Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionproteoglycan binding

LRP1 ITGA2 CTSB AGRN

9.85e-0751304GO:0043394
GeneOntologyMolecularFunctionNotch binding

ATRNL1 MEGF10 NOTCH4

8.74e-0627303GO:0005112
GeneOntologyMolecularFunctionscavenger receptor activity

LRP1 MEGF10 EGFEM1P

8.74e-0627303GO:0005044
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

LRP1 ITGA2 AGRN

1.09e-0529303GO:0043395
GeneOntologyMolecularFunctionextracellular matrix structural constituent

MUC3A SSPOP LTBP4 AGRN

1.72e-04188304GO:0005201
GeneOntologyMolecularFunctioncargo receptor activity

LRP1 MEGF10 EGFEM1P

2.78e-0485303GO:0038024
GeneOntologyMolecularFunctionadenylate cyclase activity

ADCY5 GUCY2D

3.29e-0418302GO:0004016
GeneOntologyMolecularFunctioncyclase activity

ADCY5 GUCY2D

5.90e-0424302GO:0009975
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

ADCY5 GUCY2D

6.41e-0425302GO:0016849
GeneOntologyMolecularFunctiontransforming growth factor beta binding

LTBP4 AGRN

6.93e-0426302GO:0050431
GeneOntologyMolecularFunctioncalcium ion binding

LRP1 PRSS1 LTBP4 AGRN EGFEM1P NOTCH4

7.50e-04749306GO:0005509
GeneOntologyMolecularFunctionlaminin binding

ITGA2 AGRN

1.19e-0334302GO:0043236
GeneOntologyMolecularFunctionintegrin binding

ITGA2 LTBP4 TSPAN8

2.26e-03175303GO:0005178
GeneOntologyMolecularFunctionextracellular matrix binding

ITGA2 AGRN

5.37e-0373302GO:0050840
GeneOntologyMolecularFunctioncollagen binding

ITGA2 CTSB

6.57e-0381302GO:0005518
GeneOntologyBiologicalProcesscollagen metabolic process

PRSS1 PLOD3 ITGA2 CTSB

6.03e-05148304GO:0032963
GeneOntologyBiologicalProcessextracellular matrix organization

LRP1 PRSS1 PLOD3 ITGA2 LTBP4

1.94e-04377305GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

LRP1 PRSS1 PLOD3 ITGA2 LTBP4

1.97e-04378305GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

LRP1 PRSS1 PLOD3 ITGA2 LTBP4

1.99e-04379305GO:0045229
GeneOntologyBiologicalProcessendothelial cell morphogenesis

