Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

EPHB4 ERBB3 ERN1 SCYL1 HUNK PHKA2 MAPK12 MAP3K15 POLR1A POLE2 ADCK1 POLRMT MAGI3 ACVR1C PAPSS2 POLR3A TGFBR1 RNASEL CSNK2A1 CSNK2A2 DGKK PRKCI MAP2K2 CSNK2A3

1.33e-0593819324GO:0016772
GeneOntologyMolecularFunctionkinase activity

EPHB4 ERBB3 ERN1 SCYL1 HUNK PHKA2 MAPK12 MAP3K15 ADCK1 MAGI3 ACVR1C PAPSS2 TGFBR1 RNASEL CSNK2A1 CSNK2A2 DGKK PRKCI MAP2K2 CSNK2A3

5.35e-0576419320GO:0016301
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

EPHB4 ERBB3 ERN1 SCYL1 HUNK PHKA2 MAPK12 MAP3K15 ADCK1 ACVR1C PAPSS2 TGFBR1 RNASEL CSNK2A1 CSNK2A2 DGKK PRKCI MAP2K2 CSNK2A3

6.09e-0570919319GO:0016773
GeneOntologyMolecularFunctionprotein kinase activity

EPHB4 ERBB3 ERN1 SCYL1 HUNK PHKA2 MAPK12 MAP3K15 ADCK1 ACVR1C TGFBR1 RNASEL CSNK2A1 CSNK2A2 PRKCI MAP2K2 CSNK2A3

7.70e-0560019317GO:0004672
GeneOntologyMolecularFunctionRho GDP-dissociation inhibitor activity

ARHGDIA ARHGDIG

2.77e-0431932GO:0005094
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

ERN1 HUNK PHKA2 MAPK12 MAP3K15 ADCK1 ACVR1C TGFBR1 CSNK2A1 CSNK2A2 PRKCI MAP2K2 CSNK2A3

4.17e-0444619313GO:0004674
GeneOntologyBiologicalProcessglucose catabolic process

PGAM2 TIGAR SLC25A12 LRP5 ENO2

1.09e-05321925GO:0006007
GeneOntologyCellularComponentprotein kinase CK2 complex

CSNK2A1 CSNK2A2 CSNK2A3

3.13e-0641943GO:0005956
GeneOntologyCellularComponenttransferase complex, transferring phosphorus-containing groups

ERN1 PHKA2 POLR1A LEO1 POLE2 POLRMT ACVR1C POLR3A TGFBR1 CSNK2A1 CSNK2A2 PRKCI CSNK2A3

1.59e-0533519413GO:0061695
GeneOntologyCellularComponentserine/threonine protein kinase complex

ERN1 PHKA2 ACVR1C TGFBR1 CSNK2A1 CSNK2A2 PRKCI CSNK2A3

1.12e-041571948GO:1902554
GeneOntologyCellularComponentprotein kinase complex

ERN1 PHKA2 ACVR1C TGFBR1 CSNK2A1 CSNK2A2 PRKCI CSNK2A3

1.94e-041701948GO:1902911
GeneOntologyCellularComponenttransferase complex

ERN1 KDM6B PHKA2 FBXW8 PIGA FBXO39 MED17 USP47 PDSS2 OGT POLR1A LEO1 POLE2 POLRMT ACVR1C POLR3A TGFBR1 CSNK2A1 CSNK2A2 PRKCI CSNK2A3

