Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin-like protein-specific endopeptidase activity

SENP6 SENP7

3.15e-055362GO:0070137
GeneOntologyMolecularFunctionSUMO-specific endopeptidase activity

SENP6 SENP7

3.15e-055362GO:0070139
GeneOntologyMolecularFunctioncysteine-type endopeptidase activity

SENP6 USP10 SENP7

4.97e-0486363GO:0004197
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO1D MYO9A DNAH11

1.25e-03118363GO:0003774
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

SENP6 USP10 SENP7

1.91e-03137363GO:0019783
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO1D MYO9A

2.13e-0338362GO:0000146
GeneOntologyMolecularFunctionATP-dependent activity

XRCC2 MYO1D ATAD2 MYO9A DNAH11

4.63e-03614365GO:0140657
GeneOntologyMolecularFunctioncysteine-type peptidase activity

SENP6 USP10 SENP7

4.95e-03192363GO:0008234
GeneOntologyCellularComponentpresynaptic cytosol

SENP6 HNRNPAB CAMK2A SENP7

1.48e-0649364GO:0099523
GeneOntologyCellularComponentcytosolic region

SENP6 HNRNPAB CAMK2A SENP7

6.26e-0670364GO:0099522
GeneOntologyCellularComponentpostsynaptic cytosol

SENP6 CAMK2A SENP7

6.33e-0545363GO:0099524
HumanPhenoNeuropathic spinal arthropathy

SH3TC2 MYO9A AGRN

9.45e-0623103HP:0008443
HumanPhenoFrontalis muscle weakness

MYO9A AGRN

1.55e-0410102HP:0004661
HumanPhenoAbnormal frontalis muscle physiology

MYO9A AGRN

1.55e-0410102HP:3000004
HumanPhenoAbnormality of occipitofrontalis muscle

MYO9A AGRN

1.55e-0410102HP:0040172
HumanPhenoCranial nerve paralysis

SH3TC2 XRCC2 MYO9A AGRN NAXE

2.10e-04329105HP:0006824
HumanPhenoAbnormal cranial nerve physiology

SH3TC2 XRCC2 MYO9A AGRN NAXE

2.19e-04332105HP:0031910
HumanPhenoAbnormal morphology of the musculature of the neck

VPS13D MYO9A AGRN NAXE

2.20e-04171104HP:0011006
HumanPhenoApneic episodes precipitated by illness, fatigue, stress

MYO9A AGRN

2.27e-0412102HP:0002872
HumanPhenoNarrow jaw

MYO9A AGRN

2.67e-0413102HP:0012801
HumanPhenoIntermittent episodes of respiratory insufficiency due to muscle weakness

MYO9A AGRN

3.12e-0414102HP:0004889
HumanPhenoNasal regurgitation

MYO9A AGRN

3.12e-0414102HP:0011469
HumanPhenoAbnormal cranial nerve morphology

SH3TC2 XRCC2 MYO9A AGRN NAXE

3.89e-04375105HP:0001291
HumanPhenoChoking episodes

MYO9A AGRN

4.64e-0417102HP:0030842
HumanPhenoSudden episodic apnea

MYO9A AGRN

5.83e-0419102HP:0002882
HumanPhenoDistal amyotrophy

SH3TC2 VPS13D MYO9A AGRN

6.86e-04230104HP:0003693
HumanPhenoFacial palsy

SH3TC2 XRCC2 MYO9A AGRN

7.09e-04232104HP:0010628
HumanPhenoEpisodic respiratory distress

MYO9A AGRN

7.14e-0421102HP:0004885
HumanPhenoAbnormal seventh cranial physiology

SH3TC2 XRCC2 MYO9A AGRN

7.20e-04233104HP:0010827
HumanPhenoAnti-acetylcholine receptor antibody positivity

MYO9A AGRN

7.85e-0422102HP:6001064
HumanPhenoAnti-neuromuscular Junction acetylcholine receptor antibody positivity

