Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-7 ERVK-21 ERVK-9 PGC ERVK-18 ERVK-24

4.56e-07371606GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-7 ERVK-21 ERVK-9 PGC ERVK-18 ERVK-24

5.38e-07381606GO:0070001
GeneOntologyMolecularFunctionendopeptidase activity

ATG4A MBTPS1 MMP28 PRSS55 ERVK-7 ERVK-21 ERVK-9 OVCH1 PGC MMP25 PHEX ERVK-18 MMP1 ERVK-24

9.88e-0643016014GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

ATG4A MBTPS1 UFSP2 MMP28 VASH1 PRSS55 ERVK-7 ERVK-21 DPP3 ERVK-9 OVCH1 PGC MMP25 PHEX ERVK-18 MMP1 ERVK-24

2.06e-0565416017GO:0008233
GeneOntologyMolecularFunctionnatural killer cell lectin-like receptor binding

HLA-E HLA-F CLEC2D

3.16e-04171603GO:0046703
GeneOntologyCellularComponentMHC protein complex

HLA-DOB HLA-DPB1 HLA-E HLA-F

4.44e-05261614GO:0042611
GeneOntologyCellularComponentextracellular matrix

FRAS1 MXRA5 CD248 MMP28 LAMB1 NYX TECTA MMP25 SNED1 MFAP5 PRELP KAZALD1 MMP1 NPNT HDGF

1.73e-0465616115GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

FRAS1 MXRA5 CD248 MMP28 LAMB1 NYX TECTA MMP25 SNED1 MFAP5 PRELP KAZALD1 MMP1 NPNT HDGF

1.79e-0465816115GO:0030312
MousePhenoabnormal immune serum protein physiology

SMG1 MBTPS1 APOBEC3D MMP28 ARHGEF5 HLA-E HLA-F PELI2 ARHGAP17 DPP3 PGAM5 BTN2A1 ARID5A MMP25 PHEX TNFRSF13B PKN1 IL1RL1 SLFN11 UNC93B1 PRKDC MMP1 SLC6A14 CD276

