Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A2 COL5A1 COL17A1

1.15e-0446413GO:0030020
GeneOntologyMolecularFunctionadenylate cyclase regulator activity

GNAS ADGRV1

1.47e-049412GO:0010854
GeneOntologyMolecularFunctioncyclase regulator activity

GNAS ADGRV1

6.16e-0418412GO:0010851
GeneOntologyBiologicalProcessregulation of neuroblast proliferation

SMARCD3 LHX5 SALL1 ZNF335

9.41e-0667414GO:1902692
GeneOntologyBiologicalProcessmesenchymal stem cell maintenance involved in metanephric nephron morphogenesis

SALL1 PAX8

1.16e-053412GO:0072309
GeneOntologyBiologicalProcessneuroblast proliferation

SMARCD3 LHX5 SALL1 ZNF335

5.35e-05104414GO:0007405
GeneOntologyBiologicalProcessmesenchymal stem cell maintenance involved in nephron morphogenesis

SALL1 PAX8

8.04e-057412GO:0072038
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle clustering

MAGI2 PICALM

1.07e-048412GO:2000809
GeneOntologyBiologicalProcessepithelial cell differentiation involved in kidney development

MAGI2 SALL1 PAX8

1.11e-0447413GO:0035850
GeneOntologyBiologicalProcessterminal button organization

SNAPIN PICALM

1.38e-049412GO:0072553
GeneOntologyBiologicalProcessregulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

SALL1 PAX8

1.38e-049412GO:0003339
GeneOntologyBiologicalProcessregulation of neural precursor cell proliferation

SMARCD3 LHX5 SALL1 ZNF335

1.47e-04135414GO:2000177
GeneOntologyBiologicalProcesspronephros development

HNF1A PAX8

1.72e-0410412GO:0048793
GeneOntologyBiologicalProcesscell differentiation involved in kidney development

MAGI2 SALL1 PAX8

1.98e-0457413GO:0061005
GeneOntologyBiologicalProcessmesenchymal to epithelial transition involved in metanephros morphogenesis

SALL1 PAX8

2.51e-0412412GO:0003337
GeneOntologyBiologicalProcessregulation of synaptic vesicle clustering

MAGI2 PICALM

2.51e-0412412GO:2000807
GeneOntologyBiologicalProcesssynaptic vesicle localization

SNAPIN MAGI2 PICALM

3.79e-0471413GO:0097479
GeneOntologyBiologicalProcessmetanephric renal vesicle morphogenesis

SALL1 PAX8

3.98e-0415412GO:0072283
GeneOntologyBiologicalProcessanatomical structure homeostasis

HNF1A PDE6A GNAS ADGRV1 PKP3

5.02e-04334415GO:0060249
GeneOntologyBiologicalProcesstissue homeostasis

HNF1A PDE6A GNAS ADGRV1 PKP3

5.02e-04334415GO:0001894
GeneOntologyBiologicalProcesspositive regulation of neural precursor cell proliferation

SMARCD3 LHX5 ZNF335

5.39e-0480413GO:2000179
GeneOntologyBiologicalProcessrenal vesicle morphogenesis

SALL1 PAX8

5.78e-0418412GO:0072077
GeneOntologyBiologicalProcessregulation of epithelial cell differentiation involved in kidney development

SALL1 PAX8

6.45e-0419412GO:2000696
GeneOntologyBiologicalProcessrenal vesicle development

SALL1 PAX8

6.45e-0419412GO:0072087
GeneOntologyBiologicalProcessmesenchymal to epithelial transition

SALL1 PAX8

7.16e-0420412GO:0060231
GeneOntologyBiologicalProcesscardiac chamber development

SMARCD3 TAB1 SALL1 PAX8

8.16e-04212414GO:0003205
GeneOntologyBiologicalProcessregulation of vesicle size

SNAPIN PICALM

8.68e-0422412GO:0097494
GeneOntologyBiologicalProcesscell differentiation involved in metanephros development

SALL1 PAX8

8.68e-0422412GO:0072202
GeneOntologyBiologicalProcessdorsal spinal cord development

DAAM2 LHX5

8.68e-0422412GO:0021516
GeneOntologyBiologicalProcesssynaptic vesicle clustering

MAGI2 PICALM

8.68e-0422412GO:0097091
GeneOntologyBiologicalProcesspositive regulation of branching involved in ureteric bud morphogenesis

SALL1 PAX8

8.68e-0422412GO:0090190
GeneOntologyCellularComponentphotoreceptor cell cilium

KIAA1549 MAGI2 HNF1A PDE6A ADGRV1

7.48e-06139415GO:0097733
GeneOntologyCellularComponent9+0 non-motile cilium

KIAA1549 MAGI2 HNF1A PDE6A ADGRV1

1.19e-05153415GO:0097731
GeneOntologyCellularComponentnon-motile cilium

KIAA1549 MAGI2 HNF1A PDE6A ADGRV1

3.92e-05196415GO:0097730
GeneOntologyCellularComponentcollagen trimer

COL4A2 COL5A1 COL17A1

6.85e-0488413GO:0005581
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A2 COL5A1

7.70e-0421412GO:0098644
MousePhenopostnatal lethality

CPEB2 COL4A2 MAGI2 LHX5 TAB1 GNAS COL17A1 TCF20 ATN1 PAX8 PICALM POLR2A

2.43e-0510843912MP:0002082
DomainCollagen

COL4A2 COL5A1 COL17A1

6.84e-0485383PF01391
DomainCollagen

COL4A2 COL5A1 COL17A1

6.84e-0485383IPR008160
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A2 COL5A1 COL17A1

1.40e-0441353MM15538
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A2 COL5A1 COL17A1

1.73e-0444353M27812
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A2 COL5A1 COL17A1

4.57e-0461353M27103
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A2 COL5A1 COL17A1

4.57e-0461353MM14637
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

COL4A2 COL5A1 SMARCD3 HNF1A ADGRV1 SALL1 ROBO3 PAX8 PKP3 ZNF335 POLR2A

4.76e-0414323511M509
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A2 COL5A1 COL17A1

5.27e-0464353M26953
PathwayWP_THYROID_STIMULATING_HORMONE_TSH_SIGNALING

GNAS PAX8 RBL2

5.76e-0466353M39684
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A2 COL5A1 COL17A1

6.02e-0467353M26999
PathwayWP_ID_SIGNALING

PAX8 RBL2

7.03e-0416352M39359
Pubmed

SPT5 stabilization of promoter-proximal RNA polymerase II.

SUPT5H POLR2A

1.36e-06241234480849
Pubmed

Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles.

HNF1A SALL1 PAX8

3.88e-062641329712641
Pubmed

Structure and function of the human transcription elongation factor DSIF.

