Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	TAP complex binding	HLA-A HLA-F HLA-H	4.55e-06	9	77	3	GO:0062061
GeneOntologyMolecularFunction	CD8 receptor binding	HLA-A HLA-F HLA-H	4.55e-06	9	77	3	GO:0042610
GeneOntologyMolecularFunction	TAP1 binding	HLA-A HLA-F HLA-H	6.49e-06	10	77	3	GO:0046978
GeneOntologyMolecularFunction	TAP2 binding	HLA-A HLA-F HLA-H	6.49e-06	10	77	3	GO:0046979
GeneOntologyMolecularFunction	TAP binding	HLA-A HLA-F HLA-H	6.49e-06	10	77	3	GO:0046977
GeneOntologyMolecularFunction	beta-2-microglobulin binding	HLA-A HLA-F HLA-H	1.18e-05	12	77	3	GO:0030881
GeneOntologyMolecularFunction	14-3-3 protein binding	HLA-A TBC1D22A HLA-F HLA-H	2.05e-05	42	77	4	GO:0071889
GeneOntologyMolecularFunction	natural killer cell lectin-like receptor binding	HLA-A HLA-F HLA-H	3.61e-05	17	77	3	GO:0046703
GeneOntologyMolecularFunction	T cell receptor binding	HLA-A HLA-F HLA-H	6.00e-05	20	77	3	GO:0042608
GeneOntologyMolecularFunction	MHC class I protein binding	HLA-A HLA-F HLA-H	2.52e-04	32	77	3	GO:0042288
GeneOntologyMolecularFunction	peptide antigen binding	HLA-A HLA-F HLA-H	8.94e-04	49	77	3	GO:0042605
GeneOntologyMolecularFunction	MHC protein binding	HLA-A HLA-F HLA-H	1.46e-03	58	77	3	GO:0042287
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	HLA-A HLA-F HLA-H	2.66e-06	8	76	3	GO:0002485
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	HLA-A HLA-F HLA-H	2.60e-05	16	76	3	GO:0002486
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	HLA-A HLA-F HLA-H	3.15e-05	17	76	3	GO:0002484
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	HLA-A HLA-F HLA-H	3.15e-05	17	76	3	GO:0002476
GeneOntologyBiologicalProcess	antigen processing and presentation of peptide antigen via MHC class Ib	HLA-A HLA-F HLA-H	3.77e-05	18	76	3	GO:0002428
GeneOntologyBiologicalProcess	antigen processing and presentation of exogenous peptide antigen via MHC class I	HLA-A HLA-F HLA-H	3.77e-05	18	76	3	GO:0042590
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I	HLA-A HLA-F HLA-H	8.07e-05	23	76	3	GO:0019885
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen	HLA-A HLA-F HLA-H	1.04e-04	25	76	3	GO:0002483
GeneOntologyBiologicalProcess	antigen processing and presentation via MHC class Ib	HLA-A HLA-F HLA-H	1.04e-04	25	76	3	GO:0002475
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous antigen	HLA-A HLA-F HLA-H	2.21e-04	32	76	3	GO:0019883
GeneOntologyCellularComponent	MHC class Ib protein complex	HLA-A HLA-F HLA-H	1.73e-06	7	78	3	GO:0032398
GeneOntologyCellularComponent	MHC class I protein complex	HLA-A HLA-F HLA-H	5.89e-06	10	78	3	GO:0042612
GeneOntologyCellularComponent	MHC class I peptide loading complex	HLA-A HLA-F HLA-H	1.77e-05	14	78	3	GO:0042824
GeneOntologyCellularComponent	cis-Golgi network membrane	HLA-A HLA-F HLA-H	3.27e-05	17	78	3	GO:0033106
GeneOntologyCellularComponent	Golgi medial cisterna	HLA-A HLA-F HLA-H	8.39e-05	23	78	3	GO:0005797
GeneOntologyCellularComponent	MHC protein complex	HLA-A HLA-F HLA-H	1.22e-04	26	78	3	GO:0042611
GeneOntologyCellularComponent	coated vesicle membrane	AP2M1 NECAP2 HLA-A COPA HLA-F HLA-H	1.53e-04	215	78	6	GO:0030662
GeneOntologyCellularComponent	cis-Golgi network	HLA-A GOLGA8CP HLA-F HLA-H	2.89e-04	85	78	4	GO:0005801
GeneOntologyCellularComponent	lumenal side of endoplasmic reticulum membrane	HLA-A HLA-F HLA-H	3.00e-04	35	78	3	GO:0098553
GeneOntologyCellularComponent	endoplasmic reticulum exit site	HLA-A HLA-F HLA-H	5.17e-04	42	78	3	GO:0070971
GeneOntologyCellularComponent	lumenal side of membrane	HLA-A HLA-F HLA-H	7.66e-04	48	78	3	GO:0098576
GeneOntologyCellularComponent	presynaptic endocytic zone membrane	AP2M1 DNM1L	1.21e-03	14	78	2	GO:0098835
GeneOntologyCellularComponent	Golgi cisterna	HLA-A GOLGA8CP HLA-F HLA-H	1.64e-03	135	78	4	GO:0031985
GeneOntologyCellularComponent	ER to Golgi transport vesicle membrane	HLA-A HLA-F HLA-H	1.77e-03	64	78	3	GO:0012507
