC35F1 SLC15A3 SLC45A4 SLC5A3 SLC12A2 SLC39A14 SLC26A11

4.99e-05395789752
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2

5.50e-053782297
GeneFamilyTransient receptor potential cation channels

TRPM6 TRPM3 TRPV4

2.34e-0428783249
GeneFamilyBlood group antigens|XK related family

XKR9 XKR4

9.85e-0411782955
GeneFamilyATP binding cassette subfamily C

ABCC1 ABCC4

1.39e-0313782807
GeneFamilyG protein-coupled receptors, Class A orphans

GPR141 GPR87 GPR161

4.66e-0378783262
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA1E

5.58e-0326782253
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 TRHR INSRR BEST3 LRRC19 TRPM3 GLP1R SEZ6L

1.44e-081741128f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM217 HELQ GPR161 TGM1 TRPM3 GLP1R CNGB3

1.35e-071551127441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM217 INSRR BEST3 TRPM3 GLP1R CNGB3 SEZ6L

3.44e-071781127fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

GPR155 ABCC1 ITPR1 ABCG1 MYO3B KLHL14 SEZ6L

4.80e-0718711277e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

TMEM217 GPR87 AQP5 TGM1 TRPV4 TMEM40

3.23e-06160112618ae6822915d16699beb9047baeef9b006901a35
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

TMEM217 GPR87 AQP5 TGM1 TRPV4 TMEM40

3.23e-061601126830f17bad94de05612fe6d53d39e42a4b3f3e2f3
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCC4 FPR1 GPR141 SLC15A3 CCR2 FCER1G

3.23e-061601126741e3b3f4ec5c77752da54746451f332435226e3
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD83 ABCG1 SLC12A2 SBF2 TRPV4 MYO15A

3.23e-0616011260544bc465af208da448858d6e174ff56f2e08a46
ToppCellPND01-Immune|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FPR1 GPR141 SLC15A3 CCR2 ABCG1 FCER1G

3.59e-06163112698af13bd4257a9da325e1ffe5a254f0f58ca6c4b
ToppCellPND01-Immune-Immune_Myeloid|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FPR1 GPR141 SLC15A3 CCR2 ABCG1 FCER1G

3.59e-061631126ca12d01615be371fe215ec673d4ec787381e0ca6
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 CD83 SLC15A3 TMC3 FCER1G TRPV4

3.99e-06166112603a47b8687f54955e84df1edcb230db332c4ca8f
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD83 SLC15A3 SGPP1 TGM1 FCER1G SERINC3

4.73e-061711126bf475a69db04d4a886e442704955c6a96ff0de46
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSRR BEST3 AQP5 ARFGEF3 ABCG1 SLC12A2

5.40e-0617511260992de1c7bffcb6890584357a7a0a8955927da6c
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCFD2 SIGMAR1 CD83 ITPR1 ARFGEF3 TMEM39A

9.74e-0619411260797245ebfa389a6f66874cb0f11297f1456e600
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCFD2 SIGMAR1 CD83 ITPR1 ARFGEF3 TMEM39A

9.74e-0619411260241b4b88d6210b4c1b8aa99db17115b18142f01
ToppCellBronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FPR1 GPR141 CD83 CCR2 FCER1G KCNK6

1.13e-051991126fdd8c4c04837341e17a4772a2adcdf2f187c56b1
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1E AQP5 ARFGEF3 SLC12A2 TRPV4 KCNK6

1.16e-052001126ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCellfacs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR141 CCR2 FCER1G P2RX2 MYO15A

3.19e-0514411258bd042f12186f36bc5aabf6a0232270a448f4b58
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FPR1 GPR141 SLC15A3 PIGQ FCER1G

3.76e-0514911254de52569611e63a780cde9bd111d6d9c11a05a11
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FPR1 GPR141 SLC15A3 PIGQ FCER1G

3.76e-051491125c957ac23ad6343eacce7e6be4a6d3ac043af4f86
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1H TM6SF2 SGPP1 TRPM3 TMEM236

4.40e-051541125cd99428c282d566b5dbd31fd5a0371b7ffe9ffa2
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 CCR2 FCER1G

4.68e-051561125c841faa1695ff577b0774f531adf1343d05dce9e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 CCR2 FCER1G

4.68e-05156112521baf8c6e62bb7fd1530c2c100f73c0cecee092e
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 TMEM104 ATP13A2 ABCG1 SLC12A2

4.82e-051571125ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellfacs-Lung-Endomucin_-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 GPR141 SLC15A3 TGM1 FCER1G

4.82e-0515711252b60de520edf167f5ca790b478557a778435b3d9
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l1-4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR141 CD83 SLC15A3 CCR2 FCER1G

5.27e-0516011256329b0f02f9509086e563c2ed762a8ec693883b5
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD83 CCR2 FCER1G SERINC3 MYO15A

5.43e-0516111255a8698790f9aba796dd2b64af419055c60bd7de8
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC1 FPR1 TMEM104 ATP13A2 SLC12A2

5.76e-0516311258dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC1 FPR1 TMEM104 ATP13A2 SLC12A2

5.76e-051631125fd243ca223079033be480a24817a399f281fa4d4
ToppCelldroplet-Fat-Mat-18m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 GPR141 SLC15A3 FCER1G TMEM40

5.93e-051641125a27b9b3380f29bb17c9f787423f2591f2b9cf33e
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD83 SLC15A3 ABCG1 SLC12A2 TRPV4

6.28e-05166112591eeb48680dd07ae4115afacdc0a8f6fa18885e5
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 SQOR PIGQ FCER1G TMEM40