SUPT5H POLR2A

4.06e-06341210075709
Pubmed

The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation.

SNAPIN HNF1A

4.06e-06341216330323
Pubmed

Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C.

GNAS ADGRV1

4.06e-06341224191038
Pubmed

Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA.

SUPT5H POLR2A

4.06e-06341224814348
Pubmed

Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.

SUPT5H POLR2A

4.06e-06341218197258
Pubmed

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs.

SUPT5H POLR2A

4.06e-0634129450929
Pubmed

The HNF1beta transcription factor has several domains involved in nephrogenesis and partially rescues Pax8/lim1-induced kidney malformations.

HNF1A PAX8

4.06e-06341215355349
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

HNF1A LHX5 TCF19 TCF20 PAX8 SUPT5H RBL2 POLR2A

7.24e-0687741820211142
Pubmed

Subnuclear localization of Ku protein: functional association with RNA polymerase II elongation sites.

SUPT5H POLR2A

8.12e-06441212391174
Pubmed

The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9.

SUPT5H POLR2A

8.12e-06441211575923
Pubmed

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.

HNF1A SALL1 PAX8

1.25e-053841327820600
Pubmed

Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA.

SUPT5H POLR2A

1.35e-05541211940650
Pubmed

ZWC complex-mediated SPT5 phosphorylation suppresses divergent antisense RNA transcription at active gene promoters.

SUPT5H POLR2A

2.03e-05641235325203
Pubmed

Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA.

SUPT5H POLR2A

2.03e-05641214580347
Pubmed

Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

MAGI2 ATN1

2.03e-0564129647693
Pubmed

Tace/ADAM17 is a bi-directional regulator of axon guidance that coordinates distinct Frazzled and Dcc receptor signaling outputs.

LHX5 ROBO3

2.03e-05641236476876
Pubmed

Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice.

SMARCD3 SALL1 PAX8

2.38e-054741315172686
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

PRKD2 SEC24D TAB1 GNAS ERF PICALM PKP3 POLR2A

2.44e-05103841826673895
Pubmed

Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.

COL4A2 ATXN2L GNAS TCF20 PKP3

3.70e-0532141532098917
Pubmed

Tat-SF1 protein associates with RAP30 and human SPT5 proteins.

SUPT5H POLR2A

3.78e-05841210454543
Pubmed

NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation.

SUPT5H POLR2A

3.78e-05841210199401
Pubmed

Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II.

SUPT5H POLR2A

3.78e-05841223064645
Pubmed

Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics.

SUPT5H POLR2A

3.78e-05841216327805
Pubmed

Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex.

SUPT5H POLR2A

3.78e-05841212612062
Pubmed

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

COL4A2 COL5A1 COL17A1

5.48e-056241328344315
Pubmed

Interaction network of human early embryonic transcription factors.

SMARCD3 SALL1 ERF TCF20 ATN1

5.66e-0535141538297188
Pubmed

DYRK3 phosphorylates SNAPIN to regulate axonal retrograde transport and neurotransmitter release.

SNAPIN MAGI2

6.07e-051041236585413
Pubmed

Mechanism of glycyrrhizic acid inhibition of Kaposi's sarcoma-associated herpesvirus: disruption of CTCF-cohesin-mediated RNA polymerase II pausing and sister chromatid cohesion.

SUPT5H POLR2A

6.07e-051041221880767
Pubmed

In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1.

SALL1 PAX8

6.07e-051041221345181
Pubmed

Functional proteomics mapping of a human signaling pathway.

COL4A2 SNAPIN PRKD2 SEC24D SUPT5H PDE4DIP

6.37e-0559141615231748
Pubmed

GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy.

SUPT5H POLR2A

7.41e-051141223652018
Pubmed

De novo phosphorylation of H2AX by WSTF regulates transcription-coupled homologous recombination repair.

SUPT5H POLR2A

7.41e-051141231045206
Pubmed

Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear.

SALL1 PAX8

7.41e-051141216916509
Pubmed

Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects.

SALL1 PAX8

7.41e-051141217300925
Pubmed

A census of human transcription factors: function, expression and evolution.

KIAA1549 HNF1A LHX5 SALL1 ERF PAX8 ZNF335

8.37e-0590841719274049
Pubmed

Conditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunits.

SNAPIN GNAS

8.88e-051241217110384
Pubmed

Netrin1/DCC signaling promotes neuronal migration in the dorsal spinal cord.

LHX5 ROBO3

8.88e-051241227784329
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

SMARCD3 TAB1 EFCAB6 SYNGR1

8.92e-0519941423382691
Pubmed

A genomic atlas of mouse hypothalamic development.

LHX5 ADGRV1 TCF19 ROBO3

1.00e-0420541420436479
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

SALL1 ERF TCF20 SUPT5H RBL2

1.02e-0439841535016035
Pubmed

Lhx1 and Lhx5 maintain the inhibitory-neurotransmitter status of interneurons in the dorsal spinal cord.

LHX5 PAX8

1.05e-041341217166926
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MAGI2 TCF20 NHSL2 PICALM CASKIN1 PDE4DIP MTSS2

1.21e-0496341728671696
Pubmed

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

SMARCD3 POLR2A

1.22e-04144128895581
Pubmed

Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest.

SMARCD3 RBL2

1.41e-04154129891079
Pubmed

Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences.

SUPT5H POLR2A

1.41e-041541211809800
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

KIAA1549 MAGI2 ADGRV1 CASKIN1 MTSS2

1.47e-0443041532581705
Pubmed

NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord.

LHX5 ROBO3

1.61e-041641227223328
Pubmed

BARHL2 transcription factor regulates the ipsilateral/contralateral subtype divergence in postmitotic dI1 neurons of the developing spinal cord.

LHX5 ROBO3

1.61e-041641222307612
Pubmed

Domains in the SPT5 protein that modulate its transcriptional regulatory properties.

SUPT5H POLR2A

1.61e-041641210757782
Pubmed

Developmental changes in extracellular matrix messenger RNAs in the mouse placenta during the second half of pregnancy: possible factors involved in the regulation of placental extracellular matrix expression.

COL4A2 COL5A1

1.61e-041641217881772
Pubmed

Evidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms.

SALL1 PAX8

1.61e-041641225617721
Pubmed

A novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription.

SUPT5H POLR2A

1.82e-041741210393184
Pubmed

CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA.

SUPT5H POLR2A

1.82e-041741210958691
Pubmed

DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation.

SUPT5H POLR2A

2.54e-042041211112772
Pubmed

HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.

SUPT5H POLR2A

2.54e-042041220471948
Pubmed

Prorenin receptor is critical for nephron progenitors.

