Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	interferon receptor activity	IFNGR1 IFNAR1	4.51e-05	5	43	2	GO:0004904
Domain	Fork-head_N	FOXA1 FOXA3	1.55e-05	3	43	2	IPR013638
Domain	Forkhead_N	FOXA1 FOXA3	1.55e-05	3	43	2	PF08430
Domain	Forkhead_box_C	FOXA1 FOXA3	1.55e-05	3	43	2	IPR018533
Domain	HNF_C	FOXA1 FOXA3	1.55e-05	3	43	2	PF09354
Domain	PP2A_B56	PPP2R5D PPP2R5E	5.15e-05	5	43	2	IPR002554
Domain	B56	PPP2R5D PPP2R5E	5.15e-05	5	43	2	PF01603
Domain	FN3_dom	FNDC9 IFNGR1 ROS1 SDK1 IFNAR1	1.14e-04	209	43	5	IPR003961
Domain	TF_fork_head_CS_2	FOXQ1 FOXA1 FOXA3	1.61e-04	46	43	3	IPR030456
Domain	TF_fork_head_CS_1	FOXQ1 FOXA1 FOXA3	1.72e-04	47	43	3	IPR018122
Domain	FORK_HEAD_3	FOXQ1 FOXA1 FOXA3	1.95e-04	49	43	3	PS50039
Domain	FH	FOXQ1 FOXA1 FOXA3	1.95e-04	49	43	3	SM00339
Domain	FORK_HEAD_1	FOXQ1 FOXA1 FOXA3	1.95e-04	49	43	3	PS00657
Domain	FORK_HEAD_2	FOXQ1 FOXA1 FOXA3	1.95e-04	49	43	3	PS00658
Domain	Forkhead	FOXQ1 FOXA1 FOXA3	1.95e-04	49	43	3	PF00250
Domain	Fork_head_dom	FOXQ1 FOXA1 FOXA3	1.95e-04	49	43	3	IPR001766
Domain	Tissue_fac	IFNGR1 IFNAR1	3.37e-04	12	43	2	PF01108
Domain	Tissue_factor	IFNGR1 IFNAR1	3.37e-04	12	43	2	IPR001187
Domain	Crystall	CRYGB CRYGC	5.33e-04	15	43	2	PF00030
Domain	CRYSTALLIN_BETA_GAMMA	CRYGB CRYGC	5.33e-04	15	43	2	PS50915
Domain	Beta/gamma_crystallin	CRYGB CRYGC	5.33e-04	15	43	2	IPR001064
Domain	XTALbg	CRYGB CRYGC	5.33e-04	15	43	2	SM00247
Domain	G_crystallin-rel	CRYGB CRYGC	7.74e-04	18	43	2	IPR011024
Domain	FN3	FNDC9 ROS1 SDK1 IFNAR1	1.11e-03	199	43	4	PS50853
Domain	-	FOXQ1 FOXA1 FOXA3 RFX5	1.56e-03	218	43	4	1.10.10.10
Domain	WHTH_DNA-bd_dom	FOXQ1 FOXA1 FOXA3 RFX5	2.28e-03	242	43	4	IPR011991
Domain	KH_1	FUBP3 KHSRP	3.45e-03	38	43	2	PF00013
Domain	-	FUBP3 KHSRP	3.63e-03	39	43	2	3.30.1370.10
Domain	KH	FUBP3 KHSRP	3.82e-03	40	43	2	SM00322
Domain	KH_dom	FUBP3 KHSRP	3.82e-03	40	43	2	IPR004087
Domain	KH_TYPE_1	FUBP3 KHSRP	4.20e-03	42	43	2	PS50084
Domain	KH_dom_type_1	FUBP3 KHSRP	4.61e-03	44	43	2	IPR004088
Domain	FN3	ROS1 SDK1 IFNAR1	8.82e-03	185	43	3	SM00060
Pubmed	Regulation of lens fiber cell differentiation by transcription factor c-Maf.	CRYGB CRYGC MAF	2.41e-07	10	45	3	10383433
Pubmed	The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.	CRYGB CRYGC MAF	7.29e-07	14	45	3	21998302
Pubmed	Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation.	CRYGB CRYGC MAF	1.63e-06	18	45	3	16162653
Pubmed	Japanese encephalitis virus induces vasodilation and severe lethality in adult and aged AG129 mice lacking alpha, beta and gamma interferon receptors.	IFNGR1 IFNAR1	1.64e-06	2	45	2	35931226
Pubmed	The interdependent, overlapping, and differential roles of type I and II IFNs in the pathogenesis of experimental autoimmune encephalomyelitis.	IFNGR1 IFNAR1	1.64e-06	2	45	2	23960239
Pubmed	A non-mouse-adapted enterovirus 71 (EV71) strain exhibits neurotropism, causing neurological manifestations in a novel mouse model of EV71 infection.	IFNGR1 IFNAR1	1.64e-06	2	45	2	22130542
Pubmed	Feasibility and biological rationale of repurposing sunitinib and erlotinib for dengue treatment.	IFNGR1 IFNAR1	1.64e-06	2	45	2	29753658
Pubmed	The magnitude of dengue virus NS1 protein secretion is strain dependent and does not correlate with severe pathologies in the mouse infection model.	IFNGR1 IFNAR1	1.64e-06	2	45	2	22419801
Pubmed	A Mouse Model of PPRV Infection for Elucidating Protective and Pathological Roles of Immune Cells.	IFNGR1 IFNAR1	1.64e-06	2	45	2	33912160
Pubmed	Negligible contribution of M2634V substitution to ZIKV pathogenesis in AG6 mice revealed by a bacterial promoter activity reduced infectious clone.	IFNGR1 IFNAR1	1.64e-06	2	45	2	30002446
Pubmed	Immune response to mouse mammary tumor virus in mice lacking the alpha/beta interferon or the gamma interferon receptor.	IFNGR1 IFNAR1	1.64e-06	2	45	2	9525580
Pubmed	A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice.	IFNGR1 IFNAR1	1.64e-06	2	45	2	31243154
Pubmed	Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less critical.	IFNGR1 IFNAR1	1.64e-06	2	45	2	14990690
Pubmed	Interferon partly dictates a divergent transcriptional response in poxvirus-infected and bystander inflammatory monocytes.	IFNGR1 IFNAR1	1.64e-06	2	45	2	36417857
Pubmed	In Vivo Imaging with Bioluminescent Enterovirus 71 Allows for Real-Time Visualization of Tissue Tropism and Viral Spread.	IFNGR1 IFNAR1	1.64e-06	2	45	2	27974562
Pubmed	Japanese Encephalitis Virus Vaccination Elicits Cross-Reactive HLA-Class I-Restricted CD8 T Cell Response Against Zika Virus Infection.	IFNGR1 IFNAR1	1.64e-06	2	45	2	33101303
Pubmed	Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2.	IFNGR1 IFNAR1	1.64e-06	2	45	2	20592088