6.28e-051661125a1211afc1197d078eb3db0d0f788ecaf4419aa5b
ToppCellhealthy_donor-Myeloid-Monocytic-Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

TRPM6 VMP1 FPR1 TMC3 SLC45A4

6.65e-05168112504259f5a9b067cd1b5619e34591e4b2fccc18535
ToppCelldroplet-Bladder-nan-24m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 CCR2 FCER1G

6.65e-051681125c6e0daa790dd5db20dd1ab8c1e7142484976d743
ToppCelldroplet-Spleen-nan-21m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 SQOR AQP5 CCR2 FCER1G

7.03e-05170112503cb4e508356f85372a588c8d1c6babf2a012683
ToppCelldroplet-Spleen-nan-21m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 SQOR AQP5 CCR2 FCER1G

7.23e-0517111259498c35b2a2c3a339dc8c5d49c8ec20d8ad52753
ToppCelldroplet-Spleen-nan-21m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 SQOR AQP5 CCR2 FCER1G

7.23e-051711125db544252f98e073e5bb4bec4a110cd58e6434435
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FPR1 CD83 SLC15A3 CCR2 FCER1G

7.43e-05172112572fbfa890995e47048b47199c170cc7dcd7661f8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FPR1 CD83 SLC15A3 CCR2 FCER1G

7.43e-0517211252ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 GPR141 SLC15A3 CCR2 FCER1G

7.43e-0517211250457ccc18697aaec44b7c30ae157aae8f48d8785
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 SQOR AQP5 FCER1G GLP1R

7.63e-0517311250f9784b30c81a4a4940e0623cec60d596e9985d2
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ITPR1 SLC5A3 SLC12A2 MYO3B

7.63e-0517311250c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 SQOR AQP5 FCER1G GLP1R

7.63e-05173112560f79e0698a7cf7516690fb20f1b82ee46547699
ToppCelldroplet-Tongue-Unstain-18m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 FCER1G P2RX2

7.84e-0517411259019011eb8d9b7a95804fc11434f0fd42418103a
ToppCelldroplet-Tongue-Unstain-18m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 FCER1G P2RX2

7.84e-051741125deafbd0c2523afe09cc42f8c7b33945f3f5c00b4
ToppCellPCW_13-14-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC35F1 SLC15A3 XKR4 TRPM3 KCNS1

7.84e-0517411250d8e737860120dcd3a6b57992c612595904d585e
ToppCelldroplet-Tongue-Unstain-18m-Myeloid|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 FCER1G P2RX2

7.84e-051741125f2eb0199f59e1e2f46da344c05289876bd254fa3
ToppCelldroplet-Marrow-nan-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR1 SQOR PIGQ FCER1G TMEM40

7.84e-0517411254b749ac9f05776c0c56b74daca833bd0b5704299
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1A AQP5 GPR179 ARFGEF3 DAGLA

8.06e-05175112596219e58dcb327fd27190be78193e7a0d611e62b
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1A AQP5 GPR179 ARFGEF3 DAGLA

8.06e-051751125cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCelldroplet-Tongue-nan-3m-Myeloid|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 FCER1G P2RX2

8.50e-051771125b6c0ab701d9db3f19605b4d23f7e40adca3324e1
ToppCelldroplet-Tongue-nan-3m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 FCER1G P2RX2

8.50e-05177112534bd46704827c9db7053bbd0c671dd0b661b79b4
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

TTLL5 MSANTD2 NBAS TMEM168 SLC39A14

8.50e-05177112582fdd6185b368f54f03de389427cbe3071d21a99
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC35F1 SLC15A3 XKR4 TRPV4 DAGLA

8.50e-0517711250417460bdb012bc43d7254377fa53d79cdab3f34
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR141 SLC15A3 CCR2 ABCG1 FCER1G

8.50e-0517711251e7b4c0e41649d57a2c219a3b7e693538b8b34e4
ToppCelldroplet-Tongue-nan-3m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 FCER1G P2RX2

8.50e-0517711258f4b2f21091d981c12000489054198127098f62c
ToppCellPCW_13-14-Neuronal-Neuronal_SCP|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC35F1 SLC15A3 XKR4 TRPM3 KCNS1

8.50e-051771125621dd82f1393c961d4dd7a615aa52c9df9e36336
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1B GRM6 ITPR1 CCR2 FCER1G

9.44e-0518111257286700396676fdc41d9723979b8b408177aceb9
ToppCelldroplet-Tongue-nan-24m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 FCER1G P2RX2

9.69e-0518211250f06309318c064f0ebdb12a46226b90032290137
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD83 ITPR1 ARFGEF3 SLC12A2 KCNK6

9.94e-051831125ee9c88be88221b7ad4ea9f890b17d6156fb3432e
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD83 ITPR1 ARFGEF3 SLC12A2 KCNK6

9.94e-051831125c52b84034503d931f7b87312d2ff86daff14152d
ToppCellPCW_13-14-Neuronal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC35F1 SLC15A3 XKR4 TRPM3 KCNS1

1.02e-04184112565cf3460125e3dbc34978957bc138a449f71f7df
ToppCellwk_15-18-Hematologic-Myeloid-Myelocyte-like|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TRPM6 FPR1 GPR141 SQOR FCER1G

1.05e-04185112592b9ec18ff7c53a52b87e2c2012d0b719a7ad20a
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A MSANTD2 SI ATP13A2 ARFGEF3

1.05e-041851125d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AQP5 SLC45A4 SGPP1 PIGQ TRPM3

1.07e-041861125aeac0c2db173cd1ea45b5052ab418d6cacd198d8
ToppCelldroplet-Tongue-nan-24m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 FCER1G P2RX2