PLOD3 NOTCH4

2.12e-0415302GO:0001886
GeneOntologyCellularComponentextracellular matrix

PRSS1 PLOD3 FCGBP CTSB SSPOP LTBP4 AGRN

3.15e-05656307GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

PRSS1 PLOD3 FCGBP CTSB SSPOP LTBP4 AGRN

3.21e-05658307GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

PRSS1 PLOD3 CTSB SSPOP LTBP4 AGRN

9.13e-05530306GO:0062023
DomainEGF_3

LRP1 ATRN TENM3 MUC3A SSPOP LTBP4 AGRN ATRNL1 MEGF10 NOTCH4

8.84e-132352810PS50026
DomainEGF

LRP1 ATRN FCGBP TENM3 MUC3A LTBP4 AGRN ATRNL1 MEGF10 NOTCH4

8.84e-132352810SM00181
DomainEGF-like_dom

LRP1 ATRN FCGBP TENM3 MUC3A LTBP4 AGRN ATRNL1 MEGF10 NOTCH4

1.57e-122492810IPR000742
DomainEGF_1

LRP1 ATRN TENM3 MUC3A SSPOP LTBP4 AGRN ATRNL1 MEGF10 NOTCH4

2.00e-122552810PS00022
DomainEGF_2

LRP1 ATRN TENM3 MUC3A SSPOP LTBP4 AGRN ATRNL1 MEGF10 NOTCH4

2.93e-122652810PS01186
DomainEGF-like_CS

LRP1 ATRN TENM3 MUC3A LTBP4 AGRN ATRNL1 MEGF10 NOTCH4

9.70e-11261289IPR013032
DomainEGF_Lam

ATRN AGRN ATRNL1 MEGF10

2.05e-0735284SM00180
DomainLaminin_EGF

ATRN AGRN ATRNL1 MEGF10

2.88e-0738284IPR002049
DomainEGF_extracell

ATRN TENM3 ATRNL1 MEGF10

1.86e-0660284IPR013111
DomainEGF_2

ATRN TENM3 ATRNL1 MEGF10

1.86e-0660284PF07974
DomainEGF_LAM_2

ATRN AGRN ATRNL1

1.19e-0530283PS50027
DomainEGF_LAM_1

ATRN AGRN ATRNL1

1.19e-0530283PS01248
DomainLaminin_EGF

ATRN AGRN MEGF10

1.91e-0535283PF00053
DomainLDLR_class-A_CS

LRP1 LRP3 SSPOP

2.87e-0540283IPR023415
DomainEGF_CA

LRP1 LTBP4 AGRN NOTCH4

3.14e-05122284SM00179
DomainEGF-like_Ca-bd_dom

LRP1 LTBP4 AGRN NOTCH4

3.35e-05124284IPR001881
DomainEGF

LRP1 ATRN AGRN NOTCH4

3.57e-05126284PF00008
DomainLdl_recept_a

LRP1 LRP3 SSPOP

4.10e-0545283PF00057
Domain-

LRP1 LRP3 SSPOP

4.39e-05462834.10.400.10
DomainLDLRA_1

LRP1 LRP3 SSPOP

4.99e-0548283PS01209
DomainLDrepeatLR_classA_rpt

LRP1 LRP3 SSPOP

5.31e-0549283IPR002172
DomainLDLa

LRP1 LRP3 SSPOP

5.31e-0549283SM00192
DomainCUB

LRP3 ATRN ATRNL1

5.31e-0549283PF00431
DomainLDLRA_2

LRP1 LRP3 SSPOP

5.31e-0549283PS50068
DomainCUB

LRP3 ATRN ATRNL1

5.64e-0550283SM00042
Domain-

LRP3 ATRN ATRNL1

6.35e-05522832.60.120.290
DomainCUB

LRP3 ATRN ATRNL1

6.72e-0553283PS01180
DomainGrowth_fac_rcpt_

LRP1 ATRN LTBP4 NOTCH4

8.20e-05156284IPR009030
DomainCUB_dom

LRP3 ATRN ATRNL1

8.36e-0557283IPR000859
DomainFol_N

FCGBP AGRN

1.18e-0411282IPR003645
DomainFOLN

FCGBP AGRN

1.18e-0411282SM00274
DomainTIL

FCGBP SSPOP

1.42e-0412282PF01826
DomainC8

FCGBP SSPOP

1.42e-0412282PF08742
DomainUnchr_dom_Cys-rich

FCGBP SSPOP

1.67e-0413282IPR014853
DomainC8

FCGBP SSPOP

1.67e-0413282SM00832
DomainSEA

MUC3A AGRN

1.95e-0414282SM00200
DomainTIL_dom

FCGBP SSPOP

1.95e-0414282IPR002919
DomainVWFD

FCGBP SSPOP

2.57e-0416282PS51233
DomainVWD

FCGBP SSPOP

2.57e-0416282SM00216
DomainVWF_type-D

FCGBP SSPOP

2.57e-0416282IPR001846
DomainVWD

FCGBP SSPOP

2.57e-0416282PF00094
DomainEGF_CA

LRP1 LTBP4 NOTCH4

2.84e-0486283PF07645
DomainA/G_cyclase_CS

ADCY5 GUCY2D

2.91e-0417282IPR018297
DomainEMI

SSPOP MEGF10

2.91e-0417282PS51041
DomainNucleotide_cyclase

ADCY5 GUCY2D

3.27e-0418282IPR029787
Domain-

ADCY5 GUCY2D

3.27e-04182823.30.70.1230
DomainGUANYLATE_CYCLASE_2

ADCY5 GUCY2D

3.65e-0419282PS50125
DomainVWC_out

FCGBP SSPOP

3.65e-0419282SM00215
DomainGUANYLATE_CYCLASE_1

ADCY5 GUCY2D

3.65e-0419282PS00452
DomainA/G_cyclase

ADCY5 GUCY2D

3.65e-0419282IPR001054
DomainCYCc

ADCY5 GUCY2D

3.65e-0419282SM00044
DomainGuanylate_cyc

ADCY5 GUCY2D

3.65e-0419282PF00211
DomainEGF_Ca-bd_CS

LRP1 LTBP4 NOTCH4

4.05e-0497283IPR018097
DomainEGF_CA

LRP1 LTBP4 NOTCH4

4.30e-0499283PS01187
DomainASX_HYDROXYL

LRP1 LTBP4 NOTCH4

4.43e-04100283PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1 LTBP4 NOTCH4