2.53e-0496319421GO:1990234
DomainProt_kinase_dom

EPHB4 ERBB3 ERN1 SCYL1 HUNK MAPK12 MAP3K15 MARVELD3 ADCK1 ACVR1C TGFBR1 RNASEL CSNK2A1 CSNK2A2 PRKCI MAP2K2 CSNK2A3

1.36e-0548919317IPR000719
DomainKinase-like_dom

EPHB4 ERBB3 ERN1 SCYL1 HUNK DST MAPK12 MAP3K15 ADCK1 ACVR1C TGFBR1 RNASEL CSNK2A1 CSNK2A2 MACF1 PRKCI MAP2K2 CSNK2A3

1.39e-0554219318IPR011009
DomainPROTEIN_KINASE_DOM

EPHB4 ERBB3 ERN1 SCYL1 HUNK MAPK12 MAP3K15 ADCK1 ACVR1C TGFBR1 RNASEL CSNK2A1 CSNK2A2 PRKCI MAP2K2 CSNK2A3

5.60e-0549319316PS50011
DomainCH

IQGAP2 SPTBN5 DST FLNC SPECC1 MACF1

5.61e-05651936SM00033
DomainACTININ_2

SPTBN5 DST FLNC MACF1

8.39e-05231934PS00020
DomainACTININ_1

SPTBN5 DST FLNC MACF1

8.39e-05231934PS00019
DomainActinin_actin-bd_CS

SPTBN5 DST FLNC MACF1

8.39e-05231934IPR001589
DomainCH

IQGAP2 SPTBN5 DST FLNC SPECC1 MACF1

8.53e-05701936PF00307
DomainPROTEIN_KINASE_ATP

EPHB4 ERBB3 ERN1 HUNK MAPK12 MAP3K15 ADCK1 ACVR1C TGFBR1 RNASEL CSNK2A1 CSNK2A2 PRKCI MAP2K2 CSNK2A3

8.89e-0545919315PS00107
Domain-

IQGAP2 SPTBN5 DST FLNC SPECC1 MACF1

9.24e-057119361.10.418.10
DomainPIEZO

PIEZO1 PIEZO2

1.06e-0421932PF15917
DomainPiezo

PIEZO1 PIEZO2

1.06e-0421932IPR027272
DomainPiezo_RRas_bdg

PIEZO1 PIEZO2

1.06e-0421932PF12166
DomainPiezo_RRas-bd_dom

PIEZO1 PIEZO2

1.06e-0421932IPR031334
DomainPiezo_dom

PIEZO1 PIEZO2

1.06e-0421932IPR031805
DomainCH

IQGAP2 SPTBN5 DST FLNC SPECC1 MACF1

1.08e-04731936PS50021
DomainCH-domain

IQGAP2 SPTBN5 DST FLNC SPECC1 MACF1

1.25e-04751936IPR001715
DomainPkinase

ERN1 SCYL1 HUNK MAPK12 MAP3K15 ACVR1C TGFBR1 RNASEL CSNK2A1 CSNK2A2 PRKCI MAP2K2 CSNK2A3

1.73e-0438119313PF00069
DomainRNA_pol_Rpb1_2

POLR1A POLR3A

3.17e-0431932PF00623
DomainRhoGDI_domain

ARHGDIA ARHGDIG

3.17e-0431932IPR024792
DomainRNA_pol_asu

POLR1A POLR3A

3.17e-0431932IPR000722
DomainKEN_dom

ERN1 RNASEL

3.17e-0431932IPR010513
DomainRNA_pol_N

POLR1A POLR3A

3.17e-0431932IPR006592
DomainRho_GDI

ARHGDIA ARHGDIG

3.17e-0431932PF02115
DomainRNA_pol_Rpb1_1

POLR1A POLR3A

3.17e-0431932PF04997
DomainRNA_pol_Rpb1_5

POLR1A POLR3A

3.17e-0431932PF04998
DomainRNA_pol_Rpb1_3

POLR1A POLR3A

3.17e-0431932PF04983
DomainRNA_pol_Rpb1_4

POLR1A POLR3A

3.17e-0431932PF05000
Domain-

ARHGDIA ARHGDIG

3.17e-04319322.70.50.30
DomainRPOLA_N

POLR1A POLR3A

3.17e-0431932SM00663
DomainRNA_pol_Rpb1_4

POLR1A POLR3A

3.17e-0431932IPR007083
DomainRNA_pol_Rpb1_5

POLR1A POLR3A

3.17e-0431932IPR007081
DomainRNA_pol_Rpb1_1

POLR1A POLR3A

3.17e-0431932IPR007080
DomainRibonuc_2-5A

ERN1 RNASEL

3.17e-0431932PF06479
DomainRNA_pol_Rpb1_3

POLR1A POLR3A

3.17e-0431932IPR007066
DomainRho_GDI

ARHGDIA ARHGDIG

3.17e-0431932IPR000406
DomainKEN

ERN1 RNASEL

3.17e-0431932PS51392
DomainS_TKc

ERN1 HUNK MAPK12 MAP3K15 ACVR1C TGFBR1 RNASEL CSNK2A1 CSNK2A2 PRKCI MAP2K2 CSNK2A3

3.71e-0435919312SM00220
DomainNebulin

NEB NRAP

6.29e-0441932PF00880
DomainDUF1736

TMTC2 TMTC4

6.29e-0441932IPR013618
DomainNEBULIN

NEB NRAP

6.29e-0441932PS51216
DomainNEBU

NEB NRAP

6.29e-0441932SM00227
DomainNebulin

NEB NRAP

6.29e-0441932IPR013998
DomainNebulin_repeat

NEB NRAP

6.29e-0441932IPR000900
DomainDUF1736

TMTC2 TMTC4

6.29e-0441932PF08409
DomainPUG

ERN1 RNASEL

1.04e-0351932SM00580
DomainSer/Thr_kinase_AS

ERN1 HUNK MAPK12 MAP3K15 ACVR1C TGFBR1 CSNK2A1 CSNK2A2 PRKCI MAP2K2 CSNK2A3

1.26e-0335719311IPR008271
DomainPROTEIN_KINASE_ST

ERN1 HUNK MAPK12 MAP3K15 ACVR1C TGFBR1 CSNK2A1 CSNK2A2 PRKCI MAP2K2 CSNK2A3

1.40e-0336219311PS00108
Domain-

DST MACF1

1.55e-03619323.90.1290.10
DomainGAR

DST MACF1

1.55e-0361932PS51460
DomainPUB_domain

ERN1 RNASEL

1.55e-0361932IPR018997
DomainGAS2

DST MACF1

1.55e-0361932PF02187
Domain-

DST MACF1

1.55e-03619323.30.920.20
DomainGAS_dom

DST MACF1

1.55e-0361932IPR003108
DomainGAS2

DST MACF1

1.55e-0361932SM00243
DomainSpectrin

SPTBN5 DST MACF1

1.65e-03231933PF00435
DomainPentatricopeptide_repeat

XAB2 POLRMT LRPPRC

1.65e-03231933IPR002885
DomainProtein_kinase_ATP_BS

EPHB4 HUNK MAPK12 MAP3K15 ACVR1C TGFBR1 CSNK2A1 CSNK2A2 PRKCI MAP2K2 CSNK2A3

2.01e-0337919311IPR017441
DomainGS_dom

ACVR1C TGFBR1

2.16e-0371932IPR003605
DomainGS

ACVR1C TGFBR1

2.16e-0371932PS51256
DomainPlectin

DST MACF1

2.16e-0371932PF00681
DomainTGF_beta_GS

ACVR1C TGFBR1

2.16e-0371932PF08515
DomainGS

ACVR1C TGFBR1

2.16e-0371932SM00467
DomainPlectin_repeat

DST MACF1

2.16e-0371932IPR001101
DomainPLEC

DST MACF1

2.16e-0371932SM00250
DomainTPR_8

TMTC2 XAB2 OGT TMTC4

2.18e-03531934PF13181
PathwayREACTOME_SIGNAL_TRANSDUCTION_BY_L1

ITGA9 ITGAV CSNK2A1 CSNK2A2 MAP2K2

1.40e-06191525MM15113
PathwayREACTOME_SIGNAL_TRANSDUCTION_BY_L1

ITGA9 ITGAV CSNK2A1 CSNK2A2 MAP2K2

2.42e-06211525M878
PathwayREACTOME_WNT_MEDIATED_ACTIVATION_OF_DVL

DVL2 CSNK2A1 CSNK2A2

6.62e-0581523M27100
PathwayREACTOME_L1CAM_INTERACTIONS

ITGA9 ITGAV SPTBN5 CSNK2A1 CSNK2A2 MAP2K2

8.98e-05681526MM14968
PathwayREACTOME_WNT_MEDIATED_ACTIVATION_OF_DVL

DVL2 CSNK2A1 CSNK2A2

9.84e-0591523MM14792
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

DDX19A RPL29 STRBP ZNF318 ADAR XAB2 ABCB1 FASN FBXW8 DST UTP20 FLNC MYBBP1A POLR1A IARS1 SHMT2 SPECC1 SLC3A2 KIF7 ARHGDIA LSR LRPPRC RRP9 CSNK2A1 MACF1

8.78e-1010241962524711643
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MAGEA1 DDX19A RPL29 ADAR FASN DST SBF1 BYSL AP1M1 UTP20 PGP FLNC MYBBP1A MRPS28 POLR1A IARS1 POLRMT SHMT2 RFC4 PAPSS2 POLR3A SLC3A2 ARHGDIA NSUN5 LRPPRC ARAP3 SLC25A12 MACF1

3.09e-0913531962829467282
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

STRBP ZNF318 XAB2 FASN DST SBF1 BYSL UTP20 USP47 FLNC MYBBP1A POLR1A POLRMT ARHGDIA LRPPRC RRP9 CSNK2A1 CSNK2A2 MACF1

6.62e-096531961922586326
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

IQGAP2 STRBP ADAR PHKA2 FASN FBXW8 CFDP1 UTP20 USP47 FOXJ1 FLNC OGT IARS1 DVL2 POLRMT KIF7 ORC2 RNASEL SIX5 CHSY3 SPIDR

2.02e-088571962125609649
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

ERBB3 STRBP XAB2 PHKA2 DST SBF1 AP1M1 OGT LEO1 ANGEL1 POLRMT PAPSS2 POLR3A TGFBI GRPEL1 ARAP3 PRKCI PLCH1

3.57e-086501961838777146
Pubmed

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

XAB2 DST SUPT4H1 UTP20 MED17 DOCK2 MYBBP1A POLR1A IARS1 POLRMT OPA1 POLR3A GRPEL1 SLC25A12 PRKCI

5.38e-084541961533226137
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

DDX19A FASN SBF1 PUS7 USP47 FLNC OGT LEO1 POLE2 POLRMT SHMT2 IDE OPA1 SLC3A2 KIF7 LSR LRPPRC ARAP3 CSNK2A1 CSNK2A2 PNMA2

1.73e-079741962128675297
Pubmed

Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II.

CSNK2A1 CSNK2A2 CSNK2A3

1.76e-07319632174700
Pubmed

Phosphorylation of the Spi-B transcription factor reduces its intrinsic stability.

SPIB CSNK2A1 CSNK2A2

1.76e-073196310618498
Pubmed

Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit.

CSNK2A1 CSNK2A2 CSNK2A3

1.76e-07319631766873
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

DST SBF1 MED17 USP47 POLRMT KIF7 LRPPRC SLC25A12 ARID2 IQCB1

3.91e-072121961033853758
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

IQGAP2 ADAR FASN MYBBP1A MRPS28 IARS1 POLRMT RFC4 LRPPRC SLC25A12

5.72e-072211961029991511
Pubmed

Defining the membrane proteome of NK cells.

DDX19A RPL29 ACAA1 LPCAT4 SCYL1 ADAR XAB2 FASN PIGA BYSL AP1M1 MED17 DOCK2 MYBBP1A IARS1 RNF213 OPA1 POLR3A SLC3A2 ORC2 LRPPRC GUSB

8.44e-0711681962219946888
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ITGAV DST SBF1 FCHO2 SPECC1 OPA1 SLC3A2 LSR LRPPRC GUSB MACF1 PRKCI PLCH1

9.09e-074211961336976175
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

MAGEA1 RPL29 STRBP SQLE ADAR XAB2 FASN SUPT4H1 BYSL UTP20 FLNC MYBBP1A SHMT2 RFC4 SLC3A2 NSUN5 LRPPRC RRP9 CSNK2A1 CSNK2A2

9.34e-079891962036424410
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

PSD ASH1L LPCAT4 ZNF318 CACTIN SUPT4H1 OGT ANGEL1 DVL2 POLRMT RNF213 SIPA1 RFC4 OPA1 KIF7 SLC25A12 CSNK2A1 ARID2 CSNK2A2 PNMA2 MACF1

1.55e-0611161962131753913
Pubmed

STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams-Beuren syndrome deletion.

STAG3L1 STAG3L2 STAG3L3

1.75e-065196310698974
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

RPL29 ADAR FASN BYSL MED17 MYBBP1A MRPS28 IARS1 ANGEL1 POLRMT RFC4 OPA1 POLR3A SLC3A2 ORC2 ARHGDIA LRPPRC SLC25A12 CSNK2A1 CSNK2A2 IQCB1 PNMA2 MPHOSPH6

2.12e-0613351962329229926
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

IQGAP2 STRBP ASH1L LPCAT4 ZNF318 NEB PGAM2 ABCB1 FASN DST SCN9A METTL25 FLNC MYBBP1A LEO1 DNAH2 MAGI3 SLC3A2 LRPPRC GRPEL1 SLC25A12 DGKK MACF1 PLCH1

2.27e-0614421962435575683
Pubmed

Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.

ADAR AP1M1 IARS1 RFC4 OPA1 SLC3A2 NSUN5 LSR LRPPRC CSNK2A1 MAP2K2

2.52e-063231961124797263
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

DDX19A RPL29 SPC25 SCYL1 FASN BYSL AP1M1 PUS7 USP47 FLNC OGT LEO1 IARS1 DVL2 SHMT2 IDE RFC4 PAPSS2 GRPEL1 CSNK2A1 CSNK2A2 PNMA2 MACF1 ENO2

2.65e-0614551962422863883
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

DDX19A IQGAP2 STRBP ADAR FASN AP1M1 UTP20 MYBBP1A POLR1A POLRMT SHMT2 RFC4 POLR3A NSUN5 SLC25A12 PRKCI

2.79e-067041961629955894
Pubmed

Colonic hamartoma development by anomalous duplication in Cdx2 knockout mice.

EPO SI GUSB

3.48e-066196310383162
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

RPL29 ACAA1 ASH1L FASN DST DOCK2 ARMT1 FLNC MYBBP1A IARS1 SHMT2 PAPSS2 ZNF169 SLC3A2 ARHGDIA LRPPRC MACF1

3.72e-068071961730575818
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

EPHB4 PIEZO1 CACTIN SBF1 BYSL PUS7 TIGAR MYBBP1A MRPS28 POLE2 DNAJC30 POLRMT SHMT2 SLC3A2 KIF7 LSR LRPPRC GRPEL1 GUSB RRP9 PPP1R15B MACF1 PRKCI PLCH1

3.83e-0614871962433957083
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

EPO RPL29 IQGAP2 CACTIN EHF ARMT1 MYBBP1A OGT IARS1 SHMT2 RFC4 PAPSS2 OPA1 SLC3A2 KPTN ARHGDIA LSR LRPPRC SLC25A12 CSNK2A1 CSNK2A2 PNMA2

3.91e-0612841962217353931
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

DDX19A SCYL1 SPTBN5 DST BYSL MIEF2 USP47 MYBBP1A PDSS2 MRPS28 ANGEL1 POLRMT SHMT2 RNF213 IDE OPA1 POLR3A LRPPRC GRPEL1 SLC25A12 RRP9 ARID2 PPP1R15B PRKCI

4.24e-0614961962432877691
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

CAPN9 EPHB4 ERBB3 STRBP MAPK12 DNAH2 SHMT2 GIPC3 POLR3A GALNT11 CSNK2A1 CSNK2A2 DGKK PRKCI MAP2K2 KLK13

4.42e-067301961634857952
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

SPC25 PGAM2 XAB2 FASN BYSL AP1M1 PGP PUS7 TIGAR MYBBP1A OGT MRPS28 LEO1 IARS1 SHMT2 RFC4 PAPSS2 OPA1 SLC3A2 LRPPRC CSNK2A1 CSNK2A2 MACF1

5.52e-0614151962328515276
Pubmed

Perivascular neurons instruct 3D vascular lattice formation via neurovascular contact.