1.07e-0418611253e16781b9646de971d953da2c49d4210a4c23fe3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FPR1 CD83 SLC15A3 FCER1G DPEP3

1.07e-041861125e4de270d38bbed022f545bd0bbaa9599e707ec87
ToppCelldroplet-Tongue-nan-24m-Myeloid|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR141 CD83 SLC15A3 FCER1G P2RX2

1.07e-041861125298ea4c7f61df65537dfef171ca81d4e976d89c5
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FPR1 GPR141 CD83 CCR2 FCER1G

1.13e-041881125085b61dfad373e5c39f2496539fbfed1b588115a
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR155 BEST3 SLC35F1 AQP5 SEZ6L

1.19e-0419011256c7e1086c0a274cd5527c3104106e372811c9905
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR155 CACNA1E ATP13A2 AQP5 SERINC3

1.31e-041941125ad1aacff97beb76f4211942676e1d5e84087d44e
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR155 CACNA1E ATP13A2 AQP5 SERINC3

1.31e-041941125fdd59b1e036b2d6d8877e1a920a0e56a91a2a882
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CACNA1A FPR1 GRM6 FCER1G MYO15A

1.34e-041951125d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CACNA1A FPR1 GRM6 FCER1G MYO15A

1.34e-04195112519853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellIPF-Myeloid|IPF / Disease state, Lineage and Cell class

FPR1 CD83 ABCG1 FCER1G SBF2

1.34e-041951125fdeb958aeaa00f3fc25c4e59efbbc6f4a572c9ce
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 SGPP1 PIGQ SLC12A2 TRPM3

1.34e-0419511253f517c6fc372bdcaf45b3af373414f13cbebd4ba
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 ITPR1 SLC5A3 SLC12A2 MYO3B

1.34e-041951125a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellControl-Myeloid|Control / Disease state, Lineage and Cell class

FPR1 CD83 ABCG1 FCER1G SBF2

1.34e-04195112546ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCC4 FPR1 CD83 ABCG1 FCER1G

1.37e-041961125e54c08f88779f9fd453a4f5b85aed1f460d8a1e1
ToppCellnormal_Lung-Myeloid_cells|normal_Lung / Location, Cell class and cell subclass

FPR1 CD83 SLC15A3 ABCG1 FCER1G

1.40e-0419711256407aa446a87a9c6fca723718acc19fd3afe06e8
ToppCellTracheal-NucSeq-Stromal-Schwann|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPR155 SLC35F1 SLC15A3 XKR4 TRPM3

1.40e-041971125c1b2a3fbd5f4aeb3555d8c372efc86f1052e7c65
ToppCell343B-Myeloid|343B / Donor, Lineage, Cell class and subclass (all cells)

FPR1 CD83 SLC15A3 ABCG1 FCER1G

1.40e-04197112550c7dff900f806a292b39aade60669b9db882347
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FPR1 CD83 SLC15A3 ABCG1 FCER1G

1.47e-0419911255b6feacb0ca92c3fc6b327be978320426dcf6f68
ToppCellwk_20-22-Hematologic-Myeloid-SPP1+_Mac|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CD83 SLC15A3 ITPR2 FCER1G TMEM236

1.47e-0419911257c19f1b1f4369edd035ca9cdcf4e653771fc4648
ToppCelldistal-3-Hematologic-Alveolar_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FPR1 CD83 SLC15A3 ABCG1 FCER1G

1.47e-041991125f57ba6c711e16fe46f8ddc70223576906b3a710b
ToppCellMild_COVID-19-Myeloid-TRAM3|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

PTPMT1 FPR1 SLC15A3 ABCG1 FCER1G

1.47e-0419911254ab5da8ab757e8294c743949a5374b6e6a388913
ToppCellBAL-Mild-Myeloid-TRAM-TRAM3-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PTPMT1 FPR1 SLC15A3 ABCG1 FCER1G

1.47e-0419911254b88ce864dc75ed8596a076ce4498f73639bbac8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCC4 FPR1 CD83 ITPR2 FCER1G

1.47e-041991125e7faf7d0cb43cf93149c446e5f718f84fa85477c
ToppCellBAL-Mild-Myeloid-TRAM-TRAM3|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PTPMT1 FPR1 SLC15A3 ABCG1 FCER1G

1.47e-041991125bae7aa25f9e23fea19371390b8306e9dc3e4d549
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 SGPP1 PIGQ TRPM3 TRPV4

1.47e-0419911253cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellParenchyma_Control_(B.)-Immune-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

FPR1 CD83 SLC15A3 ABCG1 FCER1G

1.51e-042001125a39886fd2decc81fb698dfd58da996f823bba417
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FPR1 CD83 SLC15A3 ABCG1 FCER1G

1.51e-042001125a443e475e7a10c26a6173d1af961de6219e0e567
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GPR155 FPR1 ITPR2 FCER1G TMEM236

1.51e-0420011254b4df0fe47498310d94448b8a289e58e4f5b5aa8
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm|GW13 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1A MCMBP PIGQ MYO15A DAGLA

1.51e-0420011250f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GPR155 FPR1 SLC15A3 FCER1G TMEM236

1.51e-042001125c210b98a75ab5d899d7278bc9b577f76a0b3970c
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1E AQP5 ARFGEF3 SLC12A2 TRPV4

1.51e-04200112585c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-2|TCGA-Cervix / Sample_Type by Project: Shred V9

GPR155 CACNA1E BEST3 TRPM3

2.32e-041191124d21877baa088440a1e1902bbeb667b977475437a
ToppCellMyeloid-C_(Cd16+_Monocyte)|World / shred on cell class and cell subclass (v4)