GeneOntologyCellularComponent	vesicle coat	AP2M1 NECAP2 COPA	2.02e-03	67	78	3	GO:0030120
GeneOntologyCellularComponent	presynaptic endocytic zone	AP2M1 DNM1L	2.02e-03	18	78	2	GO:0098833
GeneOntologyCellularComponent	coated vesicle	AP2M1 NECAP2 HLA-A COPA HLA-F HLA-H	2.27e-03	360	78	6	GO:0030135
MousePheno	spinal cord inflammation	HLA-A HLA-F HLA-H	3.55e-06	8	57	3	MP:0030987
Domain	MHC_I_a_C	HLA-A HLA-F HLA-H	1.09e-06	6	72	3	IPR010579
Domain	MHC_I_C	HLA-A HLA-F HLA-H	1.09e-06	6	72	3	PF06623
Domain	MHC_I	HLA-A HLA-F HLA-H	6.95e-05	21	72	3	PF00129
Domain	MHC_I_a_a1/a2	HLA-A HLA-F HLA-H	6.95e-05	21	72	3	IPR001039
Domain	Haem_d1	COPA STXBP5L	2.18e-04	6	72	2	IPR011048
Domain	C1-set	HLA-A HLA-F HLA-H	1.18e-03	54	72	3	PF07654
Domain	IGc1	HLA-A HLA-F HLA-H	1.32e-03	56	72	3	SM00407
Domain	Ig_C1-set	HLA-A HLA-F HLA-H	1.46e-03	58	72	3	IPR003597
Domain	Ig/MHC_CS	HLA-A HLA-F HLA-H	1.46e-03	58	72	3	IPR003006
Domain	LY	ROS1 LRP1B	1.49e-03	15	72	2	SM00135
Domain	LDLR_classB_rpt	ROS1 LRP1B	1.49e-03	15	72	2	IPR000033
Domain	IG_MHC	HLA-A HLA-F HLA-H	1.61e-03	60	72	3	PS00290
Domain	WD40_repeat_CS	COPA STXBP5L APAF1 WDR86	3.71e-03	164	72	4	IPR019775
Domain	-	HLA-A HLA-F	3.83e-03	24	72	2	3.30.500.10
Domain	MHC_I-like_Ag-recog	HLA-A HLA-F	3.83e-03	24	72	2	IPR011161
Domain	G-protein_beta_WD-40_rep	COPA APAF1 WDR86	4.33e-03	85	72	3	IPR020472
Domain	CARD	APAF1 CASP2	5.19e-03	28	72	2	PF00619
Domain	EGF_LAM_2	NTN4 MEGF8	5.95e-03	30	72	2	PS50027
Domain	EGF_LAM_1	NTN4 MEGF8	5.95e-03	30	72	2	PS01248
Domain	CARD	APAF1 CASP2	6.34e-03	31	72	2	IPR001315
Domain	CARD	APAF1 CASP2	7.16e-03	33	72	2	PS50209
Pathway	REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY	HLA-A HLA-F HLA-H	5.75e-06	9	59	3	MM14527
Pathway	REACTOME_ER_PHAGOSOME_PATHWAY	HLA-A HLA-F HLA-H	5.43e-05	18	59	3	MM14525
Pathway	BIOCARTA_CTL_PATHWAY	HLA-A HLA-F HLA-H	7.55e-05	20	59	3	MM1374
Pathway	REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC	HLA-A HLA-F HLA-H	1.50e-04	25	59	3	MM15713
Pathway	BIOCARTA_NKCELLS_PATHWAY	HLA-A HLA-F HLA-H	1.50e-04	25	59	3	MM1465
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_MIR1_2_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES	HLA-A HLA-F	2.56e-04	6	59	2	M47468
Pathway	KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES	HLA-A HLA-F	3.57e-04	7	59	2	M47582
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES	HLA-A HLA-F	3.57e-04	7	59	2	M47530
Pubmed	Association of brain immune genes with social behavior of inbred mouse strains.	POLR3B HLA-A HLA-F HLA-H	5.12e-09	10	79	4	25895500
Pubmed	Generation of a functional cDNA encoding the LdH2 class-I molecule by using a single-LTR retroviral shuttle vector.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	1705528
Pubmed	Further studies on polymorphic expression of GM1 and GD1a in mouse liver. The presence of a third allele on the Ggm-1 locus.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2808323
Pubmed	CD8+ T-cell expansion and maintenance after recombinant adenovirus immunization rely upon cooperation between hematopoietic and nonhematopoietic antigen-presenting cells.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	21088134
Pubmed	The Tla locus: a new allele and antigenic specificity.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	69663
Pubmed	Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	12459592
Pubmed	Multiple sequences related to classical histocompatibility antigens in the mouse genome.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6264319
Pubmed	Sequence analysis of the C3H H-2K1k gene: relationship to the H-2 loci.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2714856
Pubmed	Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	10500200
Pubmed	Structural analysis of H-2Kf and H-2Kfm1 by using H-2K locus-specific sequences.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2391419
