Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein serine kinase activity	MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN LRRK1 STK32C CIT CDK10 ATM MAPK6 STK38L	2.18e-05	363	258	16	GO:0106310
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	HIP1 CD2AP SPTBN1 ANK1 ANK3 MYOM2 POTEJ EPB41 MYBPC2	4.93e-05	130	258	9	GO:0005200
GeneOntologyMolecularFunction	ATP-dependent activity	MYO1G ATP7B MYO1A MYO1D ABCA13 AK9 MYO3A DDX46 KIF19 ABCD3 TOR1B DNAH5 DHX58 SMC6 RNF213 NLRP1 DMC1 CCT6A MYO15A ATP4A TOP2B	5.22e-05	614	258	21	GO:0140657
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	PHKA1 MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN LRRK1 STK32C CIT CDK10 ATM MAPK6 STK38L	7.49e-05	446	258	17	GO:0004674
GeneOntologyMolecularFunction	phosphatidylinositol-3,4-bisphosphate binding	MYO1G HIP1 NCF1 NCF1C NCF1B	8.19e-05	35	258	5	GO:0043325
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	PIGN PAPOLB AK9 TRRAP TXK JAK3 PHKA1 MYO3A TTBK1 BRAF DSTYK STK24 VRK1 TUT4 RPS6KA4 CDC42BPA KALRN DOLK LRRK1 STK32C CIT CDK10 POLR3C ATM MAPK6 TNKS2 STK38L	8.80e-05	938	258	27	GO:0016772
GeneOntologyMolecularFunction	microfilament motor activity	MYO1G MYO1A MYO1D MYO3A MYO15A	1.23e-04	38	258	5	GO:0000146
GeneOntologyMolecularFunction	formate-tetrahydrofolate ligase activity	MTHFD1L MTHFD1	1.66e-04	2	258	2	GO:0004329
GeneOntologyMolecularFunction	thromboxane A2 receptor binding	RPGRIP1 RPGRIP1L	1.66e-04	2	258	2	GO:0031870
GeneOntologyMolecularFunction	superoxide-generating NADPH oxidase activator activity	NCF1 NCF1C NCF1B	2.39e-04	10	258	3	GO:0016176
GeneOntologyMolecularFunction	protein kinase activity	TXK JAK3 PHKA1 MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN LRRK1 STK32C CIT CDK10 ATM MAPK6 STK38L	3.17e-04	600	258	19	GO:0004672
GeneOntologyMolecularFunction	kinase activity	AK9 TRRAP TXK JAK3 PHKA1 MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN DOLK LRRK1 STK32C CIT CDK10 ATM MAPK6 STK38L	4.02e-04	764	258	22	GO:0016301
GeneOntologyMolecularFunction	superoxide-generating NAD(P)H oxidase activity	NCF1 NCF1C NCF1B	4.30e-04	12	258	3	GO:0016175
GeneOntologyMolecularFunction	prostanoid receptor binding	RPGRIP1 RPGRIP1L	4.95e-04	3	258	2	GO:0031862
GeneOntologyMolecularFunction	heparan sulfate 6-O-sulfotransferase activity	HS6ST2 HS6ST1	4.95e-04	3	258	2	GO:0017095
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATP7B ABCA13 AK9 DDX46 KIF19 ABCD3 TOR1B DNAH5 DHX58 SMC6 RNF213 NLRP1 DMC1 CCT6A ATP4A	6.55e-04	441	258	15	GO:0016887
GeneOntologyMolecularFunction	actin filament binding	MYO1G HIP1 MYO1A MYO1D CD2AP SPTBN1 MYO3A FLNC FHOD3 MYO15A	7.71e-04	227	258	10	GO:0051015
GeneOntologyMolecularFunction	calmodulin binding	MYO1G MYO1A MYO1D SPTBN1 RYR3 PHKA1 MYO3A GRIN1 MYO15A EPB41	8.52e-04	230	258	10	GO:0005516
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO1G MYO1A MYO1D MYO3A KIF19 DNAH5 MYO15A	8.65e-04	118	258	7	GO:0003774
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	TXK JAK3 PHKA1 MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN DOLK LRRK1 STK32C CIT CDK10 ATM MAPK6 STK38L	9.46e-04	709	258	20	GO:0016773
GeneOntologyMolecularFunction	histone H3S10 kinase activity	VRK1 RPS6KA4	9.81e-04	4	258	2	GO:0035175
GeneOntologyMolecularFunction	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	MTHFD1L MTHFD1	9.81e-04	4	258	2	GO:0004486
GeneOntologyMolecularFunction	methylenetetrahydrofolate dehydrogenase (NADP+) activity	MTHFD1L MTHFD1	9.81e-04	4	258	2	GO:0004488
GeneOntologyMolecularFunction	actin binding	MYO1G HIP1 MYO1A MYO1D CD2AP SPTBN1 MYO3A SYNE2 FLNC FHOD3 LRRC27 MYO15A STK38L EPB41 MYBPC2	1.50e-03	479	258	15	GO:0003779
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions	HEPH HEPHL1 MTRR	1.51e-03	18	258	3	GO:0016722
GeneOntologyMolecularFunction	histone H2AX kinase activity	VRK1 ATM	1.62e-03	5	258	2	GO:0141003
GeneOntologyBiologicalProcess	negative regulation of smooth muscle contraction	DOCK4 NCF1 DOCK5 NCF1C NCF1B	6.40e-06	22	257	5	GO:0045986
GeneOntologyBiologicalProcess	neutrophil-mediated killing of gram-positive bacterium	NCF1 NCF1C NCF1B	1.88e-05	5	257	3	GO:0070946
GeneOntologyCellularComponent	spectrin-associated cytoskeleton	SPTBN1 ANK1 ANK3 EPB41	2.56e-06	9	254	4	GO:0014731
GeneOntologyCellularComponent	sarcoplasm	RYR3 ANKRD2 SYNE2 AKAP7 FLNC ANK1 ANK3 CASQ2 THBS1	1.07e-05	114	254	9	GO:0016528
GeneOntologyCellularComponent	interchromatin granule	CPSF6 SMC6 TARDBP	1.74e-05	5	254	3	GO:0035061
GeneOntologyCellularComponent	sarcomere	SPTBN1 RYR3 ANKRD2 SYNE2 FLNC ANK1 ANK3 CASQ2 FHOD3 LRRC27 MYOM2 MYBPC2	5.71e-05	249	254	12	GO:0030017
GeneOntologyCellularComponent	actin cytoskeleton	MYO1G HIP1 MYO1A MYO1D CD2AP SPTBN1 DOCK5 MYO3A FLNC CDC42BPA KALRN FHOD3 CIT ACTR1A AKAP13 POTEJ MYO15A STK38L EPB41	8.62e-05	576	254	19	GO:0015629
GeneOntologyCellularComponent	sarcoplasmic reticulum	RYR3 SYNE2 AKAP7 ANK1 ANK3 CASQ2 THBS1	9.89e-05	88	254	7	GO:0016529
GeneOntologyCellularComponent	axolemma	MYO1D SPTBN1 ANK1 CNTNAP2	1.08e-04	21	254	4	GO:0030673
GeneOntologyCellularComponent	myofibril	SPTBN1 RYR3 ANKRD2 SYNE2 FLNC ANK1 ANK3 CASQ2 FHOD3 LRRC27 MYOM2 MYBPC2	1.37e-04	273	254	12	GO:0030016
GeneOntologyCellularComponent	contractile muscle fiber	SPTBN1 RYR3 ANKRD2 SYNE2 FLNC ANK1 ANK3 CASQ2 FHOD3 LRRC27 MYOM2 MYBPC2	2.39e-04	290	254	12	GO:0043292
GeneOntologyCellularComponent	M band	SPTBN1 ANK1 MYOM2 MYBPC2	5.17e-04	31	254	4	GO:0031430
GeneOntologyCellularComponent	basolateral plasma membrane	ATP7B MYO1A MYO1D HEPH LIN7B DSTYK ANK1 ANK3 TFRC SLC12A2 EPB41 PCMT1	5.78e-04	320	254	12	GO:0016323
GeneOntologyCellularComponent	myosin complex	MYO1G MYO1A MYO1D MYO3A MYO15A	7.47e-04	59	254	5	GO:0016459
GeneOntologyCellularComponent	I band	RYR3 ANKRD2 SYNE2 FLNC ANK1 ANK3 CASQ2 FHOD3	9.86e-04	166	254	8	GO:0031674
GeneOntologyCellularComponent	axoneme	IFT172 LCA5L NME8 KIF19 TEKT1 DNAH5 RPGRIP1 RPGRIP1L TEKT5	1.00e-03	207	254	9	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	IFT172 LCA5L NME8 KIF19 TEKT1 DNAH5 RPGRIP1 RPGRIP1L TEKT5	1.04e-03	208	254	9	GO:0097014
GeneOntologyCellularComponent	NADPH oxidase complex	NCF1 NCF1C NCF1B	1.26e-03	18	254	3	GO:0043020
GeneOntologyCellularComponent	basal plasma membrane	ATP7B MYO1A MYO1D HEPH LIN7B DSTYK ANK1 ANK3 TFRC SLC12A2 EPB41 PCMT1	1.38e-03	354	254	12	GO:0009925
GeneOntologyCellularComponent	sperm cytoplasmic droplet	IFT172 NME8	1.44e-03	5	254	2	GO:0097598
GeneOntologyCellularComponent	MPP7-DLG1-LIN7 complex	LIN7B MPP7	1.44e-03	5	254	2	GO:0097025
GeneOntologyCellularComponent	vesicle tethering complex	VPS33B COG6 VPS8 GRIP1 EXOC2	1.84e-03	72	254	5	GO:0099023
GeneOntologyCellularComponent	cytoplasmic side of plasma membrane	NCF1 RYR3 JAK3 PTPN4 ANK1 NCF1C NCF1B EPB41	1.96e-03	185	254	8	GO:0009898
GeneOntologyCellularComponent	cell cortex	HIP1 MYO1A MYO1D CD2AP SPTBN1 MPP7 ANK1 GRIP1 ACTR1A AKAP13 EXOC2 EPB41	2.04e-03	371	254	12	GO:0005938
GeneOntologyCellularComponent	Cul4B-RING E3 ubiquitin ligase complex	DDB1 CUL4B	2.14e-03	6	254	2	GO:0031465
GeneOntologyCellularComponent	actin-based cell projection	DOCK4 MYO1G MYO1A MYO1D MYO3A SYNE2 SLC26A2 SLC34A2 MYO15A DCXR	2.22e-03	278	254	10	GO:0098858
GeneOntologyCellularComponent	basal part of cell	ATP7B MYO1A MYO1D HEPH LIN7B DSTYK ANK1 ANK3 TFRC SLC12A2 EPB41 PCMT1	2.38e-03	378	254	12	GO:0045178
GeneOntologyCellularComponent	supramolecular fiber	MYO1A CD2AP SPTBN1 RYR3 MYO3A ANKRD2 SYNE2 KIF19 TEKT1 DNAH5 FLNC RPGRIP1L ANK1 ANK3 CASQ2 FHOD3 CCDC57 TEKT5 GRIP1 CCT6A LRRC27 AKAP13 MYOM2 POTEJ DCXR MYBPC2	2.47e-03	1179	254	26	GO:0099512
GeneOntologyCellularComponent	Z disc	RYR3 SYNE2 FLNC ANK1 ANK3 CASQ2 FHOD3	2.52e-03	151	254	7	GO:0030018
GeneOntologyCellularComponent	supramolecular polymer	MYO1A CD2AP SPTBN1 RYR3 MYO3A ANKRD2 SYNE2 KIF19 TEKT1 DNAH5 FLNC RPGRIP1L ANK1 ANK3 CASQ2 FHOD3 CCDC57 TEKT5 GRIP1 CCT6A LRRC27 AKAP13 MYOM2 POTEJ DCXR MYBPC2	2.71e-03	1187	254	26	GO:0099081
GeneOntologyCellularComponent	CORVET complex	VPS33B VPS8	2.97e-03	7	254	2	GO:0033263
MousePheno	liver abscess	NCF1 ANK1 NCF1C NCF1B	1.64e-06	7	209	4	MP:0003332
MousePheno	decreased susceptibility to parasitic infection induced morbidity/mortality	JAK3 BPGM MRC1 ANK1	5.82e-05	15	209	4	MP:0010751
MousePheno	increased heart atrium size	IFT172 NCF1 CASQ2 SEMA3D NCF1C NCF1B	5.91e-05	46	209	6	MP:0008725
MousePheno	increased angiotensin I-converting enzyme activity	NCF1 NCF1C NCF1B	6.37e-05	6	209	3	MP:0003184
MousePheno	abnormal angiotensin I-converting enzyme activity	NCF1 NCF1C NCF1B	6.37e-05	6	209	3	MP:0013254
Domain	Ank_2	CDKN2D GLS2 ANKS1B ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD2 CASKIN1 ANKRD12 ANKRD20A1 ANKS1A SLF1 ANK1 ANK3 POTEG LRRK1 POTEM POTEJ TNKS2 GABPB1	1.78e-11	215	256	20	PF12796
Domain	-	CDKN2D GLS2 ANKS1B ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD2 CASKIN1 ANKRD12 ANKRD20A1 ANKS1A SLF1 ANK1 ANK3 POTEG LRRK1 POTEM AKAP13 POTEJ TNKS2 GABPB1	3.28e-11	248	256	21	1.25.40.20
Domain	Ankyrin_rpt-contain_dom	CDKN2D GLS2 ANKS1B ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD2 CASKIN1 ANKRD12 ANKRD20A1 ANKS1A SLF1 ANK1 ANK3 POTEG LRRK1 POTEM AKAP13 POTEJ TNKS2 GABPB1	5.14e-11	254	256	21	IPR020683