FPR1 GPR141 SLC12A2 FCER1G

2.80e-041251124c73a77340e79f73fd1f900724e82a94d82e6b1bf
ToppCellLPS_only-Endothelial-Epi-like|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1E XKR9 XKR4 PIGQ

2.88e-0412611244c598f7bae09aca7a4ecce63dfd6890b26468c73
ToppCellLPS_only-Endothelial-Epi-like-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1E XKR9 XKR4 PIGQ

2.88e-041261124e065304f480a5e38532b66508b0ee87cc48bba9b
Drugfluspirilene

CACNA1A CACNA1E DRD2 HTR1B SIGMAR1

5.98e-07341105CID000003396
DrugAC1L1F6H

CACNA1A CACNA1E NPR1 HTR1B ADCY8 ZACN P2RX2

8.33e-071061107CID000003104
Drugcinuperone

DRD2 HTR1B SIGMAR1

1.09e-0651103CID000133831
DrugPilocarpine

CACNA1A ABCC1 DRD2 HTR1B TRHR SIGMAR1 AQP5 SLC5A3 CCR2 SLC12A2

1.26e-0628511010ctd:D010862
Drugrimonabant

DRD2 HTR1B SIGMAR1 GRM6 TRPV4 DAGLA

3.32e-06841106CID000104849
Drugbaclofen

CACNA1A CACNA1E DRD2 HTR1B SIGMAR1 GRM6 ADCY8 ITPR1

4.18e-061911108CID000002284
DrugAC1L1KS5

CACNA1A CACNA1E NPR1 FPR1 GPR87 GRM6 AQP5 ADCY8 ITPR1 DAGLA

5.17e-0633411010CID000005631
DrugGTP[S]

CACNA1A CACNA1E NPR1 DRD2 HTR1B TRHR SIGMAR1 FPR1 GRM6 KIFC2 ADCY8 ITPR1 TGM1

5.65e-0659111013CID000001764
DrugC13932

TRPM6 CACNA1A DRD2 AQP5 ITPR1 TGM1 TRPM3 TRPV4

7.29e-062061108CID000168297
Drugnitrendipine

CACNA1A CACNA1E ADCY8 ITPR1 ZACN SLC39A14

8.13e-06981106CID000004507
DrugIAA-94

CACNA1A CACNA1E BEST3 ITPR1 SLC12A2

1.15e-05611105CID000003667
DrugN-arachidonoylethanolamine

CACNA1A CACNA1E HTR1B ADCY8 PIGQ ZACN TRPV4 DAGLA

1.43e-052261108CID000002185
DrugURB597

FPR1 ZACN TRPV4 DAGLA

1.67e-05321104CID001383884
DrugMK-771

DRD2 HTR1B TRHR

1.76e-05111103CID000123992
Drughaloperidol

TRPM6 CACNA1A CACNA1E ABCC1 DRD2 HTR1B SIGMAR1 GRM6 ADCY8 TGM1

2.17e-0539411010CID000003559
DrugDPCPX

CACNA1A CACNA1E GRM6 ZDHHC4 ADCY8 P2RX2

2.24e-051171106CID000001329
Drugpo q

FPR1 AQP5

2.31e-0521102CID005289187
DrugS 14506

DRD2 HTR1B SIGMAR1

2.34e-05121103CID000131905
DrugPiperidines

DRD2 SIGMAR1 CCR2

2.34e-05121103ctd:D010880
Drugverapamil

CACNA1A CACNA1E ABCC1 ABCC4 DRD2 ADCY8 ITPR1 ABCG1 MYO3B KCNS1 KCNK6

2.57e-0549011011CID000002520
Drug1,3-dipropylxanthine

CACNA1A CACNA1E GRM6 ADCY8 P2RX2

2.97e-05741105CID000169317
DrugFCE 23884

HTR1B SIGMAR1 ADCY8

3.03e-05131103CID000065898
Drugblonanserin

DRD2 HTR1B SIGMAR1

3.03e-05131103CID000125564
Drugpimozide

CACNA1A CACNA1E DRD2 HTR1B SIGMAR1 ITPR1

3.57e-051271106CID000016362
DrugNSC759576

CACNA1A CACNA1E NPR1 FPR1 ADCY8 ITPR1 GLP1R

4.02e-051911107CID000003075
Drugprazosin

CACNA1A NPR1 DRD2 HTR1B SIGMAR1 ADCY8 P2RX2

4.30e-051931107CID000004893
DrugTyr-D-Ala-Gly-N-methyl-Phe-Gly-ol

CACNA1E DRD2 HTR1B SIGMAR1 ADCY8

4.33e-05801105CID004488326
DrugAC1L1I54

CACNA1A CACNA1E SIGMAR1 ADCY8

4.55e-05411104CID000004426
DrugEthynodiol diacetate [297-76-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A

NPR1 DRD2 FPR1 GRM6 GLP1R KCNS1 DAGLA

4.59e-0519511075024_UP
DrugCyclacillin [3485-14-1]; Up 200; 11.8uM; PC3; HT_HG-U133A

DCAKD PIGQ ABCG1 KCNS1 TRPV4 MYO15A TRAPPC9

4.59e-0519511073800_UP
DrugGI-1

DRD2 HTR1B TRHR SIGMAR1 FPR1 ADCY8

4.62e-051331106CID011957431
DrugTrimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; HL60; HT_HG-U133A

TPRA1 DRD2 TMEM104 STAT5A ITPR2 GLP1R TRAPPC9

5.05e-0519811072146_DN
DrugAlfaxalone [23930-19-0]; Up 200; 12uM; HL60; HT_HG-U133A