1.84e-05116511424MP:0002723
DomainEGF

TPO FRAS1 CD248 LAMB1 TECTA SNED1 NELL2 FAT2 TENM1 LRP2 NPNT

4.37e-0623515511SM00181
DomainIGc1

HLA-DOB HLA-DPB1 HLA-E HLA-F IGHA2 CD276

6.84e-06561556SM00407
DomainEGF-like_dom

TPO FRAS1 CD248 LAMB1 TECTA SNED1 NELL2 FAT2 TENM1 LRP2 NPNT

7.58e-0624915511IPR000742
DomainIg_C1-set

HLA-DOB HLA-DPB1 HLA-E HLA-F IGHA2 CD276

8.41e-06581556IPR003597
DomainCalx_beta

FRAS1 ADGRV1 SLC8A2

3.05e-0581553SM00237
DomainCalx_beta

FRAS1 ADGRV1 SLC8A2

4.54e-0591553IPR003644
DomainCalx-beta

FRAS1 ADGRV1 SLC8A2

4.54e-0591553PF03160
DomainGrowth_fac_rcpt_

FRAS1 CD248 LAMB1 NELL2 EGFR LRP2 KAZALD1 NPNT

4.82e-051561558IPR009030
DomainIG_LIKE

MXRA5 MYLK HLA-DOB HLA-DPB1 HLA-E HLA-F BTN2A1 IGHA2 CD101 KAZALD1 IL1RL1 MPZL2 IGSF3 CD276

6.15e-0549115514PS50835
DomainEGF_CA

TPO CD248 SNED1 NELL2 FAT2 LRP2 NPNT

7.14e-051221557SM00179
DomainEGF-like_Ca-bd_dom

TPO CD248 SNED1 NELL2 FAT2 LRP2 NPNT

7.91e-051241557IPR001881
DomainIg-like_dom

MXRA5 MYLK HLA-DOB HLA-DPB1 HLA-E HLA-F BTN2A1 IGHA2 CD101 KAZALD1 IL1RL1 MPZL2 IGSF3 CD276

7.95e-0550315514IPR007110
DomainC1-set

HLA-DOB HLA-DPB1 HLA-E HLA-F IGHA2

8.41e-05541555PF07654
DomainIg/MHC_CS

HLA-DOB HLA-DPB1 HLA-E HLA-F IGHA2

1.19e-04581555IPR003006
DomainIG_MHC

HLA-DOB HLA-DPB1 HLA-E HLA-F IGHA2

1.40e-04601555PS00290
DomainEGF_Ca-bd_CS

TPO CD248 SNED1 NELL2 LRP2 NPNT

1.57e-04971556IPR018097
DomainEGF_CA

TPO CD248 SNED1 NELL2 LRP2 NPNT

1.76e-04991556PS01187
DomainDUF2075

SLFN5 SLFN11

2.04e-0431552PF09848
DomainDUF2075

SLFN5 SLFN11

2.04e-0431552IPR018647
DomainEGF-type_Asp/Asn_hydroxyl_site

TPO CD248 SNED1 NELL2 LRP2 NPNT

2.55e-041061556IPR000152
DomainMHC_I/II-like_Ag-recog

HLA-DOB HLA-DPB1 HLA-E HLA-F

2.70e-04381554IPR011162
DomainEGF_1

TPO CD248 LAMB1 SNED1 NELL2 FAT2 TENM1 LRP2 NPNT

2.85e-042551559PS00022
DomainEGF-like_CS

TPO CD248 LAMB1 SNED1 NELL2 FAT2 TENM1 LRP2 NPNT

3.38e-042611559IPR013032
DomainEGF_2

TPO CD248 LAMB1 SNED1 NELL2 FAT2 TENM1 LRP2 NPNT

3.77e-042651559PS01186
DomainIGv

BTN2A1 CD101 MPZL2 IGSF3 CD276

3.99e-04751555SM00406
DomainPept_M10A_stromelysin-type

MMP28 MMP25 MMP1

4.17e-04181553IPR016293
DomainVWC_out

FRAS1 TECTA NELL2

4.93e-04191553SM00215
Domain6-blade_b-propeller_TolB-like

TENM1 LRP2 EIF3B LRP5L

5.68e-04461554IPR011042
DomainPG_binding_1

MMP28 MMP25 MMP1

5.76e-04201553PF01471
DomainPeptidoglycan-bd-like

MMP28 MMP25 MMP1

5.76e-04201553IPR002477
DomainNIDO_dom

TECTA SNED1

6.73e-0451552IPR003886
DomainNIDO

TECTA SNED1

6.73e-0451552SM00539
DomainNIDO

TECTA SNED1

6.73e-0451552PF06119
DomainNIDO

TECTA SNED1

6.73e-0451552PS51220
DomainFATC

SMG1 PRKDC

6.73e-0451552PF02260
DomainEGF_CA

TPO CD248 NELL2 LRP2 NPNT

7.48e-04861555PF07645
DomainEGF_3

TPO CD248 SNED1 NELL2 FAT2 TENM1 LRP2 NPNT

7.86e-042351558PS50026
DomainIg-like_fold

MXRA5 MYLK HLA-DOB HLA-DPB1 HLA-E HLA-F BTN2A1 SNED1 IGHA2 CD101 KAZALD1 IL1RL1 MPZL2 IGSF3 CD276

8.03e-0470615515IPR013783
DomainHemopexin-like_dom

MMP28 MMP25 MMP1

8.79e-04231553IPR000585
DomainHemopexin-like_repeat

MMP28 MMP25 MMP1

8.79e-04231553IPR018487
DomainHEMOPEXIN

MMP28 MMP25 MMP1

8.79e-04231553PS00024
Domain-

MMP28 MMP25 MMP1

8.79e-042315532.110.10.10
DomainHEMOPEXIN_2

MMP28 MMP25 MMP1

8.79e-04231553PS51642
DomainHX

MMP28 MMP25 MMP1

8.79e-04231553SM00120
DomainM10A_MMP

MMP28 MMP25 MMP1

8.79e-04231553IPR033739
DomainHemopexin

MMP28 MMP25 MMP1

8.79e-04231553PF00045
DomainPept_M10A

MMP28 MMP25 MMP1

8.79e-04231553IPR021190
DomainPeptidase_M10

MMP28 MMP25 MMP1

9.98e-04241553PF00413
DomainMHC_I_a_C

HLA-E HLA-F

1.00e-0361552IPR010579
DomainFAT

SMG1 PRKDC

1.00e-0361552PS51189
DomainFATC

SMG1 PRKDC

1.00e-0361552PS51190
DomainMHC_I_C

HLA-E HLA-F

1.00e-0361552PF06623
DomainFATC_dom

SMG1 PRKDC

1.00e-0361552IPR003152
DomainPIK_FAT

SMG1 PRKDC

1.00e-0361552IPR014009
DomainFATC

SMG1 PRKDC

1.00e-0361552SM01343
Domain-

MXRA5 MYLK HLA-DOB HLA-DPB1 HLA-E HLA-F BTN2A1 SNED1 CD101 KAZALD1 IL1RL1 MPZL2 IGSF3 CD276

1.27e-03663155142.60.40.10
DomainAlbA_2

SLFN5 SLFN11

1.40e-0371552PF04326
DomainSchlafen

SLFN5 SLFN11

1.40e-0371552IPR029684
DomainSchlafen_AAA_dom

SLFN5 SLFN11

1.40e-0371552IPR007421
DomainRetrov_capsid_C

ZNF274 ZNF213 ZSCAN32 ERVK-5

1.46e-03591554IPR008916
DomainASX_HYDROXYL

TPO SNED1 NELL2 LRP2 NPNT

1.47e-031001555PS00010
DomainPeptidase_Metallo

MMP28 MMP25 MMP1

1.75e-03291553IPR006026
DomainZnMc

MMP28 MMP25 MMP1

1.75e-03291553SM00235
DomainMHC_II_b_N

HLA-DOB HLA-DPB1

1.85e-0381552PD000328
DomainMHC_II_b_N

HLA-DOB HLA-DPB1

2.37e-0391552IPR000353
DomainMHC_II_beta

HLA-DOB HLA-DPB1

2.37e-0391552SM00921
DomainMHC_II_beta

HLA-DOB HLA-DPB1

2.37e-0391552PF00969
DomainConA-like_dom

ADGRV1 BTN2A1 NELL2 FAT2 HNRNPUL2 NPNT TRIM60

2.38e-032191557IPR013320
Domain-

ARHGEF19 PLEKHG4 ARHGEF5 ALS2CL

2.88e-037115541.20.900.10
DomainDH-domain

ARHGEF19 PLEKHG4 ARHGEF5 ALS2CL

2.88e-03711554IPR000219
DomainVWFC_2

FRAS1 TECTA NELL2

3.82e-03381553PS50184
DomainVWC

FRAS1 TECTA NELL2

3.82e-03381553SM00214
DomainEGF

CD248 TECTA SNED1 FAT2 LRP2

4.03e-031261555PF00008
Domain-

TENM1 LRP2 LRP5L

4.12e-033915532.120.10.30
Domain-

MMP28 MMP25 PHEX MMP1

4.63e-038115543.40.390.10
DomainMetalloPept_cat_dom

MMP28 MMP25 PHEX MMP1

4.63e-03811554IPR024079
DomainCYSTEINE_SWITCH

MMP28 MMP25 MMP1

4.74e-03411553PS00546
DomainABC_transporter_CS

ABCC3 ABCA1 ABCB8

5.08e-03421553IPR017871
DomainVWF_dom

FRAS1 TECTA NELL2

5.08e-03421553IPR001007
DomainPept_M10_metallopeptidase

MMP28 MMP25 MMP1

5.43e-03431553IPR001818
DomainMHC_II_a/b_N

HLA-DOB HLA-DPB1

5.83e-03141552IPR014745
DomainTIL_dom

TECTA LRP2

5.83e-03141552IPR002919
Domain-

HLA-DOB HLA-DPB1

5.83e-031415523.10.320.10
DomainLdl_recept_b

LRP2 LRP5L

5.83e-03141552PF00058
DomainLDLRB

LRP2 LRP5L

5.83e-03141552PS51120
DomainPI3/4_kinase_CS

SMG1 PRKDC

6.69e-03151552IPR018936
DomainLY

LRP2 LRP5L

6.69e-03151552SM00135
DomainLDLR_classB_rpt

LRP2 LRP5L

6.69e-03151552IPR000033
DomainAAA

ABCC3 ABCA1 ATAD5 CLPB ABCB8

7.05e-031441555SM00382
DomainAAA+_ATPase

ABCC3 ABCA1 ATAD5 CLPB ABCB8

7.05e-031441555IPR003593
DomainABC_tran

ABCC3 ABCA1 ABCB8

7.38e-03481553PF00005
DomainABC_TRANSPORTER_2

ABCC3 ABCA1 ABCB8

7.38e-03481553PS50893
Domain-

SMG1 PRKDC

7.61e-031615521.10.1070.11
DomainPI3Kc

SMG1 PRKDC

7.61e-03161552SM00146
DomainABC_TRANSPORTER_1

ABCC3 ABCA1 ABCB8

7.81e-03491553PS00211
DomainABC_transporter-like

ABCC3 ABCA1 ABCB8

8.26e-03501553IPR003439
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ABCC3 CACNA2D1 MBTPS1 FRAS1 HLA-E HLA-F LPCAT4 LAMB1 DDX55 BTN2A1 NELL2 DNAJC10 EGFR HNRNPUL2 DHCR7 TNKS1BP1 TIMELESS UNC93B1 PCDH7 MFSD5 MSLN IGSF3 CD276

9.92e-0912011622335696571
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-7 ERVK-21 ERVK-18

9.85e-075162312629516
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-18 ERVK-24

1.32e-0618162418664271
Pubmed

HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells.

HLA-DOB HLA-DPB1 HLA-E HLA-F

2.07e-0620162412427289
Pubmed

Nef performance in macrophages: the master orchestrator of viral persistence and spread.

HLA-DOB HLA-DPB1 HLA-E HLA-F

2.07e-0620162422103834
Pubmed

HIV-1 gp41 binding proteins and antibodies to gp41 could inhibit enhancement of human Raji cell MHC class I and II expression by gp41.

HLA-DOB HLA-DPB1 HLA-E HLA-F

2.55e-062116248084338
Pubmed

Strategies for inhibiting function of HIV-1 accessory proteins: a necessary route to AIDS therapy?

HLA-DOB HLA-DPB1 HLA-E HLA-F RNF216

2.70e-0647162519149577
Pubmed

Role of HIV-1 Nef protein for virus replication in vitro.

HLA-DOB HLA-DPB1 HLA-E HLA-F

3.75e-0623162419770068
Pubmed

Editorial. Nef: a notorious enigmatic factor in HIV biology.

HLA-DOB HLA-DPB1 HLA-E HLA-F

4.48e-0624162422175768
Pubmed

HIV accessory proteins and surviving the host cell.

HLA-DOB HLA-DPB1 HLA-E HLA-F

5.32e-0625162416091223
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-7 ERVK-21 ERVK-9 ERVK-18 ERVK-5 ERVK-24

5.40e-0694162621542922
Pubmed

A nonclassical MHC class I molecule restricts CTL-mediated rejection of a syngeneic melanoma tumor.

HLA-E HLA-F PRKDC

5.46e-068162315383569
Pubmed

[The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway].

HLA-DOB HLA-DPB1 HLA-E HLA-F

7.32e-0627162412836198
Pubmed

Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob.

HLA-DOB HLA-E HLA-F

8.16e-069162328813660
Pubmed

Polymorphism of the Apl (Neu-1) locus in the mouse.

HLA-E HLA-F PGC

8.16e-06916237141491
Pubmed

One protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef.

HLA-DOB HLA-DPB1 HLA-E HLA-F

8.51e-0628162422103833
Pubmed

HIV/SIV escape from immune surveillance: focus on Nef.

HLA-DOB HLA-DPB1 HLA-E HLA-F

9.84e-0629162415078178
Pubmed

Acute Myeloid Leukemia Causes T Cell Exhaustion and Depletion in a Humanized Graft-versus-Leukemia Model.

HLA-E HLA-F PRKDC

1.16e-0510162337712758
Pubmed

HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice.

HLA-E HLA-F PRKDC

1.16e-0510162337877672
Pubmed

Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγ(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells.

HLA-E HLA-F PRKDC

1.16e-0510162323869841
Pubmed

Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti-PD-1 Immune Checkpoint Inhibitor Cancer Therapy.

HLA-E HLA-F PRKDC

1.16e-0510162338426910
Pubmed

Gene organization and recombinational hotspots in the murine major histocompatibility complex.

HLA-DOB HLA-E HLA-F

1.16e-051016233754180
Pubmed

NLGN4X TCR transgenic T cells to treat gliomas.

HLA-E HLA-F PRKDC

1.16e-0510162337715782
Pubmed

Genetic and molecular mapping of the Hmt region of mouse.

HLA-E HLA-F PGC

1.16e-051016232573520
Pubmed

Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model.

HLA-E HLA-F PRKDC

1.16e-0510162337219526
Pubmed

Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer.

HLA-E HLA-F PRKDC

1.16e-0510162337966111
Pubmed

Immunoregulatory effects of HIV-1 Nef protein.

