Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesshippo signaling

TEAD2 TEAD1 TEAD4 TEAD3

3.85e-0655404GO:0035329
GeneOntologyCellularComponentTEAD-YAP complex

TEAD2 TEAD1

1.07e-053402GO:0140552
DomainTEA

TEAD2 TEAD1 TEAD4 TEAD3

1.80e-114404PF01285
DomainTEA_1

TEAD2 TEAD1 TEAD4 TEAD3

1.80e-114404PS00554
DomainTEA/ATTS_dom

TEAD2 TEAD1 TEAD4 TEAD3

1.80e-114404IPR000818
DomainTEF_metazoa

TEAD2 TEAD1 TEAD4 TEAD3

1.80e-114404IPR016361
DomainTEA

TEAD2 TEAD1 TEAD4 TEAD3

1.80e-114404SM00426
DomainTEA_2

TEAD2 TEAD1 TEAD4 TEAD3

1.80e-114404PS51088
DomainHomeodomain-like

GON4L TEAD1 TEAD4 TEAD3 TSHZ2

6.80e-04332405IPR009057
DomainABC_membrane

ABCB5 CFTR

1.20e-0324402PF00664
DomainABC_TM1F

ABCB5 CFTR

1.63e-0328402PS50929
DomainABC1_TM_dom

ABCB5 CFTR

1.63e-0328402IPR011527
DomainPDZ

SHROOM4 RIMS1 SIPA1L1

3.39e-03141403PF00595
DomainABC_transporter_CS

ABCB5 CFTR

3.65e-0342402IPR017871
DomainPDZ

SHROOM4 RIMS1 SIPA1L1

3.89e-03148403SM00228
Domain-

SHROOM4 RIMS1 SIPA1L1

4.04e-031504032.30.42.10
DomainPDZ

SHROOM4 RIMS1 SIPA1L1

4.11e-03151403PS50106
DomainPDZ

SHROOM4 RIMS1 SIPA1L1

4.19e-03152403IPR001478
DomainABC_TRANSPORTER_2

ABCB5 CFTR

4.74e-0348402PS50893
DomainABC_tran

ABCB5 CFTR

4.74e-0348402PF00005
DomainABC_TRANSPORTER_1

ABCB5 CFTR

4.94e-0349402PS00211
DomainABC_transporter-like

ABCB5 CFTR

5.13e-0350402IPR003439
DomainEGF_CA

LRP1 FAT3

1.46e-0286402PF07645
PathwayREACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION

HIPK2 TEAD2 TEAD1 TEAD4 TEAD3

1.08e-1015315M603
PathwayREACTOME_RUNX3_REGULATES_YAP1_MEDIATED_TRANSCRIPTION

TEAD2 TEAD1 TEAD4 TEAD3

2.86e-106314MM15544
PathwayREACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION

TEAD2 TEAD1 TEAD4 TEAD3

1.33e-098314MM14816
PathwayREACTOME_RUNX3_REGULATES_YAP1_MEDIATED_TRANSCRIPTION

TEAD2 TEAD1 TEAD4 TEAD3

1.33e-098314M27823
PathwayWP_MIR5093P_ALTERATION_OF_YAP1ECM_AXIS

TEAD2 TEAD1 TEAD4 TEAD3

5.73e-0818314M39421
PathwayWP_TRANSCRIPTION_COFACTORS_SKI_AND_SKIL_PROTEIN_PARTNERS

TEAD2 TEAD1 TEAD4 TEAD3

5.73e-0818314M39825
PathwayWP_HIPPOYAP_SIGNALING

TEAD2 TEAD1 TEAD4 TEAD3

1.36e-0722314M39821
PathwayWP_LEUKOCYTEINTRINSIC_HIPPO_PATHWAY_FUNCTIONS

TEAD2 TEAD1 TEAD4 TEAD3

9.55e-0735314M39430
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

TEAD2 TEAD1 TEAD4 TEAD3

3.19e-0647314M39829
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

TEAD2 TEAD1 TEAD4 TEAD3

2.20e-0576314MM15520
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

TEAD2 TEAD1 TEAD4 TEAD3

5.52e-0596314M27784
PathwayWP_HIPPO_SIGNALING_REGULATION

TEAD2 TEAD1 TEAD4 TEAD3

5.98e-0598314M39830
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

TEAD2 TEAD1 TEAD4 TEAD3

1.36e-04121314M39823
PathwayREACTOME_FORMATION_OF_AXIAL_MESODERM

TEAD2 TEAD4

4.19e-0414312M46441
Pubmed

A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain.

TEAD2 TEAD1 TEAD4 TEAD3

1.84e-1244248702974
Pubmed

Comparative expression analysis of TEADs and their splice variants in mouse embryonic stem cells.

TEAD2 TEAD1 TEAD4 TEAD3

1.84e-12442436516960
Pubmed

Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis.

TEAD2 TEAD1 TEAD4 TEAD3

1.84e-1244249889009
Pubmed

The TEA domain: a novel, highly conserved DNA-binding motif.

TEAD2 TEAD1 TEAD4 TEAD3

1.84e-1244242070413
Pubmed

Transcription factor mTEAD-2 is selectively expressed at the beginning of zygotic gene expression in the mouse.