SALL1 PAX8

2.54e-042041226658320
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ZDHHC5 KIAA1549 TCF20 PICALM

2.60e-0426341434702444
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ATXN2L TCF20 ATN1 PKP3 ZNF335 POLR2A

2.76e-0477441615302935
Pubmed

A Sall1-NuRD interaction regulates multipotent nephron progenitors and is required for loop of Henle formation.

SALL1 PAX8

2.81e-042141228760814
Pubmed

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

HNF1A SALL1

2.81e-042141221300955
Pubmed

A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.

SALL1 POLR2A

3.09e-042241219483677
Pubmed

Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning.

SALL1 PAX8

3.09e-042241229449451
Pubmed

Cbln1 regulates axon growth and guidance in multiple neural regions.

LHX5 ROBO3

3.09e-042241236395107
Pubmed

p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate.

COL17A1 PKP3

3.68e-042441228604778
Pubmed

Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney.

SALL1 PAX8

3.68e-042441217036046
Pubmed

Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development.

LHX5 PAX8

4.00e-042541221784065
Pubmed

Isolation and characterization of a human cDNA for mRNA 5'-capping enzyme.

SUPT5H POLR2A

4.00e-04254129512541
Pubmed

Cloning and characterization of three human cDNAs encoding mRNA (guanine-7-)-methyltransferase, an mRNA cap methylase.

SUPT5H POLR2A

4.00e-04254129790902
Pubmed

The DNA sequence of human chromosome 22.

TAB1 TCF20 EFCAB6 SYNGR1

4.27e-0430041410591208
Pubmed

ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress.

SUPT5H POLR2A

4.33e-042641234162889
Pubmed

Elongin A regulates transcription in vivo through enhanced RNA polymerase processivity.

SUPT5H POLR2A

4.33e-042641233298525
Pubmed

Characterization of a novel Lbx1 mouse loss of function strain.

ROBO3 PAX8

4.33e-042641234906895
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

GNAS ATN1 ZNF335 POLR2A PDE4DIP

4.62e-0455241510737800
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

KIAA1549 MAGI2 COL17A1

4.90e-0413041312421765
Pubmed

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.

DAAM2 MTSS2

5.03e-042841233953184
Pubmed

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.

SEC24D TAB1

5.03e-042841229653964
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

ZDHHC5 ATXN2L COL17A1 PICALM PKP3

5.14e-0456541525468996
Pubmed

Spindle Assembly Checkpoint Inhibition Can Resensitize p53-Null Stem Cells to Cancer Chemotherapy.

SMARCD3 GNAS ATN1

5.71e-0413741330862715
Pubmed

Mdm2 is required for maintenance of the nephrogenic niche.

SALL1 PAX8

5.78e-043041224440154
Pubmed

Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.

COL4A2 COL5A1

6.58e-043241223154389
Pubmed

An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells.

GNAS PICALM

6.58e-043241228388416
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SNAPIN MAGI2 PRKD2 DAAM2 SUPT5H RBL2 PDE4DIP

6.91e-04128541735914814
Pubmed

The RNA polymerase II elongation complex.

SUPT5H POLR2A

7.00e-043341212676794
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

ZDHHC5 MAGI2 ATXN2L CASKIN1

7.37e-0434741417114649
Pubmed

Joint influence of small-effect genetic variants on human longevity.

COL5A1 HNF1A

7.43e-043441220834067
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

ADGRV1 TCF20 PDE4DIP

7.72e-0415241334299191
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

COL4A2 COL5A1 COL17A1

7.87e-0415341325037231
Pubmed

Deployment of the human immunodeficiency virus type 1 protein arsenal: combating the host to enhance viral transcription and providing targets for therapeutic development.

SUPT5H POLR2A

8.33e-043641222422068
Pubmed

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.

GNAS PAX8

8.80e-043741222797727
Pubmed

A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin.

SUPT5H POLR2A

8.80e-043741218562274
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

PRKD2 TAB1 GNAS SUPT5H PICALM PKP3

9.25e-0497441628675297
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ATXN2L COL5A1 TCF20 SUPT5H POLR2A

9.85e-0465341522586326
Pubmed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.

DAAM2 GNAS ADGRV1 MTSS2

9.93e-0437641424154525
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

ATXN2L GNAS ERF RBL2 PKP3

9.98e-0465541535819319
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

ZDHHC5 DAAM2 GNAS PICALM

1.00e-0337741438117590
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

COL4A2 PAX8

1.03e-034041227068110
Pubmed

Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse.

LHX5 ROBO3

1.03e-034041231152445
Pubmed

URI Regulates KAP1 Phosphorylation and Transcriptional Repression via PP2A Phosphatase in Prostate Cancer Cells.

PKP3 POLR2A

1.13e-034241227780869
InteractionCRX interactions

SMARCD3 SALL1 ERF TCF20 ATN1 PICALM

1.17e-05254416int:CRX
CytobandEnsembl 112 genes in cytogenetic band chr22q13

TAB1 TCF20 EFCAB6 SYNGR1

2.37e-04330424chr22q13
Cytoband19q13

ERF SUPT5H

3.74e-043142219q13
Cytoband22q13.1

TAB1 SYNGR1

2.78e-038542222q13.1
CytobandEnsembl 112 genes in cytogenetic band chr16q12

SALL1 RBL2

4.05e-03103422chr16q12
CytobandEnsembl 112 genes in cytogenetic band chr20q13

GNAS PMEPA1 ZNF335

6.79e-03422423chr20q13
GeneFamilyCollagens

COL4A2 COL5A1 COL17A1

3.41e-0546253490
CoexpressionPGF_UP.V1_DN

DAAM2 PDE6A ERF PKP3 MTSS2

1.30e-05190425M2673
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL3

CPEB2 MAGI2 ADGRV1 SALL1 ERF CCDC17 MTSS2

3.23e-05574427M39056
CoexpressionJAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_DN

PDE6A PMEPA1 POLR2A

4.20e-0542423M16561
CoexpressionNABA_COLLAGENS

COL4A2 COL5A1 COL17A1

4.52e-0543423MM17060
CoexpressionNABA_COLLAGENS

COL4A2 COL5A1 COL17A1

4.84e-0544423M3005
CoexpressionAIZARANI_LIVER_C33_STELLATE_CELLS_2

COL4A2 COL5A1 GNAS ATN1

4.95e-05126424M39132
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_100

LHX5 ADGRV1 SALL1 ROBO3 PAX8

1.24e-0698415Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#2

LHX5 SALL1 PAX8

6.77e-0541413Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K2
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATXN2L ERF ATN1 PMEPA1 POLR2A MTSS2

2.13e-08186426bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATXN2L ERF ATN1 PMEPA1 POLR2A MTSS2

2.35e-08189426965e0e388251e7318f8b463816dc96ccb4658677
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D COL17A1 ROBO3 PMEPA1 PKP3