5.25e-04106283IPR000152
DomainSEA

MUC3A AGRN

5.38e-0423282PS50024
DomainSEA_dom

MUC3A AGRN

5.38e-0423282IPR000082
DomainhEGF

MEGF10 NOTCH4

8.00e-0428282PF12661
DomainPlexin_repeat

ATRN ATRNL1

1.05e-0332282IPR002165
DomainPSI

ATRN ATRNL1

1.05e-0332282PF01437
DomainVWC

FCGBP SSPOP

1.47e-0338282SM00214
Domain-

LRP1 TENM3

1.55e-03392822.120.10.30
DomainVWF_dom

FCGBP SSPOP

1.80e-0342282IPR001007
DomainPSI

ATRN ATRNL1

1.97e-0344282IPR016201
DomainPSI

ATRN ATRNL1

2.15e-0346282SM00423
Domain6-blade_b-propeller_TolB-like

LRP1 TENM3

2.15e-0346282IPR011042
Domain-

ATRN ATRNL1

2.34e-03482822.120.10.80
DomainKelch-typ_b-propeller

ATRN ATRNL1

3.06e-0355282IPR015915
DomainKelch_1

ATRN ATRNL1

4.91e-0370282PF01344
DomainKelch_1

ATRN ATRNL1

4.91e-0370282IPR006652
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

PRSS1 PLOD3 ITGA2 CTSB LTBP4 AGRN

7.88e-07258196MM14572
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

PRSS1 PLOD3 ITGA2 CTSB LTBP4 AGRN

1.90e-06300196M610
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC3A SSPOP AGRN NOTCH4

3.50e-05143194M27275
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC3A SSPOP NOTCH4

9.84e-0568193M27303
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP1 AGRN GUCY2D

2.42e-0492193MM14881
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC3A SSPOP AGRN NOTCH4

3.03e-04250194M27554
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP1 AGRN GUCY2D

3.09e-04100193M27158
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

PRSS1 PLOD3 CTSB SSPOP LTBP4 AGRN

8.00e-0917530628071719
Pubmed

Cathepsin B activates human trypsinogen 1 but not proelastase 2 or procarboxypeptidase B.

PRSS1 CTSB

7.19e-07230216534247
Pubmed

A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation.

PRSS1 CTSB

7.19e-07230230487519
Pubmed

Genetic analysis of attractin homologs.

ATRN ATRNL1

7.19e-07230218064672
Pubmed

Cerulein-induced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice.

PRSS1 CTSB

7.19e-07230223354015
Pubmed

Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis.

PRSS1 CTSB

7.19e-07230211932257
Pubmed

CaMKII/proteasome/cytosolic calcium/cathepsin B axis was present in tryspin activation induced by nicardipine.

PRSS1 CTSB

2.16e-06330231221819
Pubmed

SPARC promotes cathepsin B-mediated melanoma invasiveness through a collagen I/α2β1 integrin axis.

ITGA2 CTSB

4.31e-06430221850018
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

PRSS1 CTSB LTBP4 AGRN

5.50e-0613530428675934
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

LRP1 ATRN EWSR1 TTC13 PLOD3 ITGA2 TENM3 AGRN

5.87e-06120130835696571
Pubmed

Genetic and phenotypic studies of the dark-like mutant mouse.

ATRN ATRNL1

7.18e-06530218821597
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 LRP3

7.18e-06530219047013
Pubmed

Cloning and characterization of hurpin (protease inhibitor 13): A new skin-specific, UV-repressible serine proteinase inhibitor of the ovalbumin serpin family.

PRSS1 CTSB

1.08e-05630210512713
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

LRP1 ATRN TTC13 PLOD3 CTSB LTBP4

1.21e-0561330622268729
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

PLOD3 CTSB LTBP4 AGRN

1.27e-0516730422159717
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

CTSB SSPOP AGRN

2.33e-056430322261194
Pubmed

Agrin has a pathological role in the progression of oral cancer.

PRSS1 EWSR1 TENM3 AGRN

2.44e-0519730429872149
Pubmed

APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice.

LRP1 AGRN

2.58e-05930223986861
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

LRP1 SSPOP ATRNL1

3.18e-057130333541421
Pubmed

High-resolution linkage map of mouse chromosome 13 in the vicinity of the host resistance locus Lgn1.