TEAD2 TEAD1 TEAD4 TEAD3

1.84e-1244249169843
Pubmed

Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth.

MKI67 TEAD2 TEAD1 TEAD4 TEAD3

2.56e-121342533984529
Pubmed

Differential expression of the TEF family of transcription factors in the murine placenta and during differentiation of primary human trophoblasts in vitro.

TEAD2 TEAD1 TEAD4 TEAD3

9.17e-1254249671946
Pubmed

Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments.

TEAD2 TEAD1 TEAD4 TEAD3

9.17e-12542421527258
Pubmed

TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.

TEAD2 TEAD1 TEAD4 TEAD3

9.17e-12542419324877
Pubmed

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP.

TEAD2 TEAD1 TEAD4 TEAD3

9.17e-12542422677547
Pubmed

TEAD mediates YAP-dependent gene induction and growth control.

TEAD2 TEAD1 TEAD4 TEAD3

9.17e-12542418579750
Pubmed

TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation.

TEAD2 TEAD1 TEAD4 TEAD3

9.17e-12542410518497
Pubmed

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors.

FGF8 TEAD2 TEAD1 TEAD4 TEAD3

2.30e-111942520596238
Pubmed

TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm.

TEAD2 TEAD1 TEAD4 TEAD3

2.75e-11642411358867
Pubmed

Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63 Transcription through TEA Domain (TEAD) Transcription Factor.

TEAD2 TEAD1 TEAD4 TEAD3

2.75e-11642425995450
Pubmed

Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of Tead2 as a regulator of Pax3.

TEAD2 TEAD1 TEAD4 TEAD3

6.41e-11742414736747
Pubmed

Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor.

TEAD2 TEAD1 TEAD4 TEAD3

6.41e-11742416207754
Pubmed

A novel family of TEA domain-containing transcription factors with distinct spatiotemporal expression patterns.

TEAD1 TEAD4 TEAD3

1.64e-0934238920920
Pubmed

VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle.

TEAD1 TEAD4 TEAD3

6.54e-09442331138678
Pubmed

YAP/TEAD-mediated transcription controls cellular senescence.

TEAD1 TEAD4 TEAD3

6.54e-09442323576552
Pubmed

Tead transcription factors differentially regulate cortical development.

TEAD2 TEAD1 TEAD3

6.54e-09442332170161
Pubmed

cDNA cloning and characterization of mouse DTEF-1 and ETF, members of the TEA/ATTS family of transcription factors.

TEAD2 TEAD4 TEAD3

6.54e-0944239502435
Pubmed

Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype.

TEAD2 TEAD1 TEAD4 TEAD3

8.77e-092042418978355
Pubmed

Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos.

TEAD2 TEAD1 TEAD4 TEAD3

1.60e-082342418083014
Pubmed

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation.

TEAD1 TEAD4 TEAD3

1.63e-08542320516196
Pubmed

Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions.

TEAD1 TEAD4 TEAD3

5.71e-08742312861002
Pubmed

Mechanosignalling via integrins directs fate decisions of pancreatic progenitors.

TEAD2 TEAD1 TEAD4 TEAD3

6.44e-083242430487608
Pubmed

AMPK modulates Hippo pathway activity to regulate energy homeostasis.

TEAD2 TEAD1 TEAD4

1.95e-071042325751139
Pubmed

Cloning of human RTEF-1, a transcriptional enhancer factor-1-related gene preferentially expressed in skeletal muscle: evidence for an ancient multigene family.

TEAD1 TEAD4

1.42e-0624228921372
Pubmed

Cellular prion protein participates in amyloid-β transcytosis across the blood-brain barrier.

LRP1 PRNP

1.42e-06242222293988
Pubmed

TEAD1 and TEAD3 Play Redundant Roles in the Regulation of Human Epidermal Proliferation.

TEAD1 TEAD3

1.42e-06242232142794
Pubmed

Myofiber-specific TEAD1 overexpression drives satellite cell hyperplasia and counters pathological effects of dystrophin deficiency.

TEAD1 DMD

1.42e-06242227725085
Pubmed

Neuronal low-density lipoprotein receptor-related protein 1 binds and endocytoses prion fibrils via receptor cluster 4.

LRP1 PRNP

1.42e-06242220048341
Pubmed

TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo.

TEAD1 TEAD4

1.42e-06242228178271
Pubmed

A Soluble PrPC Derivative and Membrane-Anchored PrPC in Extracellular Vesicles Attenuate Innate Immunity by Engaging the NMDA-R/LRP1 Receptor Complex.

LRP1 PRNP

4.27e-06342234810220
Pubmed

The LRP1/CD91 ligands, tissue-type plasminogen activator, α2-macroglobulin, and soluble cellular prion protein have distinct co-receptor requirements for activation of cell-signaling.

LRP1 PRNP

4.27e-06342236266319
Pubmed

Three-dimensional mapping reveals heterochronic development of the neuromuscular system in postnatal mouse skeletal muscles.

MKI67 DMD

4.27e-06342236347940
Pubmed

Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor.

TEAD1 TEAD4

4.27e-06342228077648
Pubmed

Genetic variants in Hippo pathway genes YAP1, TEAD1 and TEAD4 are associated with melanoma-specific survival.