Domain	Ank	CDKN2D GLS2 ANKS1B ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD2 CASKIN1 ANKRD12 ANKRD20A1 ANKS1A SLF1 ANK1 ANK3 POTEG LRRK1 POTEM POTEJ TNKS2 GABPB1	5.19e-11	228	256	20	PF00023
Domain	ANK	CDKN2D GLS2 ANKS1B ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD2 CASKIN1 ANKRD12 ANKRD20A1 ANKS1A SLF1 ANK1 ANK3 POTEG LRRK1 POTEM POTEJ TNKS2 GABPB1	2.90e-10	251	256	20	SM00248
Domain	ANK_REPEAT	CDKN2D GLS2 ANKS1B ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD2 CASKIN1 ANKRD12 ANKRD20A1 ANKS1A SLF1 ANK1 ANK3 POTEG LRRK1 POTEM POTEJ TNKS2 GABPB1	3.34e-10	253	256	20	PS50088
Domain	ANK_REP_REGION	CDKN2D GLS2 ANKS1B ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD2 CASKIN1 ANKRD12 ANKRD20A1 ANKS1A SLF1 ANK1 ANK3 POTEG LRRK1 POTEM POTEJ TNKS2 GABPB1	3.59e-10	254	256	20	PS50297
Domain	Ankyrin_rpt	CDKN2D GLS2 ANKS1B ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD2 CASKIN1 ANKRD12 ANKRD20A1 ANKS1A SLF1 ANK1 ANK3 POTEG LRRK1 POTEM POTEJ TNKS2 GABPB1	6.20e-10	262	256	20	IPR002110
Domain	ARM-type_fold	HIP1 NBEAL1 IFT172 MROH5 TEX10 TRRAP LYST RYR3 DOCK5 ARMC8 DOCK3 DNAJC13 HEATR4 MROH2A FHOD3 IPO9 PPP2R5E ATM	1.10e-06	339	256	18	IPR016024
Domain	DOCK	DOCK4 DOCK5 DOCK6 DOCK3	1.05e-05	11	256	4	IPR026791
Domain	DOCK_C	DOCK4 DOCK5 DOCK6 DOCK3	1.05e-05	11	256	4	IPR010703
Domain	DOCK-C2	DOCK4 DOCK5 DOCK6 DOCK3	1.05e-05	11	256	4	PF14429
Domain	DHR-1_domain	DOCK4 DOCK5 DOCK6 DOCK3	1.05e-05	11	256	4	IPR027007
Domain	DHR_2	DOCK4 DOCK5 DOCK6 DOCK3	1.05e-05	11	256	4	PS51651
Domain	DHR_1	DOCK4 DOCK5 DOCK6 DOCK3	1.05e-05	11	256	4	PS51650
Domain	DHR-2	DOCK4 DOCK5 DOCK6 DOCK3	1.05e-05	11	256	4	PF06920
Domain	DHR-2	DOCK4 DOCK5 DOCK6 DOCK3	1.05e-05	11	256	4	IPR027357
Domain	DOCK_N	DOCK4 DOCK5 DOCK3	2.49e-05	5	256	3	PF16172
Domain	DOCK_N	DOCK4 DOCK5 DOCK3	2.49e-05	5	256	3	IPR032376
Domain	P-loop_NTPase	MYO1G MYO1A MYO1D ABCA13 HS6ST2 AK9 ARL5A MYO3A DDX46 RAB9A HS6ST1 KIF19 ABCD3 TOR1B RAB39B DNAH5 MPP7 DHX58 MTHFD1L SMC6 RNF213 NLRP1 LRRK1 DMC1 NLRP14 MTHFD1 MYO15A	4.30e-05	848	256	27	IPR027417
Domain	Protein_kinase_ATP_BS	TXK JAK3 MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN STK32C CIT CDK10 MAPK6 STK38L	7.32e-05	379	256	16	IPR017441
Domain	Myosin_TH1	MYO1G MYO1A MYO1D	8.55e-05	7	256	3	PF06017
Domain	TH1	MYO1G MYO1A MYO1D	8.55e-05	7	256	3	PS51757
Domain	Myosin_TH1	MYO1G MYO1A MYO1D	8.55e-05	7	256	3	IPR010926
Domain	Ser/Thr_kinase_AS	MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN LRRK1 STK32C CIT CDK10 MAPK6 STK38L	1.29e-04	357	256	15	IPR008271
Domain	S_TKc	MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN LRRK1 STK32C CIT CDK10 MAPK6 STK38L	1.38e-04	359	256	15	SM00220
Domain	PROTEIN_KINASE_ST	MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN LRRK1 STK32C CIT CDK10 MAPK6 STK38L	1.51e-04	362	256	15	PS00108
Domain	MYOSIN_MOTOR	MYO1G MYO1A MYO1D MYO3A MYO15A	1.61e-04	38	256	5	PS51456
Domain	Myosin_head_motor_dom	MYO1G MYO1A MYO1D MYO3A MYO15A	1.61e-04	38	256	5	IPR001609
Domain	Myosin_head	MYO1G MYO1A MYO1D MYO3A MYO15A	1.61e-04	38	256	5	PF00063
Domain	MYSc	MYO1G MYO1A MYO1D MYO3A MYO15A	1.61e-04	38	256	5	SM00242
Domain	Kinase-like_dom	TRRAP TXK JAK3 MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN LRRK1 STK32C CIT CDK10 ATM MAPK6 STK38L	1.84e-04	542	256	19	IPR011009
Domain	Formate_THF_ligase	MTHFD1L MTHFD1	1.87e-04	2	256	2	IPR000559
Domain	FTHFS_2	MTHFD1L MTHFD1	1.87e-04	2	256	2	PS00722
Domain	FTHFS_1	MTHFD1L MTHFD1	1.87e-04	2	256	2	PS00721
Domain	Gonadal	DGCR6 DGCR6L	1.87e-04	2	256	2	IPR010849
Domain	Formate_THF_ligase_CS	MTHFD1L MTHFD1	1.87e-04	2	256	2	IPR020628
Domain	Dopey_N	DOP1B DOP1A	1.87e-04	2	256	2	PF04118
Domain	DGCR6	DGCR6 DGCR6L	1.87e-04	2	256	2	PF07324
Domain	RPGRIP1_fam	RPGRIP1 RPGRIP1L	1.87e-04	2	256	2	IPR031139
Domain	ANKS1	ANKS1B ANKS1A	1.87e-04	2	256	2	IPR033635
Domain	C2-C2_1	RPGRIP1 RPGRIP1L	1.87e-04	2	256	2	IPR021656
Domain	FTHFS	MTHFD1L MTHFD1	1.87e-04	2	256	2	PF01268
Domain	C2-C2_1	RPGRIP1 RPGRIP1L	1.87e-04	2	256	2	PF11618
Domain	Dopey_N	DOP1B DOP1A	1.87e-04	2	256	2	IPR007249
Domain	SH3	DOCK4 STAM2 CD2AP NCF1 TXK DOCK5 CASKIN1 MPP7 DOCK3 KALRN MYO15A	2.02e-04	216	256	11	PS50002
Domain	SH3	DOCK4 STAM2 CD2AP NCF1 TXK DOCK5 CASKIN1 MPP7 DOCK3 KALRN MYO15A	2.02e-04	216	256	11	SM00326
Domain	PROTEIN_KINASE_ATP	TXK JAK3 MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN LRRK1 STK32C CIT CDK10 MAPK6 STK38L	2.12e-04	459	256	17	PS00107
Domain	SH3_domain	DOCK4 STAM2 CD2AP NCF1 TXK DOCK5 CASKIN1 MPP7 DOCK3 KALRN MYO15A	2.37e-04	220	256	11	IPR001452
Domain	Pkinase	MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN LRRK1 STK32C CIT CDK10 MAPK6 STK38L	2.62e-04	381	256	15	PF00069
Domain	Prot_kinase_dom	TXK JAK3 MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN LRRK1 STK32C CIT CDK10 MAPK6 STK38L	4.40e-04	489	256	17	IPR000719
Domain	PROTEIN_KINASE_DOM	TXK JAK3 MYO3A TTBK1 BRAF DSTYK STK24 VRK1 RPS6KA4 CDC42BPA KALRN LRRK1 STK32C CIT CDK10 MAPK6 STK38L	4.83e-04	493	256	17	PS50011
Domain	Heparan_SO4-6-sulfoTrfase	HS6ST2 HS6ST1	5.56e-04	3	256	2	IPR010635
Domain	MULTICOPPER_OXIDASE2	HEPH HEPHL1	5.56e-04	3	256	2	PS00080
Domain	PH_dom-like	NBEAL1 SPTBN1 ANKS1B LYST JAK3 PTPN4 PREX1 ANKS1A CDC42BPA KALRN CIT RANBP3L AKAP13 ARHGEF3 EPB41	8.34e-04	426	256	15	IPR011993
Domain	THF_DHG_CYH_C	MTHFD1L MTHFD1	1.10e-03	4	256	2	PF02882
Domain	Cu-oxidase_2	HEPH HEPHL1	1.10e-03	4	256	2	IPR011706
Domain	THF_DH/CycHdrlase_cat_dom	MTHFD1L MTHFD1	1.10e-03	4	256	2	IPR020630
Domain	THF_DH/CycHdrlase_NAD-bd_dom	MTHFD1L MTHFD1	1.10e-03	4	256	2	IPR020631
Domain	THF_DHG_CYH	MTHFD1L MTHFD1	1.10e-03	4	256	2	PF00763
Domain	Cu-oxidase_2	HEPH HEPHL1	1.10e-03	4	256	2	PF07731
Domain	THF_DH/CycHdrlase	MTHFD1L MTHFD1	1.10e-03	4	256	2	IPR000672
Domain	SH3_2	DOCK4 CD2AP CASKIN1 MPP7 DOCK3 MYO15A	1.18e-03	86	256	6	PF07653
Domain	SH3_2	DOCK4 CD2AP CASKIN1 MPP7 DOCK3 MYO15A	1.18e-03	86	256	6	IPR011511
Domain	Pkinase_C	RPS6KA4 CDC42BPA CIT STK38L	1.60e-03	37	256	4	IPR017892
Domain	Cu-oxidase_3	HEPH HEPHL1	1.82e-03	5	256	2	IPR011707
Domain	Cu-oxidase_3	HEPH HEPHL1	1.82e-03	5	256	2	PF07732
Domain	MULTICOPPER_OXIDASE1	HEPH HEPHL1	1.82e-03	5	256	2	PS00079
Domain	Cu_oxidase_CS	HEPH HEPHL1	1.82e-03	5	256	2	IPR033138
Pathway	REACTOME_RAC1_GTPASE_CYCLE	DOCK4 NCF1 DOCK5 DOCK6 PREX1 MPP7 CDC42BPA KALRN TFRC NCF1C NCF1B	2.51e-05	175	190	11	MM15599
Pathway	REACTOME_RAC1_GTPASE_CYCLE	DOCK4 NCF1 DOCK5 DOCK6 PREX1 MPP7 DOCK3 CDC42BPA KALRN CIT TFRC	3.99e-05	184	190	11	M41809
Pathway	REACTOME_RHOG_GTPASE_CYCLE	DOCK4 DOCK5 PREX1 MPP7 DOCK3 KALRN TFRC	6.07e-05	74	190	7	M41814
Pathway	BIOCARTA_PDZS_PATHWAY	SPTBN1 ANK1 GRIN1 EPB41	8.44e-05	18	190	4	M22001
Pathway	REACTOME_RHO_GTPASE_CYCLE	DOCK4 STAM2 SPTBN1 NCF1 DOCK5 ABCD3 DOCK6 PREX1 MPP7 CDC42BPA KALRN TFRC CCT6A AKAP13 ARHGEF3 NCF1C NCF1B	9.39e-05	439	190	17	MM15595
Pathway	REACTOME_RHO_GTPASE_CYCLE	DOCK4 STAM2 SPTBN1 NCF1 DOCK5 ABCD3 DOCK6 PREX1 MPP7 DOCK3 CDC42BPA KALRN CIT TFRC CCT6A AKAP13 ARHGEF3	1.27e-04	450	190	17	M27078
Pathway	REACTOME_RAC2_GTPASE_CYCLE	DOCK4 NCF1 PREX1 MPP7 TFRC NCF1C NCF1B	1.70e-04	87	190	7	MM15600
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DOCK4 STAM2 SPTBN1 NCF1 LIN7B DOCK5 RAB9A ABCD3 DOCK6 PREX1 MPP7 CDC42BPA KALRN NUP98 TFRC CCT6A PPP2R5E AKAP13 ARHGEF3 NCF1C NCF1B	1.80e-04	649	190	21	MM15690
Pathway	REACTOME_CROSS_PRESENTATION_OF_PARTICULATE_EXOGENOUS_ANTIGENS_PHAGOSOMES	NCF1 NCF1C NCF1B	1.91e-04	9	190	3	MM14524
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 STAM2 EMC1 CD2AP SPTBN1 KDM3B PITPNC1 LYST FSIP2 BRAF DSTYK SYNE2 KMT2A DOCK6 DOP1B VCPIP1 ANKS1A CDC42BPA STK32C E2F8 GRIP1 VPS13D IPO9 SLC12A2 AKAP13 EDRF1 EPB41 DOP1A	9.92e-11	861	261	28	36931259
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	HIP1 MAGOH EMC1 CD2AP TEX10 TRRAP GREB1L DDX46 ABCD3 KMT2A FAM83D TRMT1L TASOR PREX1 MPP7 ARMC8 CDC42BPA GRWD1 CPSF6 MTHFD1L TEKT5 CIT METTL14 RIOX2 ACTR1A CCT6A PPP2R5E SLC12A2 BAZ1A MTHFD1 DROSHA CDYL2 INTS9 EXOC2 EDRF1 EPB41 GABPA	2.09e-10	1497	261	37	31527615
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	SPTBN1 AK9 TEX10 TRRAP DDB1 RYR3 DDX46 KIF19 KMT2A ANK1 ANK3 CPSF6 MTHFD1L COPS3 NUP214 CCDC57 VPS13D MTHFD1 MYOM2 ATM	1.52e-09	497	261	20	36774506
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	EPRS1 EMC1 MYO1D DNAJA2 SPTBN1 DDB1 RAB9A VPS33B ABCD3 DNAH5 MGAM2 MCOLN2 ARMC8 VRK1 GRWD1 CPSF6 MTHFD1L SMC6 NUP98 COPS3 NUP214 IDH3A CHORDC1 TFRC RIOX2 ACTR1A TARDBP CCT6A IPO9 BAZ1A MTHFD1 ATM TOP2B PCMT1	2.98e-09	1425	261	34	30948266
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	HIP1 ERAP1 DNAJA2 CD2AP SPTBN1 KDM3B DDB1 GMPS DDX46 SYNE2 CUL2 FLNC VRK1 DNAJC13 CPSF6 MTHFD1L NUP98 RNF213 COPS3 NUP214 IDH3A CHORDC1 TFRC MRPL39 ACTR1A TARDBP CCT6A IPO9 NUDT1 GSDMA DCXR EPB41 PCMT1	3.91e-09	1367	261	33	32687490
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	EMC1 ATP7B LYST VPS33B COG6 SYNE2 ABCD3 DOCK6 DOP1B DNAJC13 CDC42BPA TAPT1 VPS26B SLC26A2 VPS8 VPS13D SLC12A2 ATP4A USP33	1.13e-08	504	261	19	34432599
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	EPRS1 GLS2 MYO1A MYO1D SPTBN1 ANKS1B TEX10 LYST FER1L6 NUP54 SACS SYNE2 KMT2A RAB39B TASOR PREX1 RPGRIP1 FLNC NUP98 CCDC57 TFRC TARDBP CCT6A BAZ1A CIAO3 MYOM2 ATM POTEJ MAPK6 TOP2B GABPA DOP1A MYBPC2	1.42e-08	1442	261	33	35575683
Pubmed	Activation of neuronal NMDA receptors induces superoxide-mediated oxidative stress in neighboring neurons and astrocytes.	NCF1 GRIN1 NCF1C NCF1B	1.54e-08	5	261	4	22973021