Pubmed	A Targeted Computational Screen of the SWEETLEAD Database Reveals FDA-Approved Compounds with Anti-Dengue Viral Activity.	IFNGR1 IFNAR1	1.64e-06	2	45	2	33173007
Pubmed	Functional interferon system is required for clearance of lassa virus.	IFNGR1 IFNAR1	1.64e-06	2	45	2	22238311
Pubmed	Macrophages from nonobese diabetic mouse have a selective defect in IFN-γ but not IFN-α/β receptor pathway.	IFNGR1 IFNAR1	1.64e-06	2	45	2	22396045
Pubmed	Comparative Histopathologic Lesions of the Male Reproductive Tract during Acute Infection of Zika Virus in AG129 and Ifnar-/- Mice.	IFNGR1 IFNAR1	1.64e-06	2	45	2	29378173
Pubmed	Both viral and host factors contribute to neurovirulence of bovine herpesviruses 1 and 5 in interferon receptor-deficient mice.	IFNGR1 IFNAR1	1.64e-06	2	45	2	15016885
Pubmed	Rotavirus Reprograms Multiple Interferon Receptors and Restricts Their Intestinal Antiviral and Inflammatory Functions.	IFNGR1 IFNAR1	1.64e-06	2	45	2	31896593
Pubmed	Adaptation of enterovirus 71 to adult interferon deficient mice.	IFNGR1 IFNAR1	1.64e-06	2	45	2	23527208
Pubmed	Interferon gamma regulates acute and latent murine cytomegalovirus infection and chronic disease of the great vessels.	IFNGR1 IFNAR1	1.64e-06	2	45	2	9687534
Pubmed	Protection from secondary dengue virus infection in a mouse model reveals the role of serotype cross-reactive B and T cells.	IFNGR1 IFNAR1	1.64e-06	2	45	2	22131327
Pubmed	Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro.	IFNGR1 IFNAR1	1.64e-06	2	45	2	22908290
Pubmed	The viral polymerase inhibitor 2'-C-methylcytidine inhibits Norwalk virus replication and protects against norovirus-induced diarrhea and mortality in a mouse model.	IFNGR1 IFNAR1	1.64e-06	2	45	2	23986582
Pubmed	A Single Mutation in the VP1 of Enterovirus 71 Is Responsible for Increased Virulence and Neurotropism in Adult Interferon-Deficient Mice.	IFNGR1 IFNAR1	1.64e-06	2	45	2	27440896
Pubmed	Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis.	IFNGR1 IFNAR1	1.64e-06	2	45	2	33149141
Pubmed	A lethal murine infection model for dengue virus 3 in AG129 mice deficient in type I and II interferon receptors leads to systemic disease.	IFNGR1 IFNAR1	1.64e-06	2	45	2	25392217
Pubmed	Type I, but not type II, interferon is critical in liver injury induced after ischemia and reperfusion.	IFNGR1 IFNAR1	1.64e-06	2	45	2	17935177
Pubmed	A crystallin mutant cataract with mineral deposits.	CRYGB CRYGC	1.64e-06	2	45	2	37331601
Pubmed	Trafficking and replication patterns reveal splenic macrophages as major targets of dengue virus in mice.	IFNGR1 IFNAR1	1.64e-06	2	45	2	22933295
Pubmed	Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch.	IFNGR1 IFNAR1	1.64e-06	2	45	2	34267374
Pubmed	Consequences of in utero exposure to Zika virus in offspring of AG129 mice.	IFNGR1 IFNAR1	1.64e-06	2	45	2	29925850
Pubmed	Rescue of a recombinant Machupo virus from cloned cDNAs and in vivo characterization in interferon (αβ/γ) receptor double knockout mice.	IFNGR1 IFNAR1	1.64e-06	2	45	2	24284323
Pubmed	Suppression of Drug Resistance in Dengue Virus.	IFNGR1 IFNAR1	1.64e-06	2	45	2	26670386
Pubmed	Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors.	IFNGR1 IFNAR1	1.64e-06	2	45	2	7609046
Pubmed	Gamma interferon (IFN-γ) receptor restricts systemic dengue virus replication and prevents paralysis in IFN-α/β receptor-deficient mice.	IFNGR1 IFNAR1	1.64e-06	2	45	2	22973027
Pubmed	Meningeal lymphatic vessels mediate neurotropic viral drainage from the central nervous system.	IFNGR1 IFNAR1	1.64e-06	2	45	2	35524140
Pubmed	Opposing Roles of FoxA1 and FoxA3 in Intrahepatic Cholangiocarcinoma Progression.	FOXA1 FOXA3	1.64e-06	2	45	2	32151057
Pubmed	A peptide-based viral inactivator inhibits Zika virus infection in pregnant mice and fetuses.	IFNGR1 IFNAR1	1.64e-06	2	45	2	28742068
Pubmed	Dynamic roles of type I and type II IFNs in early infection with Mycobacterium tuberculosis.	IFNGR1 IFNAR1	1.64e-06	2	45	2	22566567
Pubmed	Modified mRNA Vaccines Protect against Zika Virus Infection.	IFNGR1 IFNAR1	1.64e-06	2	45	2	28222903
Pubmed	Protective T-cell-based immunity induced in neonatal mice by a single replicative cycle of herpes simplex virus.	IFNGR1 IFNAR1	1.64e-06	2	45	2	11119576
Pubmed	Type I IFN signaling on both B and CD4 T cells is required for protective antibody response to adenovirus.	IFNGR1 IFNAR1	1.64e-06	2	45	2	17339445
Pubmed	Partial IFN-alpha/beta and IFN-gamma receptor knockout trisomy 16 mouse fetuses show improved growth and cultured neuron viability.	IFNGR1 IFNAR1	1.64e-06	2	45	2	10714556