TEAD1 TEAD4

4.27e-06342225628125
Pubmed

Smooth muscle cells and myofibroblasts use distinct transcriptional mechanisms for smooth muscle alpha-actin expression.

TEAD1 TEAD4

4.27e-06342217823374
Pubmed

TEAD1/4 exerts oncogenic role and is negatively regulated by miR-4269 in gastric tumorigenesis.

TEAD1 TEAD4

4.27e-06342228759040
Pubmed

9p21.3 Coronary Artery Disease Risk Variants Disrupt TEAD Transcription Factor-Dependent Transforming Growth Factor β Regulation of p16 Expression in Human Aortic Smooth Muscle Cells.

TEAD4 TEAD3

4.27e-06342226487755
Pubmed

Functional interaction between the p160 coactivator proteins and the transcriptional enhancer factor family of transcription factors.

TEAD2 TEAD1

4.27e-06342210934189
Pubmed

Cell competition in mouse NIH3T3 embryonic fibroblasts is controlled by the activity of Tead family proteins and Myc.

TEAD2 TEAD1

4.27e-06342225588835
Pubmed

Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells.

MKI67 LRP1 FGF8

7.19e-063142319796621
Pubmed

Paraxis: a basic helix-loop-helix protein expressed in paraxial mesoderm and developing somites.

TEAD4 TEAD3

8.53e-0644227729571
Pubmed

Loss of β2-spectrin prevents cardiomyocyte differentiation and heart development.

MKI67 DMD

8.53e-06442224064296
Pubmed

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway.

TEAD1 TEAD4

8.53e-06442225751140
Pubmed

Transcription factor TEAD2 is involved in neural tube closure.

TEAD2 TEAD4

8.53e-06442217868131
Pubmed

A census of human transcription factors: function, expression and evolution.

GON4L TEAD2 TEAD1 TEAD4 TEAD3 ZNF274 TSHZ2 MAZ

1.12e-0590842819274049
Pubmed

Global gene expression analysis of murine limb development.

FGF8 TEAD2 ZNF274 TSHZ2

1.23e-0511742422174793
Pubmed

Piezo1 regulates the regenerative capacity of skeletal muscles via orchestration of stem cell morphological states.

MKI67 DMD

1.42e-05542235302846
Pubmed

Genomic structure and chromosomal mapping of the mouse transcription factor TEF-5 (Tead3) gene.

TEAD2 TEAD3

1.42e-05542210341100
Pubmed

Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1.

LRP1 PRNP

1.42e-05542223386614
Pubmed

Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ.

MKI67 DNMT3A

1.42e-05542228425913
Pubmed

Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif.

TEAD1 TEAD4 TEAD3

1.57e-054042330865227
Pubmed

Lhx9 gene expression during early limb development in mice requires the FGF signalling pathway.

MKI67 FGF8

2.13e-05642226220830
Pubmed

Ascl2 inhibits myogenesis by antagonizing the transcriptional activity of myogenic regulatory factors.

MKI67 DMD

2.98e-05742227993983
Pubmed

The cellular prion protein colocalizes with the dystroglycan complex in the brain.

DMD PRNP

2.98e-05742211032878
Pubmed

Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions.

FGF8 DNMT3A

2.98e-05742231558711
Pubmed

Limb deformity proteins: role in mesodermal induction of the apical ectodermal ridge.

FGF8 FMN1

2.98e-0574229006074
Pubmed

The limb deformity mutation disrupts the SHH/FGF-4 feedback loop and regulation of 5' HoxD genes during limb pattern formation.

FGF8 FMN1

2.98e-0574228575323
Pubmed

Meso1, a basic-helix-loop-helix protein involved in mammalian presomitic mesoderm development.

TEAD4 TEAD3

3.97e-0584227597044
Pubmed

Caudal regression in adrenocortical dysplasia (acd) mice is caused by telomere dysfunction with subsequent p53-dependent apoptosis.

MKI67 FGF8

3.97e-05842219660449
Pubmed

Influence of mesodermal Fgf8 on the differentiation of neural crest-derived postganglionic neurons.

MKI67 FGF8

3.97e-05842222040872
Pubmed

Molecular architecture of lineage allocation and tissue organization in early mouse embryo.

TEAD1 TEAD4

3.97e-05842231391582
Pubmed

Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-TEAD2 signaling pathway downstream of LIF.

TEAD2 TEAD1

3.97e-05842221385842
Pubmed

Temporal and spatial expression profiles of the Fat3 protein, a giant cadherin molecule, during mouse development.

FAT3 PRNP

3.97e-05842217131403
Pubmed

Development of the mammalian urethra is controlled by Fgfr2-IIIb.

MKI67 FGF8

3.97e-05842215843416
Pubmed

Atlas of Musculoskeletal Stem Cells with the Soft and Hard Tissue Differentiation Architecture.

MKI67 DMD

3.97e-05842233304744
Pubmed

TET1 regulates fibroblast growth factor 8 transcription in gonadotropin releasing hormone neurons.

FGF8 DNMT3A

5.10e-05942231361780
Pubmed

Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development.

TEAD2 TEAD4

5.10e-05942217913785
Pubmed

Formin1 disruption confers oligodactylism and alters Bmp signaling.