PIEZO1 PIEZO2 KCNG4

6.07e-067196338733989
Pubmed

Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells.

DVL2 CSNK2A1 CSNK2A2

6.07e-067196310806215
Pubmed

A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1.

CSNK2A1 CSNK2A2 CSNK2A3

6.07e-067196311239457
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

ZMYND19 IQGAP2 VPS45 SCYL1 ITGAV METTL25 FOXJ1 MYBBP1A OGT MRPS28 LEO1 INPP5E IARS1 SHMT2 RFC4 OPA1 KIF7 ARHGDIA LRPPRC CSNK2A1 IQCB1 PRKCI

6.13e-0613211962227173435
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DDX19A RPL29 ADAR FASN BYSL AP1M1 UTP20 MYBBP1A POLR1A IARS1 POLRMT SHMT2 IDE RFC4 OPA1 POLR3A SLC3A2 ARHGDIA LRPPRC RRP9 CSNK2A1 CSNK2A2 PRKCI

6.19e-0614251962330948266
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

RPL29 IQGAP2 INPP4A VPS45 FASN DST SBF1 FLNC MYBBP1A OGT IARS1 SIPA1 SPECC1 OPA1 SLC3A2 ARHGDIA LRPPRC SLC25A12 CSNK2A1 CSNK2A2 MACF1 PLCH1 ENO2

6.63e-0614311962337142655
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RPL29 ADAR XAB2 FASN UTP20 MYBBP1A POLR1A IARS1 POLRMT RFC4 SLC3A2 NSUN5 RRP9 ARID2 CSNK2A2 MPHOSPH6 CSNK2A3

7.01e-068471961735850772
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

ADAR FBXW8 SBF1 USP47 FLNC POLR1A SHMT2 LRPPRC PLCH1

7.43e-06232196925515538
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

SDHAF1 ACAA1 SLC25A30 ABCB1 FASN PDSS2 MRPS28 DNAJC30 ADCK1 POLRMT SHMT2 IDE CPT1B OPA1 LRPPRC GRPEL1 SLC25A12 ABCB8 SLC25A44

8.35e-0610471961918614015
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 DST DENND1B SBF1 SUPT4H1 AP1M1 MRPS28 INPP5E MAGI3 SPECC1 LSR LRPPRC IQCB1 MACF1 PRKCI PLCH1 MAP2K2

8.68e-068611961736931259
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

RPL29 IQGAP2 ADAR PHKA2 FASN DST FLNC MYBBP1A OGT MRPS28 IARS1 SHMT2 RFC4 ARHGDIA LRPPRC CSNK2A1 CSNK2A2 IQCB1 MACF1 ENO2

8.80e-0611491962035446349
Pubmed

Two-hybrid analysis identifies PSMD11, a non-ATPase subunit of the proteasome, as a novel interaction partner of AMP-activated protein kinase.

DST FLNC NRAP LMCD1

9.52e-0624196419616115
Pubmed

p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex.

CSNK2A1 CSNK2A2 CSNK2A3

9.67e-068196312393879
Pubmed

Mapping the Genetic Landscape of Human Cells.

SCYL1 CACTIN MED17 PDSS2 MRPS28 LEO1 IARS1 POLE2 RFC4 OPA1 POLR3A MPHOSPH6

1.09e-054511961230033366
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

ZMYND19 IQGAP2 ASH1L ZNF318 ITGA9 AREL1 SUPT4H1 ARMT1 OGFRL1 MYBBP1A OGT INPP5E ANGEL1 SHMT2 FCHO2 TGFBR1 CSNK2A2 MACF1 NLRP4

1.36e-0510841961911544199
Pubmed

A protein interaction landscape of breast cancer.

TMTC2 FBXW8 DST AP1M1 MYBBP1A POLRMT SIPA1 SPECC1 LRPPRC SLC25A12 RRP9 ARID2 CSNK2A2 MACF1

1.64e-056341961434591612
Pubmed

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.

RPL29 ACAA1 DST MYBBP1A JAKMIP3 POLR3A SLC3A2 LRPPRC CSNK2A1 CSNK2A2

1.94e-053291961034316702
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

DDX19A RPL29 ADAR XAB2 CACTIN FASN AP1M1 MYBBP1A OGT POLR1A IARS1 DVL2 SHMT2 OPA1 ORC2 LRPPRC SLC25A12 RRP9 CSNK2A1 CSNK2A2 MAP2K2

1.95e-0513181962130463901
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

FASN MYBBP1A POLR1A IARS1 DVL2 SLC3A2 LRPPRC MAP2K2

2.07e-05202196824639526
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

ACAA1 SLC25A30 FASN PDSS2 MRPS28 DNAJC30 ADCK1 POLRMT SHMT2 IDE CPT1B OPA1 LRPPRC GRPEL1 SLC25A12 ABCB8 SLC25A44

2.20e-059261961720877624
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RPL29 ZNF318 ADAR XAB2 FASN DST CFDP1 PUS7 MYBBP1A DVL2 SHMT2 RFC4 SLC3A2 ORC2 ARHGDIA ARID2 MACF1

2.45e-059341961733916271
Pubmed

Repression of rRNA transcription by PARIS contributes to Parkinson's disease.

FASN BYSL MYBBP1A MRPS28 IARS1 POLRMT RFC4 LRPPRC SLC25A12

2.62e-05272196925315684
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

RPL29 ADAR PGAM2 AP1M1 FLNC POLR1A LEO1 IARS1 DNAH2 IDE POLR3A ARHGDIA NSUN5 LRP5 MACF1 ENO2

2.75e-058471961635235311
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

IQGAP2 STRBP ADAR BYSL UTP20 MED17 MYBBP1A POLR1A POLRMT RFC4 NSUN5 RRP9 ARID2 IQCB1 MACF1

2.95e-057591961535915203
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

NEB SPTBN5 FASN DOCK2 FLNC OGT RNF213 LRP5

3.13e-05214196822199357
Pubmed

Casein kinase 2 and microtubules control axon initial segment formation.

CSNK2A1 CSNK2A2

3.16e-052196220850541
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

3.16e-052196211002341
Pubmed

Differential expression of PIEZO1 and PIEZO2 mechanosensitive channels in ocular tissues implicates diverse functional roles.

PIEZO1 PIEZO2

3.16e-052196237820892
Pubmed

Protein kinase CK2 is involved in G2 arrest and apoptosis following spindle damage in epithelial cells.

CSNK2A1 CSNK2A2

3.16e-052196211704824
Pubmed

Enzymatic activity with an incomplete catalytic spine: insights from a comparative structural analysis of human CK2α and its paralogous isoform CK2α'.

CSNK2A1 CSNK2A2

3.16e-052196221739153
Pubmed

Uncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitors.

ARHGDIA ARHGDIG

3.16e-052196215513926
Pubmed

Fatty acid synthase inhibits the O-GlcNAcase during oxidative stress.

FASN OGT

3.16e-052196228232487
Pubmed

The role of PIEZO ion channels in the musculoskeletal system.

PIEZO1 PIEZO2

3.16e-052196236717101
Pubmed

RNA editing enzyme ADAR1 governs the circadian expression of P-glycoprotein in human renal cells by regulating alternative splicing of the ABCB1 gene.

ADAR ABCB1

3.16e-052196233781748
Pubmed

Identification of four genomic loci highly related to casein-kinase-2-alpha cDNA and characterization of a casein kinase-2-alpha pseudogene within the mouse genome.

CSNK2A1 CSNK2A2

3.16e-05219621497660
Pubmed

A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel.

PIEZO1 PIEZO2

3.16e-052196232142647
Pubmed

ABCB1 regulation through LRPPRC is influenced by the methylation status of the GC -100 box in its promoter.

ABCB1 LRPPRC

3.16e-052196225089713
Pubmed

LRPPRC contributes to the cisplatin resistance of lung cancer cells by regulating MDR1 expression.

ABCB1 LRPPRC

3.16e-052196233649818
Pubmed

Predominance of CK2α over CK2α' in the mammalian brain.

CSNK2A1 CSNK2A2

3.16e-052196221761202
Pubmed

Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line.

ADAR RNASEL

3.16e-052196228362255
Pubmed

Dual regulation of fatty acid synthase (FASN) expression by O-GlcNAc transferase (OGT) and mTOR pathway in proliferating liver cancer cells.

FASN OGT

3.16e-052196234046694
Pubmed

Partial nuclear localization of a bovine phosphoprotein, BCNT, that includes a region derived from a LINE repetitive sequence in Ruminantia.

CFDP1 CSNK2A1

3.16e-052196210350657
Pubmed

Assignment of casein kinase 2 alpha sequences to two different human chromosomes.