Pubmed	Functional role of type I and type II interferons in antiviral defense.	IFNGR1 IFNAR1	1.64e-06	2	45	2	8009221
Pubmed	Frequent Zika Virus Sexual Transmission and Prolonged Viral RNA Shedding in an Immunodeficient Mouse Model.	IFNGR1 IFNAR1	1.64e-06	2	45	2	28199846
Pubmed	Immune- and Nonimmune-Compartment-Specific Interferon Responses Are Critical Determinants of Herpes Simplex Virus-Induced Generalized Infections and Acute Liver Failure.	IFNGR1 IFNAR1	1.64e-06	2	45	2	27681121
Pubmed	Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood-stage Plasmodium berghei ANKA.	IFNGR1 IFNAR1	1.64e-06	2	45	2	23780878
Pubmed	A Dengue Virus Type 4 Model of Disseminated Lethal Infection in AG129 Mice.	IFNGR1 IFNAR1	1.64e-06	2	45	2	25938762
Pubmed	Zika Virus Infection in the Ovary Induces a Continuously Elevated Progesterone Level and Compromises Conception in Interferon Alpha/Beta Receptor-Deficient Mice.	IFNGR1 IFNAR1	1.64e-06	2	45	2	34730391
Pubmed	Interferon receptor-deficient mice are susceptible to eschar-associated rickettsiosis.	IFNGR1 IFNAR1	1.64e-06	2	45	2	34423779
Pubmed	Theiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors.	IFNGR1 IFNAR1	1.64e-06	2	45	2	7759999
Pubmed	Mice lacking alpha/beta and gamma interferon receptors are susceptible to junin virus infection.	IFNGR1 IFNAR1	1.64e-06	2	45	2	20926559
Pubmed	Two human gamma-crystallin genes are linked and riddled with Alu-repeats.	CRYGB CRYGC	1.64e-06	2	45	2	4065573
Pubmed	Characterization of a model of lethal dengue virus 2 infection in C57BL/6 mice deficient in the alpha/beta interferon receptor.	IFNGR1 IFNAR1	1.64e-06	2	45	2	22815273
Pubmed	Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2.	IFNGR1 IFNAR1	1.64e-06	2	45	2	38086794
Pubmed	CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion.	IFNGR1 IFNAR1	1.64e-06	2	45	2	16585541
Pubmed	Nucleotide sequence of the rat gamma-crystallin gene region and comparison with an orthologous human region.	CRYGB CRYGC	1.64e-06	2	45	2	2777080
Pubmed	Characterization of a Novel Murine Model to Study Zika Virus.	IFNGR1 IFNAR1	1.64e-06	2	45	2	27022155
Pubmed	Type I interferon signaling limits viral vector priming of CD8+ T cells during initiation of vitiligo and melanoma immunotherapy.	IFNGR1 IFNAR1	4.91e-06	3	45	2	33040466
Pubmed	Abortive and productive infection of CNS cell types following in vivo delivery of VSV.	IFNGR1 IFNAR1	4.91e-06	3	45	2	39159381
Pubmed	Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes.	IFNGR1 IFNAR1	4.91e-06	3	45	2	10562320
Pubmed	Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse.	IFNGR1 IFNAR1	4.91e-06	3	45	2	35476975
Pubmed	Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria.	IFNGR1 IFNAR1	4.91e-06	3	45	2	17312160
Pubmed	A critical function for type I interferons in cancer immunoediting.	IFNGR1 IFNAR1	4.91e-06	3	45	2	15951814
Pubmed	Robust anti-SARS-CoV2 single domain antibodies cross neutralize multiple viruses.	IFNGR1 IFNAR1	4.91e-06	3	45	2	35702569
Pubmed	Genomic sequences of murine gamma B- and gamma C-crystallin-encoding genes: promoter analysis and complete evolutionary pattern of mouse, rat and human gamma-crystallins.	CRYGB CRYGC	4.91e-06	3	45	2	8293998
Pubmed	Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain.	IFNGR1 IFNAR1	4.91e-06	3	45	2	30827680
Pubmed	Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice.	IFNGR1 IFNAR1	4.91e-06	3	45	2	16148142
Pubmed	Depletion of macrophages in mice results in higher dengue virus titers and highlights the role of macrophages for virus control.	IFNGR1 IFNAR1	4.91e-06	3	45	2	19637226
Pubmed	Bioluminescent imaging reveals divergent viral pathogenesis in two strains of Stat1-deficient mice, and in αßγ interferon receptor-deficient mice.	IFNGR1 IFNAR1	4.91e-06	3	45	2	21915277
Pubmed	The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators.	FUBP3 KHSRP	4.91e-06	3	45	2	8940189
Pubmed	The human HNF-3 genes: cloning, partial sequence and mutation screening in patients with impaired glucose homeostasis.	FOXA1 FOXA3	4.91e-06	3	45	2	10899756
Pubmed	Differential effects of the type I interferons alpha4, beta, and epsilon on antiviral activity and vaccine efficacy.	IFNGR1 IFNAR1	4.91e-06	3	45	2	18490714
Pubmed	Interplay between alpha/beta and gamma interferons with B, T, and natural killer cells in the defense against herpes simplex virus type 1.	IFNGR1 IFNAR1	4.91e-06	3	45	2	15047800
Pubmed	In vivo ablation of type I interferon receptor from cardiomyocytes delays coxsackieviral clearance and accelerates myocardial disease.	IFNGR1 IFNAR1	4.91e-06	3	45	2	24574394