7.31e-0718042564f01494a4052186773720e10b4e7c724ff94547
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

COL4A2 COL5A1 DAAM2 PMEPA1 NHSL2

9.80e-0719142578c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCelllymphoid-T_cell-pro-T_cell|lymphoid / Lineage, cell class and subclass

COL4A2 KIAA1549 ERF MTSS2

2.22e-06984244da11182885d5f2673e85bd9c5717939b0268427
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 ADGRV1 PAX8 PDE4DIP

7.49e-06133424f303ab771482281d8793974f9f5279cee09431fe
ToppCellCOPD-Epithelial-Aberrant_Basaloid|Epithelial / Disease state, Lineage and Cell class

COL5A1 LHX5 COL17A1 PMEPA1

1.48e-051584248f66979e92f886d86cecbd26aaa0c5915c049734
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAAM2 SMARCD3 GNAS PMEPA1

1.63e-05162424c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAAM2 SMARCD3 GNAS PMEPA1

1.63e-05162424f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAAM2 SMARCD3 GNAS PMEPA1

1.63e-051624245d902bb31e691aea9749617cc88303c2448f24b8
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|(0)_Normal/No_Treatment / Stress and Cell class

MAGI2 COL5A1 SEC24D PMEPA1

2.11e-05173424c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 MAGI2 COL5A1 PAX8

2.31e-05177424da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAAM2 COL17A1 NHSL2 MTSS2

2.31e-051774248ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D ROBO3 PMEPA1 PKP3

2.41e-051794241757b9f3f4c634277a67c4f5a39d27d6b4937073
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D ROBO3 PMEPA1 PKP3

2.57e-0518242433afbb7c4352b03266501b1f4f0e751c12c7350d
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

COL4A2 COL5A1 DAAM2 PMEPA1

2.80e-051864241e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPEB2 MAGI2 HNF1A SALL1

2.80e-05186424bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

COL4A2 COL5A1 DAAM2 PMEPA1

2.80e-05186424cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 PAX8 SYNGR1

2.86e-051874249225caf66e06ebe57e90d677122acb6498607f36
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 COL5A1 DAAM2 SALL1

2.92e-05188424997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 ERF ATN1 PMEPA1

3.10e-051914248691eba35793e4e90f93d50c2145847ee51289f7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 PAX8 SYNGR1

3.23e-05193424ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 PAX8 SYNGR1

3.23e-051934240f2167eef8203a5659c8c72e4e77646003d64797
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 DAAM2 SEC24D

3.37e-05195424783bfa8110161cbd6def50ce849cae676c39c458
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 DAAM2 SEC24D

3.37e-05195424cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 COL5A1 DAAM2 SALL1

3.43e-051964242ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCelldroplet-Heart-HEART|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DAAM2 SMARCD3 GNAS

3.50e-051974249654472f1d4c9a6caadf1ff61a84902d171e9eb4
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

COL5A1 ADGRV1 ERF PMEPA1

3.50e-051974249d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

COL4A2 COL5A1 ERF PMEPA1

3.50e-051974241bb8f9535a9ab6c7a444bcbe346fcc0a13b09bdf
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

COL5A1 ADGRV1 ERF PMEPA1

3.50e-0519742461749ccafeb938c310cff1de5ff924a1c794325a
ToppCellCD8+_Memory_T_cell-CV-3|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

SMARCD3 TCF19 PMEPA1 SYNGR1

3.50e-051974249fe3d53346a95c1bbb0fc6a2f2e974889873424b
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma|TCGA-Pancreas / Sample_Type by Project: Shred V9

ZDHHC5 COL17A1 PMEPA1 PICALM

3.50e-05197424d8355f07a53e771052f9ab6b38814365dfe8d9ae
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

COL4A2 MAGI2 COL5A1 NHSL2

3.50e-05197424fb847f2277609c31fffcdf49517243ce0684facf
ToppCelldroplet-Heart-HEART-1m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DAAM2 SMARCD3 GNAS

3.50e-051974241ec3c05a5d4163df2cf0d168e28a3f1d35364da2
ToppCellCV-Moderate-3|CV / Virus stimulation, Condition and Cluster

SMARCD3 TCF19 PMEPA1 SYNGR1

3.50e-051974247031286e300eaccf73b927939f8de3a9d2d5fc74
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 COL5A1 DAAM2 SALL1

3.57e-0519842438b37daf41d84e5bf913eb3f72963418b7c0aac6
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

COL4A2 KIAA1549 SALL1 POLR2A

3.64e-05199424358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 PMEPA1 PAX8 SYNGR1

3.72e-05200424ae91dc047dc80560ba298d8d21a772154fa2775d
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 DAAM2 ZNF335

3.03e-041394234efab4421e3448880a1dcf981f6a65131b038010
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 DAAM2 ZNF335

3.03e-0413942339f3c28f89c37bb8cc049c56d2948ea906fb3d86
ToppCell10x5'-bone_marrow-Lymphocytic_B-GC_B_(I)|bone_marrow / Manually curated celltypes from each tissue

KIAA1549 COL5A1 TCF19

4.33e-04157423d4da4057917dda066da0f2aac2621fdaf1fb943b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 PAX8 SUPT5H

4.41e-041584231cefb82b9bf79c687a119be568cfc15b14c6e040
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

COL5A1 ROBO3 NHSL2

4.49e-041594233f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

COL5A1 SEC24D PMEPA1

4.58e-04160423ab769516f9f7798d1390ef215caf22a2d3d53e63
ToppCelllymphoid-T_cell-pro-T_cell|T_cell / Lineage, cell class and subclass

COL4A2 KIAA1549 ERF

4.58e-0416042366fe86d2f37983761141e5bb3de127f0b4bb0951
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 DAAM2 SMARCD3

4.75e-04162423bfaeff19bb56598fdc8c82be71d51787cf13928f
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL5A1 PMEPA1

4.75e-0416242357d627259d27f39885bf416d74bcb6656db6e27b
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

COL5A1 ROBO3 PKP3

4.92e-041644232ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-1|TCGA-Ovary / Sample_Type by Project: Shred V9

KIAA1549 ADGRV1 SALL1

5.01e-041654232ca1154a8692af311d99a4d3aa2f2ac3d23a4310
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 ROBO3 PKP3

5.27e-04168423e8878ec68b21c8d5694d7209b816d2f869673164
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 ROBO3 PKP3

5.27e-04168423a007758c219d3d5db2b5529f29af63be0d408304
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 COL5A1 DAAM2

5.37e-04169423c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL5A1 TCF19 PMEPA1

5.37e-04169423335619507857383c3b0b507cdf05d786ed59e585
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 ERF POLR2A

5.37e-0416942312bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 DAAM2 SEC24D