Pubmed	Embryonic mouse STO cell-derived xenografts express hepatocytic functions in the livers of nonimmunosuppressed adult rats.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	15671142
Pubmed	GENETIC BASIS OF SUSCEPTIBILITY TO VIRAL LEUKAEMOGENESIS.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	14215561
Pubmed	A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	28234229
Pubmed	Interaction of H-2Db with mutant histocompatibility gene H (KH-11) in the mouse.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6242891
Pubmed	Characterization of a severe parenchymal phenotype of experimental autoimmune encephalomyelitis in (C57BL6xB10.PL)F1 mice.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	17512611
Pubmed	Amino acid sequence of residues 1-98 of the K-2Kb murine major histocompatibility alloantigen: comparison with H-2Kb and H-2db reveals extensive localized differences.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	7018573
Pubmed	Induction of the H-2 D antigen during B cell activation.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2642506
Pubmed	A complex major histocompatibility complex D locus variant generated by an unusual recombination mechanism in mice.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	9037062
Pubmed	Nucleic acid sequences of the H-2Ks and H-2Ksm1 genes.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	1840571
Pubmed	Natural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in mice.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	20957233
Pubmed	Zooming in on the hydrophobic ridge of H-2D(b): implications for the conformational variability of bound peptides.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	11580250
Pubmed	V beta T cell repertoire of CD8+ splenocytes selected on nonpolymorphic MHC class I molecules.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	11086076
Pubmed	HLA-B*0702 transgenic, H-2KbDb double-knockout mice: phenotypical and functional characterization in response to influenza virus.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	12750360
Pubmed	Major histocompatibility complex (Mhc) class Ib gene duplications, organization and expression patterns in mouse strain C57BL/6.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	18416856
Pubmed	Convergent recombination shapes the clonotypic landscape of the naive T-cell repertoire.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	20974936
Pubmed	The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	10704462
Pubmed	West Nile virus T-cell ligand sequences shared with other flaviviruses: a multitude of variant sequences as potential altered peptide ligands.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	22573867
Pubmed	A novel H-2K splice form: predictions for other alternative H-2 splicing events.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2908875
Pubmed	Comparison of exon 5 sequences from 35 class I genes of the BALB/c mouse.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2584927
Pubmed	Transcripts of Tla genes.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	3496275
Pubmed	Comparative analysis of the CD8(+) T cell repertoires of H-2 class I wild-type/HLA-A2.1 and H-2 class I knockout/HLA-A2.1 transgenic mice.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	12147629
Pubmed	Mitotic recombination in germ cells generated two major histocompatibility complex mutant genes shown to be identical by RNA sequence analysis: Kbm9 and Kbm6.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	3458188
Pubmed	Antigens expressed by myelinating glia cells induce peripheral cross-tolerance of endogenous CD8+ T cells.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	19462379
Pubmed	Structural diversity of the classical H-2 genes: K, D, and L.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	1730883