Pubmed	Frontline Science: CD40 signaling restricts RNA virus replication in Mϕs, leading to rapid innate immune control of acute virus infection.	IFNGR1 IFNAR1	4.91e-06	3	45	2	32441445
Pubmed	An Immune-CNS Axis Activates Remote Hippocampal Stem Cells Following Spinal Transection Injury.	IFNGR1 IFNAR1	4.91e-06	3	45	2	30618602
Pubmed	Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation.	IFNGR1 IFNAR1	4.91e-06	3	45	2	16920966
Pubmed	Casein Kinase 1α Mediates the Degradation of Receptors for Type I and Type II Interferons Caused by Hemagglutinin of Influenza A Virus.	IFNGR1 IFNAR1	4.91e-06	3	45	2	29343571
Pubmed	Distinct requirements for IFNs and STAT1 in NK cell function.	IFNGR1 IFNAR1	4.91e-06	3	45	2	11034357
Pubmed	FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity.	FOXA1 FOXA3	4.91e-06	3	45	2	33636105
Pubmed	Acute Plasmodium Infection Promotes Interferon-Gamma-Dependent Resistance to Ebola Virus Infection.	IFNGR1 IFNAR1	4.91e-06	3	45	2	32209467
Pubmed	Methylation and carbamylation of human gamma-crystallins.	CRYGB CRYGC	4.91e-06	3	45	2	12876325
Pubmed	Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq.	FOXA1 FOXA3	4.91e-06	3	45	2	19919681
Pubmed	A mouse-passaged dengue virus strain with reduced affinity for heparan sulfate causes severe disease in mice by establishing increased systemic viral loads.	IFNGR1 IFNAR1	4.91e-06	3	45	2	18562532
Pubmed	Protein or amino acid deprivation differentially regulates the hepatic forkhead box protein A (FOXA) genes through an activating transcription factor-4-independent pathway.	FOXA1 FOXA3	4.91e-06	3	45	2	19415718
Pubmed	Interferon function is not required for recovery from a secondary poxvirus infection.	IFNGR1 IFNAR1	4.91e-06	3	45	2	16123129
Pubmed	Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells.	IFNGR1 IFNAR1	4.91e-06	3	45	2	11507186
Pubmed	A mosquito salivary protein promotes flavivirus transmission by activation of autophagy.	IFNGR1 IFNAR1	4.91e-06	3	45	2	31937766
Pubmed	Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head.	FOXA1 FOXA3	4.91e-06	3	45	2	1672118
Pubmed	Alpha/beta interferons regulate murine gammaherpesvirus latent gene expression and reactivation from latency.	IFNGR1 IFNAR1	4.91e-06	3	45	2	16254350
Pubmed	The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distribution.	FOXA1 FOXA3	4.91e-06	3	45	2	8034310
Pubmed	S100A4+ macrophages facilitate zika virus invasion and persistence in the seminiferous tubules via interferon-gamma mediation.	IFNGR1 IFNAR1	4.91e-06	3	45	2	33315931
Pubmed	Assignment of the human genes for hepatocyte nuclear factor 3-alpha, -beta, and -gamma (HNF3A, HNF3B, HNF3G) to 14q12-q13, 20p11, and 19q13.2-q13.4.	FOXA1 FOXA3	4.91e-06	3	45	2	9119385
Pubmed	Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm.	FOXA1 FOXA3	4.91e-06	3	45	2	8187630
Cytoband	11q22.3	GRIK4 PDGFD	8.66e-04	44	45	2	11q22.3
GeneFamily	Interferon receptors	IFNGR1 IFNAR1	2.84e-05	5	31	2	599
GeneFamily	Forkhead boxes	FOXQ1 FOXA1 FOXA3	5.38e-05	43	31	3	508
GeneFamily	Beta-gamma crystallins	CRYGB CRYGC	2.95e-04	15	31	2	1359
GeneFamily	WD repeat domain containing\|Protein phosphatase 2 regulatory subunits	PPP2R5D PPP2R5E	2.95e-04	15	31	2	696
GeneFamily	Fibronectin type III domain containing	FNDC9 ROS1 SDK1	2.55e-03	160	31	3	555
Coexpression	GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_UP	IFNGR1 RUNX2 FOXA1 NSMAF USP24	2.29e-05	199	45	5	M5687
Coexpression	GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_DN	TRPM6 TTC39B RUNX2 NSMAF MAF	2.35e-05	200	45	5	M7958
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4\|GI_small-bowel / Manually curated celltypes from each tissue	IFNGR1 ABCA1 RUNX2 TRAV38-1 MAF	1.50e-06	194	45	5	4547b57669be5d4f0de55175802ee04372288a6a
ToppCell	Leuk-UTI-Lymphocyte-T_NK-MAIT\|Leuk-UTI / Disease, Lineage and Cell Type	TRPM6 CFAP20DC TRDV2 MAF	1.72e-05	153	45	4	ac3a1d1b5bf6009df818fd757dad7382d95c60dc
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	SORCS2 ABCA1 RUNX2 SDK1	2.48e-05	168	45	4	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	facs-Lung-24m-Epithelial-airway_epithelial-club_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRYGC CHIA FOXQ1 FOXA1	2.66e-05	171	45	4	bd339e482f09a3fa04b086029b94f45205b8a6c5
ToppCell	facs-Lung-24m-Epithelial-airway_epithelial-club_cell-club_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRYGC CHIA FOXQ1 FOXA1	2.66e-05	171	45	4	8ed98f223143bd81d9819e9a420eb9cc81ee6c53
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORCS2 GRIK4 FOXQ1 FOXA1	2.91e-05	175	45	4	9a96794df049d8228fea57c1584c160191d36b56
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC9 SORCS2 GRIK4 ADCY2	3.46e-05	183	45	4	bc24145855bf4d027a8058bf92bc796c10f241bb