5.37e-04169423a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIAA1549 TCF19 PMEPA1

5.55e-041714231efce222989460bb59bd9fa955e7d9a60c73994c
ToppCelldroplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC24D ROBO3 PKP3

5.55e-041714232dfed6e9ac89adb2501a1a5e1ca895f49190562d
ToppCelldroplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC24D ROBO3 PKP3

5.55e-041714232aaae0229c3a13d0275a03a3d576db650c2bf2c0
ToppCellAT1-AT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL5A1 PMEPA1

5.55e-041714230b9912f07393aca889db72b40da08e0bc9bc1e8c
ToppCelldroplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D ROBO3 PKP3

5.74e-041734238fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCelldroplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D ROBO3 PKP3

5.74e-04173423f663571aaae2365660a8b526c355f4bd1a124a74
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1549 POLR2A PDE4DIP

5.84e-04174423f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

COL4A2 COL5A1 ATN1

5.84e-04174423fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL5A1 DAAM2 PMEPA1

5.94e-041754231799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 SEC24D

5.94e-04175423f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 SEC24D

5.94e-04175423910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D ROBO3 PMEPA1

6.04e-04176423d4075796c38b775fe721abb47426e662a0d415e3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 COL5A1 PAX8

6.04e-04176423327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 NHSL2

6.04e-041764239bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4|TCGA-Lung / Sample_Type by Project: Shred V9

COL5A1 SEC24D PICALM

6.04e-041764230923b01137d6f9956ca815b41102c81e82624065
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 NHSL2

6.04e-041764233f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 DAAM2 PMEPA1

6.14e-04177423a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAGI2 COL5A1 COL17A1

6.14e-0417742330f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 DAAM2 PMEPA1

6.14e-041774233645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SMARCD3 PDE6A MTSS2

6.14e-04177423928118b0ed120ec01c7d753ce523ab609ac24e5f
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAAM2 SMARCD3 LHX5

6.14e-04177423dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 COL5A1 PAX8

6.24e-04178423c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAAM2 SMARCD3 LHX5

6.24e-04178423416f85e51f45ec7949451fd47611a84e33e87245
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SALL1 EFCAB6 PAX8

6.24e-041784238b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 DAAM2

6.24e-04178423d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SALL1 EFCAB6 PAX8

6.24e-0417842358857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SALL1 EFCAB6 PAX8

6.24e-04178423b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 DAAM2

6.24e-0417842378a0c6340001a77f5b2d890b6263f574af2e72da
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D ROBO3 PMEPA1

6.34e-0417942387a69f9f83b8f0c028a4874acb238f2e079bf51f
ToppCelldroplet-Marrow-nan-3m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D ROBO3 PMEPA1

6.34e-04179423dcaf2191134a586d50ebaf67dcf5b815b54a722b
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

MAGI2 COL5A1 NHSL2

6.34e-04179423e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCelldroplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1549 SEC24D ROBO3

6.34e-04179423d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 MAGI2 COL5A1

6.45e-04180423f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D ROBO3 PMEPA1

6.45e-04180423bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D ROBO3 PMEPA1

6.45e-0418042382965ed1b72a1873c24dd4553d39681596057316
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 COL5A1 DAAM2

6.45e-0418042301f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB2 ADGRV1 PDE4DIP

6.45e-041804239e09b3dfe344b5d50520711513d389865d73a861
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D ROBO3 PMEPA1

6.45e-04180423df60970520fba2ac0639faa54096766d07418ca4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 ADGRV1 PAX8

6.55e-041814239d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAAM2 SMARCD3 CASKIN1

6.55e-04181423429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL5A1 PAX8

6.55e-041814236a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 MAGI2 PAX8

6.55e-04181423071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAAM2 COL17A1 NHSL2

6.55e-041814234df7972f88117108698efd06b124b232f8588981
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAAM2 SMARCD3 CASKIN1

6.55e-04181423395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|(2)_5-FU / Stress and Cell class

COL5A1 PMEPA1 PDE4DIP

6.55e-0418142356ae86072858c156681507aecd1bc6cb0a3372d2
DrugEthopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; HL60; HT_HG-U133A

MAGI2 COL17A1 ROBO3 ATN1 PMEPA1 PDE4DIP

1.28e-061954163038_UP
DrugProglumide [6620-60-6]; Down 200; 12uM; PC3; HT_HG-U133A

ATXN2L SEC24D ATN1 PICALM PKP3 PDE4DIP

1.36e-061974164337_DN
DrugAmiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; PC3; HT_HG-U133A

SMARCD3 ATN1 PAX8 PKP3 PDE4DIP MTSS2

1.40e-061984163990_DN
DrugAzathymine, 6 [932-53-6]; Down 200; 31.4uM; PC3; HT_HG-U133A

COL4A2 SEC24D TAB1 ATN1 PKP3 MTSS2

1.40e-061984163987_DN
Druggenistein; Up 200; 10uM; MCF7; HG-U133A

COL4A2 DAAM2 SEC24D GNAS SYNGR1 PDE4DIP

1.44e-06199416638_UP
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; PC3; HT_HG-U133A

SMARCD3 SEC24D ATN1 PAX8 PDE4DIP MTSS2

1.44e-061994164016_DN
DrugSulfameter [651-06-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A

TAB1 ATN1 ZNF335 SYNGR1 PDE4DIP MTSS2

1.44e-061994166212_UP
DrugC2SI

ATXN2L SALL1 TCF19

6.05e-0620413CID006327160
DrugGTX8

ATN1 RBL2 POLR2A

1.92e-0529413CID000104985
Drugtroglitazone; Down 200; 10uM; PC3; HT_HG-U133A

ATXN2L TAB1 ATN1 SYNGR1 PDE4DIP

2.14e-051884154456_DN
DrugGW8510; Up 200; 10uM; MCF7; HT_HG-U133A

COL5A1 GNAS ROBO3 PKP3 SYNGR1

2.37e-051924157062_UP
DrugFludrocortisone acetate [514-36-3]; Down 200; 9.4uM; PC3; HT_HG-U133A

COL4A2 ATXN2L ATN1 PICALM PKP3

2.37e-051924154342_DN
DrugICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A

HNF1A GNAS PAX8 PICALM PKP3

2.43e-051934157490_UP
DrugPF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A

ATXN2L GNAS SALL1 ATN1 PDE4DIP

2.43e-051934155922_UP
Drug2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A

ATXN2L SALL1 ATN1 PKP3 PDE4DIP

2.43e-051934152682_UP
DrugPromethazine hydrochloride [58-33-3]; Up 200; 12.4uM; PC3; HT_HG-U133A

ATXN2L COL5A1 PAX8 PDE4DIP MTSS2

2.43e-051934156717_UP
DrugFusaric acid [536-69-6]; Up 200; 22.4uM; MCF7; HT_HG-U133A