Pubmed	DNA sequence analysis of the C3H H-2Kk and H-2Dk loci. Evolutionary relationships to H-2 genes from four other mouse strains.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	3680952
Pubmed	Thymus leukemia antigen controls intraepithelial lymphocyte function and inflammatory bowel disease.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	19004778
Pubmed	Comparison of the cloned H-2Kbm1 variant gene with the H-2Kb gene shows a cluster of seven nucleotide differences.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6300887
Pubmed	H-2-linked regulation of xenotropic murine leukemia virus expression.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6300850
Pubmed	The assembly of H2-Kb class I molecules translated in vitro requires oxidized glutathione and peptide.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	8500526
Pubmed	cDNA clone coding for part of a mouse H-2d major histocompatibility antigen.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6265910
Pubmed	Cutting edge: MHC class I-Ly49 interaction regulates neuronal function.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	18453559
Pubmed	DNA polymorphisms defined by the Tu108 probe map to the Tla region of mouse chromosome 17.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2906539
Pubmed	A single nucleotide difference at the 3' end of an intron causes differential splicing of two histocompatibility genes.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	3013627
Pubmed	DNA sequence of the mouse H-2Dd transplantation antigen gene.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	3856254
Pubmed	Structure of a gene encoding a murine thymus leukemia antigen, and organization of Tla genes in the BALB/c mouse.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	3894562
Pubmed	Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	27385590
Pubmed	Evolution of the mouse H-2K region: a hot spot of mutation associated with genes transcribed in embryos and/or germ cells.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	1348042
Pubmed	H2-K(b) and H2-D(b) regulate cerebellar long-term depression and limit motor learning.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	19346486
Pubmed	Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	18383043
Pubmed	Thymus-dependent memory phenotype CD8 T cells in naive B6.H-2Kb-/-Db-/- animals mediate an antigen-specific response against Listeria monocytogenes.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	16272298
Pubmed	Tissue-specific expression of an unusual H-2 (class I)-related gene.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6956903
Pubmed	A physical map of the Q region of B1O.P.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	8833240
Pubmed	Transplantation tolerance to a single noninherited MHC class I maternal alloantigen studied in a TCR-transgenic mouse model.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	21178009
Pubmed	Expression and function of transplantation antigens with altered or deleted cytoplasmic domains.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6604582
Pubmed	Isolation of a cDNA clone for the murine transplantation antigen H-2Kb.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6954478
Pubmed	CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	34525366
Pubmed	The H-2Kkml mutation: a single nucleotide substitution is responsible for multiple functional differences in a class I MHC molecule.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	3374494
Pubmed	Extensive deletions in the Q region of the mouse major histocompatibility complex.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	3025084
Pubmed	DNA sequence of a class I pseudogene from the Tla region of the murine MHC: recombination at a B2 alu repetitive sequence.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2543831
