Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	apical junction complex	EPPK1 FRMD4B MAGI2 TBCD SHROOM3 PLXDC1 APC ILDR1 CTNND1 MTDH	2.08e-06	158	192	10	GO:0043296
GeneOntologyCellularComponent	bicellular tight junction	EPPK1 FRMD4B MAGI2 TBCD PLXDC1 APC ILDR1 CTNND1 MTDH	3.48e-06	131	192	9	GO:0005923
GeneOntologyCellularComponent	tight junction	EPPK1 FRMD4B MAGI2 TBCD PLXDC1 APC ILDR1 CTNND1 MTDH	5.66e-06	139	192	9	GO:0070160
GeneOntologyCellularComponent	cell-cell junction	DCHS2 EPPK1 OBSCN FRMD4B MAGI2 FAT2 TBCD SHROOM3 PLXDC1 APC PDLIM1 ILDR1 POLDIP2 CTNND1 MTDH	3.85e-04	591	192	15	GO:0005911
Domain	USP_1	USP17L7 USP19 USP17L4 USP17L2 USP8 USP17L8	8.05e-05	70	191	6	PS00972
Domain	UCH	USP17L7 USP19 USP17L4 USP17L2 USP8 USP17L8	8.72e-05	71	191	6	PF00443
Domain	USP_2	USP17L7 USP19 USP17L4 USP17L2 USP8 USP17L8	8.72e-05	71	191	6	PS00973
Domain	USP_3	USP17L7 USP19 USP17L4 USP17L2 USP8 USP17L8	9.43e-05	72	191	6	PS50235
Domain	USP_dom	USP17L7 USP19 USP17L4 USP17L2 USP8 USP17L8	9.43e-05	72	191	6	IPR028889
Domain	Peptidase_C19_UCH	USP17L7 USP19 USP17L4 USP17L2 USP8 USP17L8	9.43e-05	72	191	6	IPR001394
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	EPPK1 MTHFD2 PRPF6 TIPRL PYGB PLRG1 IMMT SEC23A TBCD GRWD1 GEMIN5 RECQL GSPT1 CS PDLIM1 UBA6 PRKCSH POLDIP2 CTNND1 CTPS1 SNRNP200 MTDH	4.88e-12	607	194	22	39147351
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	USP17L7 UIMC1 THNSL1 PRPF6 CHD4 USP19 PLRG1 IMMT NUP153 SFXN4 ITCH USP17L2 NEDD4L APC YTHDC2 CERT1 CBR3 USP8 UBE2O CS NUP188 DCAF11 CTNND1 SNRNP200 MTDH TNPO3 PPP6R3	1.62e-11	1005	194	27	19615732
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	VPS13C FRMD4B TIAM2 SYNJ2 CASP8AP2 SHROOM3 SASH1 UVSSA HECTD4 G2E3 LRRK1 CLOCK UBE2O CDK5RAP2 FAM53B SCAF11 NUP188 PPP6R3	1.27e-09	529	194	18	14621295
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GBF1 KIF1A VPS13C PRPF6 CHD4 GTF3C3 USP19 DDX50 PI4KA PLRG1 IMMT SEC23A NUP153 NPAS2 GRWD1 GEMIN5 RECQL YTHDC2 GSPT1 UBE2O CS UBA6 PRKCSH NUP188 POLDIP2 CTNND1 CTPS1 SNRNP200 MTDH	1.79e-09	1425	194	29	30948266
Pubmed	A protein interaction landscape of breast cancer.	UIMC1 EPPK1 GBF1 MTHFD2 DDX50 PI4KA GOLIM4 NUP153 MTF2 MYO19 GSPT1 CHEK2 PPP1R18 SCAF11 NUP188 CTNND1 MTDH TNPO3 PPP6R3	3.47e-09	634	194	19	34591612
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DCHS2 WDR4 KIF1A TRPM7 CHD4 NCAPH2 FRMD4B MAGI2 SCG2 MTMR3 CHD6 CARS2 IMMT ITCH HECTD4 APC DYNC2I1 CBR3 SLC4A3 ADAM22 ARHGAP5 USP8 UBE2O CS METTL8 POLDIP2 SNRNP200	3.53e-09	1285	194	27	35914814