CSNK2A1 CSNK2A3

3.16e-05219621577469
Pubmed

CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo.

CSNK2A1 CSNK2A2

3.16e-052196226598688
Pubmed

Mechanosensitive channels: in touch with Piezo.

PIEZO1 PIEZO2

3.16e-052196221056836
Pubmed

Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection.

CSNK2A1 CSNK2A2

3.16e-052196233363536
Pubmed

Nox2-containing NADPH oxidase and xanthine oxidase are sources of superoxide in mouse trachea.

CYBB XDH

3.16e-052196219076165
Pubmed

Astrocytes in the optic nerve head express putative mechanosensitive channels.

PIEZO1 PIEZO2

3.16e-052196226236150
Pubmed

Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation.

CSNK2A1 CSNK2A2

3.16e-05219627896000
Pubmed

Exploring the dynamics of the ABCB1 membrane transporter P-glycoprotein in the presence of ATP and active/non-active compounds through molecular dynamics simulations.

ABCB1 PGP

3.16e-052196238272384
Pubmed

Axonal and Glial PIEZO1 and PIEZO2 Immunoreactivity in Human Clitoral Krause's Corpuscles.

PIEZO1 PIEZO2

3.16e-052196238928429
Pubmed

A hydrophobic gate in the inner pore helix is the major determinant of inactivation in mechanosensitive Piezo channels.

PIEZO1 PIEZO2

3.16e-052196230628892
Pubmed

Piezo1 ion channel pore properties are dictated by C-terminal region.

PIEZO1 PIEZO2

3.16e-052196226008989
Pubmed

Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels.

PIEZO1 PIEZO2

3.16e-052196220813920
Pubmed

Structural basis of CX-4945 binding to human protein kinase CK2.

CSNK2A1 CSNK2A2

3.16e-052196221093442
Pubmed

Characterization of Rho-GDIgamma and Rho-GDIalpha mRNA in the developing and mature brain with an analysis of mice with targeted deletions of Rho-GDIgamma.

ARHGDIA ARHGDIG

3.16e-052196216054116
Pubmed

Combination therapy and noninvasive imaging with a dual therapeutic vector expressing MDR1 short hairpin RNA and a sodium iodide symporter.

ABCB1 SLC5A5

3.16e-052196218703598
Pubmed

[Feeling the pressure? Identification of two proteins activated by mechanical forces].

PIEZO1 PIEZO2

3.16e-052196221299953
Pubmed

Specific localization of the catalytic subunits of protein kinase CK2 at the centrosomes.

CSNK2A1 CSNK2A2

3.16e-052196212568341
Pubmed

Novel prognostic marker TGFBI affects the migration and invasion function of ovarian cancer cells and activates the integrin αvβ3-PI3K-Akt signaling pathway.

ITGAV TGFBI

3.16e-052196238395907
Pubmed

Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development.

PIEZO1 PIEZO2

3.16e-052196238395992
Pubmed

Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.

CSNK2A1 CSNK2A3

3.16e-052196214646071
Pubmed

Mechanisms of mechanotransduction and physiological roles of PIEZO channels.

PIEZO1 PIEZO2

3.16e-052196239251883
Pubmed

Immunolocalization of the mechanogated ion channels PIEZO1 and PIEZO2 in human and mouse dental pulp and periodontal ligament.

PIEZO1 PIEZO2

3.16e-052196237975162
Pubmed

Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels.

PIEZO1 PIEZO2

3.16e-052196228636944
Pubmed

Identification of a phosphatase activity, toward the phosphopeptide pyroGlu-Asp-Asp-Ser(p)-Asp-Glu-Glu-Asn, in nuclear extract from HL-60 promyelocitic leukaemia cells.

CSNK2A1 CSNK2A2

3.16e-052196210970045
Pubmed

Piezo channels: from structure to function.

PIEZO1 PIEZO2

3.16e-052196225037583
Pubmed

Up-regulated transforming growth factor beta-inducible gene h3 in rheumatoid arthritis mediates adhesion and migration of synoviocytes through alpha v beta3 integrin: Regulation by cytokines.

ITGAV TGFBI

3.16e-052196216947382
Pubmed

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.

CSNK2A1 CSNK2A3

3.16e-052196212860116
Pubmed

Developmental and growth defects in mice with combined deficiency of CK2 catalytic genes.

CSNK2A1 CSNK2A2

3.16e-052196221769451
Pubmed

Nuc-ErbB3 regulates H3K27me3 levels and HMT activity to establish epigenetic repression during peripheral myelination.

ERBB3 KDM6B

3.16e-052196227017927
InteractionRAC1 interactions

CYBB EPHB4 RPL29 IQGAP2 STRBP VPS45 ITGAV FASN DST SBF1 UTP20 DOCK2 RASGRF1 DVL2 FCHO2 SIPA1 SPECC1 SLC3A2 TGFBR1 ARHGDIA ARHGDIG LSR LRPPRC CSNK2A2 IQCB1 LRP5 MACF1 PRKCI MAP2K2

3.43e-07106319329int:RAC1
InteractionCCDC8 interactions

DDX19A ZNF318 FASN FBXW8 DST UTP20 MYBBP1A MRPS28 POLR1A IARS1 DVL2 SPECC1 SLC3A2 KIF7 ARHGDIA LSR LRPPRC CSNK2A1 PNMA2 MACF1

5.28e-0665619320int:CCDC8
Cytoband7q11.23

STAG3L1 STAG3L2 STAG3L3 DNAJC30 NSUN5

6.32e-059719657q11.23
Cytoband17p13.1

MFSD6L KDM6B FBXO39 DVL2 DNAH2

1.60e-04118196517p13.1
Cytoband22q13.33

MAPK12 SBF1 CPT1B

5.79e-0438196322q13.33
CytobandEnsembl 112 genes in cytogenetic band chrXp22

FRMPD4 CLTRN PHKA2 PIGA MAP3K15 EGFL6

7.57e-042501966chrXp22
CytobandEnsembl 112 genes in cytogenetic band chr17p13

MFSD6L SPNS3 KDM6B FBXO39 MYBBP1A DVL2 DNAH2

7.63e-043461967chr17p13
Cytoband2q24

SCN9A SLC25A12

9.72e-041119622q24
CytobandEnsembl 112 genes in cytogenetic band chr7q11

STAG3L1 STAG3L2 STAG3L3 DNAJC30 NSUN5 GUSB

1.15e-032711966chr7q11
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 ITGA9 SCN9A FLNC PIEZO2 ARAP3 LMO2 KCNG4 CHSY3

1.21e-07182196941b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 ITGA9 SCN9A FLNC PIEZO2 ARAP3 LMO2 KCNG4 CHSY3

1.21e-0718219695e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 ITGA9 SCN9A FLNC PIEZO2 ARAP3 LMO2 KCNG4 CHSY3

1.21e-071821969b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO1 ITGA9 DST SCN9A FLNC PIEZO2 LMO2 MACF1

1.27e-061781968ad3de3e03a401dac64431a541899445262246347
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO1 ITGA9 SCN9A FLNC PIEZO2 ARAP3 LMO2 MACF1

1.44e-061811968e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPNS3 DST MGST2 EHF OGFRL1 SPECC1 TGFBI LMO2

2.42e-0619419682210f0755882d8f04edb4c109fb17c3f9149f6f7
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPNS3 DST MGST2 EHF OGFRL1 SPECC1 TGFBI LMO2

2.42e-061941968b16ed97eb6b7b7a220e943474c0d85c141b6e3a5
ToppCellHealthy_donor-cDC|World / disease group, cell group and cell class (v2)

SPNS3 DST MGST2 EHF SCN9A SPECC1 TGFBI LMO2

2.71e-061971968a545fe3a80cd721bf01115bbb645753840ec9f40
ToppCellHealthy-cDC|World / disease group, cell group and cell class

ACAA1 SPNS3 DST MGST2 OGFRL1 SPECC1 TGFBI LMO2

2.82e-0619819688976f8d26cb7ff79f74def138c4bbbb0bc2eaf00
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

EPO ITGA9 DST FCHO2 PIEZO2 PNMA2 ADAP2

6.02e-0615619679a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellsevere_COVID-19-cDC|World / disease group, cell group and cell class (v2)

MGST2 EHF SCN9A TIGAR NUDT7 POLE2 KIF7

6.02e-0615619670a7e18ed8e13261c405eb6b9a183e99d8e1aac37
ToppCellBac-SEP-Myeloid-tDC|Bac-SEP / Disease, Lineage and Cell Type

SPIB SPNS3 SCN9A LMCD1 DNAJC30 GPX7 GLCE

8.69e-0616519678728f927502e56f2768b4224e9111939d3d7815a
ToppCellwk_20-22-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PGAM2 MARVELD3 APLP1 ACVR1C ARHGDIG KLK13 ENO2

1.10e-051711967b7cddb8f726a43fb8a37f3e67a3f722e2178fd7a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPIB INPP4A SQLE SPNS3 PGAM2 RASGRF1 TGFBR1

1.14e-0517219671abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPIB INPP4A SQLE SPNS3 PGAM2 RASGRF1 TGFBR1

1.14e-051721967422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCellTuft-tuft-4|World / Class top

SPIB ITGA9 B4GALT5 PIGA RNASEL SLC25A12 KLK13

1.23e-051741967d6f306ebf66061bf9e9742000bfedce12d277452
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Drd1_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