Pubmed	The class I major histocompatibility antigen gene activated in a line of SV40-transformed mouse cells is H-2Dd, not Qa/Tla.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2989712
Pubmed	Unique biochemical properties of a mutant MHC class I molecule, H-2Ksm1.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	1280760
Pubmed	Three cDNA clones encoding mouse transplantation antigens: homology to immunoglobulin genes.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6786753
Pubmed	Detection of a secreted form of the murine H-2 class I antigen with an antibody against its predicted carboxyl terminus.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6583704
Pubmed	Expression of H-2Dd and H-2Ld mouse major histocompatibility antigen genes in L cells after DNA-mediated gene transfer.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6571712
Pubmed	Mutation of a major histocompatibility class I locus, H-2D, leads to an increased virus burden and disease susceptibility in Theiler's virus-induced demyelinating disease.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	9222352
Pubmed	Probing for membrane domains in the endoplasmic reticulum: retention and degradation of unassembled MHC class I molecules.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	12006653
Pubmed	Changes in the coding sequence of the H-2Dk gene of metastatic cells that might account for immunogenic abnormality of its encoded antigen.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	1699529
Pubmed	Distinctive interactions at multiple site 2 subsites by allele-specific rat and mouse ly49 determine functional binding and class I MHC specificity.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	17982076
Pubmed	Identification of an H-2 Kb-presented Moloney murine leukemia virus cytotoxic T-lymphocyte epitope that displays enhanced recognition in H-2 Db mutant bm13 mice.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	7520098
Pubmed	Crystal structures of murine MHC Class I H-2 D(b) and K(b) molecules in complex with CTL epitopes from influenza A virus: implications for TCR repertoire selection and immunodominance.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	15644207
Pubmed	How a single T cell receptor recognizes both self and foreign MHC.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	17418792
Pubmed	PCR identification of class I major histocompatibility complex genes transcribed in mouse blastocyst and placenta.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	9185075
Pubmed	A potential role for shed soluble major histocompatibility class I molecules as modulators of neurite outgrowth.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	21483793
Pubmed	Phenotypical and functional characterization of the CD8+ T cell repertoire of HLA-A2.1 transgenic, H-2KbnullDbnull double knockout mice.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	10452993
Pubmed	Intestinal epithelial cells modulate CD4 T cell responses via the thymus leukemia antigen.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	21900182
Pubmed	Complex assembly, crystallization and preliminary X-ray crystallographic studies of MHC H-2Kd complexed with an HBV-core nonapeptide.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	15272181
Pubmed	Genetic control of scrapie and Creutzfeldt-Jakob disease in mice.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6408182
Pubmed	Adopting the rapamycin trapping assay to track the trafficking of murine MHC class I alleles, H-2K(b).	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	26714929
Pubmed	Partial nucleotide sequence of H-2Dd major histocompatibility antigen gene.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	3925012