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	WDR4 KIF1A NUMBL PLCXD1 VPS13C OBSCN KATNAL1 SYNJ2 CHD6 DENND5A CAMTA1 SCARA3 TBCD NPAS2 SHROOM3 ITCH NEDD4L UVSSA HECTD4 HIPK2 DYNC2I1 RNF213 G2E3 ZHX2 CERT1 UBA6 SCAF11 CTNND1 MBD5	4.79e-09	1489	194	29	28611215
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	USP17L7 OLAH KIF1A VPS13C HLA-G OBSCN PHF8 PI4KA PKHD1 CHD6 IPPK MXRA5 MYO19 RNF213 ARHGAP5 PDLIM1 NUP188 POTEA CTPS1 SNRNP200	6.85e-09	736	194	20	29676528
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	GBF1 PRPF6 CHD4 GTF3C3 USP19 PLRG1 IMMT SEC23A NUP153 GRWD1 GEMIN5 GSPT1 UBE2O NUP188 CTPS1 SNRNP200 TNPO3 PPP6R3	2.30e-08	638	194	18	33239621
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	GBF1 KIF1A NCAPH2 TIPRL PTPRO MTMR3 GOLIM4 IMMT QSOX2 NUP153 SFXN4 RANBP6 YTHDC2 PSTPIP2 UBE2O MTMR4 PRKCSH NUP188 SNRNP200 MTDH TNPO3 PPP6R3	3.19e-08	974	194	22	28675297
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	SYNJ2 SHROOM3 ITCH NEDD4L SASH1 APC USP8 FAM53B	1.14e-07	102	194	8	15778465
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	EPPK1 KIF1A PRPF6 CHD4 GTF3C3 PYGB IMMT SEC23A NUP153 GEMIN5 RECQL YTHDC2 UBE2O SCAF11 NUP188 SNRNP200 PPP6R3	1.79e-07	653	194	17	22586326
Pubmed	High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.	USP17L7 USP17L4 USP17L2 USP17L8	1.92e-07	10	194	4	24207026
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPPK1 GBF1 OBSCN ST14 TIAM2 PI4KA MTMR3 PYGB DENND5A SCARA3 TBCD CRYBG2 SHROOM3 HECTD4 GEMIN5 GRID1 LRRK1 ZNF263 NUP188 STK40 MBD5 TNPO3	2.80e-07	1105	194	22	35748872
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	THNSL1 TRPM7 MTHFD2 VPS13C ACSS1 USP19 DDX50 PI4KA MTMR3 CARS2 IMMT SEC23A SFXN4 MYO19 DYNC2I1 RANBP6 RNF213 YTHDC2 LARP1B CS AKAP9 CDK5RAP2 PRKCSH NUP188 POLDIP2 MTDH	2.99e-07	1496	194	26	32877691
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	UIMC1 MAP1A NUMBL CHD4 TIPRL DDX50 PLRG1 NUP153 NOL8 PARG GEMIN5 YTHDC2 USP8 UBE2O PDLIM1 CTNND1 CTPS1 SNRNP200 MTDH PPP6R3	3.26e-07	934	194	20	33916271
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	EPPK1 PRPF6 CHD4 GOLIM4 CARS2 PLRG1 IMMT MOCS2 SEC23A GRWD1 NEDD4L GEMIN5 RECQL TSSC4 GSPT1 USP8 UBE2O UBA6 SCAF11 POLDIP2 CTNND1 CTPS1 SNRNP200 MTDH PPP6R3	3.82e-07	1415	194	25	28515276
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GBF1 NUMBL TRPM7 SYNJ2 PI4KA SHROOM3 ITCH NEDD4L SASH1 APC LARP1B RFX7 USP8 MTMR4 AKAP9 FAM53B CTNND1 TNPO3 OTOG	4.17e-07	861	194	19	36931259
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TRPM7 CCDC30 VPS13C CHD4 GTF3C3 USP19 DDX50 PI4KA SEC23A NOL8 SHROOM3 APC RNF213 GPRIN3 CDK5RAP2 CTNND1 SNRNP200 MTDH	4.25e-07	777	194	18	35844135