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	EPRS1 EMC1 MYO1D TEX10 TRRAP DDB1 NUP54 DDX46 RAB9A SACS SYNE2 ABCD3 FLNC CPSF6 NUP98 NUP214 IDH3A CIT TFRC TARDBP CCT6A SLC12A2 BAZ1A MTHFD1 MMAB TOP2B PCMT1	1.90e-08	1024	261	27	24711643
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	EPRS1 IFT172 DNAJA2 SPTBN1 DDB1 GMPS DDX46 ABCD3 TRMT1L CUL4B DNAJC13 GRWD1 NUP98 NUP214 IDH3A TFRC ACTR1A CCT6A IPO9 MTHFD1 TOP2B	1.97e-08	638	261	21	33239621
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	DOCK4 EPRS1 MAGOH EMC1 MYO1D TRRAP FANCC TTBK1 BRAF DSTYK ABCD3 STK24 PREX1 ANKS1A CUL2 CPSF6 MTHFD1L NUP98 COPS3 LRRK1 BCAS1 AZIN1 IPO9 NUDT1 MTHFD1 SHCBP1 AKAP13 STK38L EPB41 PCMT1	4.35e-08	1284	261	30	17353931
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	KCTD9 DNAJA2 KDM3B TEX10 TRRAP DDB1 GMPS DDX46 KMT2A TRMT1L CUL4B CUL2 VRK1 SMC6 NUP98 RNF213 METTL14 TFRC POLR3C TARDBP CCT6A BAZ1A ATM MYO15A TOP2B PCMT1	6.13e-08	1014	261	26	32416067
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	GLS2 ERAP1 PBLD TEX10 DDB1 PHKA1 ABCD3 FLNC ANK3 KALRN SMC6 RNF213 IPO9 GSDMA	8.96e-08	304	261	14	32235678
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	STAM2 TRRAP BIRC6 DDB1 KMT2A TRMT1L TASOR ARMC8 ANKS1A CUL4B RPGRIP1L CPSF6 NUP98 NUP214 CCT6A BAZ1A TOP2B	1.19e-07	469	261	17	27634302
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	2.12e-07	8	261	4	12634303
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	DOCK4 ILDR2 SPTBN1 ADGRB2 ANKS1B DOCK3 CDC42BPA ANK3 GRIN1 CIT IL1RAPL1	3.30e-07	197	261	11	36604605
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	NBEAL1 CD2AP SPTBN1 VPS33B SYNE2 ABCD3 VCPIP1 CUL4B FLNC TAPT1 NUP98 NUP214 CHORDC1 VPS13D SLC12A2 EPB41 USP33 ALG13	3.64e-07	568	261	18	37774976
Pubmed	NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	18787174
Pubmed	Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	24873968
Pubmed	Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	20142487
Pubmed	p47(phox) contributes to albuminuria and kidney fibrosis in mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	25565313
Pubmed	Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	39357591
Pubmed	Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	11435342
Pubmed	Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	16041040
Pubmed	Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	17307863
Pubmed	Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	27829407
Pubmed	The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	22376231
Pubmed	Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	12364355
Pubmed	P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	10670582
Pubmed	Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	26528554
Pubmed	The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	19052348
Pubmed	Effect of early particulate air pollution exposure on obesity in mice: role of p47phox.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	20864666
Pubmed	Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	17114280
Pubmed	Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	17332431
Pubmed	Lpp of Escherichia coli K1 inhibits host ROS production to counteract neutrophil-mediated elimination.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	36592568
Pubmed	Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	30504842
Pubmed	Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	33705493
Pubmed	Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	15513930
Pubmed	Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	15033459
Pubmed	p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	20817944
Pubmed	Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	23024271
Pubmed	Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	15310853
Pubmed	Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	34970267
Pubmed	Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	25689796
Pubmed	Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	14993144
Pubmed	The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	12031896
Pubmed	Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	15936744
Pubmed	NADPH oxidase p47phox siRNA attenuates adventitial fibroblasts proliferation and migration in apoE(-/-) mouse.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	25628043
Pubmed	Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	12560337
Pubmed	Inhibition of endothelial Nox2 activation by LMH001 protects mice from angiotensin II-induced vascular oxidative stress, hypertension and aortic aneurysm.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	35276443
Pubmed	Reactive oxygen species modulate growth of cerebral aneurysms: a study using the free radical scavenger edaravone and p47phox(-/-) mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	19381132
Pubmed	Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: decreased autoimmune encephalomyelitis in nicotinamide adenine dinucleotide phosphate oxidase knockout mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	10799876
Pubmed	Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	11834706
Pubmed	Virulence and cellular interactions of Burkholderia multivorans in chronic granulomatous disease.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	19635825
Pubmed	The NCF1 variant p.R90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	35788118
Pubmed	Hydrophobic bile salts induce hepatocyte shrinkage via NADPH oxidase activation.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	17310103
Pubmed	Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	24358335
Pubmed	Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	10891396
Pubmed	NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	26209274
Pubmed	NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	11018074
Pubmed	Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	9116268
Pubmed	Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	20686129
Pubmed	Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	21570954
Pubmed	Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	23482812
Pubmed	The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	10085000
Pubmed	Methamphetamine alters occludin expression via NADPH oxidase-induced oxidative insult and intact caveolae.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	21435178
Pubmed	Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	29228045
Pubmed	Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	22155727
Pubmed	Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	24576409
Pubmed	The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	26645958
Pubmed	NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	24549323
Pubmed	Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	19168575
Pubmed	A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	27798190
Pubmed	Conditional haploinsufficiency of NCF1 (encoding p47(phox)), a signaling gene with a heterozygous phenotype potentially subject to natural selection.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	15626477
Pubmed	Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	22319452
Pubmed	Endosomal acidification and activation of NADPH oxidase isoforms are upstream events in hyperosmolarity-induced hepatocyte apoptosis.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	16772302
Pubmed	Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	32504071
Pubmed	Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	16280459
Pubmed	NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenation.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	17220182
Pubmed	The p47phox mouse knock-out model of chronic granulomatous disease.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	7650482
Pubmed	Disseminated trichosporonosis in a murine model of chronic granulomatous disease.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	12868577
Pubmed	NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	20859296
Pubmed	Loss of NADPH oxidase-derived superoxide skews macrophage phenotypes to delay type 1 diabetes.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	25288672
Pubmed	Lack of reactive oxygen species breaks T cell tolerance to collagen type II and allows development of arthritis in mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	17641008
Pubmed	Hyperoxia impairs postnatal alveolar epithelial development via NADPH oxidase in newborn mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	19411313
Pubmed	Critical role for p47phox in renin-angiotensin system activation and blood pressure regulation.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	16843452
Pubmed	A glucose-6-phosphate isomerase peptide induces T and B cell-dependent chronic arthritis in C57BL/10 mice: arthritis without reactive oxygen species and complement.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	23911657
Pubmed	Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	27044504
Pubmed	p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	22184329
Pubmed	Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	33545139
Pubmed	Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	31118934