FGF8 FMN1

5.10e-05942219383632
Pubmed

Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud.

FGF8 FMN1

5.10e-0594227588050
Pubmed

Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning.

FGF8 FMN1

6.37e-051042212808456
Pubmed

Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation.

MKI67 FGF8

6.37e-051042216192310
Pubmed

Region-specific gene expression profiling of early mouse mandible uncovered SATB2 as a key molecule for teeth patterning.

MKI67 RERG

6.37e-051042239107332
Pubmed

Interplay between Pitx2 and Pax7 temporally governs specification of extraocular muscle stem cells.

MKI67 DMD

6.37e-051042238875306
Pubmed

Early embryogenesis in CHDFIDD mouse model reveals facial clefts and altered cranial neurogenesis.

MKI67 FGF8

6.37e-051042238511331
Pubmed

Fgf receptor 3 activation promotes selective growth and expansion of occipitotemporal cortex.

MKI67 FGF8

6.37e-051042219192266
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

MKI67 LRP1 NPHP4 SIPA1L1

7.25e-0518442432908313
Pubmed

Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood.

MKI67 FGF8

7.78e-051142219429790
Pubmed

Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients.

FMN1 CFTR

7.78e-051142219096130
Pubmed

Disruption of G-protein γ5 subtype causes embryonic lethality in mice.

MKI67 FGF8

7.78e-051142224599258
Pubmed

Ectodermal Organ Development Is Regulated by a microRNA-26b-Lef-1-Wnt Signaling Axis.

MKI67 FGF8

7.78e-051142232760291
Pubmed

Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers.

MKI67 DMD

7.78e-051142221989910
Pubmed

PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors.

MKI67 DMD

7.78e-051142237883229
Pubmed

Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina.

MKI67 DNMT3A

9.32e-051242221452232
Pubmed

Insm1 promotes neurogenic proliferation in delaminated otic progenitors.

MKI67 FGF8

9.32e-051242226545349
Pubmed

Pancreatic neurogenin 3-expressing cells are unipotent islet precursors.

MKI67 FGF8

9.32e-051242219793886
Pubmed

Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development.

MKI67 FGF8

9.32e-051242223444360
Pubmed

Hes1 expression is reduced in Tbx1 null cells and is required for the development of structures affected in 22q11 deletion syndrome.

MKI67 FGF8

1.10e-041342220122914
Pubmed

Sonic hedgehog is essential for first pharyngeal arch development.

MKI67 FGF8

1.10e-041342216492970
Pubmed

SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline.

MKI67 DNMT3A

1.10e-041342234912016
Pubmed

Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy.

FGF8 DMD

1.10e-041342226237517
Pubmed

Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice.

LRP1 FGF8

1.10e-041342216207730
Pubmed

RING1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis2 expression.

MKI67 FGF8

1.28e-041442226674308
Pubmed

Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity.

FGF8 FMN1

1.28e-04144229834182
Pubmed

Sufu and Kif7 in limb patterning and development.

MKI67 FGF8

1.28e-041442225581370
Pubmed

VGLL4 plays a critical role in heart valve development and homeostasis.