MYO9A AGRN

7.85e-0422102HP:0030208
HumanPhenoStaring gaze

MYO9A AGRN

7.85e-0422102HP:0025401
DomainPeptidase_C48

SENP6 SENP7

7.54e-057362PF02902
DomainULP_PROTEASE

SENP6 SENP7

7.54e-057362PS50600
DomainPeptidase_C48_C

SENP6 SENP7

7.54e-057362IPR003653
DomainMYOSIN_MOTOR

MYO1D MYO9A

2.43e-0338362PS51456
DomainMyosin_head

MYO1D MYO9A

2.43e-0338362PF00063
DomainMyosin_head_motor_dom

MYO1D MYO9A

2.43e-0338362IPR001609
DomainMYSc

MYO1D MYO9A

2.43e-0338362SM00242
DomainCa/CaM-dep_Ca-dep_prot_Kinase

DCLK3 CAMK2A

7.81e-0369362IPR020636
DomainIQ

MYO1D MYO9A

8.26e-0371362PF00612
Pubmed

MYO9A deficiency in motor neurons is associated with reduced neuromuscular agrin secretion.

MYO9A AGRN

1.04e-06236229462312
Pubmed

Genetic heterogeneity in Leigh syndrome: Highlighting treatable and novel genetic causes.

VPS13D NAXE

1.04e-06236232020600
Pubmed

Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7.

SENP6 SENP7

1.04e-06236218799455
Pubmed

Neuronal Localization of SENP Proteins with Super Resolution Microscopy.

SENP6 SENP7

3.12e-06336233113832
Pubmed

Swapping small ubiquitin-like modifier (SUMO) isoform specificity of SUMO proteases SENP6 and SENP7.

SENP6 SENP7

1.04e-05536221878624
Pubmed

SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation.

SULF1 S100A1

3.73e-05936217720696
Pubmed

Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns.

HHIP MYO1D

6.83e-051236225006744
Pubmed

Nuclear EGFR renders cells radio-resistant by binding mRNA species and triggering a metabolic switch to increase lactate production.

MYO9A HNRNPAB

1.08e-041536226320552
Pubmed

Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome.

AGRN CAMK2A

1.96e-042036216635246
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

TDRD5 TGM2 RNMT MYO9A RPN2 HNRNPAB

2.10e-0484436625963833
Pubmed

Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.

RPN2 HNRNPAB NAXE

2.32e-0411536320000738
Pubmed

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.

SENP6 ATAD2 AP1S3 HNRNPAB

2.77e-0430636418973680
Pubmed

Congenital Myasthenic Syndromes Overview

MYO9A AGRN

3.33e-042636220301347
Pubmed

The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation.

AGRN CAMK2A

3.87e-042836224448406
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

USP10 PLCL1 MYO1D MYO9A HNRNPAB CAMK2A DNAH11

5.76e-04143136737142655
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

RPN2 AGRN ITFG1

6.56e-0416436332409323
Pubmed

A neurogenomics approach to gene expression analysis in the developing brain.

RNMT HNRNPAB CAMK2A

7.28e-0417036315582152
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

SEC14L3 TGM2 MYO1D AGRN NAXE ITFG1

7.39e-04107036623533145
Pubmed

Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.

USP10 KCTD2

8.33e-04413628724849
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

TGM2 PLCL1 KCTD2 HNRNPAB DNAH11

8.84e-0473036534857952
Pubmed

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.