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC9 SORCS2 GRIK4 ADCY2	3.46e-05	183	45	4	4c325ee6da070513097a11445ec95b0415ffd8a2
ToppCell	facs-Lung-EPCAM-24m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 CHIA FOXQ1 FOXA1	3.69e-05	186	45	4	3c4994a1a7db06a61da8170e45e06aaef7896592
ToppCell	facs-Lung-EPCAM-24m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 CHIA FOXQ1 FOXA1	3.69e-05	186	45	4	a583d6fc0f1e729f6e9fd18d7b49d6eab9ca32b9
ToppCell	moderate-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ABCA1 RUNX2 ATP6AP2 MAF	4.53e-05	196	45	4	9152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	IFNGR1 ABCA1 ATP6AP2 MAF	4.62e-05	197	45	4	075044c17f1c52008cd3c292c15cbf485b50411e
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17\|GI_small-bowel / Manually curated celltypes from each tissue	IFNGR1 RUNX2 TRAV38-1 MAF	4.71e-05	198	45	4	f4fc0cac858fc6dcd779d7959ccec51f78ea8cc2
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17\|GI_small-bowel / Manually curated celltypes from each tissue	IFNGR1 RUNX2 MIF MAF	4.80e-05	199	45	4	508a6efc11b1b45899a968888865731088cac668
ToppCell	10x3'2.3-week_12-13-Myeloid_macrophage-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ABCA1 ATP6AP2 MIF MAF	4.80e-05	199	45	4	52095bff9861aeb5ba0e17ac571ba99d0e5fa940
ToppCell	10x3'2.3-week_12-13-Myeloid_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ABCA1 ATP6AP2 MIF MAF	4.80e-05	199	45	4	ac2029a023ccad5820d52f19ff9a46feae007c7b
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Tacr3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FNDC9 RUNX2 MAF	1.82e-04	109	45	3	92ab514fd8d6711f55de9671fc80da22b20ad248
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CFAP20DC ADCY2 MAF	4.13e-04	144	45	3	71107275767a0728541a3695715c44874b3e5efc
ToppCell	facs-Marrow-B-cells-24m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIPF ROS1 RUNX2	4.38e-04	147	45	3	9d7e965fe61bd7b31e09c4b2129a5a98c36f4811
ToppCell	facs-Marrow-B-cells-24m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIPF ROS1 RUNX2	4.38e-04	147	45	3	38552953ff65a0fc20bee6ef57dc5885306ad18b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SORCS2 ROS1 SDK1	4.74e-04	151	45	3	f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GRIK4 SDK1 MAF	5.12e-04	155	45	3	3b8def9e8f66511736ea37f259511f7c8b7743af
ToppCell	facs-MAT-Fat-24m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYGC CHIA FOXQ1	5.21e-04	156	45	3	7433c6d4eb4d061844d8979c1e648d8ed56e1073
ToppCell	facs-Heart-LV-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYGC CHIA FOXA3	5.41e-04	158	45	3	12a82230c01de552f12977634c304626e1cd6903
ToppCell	facs-Heart-LV-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYGC CHIA FOXA3	5.41e-04	158	45	3	bd432ecd2524656804e7c2775250e27db7906b70
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ROS1 MIF AHSP	5.82e-04	162	45	3	ed9ee98d6568b0ac2cd3af1d58a17364ff2cfa22
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-3\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	OGFOD1 CFAP20DC KHSRP	5.92e-04	163	45	3	0e8d3c98209fc98b86b841d69051cee9e276d837
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RUNX2 FOXA1 ADCY2	6.25e-04	166	45	3	1df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RUNX2 FOXA1 ADCY2	6.25e-04	166	45	3	9628522e7af8f8edca733588a364ab2454ac5ca5
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUNX2 AQR NSMAF	6.36e-04	167	45	3	e0f2509e86302eca8352821bce12597f6c51fc24
ToppCell	facs-Lung-EPCAM-24m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUNX2 AQR NSMAF	6.36e-04	167	45	3	b25646b6653cd8814dbeae4c74ce899ede105200
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRPM6 FOXA1 SDK1	6.47e-04	168	45	3	6521bead9789d626b86cbd08692c621c5a5aef33
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRPM6 FOXA1 SDK1	6.58e-04	169	45	3	c3ee781735a9288ce1822b230d39bb91c1415589
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA1 FOXA1 MAF	6.69e-04	170	45	3	f664c7559e383b37845c123e41a3be316d869ba0
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA1 FOXA1 MAF	6.69e-04	170	45	3	0272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCell	Control-Epithelial_cells-Airway_basal\|Control / group, cell type (main and fine annotations)	TRPM6 SDK1 ADCY2	6.81e-04	171	45	3	3965ced4be6db14265a90673502fceee425837ca
ToppCell	droplet-Lung-LUNG-1m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 FOXA1 MAF	7.04e-04	173	45	3	69b404e92aad3e6dff67e75466f073f20a71f13f