ITGA2 NAIP

3.22e-05103029119362
Pubmed

Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch.

TENM3 MEGF10

7.50e-051530231812516
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ATRN SSPOP ATRNL1

1.02e-041053039628581
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

LRP1 LTBP4 AGRN

1.45e-0411830321078624
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

ARMCX4 ADCY5

1.96e-042430232212159
Pubmed

ERp57 is essential for efficient folding of glycoproteins sharing common structural domains.

ITGA2 AGRN

2.13e-042530217170699
Pubmed

Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.

ADCY5 TSPAN8

2.49e-042730220490451
Pubmed

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.

LRP1 EWSR1 CTSB

2.87e-0414930326370502
Pubmed

Functional analysis of secreted and transmembrane proteins critical to mouse development.

ATRN AGRN

3.29e-043130211431694
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

LRP1 PLOD3 AGRN

3.81e-0416430332409323
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

LRP3 TTC13 PLOD3 CTSB

4.90e-0443030416303743
Pubmed

Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.

ADCY5 TSPAN8

5.78e-044130220889853
Pubmed

Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.

PRSS1 EWSR1 PLOD3

6.49e-0419730323686814
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

LRP1 ATRN EWSR1 ARMCX4 CTSB ATRNL1

6.97e-04128530635914814
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

ITGA2 AGRN

8.59e-045030223658023
InteractionFBXO2 interactions

ATRN TTC13 PLOD3 ITGA2 TENM3 LTBP4 AGRN

1.48e-06411297int:FBXO2
InteractionCFC1 interactions

TTC13 ITGA2 LTBP4 AGRN

3.07e-05126294int:CFC1
InteractionZNF408 interactions

ATRN FSD2 ZNF526 LTBP4

5.31e-05145294int:ZNF408
InteractionFBXO6 interactions

LRP1 ATRN TTC13 PLOD3 CTSB LTBP4 AGRN

5.52e-05717297int:FBXO6
InteractionZFP41 interactions

LRP1 LTBP4 AGRN

7.44e-0557293int:ZFP41
InteractionMANEA interactions

LRP3 ATRN AGRN

8.68e-0560293int:MANEA
InteractionSDF2L1 interactions

ATRN EWSR1 TTC13 CTSB AGRN

8.75e-05322295int:SDF2L1
InteractionC1orf54 interactions

TTC13 ITGA2 TENM3 AGRN

9.19e-05167294int:C1orf54
InteractionAPOE interactions

LRP1 KLK10 CTSB AGRN

1.01e-04171294int:APOE
InteractionATN1 interactions

EWSR1 SSPOP LTBP4 AGRN

1.42e-04187294int:ATN1
Cytoband7q22

PLOD3 MUC3A

2.86e-04383027q22
CytobandEnsembl 112 genes in cytogenetic band chr19q13

LRP3 ZNF526 KLK10 FCGBP LTBP4

9.72e-041192305chr19q13
GeneFamilyLow density lipoprotein receptors

LRP1 LRP3

1.31e-0413242634
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

ATRN ATRNL1

1.34e-03412421298
CoexpressionTRAVAGLINI_LUNG_MUCOUS_CELL

KLK10 FCGBP CTSB TSPAN8

1.23e-05125304M41656
CoexpressionNABA_MATRISOME

PRSS1 PLOD3 CTSB SSPOP LTBP4 AGRN MEGF10 EGFEM1P

1.28e-051008308MM17056
CoexpressionNABA_MATRISOME

PRSS1 PLOD3 CTSB MUC3A SSPOP LTBP4 AGRN MEGF10

1.46e-051026308M5889
CoexpressionNABA_MATRISOME_HGSOC_OMENTAL_METASTASIS

PLOD3 CTSB AGRN

4.21e-0559303M47993
CoexpressionNABA_ECM_GLYCOPROTEINS

SSPOP LTBP4 AGRN EGFEM1P

6.46e-05191304MM17059
CoexpressionJOHNSTONE_PARVB_TARGETS_3_UP

LRP1 SPAG4 ITGA2 CTSB AGRN

1.22e-04433305M2240
CoexpressionBUSSLINGER_DUODENAL_PANETH_CELLS

PRSS1 FCGBP

1.32e-0415302M40030
ToppCellBiopsy_Control_(H.)-Epithelial-KRT5-/KRT17+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