XAB2 MED17 MIEF2 ANGEL1 ZNF169 ARID2 MAP2K2

1.32e-0517619673c76a5c4ca2b378667cb155fbb9675519572b35d
ToppCellILEUM-inflamed-(3)_pDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CYBB SPIB INPP4A MGST2 SCN9A TGFBI NLRP4

1.32e-051761967b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC25A30 SPNS3 PGP MIEF2 POLR3A ARID2 CD96

1.48e-0517919676bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

EPHB4 SPC25 TMTC2 ITGA9 ABCB1 ARAP3 CCM2L

1.70e-051831967ff95382cfed592190d0636d2b750328471f82e0d
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO1 ITGA9 SCN9A FLNC PIEZO2 LMO2 MACF1

1.89e-05186196720340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Chrna6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPC25 TMTC2 MSTN TGFBR1 C2orf80 KLK13

1.93e-051251966fac8a9bff83abb8976013ff7d2b4ce0b68fbb70a
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

CAPN9 ALS2CL DST WNT9A MAGI3 PAPSS2 CHSY3

1.96e-05187196777f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|normal_Lymph_Node / Location, Cell class and cell subclass

CYBB DST FCHO2 PAPSS2 ARHGEF10L TGFBI ADAP2

2.02e-051881967e83de94a9b47a6a90e98face887eae031a322af6
ToppCellcontrol-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CYBB MGST2 OGFRL1 SHMT2 ARHGEF10L ARAP3 SLC25A44

2.09e-051891967bdfd120900ba58d5e54765f7b576e1f8cc2401bf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PIEZO1 TMTC2 HUNK ABCB1 EHF PAPSS2

2.09e-051891967fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB SPIB STRBP ZNF318 SIPA1 LMO2 MACF1

2.17e-051901967ee7b60cdf93c695ea2d59a170ca8cf4dc93e7eb2
ToppCell(01)_Dendritic_cell|World / immune cells in Peripheral Blood (logTPM normalization)

SPIB SPNS3 DST MGST2 SCN9A SPECC1 TGFBI

2.24e-0519119671f4c8078e1a6cd14937c714330af608caced2acf
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SQLE SPC25 TRPM5 DST RASGRF1 PAPSS2 IGFALS

2.32e-0519219675b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

IQGAP2 SCN9A DOCK2 RNF213 TGFBI SPIDR ADAP2

2.32e-051921967a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SQLE NEB TRPM5 DST APLP1 PAPSS2 IGFALS

2.40e-051931967fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TET2 ZNF491 USP51 SCN9A SPECC1 TGFBI ADAP2

2.48e-05194196758046894446cb250814252a23f60fdd59c114d77
ToppCell(010)_cDC|World / immune cells in Peripheral Blood (logTPM normalization)

SPNS3 DST MGST2 SCN9A SPECC1 TGFBI LMO2

2.56e-0519519674aabb3f5ce70100e4d98d7fa9f8d12e84fb9fe3d
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_9|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ACAA1 DST MGST2 TIGAR SPECC1 TGFBI LMO2

2.56e-051951967dd28c63b53f2a97e3fac127294a465870dc371b3
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_9|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ACAA1 DST MGST2 TIGAR SPECC1 TGFBI LMO2

2.56e-051951967d6ff38535898f90be6719cd5152291f2f4f8a746
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid-Microglia|GW08 / Sample Type, Dataset, Time_group, and Cell type.

CYBB SPNS3 MGST2 DOCK2 RNF213 SIPA1 ADAP2

2.64e-05196196789a0ccd0684777927d99d5fc5b7c498f3f124250
ToppCellPBMC-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPNS3 DST MGST2 OGFRL1 SPECC1 TGFBI LMO2

2.64e-051961967e1f763fa9c11bf5f4d80e79f70f9485724ac23fe
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCB1 MGST2 LMCD1 PAPSS2 LSR CCM2L LMO2

2.64e-051961967889c9fed857f64664ca1f47fcec9fecb15ed103c
ToppCellPBMC-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPNS3 DST MGST2 OGFRL1 SPECC1 TGFBI LMO2

2.64e-051961967d376168e15ec1cf618723259966c76be3698b9b0
ToppCellControl-Myeloid-cDC|Control / Disease group, lineage and cell class

SPNS3 DST MGST2 OGFRL1 SPECC1 TGFBI LMO2

2.64e-05196196785d92bc226cc28384c30991cc4ebb02ec2e3ec99
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid|GW08 / Sample Type, Dataset, Time_group, and Cell type.

CYBB SPNS3 MGST2 DOCK2 RNF213 SIPA1 ADAP2

2.64e-05196196791a8c4798572d6c1f03cef5e8e5464ed0046c7cf
ToppCellPBMC-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPNS3 DST MGST2 OGFRL1 SPECC1 TGFBI LMO2

2.64e-051961967553c22c7d48f3b4f6f2b2f10d6e668c5ebb09e8c
ToppCellPBMC-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPNS3 DST MGST2 OGFRL1 SPECC1 TGFBI LMO2

2.64e-0519619674a9095ba3f6709f88f32bf09184553f4bd211f43
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCB1 MGST2 LMCD1 PAPSS2 LSR CCM2L LMO2

2.73e-051971967e567f91fa398fd306d025dcfe89bd50a60216537
ToppCellmild_COVID-19-cDC|mild_COVID-19 / disease group, cell group and cell class (v2)

SPNS3 DST MGST2 SCN9A SPECC1 TGFBI LMO2

2.73e-05197196744ebd3f967779bb7753fc6dcd9fde6d682f9ccd6
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

EPHB4 SPC25 TMTC2 ITGA9 ABCB1 ARAP3 CCM2L

2.73e-051971967ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellCOVID-19-Myeloid|COVID-19 / group, cell type (main and fine annotations)

CYBB IQGAP2 DOCK2 FCHO2 TGFBI GPCPD1 ADAP2

2.82e-05198196733f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCB1 MGST2 LMCD1 SLC3A2 LSR ARAP3 LMO2

2.82e-0519819670a4626b51ba8b52acbaf616f0ced850079cd7149
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CYBB MGST2 PAPSS2 ARHGEF10L TGFBI LMO2 ADAP2

2.82e-051981967579a22199643440b98e381147779ced630d4ed66
ToppCellCOVID-19-COVID-19_Severe-Myeloid-pDC|COVID-19_Severe / Disease, condition lineage and cell class

SPIB STRBP SPNS3 MGST2 SCN9A KPTN TGFBI

2.82e-051981967033ed362333e1d33f2aeea8da5865d2228d154dc
ToppCellcontrol-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CYBB DST OGFRL1 ARHGEF10L TGFBI LMO2 ADAP2

2.82e-05198196735499a5231818e3432cf69b5c4a58c02f7771db8
ToppCellmild-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CYBB OGFRL1 SPECC1 TGFBI LMO2 GPCPD1 ADAP2

2.91e-051991967d0d286eafe935f9b3aaba5b783e8911251121b4a
ToppCellSepsis-Bac-SEP-Myeloid-tDC|Bac-SEP / Disease, condition lineage and cell class

SPIB SPNS3 SCN9A LMCD1 DNAJC30 GPX7 GLCE

2.91e-051991967a2be40d367338d32348a6906c8475aa3b544a0f7
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Transverse / Region, Cell class and subclass

CYBB ZNF491 SCN9A PAPSS2 ARHGEF10L TGFBI ADAP2

2.91e-051991967facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCellcontrol-HLA-DR+_CD83+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CYBB DST OGFRL1 ARHGEF10L TGFBI LMO2 ADAP2

2.91e-051991967f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYBB IQGAP2 FCHO2 PAPSS2 TGFBI TGFBR1 ADAP2

2.91e-051991967994e885b8d1874006302a081d13f1ee881d64612
ToppCellTransverse-(6)_Macrophage-(61)_LYVE1_Macrophage|Transverse / shred on region, Cell_type, and subtype

CYBB ZNF491 SCN9A PAPSS2 ARHGEF10L TGFBI ADAP2

2.91e-051991967dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCellCOVID-19-COVID-19_Mild-Myeloid-pDC|COVID-19_Mild / Disease, condition lineage and cell class

SPIB STRBP SPNS3 MGST2 SCN9A KPTN TGFBI

2.91e-0519919679de61e5189d907cc969ac3043d68204f70acc0bf
ToppCellmild-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 DST MGST2 SCN9A OGFRL1 SPECC1 LMO2

3.01e-05200196786f585bf9066b179bbcbc703bf43f15da4a07284
ToppCellControl-Control-Myeloid-cDC|Control / Disease, condition lineage and cell class

ACAA1 DST MGST2 OGFRL1 SPECC1 TGFBI LMO2

3.01e-0520019671375d199320feb85ba06e74b10df6521e790addf
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EPHB4 DST RNF213 FCHO2 ARAP3 LMO2 MACF1

3.01e-0520019675c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellCOVID-mono1-|COVID / Condition, Cell_class and T cell subcluster

CYBB DST FCHO2 ARHGEF10L TGFBI LMO2 ADAP2

3.01e-052001967445a1aab962673dcc926c33ce9bed5ede9c41c57
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADAR DST SCN9A RNF213 FCHO2 LMO2 MACF1

3.01e-05200196779e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellmild-Classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CYBB TET2 OGFRL1 TGFBI LMO2 GPCPD1 ADAP2

3.01e-052001967c8b80d4e7f70c66cbbdd0665821bcd5db69c7d35
ToppCellCOVID|World / Condition, Cell_class and T cell subcluster

CYBB OGFRL1 FCHO2 ARHGEF10L TGFBI LMO2 ADAP2

3.01e-05200196704a932fe2431e7886120c219ce666f90d3030a1c
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EPHB4 DST RNF213 FCHO2 ARAP3 LMO2 MACF1

