Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	L-leucine binding	UBR2 SESN1	9.01e-05	7	42	2	GO:0070728
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR5D16 FCRLB OR52K1 OR52K2 PTPRG CRCP TREML1 OR2AP1 OR6C75 IFNAR1	3.93e-04	1353	42	10	GO:0004888
HumanPheno	Failure of eruption of permanent teeth	FLNB SMCHD1	2.77e-05	5	9	2	HP:0006352
Domain	-	SACS SMCHD1	8.29e-04	20	40	2	3.30.565.10
Domain	HATPase_C	SACS SMCHD1	9.15e-04	21	40	2	IPR003594
Domain	Olfact_rcpt	OR5D16 OR52K1 OR52K2 OR2AP1 OR6C75	1.44e-03	393	40	5	IPR000725
Pubmed	Introns in sequence tags.	MYO5A IFNAR1	8.53e-06	4	42	2	1350660
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR5D16 OR52K1 OR52K2 OR2AP1 OR6C75	5.48e-05	340	42	5	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR5D16 OR52K1 OR52K2 OR2AP1 OR6C75	5.48e-05	340	42	5	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR5D16 OR52K1 OR52K2 OR2AP1 OR6C75	5.71e-05	343	42	5	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR5D16 OR52K1 OR52K2 OR2AP1 OR6C75	5.95e-05	346	42	5	14611657
Pubmed	HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease.	PRKAG2 PLCE1	3.54e-04	23	42	2	9730685
Pubmed	The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases.	PRKAG2 PLCE1	3.54e-04	23	42	2	9278385
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	UBR2 FLNB PHLDB1 PRKAG2 PTPRG MYO5A LRRC8D SESN1	3.56e-04	1489	42	8	28611215
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	ADAMTS20 MCM3 CRCP LGSN SMCHD1	3.71e-04	513	42	5	25798074
Pubmed	HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.	MCM3 FLNB	6.90e-04	32	42	2	27114546
Pubmed	Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse.	OR52K1 OR52K2	7.34e-04	33	42	2	17350283
Pubmed	HIV gp120 induced gene expression signatures in vaginal epithelial cells.	CAPN14 TREML1	8.26e-04	35	42	2	23867815
Pubmed	The DNA sequence and analysis of human chromosome 6.	UBR2 MCM3 LGSN TREML1 ENPP3	8.87e-04	622	42	5	14574404
Cytoband	15q21	MYO5A RNF111	4.47e-05	11	42	2	15q21
Cytoband	12q13.2	OR2AP1 OR6C75	1.18e-03	55	42	2	12q13.2
Cytoband	6p21.1	UBR2 TREML1	2.47e-03	80	42	2	6p21.1
Disease	Thromboembolism	OR52K1 OR52K2	1.64e-03	44	40	2	HP_0001907
Disease	open-angle glaucoma	PRKAG2 KLF5 PLCE1	2.21e-03	191	40	3	EFO_0004190
Disease	optic cup area measurement	FLNB PLCE1	2.63e-03	56	40	2	EFO_0006940
Disease	gut microbiome measurement, taxonomic microbiome measurement	NAPG FLNB	3.64e-03	66	40	2	EFO_0007874, EFO_0007883
Disease	cortical thickness	ADAMTS20 FLNB PHLDB1 PRKAG2 AFAP1L1 PLCE1	3.64e-03	1113	40	6	EFO_0004840
Disease	aortic measurement	CCDC175 FLNB PLCE1	4.76e-03	251	40	3	EFO_0020865
Disease	descending aortic diameter	FLNB PLCE1	6.37e-03	88	40	2	EFO_0021788

Protein segments in the cluster

Peptide	Gene	Start	Entry
IIVTLKSTKIHACYT	PTPRG	976	P23470
RSHKCYDIVPTSSKL	PRKAG2	266	Q9UGJ0
RITYCTEIPSTKKHK	ADAMTS20	1611	P59510
YTLTGIRKVTCKHRP	CAPN14	256	A8MX76
LPAYVKVCHSKVRAL	DENND4A	776	Q7Z401
YCVPNSKNSRHTVKV	OR5D16	261	Q8NGK9
YKCVVKQGHTLFVPT	KDM7A	336	Q6ZMT4
CSYTPVKAIKHTIAV	FLNB	706	O75369
KIGVYSPVHCIKTTV	IFNAR1	211	P17181
LKPLTVYCVKARAHT	IFNAR1	396	P17181
KPLHYTTIMSSRICI	OR2AP1	126	Q8NGE2
VVRSVHYCPATKKTI	MCM3	141	P25205
TRVHFPVVKCTEKNT	CCDC175	776	P0C221
IPTHYFVVLTSCKNK	ENPP3	776	O14638
HTVDCYISRPTEKKV	GJB4	171	Q9NTQ9
HKKSIEVQTPGVYRC	FCRLB	71	Q6BAA4
KKTPSNNITCVTYHV	SACS	361	Q9NZJ4
VKDTTVKYCHADIPR	SACS	2476	Q9NZJ4
YPKTCSKVEHFVSIL	LRRC8D	186	Q7L1W4
TRKKVTKPYVCSTEV	LGSN	31	Q5TDP6
KPLHYTIIMSTRVCT	OR6C75	126	A6NL08
RCIHKPTSQEYAVKV	PHKG1	36	Q16816
VAICKPLHYTTVLTG	OR52K1	126	Q8NGK4
VAICKPLHYTKVLTG	OR52K2	126	Q8NGK3
GHCYKLVSIISKTVV	GAREM2	286	Q75VX8
KYISKTPCRHQSPEI	CRCP	51	O75575
RSFKVYIKTVVCTPE	SESN1	431	Q9Y6P5
YIKTVVCTPEKVTKR	SESN1	436	Q9Y6P5
YRKEVVKITHCPTLL	SMCHD1	1846	A6NHR9
SAIIRTPKCYHISSL	PLCE1	1746	Q9P212
DTCSIIYVPKDSRHK	AFAP1L1	266	Q8TED9
VKISCIFYHSKPRNI	C12orf50	21	Q8NA57
TVKHAKVYTCTICSR	ZNF384	426	Q8TF68
VVKACKHYLTTRTLP	ZBTB5	111	O15062
VTPNCNYLTSVIKKH	RNASE10	186	Q5GAN6
TIERCTYPHKYKKVT	RNF111	901	Q6ZNA4
PTCYKKTIAQVLVHL	NAPG	191	Q99747
TLTGVKYHRCVKPSS	ZNF577	126	Q9BSK1
KTCPVIISSTAHYSK	THNSL1	656	Q8IYQ7
HVVLSSKVCRGYLVK	PHLDB1	1251	Q86UU1
KVLVCSKPVTYATVI	TREML1	271	Q86YW5
YCVSQEKVSIHLPVS	UBR2	601	Q8IWV8
VRIQTHRSEKPYKCK	ZNF266	201	Q14584
YKSQRPCVTHIKTEP	KLF5	151	Q13887
CHRKLATATETYIKP	MYO5A	376	Q9Y4I1