Pubmed	Clusters of genes encoding mouse transplantation antigens.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6280871
Pubmed	Major histocompatibility complex class I gene controls the generation of gamma interferon-producing CD4(+) and CD8(+) T cells important for recovery from friend retrovirus-induced leukemia.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	10799615
Pubmed	Viral escape at the molecular level explained by quantitative T-cell receptor/peptide/MHC interactions and the crystal structure of a peptide/MHC complex.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	10993729
Pubmed	Nucleotide sequence of the BALB/c H-2T region gene, T3d.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	1339405
Pubmed	H-2D(b-/-) mice are susceptible to persistent infection by Theiler's virus.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	10823851
Pubmed	MHC class I Dk locus and Ly49G2+ NK cells confer H-2k resistance to murine cytomegalovirus.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	19454713
Pubmed	Single H2Kb, H2Db and double H2KbDb knockout mice: peripheral CD8+ T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	10229092
Pubmed	Comparison of nucleotide sequences of mRNAs belonging to the mouse H-2 multigene family.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6278432
Pubmed	Amino acid sequence of cyanogen bromide fragment CN-C (residues 24-98) of the mouse histocompatibility antigen H-2Dd. A comparison of the amino-terminal 100 residues of H-2Dd, Dd, Kd, and Kb reveals discrete areas of diversity.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	7295646
Pubmed	Molecular studies of murine mutant BALB/c-H-2dm2 define a deletion of several class I genes including the entire H-2Ld gene.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2879284
Pubmed	Structure and expression of a mouse major histocompatibility antigen gene, H-2Ld.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	6952248
Pubmed	The same major histocompatibility complex polymorphism involved in control of HIV influences peptide binding in the mouse H-2Ld system.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	24064213
Pubmed	Developmental Sculpting of Intracortical Circuits by MHC Class I H2-Db and H2-Kb.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	25316337
Pubmed	Amino acid sequence of the carboxyl-terminal hydrophilic region of the H-2Kb MHC alloantigen. Completion of the entire primary structure of the H-2Kb molecule.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	7306483
Pubmed	Random oligonucleotide mutagenesis: application to a large protein coding sequence of a major histocompatibility complex class I gene, H-2DP.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2903482
Pubmed	MHC Ib molecule Qa-1 presents Mycobacterium tuberculosis peptide antigens to CD8+ T cells and contributes to protection against infection.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	28475642
Pubmed	Molecular evidence that the H-2D and H-2L genes arose by duplication. Differences between the evolution of the class I genes in mice and humans.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	2351932
Pubmed	Recognition of H-2K(b) by Ly49Q suggests a role for class Ia MHC regulation of plasmacytoid dendritic cell function.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	17240452
Pubmed	Nucleotide sequence analysis of H-2Df and the spontaneous in vivo H-2Dfm2 mutation.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	1731192
Pubmed	Detailed mapping of the Rfv-1 gene that influences spontaneous recovery from Friend retrovirus-induced leukaemia.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	1627536
Pubmed	The Impact of MHC Class I Dose on Development and Maintenance of the Polyclonal Naive CD8+ T Cell Repertoire.	HLA-A HLA-F HLA-H	3.92e-07	7	79	3	32341060