MKI67 CCNB2

1.28e-041442230789911
InteractionVGLL3 interactions

ZNF34 TEAD2 TEAD1 TEAD4 TEAD3 CFTR

5.00e-0972396int:VGLL3
InteractionVGLL1 interactions

TEAD2 TEAD1 TEAD4 TEAD3

2.80e-0817394int:VGLL1
InteractionTIAM1 interactions

ZNF34 DMD INPP5E SIPA1L1 MAZ CFTR SRSF12

1.19e-07205397int:TIAM1
InteractionVGLL4 interactions

TEAD2 TEAD1 TEAD4 TEAD3

1.74e-0726394int:VGLL4
InteractionMYH7 interactions

CLINT1 TEAD1 TEAD4 TEAD3 CFTR

1.44e-06101395int:MYH7
InteractionLIMA1 interactions

MKI67 CLINT1 NPHP4 INPP5E SIPA1L1 CFTR SRSF12

1.61e-05429397int:LIMA1
InteractionGIGYF1 interactions

TSHZ2 INPP5E SIPA1L1 PRNP SRSF12

2.23e-05177395int:GIGYF1
InteractionST6GALNAC1 interactions

ST6GALNAC1 CFTR

3.64e-055392int:ST6GALNAC1
InteractionVGLL2 interactions

TEAD1 TEAD3

3.64e-055392int:VGLL2
InteractionEXOC3L4 interactions

NPHP4 PRNP

5.45e-056392int:EXOC3L4
InteractionCLBA1 interactions

FAT3 PRNP

5.45e-056392int:CLBA1
InteractionMAP3K21 interactions

CLINT1 INPP5E SIPA1L1 SRSF12

6.40e-05112394int:MAP3K21
InteractionMELK interactions

MKI67 LRP1 SIPA1L1 SRSF12

6.40e-05112394int:MELK
InteractionDCLK1 interactions

INPP5E SIPA1L1 CFTR SRSF12

1.04e-04127394int:DCLK1
InteractionKSR1 interactions

INPP5E SIPA1L1 PRNP SRSF12

1.21e-04132394int:KSR1
InteractionBCAS1 interactions

PRNP CFTR

1.63e-0410392int:BCAS1
InteractionMMP17 interactions

LRP1 PRNP

1.63e-0410392int:MMP17
InteractionPHLDB2 interactions

INPP5E SIPA1L1 CFTR SRSF12

1.65e-04143394int:PHLDB2
InteractionMAGI1 interactions

INPP5E SIPA1L1 PRNP SRSF12

1.83e-04147394int:MAGI1
InteractionCGN interactions

INPP5E SIPA1L1 CFTR SRSF12

2.08e-04152394int:CGN
InteractionCDC25C interactions

CCNB2 INPP5E SIPA1L1 SRSF12

2.30e-04156394int:CDC25C
InteractionNAT8L interactions

FAT3 PRNP

2.38e-0412392int:NAT8L
InteractionRASAL2 interactions

INPP5E SIPA1L1 PRNP SRSF12

2.42e-04158394int:RASAL2
InteractionKRT73 interactions

MKI67 NPHP4 CCNB2

2.57e-0464393int:KRT73
InteractionZBTB21 interactions

INPP5E SIPA1L1 PRNP SRSF12

2.60e-04161394int:ZBTB21
InteractionCRABP1 interactions

PRNP CFTR

2.81e-0413392int:CRABP1
InteractionSTARD13 interactions

DMD INPP5E SIPA1L1

3.08e-0468393int:STARD13
InteractionCAMSAP2 interactions

CKAP2 INPP5E SIPA1L1 SRSF12

3.12e-04169394int:CAMSAP2
GeneFamilyTEA domain transcription factors

TEAD2 TEAD1 TEAD4 TEAD3

1.04e-1143441183
GeneFamilyPDZ domain containing

SHROOM4 RIMS1 SIPA1L1

2.88e-031523431220
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

MKI67 LRP1 TEAD2 CKAP2 TEAD3 TSHZ2 ASXL3 FAT3 DNMT3A

1.11e-05777409gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000

HIPK2 CNTN4 KCNQ2 ZNF518B TEAD1 ASXL3 FAT3 SIPA1L1 CFTR

1.67e-05818409gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

LRP1 ZNF518B TSHZ2 ASXL3 FAT3 DNMT3A

3.72e-05337406gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000

LRP1 CNTN4 TEAD3 KIF27 TSHZ2 ASXL3 FAT3 DNMT3A

1.01e-04797408gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000

CNTN4 KCNQ2 RERG ZNF518B TEAD1 ASXL3 FAT3 CFTR

1.21e-04818408DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_1000

HIPK2 GON4L CNTN4 RERG CKAP2 TSHZ2 ASXL3 PRNP

1.41e-04837408gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000
CoexpressionAtlaskidney_P1_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_100

FAT3 CFTR

1.54e-0410402gudmap_kidney_P1_CapMes_Crym_k2_100
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

ST6GALNAC1 RERG RIMS1 TSHZ2 CFTR DNMT3A

3.00e-0819742678ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MKI67 KCNQ2 CKAP2 TEAD1 CCNB2 FAT3

3.10e-081984267225a6194c52b01c581e58d3cda107c4af96dc4f
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

CNTN4 RERG RIMS1 DMD FAT3

4.21e-0716142547b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 CKAP2 NPHP4 CCNB2 SRSF12

5.84e-07172425e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 CNTN4 ZNF518B CKAP2 CCNB2

6.19e-071744251779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ST6GALNAC1 MKI67 RIMS1 CKAP2 CCNB2

6.19e-071744257b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MKI67 CKAP2 NPHP4 CCNB2 SRSF12

6.55e-07176425b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 RIMS1 DMD TSHZ2 FAT3

7.94e-071834257eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

HIPK2 CNTN4 RERG DMD FAT3

7.94e-07183425cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNQ2 DMD ASXL3 FAT3 CFTR

8.15e-07184425ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNQ2 DMD ASXL3 FAT3 CFTR

8.15e-071844252cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNQ2 DMD ASXL3 FAT3 CFTR

8.15e-071844252b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellMild_COVID-19-Epithelial-AT1/AT2|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CNTN4 RERG TEAD2 TEAD4 CFTR

8.37e-07185425c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

CNTN4 RERG RIMS1 DMD FAT3

9.06e-0718842534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CNTN4 RERG RIMS1 DMD FAT3

9.30e-071894256b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MKI67 CNTN4 RIMS1 CKAP2 CCNB2

1.06e-061944257a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCellPCW_07-8.5|World / Celltypes from embryonic and fetal-stage human lung

MKI67 CNTN4 ZNF518B RIMS1 CKAP2

1.06e-061944255759c83308df017f1faae248e9b85388e25254f0
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|COVID-19 / Condition, Lineage and Cell class

ST6GALNAC1 RERG RIMS1 TSHZ2 CFTR

1.11e-06196425dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

LRP1 RERG RIMS1 DMD TSHZ2

1.23e-06200425a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MKI67 KCNQ2 CKAP2 CCNB2

1.27e-05152424f748ee34167f79ecda116aa1914afab47403385a
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

RIMS1 DMD ANKFN1 FAT3

1.51e-051594245335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 TEAD4 FAT3 CFTR

1.55e-05160424c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 TEAD4 FAT3 CFTR

1.55e-0516042425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 ZNF518B CKAP2 CCNB2