HLA-DOB HLA-DPB1 HLA-E HLA-F

1.47e-0532162419449444
Pubmed

Differential effect of ATP binding cassette transporter A1 R219K and cholesteryl ester transfer protein TaqIB genotypes on HDL-C levels in overweight/obese and non-obese Chinese subjects.

ABCA1 CETP

2.16e-052162221591583
Pubmed

HLA-E and HLA-F Are Overexpressed in Glioblastoma and HLA-E Increased After Exposure to Ionizing Radiation.

HLA-E HLA-F

2.16e-052162235181585
Pubmed

HLA-F complex without peptide binds to MHC class I protein in the open conformer form.

HLA-E HLA-F

2.16e-052162220483783
Pubmed

Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase.

EGFR PRKDC

2.16e-052162216000298
Pubmed

Activated platelets rescue apoptotic cells via paracrine activation of EGFR and DNA-dependent protein kinase.

EGFR PRKDC

2.16e-052162225210793
Pubmed

Associations of genetic variants in ATP-binding cassette A1 and cholesteryl ester transfer protein and differences in lipoprotein subclasses in the multi-ethnic study of atherosclerosis.

ABCA1 CETP

2.16e-052162219131637
Pubmed

EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment.

EGFR PRKDC

2.16e-052162221266349
Pubmed

A novel variant of human Grb7 is associated with invasive esophageal carcinoma.

GRB7 EGFR

2.16e-05216229710451
Pubmed

Aldehyde dehydrogenase 1/epidermal growth factor receptor coexpression is characteristic of a highly aggressive, poor-prognosis subgroup of high-grade serous ovarian carcinoma.

EGFR ALDH1A1

2.16e-052162223465277
Pubmed

Phosphate transport in osteoblasts from normal and X-linked hypophosphatemic mice.

LAMB1 PHEX

2.16e-05216228082056
Pubmed

Cholesteryl ester transfer protein and ATP-binding cassette transporter A1 genotype alter the atorvastatin and simvastatin efficacy: time for genotype-guided therapy?

ABCA1 CETP

2.16e-052162222584245
Pubmed

ERK/MAPK pathways play critical roles in EGFR ligands-induced MMP1 expression.

EGFR MMP1

2.16e-052162221440529
Pubmed

The impact of common polymorphisms in CETP and ABCA1 genes with the risk of coronary artery disease in Saudi Arabians.

ABCA1 CETP

2.16e-052162226936456
Pubmed

Human leukocyte antigen (HLA)-E and HLA-F expression in gastric cancer.

HLA-E HLA-F

2.16e-052162225862890
Pubmed

SP3-induced Timeless transcription contributes to cell growth of lung adenocarcinoma cells.

SP3 TIMELESS

2.16e-052162238354174
Pubmed

Mapping of the L-methylmalonyl-CoA mutase gene to mouse chromosome 17.

HLA-E HLA-F PGC

2.74e-051316231970332
Pubmed

The I region of the C57BL/10 mouse: characterization and physical linkage to H-2K of an SB beta-like class II pseudogene, psi A beta 3.

HLA-DOB HLA-E HLA-F

3.48e-051416233860873
Pubmed

Electrophoretic analysis of liver neuraminidase-1 variation in mice and additional evidence concerning the location of NEU-1.

HLA-E HLA-F PGC

3.48e-051416233745925
Pubmed

Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors.

HLA-E HLA-F CLEC2D

4.33e-0515162314990792
Pubmed

Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity.

HLA-E HLA-F PRKDC

4.33e-0515162338413714
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMG1 RAN MYLK BIVM LPCAT4 DDX55 PGAM5 PHEX DNAJC10 SACS N4BP2 SLC27A1 TENM1 CES3 DLAT PRKDC ALDH1A1 POTEI SLC6A14

4.55e-0514421621935575683
Pubmed

Maternal and fetal variation in genes of cholesterol metabolism is associated with preterm delivery.

ABCA1 CETP DHCR7

5.31e-0516162317855807
Pubmed

Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING.

HLA-E HLA-F PRKDC

5.31e-0516162332723479
Pubmed

Localization of a mouse heat shock Hsp70 gene within the H-2 complex.

HLA-DOB HLA-E HLA-F

6.43e-051716231978715
Pubmed

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

KIF21B HLA-E LAMB1

6.43e-0517162319915572
Pubmed

The majority of H2-M3 is retained intracellularly in a peptide-receptive state and traffics to the cell surface in the presence of N-formylated peptides.

HLA-E HLA-F

6.45e-053162210430630
Pubmed

[Single nucleotide polymorphisms of genes associated with high density lipoprotein metabolism in Chinese population].

ABCA1 CETP

6.45e-053162215696473
Pubmed

Characterization of a new subfamily of class I genes in the H-2 complex of the mouse.

HLA-E HLA-F

6.45e-05316223378834
Pubmed

Threonine 2609 phosphorylation of the DNA-dependent protein kinase is a critical prerequisite for epidermal growth factor receptor-mediated radiation resistance.

EGFR PRKDC

6.45e-053162222923485
Pubmed

Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells.

HLA-E HLA-F

6.45e-053162228740236
Pubmed

Comparative genomic aspects of rat, mouse and human MHC class I gene regions.

HLA-E HLA-F

6.45e-053162211173841
Pubmed

Removal of Qa-2 antigen alters the Ped gene phenotype of preimplantation mouse embryos.

HLA-E HLA-F

6.45e-05316221327207
Pubmed

Fine map of a region homologous to the rat grc complex in the TL region of the mouse.

HLA-E HLA-F

6.45e-05316228428772
Pubmed

Is dyslipidemia sustained during remission of nephrotic syndrome genetically determined? Evaluation of genetic polymorphisms of proteins involved in lipoprotein metabolism in children and adolescents with nephrotic syndrome.

ABCA1 CETP

6.45e-053162219341173
Pubmed

Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK.

EGFR PRKDC

6.45e-053162218789131
Pubmed

CTL and sequence analyses of MHC class IB antigens Qa1(c) (H2-T23(r)) and Qa1(d) (H2-T23(f)).

HLA-E HLA-F

6.45e-053162210369933
Pubmed

Antigen-presenting cells for naive transgenic gamma delta T cells. Potent activation by activated alpha beta T cells.

HLA-E HLA-F

6.45e-05316227561093
Pubmed

Critical role of Qa1b in the protection of mature dendritic cells from NK cell-mediated killing.

HLA-E HLA-F

6.45e-053162218028286
Pubmed

Molecular cloning of a second human stanniocalcin homologue (STC2).

CRY2 PHEX

6.45e-05316229753616
Pubmed

Organization and structure of the H-2M4-M8 class I genes in the mouse major histocompatibility complex.

HLA-E HLA-F

6.45e-05316228319975
Pubmed

Expression of nonclassical class I major histocompatibility genes defines a tripartite organization of the mouse vomeronasal system.

HLA-E HLA-F

6.45e-053162218322080
Pubmed

Analysis of litter size and weight in mice differing in Ped gene phenotype and the Q region of the H-2 complex.

HLA-E HLA-F

6.45e-05316221865393
Pubmed

Hyperconservation of the N-formyl peptide binding site of M3: evidence that M3 is an old eutherian molecule with conserved recognition of a pathogen-associated molecular pattern.

HLA-E HLA-F

6.45e-053162212847252
Pubmed

Linkage of the preimplantation-embryo-development (Ped) gene to the mouse major histocompatibility complex (MHC).

HLA-E HLA-F

6.45e-05316223593832
Pubmed

Duplicated gene pairs and alleles of class I genes in the Qa2 region of the murine major histocompatibility complex: a comparison.

HLA-E HLA-F

6.45e-05316223004940
Pubmed

Murine MHC class Ib gene, H2-M2, encodes a conserved surface-expressed glycoprotein.

HLA-E HLA-F

6.45e-053162215045471
Pubmed

HMT, encoded by H-2M3, is a neoclassical major histocompatibility class I antigen.

HLA-E HLA-F

6.45e-05316228464890
Pubmed

A cDNA clone encoding the mouse Qa-1a histocompatibility antigen and proposed structure of the putative peptide binding site.

HLA-E HLA-F

6.45e-05316228245452
Pubmed

ADAP2 in heart development: a candidate gene for the occurrence of cardiovascular malformations in NF1 microdeletion syndrome.

SUZ12 ADAP2

6.45e-053162224711647
Pubmed

Increased risk of premature coronary artery disease in Egyptians with ABCA1 (R219K), CETP (TaqIB), and LCAT (4886C/T) genes polymorphism.

ABCA1 CETP

6.45e-053162225110219
Pubmed

Phosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period length.

CRY2 PRKDC

6.45e-053162224158435
Pubmed

Identification of two major histocompatibility complex class Ib genes, Q7 and Q9, as the Ped gene in the mouse.

HLA-E HLA-F

6.45e-053162210208972
Pubmed

BLyF, a novel cell-type- and stage-specific regulator of the B-lymphocyte gene mb-1.