Pubmed	Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.	USP17L7 USP17L4 USP17L2 USP17L8	4.49e-07	12	194	4	24695638
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NUMBL CHD4 MAGI2 KIF3B PI4KA SEC23A NUP153 SHROOM3 ITCH NEDD4L HECTD4 APC PEX5L ADAM22 ZNF263 UBE2O AKAP9 UBA6 CDK5RAP2 CTNND1	5.26e-07	963	194	20	28671696
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	TIPRL DDX50 DENND5A TAF1L NUP153 NOL8 YTHDC2 PDLIM1 SCAF11 SNRNP200 MTDH	6.30e-07	283	194	11	30585729
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	EPPK1 GBF1 MTHFD2 PRPF6 CHD4 TIPRL USP19 GOLIM4 PYGB PLRG1 IMMT SEC23A TBCD ITCH GEMIN5 RNF213 CP RECQL GSPT1 UBE2O CS UBA6 PRKCSH CTPS1	7.45e-07	1367	194	24	32687490
Pubmed	ES cell neural differentiation reveals a substantial number of novel ESTs.	USP17L7 USP17L4 USP17L2 USP17L8	8.99e-07	14	194	4	11793228
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	WDR4 PRPF6 CHD4 GTF3C3 DDX50 NUP153 HECTD4 APC GEMIN5 YTHDC2 NUP188 CTNND1 PPP6R3	1.32e-06	440	194	13	34244565
Pubmed	CLOCK gene variants associate with sleep duration in two independent populations.	PER3 NPAS2 CLOCK	1.69e-06	5	194	3	20149345
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	UIMC1 GBF1 CHD4 PHF8 USP19 NUP153 PARG GEMIN5 YTHDC2 TSSC4 RFX7 PPP1R18 SCAF11 CTPS1 SNRNP200 ZHX1 PPP6R3	1.85e-06	774	194	17	15302935
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	NUMBL PHF8 TIPRL DDX50 PI4KA MTMR3 GOLIM4 NUP153 PPM1D RNF213 GPRIN3 PSTPIP2 ARHGAP5 MTMR4 AKAP9 PPP1R18 CDK5RAP2 PRKCSH CTNND1 PPP6R3	1.95e-06	1049	194	20	27880917
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	NUMBL TRPM7 PRPF6 GTF3C3 PI4KA CARS2 PLRG1 IMMT NOL8 CASP8AP2 SHROOM3 ITCH GRWD1 SLC4A2 UBE2O AKAP9 UBA6 CDK5RAP2 PRKCSH POLDIP2 CTNND1 SNRNP200 MTDH PPP6R3	3.20e-06	1487	194	24	33957083
Pubmed	CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.	USP17L7 USP17L4 USP17L2 USP17L8	3.41e-06	19	194	4	28067227
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	UIMC1 SPTA1 PRPF6 CHD4 NCAPH2 PHF8 DDX50 CHD6 TAF1L PLRG1 NUP153 NOL8 CASP8AP2 GRWD1 MTF2 G2E3 RFX7 CLOCK SCAF11 NUP188 SNRNP200 MTDH	3.74e-06	1294	194	22	30804502
Pubmed	DUB-1, a deubiquitinating enzyme with growth-suppressing activity.	USP17L7 USP17L4 USP17L2 USP17L8	5.22e-06	21	194	4	8622927
Pubmed	ARRDC1 and ARRDC3 act as tumor suppressors in renal cell carcinoma by facilitating YAP1 degradation.	ITCH NEDD4L UBE2O TNFRSF1A	5.22e-06	21	194	4	29416926
Pubmed	DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.	USP17L7 USP17L4 USP17L2 USP17L8	5.22e-06	21	194	4	14583620
Pubmed	DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.	USP17L7 USP17L4 USP17L2 USP17L8	5.22e-06	21	194	4	11468161