Pubmed	Intermittent hypoxia has organ-specific effects on oxidative stress.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	18703411
Pubmed	Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	23918780
Pubmed	NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	28274989
Pubmed	NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	34557202
Pubmed	Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	28467721
Pubmed	Reactive oxygen species delay control of lymphocytic choriomeningitis virus.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	23328631
Pubmed	p47phox-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	34572995
Pubmed	B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	25989352
Pubmed	Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.	NCF1 NCF1C NCF1B	4.18e-07	3	261	3	17404617
GeneFamily	Ankyrin repeat domain containing	CDKN2D GLS2 ANKS1B ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD2 CASKIN1 ANKRD12 ANKRD20A1 ANKS1A SLF1 ANK1 ANK3 POTEG POTEM POTEJ TNKS2 GABPB1	1.98e-12	242	173	19	403
GeneFamily	Myosins, class I	MYO1G MYO1A MYO1D	4.65e-05	8	173	3	1097
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEG POTEM POTEJ	2.29e-04	13	173	3	685
GeneFamily	PDZ domain containing	IL16 LIN7B PTPN4 PREX1 MPP7 GRIP1 GRIP2	6.57e-04	152	173	7	1220
GeneFamily	Tektins	TEKT1 TEKT5	8.93e-04	5	173	2	949
GeneFamily	Endogenous ligands\|Minor histocompatibility antigens	MYO1G ERAP1 MTHFD1 AKAP13	1.43e-03	51	173	4	870
GeneFamily	Fibronectin type III domain containing\|I-set domain containing\|Myosin binding proteins	MYOM2 MYBPC2	2.45e-03	8	173	2	658
GeneFamily	Cullins	CUL4B CUL2	2.45e-03	8	173	2	1032
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 LYST	3.14e-03	9	173	2	1230
GeneFamily	Nucleoporins	NUP54 NUP98 NUP214	3.48e-03	32	173	3	1051
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PREX1 KALRN AKAP13 ARHGEF3	3.68e-03	66	173	4	722
Coexpression	GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN	PIGN EPRS1 TXK TASOR MPP7 ANKS1A CUL4B DNAJC13 WDR19 RIOX2 DROSHA EXOC2 USP33	9.97e-08	197	261	13	M8271
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	DOCK4 CD2AP KDM3B TRRAP GMPS PTPN4 BRCA2 SACS SYNE2 TASOR STK24 DOP1B ANKS1A CUL2 VRK1 DNAJC13 TUT4 CDC42BPA NUP98 AZIN1 PPP2R5E BAZ1A AKAP13 N4BP1 MAPK6 PCMT1	5.16e-07	856	261	26	M4500
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	ZNF131 EPRS1 STAM2 HIP1 ERAP1 SPTBN1 KDM3B TEX10 NME8 RYR3 SACS SYNE2 KMT2A TOR1B TASOR CA8 CUL4B DNAJC13 RPS6KA4 NUP98 TMBIM6 POLR3C RIOX2 CCT6A PPP2R5E BAZ1A MTRR N4BP1 ATM EDRF1 PCMT1 ALG13	5.60e-07	1215	261	32	M41122
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	EPRS1 NAP1L3 DDX46 SACS COG6 SYNE2 TASOR CUL4B CUL2 VRK1 DNAJC13 TUT4 SLF1 CDC42BPA SMC6 CHORDC1 BAZ1A ATM MAPK6 TOP2B	1.06e-05	656	261	20	M18979
Coexpression	LEE_BMP2_TARGETS_DN	ZNF131 DNAJA2 NUP54 GMPS KLHL29 BMP2 SACS VRK1 SLF1 GRWD1 CPSF6 MTHFD1L IDH3A CHORDC1 E2F8 TFRC AZIN1 TARDBP CCT6A BAZ1A MTHFD1 MTRR MAPK6 PCMT1	1.40e-05	904	261	24	M2325
Coexpression	LEE_BMP2_TARGETS_DN	ZNF131 DNAJA2 NUP54 GMPS KLHL29 BMP2 SACS VRK1 SLF1 GRWD1 CPSF6 MTHFD1L IDH3A CHORDC1 E2F8 TFRC AZIN1 TARDBP CCT6A BAZ1A MTHFD1 MTRR MAPK6 PCMT1	1.92e-05	922	261	24	MM1068
Coexpression	PGF_UP.V1_UP	STAM2 MAGOH CD2AP NAP1L3 BPGM SACS SYNE2 TASOR MAPK6 STK38L	2.23e-05	190	261	10	M2674
Coexpression	NAKAYA_B_CELL_FLUMIST_AGE_18_50YO_7DY_UP	ZNF131 IL16 MAGOH ARL5A RAB9A BRCA2 ANKRD12 ARMC8 ANK3 CPSF6 RIOX2 PPP2R5E CNTNAP2 INTS9 ATM PCMT1	2.52e-05	475	261	16	M40979
Coexpression	NAKAYA_MONOCYTE_FLUMIST_AGE_18_50YO_7DY_UP	EPRS1 STAM2 HIP1 KDM3B TRRAP LYST RAB9A TASOR ARMC8 ANKS1A BAZ1A MTRR AKAP13 ATM STK38L ALG13	2.65e-05	477	261	16	M40930
Coexpression	PUJANA_CHEK2_PCC_NETWORK	ZNF131 MAGOH MYO1A CD2AP GMPS DDX46 BRCA2 FAM76A STK24 VRK1 CPSF6 COPS3 TFRC POLR3C TARDBP PPP2R5E BAZ1A NUDT1 ATM EPB41 PCMT1	2.80e-05	761	261	21	M11961
Coexpression	GSE3982_MAC_VS_NEUTROPHIL_UP	MYO1D ERAP1 RAB9A FAM76A DOP1B CUL2 MEAK7 RIOX2 ARHGEF3 PCMT1	3.18e-05	198	261	10	M5491
Coexpression	HALLMARK_MITOTIC_SPINDLE	DOCK4 CD2AP SPTBN1 BRCA2 PREX1 CDC42BPA AKAP13 ARHGEF3 STK38L EPB41	3.32e-05	199	261	10	M5893
Coexpression	GSE40685_NAIVE_CD4_TCELL_VS_FOXP3_KO_TREG_PRECURSOR_UP	MYO1G ARL5A NUP54 BRCA2 LRRK1 RIOX2 ACTR1A TARDBP N4BP1 PCMT1	3.46e-05	200	261	10	M9304
Coexpression	GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_UP	CDKN2D SPTBN1 ARL5A HEPH SACS COG6 FLT3LG SKOR1 CD151 N4BP1	3.46e-05	200	261	10	M9317
Coexpression	GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP	CD2AP NCF1 ZNF280B TEX10 SMC6 TFRC TARDBP DROSHA MTRR ARHGEF3	3.46e-05	200	261	10	M5602
Coexpression	DESCARTES_ORGANOGENESIS_PRIMITIVE_ERYTHROID_LINEAGE	KCTD9 ANKRD20A3P ANKRD20A8P BPGM ANKRD20A4P BRCA2 ANKRD20A1 AKAP7 FLT3LG ANK1 SLC26A2 CIT TFRC AZIN1 MYO15A EPB41	4.34e-05	497	261	16	MM3640
Coexpression	ERWIN_COHEN_BLOOD_LIVE_VACCINE_TC_83_AGE_23_48YO_VACCINATED_VS_CONTROL_14DY_UP	ERAP1 CD2AP ARL5A NUP54 SACS COG6 ABCD3 TASOR AKAP7 ANK3 CPSF6 CHORDC1 TFRC RIOX2 ATM ARHGEF3 EDRF1 PCMT1 ALG13	6.59e-05	687	261	19	M41022
Coexpression	BLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_INFECTION_UP	NBEAL1 HEPHL1 DHX58 NR1D1 TFRC POSTN THBS1 CDYL2	7.18e-05	137	261	8	M34024
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	DOCK4 MYO1D NBEAL1 SPTBN1 ANKRD12 CDC42BPA KALRN IL1RAPL1 POSTN	7.49e-05	177	261	9	M39245
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	CD2AP TRRAP GMPS TASOR STK24 DOP1B ANKS1A DNAJC13 TUT4 CDC42BPA NUP98 PPP2R5E BAZ1A MAPK6 PCMT1	7.53e-05	466	261	15	M13522
Coexpression	MURARO_PANCREAS_DUCTAL_CELL	EPRS1 SERPINA3 HIP1 MAOB CD2AP SPTBN1 AGPAT3 BMP2 RAB9A BPGM SYNE2 SYPL1 STK24 AKAP7 ANK3 SLC34A2 RNF213 TMBIM6 TFRC THBS1 SLC12A2 BAZ1A AKAP13 CD151 MAPK6 STK38L TOP2B CD276	8.08e-05	1276	261	28	M39173
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	MYO1G IL16 ERAP1 PITPNC1 BIRC6 LYST JAK3 PTPN4 SACS DSTYK KMT2A TASOR STK24 PREX1 FLT3LG TUT4 SLF1 EMB SLC26A2 NUP98 RNF213 NLRP1 AZIN1 PPP2R5E BAZ1A AKAP13 N4BP1 ATM ARHGEF3 TOP2B GABPA	9.00e-05	1492	261	31	M40023
Coexpression	GEORGES_TARGETS_OF_MIR192_AND_MIR215	CDKN2D EMC1 ZNF165 SPTBN1 PITPNC1 BRCA2 DSTYK FAM83D TOR1B AKAP7 CA8 RPGRIP1L SLF1 EMB CPSF6 SLC26A2 RADX CIT E2F8 TARDBP MMAB EDRF1	9.49e-05	892	261	22	M18120
Coexpression	GAVIN_PDE3B_TARGETS	NCF1 SYPL1 NCF1C NCF1B	1.03e-04	25	261	4	MM726
Coexpression	GSE2706_UNSTIM_VS_2H_R848_DC_DN	MYO1G MCOLN2 CASQ2 DGCR6L DENND3 BAZ1A MAPK6 NCF1C ALG13	1.51e-04	194	261	9	M4692
Coexpression	DIAZ_CHRONIC_MYELOGENOUS_LEUKEMIA_UP	PIGN MAGOH ATP7B DNAJA2 CD2AP KDM3B DDB1 ARL5A NUP54 RAB9A VPS33B ABCD3 STK24 CUL4B CDC42BPA CPSF6 NUP98 COPS3 TFRC AZIN1 ACTR1A TARDBP CCT6A PPP2R5E BAZ1A MTHFD1 ARHGEF3 EPB41 PCMT1	1.60e-04	1399	261	29	M535
Coexpression	BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A	NPL DOCK4 ILDR2 KCTD9 SERPINA3 ANKRD20A3P ANKRD20A8P DOCK5 JAK3 MYO3A ANKRD20A4P BRCA2 ANKRD2 SYNE2 DOCK6 ANKRD20A1 MCOLN2 FLNC RPS6KA4 GSDMA ARHGEF3 MAPK6	1.71e-04	930	261	22	MM893
Coexpression	GSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_UP	HS6ST2 NAP1L3 GMPS JAK3 VPS33B NOVA1 ANKS1A BCAS1 CNTNAP2	1.75e-04	198	261	9	M9386
Coexpression	GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_UP	HIP1 EMC1 ERAP1 DOCK5 GRWD1 COPS3 E2F8 WDR19 N4BP1	1.82e-04	199	261	9	M8002
Coexpression	GSE42724_MEMORY_BCELL_VS_PLASMABLAST_UP	RAB9A KMT2A DOP1B DHX58 DENND3 POLR3C MAPK6 EPB41 GABPB1	1.82e-04	199	261	9	M9786
Coexpression	GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_UP	FANCC STK24 CA8 NUDT1 MYOM2 MYO15A ATP4A EPB41 MYBPC2	1.82e-04	199	261	9	M5323
Coexpression	GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_UP	DOCK5 DSTYK TRMT1L DOP1B ANKS1A RNF213 ACTR1A THBS1 BAZ1A	1.89e-04	200	261	9	M9455
Coexpression	GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN	EPRS1 BRCA2 FLT3LG GRWD1 COPS3 MRPL39 CCT6A MTHFD1 SHCBP1	1.89e-04	200	261	9	M4531
Coexpression	GSE27786_NKCELL_VS_MONO_MAC_UP	ERAP1 TEX10 SACS PREX1 CDK10 MRPL39 CCT6A NUDT1 MTHFD1	1.89e-04	200	261	9	M4860
Coexpression	GSE17580_TREG_VS_TEFF_DN	CDKN2D SPTBN1 LYST TXK DOCK5 SYNE2 DOP1B EMB TNKS2	1.89e-04	200	261	9	M3671
Coexpression	GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_UP	EMC1 ADGRB2 NUP54 IDH3A POLR3C RIOX2 SEMA3D ARHGEF3 GABPB1	1.89e-04	200	261	9	M8860
Coexpression	GSE24210_IL35_TREATED_VS_UNTREATED_TCONV_CD4_TCELL_DN	KCTD9 NCF1 TEX10 FANCC FAM83D MCOLN2 ARHGEF3 PCMT1 USP33	1.89e-04	200	261	9	M7850
Coexpression	PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7	ZNF165 LYST BRCA2 SYNE2 RAB39B PREX1 CA8 KALRN MEAK7 E2F8 MTHFD1 COA1 AKAP13	2.01e-04	399	261	13	M2413
Coexpression	MITSIADES_RESPONSE_TO_APLIDIN_DN	EPRS1 SPTBN1 TRRAP GMPS DDX46 CDC42BPA TARDBP DROSHA SHCBP1 MAPK6	2.19e-04	250	261	10	M11318
Coexpression	CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP	CYP2C19 GLS2 DOCK5 ARMC8 IDO2 THBS1	2.22e-04	86	261	6	M19610
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_1000	DOCK4 ILDR2 NBEAL1 HS6ST2 CD2AP BIRC6 GREB1L GMPS BMP2 SYNE2 ANKRD12 CUL4B RNF213 PPP2R5E SLC12A2 ALG13	2.45e-08	233	255	16	gudmap_developingGonad_e12.5_ovary_k5_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#3	PIGN KCTD9 HIP1 HS6ST2 SPTBN1 BIRC6 DDB1 FAM83D VCPIP1 CUL2 CPSF6 VPS8 NUP98 IDH3A CHORDC1 TFRC AZIN1 RIOX2 MRPL39 TARDBP IPO9 MAPK6 GABPA ALG13	5.21e-06	708	255	24	Facebase_RNAseq_e8.5_Floor Plate_2500_K3