HLA-E HLA-F

6.45e-05316221545794
Pubmed

Extension of the H-2 TLb molecular map. Isolation and characterization of T13, T14, and T15 from the C57BL/6 mouse.

HLA-E HLA-F

6.45e-05316222831142
Pubmed

Two "Qa" specificities: Qa-m7 and Qa-m8 defined by monoclonal antibodies.

HLA-E HLA-F

6.45e-05316226190932
Pubmed

Analysis of the Qa-4 allodeterminant.

HLA-E HLA-F

6.45e-05316222581893
Pubmed

Class Ib MHC-Mediated Immune Interactions Play a Critical Role in Maintaining Mucosal Homeostasis in the Mammalian Large Intestine.

HLA-E HLA-F

6.45e-053162234911745
Pubmed

Nuclear EGFR suppresses ribonuclease activity of polynucleotide phosphorylase through DNAPK-mediated phosphorylation at serine 776.

EGFR PRKDC

6.45e-053162222815474
Pubmed

[Geographical characteristics of single nucleotide polymorphism of candidate genes associated with coronary artery disease in Chinese Han population].

ABCA1 CETP

6.45e-053162219099922
Pubmed

Repression of the nonclassical MHC class I gene H2-M1 by cis-acting silencer DNA elements.

HLA-E HLA-F

6.45e-05316228753857
Pubmed

Combinatorial coexpression of neural and immune multigene families in mouse vomeronasal sensory neurons.

HLA-E HLA-F

6.45e-053162212620187
Pubmed

Expression in L cells of transfected class I genes from the mouse major histocompatibility complex.

HLA-E HLA-F

6.45e-05316222991930
Pubmed

Polymorphism within a TCRAV family influences the repertoire through class I/II restriction.

HLA-E HLA-F

6.45e-05316229570535
Pubmed

Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues.

HLA-E HLA-F

6.45e-053162233020145
Pubmed

Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer's disease.

ABCA1 CETP

6.45e-053162223181436
Pubmed

Regulation of human CETP gene expression: role of SP1 and SP3 transcription factors at promoter sites -690, -629, and -37.

SP3 CETP

6.45e-053162212730302
Pubmed

Identification of the Ped gene at the molecular level: the Q9 MHC class I transgene converts the Ped slow to the Ped fast phenotype.

HLA-E HLA-F

6.45e-05316227819451
Pubmed

Novel mRNA species from a Q-subregion class-I gene of the murine major histocompatibility complex.

HLA-E HLA-F

6.45e-05316223443307
Pubmed

Reduced alpha-adrenoceptor responsiveness and enhanced baroreflex sensitivity in Cry-deficient mice lacking a biological clock.

CRY2 CNN1

6.45e-053162215860530
Pubmed

Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection.

HLA-E HLA-F

6.45e-053162230970256
Pubmed

Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition.

HLA-E HLA-F

6.45e-053162212874228
Pubmed

HLA-E, HLA-F, and HLA-G polymorphism: genomic sequence defines haplotype structure and variation spanning the nonclassical class I genes.

HLA-E HLA-F

6.45e-053162216570139
Pubmed

Role of the Ped gene and apoptosis genes in control of preimplantation development.

HLA-E HLA-F

6.45e-05316229604770
InteractionFBXO2 interactions

CACNA2D1 FRAS1 LAMB1 ADGRV1 BTN2A1 CBLIF SNED1 NELL2 PPT2 EGFR PRELP CD101 LRP2 IGSF3 CD276

6.34e-0741115415int:FBXO2
Cytoband6p22.3-p22.1

MRS2 SCGN

7.39e-05416226p22.3-p22.1
CytobandEnsembl 112 genes in cytogenetic band chr17q12

MMP28 MRM1 GRB7 SLFN5 SLFN11

1.95e-041491625chr17q12
Cytoband17q12

MRM1 GRB7 SLFN5 SLFN11

4.33e-0499162417q12
GeneFamilyC1-set domain containing

HLA-DOB HLA-DPB1 HLA-E HLA-F

9.77e-05421044591
GeneFamilyHistocompatibility complex|C1-set domain containing

HLA-DOB HLA-DPB1 HLA-E HLA-F

1.18e-04441044588
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP28 MMP25 MMP1

3.43e-04241043891
GeneFamilySchlafen family

SLFN5 SLFN11

6.75e-04710421110
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MXRA5 MYLK CD101 KAZALD1 IL1RL1

2.38e-031611045593
GeneFamilyAdenosine receptors|V-set domain containing

BTN2A1 CD101 MPZL2 IGSF3 CD276

2.51e-031631045590
CoexpressionNABA_CORE_MATRISOME

FRAS1 MXRA5 LAMB1 NYX TECTA SNED1 MFAP5 NELL2 PRELP VWA5B1 NPNT

8.43e-0727515611M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

FRAS1 MXRA5 LAMB1 TECTA SNED1 MFAP5 NELL2 VWA5B1 NPNT

2.82e-061961569M3008
CoexpressionNABA_CORE_MATRISOME

FRAS1 LAMB1 NYX TECTA SNED1 MFAP5 NELL2 PRELP VWA5B1 NPNT

5.34e-0627015610MM17057
CoexpressionDESCARTES_ORGANOGENESIS_WHITE_BLOOD_CELLS

ABCC3 APOBEC3D HLA-E HLA-F ARHGAP17 NRROS SP110 ARID5A CLEC2D PKN1 IL1RL1 SLFN11 UNC93B1 ADAP2

1.98e-0561515614MM3641
CoexpressionNABA_ECM_GLYCOPROTEINS

FRAS1 LAMB1 TECTA SNED1 MFAP5 NELL2 VWA5B1 NPNT

1.98e-051911568MM17059
CoexpressionLEE_BMP2_TARGETS_UP

ABCA1 APOBEC3D HLA-E HLA-F GRB7 PELI2 CRY2 ACAD8 SCMH1 PRELP DCHS1 PKN1 UNC93B1 MPZL2 IGSF3 NPNT

2.62e-0580515616MM1067
CoexpressionNABA_MATRISOME

TPO FRAS1 MXRA5 MMP28 WNT8B LAMB1 NYX TECTA MMP25 SNED1 MFAP5 NELL2 PRELP CLEC2D KAZALD1 MMP1 VWA5B1 NPNT

4.17e-05102615618M5889
CoexpressionLIU_PROSTATE_CANCER_DN

ABCC3 MYLK CD248 HLA-E LPCAT4 LAMB1 SLFN5 BTN2A1 NELL2 PRELP MPZL2 PCDH7

4.18e-0549315612M19391
CoexpressionYU_MYC_TARGETS_DN

ABCA1 HLA-DOB HLA-E HLA-F UNC93B1

5.40e-05681565MM632
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_1000

FRAS1 PDE3A ABCA1 MYLK CYP2E1 CD248 HLA-F SLFN5 SP110 MFAP5 EGFR PRELP CLEC2D CES3 LRP2 KAZALD1 ALDH1A1 MPZL2 MSLN NPNT

1.04e-0677815520gudmap_kidney_adult_RenalCapsule_1000
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAN HLA-DOB HLA-DPB1 INPP5F SNED1 SACS IGHA2 CLEC2D TNFRSF13B EIF3B

1.97e-09196156100175b097ad1338a07afebe3b5c7fd0bb0bb950f7
ToppCellfacs-BAT-Fat-18m-Mesenchymal|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 CD248 LAMB1 MFAP5 EGFR PRELP ALDH1A1 PCDH7 IGSF3

2.36e-081891569bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 CD248 LAMB1 MFAP5 EGFR PRELP ALDH1A1 PCDH7 IGSF3

2.36e-081891569cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 CD248 LAMB1 MFAP5 EGFR PRELP ALDH1A1 PCDH7 IGSF3

2.36e-08189156987323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAN HLA-DOB HLA-DPB1 INPP5F SACS IGHA2 CLEC2D TNFRSF13B EIF3B

3.09e-081951569a4d36654b968acb1aea252ac203683939461f1d1
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAN HLA-DOB HLA-DPB1 INPP5F SACS IGHA2 CLEC2D TNFRSF13B EIF3B

3.09e-081951569cd811abd949ef201aef1c8515da5575ab1b1cfea
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAN HLA-DOB HLA-DPB1 INPP5F SACS IGHA2 CLEC2D TNFRSF13B EIF3B

3.23e-081961569fd756b247b2d8a291e8e71bec6f1e463d6557536
ToppCellPBMC-Mild-cDC_3|Mild / Compartment, Disease Groups and Clusters

HLA-DOB HLA-DPB1 GRB7 FAM170B IL1RL1 PCDH7 ZNF548 CNN1

9.04e-0815815685fefab4831687cd8dd45f5cc84f681398069c3be
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MXRA5 LAMB1 ARL4D FAT2 EGFR ALDH1A1 MPZL2 PCDH7