3.01e-05200196772ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellCOVID-mono1|COVID / Condition, Cell_class and T cell subcluster

CYBB DST FCHO2 ARHGEF10L TGFBI LMO2 ADAP2

3.01e-052001967bd002c54305c746c07b7418a2084195e9c852ec5
ToppCellCOVID-19-COVID-19_Severe-Myeloid-cDC|COVID-19_Severe / Disease, condition lineage and cell class

ACAA1 DST MGST2 OGFRL1 SPECC1 TGFBI LMO2

3.01e-052001967e7b808d8ed65343a4345fafb03015fe4f7ce302f
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RPL29 ERBB3 MGST2 MARVELD3 XDH SI LSR

3.01e-0520019674b1ae9f71f0fe998b06fa580885572d1fc1544e2
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

INPP4A ABCB1 RNF213 TGFBR1 DGKK MACF1 CD96

3.01e-052001967f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD4 IQGAP2 INPP4A SCN9A MIEF2 MAGI3

4.63e-051461966ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Myeloid-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHF TRPM1 MAP3K15 SPECC1 RNASEL KLK13

4.63e-05146196669cbe8d4772f8e46a5e1a1cdca0e370308a97b4f
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

ERN1 BYSL MED17 LMCD1 ANGEL1 ADAP2

5.58e-0515119668ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_C|E18.5-samps / Age Group, Lineage, Cell class and subclass

EPO MYOM1 LMCD1 SPECC1 DGKK ADAP2

5.58e-0515119663f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DST MGST2 EHF SCN9A SPECC1 LMO2

6.45e-051551966ab539c04f10276ae919d82b1c75f99a84eb695bf
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DST MGST2 EHF SCN9A SPECC1 LMO2

6.45e-0515519669a27558c457f05808af07190b7a5006b047f1d58
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PSD LMCD1 ACVR1C LSR IQCB1 ENO2

6.69e-05156196684f01419d8c116714e8c8c857c4d153a755b7867
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PSD LMCD1 ACVR1C LSR IQCB1 ENO2

6.69e-0515619662285be9746d0d0f62a488b9c64fa67a834758dd7
ToppCellE18.5-Immune-Immune_Myeloid-DC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IQGAP2 B4GALT5 OGFRL1 FLNC POLR1A GUSB

7.69e-0516019669f1fec2cf565193c73cc3c8a4f0476e57478e3b8
ToppCelldroplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPIB IQGAP2 SPNS3 PGAM2 RASGRF1 LMO2

8.82e-051641966cfe07a1ebed8aecb08d0476db71fe314998d54aa
ToppCelldroplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPIB IQGAP2 SPNS3 PGAM2 RASGRF1 LMO2

8.82e-0516419666d331e74efecb4733d87653f86cd67247be05025
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAA1 SQLE FASN NUDT7 LSR SERPINC1

9.11e-051651966d449a568664a81d9b5538e8f409301448a32ac37
ToppCelldroplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB B4GALT5 MAP3K15 ARHGEF10L TGFBI GPCPD1

9.11e-0516519660fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCelldroplet-Lung-nan-18m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB B4GALT5 MAP3K15 ARHGEF10L TGFBI GPCPD1

9.11e-051651966e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CYBB SPIB ARID5A SCN9A DOCK2 TGFBI

9.11e-0516519668b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CYBB SPIB ARID5A SCN9A DOCK2 TGFBI

9.11e-051651966243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAA1 CLTRN B4GALT5 SLC22A6 PAPSS2 GALNT11

9.42e-0516619668ab18c9d911eb3a9970bba7a769294b0927538f7
ToppCelldroplet-Lung-LUNG-1m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSD CLTRN SPC25 EHF MAP3K15 PUS7

9.74e-051671966e30e7ac8ea4399dc3c1d94fc6b857afc80a7a671
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYOM1 NEB PGAM2 NRAP CPT1B PLCH1

9.74e-051671966d78356bf0c473816dbabaee51984940bd822f84e
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPHB4 LPCAT4 ABCB1 MAPK12 JAKMIP3 CCM2L

9.74e-051671966d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCelldroplet-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAA1 CLTRN B4GALT5 SLC22A6 PAPSS2 GALNT11

1.01e-041681966dd48da83c32d41a62f80cd7e5e5c64e42776fa27
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|368C / Donor, Lineage, Cell class and subclass (all cells)

EPHB4 ITGA9 SCN9A PIEZO2 ARAP3 LRP5

1.01e-041681966a74c8a9e3299183fba31ce3053ef325b5dbcd104
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|368C / Donor, Lineage, Cell class and subclass (all cells)

EPHB4 ITGA9 SCN9A PIEZO2 ARAP3 LRP5

1.01e-041681966dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPIB TRPM5 EHF ARHGEF10L CCM2L KLK13

1.04e-04169196605e12524d68d409fed386ffad233305683b4575b
ToppCelldroplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPIB INPP4A SQLE SPNS3 PGAM2 RASGRF1

1.07e-041701966749144a1a869a6bf9acdd227184319083367dc3f
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

MYOM1 IQGAP2 DOCK2 FLNC NRAP ADAP2

1.07e-0417019664232fe937909f93d3736988c707b8f95ce993398
ToppCellImmune_cells-Dendritic_cells|World / Lineage and Cell class

CYBB SPIB SPNS3 PGAM2 RASGRF1 GPCPD1

1.07e-041701966094dc211d80c89ecb1010855f1fe6eeb71bf0e20
ToppCelldroplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPIB INPP4A SQLE SPNS3 PGAM2 RASGRF1

1.07e-04170196625d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERN1 SPIB INPP4A CNR2 DOCK2 NLRP4

1.11e-041711966af1c93eb75f45c042ea475d93db56e4da207e31f
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CAPN9 ALS2CL FLNC KIF7 LSR LRP5

1.14e-0417219660be41df5d35d818deb7316ac21c9366eb4b7bfd1
DrugGlucose

CYBB CCDC60 RPL29 ERBB3 ERN1 IQGAP2 STRBP HUNK KDM6B ABCB1 FASN PIGA CFDP1 BYSL AP1M1 OGT LEO1 XDH SI IDE FCHO2 OPA1 TGFBI TGFBR1 LSR RNASEL SLC25A12 GUSB ARID2 MAP2K2 ENO2

1.61e-06142019631ctd:D005947
DiseaseMalignant neoplasm of breast

EPHB4 MAGEA1 ERBB3 STRBP ZNF318 ITGA9 ALS2CL ADAR ABCB1 FASN AP1M1 UTP20 CNR2 MRPS28 XDH JAKMIP3 RFC4 SLC5A5 ARHGDIA ARAP3 CSF2 TMTC4 RRP9 ABCB8 MACF1

4.15e-08107419325C0006142
DiseaseHeadache

CFDP1 FGF6 RNF213 MACF1 CHSY3

6.34e-05641935HP_0002315
Diseasechronic obstructive pulmonary disease, coronary artery disease

RSPH6A CFDP1

2.53e-0441932EFO_0000341, EFO_0001645
DiseaseDeep Vein Thrombosis

EPO CSF2 SERPINC1

3.36e-04211933C0149871
DiseaseVenous Thrombosis

EPO CSF2 SERPINC1

3.36e-04211933C0042487
DiseaseMetastatic melanoma

EPHB4 SCYL1 MAP3K15 PRKCI

4.35e-04541934C0278883
DiseaseMalignant neoplasm of skin

ERBB3 TGFBR1 CSNK2A1 CSNK2A2

6.10e-04591934C0007114
DiseaseSkin Neoplasms

ERBB3 TGFBR1 CSNK2A1 CSNK2A2

6.10e-04591934C0037286
DiseaseCongestive heart failure

CYBB MSTN FASN XDH CSF2

7.98e-041101935C0018802
DiseaseHeart failure

CYBB MSTN FASN XDH CSF2

7.98e-041101935C0018801
DiseaseLeft-Sided Heart Failure

CYBB MSTN FASN XDH CSF2

7.98e-041101935C0023212
DiseaseHeart Failure, Right-Sided

CYBB MSTN FASN XDH CSF2

7.98e-041101935C0235527
DiseaseHeart Decompensation

CYBB MSTN FASN XDH CSF2

7.98e-041101935C1961112
DiseaseMyocardial Failure

CYBB MSTN FASN XDH CSF2

7.98e-041101935C1959583
Diseaseperitonitis (biomarker_via_orthology)

XDH GUSB

8.75e-0471932DOID:8283 (biomarker_via_orthology)
DiseaseThrombocytopenia

EPO XDH CSF2

8.88e-04291933C0040034
Diseasemelanoma

MAGEA1 EPO FASN SIPA1 SLC5A5 CSF2 MAP2K2

1.29e-032481937C0025202
Diseasepost-operative acute kidney injury

ARHGEF10L LMO2

1.49e-0391932EFO_0009955
DiseaseThyroid Gland Follicular Adenoma

EPO SLC5A5 CSF2

1.55e-03351933C0151468
DiseaseThyroid Neoplasm

EPO SLC5A5 CSF2

1.82e-03371933C0040136
DiseaseShort Stature, CTCAE

PUS7 IGFALS

1.85e-03101932C2919142
DiseaseShort stature

PUS7 IGFALS

1.85e-03101932C0349588
DiseaseLiver carcinoma

MAGEA1 EPO IQGAP2 CLTRN SPC25 ABCB1 FASN SLC5A5 IGFALS ARID2

1.96e-0350719310C2239176
Diseaseschizophrenia, intelligence, self reported educational attainment