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_1000	DOCK4 HS6ST2 CD2AP BIRC6 GREB1L GMPS SYNE2 CUL4B RNF213 SLC12A2	6.73e-06	138	255	10	gudmap_developingGonad_e12.5_epididymis_k5_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5	ILDR2 EPRS1 HIP1 DDX46 BRCA2 NOVA1 FHOD3 CIT BAZ1A ATM GABPB1	3.82e-05	204	255	11	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	DOCK4 ILDR2 NBEAL1 HS6ST2 CD2AP SPTBN1 BIRC6 GREB1L GMPS BMP2 BRCA2 SACS SYNE2 ANKRD12 VCPIP1 DNAJC13 SMC6 RNF213 DMC1 PPP2R5E SLC12A2 ATM ALG13	6.71e-05	776	255	23	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	ILDR2 EPRS1 HIP1 BIRC6 GMPS PTPN4 DDX46 BRCA2 TRMT1L NOVA1 SMC6 FHOD3 CIT BAZ1A INTS9 ATM EPB41 GABPB1	8.34e-05	532	255	18	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_500	DOCK4 BIRC6 GREB1L GMPS BMP2 SYNE2 RNF213	1.14e-04	91	255	7	gudmap_developingGonad_e12.5_ovary_k5_500
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	PITPNC1 JAK3 BRAF SYNE2 KMT2A ANKRD12 ANK3 RNF213 NLRP1 CHORDC1 TFRC ATM	1.65e-09	192	261	12	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	HIP1 MYO1D NBEAL1 ANKS1B RYR3 FAM83D MPP7 KALRN MTHFD1L SEMA3D STK38L	1.67e-08	189	261	11	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	SYNE2 KMT2A ANKRD12 MCOLN2 TUT4 SLF1 ANK3 EMB TARS3 EPB41	2.22e-08	151	261	10	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD2AP SPTBN1 BIRC6 LYST KMT2A TASOR TUT4 CCT6A THBS1 TOP2B	1.43e-07	184	261	10	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_C\|390C / Donor, Lineage, Cell class and subclass (all cells)	IL16 ANKRD20A2P TXK PTPN4 ANKRD20A4P ANKRD20A1 RNF213 MYOM2 ATM ARHGEF3	1.67e-07	187	261	10	1e8651e6c547384ace5a66b96c6b24a7f390a7ee
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_3\|Classical_Monocyte / Disease condition and Cell class	ZBTB37 KMT2A TOR1B FLT3LG POLR3C MRPL39 PPP2R5E EXOC2 EDRF1 DOP1A	1.84e-07	189	261	10	8b6f92ccfffc743c07201bc971b3dc1a6fa14ccc
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_3\|COVID-19_Convalescent / Disease condition and Cell class	ZBTB37 KMT2A TOR1B FLT3LG POLR3C MRPL39 PPP2R5E EXOC2 EDRF1 DOP1A	1.84e-07	189	261	10	732e8dcffcb634ca2968f9170c9c4b31dd5d4206
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP7B MAOB ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	2.13e-07	192	261	10	7ccdb977320d09f21e70e7718ead73eeb56d0c48
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP7B MAOB ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	2.13e-07	192	261	10	f206c015f091234e2c86dfa66926e97b2ea99690
ToppCell	PND28-Epithelial-Epithelial_Alveolar\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP7B MAOB ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	2.13e-07	192	261	10	69963e8dc6d6368243e61da133484eb23225625a
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP7B MAOB ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	2.13e-07	192	261	10	bfc68af68fdb99ddfe4add49671e4b4c26e6f962
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	CD2AP BPGM SYNE2 ANKRD12 CDC42BPA SLC26A2 BCAS1 THBS1 PPP2R5E BAZ1A	2.97e-07	199	261	10	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	ASK454-Immune-NK_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	HS6ST2 TXK PTPN4 ANKRD20A4P PREX1 BCAS1 CHORDC1 MYOM2 ATM	7.58e-07	170	261	9	84705434234bf2fbb5256bd5a1f6ab54c01c5a51
ToppCell	Epithelial-Epithelial-C_(AT2)\|Epithelial / shred on cell class and cell subclass (v4)	PBLD RAB9A ABCD3 AKAP7 CA8 ANK3 SLC34A2 SLC12A2 DCXR	8.77e-07	173	261	9	f57cbf5bd2a9e5db47b4919e9cd5e50781c1a990
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ILDR2 CDKN2D IL16 TXK PTPN4 PREX1 MYOM2 ATM EPB41	9.20e-07	174	261	9	7ebf06076946729c1af25109df6066731097c3b1
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ILDR2 CDKN2D IL16 TXK PTPN4 PREX1 MYOM2 ATM EPB41	9.20e-07	174	261	9	90961e8839514985712b8b986aec3391bb249ba7
ToppCell	5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ILDR2 CDKN2D IL16 TXK PTPN4 PREX1 MYOM2 ATM EPB41	9.20e-07	174	261	9	c4b0987d9394f977fe6bc6a4214a6d8d73d0abcc
ToppCell	wk_15-18-Hematologic-Meg-ery-Definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NPL CDKN2D BPGM ANKRD20A4P ANKRD20A1 CA8 ANK1 TFRC EPB41	1.34e-06	182	261	9	93841f730ca1a735eaaf5f2ccbe5c45ab0e029d1
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	HIP1 MYO1D NBEAL1 ANKS1B MPP7 KALRN MTHFD1L SEMA3D STK38L	1.40e-06	183	261	9	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GREB1L ANKRD2 DOCK3 FLNC CASQ2 FHOD3 IL1RAPL1 BCO2 MYOM2	1.46e-06	184	261	9	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NPL BPGM ANKRD20A4P FAM83D CA8 ANK1 CHORDC1 TFRC EPB41	1.53e-06	185	261	9	e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	MYO1D NBEAL1 ANKS1B RYR3 MPP7 KALRN MTHFD1L SEMA3D STK38L	1.75e-06	188	261	9	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCD3 CA8 ANK3 EMB SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	1.75e-06	188	261	9	562f5984efdbbcb8f53ddcee033ccbf9eb678425
ToppCell	IPF-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ILDR2 MYO1D ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1 MCOLN2 IDO2	1.75e-06	188	261	9	47bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCD3 CA8 ANK3 EMB SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	1.75e-06	188	261	9	7499e353ea5853d06558b20cedee3c7910425d7d
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PIGN SPTBN1 JAK3 SYNE2 PREX1 TUT4 ANK3 LRRK1 N4BP1	1.91e-06	190	261	9	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCD3 CA8 ANK3 SLC34A2 TMBIM6 TFRC SLC12A2 MTHFD1 DCXR	1.91e-06	190	261	9	ec1bd4929dc82bec2c983a31ece4e3aa82f3a2ab
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	ANKRD2 FLNC ANK3 CASQ2 FHOD3 IL1RAPL1 AKAP13 MYOM2 STK38L	1.91e-06	190	261	9	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	PND10-Epithelial-Epithelial_Alveolar\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCD3 CA8 ANK3 SLC34A2 TMBIM6 TFRC SLC12A2 MTHFD1 DCXR	1.91e-06	190	261	9	dc20d323cee2741e39fba597263d6418ae0eadaf
ToppCell	tumor_Lung-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	HIP1 GLS2 MYO1D ZNF165 DOCK5 MCOLN2 KALRN BCO2 MYBPC2	1.91e-06	190	261	9	58a6ab70737d719ca9725ac087f20dfe9be0463e
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BRCA2 FAM83D VRK1 SLF1 ANK1 EMB CIT E2F8 SHCBP1	1.99e-06	191	261	9	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYO1G IL16 NME8 TXK PTPN4 BPGM ANKRD20A4P MYOM2 GABPB1	2.08e-06	192	261	9	1922b0350d3375e67c314dbce8074e5cf986f2ef
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYO1G IL16 NME8 TXK PTPN4 BPGM ANKRD20A4P MYOM2 GABPB1	2.08e-06	192	261	9	a4d161e3d48bc020e687808b352325ef9d1cc1f3
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP7B ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	2.08e-06	192	261	9	4a46f7980ec145be5b4bf8b98265e3e0f2ea4c63
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYO1G IL16 NME8 TXK PTPN4 BPGM ANKRD20A4P MYOM2 GABPB1	2.08e-06	192	261	9	97c197643e59835c6d45dde9e549c9a1b1bb7288
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 NME8 HEPHL1 DOCK3 DPP10 C10orf67 MYO15A GPRIN2	2.31e-06	145	261	8	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	control-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MAGOH TXK JAK3 ANKRD12 FLT3LG DHX58 RNF213 NR1D1 N4BP1	2.36e-06	195	261	9	66959ae839eb60a573da06bdd227090ebb5bb9ed
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GHR SACS FAM83D DOCK3 KALRN CASQ2 FHOD3 SEMA3D MYOM2	2.46e-06	196	261	9	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TXK ZBTB37 SYNE2 KMT2A ANKRD12 ANK3 RNF213 ATM EPB41	2.57e-06	197	261	9	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	CD2AP DDX46 SYNE2 ANKRD12 DNAH5 CDC42BPA SLC26A2 PPP2R5E BAZ1A	2.79e-06	199	261	9	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TXK ZBTB37 BRAF SYNE2 ANKRD12 ANK3 RNF213 ATM EPB41	2.79e-06	199	261	9	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	mild-CD4+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SPTBN1 TXK SYNE2 KMT2A ANKRD12 FLT3LG ANK3 ATM EPB41	2.79e-06	199	261	9	3e4baaf4ee23f257d821194468102c00a8ad2f21
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PTPN4 SYNE2 KMT2A MCOLN2 EMB RNF213 N4BP1 ATM EPB41	2.91e-06	200	261	9	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2--L2-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PITPNC1 PHKA1 DPP10 ANK1 GRIP1 IL1RAPL1 POSTN CNTNAP2 GRIP2	2.91e-06	200	261	9	c65e6336725856c4b5f6aeba1cf86a23ec815d34
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	BRAF SYNE2 KMT2A ANKRD12 EMB RNF213 AKAP13 N4BP1 EPB41	2.91e-06	200	261	9	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PITPNC1 PHKA1 DPP10 ANK1 GRIP1 IL1RAPL1 POSTN CNTNAP2 GRIP2	2.91e-06	200	261	9	117a25b3b9cdbc2e198381350a8362bee25e82e7
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PITPNC1 PHKA1 DPP10 ANK1 GRIP1 IL1RAPL1 POSTN CNTNAP2 GRIP2	2.91e-06	200	261	9	d459e51507bf26865e6e7e04411379ec82a3edf8
ToppCell	P15-Epithelial-epithelial_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ATP7B CA8 ANK3 EMB SLC34A2 TFRC SLC12A2 DCXR	3.29e-06	152	261	8	00d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MYO1G CDKN2D SYPL1 KMT2A VPS8 MYOM2 USP33	3.67e-06	109	261	7	cc43c221487a712546917cc3253c158a1fc1fd7a