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FOXA1 SDK1 ADCY2	7.04e-04	173	45	3	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 FOXA1 MAF	7.04e-04	173	45	3	26bba58f9fb215d1d155504906cd77e8774f6936
ToppCell	Basal_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	TRPM6 SDK1 ADCY2	7.16e-04	174	45	3	a0060be3940043015dcc49a5157de5541aed24a1
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFAP20DC CHIA KIAA1549L	7.16e-04	174	45	3	fde40c5d51f5380088360dc5a583eb04e518deb6
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRB3 FOXA1 ADCY2	7.16e-04	174	45	3	a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRPM6 CRNKL1 ADCY2	7.16e-04	174	45	3	3f0a5ce074675d57d479fa069385a1b3071e884e
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRPM6 FOXQ1 FBXW5	7.28e-04	175	45	3	711ace94fa9a763c6ae48171a690953f25deebe4
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	IFNGR1 PDGFD MAF	7.28e-04	175	45	3	16849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GRIK4 FOXQ1 KIAA1549L	7.28e-04	175	45	3	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GRIK4 FOXQ1 KIAA1549L	7.28e-04	175	45	3	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	7.28e-04	175	45	3	9d797888edb39fd12fd9cfc698a42b7bed19a5b5
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-MAIT\|lymph-node_spleen / Manually curated celltypes from each tissue	IFNGR1 RUNX2 MAF	7.40e-04	176	45	3	25c197d3b39deffa4801a1d12cdb54320cbae509
ToppCell	droplet-Lung-LUNG-30m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 CHIA FOXA3	7.40e-04	176	45	3	5201f003192c033655ba47f0faf8c47a96eae03d
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RUNX2 FOXA1 SDK1	7.40e-04	176	45	3	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	7.40e-04	176	45	3	95d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	SORCS2 FOXQ1 RUNX2	7.52e-04	177	45	3	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	10x3'2.3-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ABCA1 ATP6AP2 MAF	7.65e-04	178	45	3	e44b0aa82890ae84fc4d1343f1c65ae2fda69a11
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 CHIA FOXA3	7.65e-04	178	45	3	76e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCell	droplet-Lung-30m-Epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 CHIA FOXA3	7.65e-04	178	45	3	5442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCell	T_cells-TFH-like_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	SDK1 MAF AHSP	7.65e-04	178	45	3	e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 CHIA FOXA3	7.65e-04	178	45	3	82f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRPM6 CHIA FOXA3	7.65e-04	178	45	3	523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SORCS2 ROS1 FOXA1	7.77e-04	179	45	3	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ROS1 FOXA1 ADCY2	7.77e-04	179	45	3	f2e8fc975c30992611630197b79daaeef7c4211d
ToppCell	Epithelial-basal_cell\|World / Lineage, Cell type, age group and donor	TRPM6 FOXA1 SDK1	7.77e-04	179	45	3	d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	7.77e-04	179	45	3	3b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SDK1 ADCY2 PDGFD	7.77e-04	179	45	3	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	CFAP20DC FBXW5 MAF	7.90e-04	180	45	3	81d60f0fa9e3b5bfcec85139a0a49e9130145f0e
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA1 GRIK4 SDK1	7.90e-04	180	45	3	f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	7.90e-04	180	45	3	8f774dcacc1626e4e6492f1eb927b0ed56fbe686
ToppCell	facs-BAT-Fat-24m\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYGC CHIA FOXQ1	7.90e-04	180	45	3	3d4a7fbd407d4433bd7d525f785312e90f9a5eb8
ToppCell	droplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 CHIA FOXA3	8.02e-04	181	45	3	cadb18fc73031eb9f779599e15cd7861337fee78
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	8.02e-04	181	45	3	153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	8.02e-04	181	45	3	bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 CHIA FOXA3	8.02e-04	181	45	3	85bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-club_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LIPF TRPM6 FOXA1	8.02e-04	181	45	3	4a0f1b121570430afb100c589657d931184e124f
ToppCell	lymphoid-NK_cell-TNFRSF18+IL7R+_NK_cell\|World / Lineage, cell class and subclass	GRIK4 PDGFD MAF	8.02e-04	181	45	3	0d096d7d557fd2e71b35e41816e11d7e83cd9210
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-club_cell-club_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LIPF TRPM6 FOXA1	8.02e-04	181	45	3	34b49092f71128898af3b311170c4ed8adfefcff
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	8.02e-04	181	45	3	7704f236831cffe4f2a75d4c461eb88b4177e206