DAAM2 COL17A1 SUPT5H POLR2A MTSS2

2.49e-051944153245_UP
DrugCarbarsone [121-59-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A

ATXN2L SEC24D COL17A1 ATN1 PDE4DIP

2.49e-051944154110_UP
DrugMetformin hydrochloride [1115-70-4]; Down 200; 24.2uM; HL60; HT_HG-U133A

ATXN2L TAB1 GNAS PAX8 POLR2A

2.49e-051944151858_DN
DrugPrednicarbate [73771-04-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A

ATXN2L COL5A1 SALL1 PAX8 MTSS2

2.55e-051954153542_UP
DrugMoxalactam disodium salt [64953-12-4]; Up 200; 7uM; HL60; HT_HG-U133A

COL5A1 EFCAB6 PMEPA1 PAX8 PKP3

2.55e-051954153028_UP
DrugSpiramycin [8025-81-8]; Down 200; 4.8uM; MCF7; HT_HG-U133A

PRKD2 SMARCD3 SEC24D SYNGR1 PDE4DIP

2.62e-051964153844_DN
DrugPiracetam [7491-74-9]; Down 200; 28.2uM; MCF7; HT_HG-U133A

PRKD2 COL5A1 ZNF335 SYNGR1 PDE4DIP

2.62e-051964155462_DN
DrugGlafenine hydrochloride [65513-72-6]; Down 200; 9.8uM; PC3; HT_HG-U133A

PRKD2 COL5A1 SEC24D PICALM PDE4DIP

2.62e-051964157257_DN
DrugPhenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A

COL5A1 SMARCD3 SEC24D GNAS PDE4DIP

2.68e-051974156105_DN
DrugTobramycin [32986-56-4]; Down 200; 8.6uM; PC3; HT_HG-U133A

ROBO3 ATN1 PKP3 PDE4DIP MTSS2

2.75e-051984154081_DN
DrugPentetic acid [67-43-6]; Down 200; 10.2uM; PC3; HT_HG-U133A

COL5A1 SMARCD3 ATN1 SUPT5H PDE4DIP

2.75e-051984154669_DN
Drugarachidonyl trifluoromethyl ketone; Up 200; 10uM; MCF7; HG-U133A

ATXN2L DAAM2 SMARCD3 GNAS ERF

2.75e-05198415594_UP
DrugKanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A

MAGI2 HNF1A COL17A1 ATN1 PDE4DIP

2.81e-051994155686_UP
DrugSolanine alpha [20562-02-1]; Down 200; 4.6uM; PC3; HT_HG-U133A

ATXN2L COL5A1 TAB1 PAX8 MTSS2

2.81e-051994154087_DN
DrugBumetanide [28395-03-1]; Up 200; 11uM; HL60; HT_HG-U133A

COL4A2 ATXN2L COL17A1 PAX8 MTSS2

2.81e-051994152409_UP
DrugDNA-PK Inhibitor III; Down 200; 1uM; PC3; HT_HG-U133A

ATXN2L HNF1A ATN1 PKP3 PDE4DIP

2.81e-051994157548_DN
DrugSC45647

GNAS TCF19 POLR2A

4.04e-0537413CID005289342
DrugSp 1 (pharmaceutical)

COL5A1 HNF1A PDE6A TCF20 PMEPA1 RBL2 POLR2A

4.98e-05548417CID000099040
Drugpanobinostat

KIAA1549 MAGI2 SEC24D GNAS ADGRV1 PMEPA1 NHSL2 POLR2A SYNGR1 PDE4DIP

9.66e-0513334110ctd:C496932
DrugSuloctidil [54063-56-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A

SEC24D GNAS PDE4DIP MTSS2

2.45e-041704145021_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA

PRKD2 ATXN2L SEC24D PDE4DIP

2.74e-041754141006_UP
DrugAC1O43PA

SNAPIN SALL1

2.84e-0414412CID006323294
Drugresveratrol; Up 200; 10uM; MCF7; HT_HG-U133A_EA

GNAS ROBO3 PAX8 PDE4DIP

3.38e-04185414841_UP
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A

SEC24D GNAS ATN1 PDE4DIP

3.45e-041864142684_UP
DrugCloperastine hydrochloride [14984-68-0]; Up 200; 11uM; PC3; HT_HG-U133A

HNF1A ATN1 PMEPA1 PDE4DIP

3.45e-041864144271_UP
DrugMetixene hydrochloride [1553-34-0]; Up 200; 11.6uM; PC3; HT_HG-U133A

DAAM2 PMEPA1 PAX8 PDE4DIP

3.45e-041864146672_UP
Drugthioridazine hydrochloride; Up 200; 10uM; PC3; HT_HG-U133A

SEC24D ATN1 PMEPA1 PDE4DIP

3.59e-041884145921_UP
DrugBepridil hydrochloride [74764-40-2]; Up 200; 10uM; MCF7; HT_HG-U133A

MAGI2 SALL1 PAX8 PDE4DIP

3.74e-041904145674_UP
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A

ATXN2L ATN1 PAX8 PKP3

3.74e-041904144274_UP
DrugPropantheline bromide [50-34-0]; Down 200; 9uM; MCF7; HT_HG-U133A

ERF PICALM PKP3 PDE4DIP

3.74e-041904143352_DN
Drug11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A

ATXN2L SMARCD3 TAB1 ATN1

3.81e-041914147538_UP
Drugcyclosporine A; Up 200; 1uM; MCF7; HG-U133A

SEC24D PAX8 SYNGR1 PDE4DIP

3.81e-04191414261_UP
DrugAld1.1-H_000455; Up 200; 10uM; MCF7; HT_HG-U133A

ATXN2L COL5A1 DAAM2 PKP3

3.81e-041914147542_UP
Drug0317956-0000 [391210-11-0]; Down 200; 1uM; PC3; HT_HG-U133A

COL4A2 ATN1 PICALM PKP3

3.89e-041924144334_DN
DrugLY 294002; Down 200; 10uM; HL60; HT_HG-U133A

COL4A2 ATXN2L GNAS ROBO3

3.89e-041924142699_DN
DrugEquilin [474-86-2]; Up 200; 15uM; MCF7; HT_HG-U133A

ATXN2L COL5A1 DAAM2 SEC24D

3.89e-041924145620_UP
DrugBacampicillin hydrochloride [37661-08-8]; Up 200; 8uM; HL60; HT_HG-U133A

SEC24D TAB1 GNAS PDE4DIP

3.89e-041924141337_UP
DrugMeclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; PC3; HT_HG-U133A

ATN1 PAX8 PKP3 POLR2A

3.89e-041924144268_UP
DrugIsoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; PC3; HT_HG-U133A