LRP3 PRSS1 ITGA2 MUC3A AGRN

2.10e-071993053b1f56c8b40bb36922a31d2d440a8c468a8aa3f1
ToppCellfacs-MAT-Fat-18m-Epithelial-epithelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FSD2 MAP3K13 ITGA2 TSPAN8

2.59e-06144304fd852095dcd716ac53b0fd25d83e6f454b2ae794
ToppCellfacs-MAT-Fat-18m-Epithelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FSD2 MAP3K13 ITGA2 TSPAN8

2.59e-0614430465ffd8a1620b178d995fe8c913871f0b376b896f
ToppCellfacs-MAT-Fat-18m-Epithelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FSD2 MAP3K13 ITGA2 TSPAN8

2.59e-06144304e4e148007c772cd163a34fb172e05184f7352a2b
ToppCellClub_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

PRSS1 KLK10 FCGBP TSPAN8

4.65e-06167304dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP ARMCX4 TSPAN8

5.23e-061723045401ac7739f95fb8681cfb4747ab6e447a3c2ae8
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP ARMCX4 TSPAN8

5.23e-06172304b3da7f488d191214d7bb74fbac189fe8c29ee6cd
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP ARMCX4 TSPAN8

5.23e-0617230474dd4a7acb2cf857fed20219e4d7dc1adfbaa398
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PLOD3 CTSB ATRNL1

5.35e-06173304807183fc23478da9451906dacd88de4e73112e0d
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PLOD3 CTSB ATRNL1

5.35e-061733042e683ec555dc0036875e0f5674dcc5e93ead205d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 FCGBP CTSB NAIP

5.86e-06177304382f0d6bbff01e84b0c7840e74ac865864e6da89
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMCX4 LTBP4 AGRN NOTCH4

7.13e-061863049c7924875f70420720149287c500b4dfa8d24673
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMCX4 LTBP4 AGRN NOTCH4

7.28e-0618730483930ef55191eff9006113feaeabb3c2fa21fd05
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMCX4 LTBP4 AGRN NOTCH4

7.28e-0618730412129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KLK10 CTSB LTBP4 NOTCH4

7.43e-0618830450b27fc12347ca16bd62333baf345c83cb422a8f
ToppCelldroplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARMCX4 LTBP4 AGRN NOTCH4

7.43e-06188304405efea75233ecf70f7d19b630230798d817b7f2
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX4 LTBP4 AGRN NOTCH4

7.59e-061893049da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCelldroplet-Skin-nan-21m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP CTSB LTBP4 AGRN

7.75e-06190304c1bfc1960a3df49c0f459454a7363804c32418ee
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

7.91e-0619130439092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

7.91e-06191304a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

7.91e-06191304a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

7.91e-061913048f6d592edc32fdb901af30501d4360512334e8c2
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX4 LTBP4 AGRN NOTCH4

7.91e-061913043307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

7.91e-06191304ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.08e-061923049093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.08e-06192304bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.08e-061923045105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.08e-06192304d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.08e-061923049ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.08e-061923040ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.24e-06193304f1199518c3626fd29bfce65070dd21a660671213
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.41e-0619430481713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.41e-06194304e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.41e-06194304627cffe2d448e74fc5df92e74e5b922a73304137
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.58e-06195304edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.58e-06195304d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.76e-06196304a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.76e-061963043e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.94e-06197304b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.94e-061973046d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.94e-06197304ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.94e-0619730437f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TENM3 LTBP4 ATRNL1

8.94e-06197304c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 FCGBP CTSB NAIP

9.12e-061983049aced8bdb56ee52866a0a9766a84336961bc4443
ToppCelldistal-mesenchymal-Adventitial_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TENM3 LTBP4 ATRNL1 TSPAN8

9.12e-06198304bfd720e2dae3b6b3dc2bf8b2096c554fd456e756
ToppCellproximal-Epithelial-Mucous-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRSS1 KLK10 FCGBP TSPAN8

9.30e-06199304baac580484124b7c36717b607adcf2cb446e631d
ToppCellproximal-Epithelial-Mucous|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRSS1 KLK10 FCGBP TSPAN8

9.30e-0619930415ba36fa6ad73d0e959e42f18d7acbc14e310dc9
ToppCellproximal-3-Epithelial-Mucous|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRSS1 KLK10 FCGBP TSPAN8

9.30e-061993043018378860de084662be0cc46fce421db3bb9ec9
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRP1 LRP3 TENM3 LTBP4

9.30e-06199304a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 FCGBP CTSB NAIP