DRD2 OTUB1 ABCG1 GLP1R CNGB3 TRAPPC9 SEZ6L

5.05e-0519811073135_UP
DrugBumetanide

ABCC4 SLC22A11 SLC12A2

5.87e-05161103ctd:D002034
Drugpiperazine dihydrochloride

HTR1B TRHR SIGMAR1

5.87e-05161103CID000008893
DrugAC1L1JJR

DRD2 HTR1B SIGMAR1 TRPV4

6.03e-05441104CID000005072
Drugglutamate

TRPM6 CACNA1A CACNA1E NPR1 DRD2 HTR1B PTPMT1 SIGMAR1 GRM6 ADCY8 ITPR1 ZACN TRPM3 P2RX2 TRPV4

6.05e-0596211015CID000000611
DrugS-(2,4-dinitrophenyl)glutathione

ABCC1 ABCC4

6.92e-0531102ctd:C030190
Drug3HPP

CACNA1A DRD2 SIGMAR1

7.10e-05171103CID000000091
Drug2-amino-4-phosphonobutyric acid

CACNA1A CACNA1E HTR1B GRM6 ADCY8

8.03e-05911105CID000002207
DrugWAY-100635

DRD2 HTR1B SIGMAR1 GPR161

9.24e-05491104CID000005684
DrugAC1Q7BEJ

DRD2 HTR1B SIGMAR1 ADCY8

1.00e-04501104CID000001224
DrugRo 41-9067

DRD2 HTR1B ADCY8

1.00e-04191103CID000125800
Drugtiospirone

DRD2 HTR1B SIGMAR1

1.00e-04191103CID000055751
DrugSB 200646A

NPR1 DRD2 HTR1B

1.00e-04191103CID000126769
Druggamma-aminobutyric acid

CACNA1A CACNA1E DRD2 HTR1B SIGMAR1 GRM6 ITPR1 ZACN SLC12A2 P2RX2

1.02e-0447411010CID000000119
DrugAC1L1DXE

CACNA1A CACNA1E HTR1B SIGMAR1 ITPR1 TRPM3 P2RX2 TRPV4

1.04e-042991108CID000002548
Drugcompound 2a

DRD2 TRHR SIGMAR1

1.18e-04201103CID000398803
Drug2-(aminomethyl)pyrrolidine

FPR1 GPR87 CD83 ADCY8 ITPR1 P2RX2

1.33e-041611106CID000072032
DrugGadolinium

TRPM6 DRD2 TRPV4

1.37e-04211103ctd:D005682
Drug3,4-dihydroxyphenylglycine

HTR1B GRM6 ITPR1

1.37e-04211103CID000027915
Drugethyltrimethylammonium

DRD2 ZACN P2RX2

1.37e-04211103CID000033993
Drug8-azidoadenosine 5'-triphosphate

ABCC1 ABCC4

1.38e-0441102ctd:C017040
DrugW50-30

DRD2 HTR1B

1.38e-0441102CID000067500
DrugAC 110

CACNA1A CACNA1E

1.38e-0441102CID000022860
Drugalpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol

DRD2 SIGMAR1

1.38e-0441102ctd:C050408
DrugAC1L7GDJ

ABCC1 ABCC4

1.38e-0441102CID000310029
Drugmyo-inositol

CACNA1A CACNA1E HTR1B TRHR FPR1 GPR87 GRM6 TRRAP ADCY8 ITPR1 FCER1G P2RX2 DAGLA

1.48e-0481111013CID000000892
DrugAC1Q5X3R

ABCC1 ABCC4 ABCG1

1.58e-04221103CID000108075
Drugtrequinsin

ABCC1 ABCC4 NPR1 ADCY8

1.79e-04581104CID000005537
Drugnifedipine

CACNA1A CACNA1E NPR1 SRD5A2 GRM6 ITPR1 TRPM3 MYO3B TRPV4

1.87e-044151109CID000004485
Drugetorphine

CACNA1A CACNA1E SIGMAR1 ADCY8

1.91e-04591104CID000026721
DrugCyclic AMP

ABCC4 DRD2 HTR1B AQP5 ADCY8 GLP1R TRPV4

2.00e-042471107ctd:D000242
Drugethanamine

HTR1B SIGMAR1 TRRAP P2RX2

2.04e-04601104CID000006341
DrugTL-99

DRD2 HTR1B ADCY8

2.06e-04241103CID000122132
Drug3-PPP

DRD2 HTR1B SIGMAR1

2.06e-04241103CID000055445
DrugAC1L3OPK

DRD2 HTR1B SIGMAR1

2.06e-04241103CID000119381
Drugquinoline

ABCC1 ABCC4 HTR1B GPR161

2.18e-04611104CID000007047
Drugcyclophorine

CACNA1A CACNA1E ABCC1 ABCC4 FPR1 CD83 AQP5 ADCY8 ITPR1

2.27e-044261109CID000002909
DrugSDZ 208-911

DRD2 HTR1B

2.29e-0451102CID000148841
DrugRemoxipride

DRD2 SIGMAR1

2.29e-0451102DB00409
Drug6-carboxyfluorescein

ABCC1 SLC22A11

2.29e-0451102ctd:C024098
Drug3-chloro-4-hydroxybenzoate

CACNA1A ZDHHC4

2.29e-0451102CID000019860
DrugEmd 23448

DRD2 HTR1B

2.29e-0451102CID000126443
Drugmazapertine

DRD2 HTR1B

2.29e-0451102CID000060819
Drugpipotiazine

DRD2 HTR1B

2.29e-0451102CID000062867
Drug1-stearoyl-2-arachidonoylglycerol

TRPM6 DAGLA

2.29e-0451102ctd:C075809
DrugN-n-propylnorapomorphine

DRD2 HTR1B ADCY8

2.34e-04251103CID000030137
Drugtetradotoxin

CACNA1A CACNA1E NPR1 DRD2 HTR1B SIGMAR1 GRM6 P2RX2 TRPV4

2.35e-044281109CID000020382
DrugL-quisqualic acid

HTR1B SIGMAR1 GRM6 ADCY8 ITPR1 ZACN

2.44e-041801106CID000001209
DrugTacrolimus

TRPM6 NPR1 DRD2 SQOR ITPR1 TGM1 GLP1R SERINC3

2.44e-043391108ctd:D016559
DrugCAS 66104-23-2

DRD2 HTR1B SIGMAR1 ADCY8

2.47e-04631104CID000004745
Drugamsonine

CACNA1A CACNA1E DRD2 HTR1B SIGMAR1 ADCY8

2.51e-041811106CID000002866
DrugGF109203X

CACNA1A CACNA1E NPR1 GRM6 ADCY8 ITPR1 TGM1 DAGLA

2.54e-043411108CID000002396
DrugNSC7524

CACNA1A CACNA1E DRD2 HTR1B ADCY8 ITPR1

2.59e-041821106CID000005657
Drugpropranolol

CACNA1A CACNA1E NPR1 DRD2 HTR1B CD83 ADCY8 ITPR1 DAGLA

2.60e-044341109CID000004946
Drug8-OH-DPAT

DRD2 HTR1B SIGMAR1 ADCY8 BMPR1A

2.62e-041171105CID000001220
DrugAC1NBU2S

CACNA1A CACNA1E NPR1 TRHR ITPR1

2.62e-041171105CID004473765
DrugAC1L9K24

ADCY8 PIGQ CDAN1 TGM1

2.62e-04641104CID000444222
DrugAC1NE3ZR

ABCC1 ABCC4 BMPR1A

2.63e-04261103CID004636208
Drugmosapride

DRD2 HTR1B TGM1

2.63e-04261103CID000119583
Drug2-arachidonoylglycerol (2-AG

SIGMAR1 GPR87 GRM6 TRPV4 DAGLA

2.83e-041191105CID000001541
DrugRU 24926

DRD2 HTR1B ADCY8

2.95e-04271103CID000122203
DrugAC1L1TJF

CACNA1A CACNA1E DRD2 ADCY8

2.95e-04661104CID000003377
DrugAC1L1HE1

DRD2 HTR1B SIGMAR1 ADCY8

3.13e-04671104CID000004090
Drugarabinosyladenine

DCAKD CACNA1A CACNA1E ABCC1 NPR1 DRD2 HTR1B SIGMAR1 GRM6 ADCY8 ITPR1 P2RX2

3.17e-0476211012CID000000191
Drug3-isoreserpine

ABCC1 ABCC4 DRD2 HTR1B ADCY8 ABCG1

3.26e-041901106CID000005052
DrugAC1L1BOS

DRD2 HTR1B SIGMAR1

3.29e-04281103CID000051767
DrugTexas Red

ABCC1 ABCC4 TGM1

3.29e-04281103CID000452705
Drugaptiganel

SIGMAR1 GRM6 ZACN

3.29e-04281103CID000060839
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

1.30e-0521072C1140716
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

1.30e-0521072C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

1.30e-0521072C1527348
DiseaseAnoxia of brain

ITPR1 ITPR2

1.30e-0521072C0995195
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1A CACNA1E

3.90e-0531072DOID:0111181 (implicated_via_orthology)
Diseasemigraine (implicated_via_orthology)

CACNA1A CACNA1E

7.78e-0541072DOID:6364 (implicated_via_orthology)
DiseaseGlobal developmental delay

CACNA1E TRRAP PIGQ NBAS TRPM3

1.27e-041331075C0557874
DiseaseSeizures

CACNA1E DRD2 HTR1B SIGMAR1 TRRAP TRPM3

1.47e-042181076C0036572
Diseasemigraine with aura (is_implicated_in)

CACNA1A DRD2

1.94e-0461072DOID:10024 (is_implicated_in)
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A CACNA1E

2.70e-0471072DOID:0050951 (implicated_via_orthology)
Diseasehyperprolactinemia (biomarker_via_orthology)

DRD2 SRD5A2

4.61e-0491072DOID:12700 (biomarker_via_orthology)
DiseaseCharcot-Marie-Tooth disease

KIF1B SBF2 TRPV4

4.80e-04421073cv:C0007959
DiseaseMemory impairment

DRD2 SIGMAR1 TRPV4

5.51e-04441073C0233794
DiseaseHypertensive disease

ABCC1 NPR1 DRD2 SLC12A2 GLP1R

6.56e-041901075C0020538
Diseasedaytime rest measurement

CACNA1A TRHR TMEM225B SQOR SLC45A4 TRPM3

7.37e-042951076EFO_0007828
DiseaseNight blindness, congenital stationary, type 1

GRM6 GPR179

8.40e-04121072C3501847
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2

8.40e-04121072DOID:1441 (implicated_via_orthology)
DiseaseNight Blindness, Congenital Stationary, Type 1A

GRM6 GPR179

8.40e-04121072C3495587
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)

GRM6 GPR179

8.40e-04121072C1864877
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B

GRM6 GPR179

8.40e-04121072C1850362
DiseaseX-Linked Csnb

GRM6 GPR179

8.40e-04121072C3711543
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A

GRM6 GPR179

8.40e-04121072C1848172
DiseaseCone-rod synaptic disorder, congenital nonprogressive