PRKD2 ATXN2L ATN1 PKP3

3.97e-041934144226_DN
DrugCefalonium [5575-21-3]; Down 200; 8.8uM; PC3; HT_HG-U133A

SEC24D ATN1 PDE4DIP MTSS2

3.97e-041934144245_DN
DrugAcetaminophen [103-90-2]; Down 200; 26.4uM; MCF7; HT_HG-U133A

COL5A1 TAB1 SUPT5H PDE4DIP

4.04e-041944145384_DN
DrugCinchonine [118-10-5]; Down 200; 13.6uM; PC3; HT_HG-U133A

SMARCD3 ATN1 PAX8 PKP3

4.04e-041944143988_DN
Drug17-AAG; Up 200; 1uM; SKMEL5; HG-U133A

PDE6A PAX8 PICALM PDE4DIP

4.04e-04194414505_UP
DrugClobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A

PAX8 POLR2A PDE4DIP MTSS2

4.04e-041944146835_UP
DrugZalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A

ATXN2L COL5A1 SEC24D PDE4DIP

4.04e-041944147352_UP
DrugVincamine [1617-90-9]; Down 200; 11.2uM; PC3; HT_HG-U133A

GNAS ATN1 PICALM PKP3

4.04e-041944144341_DN
DrugSkimmianine [83-95-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A

TAB1 GNAS RBL2 SYNGR1

4.04e-041944146066_DN
DrugCarbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A

COL4A2 PDE6A EFCAB6 PAX8

4.04e-041944145610_UP
Drug(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; MCF7; HT_HG-U133A

ATXN2L COL5A1 SMARCD3 ATN1

4.04e-041944143384_DN
DrugLY 294002; Up 200; 10uM; HL60; HT_HG-U133A

TAB1 GNAS PKP3 PDE4DIP

4.04e-041944142687_UP
DrugS(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A

MAGI2 TAB1 PAX8 PDE4DIP

4.04e-041944145695_UP
DrugPalmatine chloride [3486-67-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A

PRKD2 PICALM SYNGR1 PDE4DIP

4.12e-041954144957_DN
Druggenistein; Up 200; 10uM; MCF7; HT_HG-U133A_EA

ATXN2L TAB1 PKP3 SYNGR1

4.12e-041954141015_UP
DrugPNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A

TAB1 GNAS ERF PKP3

4.12e-041954143735_DN
DrugF0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A

COL5A1 TAB1 ATN1 PDE4DIP

4.12e-041954146424_DN
DrugGallamine triethiodide [65-29-2]; Up 200; 4.4uM; MCF7; HT_HG-U133A

DAAM2 SEC24D ATN1 PDE4DIP

4.12e-041954146215_UP
Drugmonastrol; Up 200; 100uM; MCF7; HG-U133A

SEC24D GNAS ERF PAX8

4.12e-04195414596_UP
DrugTyloxapol [25301-02-4]; Down 200; 4uM; PC3; HT_HG-U133A

SMARCD3 ATN1 PKP3 SYNGR1

4.12e-041954144611_DN
DrugNitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A

COL5A1 SMARCD3 SEC24D MTSS2

4.12e-041954144705_UP
DrugSulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A

TAB1 ATN1 PKP3 PDE4DIP

4.12e-041954144326_DN
DrugNialamide [51-12-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A

ATXN2L SMARCD3 ATN1 SYNGR1

4.12e-041954143871_DN
DrugRapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A

PRKD2 SEC24D ZNF335 SYNGR1

4.12e-041954141162_DN
DrugICI182,780; Down 200; 1uM; PC3; HT_HG-U133A

SEC24D COL17A1 ATN1 SYNGR1

4.12e-041954145969_DN
DrugFluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A

ATXN2L COL17A1 ATN1 MTSS2

4.20e-041964144114_UP
DrugCephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A

ATXN2L SMARCD3 SEC24D SYNGR1

4.20e-041964142628_UP
Drug5162773; Down 200; 7uM; MCF7; HT_HG-U133A_EA

COL5A1 ATN1 SYNGR1 MTSS2

4.20e-04196414892_DN
DrugGraveoline [485-61-0]; Down 200; 14.4uM; PC3; HT_HG-U133A

ATXN2L SEC24D ERF ATN1

4.20e-041964143716_DN
Drug6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; MCF7; HT_HG-U133A

ATXN2L HNF1A TAB1 PDE4DIP

4.20e-041964147346_UP
DrugIoxaglic acid [59017-64-0]; Down 200; 3.2uM; MCF7; HT_HG-U133A

ATXN2L COL5A1 TAB1 PAX8

4.20e-041964147470_DN
Drugalpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA

ATN1 PKP3 SYNGR1 PDE4DIP

4.20e-04196414990_UP
DrugPempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A

COL4A2 PDE6A GNAS ATN1

4.20e-041964146027_UP
Drugrosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A

GNAS SYNGR1 PDE4DIP MTSS2

4.20e-041964145593_UP
DrugAtracurium besylate [64228-81-5]; Down 200; 3.2uM; MCF7; HT_HG-U133A

ATXN2L COL5A1 ZNF335 PDE4DIP

4.20e-041964147477_DN
DrugEthamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A

HNF1A TAB1 SYNGR1 MTSS2

4.20e-041964147335_UP
DrugHomatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A

GNAS ATN1 PKP3 PDE4DIP

4.20e-041964141684_DN
DrugMafenide hydrochloride [138-37-4]; Down 200; 18uM; MCF7; HT_HG-U133A

PRKD2 ATN1 PICALM PDE4DIP

4.20e-041964145499_DN
DrugLY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

PRKD2 SEC24D RBL2 PKP3

4.20e-041964141054_DN
DrugHydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A

DAAM2 SMARCD3 ATN1 MTSS2

4.29e-041974142889_UP
Drugestradiol, USP; Down 200; 0.1uM; HL60; HT_HG-U133A

PRKD2 ATXN2L SEC24D TAB1

4.29e-041974142668_DN
DrugCP-319743 [172078-87-4]; Down 200; 10uM; MCF7; HT_HG-U133A

ATXN2L ATN1 POLR2A PDE4DIP

4.29e-041974147486_DN
DrugPropofol [2078-54-8]; Up 200; 22.4uM; HL60; HT_HG-U133A

COL5A1 PMEPA1 PKP3 PDE4DIP

4.29e-041974143048_UP
DrugLomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

ATXN2L TAB1 ATN1 PDE4DIP

4.29e-041974143620_DN
DrugPNU-0251126 [267429-19-6]; Down 200; 1uM; MCF7; HT_HG-U133A