1.75e-0516542496f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 CKAP2 NPHP4 CCNB2

1.88e-0516842452fd65024af8683db11d931f7563cbe8eb815d1c
ToppCellNS-critical-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RERG TEAD2 FAT3 CFTR

1.88e-051684246a233045638cb83dab64789b996b7598c325001e
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 CLINT1 CKAP2 CCNB2

1.92e-051694244db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCellClub_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

ST6GALNAC1 RIMS1 TSHZ2 ASXL3

1.92e-0516942403b303af8a26c6ff196507fe24f5bd3d75d7b1af
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 CNTN4 DMD FAT3

1.97e-051704245570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 NPHP4 MAZ CFTR

2.11e-05173424a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 NPHP4 MAZ CFTR

2.11e-05173424639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

ST6GALNAC1 RIMS1 ASXL3 CFTR

2.16e-051744247d2f802f493f19a068e097b2909a9000e2160266
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 RERG CLINT1 RIMS1

2.16e-0517442442f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 CNTN4 CKAP2 CCNB2

2.31e-051774244197cf2b1e743230c821f422836fa5991b155a52
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIPK2 CNTN4 TSHZ2 FAT3

2.31e-05177424da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MKI67 RERG TSHZ2 CCNB2

2.36e-051784247975bf0a3146ee0efa4f547af5977e6bf0ba71fd
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MKI67 CKAP2 CCNB2 MAZ

2.41e-051794246718cadcc2d3b64717ed84244ef1242d392662dc
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 RIMS1 DMD TSHZ2

2.41e-0517942402c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellP15-Endothelial-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MKI67 CKAP2 NPHP4 CCNB2

2.52e-051814240c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 RERG TSHZ2 EFCAB13

2.52e-051814245f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellP15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MKI67 CKAP2 NPHP4 CCNB2

2.52e-05181424f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

MKI67 FGF8 CKAP2 CCNB2

2.52e-05181424be4f35c9eb5b3083acb2264128f095fac1f3da45
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 RERG TSHZ2 EFCAB13

2.52e-05181424c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MKI67 KCNQ2 CKAP2 CCNB2

2.52e-05181424f2ebeb4941510c4b6e50f2379c574d1778d6ced1
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating-Lymphatic_EC_proliferating_L.2.5.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MKI67 CKAP2 TEAD4 CCNB2

2.57e-05182424f703963b5d1e8c1f95d78807521048553b0792d8
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 RERG CKAP2 CCNB2

2.57e-05182424c84f44391932080df31c8765e363c3dff64b2bd1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RERG DMD TSHZ2 ANKFN1

2.57e-0518242444764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RERG DMD TSHZ2 ANKFN1

2.57e-05182424d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MKI67 CKAP2 TEAD4 CCNB2

2.57e-05182424ebd177ad5eac51bf2db0657596618bdf1e5d46e1
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

CNTN4 RERG DMD FAT3

2.63e-05183424818fd886e0188091310825f9145fa53328f2c979
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RERG TEAD2 FAT3 CFTR

2.63e-05183424ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCellCOVID-19-Heart-Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

HIPK2 CNTN4 RERG RIMS1

2.68e-0518442421790cdfa3b4036ad413fd44b94e31563116f25f
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

SHROOM4 CNTN4 ZNF518B TSHZ2

2.68e-0518442467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 CLINT1 RIMS1 TSHZ2

2.68e-0518442401c19a830348ab0b9c02c1546a439de70ee10f97
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 RIMS1 DMD TSHZ2

2.74e-051854243b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellCOPD-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

SHROOM4 TEAD2 TEAD4 TSHZ2

2.74e-051854244abe04198ab5047c211f8d09cdb9650fa52a3cd6
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic|bone_marrow / Manually curated celltypes from each tissue

MKI67 RERG TEAD1 CCNB2

2.74e-051854249d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 RERG TSHZ2 EFCAB13

2.74e-0518542434fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 RERG TSHZ2 EFCAB13

2.74e-051854248816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 CKAP2 NPHP4 CCNB2

2.80e-05186424ec6d0c29e196e374baa96dd3d506f489c959e77e
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 CKAP2 NPHP4 CCNB2

2.80e-051864243993f1ef8a33b8a75dfd3db8d4845b5afbb0bb3d
ToppCellCOPD-Endothelial-VE_Peribronchial|COPD / Disease state, Lineage and Cell class

SHROOM4 TEAD2 TEAD4 TSHZ2

2.80e-0518642423c7d0e8372a71546d687278b985f761d282f92f
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

RERG DMD TSHZ2 FAT3

2.86e-05187424bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MKI67 KCNQ2 CKAP2 CCNB2

2.92e-0518842433afe31b1093d317dc38c324197c6e91bf6c39d3
ToppCellControl-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

SHROOM4 TEAD2 TEAD4 TSHZ2

2.98e-05189424c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

ST6GALNAC1 CNTN4 RIMS1 CFTR

2.98e-0518942484d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MKI67 CKAP2 TSHZ2 CCNB2

2.98e-05189424d049f33115610bda4489968759f754730698b9cd
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 CNTN4 TSHZ2 FAT3

2.98e-051894242a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CNTN4 RERG TSHZ2