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC9 GABRB3 KIAA1549L	8.15e-04	182	45	3	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	droplet-Lung-nan-21m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 CHIA FOXA1	8.15e-04	182	45	3	40539ade8c3cd12b61f1cd0d493828e58282796b
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC9 GABRB3 KIAA1549L	8.15e-04	182	45	3	6cde859edfe7607bd7ada89d20258413d06f4207
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	8.15e-04	182	45	3	f00eec1f434d92d44787d3d3343476c98c3de5b4
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIPF TRPM6 FOXA1	8.15e-04	182	45	3	f8eb35eb7f2b8ad47d527ae9ff8a9ddbcd2eedce
ToppCell	facs-Lung-EPCAM-18m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIPF TRPM6 FOXA1	8.15e-04	182	45	3	6685a0abd9c3a79d03b6a578e5d7fa86a9d74117
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FOXA1 FOXA3 ADCY2	8.15e-04	182	45	3	dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	IFNGR1 NSMAF	8.21e-04	42	45	2	b0ebd9d2456e4bab44e91b35d728224da6a052ea
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	8.28e-04	183	45	3	5a541a7f6c3514be8a13e988185dfe388c874f8b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	8.28e-04	183	45	3	d2074b13b4831ec18c81273d9a1ff673c3f6a16d
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB3 MIF MAF	8.28e-04	183	45	3	5c4f7d02ba3a3c4a22ac71302e7c9a47e205eef5
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	8.28e-04	183	45	3	04d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	8.42e-04	184	45	3	c4c1a3d279ca733b865ce46570d7642dc137f9a4
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	8.42e-04	184	45	3	2ba98708dfd7f1b2a661578a334684094ff453ad
ToppCell	droplet-Lung-nan-21m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 CHIA FOXA1	8.55e-04	185	45	3	0e7351cd6d6e6e8c29573042e168da50ee496cfc
ToppCell	droplet-Lung-nan-21m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 CHIA FOXA1	8.55e-04	185	45	3	6938ac3cab536cf8a474eba441ce6dcdfcc43b53
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	8.55e-04	185	45	3	e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ROS1 FOXA1 ADCY2	8.55e-04	185	45	3	eb78614c4acf8d2ce7874d7e51e16997b76127ef
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic_-_developing-DN1_thymic_pro-T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IFNGR1 PDGFD MAF	8.55e-04	185	45	3	5db31631a4b4c4bfeb28f02d8dab00a48d77bcba
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP6AP2 CLN3 PDGFD	8.68e-04	186	45	3	39e475a3c167b33daa63b0c1bfa32451c5f46635
ToppCell	IIH-NK\|IIH / Condition, Cell_class and T cell subcluster	GRIK4 TRDV2 PDGFD	8.68e-04	186	45	3	cab1249b849013cf0334f25ee8d840f0521f4eb8
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RUNX2 SDK1 MAF	8.68e-04	186	45	3	948815663c212c4311329d503b5991cbbbff9808
ToppCell	IIH-NK-\|IIH / Condition, Cell_class and T cell subcluster	GRIK4 TRDV2 PDGFD	8.68e-04	186	45	3	2c90b45c8ccfd86bbf6840dba7f0d7f08b5ea914
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SORCS2 ROS1 FOXA1	8.68e-04	186	45	3	2ea5ff14861e5f91d0e6a5767c403a24045d715c
Drug	Vitamine K2	CRYGC RUNX2 MIF	3.71e-06	16	44	3	CID015956540
Drug	1 Jak	IFNGR1 ABCA1 RUNX2 IFNAR1	1.41e-05	76	44	4	CID000446429
Disease	sphingomyelin measurement	TTC39B ABCA1 PPP2R5E FOXA3 SDK1 PCIF1	3.01e-06	278	43	6	EFO_0010118
Disease	kit ligand measurement	ABCA1 PCIF1	6.22e-06	3	43	2	EFO_0010612
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	TTC39B ABCA1 FOXA3 USP24 PCIF1	1.87e-05	225	43	5	EFO_0008317, EFO_0020947
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	TTC39B ABCA1 FOXA3 USP24 PCIF1	4.02e-05	264	43	5	EFO_0008317, EFO_0020944
Disease	coiled-coil domain-containing protein 126 measurement	ABCA1 PCIF1	4.34e-05	7	43	2	EFO_0801482
Disease	proactivator polypeptide-like 1 measurement	SORCS2 PCIF1	4.34e-05	7	43	2	EFO_0801912
Disease	apolipoprotein B measurement	SORCS2 TTC39B PDGFD NSMAF MAF USP24 PCIF1	4.47e-05	663	43	7	EFO_0004615
Disease	Hepatic fibrosis	SORCS2 KIAA1549L SDK1	5.07e-05	49	43	3	HP_0001395
Disease	free cholesterol to total lipids in small HDL percentage	TTC39B ABCA1 PCIF1	5.72e-05	51	43	3	EFO_0022285
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	TTC39B ABCA1 FOXA3 USP24 PCIF1	6.38e-05	291	43	5	EFO_0008317, EFO_0020946
Disease	cognitive decline measurement	IFNGR1 CRYGC ABCA1 SDK1 ADCY2 MAF	7.04e-05	486	43	6	EFO_0007710
Disease	free cholesterol to total lipids in very large HDL percentage	TTC39B ABCA1 PCIF1	7.17e-05	55	43	3	EFO_0022288
Disease	CATARACT, COPPOCK-LIKE	CRYGC MAF	7.42e-05	9	43	2	C1852438
Disease	Cataract, Pulverulent	CRYGC MAF	7.42e-05	9	43	2	C1833118