SEC24D ATN1 PICALM PDE4DIP

4.29e-041974144714_DN
Drugrotenone; Down 200; 1uM; PC3; HT_HG-U133A

ATN1 PKP3 SYNGR1 PDE4DIP

4.29e-041974145948_DN
DiseaseGlobal developmental delay

TCF20 ATN1 ZNF335 POLR2A

3.51e-05133414C0557874
Diseaseblood urea nitrogen measurement

COL4A2 HNF1A GNAS ADGRV1 PMEPA1 PAX8

3.57e-05452416EFO_0004741
DiseaseIschemic stroke, fibrinogen measurement

ATXN2L HNF1A PMEPA1

6.21e-0555413EFO_0004623, HP_0002140
Diseasefibrinogen measurement, factor VII measurement

ATXN2L HNF1A PMEPA1

7.29e-0558413EFO_0004619, EFO_0004623
Diseaseserum urea measurement

COL4A2 HNF1A GNAS PAX8

1.55e-04195414EFO_0009795
DiseaseGeneralized hypotonia

ATN1 POLR2A

1.96e-0415412C1858120
Diseasecystatin C measurement

HNF1A GNAS ADGRV1 SALL1 PAX8

2.29e-04402415EFO_0004617
DiseaseFamilial Progressive Myoclonic Epilepsy

CERS1 ATN1

2.53e-0417412C0751777
DiseaseAtypical Inclusion-Body Disease

CERS1 ATN1

2.53e-0417412C0751776
DiseaseMyoclonic Epilepsies, Progressive

CERS1 ATN1

2.53e-0417412C0751778
DiseaseBiotin-Responsive Encephalopathy

CERS1 ATN1

2.53e-0417412C0751780
DiseaseMay-White Syndrome

CERS1 ATN1

2.53e-0417412C0751782
DiseaseDentatorubral-Pallidoluysian Atrophy

CERS1 ATN1

2.53e-0417412C0751781
DiseaseFeeding difficulties

ATN1 POLR2A

2.84e-0418412C0232466
DiseaseAction Myoclonus-Renal Failure Syndrome

CERS1 ATN1

2.84e-0418412C0751779
Diseasetyrosine measurement

COL5A1 HNF1A ADGRV1

4.11e-04104413EFO_0005058
DiseaseN-glycan measurement

HNF1A TAB1

4.28e-0422412EFO_0004999
Diseaserenal system measurement, blood urea nitrogen measurement

GNAS PAX8

4.28e-0422412EFO_0004741, EFO_0004742
DiseaseIGF-1 measurement

HNF1A GNAS SALL1 PMEPA1 PAX8

5.56e-04488415EFO_0004627
Diseasecognitive function measurement

COL4A2 ATXN2L COL5A1 TAB1 TCF20 RBL2 ZNF335 POLR2A

6.94e-041434418EFO_0008354
Diseasehyperuricemia

PRKD2 GNAS

9.68e-0433412EFO_0009104
DiseaseC-reactive protein measurement, high density lipoprotein cholesterol measurement

HNF1A PMEPA1

1.03e-0334412EFO_0004458, EFO_0004612
DiseaseSclerocystic Ovaries

PRKD2 TAB1 GNAS

1.06e-03144413C1136382
DiseasePolycystic Ovary Syndrome

PRKD2 TAB1 GNAS

1.06e-03144413C0032460
DiseaseDevelopmental delay (disorder)

TCF20 ZNF335

1.22e-0337412C0424605

Protein segments in the cluster

PeptideGeneStartEntry
SSTMYVSGPPGPPGP

COL17A1

986

Q9UMD9
PTLSPMYPSGGGGPS

ERF

281

P50548
LPTSDMLGPAPYDPG

CCDC17

381

Q96LX7
TMAEGGVPSPGPGAY

C17orf114

41

A0A1B0GUV1
AMSPSLGSLRPYPPG

ATN1

531

P54259
GPSTAFFTPGSGMPP

ADGRV1

6176

Q8WXG9
PGLPGMPGRSVSIGY

COL4A2

1476

P08572
GETSVPPPPAVGRMY

ATXN2L

431

Q8WWM7
LSGREMVGPTLPGYP

PAX8

361

Q06710
YEDYGMTPPTGPLPR

KIAA1549

1751

Q9HCM3
NDSPSDGGTPGRMPP

RBL2

686

Q08999
GMGLPLPQDPYPSSD

DAAM2

576

Q86T65
GDGPPGPSSPMSRSQ

CASKIN1

711

Q8WXD9
SMPTDGQLDGTYPPP

MAGI2

571

Q86UL8
PTVPDSPGYMGPTRA

MTSS2

596

Q765P7
MGEVPPYSGPRTPDG

PDE6A

296

P16499
MATAPSYPAGLPGSP

PRKD2

1

Q9BZL6
LAMDTYSGPPPGPGP

HNF1A

281

P20823
GEVFSGGPSPPFPMS

LHX5

366

Q9H2C1
GGPSPPFPMSGTSGY

LHX5

371

Q9H2C1
SGGRMEGPPPTYSEV

PMEPA1

221

Q969W9
MPPPSPDSENGFYPG

CPEB2

1

Q7Z5Q1
AGFEDPPMRGPETTP

EFCAB6

696

Q5THR3
PAAGPTGPEPMPSYA

CERS1

6

P27544
YDPTSSPSEIGPGMP

COL5A1

421

P20908
PTSTGIPYGMSIPPE

SALL1

521

Q9NSC2
RAMLDSGIYPPGSPG

SNAPIN

121

O95295
GYPLGEMSQPTPSPA

TAB1

366

Q15750
SPGRPPGLMSPSSGY

NHSL2

701

Q5HYW2
GSRGGYSPPPEETMP

GNAS

211

Q5JWF2
PGSPYMGSPAVRPGL

SMARCD3

46

Q6STE5
SPVGYSPMTPGAPSP

SUPT5H

946

O00267
SPMTPGAPSPGGYNP

SUPT5H

951

O00267
SYGSGMAPPSQGPPG

SEC24D

131

O94855
PEGPPGTSPSEFYFM

TCF19

106

Q9Y242
PATTPTGMIGYGIPP

PICALM

601

Q13492
AGYGGAQPTPPMPTR

PKP3

146

Q9Y446
ASSRPPMGLGPAPYS

ROBO3

946

Q96MS0
GPSSPYIPSPGGAMS

POLR2A

1576

P24928
EPTGPDPAGMGGTYQ

SYNGR1

201

O43759
SGPPGMSSQKRYGPP

TCF20

1201

Q9UGU0
SPEPGPTAPYLGRSM

ZDHHC5

621

Q9C0B5
APPMEEGTSAPGTPY

ZNF335

886

Q9H4Z2
PSFSPPSPMGGDSNR

PDE4DIP

986

Q5VU43