3.03e-071851568e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA2D1 MYLK LAMB1 PHEX SNED1 MFAP5 ALDH1A1 NPNT

4.02e-07192156825492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA2D1 MYLK LAMB1 PHEX SNED1 MFAP5 ALDH1A1 NPNT

4.02e-071921568de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA2D1 MYLK LAMB1 PHEX SNED1 MFAP5 ALDH1A1 NPNT

4.52e-0719515683a0cad69cfc150a27a0666f612f5294c817197d7
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA2D1 MYLK LAMB1 PHEX SNED1 MFAP5 ALDH1A1 NPNT

4.52e-0719515682b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 MXRA5 MYLK LAMB1 ARL4D PHEX PRELP NPNT

5.47e-0720015688c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCellBasal_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 EPPK1 ARL4D CNNM1 FAT2 ASXL3 PCDH7

2.01e-061661567aea2ae12e4746149ebc6da063ef694381c098f80
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 NUP210L LAMB1 MFAP5 EGFR PRELP IGSF3

2.97e-061761567fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 NUP210L LAMB1 MFAP5 EGFR PRELP IGSF3

2.97e-061761567f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK CD248 ARHGEF5 FAM170B ZMYND10 PRELP ADAP2

3.20e-0617815677467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PDE3A NUP210L MMP28 EXTL1 SLC22A13 KAZALD1 ALDH1A1

3.32e-0617915678c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 MYLK LAMB1 PRELP UBAP1L ALDH1A1 NPNT

3.70e-061821567c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 MYLK LAMB1 PRELP UBAP1L ALDH1A1 NPNT

3.70e-061821567dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DOB HLA-DPB1 ARL4D MFAP5 IGHA2 CLEC2D TNFRSF13B

4.27e-061861567d7d884ff4184636081c350d29f797bd923c6a3b4
ToppCellnormal-na-Lymphocytic_B-B_atypical-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DOB HLA-DPB1 NRROS ARL4D MFAP5 CLEC2D TNFRSF13B

4.58e-061881567e5ab89030783461e9367ab87c353fb5c31911020
ToppCellnormal-na-Lymphocytic_B-B_atypical|normal / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DOB HLA-DPB1 NRROS ARL4D MFAP5 CLEC2D TNFRSF13B

4.58e-06188156713653481d64c7a1ad833d738a3ee0bb9def7cec7
ToppCellCTRL-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

CLIP2 HLA-DOB HLA-DPB1 INPP5F SP110 SNED1 TNFRSF13B

4.74e-06189156714f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA2D1 MYLK LAMB1 MFAP5 PRELP ALDH1A1 NPNT

4.74e-061891567e76dc36a01d8ad7590b3acc4c46abfcb76857448
ToppCellremission-B_memory|World / disease stage, cell group and cell class

HLA-DOB HLA-DPB1 FAM110D SP110 MFAP5 IGHA2 TNFRSF13B

4.91e-061901567c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCelldroplet-Lung-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA2D1 MYLK LAMB1 MFAP5 PRELP ALDH1A1 NPNT

4.91e-0619015670b7200897b2c389632c9b1ee37e272b811555dbc
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA2D1 MYLK LAMB1 MFAP5 PRELP ALDH1A1 NPNT

5.08e-061911567c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA2D1 MYLK LAMB1 MFAP5 PRELP ALDH1A1 NPNT

5.08e-061911567243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCelldroplet-Lung-30m-Mesenchymal|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA2D1 MYLK LAMB1 MFAP5 PRELP ALDH1A1 NPNT

5.26e-0619215675d5bec238b196f0b3e727fd94f078d6ae524cb01
ToppCelldroplet-Lung-nan-18m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 MYLK LAMB1 MFAP5 PRELP ALDH1A1 NPNT

5.26e-061921567df56c3e3bb1aafc1126607f4426554c09c8c40cf
ToppCellfacs-BAT-Fat-24m-Mesenchymal-mesenchymal_progenitor|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 LAMB1 MFAP5 EGFR PRELP KAZALD1 IGSF3

5.26e-0619215670b3161ce3add9f7457f4cfa5749dbb6501e3ad36
ToppCellfacs-BAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 LAMB1 MFAP5 EGFR PRELP KAZALD1 IGSF3

5.26e-06192156761c7ec6171c519b2f3e9ce623669162c0c6ba9f5
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A MYLK LAMB1 PHEX SNED1 ALDH1A1 PCDH7

5.26e-061921567162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellfacs-BAT-Fat-24m-Mesenchymal|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 LAMB1 MFAP5 EGFR PRELP KAZALD1 IGSF3

5.26e-06192156724d682e3247a73d349e7776b9e564b6b57f4cb13
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA2D1 LAMB1 MFAP5 PRELP ALDH1A1 IGSF3 NPNT

5.26e-0619215671b228f0929b505de82a39bf64c837887b0e56701
ToppCellNS-critical-d_0-4-Lymphoid-NK|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MXRA5 APOBEC3D CD248 BIVM PMVK IL1RL1 MMP1

5.44e-0619315671b29525c5936d1b779253b8c20f059fa091c6127
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA2D1 MYLK LAMB1 MFAP5 PRELP ALDH1A1 NPNT

5.44e-0619315674c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK LAMB1 PHEX PRELP ALDH1A1 ADAP2 NPNT

5.44e-061931567027e098ad018e782287f84eee0f77551018f2196
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA2D1 MYLK LAMB1 MFAP5 PRELP ALDH1A1 NPNT

5.44e-061931567ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCellPND28-Mesenchymal-Mesenchymal_structural|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD248 LAMB1 SNED1 MFAP5 PRELP MSLN NPNT

5.44e-061931567ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK LAMB1 PHEX PRELP ALDH1A1 ADAP2 NPNT

5.44e-061931567c5463a87f20b3a7f7ffda677b2f5a0e9e49d6685
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK LAMB1 MFAP5 PRELP ALDH1A1 ADAP2 NPNT

5.44e-061931567abdfb8b1dbdcb424042e21017a9e829fced4457e
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CACNA2D1 FRAS1 MYLK LAMB1 PHEX SNED1 PCDH7

5.44e-061931567acad568621ed677031797b8c2e34dafea798d681
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD248 LAMB1 SNED1 MFAP5 PRELP MSLN NPNT

5.44e-06193156730481fb01c7acf85beae10213f038da86bed6777
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A MYLK LAMB1 PHEX SNED1 ASXL3 PCDH7

5.63e-06194156789b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGEF5 GRB7 ARL4D FAT2 ALDH1A1 MPZL2 MSLN

5.82e-06195156724d226f89dd337c22728688e4b40ca082a0e1fe1
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYLK LAMB1 ARL4D MFAP5 PCDH7 CNN1 NPNT

5.82e-0619515676524ee7bdc70bb5955dd6a6f134a8e6d8b5f2b39
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 CD248 LAMB1 SNED1 MFAP5 EGFR PRELP

6.02e-061961567787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PDE3A MXRA5 MYLK CD248 LAMB1 PRELP TNKS1BP1

6.02e-06196156744e2df1b61e3819eae7e482bef0a733afe852d67
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PDE3A MXRA5 MYLK CD248 LAMB1 PRELP TNKS1BP1

6.02e-061961567cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 CD248 LAMB1 SNED1 MFAP5 EGFR PRELP

6.02e-061961567b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-myocytic|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYLK LAMB1 ARL4D MFAP5 PCDH7 CNN1 NPNT

6.02e-06196156720dc9b25ecc23b6e6e52bbab8b5a404f3245ca37
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 MYLK LAMB1 PHEX PRELP ALDH1A1 NPNT

6.22e-061971567156155c2f0c1a2461e45803da578af18ee221660
ToppCellBasal_cells|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 MXRA5 ARL4D FAT2 EGFR MMP1 PCDH7

6.22e-06197156724360b660000bdfb999d58fbf4e29585a97e1785
ToppCellSevere_COVID-19-Epithelial-transitional_Epi|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

EPPK1 ALS2CL ZMYND10 IL1RL1 MPZL2 SLC6A14 MSLN

6.22e-0619715675ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EPPK1 ALS2CL ZMYND10 IL1RL1 MPZL2 SLC6A14 MSLN

6.22e-06197156708b371309cd790b171ed76cabc7d910e71cd2835
ToppCell368C-Fibroblasts-Fibroblast-G-|368C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 MYLK LAMB1 PHEX PRELP ALDH1A1 NPNT

6.22e-061971567d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCellPND14-Mesenchymal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYLK CD248 LAMB1 MFAP5 KAZALD1 CNN1 NPNT

6.22e-0619715679a14bc2e7d6081e2ab0e2e5555fc8804f13d3dbe
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