TGM2 MYO1D RPN2 HNRNPAB

9.18e-0442136434650049
Cytoband5q32

SH3TC2 CAMK2A

8.34e-04543625q32
CytobandEnsembl 112 genes in cytogenetic band chr5q32

SH3TC2 CAMK2A

1.82e-0380362chr5q32
Cytoband1q21

NAXE S100A1

2.34e-03913621q21
GeneFamilySUMO specific peptidases

SENP6 SENP7

3.84e-057252984
CoexpressionAtlaskidney_adult_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_500

PLCL1 MYO1D SULF1 ITFG1

3.15e-05110354gudmap_kidney_adult_Podocyte_MafB_k1_500
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D AP1S3 MYO9A GALNT18 DNAH11

4.10e-0718836563a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HHIP FAM124A PLCL1 MYO1D S100A1

4.67e-07193365947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HHIP FAM124A PLCL1 MYO1D S100A1

5.16e-0719736582b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellMacroglial-Oligodendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

SH3TC2 HHIP FAM124A PLCL1 MYO1D

5.56e-072003654dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCellMacroglial-Oligodendrocytes-OPALIN---|Macroglial / cells hierarchy compared to all cells using T-Statistic

SH3TC2 HHIP FAM124A PLCL1 MYO1D

5.56e-072003651314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCellMacroglial-Oligodendrocytes-OPALIN-|Macroglial / cells hierarchy compared to all cells using T-Statistic

SH3TC2 HHIP FAM124A PLCL1 MYO1D

5.56e-072003658b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCellMacroglial-Oligodendrocytes-OPALIN----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

SH3TC2 HHIP FAM124A PLCL1 MYO1D

5.56e-07200365272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCellMacroglial-Oligodendrocytes-OPALIN--|Macroglial / cells hierarchy compared to all cells using T-Statistic

SH3TC2 HHIP FAM124A PLCL1 MYO1D

5.56e-0720036526b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCellMacroglial-Oligodendrocytes-OPALIN|Macroglial / cells hierarchy compared to all cells using T-Statistic

SH3TC2 HHIP FAM124A PLCL1 MYO1D

5.56e-072003655f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SH3TC2 HHIP FAM124A PLCL1 MYO1D

5.56e-07200365829978708463a7459fe1041bd90196775bc4b531
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D MYO9A GALNT18 DNAH11

7.90e-061583641cefb82b9bf79c687a119be568cfc15b14c6e040
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

AP1S3 AGRN SULF1 GALNT18

8.72e-0616236457d627259d27f39885bf416d74bcb6656db6e27b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCLK3 SH3TC2 XRCC2 ATAD2

1.16e-0517436484da9faff088d05233183b425385beb054c92d1b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HHIP XRCC2 ATAD2 HASPIN

1.24e-05177364f925a15d2162d166a5b60edac3517c6b2d6cfbea
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D MYO9A GALNT18 DNAH11

1.44e-05184364da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

MYO1D AP1S3 AGRN GALNT18

1.50e-0518636409d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SH3TC2 MYO9A GALNT18 DNAH11

1.50e-051863645c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HHIP FAM124A PLCL1 MYO1D

1.70e-051923643ce5dbde41aeb73d49f2c7991d34682f0827fa5a
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HHIP FAM124A XRCC2 ATAD2

1.74e-05193364516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D AP1S3 MYO9A GALNT18

1.74e-05193364263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D AP1S3 MYO9A GALNT18

1.77e-05194364e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGM2 HHIP CSMD3 SULF1

1.84e-0519636485507488f83d8f71b3ee2ad5e5aa0b6ad6193873
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLCL1 AP1S3 AGRN GALNT18

1.88e-051973648d5097898dd01cedb04cb694cb480c931e08462c
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TGM2 XRCC2 SLC17A3 SULF1

1.92e-0519836488b4662be9cc933a402c52673fa5e00fa979c0db
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGM2 HHIP CSMD3 SULF1

1.92e-0519836409be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HHIP FAM124A PLCL1 S100A1

1.92e-05198364bdabdb11217ea16e5863aa6bfb0f04d48b17f81e
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TGM2 SLC17A3 SULF1 GALNT18

1.92e-05198364002424b24dacac553e02d0f764a6e8a1e567b9df
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TGM2 FAM124A SULF1 GALNT18

1.96e-051993643a4deea6e11a0555d27497b7c9983350797aac69
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HHIP FAM124A PLCL1 S100A1

2.00e-052003640bfd41c12887479ceb62c3db0a3c3ba5007eb62b
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HHIP FAM124A PLCL1 S100A1