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MROH5 ABCD3 ANK3 SLC34A2 SLC12A2 MTHFD1 DCXR USP33	5.27e-06	162	261	8	d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MROH5 ABCD3 ANK3 SLC34A2 SLC12A2 MTHFD1 DCXR USP33	5.27e-06	162	261	8	06f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SPTBN1 JAK3 BRAF SYNE2 ANKRD12 ANK3 ATM EPB41	5.27e-06	162	261	8	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	P03-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ATP7B ABCD3 CA8 ANK3 EMB SLC34A2 TFRC DCXR	7.51e-06	170	261	8	3fd37e9b377d6485cea1262c31a8507d18a78514
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GREB1L ANKRD2 DOCK3 FLNC CASQ2 FHOD3 BCO2 MYOM2	7.51e-06	170	261	8	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	P15-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ATP7B CA8 ANK3 EMB SLC34A2 TFRC SLC12A2 DCXR	7.51e-06	170	261	8	6c0619cbe2f01a6de18da0a137f92bda0cbdf075
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ATP7B CA8 ANK3 EMB SLC34A2 CASQ2 TFRC DCXR	7.51e-06	170	261	8	d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCell	ASK454-Immune-NK_cell\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	HS6ST2 TXK PTPN4 ANKRD20A4P PREX1 BCAS1 CHORDC1 MYOM2	8.18e-06	172	261	8	c9e738c3540ee09b08805b1cdb66b4a0d9d40d33
ToppCell	P03-Epithelial-epithelial_progenitor_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ABCD3 CA8 ANK3 EMB SLC34A2 TFRC MTHFD1 DCXR	8.90e-06	174	261	8	23c7fdfc73170cfc5cdee5bb7fbee0c8bbbbca07
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL RYR3 COG6 DOCK3 MRC1 POSTN SEMA3D GSDMA	9.28e-06	175	261	8	09163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL RYR3 COG6 DOCK3 MRC1 POSTN SEMA3D GSDMA	9.28e-06	175	261	8	0801cccec6915aefc135262fc74580280fd51aa5
ToppCell	P03-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ABCD3 CA8 ANK3 EMB SLC34A2 TFRC MTHFD1 DCXR	9.28e-06	175	261	8	a6d9ca35d3c4b4e3889d0a69b514f63ae630da6b
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial-AT2\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ATP7B AGPAT3 ABCD3 CA8 ANK3 EMB SLC34A2 DCXR	9.67e-06	176	261	8	ac76f2cd6c63f30b38b89b58bad2baa4dde8ce3a
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 IFT172 BPIFB1 AK9 DNAH5 PCDHB1 C10orf67 CNTNAP2	9.67e-06	176	261	8	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	PIGN LYST DNAJC13 KALRN NUP98 RNF213 TFRC BCO2	1.01e-05	177	261	8	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GREB1L ANKRD2 DOCK3 FLNC CASQ2 FHOD3 BCO2 MYOM2	1.19e-05	181	261	8	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	SYNE2 ANKRD12 ANK3 RADX RNF213 CHORDC1 TFRC ATM	1.19e-05	181	261	8	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B2\|356C / Donor, Lineage, Cell class and subclass (all cells)	MYO1G NME8 TXK PTPN4 SYNE2 MYOM2 ATM ARHGEF3	1.23e-05	182	261	8	52baef8173df0a55307c375674a37c2488066738
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 PITPNC1 LYST TXK TASOR TUT4 CCT6A TOP2B	1.23e-05	182	261	8	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 PITPNC1 LYST TXK TASOR TUT4 CCT6A TOP2B	1.23e-05	182	261	8	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	HIP1 MYO1D NBEAL1 ANKS1B MPP7 KALRN MTHFD1L SEMA3D	1.28e-05	183	261	8	818fd886e0188091310825f9145fa53328f2c979
ToppCell	NS-critical-d_0-4-Lymphoid-Treg\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IL16 PITPNC1 PTPN4 SYNE2 KMT2A FLT3LG EMB ATM	1.28e-05	183	261	8	f478dfa231fc1b12ead0183cc9d22077cdf43d1f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 RYR3 DNAH5 ANK1 KALRN MROH2A MYOM2 MYO15A	1.34e-05	184	261	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 RYR3 DNAH5 ANK1 KALRN MROH2A MYOM2 MYO15A	1.34e-05	184	261	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	MYO1D ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1 MCOLN2 IDO2	1.34e-05	184	261	8	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	1.34e-05	184	261	8	49705c8fec565b16216bdf48e83e27521f52d99a
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ILDR2 ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1 MCOLN2 IDO2	1.34e-05	184	261	8	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 RYR3 DNAH5 ANK1 KALRN MROH2A MYOM2 MYO15A	1.34e-05	184	261	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GREB1L ANKRD2 DOCK3 FLNC CASQ2 FHOD3 IL1RAPL1 MYOM2	1.39e-05	185	261	8	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_reticulocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NPL CDKN2D BPGM FAM83D CA8 ANK1 TFRC EPB41	1.39e-05	185	261	8	4a2c85e292d4cbce80e92992ded5d66a3aa446ee
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NPL CDKN2D BPGM FAM83D CA8 ANK1 TFRC EPB41	1.39e-05	185	261	8	c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	1.39e-05	185	261	8	2adb32096aa3473f8d417e5ce9e65264beca9b52
ToppCell	IPF-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ILDR2 ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1 MCOLN2 IDO2	1.44e-05	186	261	8	962c2dada19185628ead77c32fcb07fa95114247
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 CD2AP SPTBN1 LYST SACS SYNE2 DOCK6 CCT6A	1.44e-05	186	261	8	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PITPNC1 TXK PTPN4 SYNE2 FLT3LG ANK3 ATM ARHGEF3	1.44e-05	186	261	8	c793a3d5709ad504c12fc3b2337746d90236d3ca
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	STAM2 NBEAL1 BIRC6 DDX46 ANKRD12 TRMT1L VPS13D GABPA	1.44e-05	186	261	8	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	IPF-Myeloid-cDC1\|IPF / Disease state, Lineage and Cell class	ILDR2 ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1 MCOLN2 IDO2	1.56e-05	188	261	8	2331a2bae1383820d598e93aa86c75b101069bac
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NPL CDKN2D BPGM FAM83D CA8 ANK1 TFRC EPB41	1.62e-05	189	261	8	1900e574870fc647bfa11c732a72f3d38aab717c
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ANKRD2 FLNC ANK3 CASQ2 FHOD3 IL1RAPL1 AKAP13 MYOM2	1.62e-05	189	261	8	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PITPNC1 TXK PTPN4 SYNE2 FLT3LG ANK3 ATM ARHGEF3	1.62e-05	189	261	8	5a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCell	PND10-Epithelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCD3 CA8 ANK3 EMB SLC34A2 SLC12A2 MTHFD1 DCXR	1.62e-05	189	261	8	89349e226a5512833a94b1bf68056a6985fe4afd
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	1.68e-05	190	261	8	8ff8c586237cf15f930416710bcff45205fe6f70
ToppCell	PND14-Epithelial\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	1.68e-05	190	261	8	f1eeef8f201bf7b96c020c8ab53dd7e05b3060ea
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAB9A ABCD3 CA8 ANK3 SLC34A2 TFRC AZIN1 DCXR	1.75e-05	191	261	8	f896fb490c4a17adac5e00ed9b6e6145eab1e564
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP7B ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 DCXR	1.75e-05	191	261	8	210589095a3f5d5117174caf6ec110b502f27030
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	1.75e-05	191	261	8	2f71f1fb6b5872d84860840b22e789a87ab14eec
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	MYO1D ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1 MCOLN2 IDO2	1.75e-05	191	261	8	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	COVID-19-T_cells\|COVID-19 / group, cell type (main and fine annotations)	PITPNC1 TXK JAK3 SYNE2 MCOLN2 ANK3 EMB EPB41	1.75e-05	191	261	8	7f64add931b64b8d35836fa6bee9ebab593844d3
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 MTHFD1 DCXR	1.75e-05	191	261	8	4ab3056f9af2a6caed39f32288562f480811cd7b
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP7B ABCD3 CA8 ANK3 SLC34A2 TFRC SLC12A2 DCXR	1.75e-05	191	261	8	f98fc372e579ce69409afbbe0f83c03c7ea62632
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAB9A ABCD3 CA8 ANK3 SLC34A2 TFRC AZIN1 DCXR	1.75e-05	191	261	8	08b1d3b3be78bf7fd9e9039027e35275f2be88d0
Disease	chronic granulomatous disease (implicated_via_orthology)	NCF1 NCF1C NCF1B	5.72e-06	5	247	3	DOID:3265 (implicated_via_orthology)
Disease	reticulocyte count	MYO1G EPRS1 DGCR6 GLS2 MYO1D CD2AP BIRC6 GREB1L DOCK5 BPGM DSTYK SYNE2 ANK1 COPS3 DGCR6L DENND3 TFRC RANBP3L BAZ1A ARHGEF3 MMAB EPB41	7.58e-05	1045	247	22	EFO_0007986
Disease	cerebral cavernous malformation (implicated_via_orthology)	STK24 CDC42BPA RNF213	9.10e-05	11	247	3	DOID:0060669 (implicated_via_orthology)
Disease	Epileptic encephalopathy	RYR3 NUP214 GRIN1 ALG13	1.11e-04	30	247	4	C0543888
Disease	acute myeloid leukemia (implicated_via_orthology)	KMT2A NUP98 TOP2B	1.21e-04	12	247	3	DOID:9119 (implicated_via_orthology)
Disease	rheumatoid arthritis (implicated_via_orthology)	NCF1 NCF1C NCF1B	1.21e-04	12	247	3	DOID:7148 (implicated_via_orthology)
Disease	visual epilepsy (implicated_via_orthology)	KDM3B CIT SLC12A2 CNTNAP2	1.82e-04	34	247	4	DOID:11832 (implicated_via_orthology)
Disease	ciliopathy (implicated_via_orthology)	TEKT1 RPGRIP1 RPGRIP1L WDR19	3.46e-04	40	247	4	DOID:0060340 (implicated_via_orthology)
Disease	pancreatic cancer (is_implicated_in)	FANCC BRAF BRCA2 THBS1 MTRR ATM	3.70e-04	112	247	6	DOID:1793 (is_implicated_in)
Disease	nucleotide measurement	ANKS1B SYNE2 SMC6 DOLK STK32C	3.73e-04	73	247	5	EFO_0010513
Disease	Neural tube defects, folate-sensitive	MTHFD1 MTRR	4.14e-04	4	247	2	cv:C1866558