EPPK1 ALS2CL ZMYND10 IL1RL1 MPZL2 SLC6A14 MSLN

6.22e-0619715679f49feee38647bbf964974aac96fa75602186b5c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPPK1 EGFR MMP1 MPZL2 PCDH7 SLC6A14 HDGF

6.43e-06198156777517df37dc894c78ef1e2b24dd7ba31f928bdb7
ToppCellSevere-B_intermediate-10|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HLA-DPB1 HLA-E ARL4D PHEX MFAP5 CLEC2D ADAP2

6.43e-061981567dfae26c3513a82bb7cb8dadbfcea2a1f420b1bab
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC3 FRAS1 FAT2 EGFR ASXL3 PCDH7 IGSF3

6.65e-06199156794a7867e800df352731796de8c24cba133c29622
ToppCellSkin-Mesangial|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

PDE3A MYLK ATAD5 WNT8B TECTA ARID5A CNN1

6.65e-061991567bcb78838a91cc7828680fb413fbacdb091c5fac0
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FRAS1 MYLK LAMB1 PHEX PRELP ALDH1A1 NPNT

6.65e-061991567b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_activated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NBPF3 ABCC3 APOBEC3D HLA-DOB INPP5F ZNF589 ADAP2

6.65e-0619915673b2bd3caf4d189a1726a737b0121860b265eec04
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MXRA5 ARL4D FAT2 EGFR ALDH1A1 MPZL2 PCDH7

6.65e-061991567ba284f984909504221900bca5ea12ada5b2ffd9f
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 MYLK LAMB1 PHEX PRELP ALDH1A1 NPNT

6.65e-061991567212e89d097753790061310373a1fafba773488b6
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 MYLK LAMB1 PHEX PRELP ALDH1A1 NPNT

6.65e-06199156714b676aa289c0578a37be32cec3ea285c79d97cc
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

MYLK SLFN5 DNAJC10 MPZL2 PCDH7 CNN1 NPNT

6.65e-06199156718a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCellPSB-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCC3 MXRA5 LAMB1 ARL4D FAT2 EGFR MPZL2

6.65e-0619915672add64c3e4cb6384ec381f34c3f1f77e13e3f27c
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

FRAS1 MYLK LAMB1 PHEX PRELP PCDH7 NPNT

6.87e-062001567aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FRAS1 MYLK LAMB1 PHEX PRELP PCDH7 NPNT

6.87e-062001567a510deaada669e690329183e18df02870bd204b3
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MXRA5 CD248 LAMB1 ARL4D MFAP5 KAZALD1 PCDH7

6.87e-06200156776f3043cb88071256ff661885fe5a82a54f5b733
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FRAS1 MXRA5 CD248 LAMB1 EGFR NPNT CD276

6.87e-062001567ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MXRA5 CD248 LAMB1 ARL4D MFAP5 KAZALD1 PCDH7

6.87e-06200156764d2941689d7ca8af54f9ba21c5aeabf719084ef
ToppCellBiopsy_Other_PF-Mesenchymal|Biopsy_Other_PF / Sample group, Lineage and Cell type

PDE3A MXRA5 MYLK CD248 LAMB1 PRELP CNN1

6.87e-062001567d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FRAS1 MYLK LAMB1 PHEX PRELP PCDH7 NPNT

6.87e-062001567dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATAD5 WDR18 SP110 DHCR7 PKN1 TIMELESS

2.08e-051591566e9c51e611ebd427bbe51e3e036c14122c36ea372
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HLA-DOB SP110 TNFRSF13B HAAO IL1RL1 UNC93B1

2.31e-05162156659f6a9005c4f22f084c25ea36f3cacce5144a9ae
ToppCellBasal_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 EPPK1 SCGN ARL4D MMP1 PCDH7

2.48e-05164156685487a303194f5244956ec1ca2d1758d38117f41
ToppCell-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MXRA5 CD248 HLA-DOB MFAP5 IGHA2 TNFRSF13B

2.65e-051661566bc9323de1373fdc0357e6bb46874f6c4787443a9
ToppCellfacs-Heart-LV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 NUP210L LAMB1 EGFR PRELP IGSF3

2.93e-051691566849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCellfacs-Trachea-nan-18m-Myeloid|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DOB NRROS TNFRSF13B HAAO UNC93B1 ADAP2

3.13e-0517115669d496a6edac9663791cda684188d49895246f6fe
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 TECTA OVCH1 SNED1 MFAP5 PRELP

3.23e-051721566e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HLA-DOB TWF2 NRROS HAAO TIMELESS UNC93B1

3.23e-051721566eaba10a4d4eaab42ad2e2da65ebb20b50edaf815
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA2D1 PDE3A MYLK SACS PCDH7 CNN1

3.34e-051731566cb6389536195443633adb06e5f1b7483530773d1
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 SLC28A3 EGFR LRP2 MSLN IGSF3

3.34e-051731566e05cddf5bf63cf419343ff229453327519765be8
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 SLC28A3 EGFR LRP2 MSLN IGSF3

3.34e-05173156674ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYLK ING1 MFAP5 IGHA2 PRELP CNN1

3.56e-051751566c6c0196875f3b5293083cda6718300806a801941
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYLK ING1 MFAP5 IGHA2 PRELP CNN1

3.56e-05175156682c4d1edaa0d3b82d3ef4676d6f6516104a2656a
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 MXRA5 MYLK LAMB1 PRELP NPNT

3.80e-0517715668220cc2fc0ee8764a67a3be51d75248be2453040
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 ABCA1 SLFN5 FAM170B PRELP ADAP2

3.80e-05177156626bad614560609d318bfc9c235a698bca4e1c22c
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 MXRA5 MYLK LAMB1 PRELP NPNT

3.80e-0517715667617270f49cd6b7ba66db72d20560cee985012b2
ToppCellSevere-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HLA-DPB1 ARL4D PHEX MFAP5 CLEC2D ADAP2

3.92e-051781566b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CETP HLA-E HLA-F SNED1 DCHS1 SLFN11

3.92e-051781566375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 GRB7 SLC28A3 MFAP5 ZMYND10 EGFR

4.30e-051811566e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 GRB7 SLC28A3 MFAP5 ZMYND10 EGFR

4.30e-05181156635eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA2D1 MYLK LAMB1 PRELP CNN1 NPNT

4.30e-051811566b116c68393d8836bac080f81a8fcbeb52e0403e7
ComputationalGenes in the cancer module 104.

KIF21B ABCA1 CYP2E1 ING1 HLA-DOB SCGN PGC FAT2 PPT2 TNFRSF13B HAAO MPZL2

7.54e-053539712MODULE_104
ComputationalGenes in the cancer module 181.

KIF21B ABCA1 CYP2E1 ING1 SCGN PGC FAT2 PPT2 TNFRSF13B HAAO MPZL2

9.35e-053069711MODULE_181
ComputationalGenes in the cancer module 143.

HLA-DOB HLA-E HLA-F

2.41e-0414973MODULE_143
Diseasethoracic aortic aneurysm (is_implicated_in)

MYLK MFAP5 MMP1

2.06e-05111503DOID:14004 (is_implicated_in)
DiseaseC-C motif chemokine 16 measurement

MMP28 SLFN5 SLFN11

2.74e-05121503EFO_0008044
Diseasefamilial hyperlipidemia (biomarker_via_orthology)

ABCA1 CYP2E1 SLC27A1

1.18e-04191503DOID:1168 (biomarker_via_orthology)
Diseaseoccupational asthma (is_implicated_in)

HLA-DPB1 HLA-E

1.53e-0441502DOID:0080820 (is_implicated_in)
Diseasetendinitis (biomarker_via_orthology)

MMP1 LRP5L

3.80e-0461502DOID:971 (biomarker_via_orthology)
DiseaseREM sleep behavior disorder

TMEM175 INPP5F

3.80e-0461502EFO_0007462
Diseasethyroid peroxidase antibody measurement

TPO HLA-DOB HLA-DPB1 TRIM60

5.05e-04721504EFO_0005666
Diseasegraft-versus-host disease (implicated_via_orthology)

HLA-E HLA-F

5.30e-0471502DOID:0081267 (implicated_via_orthology)
Diseasefatty liver disease (biomarker_via_orthology)

ABCC3 ABCA1 CYP2E1

6.28e-04331503DOID:9452 (biomarker_via_orthology)
Diseaseamino acid measurement

CACNA2D1 PRSS55 LAMB1 MMP25 NELL2 ACAD8 ABCB8 LRP2 PKN1 PRKDC MGAM2

7.25e-0467815011EFO_0005134
Diseaseaspartate aminotransferase measurement

KIF21B ARHGEF19 PDE3A ABCA1 HLA-DPB1 CETP PELI2 POLR2M INPP5F GBA3 CNNM1 MOCOS CD276

7.43e-0490415013EFO_0004736
DiseaseHypercholesterolemia

ABCA1 MYLK CETP

1.03e-03391503C0020443
DiseaseHuman papillomavirus infectious disease (is_marker_for)