2.00e-05200364159377d904394d91e09913131e9a93e08189955a
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HHIP FAM124A PLCL1 S100A1

2.00e-05200364d30316836494f33ca46d4e415fd2ed179e9cb5ee
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TGM2 FAM124A SULF1 MYOM3

2.00e-052003645ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SH3TC2 HHIP PLCL1 MYO1D

2.00e-05200364acdef0b9096c774040948fc75621ff2b08ea2ee8
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RNMT MYO1D MYO9A FGD3

2.00e-05200364ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SH3TC2 HHIP PLCL1 MYO1D

2.00e-05200364091a18d6efed81cab99955c3047f172170f70476
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SH3TC2 HHIP PLCL1 MYO1D

2.00e-052003643b8513defe25262ab4b492345b2628570eaefd17
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf|Hippocampus / BrainAtlas - Mouse McCarroll V32

SH3TC2 HHIP MYO1D

1.64e-04132363dc6edfa821a1cdc645668b0af5ba5ff80dee10bd
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2|Hippocampus / BrainAtlas - Mouse McCarroll V32

SH3TC2 HHIP MYO1D

1.64e-0413236360ced08bda5efc95a6f116cd0c6d1a779d99ed38
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Serpinb1a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SH3TC2 HHIP S100A1

1.83e-04137363ca8fdbe66a854e6283b22179ec9359ea9e86cd8e
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE|Hippocampus / BrainAtlas - Mouse McCarroll V32

SH3TC2 HHIP MYO1D

1.83e-041373635e97480f014f1d9267e8126f1d0e58acd22f36aa
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SH3TC2 FAM124A ATAD2

2.21e-041463632d907e50206c4762a8baa741363bc7f0a04bd84e
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SH3TC2 HHIP S100A1

2.30e-04148363d60f93311cfa718d026a0dbf61771bbbcbb79146
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SH3TC2 HHIP S100A1

2.30e-0414836344128692824ca419fface0af41099c17135933ce
ToppCell368C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

XRCC2 SULF1 HASPIN

2.39e-04150363c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell368C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

XRCC2 SULF1 HASPIN

2.39e-0415036378b8029e71d26f336a46274c8afef3435bf536b9
ToppCellfacs-Trachea-24m-Hematologic-myeloid-granulocyte-granulocyte_l26|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DCLK3 AP1S3 GALNT18

2.68e-04156363da5cfa8fa9595613f04ce9511f8b42bad34d995a
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TGM2 SLC17A3 SULF1

2.73e-04157363275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TDRD5 FAM124A SULF1

2.89e-041603638590281165eab6514a9f6a022b900d4c222c1044
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 CSMD3 MYO9A

2.94e-04161363b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 CSMD3 MYO9A

2.94e-04161363f7a89c481f789f624102857be722c95fbeb47595
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TDRD5 SLC17A3 CSMD3

3.00e-04162363bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

XRCC2 SULF1 HASPIN

3.00e-04162363e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

XRCC2 SULF1 HASPIN

3.00e-04162363ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CRLS1 AP1S3 MYO9A

3.11e-041643631cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCLK3 XRCC2 ATAD2

3.22e-041663632642544070564debe2deb2938d2c33997bf5ef02
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HHIP CSMD3 SULF1

3.22e-041663633b67064a5149e72f895344d938c64b8ff65247f5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SH3TC2 XRCC2 ATAD2

3.34e-04168363d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D231|Adult / Lineage, Cell type, age group and donor

FAM124A SULF1 MYOM3

3.34e-04168363aca34c51758c65925ad24110294a72b2dea6db72
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLCL1 ATAD2 FGD3

3.39e-041693638caf7996796a2e2716e3855de855c903d6126bf2
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HHIP CSMD3 SULF1

3.45e-04170363a7184dc41f90caa753860ed0f65a18133f84bc5f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HHIP CSMD3 SULF1