2.98e-05189424c734e5693808a0333139e87bd5be2597a9252afe
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CNTN4 RERG TSHZ2

3.04e-05190424445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CNTN4 RERG TSHZ2

3.04e-051904242e592323085ba9c019d678ac2a784462ab470ed9
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 CLINT1 RIMS1 TSHZ2

3.04e-051904243c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 CLINT1 RIMS1 TSHZ2

3.04e-0519042423f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CNTN4 RERG TSHZ2

3.10e-05191424cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 DMD TSHZ2 FAT3

3.10e-05191424107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 DMD TSHZ2 ANKFN1

3.10e-05191424a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MKI67 CLINT1 TEAD1 CCNB2

3.10e-05191424588015d76b68488da6aa6603777682f3d81592bf
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CNTN4 RERG TSHZ2

3.10e-05191424c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 DMD TSHZ2 FAT3

3.10e-05191424bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CNTN4 RERG TSHZ2

3.10e-051914241caf726bd07fdca389e678fc16304a6ef1790423
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 DMD TSHZ2 ANKFN1

3.10e-051914248f6d592edc32fdb901af30501d4360512334e8c2
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CNTN4 RERG TSHZ2

3.10e-051914243d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CNTN4 RERG TSHZ2

3.10e-05191424806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 RERG DMD TSHZ2

3.17e-05192424bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 RERG DMD TSHZ2

3.17e-051924240ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 CNTN4 ASXL3 FAT3

3.23e-05193424fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellLA|World / Chamber and Cluster_Paper

LRP1 CNTN4 RERG TSHZ2

3.23e-05193424d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

ST6GALNAC1 CNTN4 RIMS1 CFTR

3.23e-051934242bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MKI67 KCNQ2 CKAP2 CCNB2

3.23e-05193424ecbe1bd16df547427da5e69a3017300e766c2899
ToppCelldroplet-Tongue-nan-3m-Epithelial-proliferating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 CKAP2 CCNB2 MAZ

3.30e-051944242cac1b9c4da01faaec9a67ec06f47a7060760225
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ST6GALNAC1 RIMS1 TSHZ2 ASXL3

3.30e-05194424e0228f593c3493175962a4817500d4337ddc4e88
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 KCNQ2 TEAD1 FAT3

3.30e-051944248b81f039f5b25d35a4d5a41b27d4d9360ba22f15
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 CNTN4 DMD FAT3

3.30e-051944246e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellNS-critical-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ST6GALNAC1 RERG RIMS1 TSHZ2

3.30e-051944242172d951896265243d14996eacce5aab5e14e26e
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MKI67 CKAP2 TSHZ2 CCNB2

3.30e-05194424d840c1949c328779426c9172e02da09e968f0567
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 CNTN4 ASXL3 FAT3

3.30e-0519442489b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 HIPK2 CLINT1 RIMS1

3.37e-051954243f8ed20ad17afe1545e574e5ca5fe33c3704c7f3
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-proliferating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 CKAP2 CCNB2 MAZ

3.37e-05195424b57132802cb977551e214880984f3edcd375474f
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MKI67 KCNQ2 CKAP2 CCNB2

3.43e-051964244924a36a81d62863c1004b8c76f8096a1f89c548
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST6GALNAC1 HIPK2 CLINT1 RIMS1

3.43e-051964242c3fbfbb08cd327cd97b3fa5a6f83b6d50771fb7
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

MKI67 CKAP2 CCNB2

2.41e-0449273GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CELL_CYCLE
ComputationalNeighborhood of CENPF

MKI67 CKAP2 CCNB2

4.84e-0462273GNF2_CENPF
ComputationalNeighborhood of CDC2

MKI67 CKAP2 CCNB2

4.84e-0462273GNF2_CDC2
Drugmethyl vinyl ketone

TEAD2 CKAP2 FMN1

7.05e-0621413CID000006570
DrugAC1NSGRQ

ABCB5 CFTR

9.48e-063412CID005333904
Drug2,4,4'-trichlorobiphenyl

MKI67 CNTN4 KCNQ2 TEAD2 RIMS1 CKAP2 DMD TSHZ2 CCNB2 ASXL3 FAT3

2.79e-0514114111ctd:C081766
Drug2,4,5,2',5'-pentachlorobiphenyl

MKI67 CNTN4 KCNQ2 TEAD2 RIMS1 CKAP2 DMD TSHZ2 CCNB2 ASXL3 FAT3

3.39e-0514414111ctd:C009828
DrugMcat

TEAD1 TEAD4 TEAD3

3.41e-0535413CID003080785
Drugvinyl carbamate

CKAP2 CCNB2 DNMT3A

4.38e-0538413CID000027492
DrugSolutol HS 15

CLINT1 ABCB5

4.72e-056412CID000124898
Drugaminoanthraquinone

TEAD2 CKAP2

4.72e-056412CID000008341
DiseaseGrowth Disorders

CNTN4 AFF4 DNMT3A

1.60e-0536403C0018273
Diseasecystic fibrosis (implicated_via_orthology)

ABCB5 CFTR

6.41e-059402DOID:1485 (implicated_via_orthology)
DiseaseFacies

AFF4 DNMT3A

8.01e-0510402C0282631
Diseaseprostatic hypertrophy (is_marker_for)