GRM6 GPR179

9.90e-04131072C4041558
DiseaseManganese Poisoning

ATP13A2 SLC39A14

1.15e-03141072C0677050
Diseasebreast carcinoma

SCFD2 VMP1 ABCC4 KIF1B TMEM104 ADCY8 ITPR1 GPR161 SLC12A2 SBF2 KLHL14

1.19e-03101910711EFO_0000305
Diseasehypertension (implicated_via_orthology)

NPR1 TRHR SLC12A2 GLP1R

1.23e-031281074DOID:10763 (implicated_via_orthology)
Diseaseanthranilic acid measurement

KIF1B MYO3B

1.51e-03161072EFO_0010460
DiseaseNight blindness, congenital stationary

GRM6 GPR179

1.71e-03171072C0339535
DiseaseCharcot-Marie-Tooth disease type 2

KIF1B TRPV4

1.71e-03171072cv:C0270914
DiseaseBipolar Disorder

CACNA1A DRD2 HTR1B ADCY8 ITPR1 SLC5A3 SEZ6L

1.80e-034771077C0005586
Diseasecalcium measurement

SCFD2 TRPM6 ABCC4 TM6SF2 ITPR1 SLC12A2 PIP5K1A KCNK6

2.07e-036281078EFO_0004838
DiseaseAmphetamine-Related Disorders

DRD2 HTR1B TRPM3

2.59e-03751073C0236733
DiseaseAmphetamine Abuse

DRD2 HTR1B TRPM3

2.59e-03751073C0236807
DiseaseAmphetamine Addiction

DRD2 HTR1B TRPM3

2.59e-03751073C0236804
Diseaselevel of Phosphatidylcholine (18:1_20:4) in blood serum

TM6SF2 DAGLA

2.62e-03211072OBA_2045104
Diseaselevel of Phosphatidylcholine (16:0_20:4) in blood serum

TM6SF2 DAGLA

2.62e-03211072OBA_2045076
Diseaseepilepsy (implicated_via_orthology)