3.45e-04170363b5b47fe42617a4c2ebb49c8ed55db3926213a75a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

XRCC2 ATAD2 SULF1

3.51e-04171363b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

XRCC2 ATAD2 SULF1

3.51e-04171363b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC17A3 CAMK2A MYOM3

3.51e-04171363f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 AGRN GALNT18

3.63e-0417336345808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

TGM2 SLC17A3 GALNT18

3.63e-0417336322200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

TGM2 SLC17A3 GALNT18

3.63e-04173363ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD2 AP1S3 DNAH11

3.63e-0417336315af4a0f7516dbf5c93ba66a19aca073ebe30d04
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HHIP CRLS1 SULF1

3.63e-0417336330d67738633493d47f06ae452424382f069b6c0a
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD2 AP1S3 HASPIN

3.63e-041733636c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 AGRN GALNT18

3.63e-041733637fa9dbcb258c3ab974490063951620e2def03db1
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HHIP CRLS1 SULF1

3.70e-04174363a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGM2 HHIP SULF1

3.70e-041743634da79da7a09ee1e345102c5331675ebcdbe56171
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCLK3 SH3TC2 ATAD2

3.70e-04174363dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellInfluenza_Severe-Plasmablast|Influenza_Severe / Disease group and Cell class

MYO1D GALNT18 HASPIN

3.76e-041753633f9b9793d3d1b7a9b97899272b6a0d37b05c11d1
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 USP10 CRLS1

3.76e-04175363711ace94fa9a763c6ae48171a690953f25deebe4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A GALNT18 DNAH11

3.82e-04176363327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TGM2 SULF1 MYOM3

3.82e-0417636352af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCellfacs-Aorta|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC14L3 TGM2 DNAH11

3.82e-041763630b3491451be02c18a16cdb875645be47eb867a7f
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TGM2 SULF1 GALNT18

3.88e-041773635ff8dcfb030312126695d53a026d2e104a401b83
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D MYO9A DNAH11

3.88e-04177363da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D MYO9A DNAH11

3.95e-04178363c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

XRCC2 ATAD2 HASPIN

4.01e-0417936388d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TGM2 SULF1 MYOM3

4.01e-041793638c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLCL1 CSMD3 DNAH11

4.08e-04180363cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellIPF-Epithelial-Mesothelial|IPF / Disease state, Lineage and Cell class

SH3TC2 SULF1 GALNT18

4.08e-041803631fa54bf4dba72866b2295639d991af639341bc08
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A GALNT18 DNAH11

4.15e-041813636a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DNAH11 HASPIN S100A1

4.15e-041813633aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DNAH11 HASPIN S100A1

4.15e-04181363997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell5'-Adult-Appendix-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DNAH11 HASPIN S100A1

4.15e-04181363e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1D MYO9A AGRN

4.15e-04181363b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellPBMC-Control-cDC_12|Control / Compartment, Disease Groups and Clusters

XRCC2 ATAD2 HASPIN

4.21e-041823634774066d0f9986abc3d13a2a3bc99ce4f1327ae0
ToppCell(00)_Basal-(0)_uninjured|(00)_Basal / shred by cell type and Timepoint

SEC14L3 AGRN SULF1

4.21e-04182363c02c9cab4389d80f318f4bb8d703c1e719672624
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SH3TC2 GALNT18 DNAH11

4.21e-041823635e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AP1S3 MYO9A DNAH11

4.28e-04183363cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TGM2 HHIP SULF1

4.28e-04183363274f274cf60daa30d6a4cd603a3af7823bfb8016
ToppCellIPF-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

SH3TC2 SULF1 GALNT18

4.28e-041833637df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCellCV-Severe-3|CV / Virus stimulation, Condition and Cluster

XRCC2 HNRNPAB HASPIN

4.35e-041843631c9bda00bb6efd98f68781ca06655bf6c4282f27
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TGM2 HHIP SULF1

4.35e-04184363607b55022de21ddb6a2d75e085df76df7abf6624
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