EGFR IL1RL1

1.12e-03101502DOID:11166 (is_marker_for)
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

MYLK MFAP5

1.12e-03101502cv:C4707243
Diseaseinterstitial collagenase measurement

MMP25 MMP1

1.37e-03111502EFO_0008193
Diseasecoronary artery disease (is_implicated_in)

ABCA1 MYLK IL1RL1 MMP1

1.72e-031001504DOID:3393 (is_implicated_in)
DiseaseHyperlipoproteinemia Type IIb

ABCA1 CETP

1.93e-03131502C1704417
Diseasecortisol measurement, response to corticosteroid, response to synacthen

SCGN GBA3

1.93e-03131502EFO_0005843, EFO_0009175, GO_0031960
Diseasesevere acute respiratory syndrome, COVID-19

ABCC3 CACNA2D1 MXRA5 ZNF212 ZNF213 POLR2M SLFN5 LRP5L

2.11e-034471508EFO_0000694, MONDO_0100096
DiseaseMetabolic Bone Disorder

DHCR7 LRP2

2.24e-03141502C0005944
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

ABCA1 LRP2

2.24e-03141502DOID:10976 (biomarker_via_orthology)
DiseaseOsteopenia

DHCR7 LRP2

2.58e-03151502C0029453
Diseaselevel of Phosphatidylcholine (16:0_16:0) in blood serum

CETP PPT2

2.58e-03151502OBA_2045067
DiseaseHyperlipoproteinemia Type IIa

ABCA1 CETP

2.94e-03161502C0745103
Diseaseidiopathic scoliosis (implicated_via_orthology)

MBTPS1 ZMYND10

2.94e-03161502DOID:0060250 (implicated_via_orthology)
Diseasephosphorus measurement

NBPF3 PHEX

2.94e-03161502EFO_0004861
DiseaseCarcinoma, Granular Cell

CYP2E1 GRB7 EGFR MSLN

2.96e-031161504C0205644
DiseaseAdenocarcinoma, Tubular

CYP2E1 GRB7 EGFR MSLN

2.96e-031161504C0205645
DiseaseAdenocarcinoma, Oxyphilic

CYP2E1 GRB7 EGFR MSLN

2.96e-031161504C0205642
DiseaseCarcinoma, Cribriform

CYP2E1 GRB7 EGFR MSLN

2.96e-031161504C0205643
DiseaseAdenocarcinoma, Basal Cell

CYP2E1 GRB7 EGFR MSLN

2.96e-031161504C0205641
DiseaseAdenocarcinoma

CYP2E1 GRB7 EGFR MSLN

2.96e-031161504C0001418
DiseaseColorectal Carcinoma

ABCC3 ABCA1 CD248 WNT8B EGFR SACS TENM1 DCHS1 LRP2 MMP1

3.24e-0370215010C0009402
DiseaseAtherosclerosis

ABCA1 CETP MMP1

3.40e-03591503C0004153
DiseaseAtherogenesis

ABCA1 CETP MMP1

3.40e-03591503C1563937
DiseaseUterine leiomyoma, estrogen-receptor positive breast cancer

ATAD5 ADAP2

3.72e-03181502EFO_1000649, HP_0000131
DiseaseHypercholesterolemia, Familial

ABCA1 CETP

3.72e-03181502C0020445
DiseaseHDL cholesterol change measurement, physical activity

ABCA1 CETP MRM1

3.91e-03621503EFO_0003940, EFO_0007805
Diseasewhite matter microstructure measurement

CACNA2D1 EPPK1 POLR2M SCGN EGFR LRP2 SUZ12

3.91e-033901507EFO_0005674
Diseasechronic obstructive pulmonary disease (is_implicated_in)

CYP2E1 HLA-DPB1 MMP1

4.09e-03631503DOID:3083 (is_implicated_in)
Diseaseresponse to methotrexate, neurotoxicity

PKN1 KAZALD1

4.15e-03191502EFO_0011057, GO_0031427
DiseaseMalignant Neoplasms

DNAJC10 EGFR SUZ12 MSLN

4.20e-031281504C0006826
DiseaseProstatic Neoplasms

MBTPS1 CYP2E1 ARHGEF5 GRB7 DNAJC10 EGFR LRP2 PRKDC CD276

4.38e-036161509C0033578
DiseaseMalignant neoplasm of prostate

MBTPS1 CYP2E1 ARHGEF5 GRB7 DNAJC10 EGFR LRP2 PRKDC CD276

4.38e-036161509C0376358
DiseaseAlcohol abuse

CYP2E1 EGFR ALDH1A1

4.86e-03671503C0085762
DiseaseInfiltrating duct carcinoma of female breast

SMG1 PKN1

5.06e-03211502C3165106
Diseaseesophagus adenocarcinoma (is_implicated_in)

GRB7 MMP1

5.06e-03211502DOID:4914 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
RQLGVGAFPVESRWQ