Disease	Cataract microcornea syndrome	CRYGC MAF	7.42e-05	9	43	2	C1861829
Disease	free cholesterol to total lipids in medium HDL percentage	TTC39B ABCA1 PCIF1	9.31e-05	60	43	3	EFO_0022282
Disease	free cholesterol in HDL measurement	TTC39B ABCA1 PCIF1	9.78e-05	61	43	3	EFO_0022264
Disease	phospholipids in HDL measurement	TTC39B ABCA1 PCIF1	9.78e-05	61	43	3	EFO_0022293
Disease	HDL cholesterol change measurement, physical activity	TTC39B ABCA1 PCIF1	1.03e-04	62	43	3	EFO_0003940, EFO_0007805
Disease	total lipids in HDL measurement	TTC39B ABCA1 PCIF1	1.08e-04	63	43	3	EFO_0022307
Disease	anxiety disorder, stress-related disorder	SDK1 ADCY2	1.36e-04	12	43	2	EFO_0006788, EFO_0010098
Disease	phospholipids in large HDL measurement	TTC39B ABCA1 PCIF1	1.67e-04	73	43	3	EFO_0022190
Disease	total lipids in large HDL	TTC39B ABCA1 PCIF1	1.74e-04	74	43	3	EFO_0022189
Disease	cholesterol in large HDL measurement	TTC39B ABCA1 PCIF1	2.19e-04	80	43	3	EFO_0021900
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	TTC39B FOXA3 USP24 PCIF1	3.06e-04	222	43	4	EFO_0008317, EFO_0020943
Disease	caudal middle frontal gyrus volume measurement	NSMAF KHSRP	3.13e-04	18	43	2	EFO_0010290
Disease	phospholipids:total lipids ratio	TTC39B ABCA1 USP24 PCIF1	3.33e-04	227	43	4	EFO_0020946
Disease	inferior parietal cortex volume measurement	CRYGB CRYGC	3.49e-04	19	43	2	EFO_0010307
Disease	triglyceride measurement, alcohol drinking	TTC39B ABCA1 PCIF1	4.10e-04	99	43	3	EFO_0004329, EFO_0004530
Disease	free cholesterol measurement, intermediate density lipoprotein measurement	ABCA1 FOXA3 PCIF1	4.74e-04	104	43	3	EFO_0008591, EFO_0008595
Disease	systemic mastocytosis	TTC39B ABCA1	6.09e-04	25	43	2	MONDO_0016586
Disease	cataract (is_implicated_in)	CRYGC MAF	6.59e-04	26	43	2	DOID:83 (is_implicated_in)
Disease	sleep duration, high density lipoprotein cholesterol measurement	TTC39B ABCA1 PCIF1	7.36e-04	121	43	3	EFO_0004612, EFO_0005271
Disease	esterified cholesterol measurement	TTC39B ABCA1 FOXA3	8.67e-04	128	43	3	EFO_0008589
Disease	choline measurement	TTC39B ABCA1 MAF	9.07e-04	130	43	3	EFO_0010116
Disease	cholesteryl esters to total lipids in large LDL percentage	TTC39B ABCA1	9.39e-04	31	43	2	EFO_0022249
Disease	free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	TTC39B ABCA1 FOXA3 PCIF1	9.81e-04	303	43	4	EFO_0004612, EFO_0020945
Disease	Large cell carcinoma of lung	TRPM6 ROS1	1.00e-03	32	43	2	C0345958
Disease	free cholesterol in small HDL measurement	ABCA1 PCIF1	1.20e-03	35	43	2	EFO_0022270
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	TTC39B ABCA1 PCIF1	1.22e-03	144	43	3	EFO_0004611, EFO_0020943
Disease	low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	TTC39B ABCA1 PCIF1	1.45e-03	153	43	3	EFO_0004611, EFO_0020946
Disease	low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	TTC39B ABCA1 PCIF1	1.45e-03	153	43	3	EFO_0004611, EFO_0020944

Protein segments in the cluster

Peptide	Gene	Start	Entry
ERALYYWNNEYIMSL	PPP2R5E	361	Q16537
EDPWKTNYRMYSYVT	ESD	111	P10768
VEDWMNFYINYYRQQ	AHSP	41	Q9NZD4
SLELQPWMYNEQYTF	ABCA1	1376	O95477
PWMYNEQYTFVSNDA	ABCA1	1381	O95477
GSNAYLNVDYVMNYW	CHIA	236	Q9BZP6
RALYYWNNEYIMSLI	PPP2R5D	421	Q14738
QYLENYLWMNYSPEV	AQR	71	O60306
PSTLSNEEYMYAYRW	RFX5	81	P48382
LYDWINPTYLDMDYQ	OGFOD1	266	Q8N543
AHLEDYYWMTGYPQQ	MAF	86	O75444
YYWMTGYPQQLNPEA	MAF	91	O75444
DYYHIMYRPNWNSIF	FNDC9	26	Q8TBE3
ADMRPYNWSYTQFSQ	FBXW5	131	Q969U6
SQMITYWGYPNEEYE	LIPF	36	P07098
NQNYVLKWDYTYANM	IFNAR1	241	P17181
YFNPESWQEDLENMY	PDGFD	226	Q9GZP0
PDYTMAWAEYYRQQV	FUBP3	541	Q96I24
MYFQQYWRDKRLAYS	GABRB3	86	P28472
QWVPTYRPEMYQYSL	KIAA1549L	1606	Q6ZVL6
YINYYDMNAANVGWN	MIF	96	P14174
IYQWIMDLFPYYRQN	FOXA1	196	P55317
YNIWNMDPGYDSIIY	ATP6AP2	326	O75787
DWLYESYYCMSQQHP	ADCY2	31	Q08462
LPRVNQFWYKYTYME	CRNKL1	306	Q9BZJ0
YYFNRFTNQSLWEMP	PCIF1	61	Q9H4Z3
YFLRRGEYPDYQQWM	CRYGB	56	P07316
SWILYEMPNYRGRQY	CRYGB	131	P07316
YMLQWQRGHLSNYQY	NSMAF	301	Q92636
YLLRRGEYPDYQQWM	CRYGC	56	P07315
NSRYQTYQRMWNYMY	GRIK4	681	Q16099
TYQRMWNYMYSKQPS	GRIK4	686	Q16099
YMSDPTYYNSWKRRA	SDK1	2146	Q7Z5N4
TIESYNMNPIVYWEY	IFNGR1	36	P15260
DNYWMLNPNSEYTFA	FOXQ1	191	Q9C009
QPDYSAAWAEYYRQQ	KHSRP	671	Q92945
PWSYDQSYPSYLSQM	RUNX2	296	Q13950
CWSAYYNSAMNPLIY	TAAR8	296	Q969N4
SEIYQWIMDLFPYYR	FOXA3	141	P55318
VAVQEWYQMDTYNLY	SORCS2	401	Q96PQ0
WYQMDTYNLYQSDPR	SORCS2	406	Q96PQ0
ASEYDWRNYQPSQMS	CFAP20DC	531	Q6ZVT6
AQQYRWYQMLYQAGV	CLN3	316	Q13286
NVFQQNWMQAYYYSD	TTC39B	441	Q5VTQ0
NYYINWYRKTQGNTM	TRDV2	51	A0JD36
VPQSQDFQFMWYYSD	TRPM6	771	Q9BX84
NNLWKYNRYRYIMTY	TRPM6	1081	Q9BX84
NVSDMDWYNNSLYYS	ROS1	706	P08922
MYEEQWSYYDDKQPY	TJP1	1086	Q07157
YWNAYMLFYQRVSDQ	USP24	2031	Q9UPU5
NYYLFWYKQPPSRQM	TRAV38-1	51	A0A0B4J264