9.49e-06200304a2548b0c77ba1616638351b111cce2fe0cacaa95
ToppCellBiopsy_Other_PF-Epithelial-KRT5-/KRT17+|Biopsy_Other_PF / Sample group, Lineage and Cell type

PRSS1 ITGA2 MUC3A AGRN

9.49e-06200304077e6b9340686de9d0f11b035a8954e1f6a1b790
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 FCGBP CTSB NAIP

9.49e-06200304e4a499b69554f78161c2c47199da77c201910e73
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LRP1 LRP3 CTSB NAIP

9.49e-06200304107a0665fb20247511a430178effd7630a619488
ToppCellBiopsy_IPF-Epithelial-Basal|Biopsy_IPF / Sample group, Lineage and Cell type

KLK10 ITGA2 LTBP4 TSPAN8

9.49e-062003045cea84581201cee7ba8141b96e65864f4fd67113
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

PRSS1 ZNF526 MAP3K13

1.06e-04137303b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCellControl-Fibroblasts-Mesothelial_FB|Control / group, cell type (main and fine annotations)

TENM3 ADCY5 ATRNL1

1.10e-04139303e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCell10x5'-bone_marrow-Myeloid_Monocytic-Cycling_mono|bone_marrow / Manually curated celltypes from each tissue

LRP1 CTSB NAIP

1.33e-04148303de35eeefad0e27a0d127e2e4bedead2bddb75152
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

KLK10 FCGBP TSPAN8

1.44e-041523031b2a39ae159e79f1fb18d6d164bd7acab5299fca
ToppCellfacs-Marrow-B-cells-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 TENM3 CTSB

1.58e-041573030966e347f8d32b13f8a3b3afba3f64637c69cdf9
ToppCellfacs-Marrow-B-cells-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 TENM3 CTSB

1.58e-041573036ebfedd91d62c6d4aa8f046657a899a279f82ba2
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 AGRN TSPAN8

1.67e-04160303bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 AGRN TSPAN8

1.67e-0416030356e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCellClub_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

KLK10 FCGBP TSPAN8

1.70e-04161303bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 AGRN TSPAN8

1.70e-0416130360f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 LTBP4 MEGF10

1.73e-04162303d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 LTBP4 MEGF10

1.73e-04162303eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 LTBP4 MEGF10

1.73e-041623035bbd7130d4dad9035e73a439dda568195c136f31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 LTBP4 MEGF10

1.73e-04162303e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCellfacs-Marrow-T_cells-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PLOD3 CTSB

1.76e-0416330330cd95d4f37bd54c1fde54960cb005db58bdd30c
ToppCellfacs-Marrow-T_cells-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PLOD3 CTSB

1.76e-04163303ab934cb986495adfc8dbe5a276577f2a8fb6ee03
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA2 ARMCX4 LTBP4

1.83e-0416530362457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

ITGA2 TENM3 MEGF10

1.83e-041653036ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX4 LTBP4 NOTCH4

1.86e-041663037a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCellBasal_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

PRSS1 ITGA2 LTBP4

1.86e-0416630323c04d1fba0c1733ccd0e4378fae2edde4fd0a7b
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX4 LTBP4 NOTCH4

1.86e-04166303bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP TSPAN8

1.86e-041663039e98e6070055bfc780becee52d77830e06b6d854
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP TSPAN8

1.89e-0416730331633899aae852873a4887e72c621474b0a51a33
ToppCellAdult-Epithelial-lung_goblet_cell-D122|Adult / Lineage, Cell type, age group and donor

KLK10 FCGBP TSPAN8

1.89e-041673036efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF526 KLK10 LTBP4

1.89e-04167303f01b96173deda0239fa482989873cf308e49d48c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF526 KLK10 LTBP4

1.89e-041673035fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP TSPAN8

1.93e-04168303b275e951ff7109e36da22fc17bd4516f9b9432c4
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP TSPAN8

1.93e-041683030757a5af953901a8faed5774ffec4755fc9c0a6e
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP TSPAN8

1.93e-04168303a0dbe2ee697e29b32aa5f8326445e067ff66c154
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

TENM3 ADCY5 ATRNL1

1.93e-04168303a086c306be430adf0632ba53e98cd8014d2de330
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 MEGF10 TSPAN8

1.96e-0416930340b557549fe08c5dc9dba359af35993d68d1640a
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP TSPAN8