CACNA1A CACNA1E SLC12A2 SBF2

2.98e-031631074DOID:1826 (implicated_via_orthology)
DiseaseEtat Marbre

DRD2 SLC12A2

3.14e-03231072C0266487
DiseaseAbnormality of refraction

TPRA1 TM6SF2 SLC45A4 ITPR2 BMPR1A DPEP3 CNGB3 DAGLA

3.17e-036731078HP_0000539
DiseaseMood Disorders

DRD2 HTR1B SIGMAR1 ADCY8

3.32e-031681074C0525045

Protein segments in the cluster

PeptideGeneStartEntry
LLYREFIVFAVLYTA

BEST3

31

Q8N1M1
LLTETVYAGLFLRYD

ADCY8

871

P40145
IYFIVLTLFGNYTLL

CACNA1A

691

O00555
TLLLIALYGRIYVEA

HTR1B

221

P28222
IYFIVLTLFGNYTLL

CACNA1E

681

Q15878
GIFFISLRLIAYFVL

ABCG1

656

P45844
LSLLGILIVSFFIYR

NPR1

481

P16066
VVPLLEYYRDIFTLL

CDAN1

706

Q8IWY9
IVGAVLAAILYFYLL

AQP5

211

P55064
RIIYCYLGIAEVRTL

MSANTD2

471

Q6P1R3
LTFLFYVVILVTRYL

GPR141

101

Q7Z602
ARVVYDLLFYFIVII

ITPR2

2516

Q14571
LRITFDYTLPLVLLY

MSL3P1

186

P0C860
RALYKVLVTVYLFLG

KCNK6

231

Q9Y257
YRAEIVLLLALVIFY

CD83

141

Q01151
SLRRLGLVYFLYLFL

MFSD10

271

Q14728
VVVYTFLAVLLYLSA

MYADML2

231

A6NDP7
FAIVYGTIILKLYRV

GPR179

456

Q6PRD1
ALILVYLFSIVGYLF

ITPR1

2456

Q14643
LVLVSRLYYPEIFRA

SBF2

121

Q86WG5
FERNLIYTYIGSILV

MYO15A

1246

Q9UKN7
VEGVYLYTLLAFSVL

GLP1R

246

P43220
VGQILVFVLLYSSLY

GPR155

441

Q7Z3F1
ILVGRAFVYLSNLLY

KIF1B

971

O60333
EEVFIYTPLLSYLRL

LRRC17

146

Q8N6Y2
VLDYLIIFISYVLIL

OR51B5

206

Q9H339
YFLLSQLSLRDILYI

OR2T7

51

P0C7T2
LVFILLSYSYIVRAV

OR2W3

211

Q7Z3T1
VLLLSYVFILYTIRA

OR4P4

211

Q8NGL7
YILDAILFLYGIVLT

FCER1G

26

P30273
LRITFDYTLPLVLLY

MSL3

261

Q8N5Y2
HSYREVGILLLYLAV

KCNS1

371

Q96KK3
RIALTSSELLYIYGA

MTPAP

331

Q9NVV4
LLVINYRGELRSYLV

NBAS

201

A2RRP1
LLLYIGIIDILQSYR

PIP5K1A

396

Q99755
YTSIVFLGLISIDRY

GPR87

126

Q9BY21
GLIILSYALILYSVL

OR56B2P

221

Q8NGI1
VLFGIARSLLVFYVL

ABCC4

776

O15439
LARVLFYPTLLYTLF

PTPMT1

11

Q8WUK0
LGVLYRAVQLLILLY

P2RX2

41

Q9UBL9
LVVYLRLLTSGYLQR

OTUB1

171

Q96FW1
ALLGTIYSIFILYRN

ATP13A2

436

Q9NQ11
RELSYVLLTGIFLIY

GRM6

621

O15303
SSIGLRLVLEYLYTA

KLHL14

131

Q9P2G3
TLSIIGYLIFYIIHR

CASD1

321

Q96PB1
GYRYVILDIPLLFET

DCAKD

106

Q8WVC6
TIYYIAAELVRLVGS

ARFGEF3

321

Q5TH69
IYIRLLGAYLFIISR

BMPR1A

6

P36894
GGIFFIILLTIDRYL

CCR2

126

P41597
LTQVTDYLLLFRVYG

INSRR

76

P14616
DYLLLFRVYGLESLR

INSRR

81

P14616
YVLYVRLAILVIEFI

DAGLA

96

Q9Y4D2
LTLGVIAIDRYYAVL

GPR161

116

Q8N6U8
GLQYYSTLLDALVLR

KLB

171

Q86Z14
YYATLLTLLIAVIVF

DRD2

36

P14416
SVLRSFYVLGVRYLT

DPEP3

206

Q9H4B8
VVNRLYLSFVLYTLL

HELQ

931

Q8TDG4
LLISYYGLVFDLQSL

SLC22A11

356

Q9NSA0
VYLGRYRAVALSLLL

SLC15A3

96

Q8IY34
TFYKRLLLYFIALAI

SLC39A14

181

Q15043
SLLIYIFYSLFRRDG

KIFC2

6

Q96AC6
TRVLQTYFLLTELYL

LRRC19

66

Q9H756
FRIYLTLLRFLEYSI

MCMBP

551

Q9BTE3
LRILYGVLFLLIYLA

OR14A2

21

Q96R54
RDITFYVYFSLLLIQ

ABCC1

171

P33527
YLDYSTPILILDLLV

TAAR3P

281

Q9P1P4
SVLLLTDLYYQRLAL

UTP20

601

O75691
ISYRYLIIALGIQLD

SQOR

136

Q9Y6N5
LIISLLLGGAYIYIT

SEZ6L

966

Q9BYH1
VLLSLAGSIYLIYFV

TMC3

326

Q7Z5M5
LARVLVLYLGNLYSL

TMC3

396

Q7Z5M5
LATVLYGFIARILFL

TRHR

206

P34981
YIILGRVFLLSAVFL

TMEM225B

71

P0DP42
GYLFLDIITYLVFAV

FPR1

21

P21462
PTTALYYLVFTLLRL

PIGQ

461

Q9BRB3
YYLVFTLLRLLVVAV

PIGQ

466

Q9BRB3
GLISYTEYLFLLTIL

MICU2

156

Q8IYU8
IAGFLYTILILAVFY

SGPP1

261

Q9BX95
FLTLFYTLRSYARGL

SIGMAR1

196

Q99720
RIQVYFAALSLILYI

SLC5A3

121

P53794
LLILLIYIYSVTGEL

SCFD2

471

Q8WU76
IVTYRVTGGILDFYI

SI

311

P14410
LADRLGDLSYLIYVF

STAT5A

656

P42229
YRVIRTTGYLLFILH

CNGB3

351

Q9NQW8
YDLSVRVIYVLGTLG

SLC45A4

586

Q5BKX6
YILLFLVYTTTLAVR

SLC35F1

101

Q5T1Q4
LITLIEAIRLYLGYV

TMEM17

86

Q86X19
LLLLYEDIGTSRVRY

TPRA1

31

Q86W33
YRITLIDIGLVVEYL

TRPM6

506

Q9BX84
FLRYTVALTLINTGY

SLC16A13

216

Q7RTY0
VLVLLSLDYLTSLFY

SLC26A11

386

Q86WA9
LIEGSVVFYQLYSLL

TMEM39A

426

Q9NV64
YRISLIDIGLVIEYL

TRPM3

576

Q9HCF6
IRYFLIYVLTLTASA

ZDHHC4

191

Q9NPG8
LLTYVIVLGLYIYVT

SLC12A2

736

P55011
SLETVGIYFGLVYRI

TMEM40

196

Q8WWA1
SYFLRRLVGILYLNE

TMEM186

121

Q96B77
DAYRIYLAIFTLLLG

TMEM104

206

Q8NE00
LVFLDYVLILAFYGL

TMEM104

306

Q8NE00
YIIDYYGTRLTRLSI

TM2D1

181

Q9BX74
RLFIYYFVILLENTA

XKR4

456

Q5GH76
YTDIRFSLGVFLFIL

SRD5A2

141

P31213
SSVRYLGYLARINLL

TMEM168

31

Q9H0V1
IYAFILLLSTVVSYI

SERINC3

41

Q13530
RIGYKVTLLLSYLVL

ZACN

261

Q401N2
VGSVEILLSYLRTGY

TGM1

356

P22735
QRYSILSELYELIGF

TRAPPC9

386

Q96Q05
LVIYLILAGFFTLFR

TM6SF2

221

Q9BZW4
LALTEYTLYLGFHRL

UBE4A

511

Q14139
FLLYSVYAQIFRGLV

TMEM217

81

Q8N7C4
DSLRIYLLQYATLLV

TRRAP

1826

Q9Y4A5
LLYFIYSVLVIVSAA

TRPV4

551

Q9HBA0
LYPVYIFSFISLLRI

TMEM236

266

Q5W0B7
LVIYLYEEGLARFAT

TTLL5

236

Q6EMB2
VLTLLLGILFLIVYY

XKR9

326

Q5GH70
SFLLLLAVLIATYYV

VMP1

81

Q96GC9
FSENLIYTYIGTLLV

MYO1H

36

Q8N1T3
RYADLLIYTYVGDIL

MYO3B

366

Q8WXR4