ALS2CL

586

Q60I27
QFWIRSGGGVLEERP

ATAD5

1401

Q96QE3
SVKEPQLVWGGDANR

ARID5A

381

Q03989
SIGEWFGPNTVAQVL

ATG4A

141

Q8WYN0
LQGEREPGWIKQLFT

CETP

171

P11597
NEFGTIIDWAPRGQF

ERVK-18

146

O42043
NEFGTIIDWTPQGQF

ERVK-9

256

Q9UKH3
WSPQGQFVVLAGLRS

EIF3B

616

P55884
SNLLWDTGVFRGPVL

APOBEC3D

46

Q96AK3
TFQVWDVGGQEKLRP

ARL4D

71

P49703
VGWNSQPTRAVIFED

ACAD8

236

Q9UKU7
GVRAWVKENRGSFQP

HAAO

6

P46952
VRLSDGERGWFPVQQ

ARHGEF5

1551

Q12774
GERGWFPVQQVEFIS

ARHGEF5

1556

Q12774
LQRPLRGFTWTTGDQ

CD248

96

Q9HCU0
GIGVQWDNLFESPVE

ABCA1

801

O95477
GENRFVSPLSWDLVG

ABCA1

1836

O95477
RWSGSGFINFQEVPV

ADGRV1

3436

Q8WXG9
PGSIQVRWFLNGQEE

HLA-DPB1

151

P04440
GLWNFPFGTIRQESQ

BIVM

426

Q86UB2
WADKIQGRTIPIDGN

ALDH1A1

136

P00352
TQFAPGQWAGVVLDD

CLIP2

101

Q9UDT6
EAEVFWQDGQGVPLT

CD276

391

Q5ZPR3
GRPGIVAWTLINLSF

DHCR7

241

Q9UBM7
AQGWKQRLAEGEFTP

ASXL3

316

Q9C0F0
GETISLPGNREGFLW

ADAP2

126

Q9NPF8
LQRPFGQRVESIGQW

ANO8

791

Q9HCE9
RGPIKFNVWDTAGQE

RAN

56

P62826
DRGIIFNNGPTWKDI

CYP2E1

111

P05181
LVETRPAGDGTFQKW

HLA-F

251

P30511
WEPSFLKQVEGIRQG

ABCC3

506

O15438
TFSLWQDIPDVRGSG

ARHGEF19

351

Q8IW93
EVWSTQQGPRVGAFN

RAB3GAP2

476

Q9H2M9
SGPQFWVFQDRQLEG

MMP25

386

Q9NPA2
SIISGNWGRVFQLEP

DCHS1

2521

Q96JQ0
LVETRPAGDGTFQKW

HLA-E

251

P13747
AWFLEGTPVRRQEGS

MYLK

446

Q15746
FTEDVGQLPGLTIWQ

FLII

491

Q13045
DDGTPRIVTNLGLQW

FRAS1

2436

Q86XX4
RGGPQRFEVTGWLQI

KAZALD1

226

Q96I82
GWLQIQAVRPSDEGT

KAZALD1

236

Q96I82
GLSEEQLQEPITGWR

LPCAT4

71

Q643R3
TDLPLGTTFWLGQRN

NELL2

181

Q99435
GGANIPALNELLSVW

MBTPS1

751

Q14703
LGQEFSIRWNLPVSD

MGAM2

896

Q2M2H8
FDGRWPRQIVSSIGL

NPNT

21

Q6UXI9
VTQVLGRSPVDFWGA

ENTPD8

146

Q5MY95
ELGLELVFVWNRDPG

ASPDH

31

A6ND91
EFSQILWIGGRNPGE

DDX55

111

Q8NHQ9
LWIGGRNPGEDVERF

DDX55

116

Q8NHQ9
PLGQFGISQVGDEWR

FAT2

2951

Q9NYQ8
AGLEARWTALQEVPG

DLAT

16

P10515
VIGPSQSWVDLFEGQ

PCDH7

116

O60245
PEGWLRLSLNNGSIT

PGAM5

246

Q96HS1
TWNFPIFDLVENIGR

PDE3A

691

Q14432
NIDVWLGGLAENFLP

TPO

631

P07202
WTVTVQELGPFRGIT

CSKMT

216

A8MUP2
SGNAVRIWELSRFQP

KIF21B

1431

O75037
GFSEGLWEIENNPTV

HDGF

81

P51858
VGWSVDFSRPQLGED

HNRNPUL2

316

Q1KMD3
PTDSLQGIILTGWQR

HEXD

286

Q8WVB3
QWLFRELPSQLSGEG

MRS2

161

Q9HD23
RNSGWVFENPSIGVL

LCN6

91

P62502
ELRVLVNASLGWPNG

LRP5L

111

A4QPB2
GSRFWIQDKGPIVES

DPP3

296

Q9NY33
IQDRIPSWTGAGFVR

LAMB1

576

P07942
VTWNFRPLDGGPEQF

MPZL2

61

O60487
GLFNELLENGISVWP

POLG2

401

Q9UHN1
AAFEVTRWPVGNQGL

MOCOS

596

Q96EN8
FSLGWVQPSRTLAGE

MSLN

26

Q13421
NILVFEDLGWPTGLS

LRP2

4221

P98164
SVEVFWPGTIQREGS

FAM170B

31

A6NMN3
EVQAAWPVGGDSRFV

GRB7

166

Q14451
WIPLGVNSQRGDDVT

MFAP5

21

Q13361
GRESLRPLWEQVQGF

PPT2

76

Q9UMR5
TVQGFQWTLRGPDVE

NBPF3

6

Q9H094
ITGFLLIQAWPENRT

EGFR

401

P00533
WQLNGTKITDFGEPR

IL1RL1

251

Q01638
VVSSGRDPQLQGIWF

CD101

306

Q93033
RDPQLQGIWFFNGTE

CD101

311

Q93033
TAGRPQGRFSVIWQL

IGSF3

436

O75054
WQFLSGVTPLNEGVA

CBLIF

386

P27352
TGPIRNGDWTFQTVV

HLA-DOB

171

P13765
QLPSENREGKVLWTG

CENPL

146

Q8N0S6
PAVWQGGETEALARL

CRY2

226

Q49AN0
FDLPQTLEDQGGWLS

GBA3

121

Q9H227
NEFGTIIDWAPRGQF

ERVK-24

146

P61566
VEAPGETFAQRVSWG

POLR2M

66

Q6EEV4
NEFGTIIDWAPRGQF

ERVK-7

146

P61567
NREEDPSLLWQVFGS

CACNA2D1

196

P54289
GEVLLIPQNGFWTLE

BTN2A1

411

Q7KYR7
NEFGTIIDWAPRGQF

ERVK-21

256

P61565
NEFGTIIDWAPRGQF

ERVK-5

146

Q9HDB8
NVTTGSLGEPQWLRV

CLPB

36

Q9H078
GFSPKDVLVRWLQGS

IGHA2

241

P01877
RIWGLGFLPQVSTDL

DNAJC10

661

Q8IXB1
QSPRQGLLQRWEVSG

C1orf127

71

Q8N9H9
LRWVQENIAPFGGDL

CES3

206

Q6UWW8
GFRNWRLLQITGTAP

SLC22A13

246

Q9Y226
EPTLGRLDAAGFWQV

SCGN

6

O76038
QSTGERDGRPLWQKV

INPP5F

191

Q9Y2H2
ETGFPVSEQRLWRGG

SACS

41

Q9NZJ4
ETEQAGVLNWFRVPL

MFSD5

371

Q6N075
WGVLNGSLAPLQDVA

NRROS

496

Q86YC3
FTVQPGNRWSLEVGQ

NUP210L

361

Q5VU65
LDPSWLRGQVVGFIS

ABCB8

541

Q9NUT2
FQWVSQLPVSGVLDR

MMP28

66

Q9H239
GNRLTVLAWVAFQPG

NYX

311

Q9GZU5
AGPVVTDNGNFILDW

RPIA

246

P49247
DVAQFVLTEGNPRWE

MMP1

96

P03956
VRQGEKFLQPLTGWE

PLEKHG4

506

Q58EX7
IVLGPNLLWARNEGT

ARHGAP17

401

Q68EM7
RVDLNVFGSLGLQPW

ING1

51

Q9UK53
LWLVLDGIQDPRNFG

MRM1

146

Q6IN84
FLWERPTLLVLGNEG

MRM1

246

Q6IN84
FSPQWLSRRIAGGEE

OVCH1

566

Q7RTY7
RGGFTEESQPGVWRE

PELI2

196

Q9HAT8
RSGLIQWVDGATPLF

SMG1

2201

Q96Q15
GQFQGRPVSVWDVLF

EPPK1

3181

P58107
RGQFQGRPVSVWDVL

EPPK1

4781

P58107
LEVFPEAEWSQGVQG

SLFN11

761

Q7Z7L1
HLFGLTWQLQPVEGE

TENM1

341

Q9UKZ4
ELPDGQVITIGNEWF

POTEI

941

P0CG38
ELPVESFQNATGLRW

PRELP

116

P51888
GQEWINLRDGPITIS

RNF216

21

Q9NWF9
EGSIFQVDLFTWPGQ

WDR18

236

Q9BV38
GPNAWDQSFTLELER

PKN1

411

Q16512
TDPGFIAFDWLGRQV

SLC28A3

246

Q9HAS3
WLTPNEFEVEGKGRN

SP110

496

Q9HB58
QSRQQRGWVFTPGVD

PMVK

136

Q15126
VEVLGAERFSPQSWG

FAM110D

176

Q8TAY7
QGSRPEGRFSALIWV

EXTL1

411

Q92935
FWRLVDSAEIQPIGN

SCMH1

101

Q96GD3
TTTNVGVPGRWAFRI

SNED1

241

Q8TER0
INGTEWTRQFPILGA

CLEC2D

146

Q9UHP7
EWIEGVTGRRIGNNF

CNN1

36

P51911
ENGTGDWAPRLVFIE

CNNM1

96

Q9NRU3
PATFVGSRQWIGSIE

UFSP2

341

Q9NUQ7
QALGIPIGDWRTQTG

TECTA

576

O75443
SAREVWPEGDVFGSQ

TIMELESS

621

Q9UNS1
TQTCWLQLPEFREVG

WNT8B

191

Q93098
EIDLRSVGWGNIFQL

UNC93B1

316

Q9H1C4
LPTGIEGNWGRLLEQ

ZBED2

131

Q9BTP6
QAETLQPSVWFGGRE

TMEM175

401

Q9BSA9
AEGLWEQGFLRTPEQ

ZSCAN32

291

Q9NX65
NGQPLWILGDVFLRS

PGC

356

P20142
AVGNGLRPAIWEEFT

SLC27A1

361

Q6PCB7
QLGGAPNRWEVLSAT

SP3

101

Q02447
QGPTLQFTLRWTGET

SUZ12

351

Q15022
FSREEWGLLGPTQRT

ZNF274

296

Q96GC6
WVGEFSLSVGPQREA

TNKS1BP1

1086

Q9C0C2
ESNIGPEGVWSERKF

PHEX

171

P78562
LLRNWQDQPSVLGGF

TRIM60

371

Q495X7
QEGSLSARWPVAGQI

PRKDC

2621

P78527
VGEFPWQVSIQARSE

PRSS55

76

Q6UWB4
ERTALFWVEAAGQGP

UBAP1L

46

F5GYI3
DQEERFPQGLWTGVA

TNFRSF13B

16

O14836
EQFLTVLPGEIQGWV

ZNF213

91

O14771
IGENLSRGDDWIPSF

ZNF548

126

Q8NEK5
QAFLSPEQTELWGGQ

ZNF212

241

Q9UDV6
SPWSRREGGKLQQFE

ZMYND10

226

O75800
RVEGGVRPLFWSTNE

ZNF589

146

Q86UQ0
LGQFASLGPVSVWRI

SLC6A14

96

Q9UN76
FVNRGGLPVDEATWE

VASH1

61

Q7L8A9
KFITQTARDGPGVLW

SLFN5

666

Q08AF3
QLVLGASQEPVGRWD

TWF2

36

Q6IBS0
QRLQWEVSFELGTPG

VWA5B1

821

Q5TIE3
WAVQGRPFEVRTGTL

SLC8A2

841

Q9UPR5
WVLGDGTQIRPSQFL

MXRA5

2081

Q9NR99
NFVGDWPVDKTIGQR

N4BP2

786

Q86UW6