Disease	anencephaly (is_implicated_in)	RPGRIP1L MTRR	4.14e-04	4	247	2	DOID:0060668 (is_implicated_in)
Disease	Neural tube defect, folate-sensitive	MTHFD1 MTRR	4.14e-04	4	247	2	C1866558
Disease	NEURAL TUBE DEFECTS, FOLATE-SENSITIVE	MTHFD1 MTRR	4.14e-04	4	247	2	601634
Disease	prostate cancer (biomarker_via_orthology)	BRCA2 THBS1	4.14e-04	4	247	2	DOID:10283 (biomarker_via_orthology)
Disease	mean corpuscular hemoglobin concentration	CDKN2D ZNF131 ATP7B GLS2 KLHL29 ANKRD12 PREX1 AKAP7 DNAJC13 ANK1 KALRN MEAK7 E2F8 TFRC BAZ1A COA1 AKAP13 EXOC2 MYO15A MMAB EPB41	4.37e-04	1105	247	21	EFO_0004528
Disease	Parkinson's disease (is_implicated_in)	MAOB DNAJC13 TARDBP MTRR ATM	4.49e-04	76	247	5	DOID:14330 (is_implicated_in)
Disease	Colorectal Neoplasms	ATP7B ABCA13 BMP2 BRAF ABCD3 FLNC TFRC POSTN MTRR	5.82e-04	277	247	9	C0009404
Disease	Adenocarcinoma of prostate	BRAF BRCA2 ATM	5.95e-04	20	247	3	C0007112
Disease	reticulocyte measurement	DGCR6 GLS2 MYO1D BIRC6 DOCK5 BPGM SYNE2 PREX1 ANK1 DGCR6L DENND3 TFRC AZIN1 SLC12A2 RANBP3L BAZ1A AKAP13 ARHGEF3 MMAB EPB41	6.02e-04	1053	247	20	EFO_0010700
Disease	proline measurement, amino acid measurement	DGCR6 DGCR6L	6.86e-04	5	247	2	EFO_0005134, EFO_0009773
Disease	Malignant neoplasm of prostate	SERPINA3 IL16 CYP2C19 ATP7B GHR BRAF BRCA2 KMT2A BCAS1 SLC12A2 AKAP13 ATM DCXR CD276	7.53e-04	616	247	14	C0376358
Disease	Prostatic Neoplasms	SERPINA3 IL16 CYP2C19 ATP7B GHR BRAF BRCA2 KMT2A BCAS1 SLC12A2 AKAP13 ATM DCXR CD276	7.53e-04	616	247	14	C0033578
Disease	Alzheimer disease	CD2AP NME8 BMP2 SYPL1 STK24 MRC1 ANK3 MTHFD1L DENND3 MRPL39 CNTNAP2 MYO15A	8.64e-04	485	247	12	MONDO_0004975
Disease	Colorectal Carcinoma	ATP7B ABCA13 BMP2 BRAF SACS ABCD3 FLNC KALRN MTHFD1L STK32C TFRC POSTN MTRR EDRF1 GABPB1	9.18e-04	702	247	15	C0009402
Disease	cortical surface area measurement	ILDR2 GLS2 NBEAL1 SPTBN1 KLHL29 BMP2 BPGM DSTYK NOVA1 ANKS1A DNAJC13 ANK3 CPSF6 DENND3 GRIP1 ACTR1A SEMA3D THBS1 PPP2R5E COA1 EXOC2 MAPK6 PCMT1	9.93e-04	1345	247	23	EFO_0010736
Disease	obsolete_red blood cell distribution width	CDKN2D MYO1A MYO1D RC3H1 CD2AP AK9 BIRC6 DOCK5 RAB9A VPS33B DSTYK SYNE2 ANKRD12 DOCK6 DNAJC13 ANK1 KALRN BCAS1 CIT TFRC SLC12A2 AKAP13 MMAB	1.01e-03	1347	247	23	EFO_0005192
Disease	spina bifida (is_implicated_in)	MTHFD1 MTRR	1.02e-03	6	247	2	DOID:0080016 (is_implicated_in)
Disease	Bare Lymphocyte Syndrome	JAK3 TFRC	1.02e-03	6	247	2	C0242583
Disease	glutathione peroxidase 7 measurement	TUT4 ARHGEF3	1.02e-03	6	247	2	EFO_0801635
Disease	mean platelet volume	GLS2 ERAP1 CD2AP SPTBN1 TXK KLHL29 DOCK5 DSTYK SYNE2 TASOR ANKS1A KALRN BCAS1 MEAK7 AZIN1 CD151 ARHGEF3 STK38L MMAB	1.03e-03	1020	247	19	EFO_0004584
Disease	leukemia	FANCC BRAF KMT2A ATM	1.17e-03	55	247	4	C0023418
Disease	unipolar depression, depressive symptom measurement	KMT2A PREX1 ZKSCAN2	1.31e-03	26	247	3	EFO_0003761, EFO_0007006
Disease	disease of cellular proliferation (implicated_via_orthology)	JAK3 ATM	1.43e-03	7	247	2	DOID:14566 (implicated_via_orthology)
Disease	infertility (implicated_via_orthology)	BRCA2 ATM	1.43e-03	7	247	2	DOID:5223 (implicated_via_orthology)
Disease	adverse effect, response to xenobiotic stimulus	GLS2 AGPAT3 DPP10 FHOD3	1.52e-03	59	247	4	EFO_0009658, GO_0009410
Disease	Autistic Disorder	DOCK4 MAOB MYO1D TRRAP GHR RAB39B IL1RAPL1 CNTNAP2	1.68e-03	261	247	8	C0004352
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	JAK3 KMT2A NUP214 MTRR	1.72e-03	61	247	4	C1961102
Disease	neuroimaging measurement	NBEAL1 SPTBN1 BMP2 PTPN4 BPGM DSTYK ANKS1A MRC1 CDC42BPA ANK3 MEAK7 DENND3 TFRC ACTR1A SEMA3D THBS1 BAZ1A EXOC2 MAPK6	1.77e-03	1069	247	19	EFO_0004346
Disease	leprosy	ANKS1B RPGRIP1L RPS6KA4 KALRN ACTR1A	1.77e-03	103	247	5	EFO_0001054
Disease	Strabismus	DNAH5 RPGRIP1 EXOC2	1.80e-03	29	247	3	HP_0000486
Disease	neural tube defect (is_implicated_in)	MTHFD1L MTHFD1	1.89e-03	8	247	2	DOID:0080074 (is_implicated_in)
Disease	twisted gastrulation protein homolog 1 measurement	ANKRD12 ARHGEF3	1.89e-03	8	247	2	EFO_0803205
Disease	Unilateral agenesis of kidney	GREB1L DSTYK	1.89e-03	8	247	2	C0266294
Disease	N-acetylneuraminate measurement	NPL ARHGEF3	1.89e-03	8	247	2	EFO_0020022
Disease	Acute erythroleukemia - M6a subtype	KMT2A NUP98	1.89e-03	8	247	2	C2930975
Disease	Acute myeloid leukemia FAB-M6	KMT2A NUP98	1.89e-03	8	247	2	C2930976
Disease	Acute erythroleukemia - M6b subtype	KMT2A NUP98	1.89e-03	8	247	2	C2930977
Disease	Acute erythroleukemia	KMT2A NUP98	1.89e-03	8	247	2	C2930974
Disease	intellectual disability (is_implicated_in)	RPGRIP1L IL1RAPL1 CNTNAP2	1.99e-03	30	247	3	DOID:1059 (is_implicated_in)
Disease	hair colour measurement	IL16 LYST DSTYK SYNE2 AKAP7 CDC42BPA EMB MROH2A BCAS1 TEKT5 CDK10 AKAP13 EXOC2	2.18e-03	615	247	13	EFO_0007822
Disease	Epilepsy	PIGH RAB39B SLC12A2 CNTNAP2 ALG13	2.27e-03	109	247	5	C0014544
Disease	Mental Retardation, X-Linked 1	RAB39B IL1RAPL1 ALG13	2.40e-03	32	247	3	C2931498
Disease	X-17653 measurement	CYP2C19 HEATR4	2.42e-03	9	247	2	EFO_0800783
Disease	Nephronophthisis	IFT172 RPGRIP1L	2.42e-03	9	247	2	cv:C0687120
Disease	Tendinopathy	MPP7 CNTNAP2	2.42e-03	9	247	2	EFO_1001434
Disease	colon carcinoma (is_implicated_in)	BRAF FLT3LG	2.42e-03	9	247	2	DOID:1520 (is_implicated_in)
Disease	myeloid white cell count	MYO1G RC3H1 SPTBN1 KLHL29 BPGM DSTYK PREX1 DNAJC13 CDC42BPA VPS8 LRRK1 CIT MEAK7 ACTR1A GSDMA ARHGEF3 TNKS2	2.47e-03	937	247	17	EFO_0007988
Disease	longevity	GLS2 RC3H1 BRAF VPS33B STK24 PREX1 KALRN MTHFD1	2.84e-03	284	247	8	EFO_0004300
Disease	Fanconi anemia (is_implicated_in)	FANCC BRCA2	3.00e-03	10	247	2	DOID:13636 (is_implicated_in)
Disease	neutrophil count	MYO1G ILDR2 IL37 GDAP2 RC3H1 SPTBN1 DSTYK DOCK6 PREX1 VRK1 DNAJC13 CDC42BPA EMB CIT MEAK7 AZIN1 ACTR1A GSDMA AKAP13 TNKS2 STK38L GABPB1	3.08e-03	1382	247	22	EFO_0004833
Disease	immature platelet measurement	MYO1G CD2AP DOCK3 KALRN ARHGEF3	3.32e-03	119	247	5	EFO_0803541
Disease	T-cell acute lymphoblastic leukemia (is_implicated_in)	JAK3 NUP98	3.65e-03	11	247	2	DOID:5603 (is_implicated_in)
Disease	Jeune thoracic dystrophy	IFT172 WDR19	3.65e-03	11	247	2	C0265275
Disease	X-11308 measurement	CYP2C19 HEATR4	3.65e-03	11	247	2	EFO_0800693
Disease	non-small cell lung carcinoma	BRCA2 ANKS1A NLRP1 BAZ1A	3.66e-03	75	247	4	EFO_0003060
Disease	Congenital disorder of glycosylation	COG6 DOLK ALG13	3.94e-03	38	247	3	cv:C0282577
Disease	alcohol consumption measurement	PIGN IFT172 SPTBN1 ANKS1B BIRC6 KLHL29 ZBTB37 DNAH5 STK24 ANKS1A VRK1 CIT WDR19 GRIP1 DMC1 IPO9 CERS1 MAPK6 MYO15A MMAB	4.15e-03	1242	247	20	EFO_0007878
Disease	thioredoxin domain-containing protein 12 measurement	DOCK3 TUT4 ARHGEF3	4.24e-03	39	247	3	EFO_0008298
Disease	nervous system disease (implicated_via_orthology)	SKOR1 ATP4A	4.36e-03	12	247	2	DOID:863 (implicated_via_orthology)
Disease	Prenatal Exposure Delayed Effects	BMP2 ATM	4.36e-03	12	247	2	C0033054
Disease	hypertension	MYO1D ERAP1 KLHL29 TTBK1 VPS33B ANK1 RNF213 RANBP3L	4.53e-03	307	247	8	EFO_0000537
Disease	basophil percentage of leukocytes	CDKN2D HIP1 SPTBN1 LYST DSTYK CHORDC1 GRIP1	4.55e-03	243	247	7	EFO_0007992
Disease	Lymphoma	JAK3 BRAF ATM	4.56e-03	40	247	3	C0024299
Disease	amino acid measurement	PIGN GLS2 RYR3 KLHL29 TEKT1 MGAM2 MCOLN2 VRK1 LRRK1 STK32C GRIP2 MAPK6 TNKS2	4.96e-03	678	247	13	EFO_0005134
Disease	Epilepsy, Cryptogenic	RAB39B SLC12A2 CNTNAP2 ALG13	5.03e-03	82	247	4	C0086237
Disease	Awakening Epilepsy	RAB39B SLC12A2 CNTNAP2 ALG13	5.03e-03	82	247	4	C0751111
Disease	Aura	RAB39B SLC12A2 CNTNAP2 ALG13	5.03e-03	82	247	4	C0236018
Disease	Fetal Alcohol Spectrum Disorders	ANK3 GABPA	5.12e-03	13	247	2	C2985290
Disease	acute myeloid leukemia (is_implicated_in)	FANCC KMT2A NUP214 MTRR	5.48e-03	84	247	4	DOID:9119 (is_implicated_in)
Disease	open-angle glaucoma	KMT2A MPP7 LRRC27 EXOC2 ARHGEF3 GABPA	5.58e-03	191	247	6	EFO_0004190
Disease	liver fat measurement	TOR1B RIOX2 CNTNAP2	5.59e-03	43	247	3	EFO_0010821
Disease	Fanconi anemia	FANCC BRCA2	5.94e-03	14	247	2	cv:C0015625
Disease	polycystic kidney disease (implicated_via_orthology)	STAM2 IFT172	5.94e-03	14	247	2	DOID:0080322 (implicated_via_orthology)
Disease	Glioma	BRAF BRCA2 TFRC ATM	6.20e-03	87	247	4	C0017638
Disease	Malignant neoplasm of kidney	ATP7B BRAF BRCA2	6.35e-03	45	247	3	C0740457
Disease	Gastric Adenocarcinoma	TRRAP JAK3 ATM	6.35e-03	45	247	3	C0278701
Disease	abdominal fat cell number	GDAP2 SPTBN1 FLNC DNAJC13 FHOD3 CHORDC1	6.63e-03	198	247	6	EFO_0021534
Disease	Malignant neoplasm of urinary bladder	FANCC BRCA2 KMT2A TFRC ATM	6.79e-03	141	247	5	C0005684
Disease	Benign neoplasm of bladder	FANCC ATM	6.82e-03	15	247	2	C0154017
Disease	Carcinoma in situ of bladder	FANCC ATM	6.82e-03	15	247	2	C0154091
Disease	Meckel-Gruber syndrome	RPGRIP1 RPGRIP1L	6.82e-03	15	247	2	C0265215
Disease	Down syndrome (implicated_via_orthology)	DOP1B DOP1A	6.82e-03	15	247	2	DOID:14250 (implicated_via_orthology)
Disease	Neoplasm of uncertain or unknown behavior of bladder	FANCC ATM	6.82e-03	15	247	2	C0496930
Disease	myopathy (implicated_via_orthology)	NPL FLNC MYBPC2	7.59e-03	48	247	3	DOID:423 (implicated_via_orthology)
Disease	iron biomarker measurement	GHR KLHL29 ANK1	7.59e-03	48	247	3	EFO_0004461
Disease	red blood cell density measurement	GLS2 SPTBN1 ZBTB37 TASOR PREX1 CA8 ANK1 KALRN TFRC SEMA3D BAZ1A AKAP13 ARHGEF3 MYO15A MMAB	7.61e-03	880	247	15	EFO_0007978