TET2 ERBB3 VPS45 LPCAT4 CACNA1I SHMT2 JAKMIP3 SLC25A12

2.09e-033461938EFO_0004337, EFO_0004784, MONDO_0005090
DiseaseProfound Mental Retardation

INPP4A KDM6B FASN INPP5E KIF7

2.25e-031391935C0020796
DiseaseMental Retardation, Psychosocial

INPP4A KDM6B FASN INPP5E KIF7

2.25e-031391935C0025363
DiseaseMental deficiency

INPP4A KDM6B FASN INPP5E KIF7

2.25e-031391935C0917816
DiseaseMoyamoya disease

CFDP1 WNT9A RNF213

2.28e-03401933MONDO_0016820
DiseaseMammary Carcinoma, Human

EPHB4 ERBB3 ADAR ABCB1 FASN CNR2 MRPS28 SLC5A5 ARHGDIA CSF2

2.52e-0352519310C4704874
DiseaseMammary Neoplasms, Human

EPHB4 ERBB3 ADAR ABCB1 FASN CNR2 MRPS28 SLC5A5 ARHGDIA CSF2

2.52e-0352519310C1257931
DiseaseMammary Neoplasms

EPHB4 ERBB3 ADAR ABCB1 FASN CNR2 MRPS28 SLC5A5 ARHGDIA CSF2

2.59e-0352719310C1458155
DiseasePulmonary Thromboembolisms

EPO XDH

2.69e-03121932C0524702
DiseaseParkinson Disease, Secondary Vascular

ABCB1 CNR2

2.69e-03121932C0751414
DiseaseAtherosclerotic Parkinsonism

ABCB1 CNR2

2.69e-03121932C0751415
DiseasePulmonary Embolism

EPO XDH

2.69e-03121932C0034065
DiseaseSecondary Parkinson Disease

ABCB1 CNR2

2.69e-03121932C0030569
DiseaseMitral valve prolapse, response to surgery

AREL1 LMCD1

2.69e-03121932EFO_0009951, HP_0001634
DiseaseIntellectual Disability

FRMPD4 INPP4A ASH1L KDM6B FASN PUS7 INPP5E KIF7 MACF1

2.85e-034471939C3714756
DiseaseThyroid carcinoma

EPO SLC5A5 CSF2

3.00e-03441933C0549473
DiseaseBreast Carcinoma

EPHB4 ERBB3 ADAR ABCB1 FASN CNR2 MRPS28 SLC5A5 ARHGDIA CSF2

3.00e-0353819310C0678222
DiseaseGastric Adenocarcinoma

EPHB4 ERBB3 ERN1

3.19e-03451933C0278701
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

FLNC LRP5

3.68e-03141932DOID:898 (implicated_via_orthology)
Diseaseglucose measurement

TET2 EPO ERN1 SPC25 CACNA1I MAP3K15 USP47 ACVR1C

3.69e-033801938EFO_0004468
DiseaseKidney Failure, Chronic

CYBB EPO FASN

3.84e-03481933C0022661
Diseasemyocardial infarction (biomarker_via_orthology)

CYBB OPA1 TGFBR1 CSNK2A1 CSNK2A3

4.12e-031601935DOID:5844 (biomarker_via_orthology)
Diseasepulse pressure measurement

EPHB4 TET2 EPO SPC25 ZNF318 KDM6B ITGA9 ARID5A AREL1 FASN DENND1B PXDNL CFDP1 MARVELD3 RNF213 SIPA1 PIEZO2 MAP2K2

4.68e-03139219318EFO_0005763
DiseaseGlycogen storage disease

PGAM2 PHKA2

5.43e-03171932cv:C0017919
DiseaseUremia

EPO TGFBR1

5.43e-03171932C0041948
Diseasenephrotic syndrome (is_marker_for)

IGFALS SERPINC1

6.08e-03181932DOID:1184 (is_marker_for)
Diseasemigraine disorder, systolic blood pressure

CFDP1 RNF213

6.08e-03181932EFO_0006335, MONDO_0005277
Diseasemean corpuscular hemoglobin concentration