1.96e-04169303db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP TSPAN8

1.96e-0416930397b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

ITGA2 TENM3 MEGF10

1.96e-04169303a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP TSPAN8

1.96e-041693031a684471dbda42e1470e5a889648666e14f25982
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|390C / Donor, Lineage, Cell class and subclass (all cells)

FCGBP CTSB NAIP

1.96e-041693032c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 LTBP4 ATRNL1

1.96e-04169303a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell10x5'-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

MEGF10 NOTCH4 GUCY2D

2.00e-0417030359cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 MEGF10 TSPAN8

2.00e-04170303fed8e982d2ce234c59d4016432ed8941df36df27
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

TENM3 ADCY5 ATRNL1

2.07e-0417230336a96714a0eb6ac438648135336c9791881ddadb
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLK10 FCGBP TSPAN8

2.07e-0417230363a91974b12c3f7f0c6bf66c30088d7fc07f5cea
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

KLK10 FCGBP TSPAN8

2.10e-04173303d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 ATRN CTSB

2.10e-0417330320f7dfe7d92a3dbec9da9a1f3185aa10cb8f0a3c
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

ITGA2 TENM3 MEGF10

2.10e-041733036fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCellwk_08-11-Mesenchymal-Fibroblast-Airway_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LRP1 TENM3 LTBP4

2.10e-04173303b23b408acc29a667cce104429afef1a6cf2720a5
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

KLK10 FCGBP TSPAN8

2.14e-041743037d2f802f493f19a068e097b2909a9000e2160266
DruguPA inhibitor

LRP1 PRSS1 CTSB

9.98e-0632303CID000001746
Drugclioquinol

LRP1 PRSS1 ITGA2 CTSB

1.48e-05114304CID000002788
DrugAC1L3UIZ

PRSS1 CTSB

1.67e-055302CID000147121
DrugVOCl3

PLOD3 ITGA2

2.51e-056302CID000024410
Drugpentaammineaquocobalt(III) tetrafluoroborate

PRSS1 ITGA2

3.51e-057302CID000412963
DrugTLCK

PRSS1 KLK10 CTSB ADCY5

5.32e-05158304CID000004427
Drugdodecyltrimethylammonium bromide

PLOD3 ITGA2

6.01e-059302CID000008152
Drugsanguinarine

ATRN ITGA2 NAIP

6.71e-0560303CID000005154
DrugCHCl

PRSS1 KLK10 CTSB

8.53e-0565303CID006432229
Drugacetone

PRSS1 KLK10 ITGA2 CTSB

1.02e-04187304CID000000180
Drugkinin 9

PRSS1 KLK10 CTSB ADCY5 GUCY2D

1.03e-04363305CID000006026
DrugPatamostat

PRSS1 CTSB

1.10e-0412302CID000065921
DrugUrapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; MCF7; HT_HG-U133A

ATRN EWSR1 PPP2R2D LTBP4

1.27e-041983045295_UP
Drugphenyl 4-guanidinobenzoate

PRSS1 CTSB

1.30e-0413302CID003015798
DrugMoxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; PC3; HT_HG-U133A