FGF8 CFTR

9.78e-0511402DOID:11132 (is_marker_for)
Diseaseuric acid measurement

CNTN4 RERG ZNF518B FMN1 FAT3 EFCAB13

1.61e-04610406EFO_0004761
DiseaseNeurodevelopmental Disorders

KCNQ2 RIMS1 ASXL3

2.75e-0493403C1535926
DiseaseColorectal Carcinoma

MKI67 LRP1 CNTN4 DMD ABCB5 CFTR

3.42e-04702406C0009402
Diseasediabetes mellitus (implicated_via_orthology)

LRP1 CFTR

5.70e-0426402DOID:9351 (implicated_via_orthology)
DiseaseChild Development Disorders, Specific

CNTN4 KCNQ2

7.11e-0429402C0085997
DiseaseChild Development Deviations

CNTN4 KCNQ2

7.11e-0429402C0085996
DiseaseDevelopmental Disabilities

CNTN4 KCNQ2

7.61e-0430402C0008073
DiseaseMental Retardation, Psychosocial

GON4L INPP5E DNMT3A

8.90e-04139403C0025363
DiseaseProfound Mental Retardation

GON4L INPP5E DNMT3A

8.90e-04139403C0020796
DiseaseMental deficiency

GON4L INPP5E DNMT3A

8.90e-04139403C0917816
Diseaseurate measurement

LRP1 GON4L RERG PTPN9 ZNF518B FMN1

1.22e-03895406EFO_0004531
DiseaseCraniofacial Abnormalities

CNTN4 FGF8 DNMT3A

1.24e-03156403C0376634
Diseaselung cancer (is_marker_for)

MKI67 DNMT3A

1.29e-0339402DOID:1324 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
SGTRVRIKKTNSTFN

C2orf16

991

Q68DN1
QNIHRKTTASTRKVS

CFTR

781

P13569
RTITTRSNSIKQGKD

DNMT3A

831

Q9Y6K1
TQHRNTSKKAQIIGS

ABCB5

906

Q2M3G0
KLRSKVTNSVQVITH

CCDC96

431

Q2M329
RKIRTVGNQTSTKIT

CNTN4

851

Q8IWV2
QQSSGRIDIIHSKKT

DMD

2046

P11532
RNKTHKQGSTQSRLE

ASXL3

921

Q9C0F0
AQSDSTTQRRTVGKK

AFF4

551

Q9UHB7
HSNTRDTVKQGISRT

CKAP2

261

Q8WWK9
LSSQVQRVVKTHSKG

FMN1

336

Q68DA7
QTRVKLTKRSGHTQT

PTPN9

341

P43378
SRKSKQHQSSVRNVS

HIPK2

801

Q9H2X6
TTTRHKRTANPSKTI

CLINT1

271

Q14677
STVTTRIVSQIKTKG

INPP5E

391

Q9NRR6
TKSINRAHKTTGTNK

LRP1

3251

Q07954
TKSHSRLSSQIQVVG

KIF27

1331

Q86VH2
IVKIVRSSSSTGQKN

KCNQ2

686

O43526
VTTTASGKRIRKNHA

MAZ

266

P56270
GKLTQTSGKTTQTHR

MKI67

2016

P46013
TTASTKRHLRTRVQK

MKI67

2716

P46013
TGSSRRKHVVQAQKL

NPHP4

866

O75161
RHSRKSERSSIQKQT

RIMS1

1161

Q86UR5
SERSSIQKQTRKGTA

RIMS1

1166

Q86UR5
SRTSGKHVQVLANKR

FGF8

76

P55075
NSKVKSHVTIRRTVL

CCNB2

21

O95067
SKSGVITLSNHRKQR

FAT3

2446

Q8TDW7
KRRTTVTESLQHKGN

GON4L

6

Q3T8J9
VGRKSLQVQQHSKRT

EFCAB13

86

Q8IY85
HKKVGRRVSQTSNEF

BMP2KL

271

Q5H9B9
KLTLGRSQKHTRAQT

FTH1P19

136

P0C7X4
HNVIKRRNTTTGASA

SIPA1L1

351

O43166
TRKLTASRTVSEKHQ

ST6GALNAC1

171

Q9NSC7
GTHDQSSKERKTRQV

SHROOM4

466

Q9ULL8
TGKTRTRKQVSSHIQ

TEAD2

91

Q15562
QKQTSSGTKSRSHGR

SRSF12

201

Q8WXF0
KTRRRSSTTHVKQAI

RERG

176

Q96A58
QTTGRKQSVSRSLKH

ANKFN1

411

Q8N957
TGKTRTRKQVSSHIQ

TEAD3

81

Q99594
STKQITFIRIHKGSQ

ZNF274

491

Q96GC6
NITIKQHTVTTTTKG

PRNP

181

P04156
KTRTRKQVSSHIQVL

TEAD4

91

Q15561
VSSEVSTLHKRKGRQ

TSHZ2

831

Q9NRE2
TGKTRTRKQVSSHIQ

TEAD1

81

P28347
VHRSKKTNTVRNSGE

ZNF34

216

Q8IZ26
SRSLSISRNKTKQVH

ZNF518B

881

Q9C0D4