IQGAP2 PIEZO1 ZNF318 NEB BYSL CACNA1I MED17 POLR1A FCHO2 SPECC1 LMO2 LRP5 MACF1 ENO2 ADAP2

6.26e-03110519315EFO_0004528

Protein segments in the cluster

PeptideGeneStartEntry
ETLGGKKLRVFVYRN

TGFBI

456

Q15582
AAYRGLLRVALERKG

ALS2CL

726

Q60I27
LILFKGDLNYRKLTG

ARMT1

361

Q9H993
LGFRSLKEISAGRIY

ERBB3

441

P21860
KRVKEYSQRLGAGDL

ADCK1

366

Q86TW2
VGRELTRKKGILLQY

ARHGEF10L

1161

Q9HCE6
VEKLGAYELVTGRRL

ARID5A

96

Q03989
LESLKRYRFGKDAVG

ASH1L

1511

Q9NR48
FDYRLAGDKVGKLRV

EGFL6

466

Q8IUX8
GEFISRKYRLGLFRK

ARAP3

591

Q8WWN8
KKLLGDYIGIRLREN

C2orf80

11

Q0P641
ELVGTGYRLSLIKKR

FCHO2

786

Q0JRZ9
GYRLSLIKKRFATGR

FCHO2

791

Q0JRZ9
IALSKYGRVKRGSKV

FGF6

181

P10767
YANGAARLTALRIKK

ACVR1C

466

Q8NER5
LKNIGKYSECGRRLL

ARID2

1776

Q68CP9
LKGKVLICRNYRGDV

AP1M1

11

Q9BXS5
LLLRRKKPYGAISHG

APLP1

601

P51693
LAREYGGSKRNALLK

SPECC1

956

Q5M775
GLGKLEYLLLSRNRL

IGFALS

456

P35858
LRGLLLRGEAIKYLT

POLE2

16

P56282
AGYAFIKRIKEGSII

GIPC3

131

Q8TF64
AGEKLGKEARSLYER

GLCE

526

O94923
SGKRKVYLLSLLLIG

SERPINC1

11

P01008
CTGLLKLYGDRRKFL

CCM2L

451

Q9NUG4
GRLDYAKLRERIKAG

PDSS2

341

Q86YH6
YALLRKSKERQGLDG

B4GALT5

341

O43286
ALELRDGDKQRYLGK

ENO2

46

P09104
ERREARKYASGLLKA

DVL2

471

O14641
RGLVSLSAKIDRKGY

ARRDC2

181

Q8TBH0
RRKFVLLAREGLLKY

ADAP2

151

Q9NPF8
GRGYFAILREETAKK

CCDC60

66

Q8IWA6
YKALLTRGRALVTLG

CNR2

141

P34972
GKVSIAVLRGLAYLR

MAP2K2

171

P36507
EVGRRLYYKLGRKLC

LMO2

66

P25791
RSGLIFYRKGVKAVD

SHMT2

286

P34897
LGIRSKYASLRKDTL

INPP4A

206

Q96PE3
AKVLVYELLLGKGFR

NSUN5

71

Q96P11
GLKVYLGKHALGRVE

KLK13

81

Q9UKR3
TFGKAGEILTKRLRY

ABCB1

776

P08183
YGARTKEIRSRLLKL

OR52D1

296

Q9H346
ESRDVKGLYKRARAG

PAPSS2

156

O95340
GLLGTKELLQRSYRK

DGKK

896

Q5KSL6
YLRITRILKSLGELG

OGFRL1

236

Q5TC84
SLAAIKNRYKGGIRE

LEO1

586

Q8WVC0
LLRVIGRGSYAKVLL

PRKCI

256

P41743
GRGSYAKVLLVRLKK

PRKCI

261

P41743
GFLLLKYRAREPVTK

MAGEA1

111

P43355
AKLLEGKSRRIAGYT

MAGI3

1306

Q5TCQ9
KVLRKAGLSAGYVDA

LPCAT4

331

Q643R3
RAELRGLKRGASYLV

EPHB4

491

P54760
AGKFDRELYLLGIKR

INPP5E

606

Q9NRR6
YERSRGKLIGAKDVQ

NRAP

826

Q86VF7
KVGYKLHGRTLRPAL

GRPEL1

196

Q9HAV7
RLRDLEGIGKSLKYY

DST

1281

Q03001
SFLDYVRRSLKKLGL

METTL25

506

Q8N6Q8
RTGGKRKEILSALYS

LRP5

266

O75197
DLKKEILINVGGRRY

KCNG4

56

Q8TDN1
RESLVRAGKKIAYQG

KDM6B

1551

O15054
KSYRKRRALLIGSLL

MFSD6L

71

Q8IWD5
GSKILVYSLEAGRRL

FBXW8

411

Q8N3Y1
LLAATLKGKVLGFRY

KPTN

41

Q9Y664
SKTRAAYAEKLRRLG

PGP

71

A6NDG6
YGNISERVELRKKLG

GALNT11

426

Q8NCW6
GKRLDYLNLKGARLT

FBXO39

161

Q8N4B4
TIDARAAGKGDLKLY

FLNC

691

Q14315
YRDSKITRILKDSLG

KIF7

301

Q2M1P5
AGYVKSVLERDKLLR

JAKMIP3

421

Q5VZ66
LDTGKYVGLVRVLAK

LRPPRC

746

P42704
ALLGTKILLKYGERE

NLRP4

431

Q96MN2
LRKVGDKILGDLSYR

MED17

196

Q9NVC6
ETLKSLGRYRLLGKI

PNMA2

41

Q9UL42
LGRYRLLGKIFRKQE

PNMA2

46

Q9UL42
LDDAKARLRKYDIGG

NUDT7

16

P0C024
LTARVKGGDGIRIYK

LMCD1

81

Q9NZU5
TLGRVEDFYRKLKGL

MACF1

5231

Q9UPN3
KYALKRLITGLGVGR

MYBBP1A

71

Q9BQG0
ALYILGDKAQLKGVR

SBF1

1326

O95248
ELRQGLYKVLRLGVK

OR56B2P

306

Q8NGI1
RLLKLRYLILGSAVG

OPA1

96

O60313
DKGIGKVYIFRADRR

ITGA9

271

Q13797
RQKLRKLYGSPGDID

PXDNL

1181

A1KZ92
RGKEGYIERKAFLDR

CFDP1

266

Q9UEE9
LVRKLGRGKYSEVFE

CSNK2A3

41

Q8NEV1
LELYKQGLRGSLTKL

CSF2

76

P04141
RKLKELGVNGLIYDR

GPCPD1

596

Q9NPB8
LVRIGREEGLKALYS

SLC25A30

56

Q5SVS4
NLVKGLLEKLLDYRG

DOCK2

1176

Q92608
DLLRLSYGEAKKAAR

ADAR

1176

P55265
ESLRKYKEALLGRVA

ARHGDIA

46

P52565
DRSLAKYKRVLLGPL

ARHGDIG

66

Q99819
LRKFRTYKGGSVRDL

ERN1

886

O75460
KFLSDLRLYGGRVFK

FRMPD4

411

Q14CM0
LERVDGRRLVYKFGK

EHF

276

Q9NZC4
LGLDQKRRKYVVGEL

GUSB

571

P08236
LRKAKRRALGLYQAL

CACNA1I

446

Q9P0X4
VGRLDRGKSAILYVK

ITGAV

916

P06756
SSVKKRGVLLLGDAY

SQLE

396

Q14534
KRVGNYLIGSRKLGE

HUNK

56

P57058
LRGKLKLYTGEACRT

EPO

176

P01588
YAERLLSGAFKKRRL

FOXJ1

201

Q92949
LAGLKGRLDYLSSLK

SLC3A2

241

P08195
GRLDYLSSLKVKGLV

SLC3A2

246

P08195
TVRKAGRYEITVKLG

AREL1

131

O15033
QLVRKLGRGKYSEVF

CSNK2A2

41

P19784
LVRKLGRGKYSEVFE

CSNK2A1

41

P68400
LGAVLAIKGYRKVRK

MARVELD3

376

Q96A59
ARKRIKNPEGGLYLA

CYBB

156

P04839
SGDLLRIGRKALYSI

IQCB1

196

Q15051
RDGRAKPIDLLAKYI

CACTIN

301

Q8WUQ7
KREYRGLELANGIKV

IDE

61

P14735
LGSATLRRKYDRGLL

DNAJC30

101

Q96LL9
LKLAYAVRGNKLERG

DDX19A

191

Q9NUU7
VNIRGKLVSLEKYRG

GPX7

31

Q96SL4
LRLVGLKKSFYGSTL

FASN

1386

P49327
RKLKRFGANVLTIGY

CAPN9

406

O14815
ARLKRPLKSLDGALY

DENND1B

506

Q6P3S1
KLLVRISGKRVYRDL

DNAH2

761

Q9P225
GLRALTSLLRYAGKK

DNAH2

1976

Q9P225
LKKRRVGDLLASYIP

SCNM1

16

Q9BWG6
VFGYLADRLGRRKVL

SLC22A6

151

Q4U2R8
SKLLRDVYAKDGRVS

POLRMT

371

O00411
RGVREVLSKYRSGKL

BYSL

186

Q13895
KRLIRIKNGILRGVY

CPT1B

41

Q92523
GLIRYISGLLRKKVE

PHKA2

821

P46019
YDGRLLEEAVRKKGS

LSR

586

Q86X29
PKDLKLSDGRLRVGY

OGT

546

O15294
LLKKGGLYAELIRRQ

ABCB8

696

Q9NUT2
TKEDLRYLRLRGGLL

MAP3K15

1276

Q6ZN16
GYSEAAKKRITGFRL

MGST2

96

Q99735
AKKRITGFRLSLGIL

MGST2

101

Q99735
GGYLSSRVLLELLRK

MIEF2

246

Q96C03
IVLYGLGSKRDLLER

ORC2

311

Q13416
PKGVSRKLDRLAYIA

RPL29

86

P47914
KERRVTKAYLALLRG

RPUSD1

91

Q9UJJ7
GEKYQKGTRVRLRLL

MRPS28

131

Q9Y2Q9
GKILGIKRSYLVAEV

RSPH6A

346

Q9H0K4
LLLKDYAKLGAARGQ

UTP20

2161

O75691
GIAYLVKVSEGDLRK

RFC4

226

P35249
LTKFIARYGGRKLER

XAB2

561

Q9HCS7
LNELKRRGKRAYGVV

ACAA1

391

P09110
RLRERKYGVVEGKAL

TIGAR

86

Q9NQ88
LVYRGLTDKVGRVKL

POLR1A

656

O95602
LAKRLYRLDGFRKAD

PSD

561

A5PKW4
IYLKARVEAGGLKEL

SCYL1

101

Q96KG9
RRYETLVGTIGKKFA

MPHOSPH6

116

Q99547
EEGLRNGVYLAKLAK

IQGAP2

66

Q13576
ISKERRYAGLKPGEL

PGAM2

136

P15259
KDGTRYTGIRSLKLD

MSTN

181

O14793
KRCVEGQLLRGLSKY

PUS7

441

Q96PZ0
LEDLGRLVLYVVKKG

RNASEL

521

Q05823
DYARLVKGRIEKTLL

POLR3A

1096

O14802
LRLVKGAKGIRTLLF

SCN9A

1621

Q15858
RGRALGAVDKYRLRK

SIX5

176

Q8N196
LLGDVVRLKGFESYR

SIPA1

366

Q96FS4
KRRGLKYELISETGG

STRBP

521

Q96SI9
LYEAAKVFGLRSRKL

IARS1

1211

P41252
VLSLYRDLLRAGRGK

SDHAF1

11

A6NFY7
ILKRGYINKSETRLG

SI

1756

P14410
FIKILRADGITGLYR

SLC25A44

61

Q96H78
KALKGLYGNRDLTAR

STAG3L1

66

P0CL83
KLARALRNYAKTGEI

SPIB

226

Q01892
GVYSALRALKGREKP

PPP1R15B

101

Q5SWA1
GLLARKDGTRKGYLS

RASGRF1

16

Q13972
GIVRELKSRGVAYKS

SUPT4H1

96

P63272
KVYALRKLAGTLERG

SPTBN5

3161

Q9NRC6
YANGAARLTALRIKK

TGFBR1

476

P36897
RLGLEIRKIYGEKLQ

SPC25

141

Q9HBM1
LYRDGTLKLLGRLSL

ANGEL1

621

Q9UNK9
VLRDLGIFGLYKGAK

SLC25A12

471

O75746
KSRGRLIDFKEIQYG

CHSY3

511

Q70JA7
KVRLSIRTALGDKAY

CLTRN

26

Q9HBJ8
VSRLVYRKGIDLLSG

PIGA

231

P37287
SERAGVGKSLYVKRL

RNF213

1991

Q63HN8
KTRLIKFLSDLRRGG

RNF213

2426

Q63HN8
GTKENYGLLRRKLEL

TMTC4

721

Q5T4D3
KRRKKSVYTVGLRGL

USP51

351

Q70EK9
LGIVRLGRVAGKTKY

ZMYND19

6

Q96E35
STLLKDRVKLGTDYR

CD96

216

P40200
YLGGLREQEKRIKCL

TRPM5

1091

Q9NZQ8
IGVILGAEAARRYKK

SPNS3

321

Q6ZMD2
RKLVIISKGLSLIYG

SLC5A5

381

Q92911
GKYLASGDRSKLILI

RRP9

211

O43818
KVLFTKETAGYLRGR

SPIDR

341

Q14159
LTYGKLLALTGRKSE

TMTC2

681

Q8N394
VDRALYLRKTVLGKV

PIEZO2

2246

Q9H5I5
TIRLGRALKKGEYRV

USP47

1111

Q96K76
KALKGLYGNRDLTAR

STAG3L2

66

P0CL84
KLVSAVVEYGGKRVR

VPS45

421

Q9NRW7
LLAYLRRKLGLSGTK

XDH

26

P47989
LKRGTKGLVRLFYLD

PLCH1

31

Q4KWH8
TLGKYGAEVKLRRLL

TRPM1

216

Q7Z4N2
GKRYKRRLNLDTLLS

ZNF225

686

Q9UK10
EGLRRLLGKYKFRDL

UEVLD

6

Q8IX04
LEGRYRASLLKRGFK

WNT9A

106

O14904
KLYGKALSRLISFRR

ZNF491

246

Q8N8L2
KALKGLYGNRDLTAR

STAG3L3

66

P0CL85
VVDRALYLRKTVLGK

PIEZO1

2016

Q92508
KGKAIRIERVIYTGK

TET2

1171

Q6N021
LLRGTERNREKLKGY

ZNF318

246

Q5VUA4
AVIRGNYRLGLSKKS

ZNF169

211

Q14929
DGRTGAKVAIKKLYR

MAPK12

46

P53778
KVRGLKEGVSYVFRV

MYOM1

1101

P52179
YKRDLELEVKGRGLN

NEB

6011

P20929