KLK10 ITGA2 CTSB LTBP4

1.30e-041993041804_UP
DrugAC1Q5JSU

PRSS1 CTSB

1.51e-0414302CID000093061
DrugONO-3307

PRSS1 CTSB

1.74e-0415302CID000127139
DrugCH3F

ITGA2 CTSB

1.99e-0416302CID000011638
Drugcamostate

PRSS1 KLK10 CTSB

2.10e-0488303CID000002536
DrugPC-PI

PRSS1 CTSB

2.53e-0418302CID000007693
DrugAC1L2Q8B

PRSS1 CTSB

3.81e-0422302CID000126377
DrugDEPX

ITGA2 ADCY5

4.55e-0424302CID000001328
DrugPEt3

ITGA2 CTSB

5.35e-0426302CID000027365
DrugParathion

KLK10 FCGBP ATRNL1 MEGF10 NOTCH4 GUCY2D

6.14e-04822306ctd:D010278
Drug5-Azachrysene

ATRN ITGA2

6.21e-0428302CID000344234
Drugmonatepil

LRP1 LRP3

6.67e-0429302CID000060810
DrugBAME

PRSS1 CTSB

8.12e-0432302CID000150869
DrugGly-pro-arg

PRSS1 ITGA2

8.12e-0432302CID000170776
DrugMr 30

PRSS1 CTSB

8.64e-0433302CID000225156
Drugcyanogen-bromide

PRSS1 ITGA2

9.17e-0434302CID000010476
Drugsalbutamol

PRSS1 ADCY5 NAIP

9.24e-04146303CID000002083
Drugcyclohexylammonium

EWSR1 CTSB NAIP

9.42e-04147303CID000007965
DrugPro-arg

PRSS1 CTSB

1.09e-0337302CID000151004
DrugAC1L1B6T

ITGA2 AGRN

1.15e-0338302CID000001308
DrugCHAPS detergent

LRP1 PRSS1 TSPAN8

1.16e-03158303CID000107670
Drugethylene oxide

ITGA2 CTSB

1.21e-0339302CID000006354
DrugNSC89634

PRSS1 CTSB

1.21e-0339302CID000070877
Drugprobucol

LRP1 LRP3 ITGA2

1.25e-03162303CID000004912
Diseasediabetes mellitus (is_implicated_in)

ITGA2 CTSB

3.72e-0429292DOID:9351 (is_implicated_in)
DiseaseMyopathy

CTSB MEGF10

3.99e-0430292C0026848
Diseaseretinal drusen

ITGA2 EGFEM1P

1.15e-0351292EFO_1001155
DiseaseMetastatic melanoma

MAP3K13 GUCY2D

1.29e-0354292C0278883
DiseaseAlzheimer's disease (implicated_via_orthology)

LRP1 NOTCH4

1.44e-0357292DOID:10652 (implicated_via_orthology)
DiseaseGlioblastoma

CTSB LTBP4

2.74e-0379292C0017636
DiseaseHodgkins lymphoma

ZNF526 FCGBP

2.95e-0382292EFO_0000183
DiseaseGiant Cell Glioblastoma

CTSB LTBP4

3.09e-0384292C0334588

Protein segments in the cluster

PeptideGeneStartEntry
QCFSCGGCLGNWEEG

NAIP

196

Q13075
QHRAGDWQCPNPGCG

EWSR1

516

Q01844
DWQCPNPGCGNQNFA

EWSR1

521

Q01844
CGDGCNGGYPAEAWN

CTSB

146

P07858
QPCFHGGTCQDWALG

AGRN

1336

O00468
GGGCPAGGNDFQWCF

PPP2R2D

6

Q66LE6
GDEQGFCGSPWPNCN

ADCY5

891

O95622
GTGDQASGWFCVCPG

ARMCX4

1501

Q5H9R4
CVCPGSQTNGGSWGG

ARMCX4

1511

Q5H9R4
WGFGCNLTCQCLNGG

MEGF10

491

Q96KG7
NGWTPEGGCGFCNQD

PLOD3

271

O60568
DPSCWFDPNNICGGG

GUCY2D

446

Q02846
WIGRQCDGTDNCGDG

LRP1

3711

Q07954
PAGWVGEQCQHCGGR

ATRN

121

O75882
GTCDNGGTWEQGQCA

MUC3A

2956

Q02505
GGTWEQGQCACLPGF

MUC3A

2961

Q02505
GPWQCNTVDECGDGS

LRP3

181

O75074
GGFLTCGPLWAQQCG

ITGA2

126

P17301
SEPDKGQAGPWGCCQ

MAP3K13

711

O43283
GWQVGGAQGCGECVS

FCGBP

2231

Q9Y6R7
AGWQVGGAQGCGECV

FCGBP

3431

Q9Y6R7
PAGWQVGGAQGCGEC

FCGBP

4631

Q9Y6R7
PGCGWCNDPSNTGRG

ATRNL1

956

Q5VV63
GEGWGSGCRIQQCPG

LTBP4

1211

Q8N2S1
EGWFSSAPCENGGQC

EGFEM1P

106

Q0D2K5
GCREPWAQESCNGGP

SSPOP

4651

A2VEC9
DLGFGGWGSAGQCQD

FSD2

131

A1L4K1
ACDAGCSGPGGNWDG

NOTCH4

1186

Q99466
VFPGNCWAFEGDQGQ

SPAG4

306

Q9NPE6
GGGCSPQSGDWGDQY

TTC13

71

Q8NBP0
QGWNGEHCTIEGCPG

TENM3

731

Q9P273
ESTAGWAQGCGDCPQ

ZNF526

266

Q8TF50
CNGQLQGVVSWGDGC

PRSS1

206

P07477
CCGLVNGAADWGNNF

TSPAN8

151

P19075
SRWGQSPGNGGGYCD

nan

56

Q8N3U1
RCAQPGDQCQVAGWG

KLK10

161

O43240