Cytoband	5p15.1	H3Y2 H3Y1	1.49e-03	33	79	2	5p15.1
GeneFamily	Histocompatibility complex\|C1-set domain containing	HLA-A HLA-F HLA-H	3.06e-04	44	54	3	588
Coexpression	TABULA_MURIS_SENIS_LUNG_ENDOTHELIAL_CELL_OF_LYMPHATIC_VESSEL_AGEING	HLA-A HLA-F HLA-H	1.23e-05	16	75	3	MM3766
Coexpression	WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_DN	HLA-A HLA-F HLA-H	2.11e-05	19	75	3	MM797
Coexpression	MIKKELSEN_NPC_ICP_WITH_H3K27ME3	HLA-A HLA-F HLA-H	2.11e-05	19	75	3	MM862
Coexpression	GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_UP	UBE2R2 NECAP2 CAMK1D PLPP7 NUDT9 BIRC6	2.38e-05	200	75	6	M4021
Coexpression	GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_DN	CAMK1D KMT5C ARL13A ASB3 MRPS5 SRP68	2.38e-05	200	75	6	M8257
Coexpression	TABULA_MURIS_SENIS_HEART_VENTRICULAR_MYOCYTE_AGEING	HLA-A COPA MAEA HLA-F HLA-H	2.47e-05	120	75	5	MM3710
Coexpression	TABULA_MURIS_SENIS_BLADDER_LEUKOCYTE_AGEING	HLA-A HLA-F HLA-H	2.48e-05	20	75	3	MM3682
Coexpression	RUAN_RESPONSE_TO_TNF_UP	HLA-A HLA-F HLA-H	2.88e-05	21	75	3	MM651
Coexpression	TABULA_MURIS_SENIS_LUNG_PULMONARY_INTERSTITIAL_FIBROBLAST_AGEING	HLA-A HLA-F HLA-H	4.36e-05	24	75	3	MM3773
Coexpression	RUAN_RESPONSE_TO_TNF_TROGLITAZONE_UP	HLA-A HLA-F HLA-H	4.95e-05	25	75	3	MM672
Coexpression	TABULA_MURIS_SENIS_LUNG_NK_CELL_AGEING	HLA-A HLA-F HLA-H RPL19	6.44e-05	75	75	4	MM3759
Coexpression	TABULA_MURIS_SENIS_KIDNEY_KIDNEY_MESANGIAL_CELL_AGEING	HLA-A HLA-F HLA-H	9.55e-05	31	75	3	MM3729
Coexpression	TABULA_MURIS_SENIS_BLADDER_BLADDER_UROTHELIAL_CELL_AGEING	HIF1A HLA-A HLA-F HLA-H RPL19	1.09e-04	164	75	5	MM3680
Coexpression	MIKKELSEN_MCV6_ICP_WITH_H3K27ME3	HLA-A SACS HLA-F HLA-H	1.10e-04	86	75	4	MM834
Coexpression	TABULA_MURIS_SENIS_KIDNEY_FENESTRATED_CELL_AGEING	HLA-A HLA-F HLA-H RPL19	1.37e-04	91	75	4	MM3720
Coexpression	PAL_PRMT5_TARGETS_DN	HLA-A HLA-F HLA-H	1.38e-04	35	75	3	MM674
Coexpression	TABULA_MURIS_SENIS_LIMB_MUSCLE_SMOOTH_MUSCLE_CELL_AGEING	HLA-A GUCY1A1 HLA-F HLA-H	1.43e-04	92	75	4	MM3748
Coexpression	JACKSON_DNMT1_TARGETS_UP	HIF1A HLA-A HLA-F HLA-H	1.49e-04	93	75	4	MM1185
Coexpression	LIN_NPAS4_TARGETS_UP	PNPLA6 HLA-A HLA-F HLA-H DNAJC27	1.83e-04	183	75	5	MM767
Coexpression	TABULA_MURIS_SENIS_LUNG_CD8_POSITIVE_ALPHA_BETA_T_CELL_AGEING	HLA-A HLA-F HLA-H	1.91e-04	39	75	3	MM3758
Coexpression	TABULA_MURIS_SENIS_KIDNEY_KIDNEY_CORTEX_ARTERY_CELL_AGEING	HLA-A HLA-F HLA-H	1.91e-04	39	75	3	MM3725
Coexpression	SERVITJA_ISLET_HNF1A_TARGETS_UP	HLA-A GUCY1A1 STXBP5L HLA-F HLA-H	1.92e-04	185	75	5	MM1072
Coexpression	GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN	NTN4 HLA-A HLA-F HLA-H	2.21e-04	103	75	4	MM476
Coexpression	HOWLIN_CITED1_TARGETS_1_UP	HLA-A HLA-F HLA-H	2.22e-04	41	75	3	MM710
Coexpression	HU_GENOTOXIC_DAMAGE_4HR	HLA-A HLA-F HLA-H	2.56e-04	43	75	3	MM1204
Coexpression	TABULA_MURIS_SENIS_LUNG_TYPE_II_PNEUMOCYTE_AGEING	HLA-A HLA-F HLA-H	2.74e-04	44	75	3	MM3775
Coexpression	GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_UP	NCOR2 CAMK1D MEGF8 RAPH1 APOBEC1	2.75e-04	200	75	5	M8050
Coexpression	GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_UP	DNASE2B HIF1A NECAP2 APAF1 WDR86	2.75e-04	200	75	5	M7018
Coexpression	GSE17721_LPS_VS_CPG_16H_BMDC_DN	GUCY1A1 MSL1 RAD54L ADD3 RPL19	2.75e-04	200	75	5	M4009
Coexpression	GSE42021_CD24INT_TREG_VS_CD24INT_TCONV_THYMUS_UP	NECAP2 TBC1D22A KMT5C APOBEC1 RPL19	2.75e-04	200	75	5	M9618
Coexpression	GSE17721_PAM3CSK4_VS_CPG_24H_BMDC_DN	AP2M1 COPA SLC13A3 APOBEC1 DYNC1H1	2.75e-04	200	75	5	M3875
Coexpression	TABULA_MURIS_SENIS_HEART_AND_AORTA_ENDOCARDIAL_CELL_AGEING	HLA-A HLA-F HLA-H	3.13e-04	46	75	3	MM3712
Coexpression	BAUS_TFF2_TARGETS_UP	HLA-A HLA-F HLA-H	3.77e-04	49	75	3	MM1287
Disease	Moyamoya disease (is_implicated_in)	HLA-A GUCY1A1	5.68e-05	5	71	2	DOID:13099 (is_implicated_in)