Disease	vitamin D measurement, COVID-19	GLS2 SDR42E1 BCAS1	8.04e-03	49	247	3	EFO_0004631, MONDO_0100096

Protein segments in the cluster

Peptide	Gene	Start	Entry
GFDLQETLVKIQAEH	CCT6A	456	P40227
IFVGVEHVNEDAELI	ZNF280B	31	Q86YH2
DHKEIVTNIQRGFIE	ANKRD20A1	756	Q5TYW2
ETEHFNGVAELLEIL	PPP2R5E	231	Q16537
RVVEDFIHLVGDALK	ADGRB2	696	O60241
IEKRIVITGDADIDH	EPB41	816	P11171
NIFLHEDLTVKIGDF	BRAF	581	P15056
VDALHKVGQIVFEFV	NUDT1	61	P36639
VFIEELAEKHVVPLA	ALG13	526	Q9NP73
GVKLHVFLFQEVLVI	ARHGEF3	346	Q9NR81
LFNHQEHKVIIVGLD	ARL5A	11	Q9Y689
DHKEIVTNIQRGFIE	ANKRD20A8P	756	Q5CZ79
LIHVKAVNERGTEEI	BIRC6	1221	Q9NR09
DQGHAKVAQLIVLEV	BPIFB1	351	Q8TDL5
VQEHSLGVLAVLFVK	COPS3	51	Q9UNS2
QVVHKAVLDVFEEGT	SERPINA3	356	P01011
ELDVQIIGVKFHVSS	AZIN1	186	O14977
VKLAEGDHVNSLLEI	AKAP7	181	Q9P0M2
LVSLGHELQVVFKSD	CDCP2	226	Q5VXM1
RDIIKIIEEIGFHAS	ATP7B	616	P35670
DHKEIVTNIQRGFIE	ANKRD20A4P	756	Q4UJ75
ILHLDVGDEVFIKLD	C1QL4	201	Q86Z23
ENHLEVVKFLLENGA	ANK1	121	P16157
KVILIQASDVGDVHE	GSDMA	241	Q96QA5
LIVREVAHEEKGLFL	AKAP13	2286	Q12802
EVHKASLIIDLFGNE	C14orf28	121	Q4W4Y0
GVTLAQDHFQEIEKI	ABCA13	2976	Q86UQ4
DLQDVTHKIVDAIGA	DOP1A	1966	Q5JWR5
LHEAALFGKTDVVQI	ANKS1A	251	Q92625
EQGLFDVHSVLRVVL	CD276	416	Q5ZPR3
DELTFKEGEIIHLIS	CD2AP	286	Q9Y5K6
SAIEESIGLHLVEKE	ANKRD12	791	Q6UB98
FLDTLKVLVEHGADV	CDKN2D	86	P55273
HEEAGIFKLLIIDSI	DMC1	211	Q14565
FEIVQGLLEIQHLTE	DGCR6	61	Q14129
VSKEADGLVLINIDH	DENND3	276	A2RUS2
FVVEVAHLEEKQGVS	BMP2	226	P12643
FRHLVGDSLIKVDVV	BCO2	486	Q9BYV7
IDEILKINEDTRVHG	MTHFD1L	141	Q6UB35
QLQSKLHEADIVVLG	MTHFD1L	256	Q6UB35
NILVDRTGHIKLVDF	CIT	226	O14578
EENILIIHGTADTKV	DPP10	716	Q8N608
GVHELSAFEQLVVEL	BAZ1A	1431	Q9NRL2
LKEQVSDICIIGEHI	NBEAL1	2586	Q6ZS30
KLVTLVHCQLVEEEG	RC3H1	136	Q5TC82
IVFVLVGHKCDLDTQ	RAB39B	116	Q96DA2
QDFHEVEDLIKTAIG	PBLD	131	P30039
LFHTIGVEFLNKDLE	RAB9A	36	P51151
TAKGHIVLLQEAETL	INTS9	611	Q9NV88
HEVVDGEARKTEVLL	JAK3	541	P52333
GQVLLDVVFKHLDLT	PTPN4	51	P29074
GLSAHSKVLVEVVDV	PCDHB1	326	Q9Y5F3
FEVTILGLNHEIAID	RADX	751	Q6NSI4
DHKEIVTNIQRGFIE	ANKRD20A2P	756	Q5SQ80
KLLHDSGLNVVVLEA	MAOB	21	P27338
HEAALFGKVDVVRVL	ANKS1B	231	Q7Z6G8
EFKQGLAITHEILLS	PAPOLB	341	Q9NRJ5
RFLEIHGETIEKVVF	GDAP2	191	Q9NXN4
HGETIEKVVFAVSDL	GDAP2	196	Q9NXN4
LNVKAGDIITVLEQH	CASKIN1	301	Q8WXD9
IFVLLHIDNSGIREK	NUP98	1566	P52948
AEHIFGATEIILLTV	OR4C12	101	Q96R67
GIDSLIEHLEVAIKN	KCTD9	176	Q7L273
VSVEGEQHEKAVELL	LIN7B	146	Q9HAP6
KHSLSVGEVIEVLEV	DOLK	156	Q9UPQ8
ERGENLFEIHINKVT	RPGRIP1L	601	Q68CZ1
QLLFVHQGETELKEL	GRWD1	406	Q9BQ67
VIVDGSLDHETQVKL	MGAM2	1316	Q2M2H8
VVLVVGTHLDLIEAK	LRRK1	751	Q38SD2
AHQVKTLVDDFILEL	MYO15A	2851	Q9UKN7
KGDFLLVSEHVIELL	MYO1A	966	Q9UBC5
HAFQLIQKELIEEFG	EDRF1	1116	Q3B7T1
HLVEEAQVITLDGTK	GABPA	136	Q06546
GSIIAVEKIVHIAND	PHKA1	1146	P46020
IGNIEKPVEIFHIIE	METTL14	321	Q9HCE5
LVEGLAEILHQKFID	DOP1B	336	Q9Y3R5
QELEIVIGDEHISFT	MAGOH	86	P61326
HDALVQIISKEVGVE	MTRR	661	Q9UBK8
HQEVVELLIKYGADV	GABPB1	116	Q06547
DLLVGVIHVLSKEIE	FSIP2	3606	Q5CZC0
EGKSHFQILLDVVQF	HSPB3	66	Q12988
SLHGFILVTALVEKE	IDO2	176	Q6ZQW0
LVKSVTVAEGLIEDH	ERAP1	221	Q9NZ08
GLLERVNTEIHFVTK	FLT3LG	96	P49771
IIAVHAEVFTISKEL	EXOC2	806	Q96KP1
LKEHLGEQEVSISLI	IL1RAPL1	306	Q9NZN1
RLDHDNIVKVFEILG	MAPK6	71	Q16659
SLLEGEAVEVIHKLL	NCF1	246	P14598
VEVVLDKLHGQVLSQ	NLRP1	1396	Q9C000
LGKFAEVEHVVNAIL	DCXR	206	Q7Z4W1
VHEKFTLIDGIRVAT	FAM83D	241	Q9H4H8
EILSDAGVKAEVLIH	FLNC	1191	Q14315
DEATLKQLDGIHVTI	IL16	1101	Q14005
GADLENKVITVHRVF	IL16	1131	Q14005
KLIDLEDAVQISGHF	KALRN	2821	O60229
GHLFDKIIINDDLTV	MPP7	536	Q5T2T1
KVHAEEVIVLLLEGS	KDM3B	81	Q7LBC6
IGEEIAHFQKELEEL	NUP214	706	P35658
GEEKHLEVQILLENT	LCA5L	431	O95447
AAAEGHIEVVKFLIE	GLS2	526	Q9UI32
LTGHEEKVSVENFEL	RPS6KA4	21	O75676
LKHLEGISDEDIINI	BPGM	196	P07738
VQKFTEDLVGSVVHV	MEAK7	126	Q6P9B6
LDLGHFSKVDFIIIV	GREB1L	696	Q9C091
QIALDVVEGIRFLHS	DSTYK	756	Q6XUX3
DDVIVFLHIQKTGGT	HS6ST1	86	O60243
VSLLEGEAVEVIHKL	NCF1B	246	A6NI72
VSLLEGEAVEVIHKL	NCF1C	221	A8MVU1
TELVEHITAALIKGE	IFT172	796	Q9UG01
LEEGATLIAHKVDEQ	KIF19	26	Q2TAC6
EDIKLVEHGLNETIH	NUP54	486	Q7Z3B4
HDQVTLLKAGTFEVL	NR1D1	466	P20393
LEALLKHVTTQGVEE	COG6	326	Q9Y2V7
GDIVLLLQEKEHEVF	DNAJA2	246	O60884
DFLTIVRECGIEKHQ	ATM	661	Q13315
VHIDLGVAFEQGKIL	ATM	2886	Q13315
DHKEIVTNIQRGFIE	ANKRD20A3P	756	Q5VUR7
EIVEHFLSLGLEINA	ANKRD2	261	Q9GZV1
TLILEGEHNIEVKEQ	ARMC8	561	Q8IUR7
IEHVIVDGVVQSIKL	IDH3A	156	P50213
DHKVLVLDSGNLIAV	IL37	66	Q9NZH6
EEVVLLTHGDSVDKV	GMPS	146	P49915
VLHGYEVVKEALIDL	CYP2C19	76	P33261
VHSLGVNDILEIKFF	CPSF6	101	Q16630
SLEVAAKILIGEDHV	E2F8	286	A0AVK6
HVSGEEIVKFLQDIL	DOCK3	631	Q8IZD9
AQILEFGLAVHEKFV	DOCK4	1551	Q8N1I0
LKEATVEDLGQHETV	DOCK5	66	Q9H7D0
GLEVITRVHKDVELA	DOCK6	976	Q96HP0
IKFIQGDIRHLSDVE	SDR42E1	51	Q8WUS8
VKGVLEEFDLIRTEH	BRCA2	2076	P51587
VSLVENIHVLGKEQA	BRCA2	2171	P51587
EGKLEEVNTILAIHD	GHR	316	P10912
LKEVVVGNHLESIFL	CDK10	101	Q15131
HVGLKAVTEILQDIQ	CA8	176	P35219
VHEFVVAEGLTCLIK	FHOD3	141	Q2V2M9
FDEVQIIHQIGAKRD	HEATR4	356	Q86WZ0
AEITHEIIGFLDQTL	FANCC	516	Q00597
ESVLEVHGKFVQLIN	CUL2	341	Q13617
KAHQEEIAGAFLVTL	C1orf112	296	Q9NSG2
HLETVDGAKVVVLVN	DHX58	41	Q96C10
ESEGIHEVLVFAIQK	ACTR1A	271	P61163
DAVLVAVKGAHVEQL	CCDC57	296	Q2TAC2
ASKEGHVEVVSELLQ	ANK3	81	Q12955
VGILVLFLHDISDVQ	CERS1	201	P27544
FEIVQGLLEIQHLTE	DGCR6L	61	Q9BY27
LFDTQLIIEKAEHGD	TMBIM6	186	P55061
DHAKELIVGEIFVRV	DNAJC13	1681	O75165
LDVLAHVFESFLKII	LYST	1286	Q99698
AEVGDVIVIHLKNFA	HEPHL1	106	Q6MZM0
QIKVLEVTEEFGVHL	IPO9	46	Q96P70
GILHDAVVFLIEQLS	KMT2A	3721	Q03164
FDIKGDDLIVFLHIQ	HS6ST2	221	Q96MM7
VLELVAQVLEHKAIG	CASQ2	76	O14958
NVEIDLTESKVGVHI	CNTNAP2	421	Q9UHC6
FQLGESEEHIELVVL	EMB	241	Q6PCB8
HVNIVKFNVEDGEIV	EMC1	196	Q8N766
SVIIFVDKQEHADGL	DDX46	621	Q7L014
KLETFIQEHLRVIGA	CD151	211	P48509
AAVDLEVLGVAIQKH	GPRIN2	396	O60269
VIFRTVEVTLHKEGN	GRIP1	146	Q9Y3R0
AALAHKVVLEVEFDV	GRIP2	531	Q9C0E4
TVQHLEEVDLGISVK	BCAS1	41	O75363
LVESIHVNLEKALGI	SACS	1201	Q9NZJ4
AIEIEHFVDIIAGLA	ATP4A	296	P20648
HLDEEVNKGDILVVA	MTHFD1	201	P11586
HLDEVFLELKDGQQI	COA1	116	Q9GZY4
IATVEKQLLGEHLTA	CUL4B	441	Q13620
SFGEEVEVHNLLIID	DDB1	781	Q16531
VEISFHLKGIDLQTI	MCOLN2	221	Q8IZK6
EEIHVGLEASLLVKA	DNAH5	686	Q8TE73
ELVTEKGHTFAEELQ	MMAB	101	Q96EY8
VEALNAVHGFIAEKI	NOVA1	106	P51513
LLTAVQEHGAKLEIV	MROH5	761	Q6ZUA9
GQVKTVLNVLHDFEE	MROH2A	736	A6NES4
IHTIEELDFIISQLG	MRC1	401	P22897
ELTGKVEAEFHLVTA	FER1L6	1761	Q2WGJ9
DKLDQVIIHVGALSL	NPL	76	Q9BXD5
VIIHVGALSLKESQE	NPL	81	Q9BXD5
DNKIHGEILVTSAID	TARS3	771	A2RTX5
TDIKIATGHNIIDEL	SYPL1	176	Q16563
YEKHAEILQEVLGEV	AK9	601	Q5TCS8
DVTGTHLVEKDIENL	SKOR1	846	P84550
IVKLHRIGDFIDVSE	MRPL39	251	Q9NYK5
KLTEFEEAIGVIFTH	DROSHA	1106	Q9NRR4
VIGIDHIKELVDDSV	PCMT1	106	P22061
HGLDDIQTLIKTLIF	TRMT1L	551	Q7Z2T5
GALLAVEHVKDDVSI	EPRS1	16	P07814
FDRVLETVEKVHGLA	RPGRIP1	721	Q96KN7
ETVLAIDAIHQLGFI	STK38L	196	Q9Y2H1
DETGVALKVIHELAN	TOP2B	301	Q02880
IKLINIHVTDIIDGN	SYNE2	106	Q8WXH0
EDLIIKGISVHISNA	TARDBP	246	Q13148
RQEIVEHVKADVLGD	LRRC27	266	Q9C0I9
DIKAANVLLSEHGEV	STK24	156	Q9Y6E0
EVGDVILIHLKNFAT	HEPH	106	Q9BQS7
VVLQLKGHVSELEAD	HIP1	401	O00291
NTGILHDEILIHEEK	POTEJ	571	P0CG39
VKVLFSNIEDILEVH	PREX1	96	Q8TCU6
TVEHELIKEAEIIQG	TEKT1	131	Q969V4
IGIDLVHDNVEKNLI	TEKT5	201	Q96M29
FEIGQILHDNVILKS	NAP1L3	466	Q99457
VVHFLLVKRDESGAI	VPS8	376	Q8N3P4
GKVQLHLIESEILDA	WDR19	446	Q8NEZ3
IKFVQHDAVEGILIV	SHCBP1	436	Q8NEM2
GTDHFVIIAQLKEEV	FAM76A	211	Q8TAV0
EEGLFVVHVTKDEII	CDC42BPA	1246	Q5VT25
AEVAGQFVIKLTHDV	TFRC	591	P02786
EVVLEELQIFKHSSI	SEMA3D	491	O95025
LGVEDLLQKHTLVEA	SPTBN1	561	Q01082
HLTDFNIATIIKDGE	STK32C	231	Q86UX6
EFVDGLHEKLNTIII	TASOR	1076	Q9UK61
LIIIQNEDIAGFIHK	TASOR	1276	Q9UK61
GEIIIADNIIKFDHV	ABCD3	431	P28288
DIVVRKEEGFTHILL	CDYL2	251	Q8N8U2
EVTLEKEGQVLLHFA	CIAO3	351	Q9H6Q4
STLLNVHIVFEGEKE	CHORDC1	261	Q9UHD1
VVEDKHGLESQIEAL	C10orf67	401	Q8IYJ2
LEIITQLIVESFHFK	SLC34A2	241	O95436
NVKHLIQVDFGVLAV	RNF213	1166	Q63HN8
LEHQGIKIEFIGQIE	VPS26B	61	Q4G0F5
GKQHVVSVEEALLAT	THBS1	136	P07996
KQILESIEAIHSVGF	TTBK1	136	Q5TCY1
ILEGIHFKINVAEVE	ZBTB37	121	Q5TC79
TVERFGKEHAVIILN	AGPAT3	81	Q9NRZ7
LLLQEHFGEIVEKIG	POLR3C	11	Q9BUI4
GFIIEAEHKTVLTEE	NME8	181	Q8N427
IQFLDTAGIHTLKEV	SLC26A2	656	P50443
EITIVHDADLQIGKL	ILDR2	121	Q71H61
EALNLIAEGHIKSII	RYR3	571	Q15413
KIDVITGEETEHNVL	RANBP3L	286	Q86VV4
GFAETVVELLKEHSI	SLC12A2	386	P55011
EQFVHKVVRDILLIG	PITPNC1	201	Q9UKF7
HFVKIDQETLLIIDS	PIGH	81	Q14442
TAAEVGIIESIHLKN	SMC6	41	Q96SB8
HITEGIQEDSLKVLD	TEX10	151	Q9NXF1
VEDNELTFKHGEIII	STAM2	216	O75886
LTFKHGEIIIVLDDS	STAM2	221	O75886
GEFGSEILVQKVVHT	VCPIP1	636	Q96JH7
EEKIVFFLHLLGIDT	PIGN	201	O95427
DDVEVFILQLEGEKH	RIOX2	181	Q8IUF8
LIESLIEGHFFKEAI	SLF1	416	Q9BQI6
ELLVKHGAVVNVADL	TNKS2	576	Q9H2K2
KRHLAEQFAVGEIIT	VRK1	16	Q99986
GLVIKQEASEETELH	ZNF621	96	Q6ZSS3
EHLLRQESKEGAFIV	TXK	161	P42681
NEVTAHELGKEAVLL	ZNF75D	136	P51815
IVKIEEEEFIHGQDT	ZNF165	21	P49910
QSGEEAVALVVHLEK	ZKSCAN2	111	Q63HK3
IASEIAVDIVKHAFI	TAPT1	346	Q6NXT6
GIEIVELQLSHVKDL	ZNF131	246	P52739
FRLIKEGETITEVIH	POSTN	711	Q15063
SVAVIELAKEHGITD	TUT4	356	Q5TAX3
TGILQDEILIHEEKQ	POTEG	486	Q6S5H5
TGILQDEILIHEEKQ	POTEM	486	A6NI47
KFLEGATIEVDQIHT	TRRAP	1411	Q9Y4A5
QELIKTEHALLEGFN	VPS33B	361	Q9H267
HLDSVGEITKEDLIQ	USP33	41	Q8TEY7
TVLIDDIEVQGHKIV	ZBTB26	36	Q9HCK0
DLEEKLFGQHLATEV	TOR1B	71	O14657
ERHLEVKVNVTGTEF	VPS13D	2461	Q5THJ4
LKIVVEGREFEVHQN	KLHL29	331	Q96CT2
LLEHLFDVDVKTGAQ	NLRP14	161	Q86W24
IVDLVEQQHKGIIAI	MYO1D	441	O94832
LAAILHLGNIEFVET	MYO1G	276	B0I1T2
LLQHKFITQIEGKDV	MYO3A	281	Q8NEV4
DLKHIVIDGSNVAIT	N4BP1	616	O75113
VEGHVFLLDVLALSQ	EXD3	421	Q8N9H8
LQAVHLEGEKEIAIY	MYOM2	486	P54296
GKRHILIFSDVVQED	MYBPC2	401	Q14324
GVVAQAVHELLEKEN	GRIN1	286	Q05586