TGM2 SLC17A3 GALNT18

4.35e-041843630f19494789f38ab1a420545e15e748ca7eb345c3
Diseasehip bone size

HHIP PLCL1 AGRN

6.92e-0565363EFO_0004844
DiseaseCongenital Myasthenic Syndromes, Presynaptic

MYO9A AGRN

2.44e-0419362C0751884
Diseaselate-onset Alzheimers disease

USP10 PLCL1 AGRN SENP7

4.31e-04292364EFO_1001870
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

DCLK3 TGM2 CSMD3

7.82e-04148363C0279702
Diseaseasthma

USP10 PLCL1 CSMD3 AP1S3 SENP7

2.07e-03751365MONDO_0004979
DiseaseAbnormality of chromosome segregation

RNMT AGRN

2.45e-0360362HP_0002916
Diseasemucocutaneous lymph node syndrome

RPN2 GALNT18

3.90e-0376362EFO_0004246
Diseaseexploratory eye movement measurement

SH3TC2 GALNT18

4.41e-0381362EFO_0007700

Protein segments in the cluster

PeptideGeneStartEntry
VGVVDEYVDGILNIF

TDRD5

621

Q8NAT2
VIQINFEEFDLEIGY

CSMD3

586

Q7Z407
GVLELEGVEGQELFY

AGRN

1136

O00468
IYVEFIDDIVVEGFF

DNAH11

906

Q96DT5
EVQELFIRDYGEIFN

ATAD2

906

Q6PL18
YFILDEFIIGGEIQE

AP1S3

111

Q96PC3
GLLFYLIFGEADVQE

SLC17A3

396

O00476
IDELYELVVDAIFGF

NAXE

176

Q8NCW5
LEYVQGGDLFDAIIE

DCLK3

431

Q9C098
LAVVLFLQEEYGEEQ

FAM124A

101

Q86V42
LLEVYEQLGGEEDIV

FGD3

351

Q5JSP0
VDRQYFQEIGLLDEG

GALNT18

336

Q6P9A2
DDQLFIVLEFEFGGI

HASPIN

596

Q8TF76
NLEGVVDVPEFLVYF

RNMT

361

O43148
PLVEVYQEFFGLLEE

SEC14L3

166

Q9UDX4
YLIIEEDFNIALGVF

CRLS1

126

Q9UJA2
LAEEGVLEEAEFYNI

KCTD2

146

Q14681
EEGEFLNDVIIDFYL

SENP7

771

Q9BQF6
REYFGEFGEIEAIEL

HNRNPAB

171

Q99729
GDGEVDFQEYVVLVA

S100A1

66

P23297
VFYTGVNDDGLEELV

TAAR8

166

Q969N4
ELNFYQGESIEIIGF

SH3TC2

286

Q8TF17
FVGELNFGLVEVVYE

SKIV2L

1161

Q15477
YLIFDLVTGGELFED

CAMK2A

86

Q9UQM7
ILGFGEDELGEVYIL

HHIP

551

Q96QV1
LLIEYFRNEFGEIQG

TGM2

311

P21980
FVVLDDDYIGDEFIG

PLCL1

796

Q15111
LDELGGVYLQFEEGL

RPN2

191

P04844
LNEGEFLNDVIIDFY

SENP6

676

Q9GZR1
EGGLEVEVLFIDTDY

XRCC2

71

O43543
GQEYQRIEFGVDEVI

USP10

51

Q14694
YIEFGFVAVIDGEVL

ZBED9

741

Q6R2W3
FFDIYEDGILDIVVL

ITFG1

401

Q8TB96
LSVEFEGEIYDINLE

SULF1

546

Q8IWU6
EPFILEENEIYGFDL

VPS13D

1351

Q5THJ4
NTVIGVLDIYGFEIF

MYO1D

376

O94832
LSIGVLDIFGFEDYE

MYO9A

531

B2RTY4
EVGVDEEGFIYLAFE

MYOM3

906

Q5VTT5