Disease	response to serotonin-norephinephrine reuptake inhibitor	MAEA ASB3 BIRC6	9.00e-05	36	71	3	EFO_0006325
Disease	graft-versus-host disease (implicated_via_orthology)	HLA-A HLA-F	1.19e-04	7	71	2	DOID:0081267 (implicated_via_orthology)
Disease	pneumococcal meningitis	TBC1D22A ROS1	1.58e-04	8	71	2	EFO_1001114
Disease	Mental Retardation, Psychosocial	POLR3B DEAF1 CASP2 DYNC1H1	3.59e-04	139	71	4	C0025363
Disease	Profound Mental Retardation	POLR3B DEAF1 CASP2 DYNC1H1	3.59e-04	139	71	4	C0020796
Disease	Mental deficiency	POLR3B DEAF1 CASP2 DYNC1H1	3.59e-04	139	71	4	C0917816
Disease	Alpha ketoglutarate measurement	SRP68 SLC13A3	6.70e-04	16	71	2	EFO_0010457
Disease	Intellectual Disability	AP2M1 POLR3B DEAF1 SACS CASP2 DYNC1H1	7.29e-04	447	71	6	C3714756
Disease	systemising measurement	FATE1 ASB3	1.16e-03	21	71	2	EFO_0010221
Disease	S-6-hydroxywarfarin to S-warfarin ratio measurement	ASB3 ABLIM2 BIRC6	1.27e-03	88	71	3	EFO_0803332
Disease	diffusing capacity of the lung for carbon monoxide	NTN4 ABLIM2 LRP1B	1.63e-03	96	71	3	EFO_0009369
Disease	S-warfarin measurement	NCOR2 TBC1D22A LRP1B	1.67e-03	97	71	3	EFO_0803323

Protein segments in the cluster

Peptide	Gene	Start	Entry
WSADGARIMVAAKNK	APAF1	806	O14727
WVSDSARVAAMKRSG	BIRC6	3456	Q9NR09
TGNWRGMLKTSKAEE	DNM1L	586	O00429
MSRKIWRSSGKNTTN	APOBEC1	46	P41238
RNGETSPRTKITWMK	ADD3	456	Q9UEY8
MARTKQTARKATAWQ	H3Y2	1	P0DPK5
GSLDQDNRKKSSWLM	ABLIM2	451	Q6H8Q1
GTRLWSKKNMSVTFA	ARL13A	251	Q5H913
NGTRGWKEKMVTSSE	CNTN5	816	O94779
WKRGTQLEESSKARM	RAPH1	581	Q70E73
EQAMARVWRDGQKKT	RAD54L	601	Q92698
GAVVAAVMWRKKSSD	HLA-F	321	P30511
AVMWRKKSSDRNRGS	HLA-F	326	P30511
GLMDEFSKWLSKSRN	NUP107	526	P57740
SWTAADMAAQITKRK	HLA-H	156	P01893
DMAAQITKRKWEAAR	HLA-H	161	P01893
GSEKKSAWRKMRVYQ	ARHGEF19	131	Q8IW93
GRNWSAIARMVGSKT	NCOR2	631	Q9Y618
RTKQRAREWAKSMTS	PNPLA6	1031	Q8IY17
WVGNKRRKMSSKNSE	HDX	51	Q7Z353
WTDMGFNKISRAKRD	LRP1B	1926	Q9NZR2
SDQPAAASVWKRKRM	MAEA	111	Q7L5Y9
SGTQSFRRSGMWSKK	HSFX4	236	A0A1B0GTS1
AKGWRRSTGEMVAIK	HIPK4	26	Q8NE63
METNGAKIVSTRAWK	KMT5C	116	Q86Y97
RIRNSKDSWDMLGVK	DNAJC27	211	Q9NZQ0
TSRGRTMNIKSATWK	HIF1A	176	Q16665
TGSQVRWRKQKVEME	MGAM	791	O43451
GSDSTKRSRWMEKAL	KDM5D	1096	Q9BY66
MANVSKKVSWSGRDR	CLCN7	1	P51798
MARTKQTARKATAWQ	H3Y1	1	P0DPK2
TRWKRDSSGNKIMHP	NUDT9	176	Q9BW91
REGKCMWTRQFKRTG	MEGF8	2006	Q7Z7M0
ASENAIVWKIKRMAG	AP2M1	346	Q96CW1
RKSNVDFVKWSSQGM	HSPA12A	426	O43301
TLAASEGRWKSMRKS	MSL1	191	Q68DK7
SGTQSFRRSGMWSKK	HSFX3	236	A0A1B0GWH4
NRRMKWKKESNLTST	HOXC6	191	P09630
KKGRSVDVADNRGWM	ASB3	31	Q9Y575
RSWRKSEQLMNDTKS	DNASE2B	71	Q8WZ79
EAMAGRASSKDWKRS	DEAF1	241	O75398
KSIRVWDMSKRTGVQ	COPA	271	P53621
WESSRRKMGTVKTEF	COL6A5	2016	A8TX70
QGRSFSKKRMGLNRW	CCDC191	6	Q8NCU4
SWTAADMAAQITKRK	HLA-A	156	P04439
RKWQATSGQMEDTIK	LYRM1	21	O43325
DKAINTAVKSGRWVM	DYNC1H1	4081	Q14204
TFRMTGSTLKKNWNI	COL9A1	116	P20849
SASAKRVWNMTATRP	FATE1	61	Q969F0
SKRARVAQMKRTWAG	DHX37	831	Q8IY37
MAALAAAAKKVWSAR	SLC13A3	1	Q8WWT9
KTDTKGRWNTTFMRH	SACS	1901	Q9NZJ4
LKGTAAMRNTKRGSW	CASP2	371	P42575
ANTWTLMRKSRAENS	KIF28P	361	B7ZC32
VKTAQGMKRSVWSNL	MRPS5	411	P82675
SSQRSQMDTLKTKGW	SENP2	241	Q9HC62
KASNGRVKWGETMIF	TC2N	411	Q8N9U0
AMVLDRSQDFGKTWK	NTN4	141	Q9HB63
RKGTANARMPEKVTW	RPL19	81	P84098
MARENGESSSSWKKQ	CAMK1D	1	Q8IU85
RAKQAATMSEVEWRG	SRP68	286	Q9UHB9
EKSWRRKVVMNSSSA	STXBP5L	926	Q9Y2K9
TKRVKAAARQMWTSN	CCDC54	6	Q8NEL0
VLAMRQAWSKSGREK	TPST2	106	O60704
NSSISKILGSRWKSM	SOX13	451	Q9UN79
LDKSMSSWSQRGRAA	TRPM6	1751	Q9BX84
RRKSMSSWLDKQEDA	SAGE1	61	Q9NXZ1
RVGKEMDSSINKWLS	STYXL2	926	Q5VZP5
WAKKAANMSDVSDLR	ROS1	346	P08922
TGNWSLKRFKMDRQG	POLR3B	421	Q9NW08
MASDGARKQFWKRSN	TBC1D22A	1	Q8WUA7
WRKNIDALSGMEGRK	TNNI3	191	P19429
KFWKMKTTSQREGNS	ZNF221	86	Q9UK13
WKNGATRDSRGKMLS	TRMT12	371	Q53H54
NVDASVMFRKWRDSK	UBE2R2	141	Q712K3
WIRSSMAASGKRVSK	SLC14A2	541	Q15849
DRTARVWSVDKGQMS	WDR86	116	Q86TI4
GRAASWASARSMVKL	PLPP7	101	Q8NBV4
RRWDNSVKKSSRVMD	GUCY1A1	351	Q02108
SSRSKARMEWKLEQS	GOLGA8CP	191	A6NN73
SWSGRLRITAKGQMA	NECAP2	41	Q9NVZ3