Pubmed	The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.	USP17L7 USP17L4 USP17L2 USP17L8	5.22e-06	21	194	4	8756639
Pubmed	Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.	USP17L7 USP17L4 USP17L2 USP17L8	5.22e-06	21	194	4	12447969
Pubmed	DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.	USP17L7 USP17L4 USP17L2 USP17L8	5.22e-06	21	194	4	18980247
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	EPPK1 PRPF6 CHD4 TRUB1 PLRG1 SEC23A NUP153 SHROOM3 PPM1D YTHDC2 PSTPIP2 GSPT1 CTNND1 SNRNP200	5.59e-06	582	194	14	20467437
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	EPPK1 VPS13C CHD4 TIAM2 PI4KA ZSCAN2 CHD6 PLRG1 IMMT CASP8AP2 SHROOM3 USP8 CS CTPS1 SNRNP200 MTDH	5.81e-06	754	194	16	35906200
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	KIF1A GTF3C3 USP19 PI4KA GOLIM4 IMMT QSOX2 SEC23A NUP153 TBCD SFXN4 ITCH RANBP6 SLC4A2 UBE2O NUP188 TNPO3 PPP6R3	6.33e-06	942	194	18	31073040
Pubmed	JAK2 is required for induction of the murine DUB-1 gene.	USP17L7 USP17L4 USP17L2 USP17L8	6.35e-06	22	194	4	9154835
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP17L7 USP19 USP17L4 USP17L2 USP8 USP17L8	6.39e-06	81	194	6	12838346
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	STARD13 HLA-G PRPF6 CHD4 EPB41L4A MAGI2 AEBP1 GOLIM4 CARS2 IMMT QSOX2 SEC23A P3H3 RNF213 CP SLC4A2 CS AKAP9 PRKCSH POLDIP2 CTPS1 SNRNP200 MTDH	6.99e-06	1451	194	23	30550785
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	GBF1 WDR4 USP19 PYGB SEC23A TBCD RANBP6 GEMIN5 RECQL CERT1 GSPT1 USP8 UBE2O CS PDLIM1 UBA6 PRKCSH NUP188 DCAF11 CTPS1 SNRNP200 TNPO3 PPP6R3	7.31e-06	1455	194	23	22863883
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	EPPK1 GBF1 SPTA1 OBSCN PRPF6 CHD4 PI4KA RNF213 DCAF11 SNRNP200	8.97e-06	304	194	10	32235678
Pubmed	DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.	USP17L7 USP17L4 USP17L2 USP17L8	9.14e-06	24	194	4	8995226
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	MTHFD2 CHD4 TIPRL TRUB1 USP19 PYGB IMMT QSOX2 SEC23A TBCD SHROOM3 GRWD1 CBR3 GSPT1 PRKCSH CTPS1 PPP6R3	9.75e-06	878	194	17	37223481
Pubmed	Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.	USP17L7 USP17L4 USP17L2 USP17L8	1.08e-05	25	194	4	21115691
Pubmed	Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.	USP17L7 USP17L4 USP17L2 USP17L8	1.27e-05	26	194	4	35816173
Pubmed	Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesis.	PPM1D APC CHEK2	1.40e-05	9	194	3	22555459
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	EPPK1 PRPF6 CHD4 DDX50 PI4KA IMMT SEC23A NUP153 NEDD4L YTHDC2 CS PDLIM1 UBA6 PRKCSH NUP188 CTNND1 SNRNP200 MTDH	1.93e-05	1024	194	18	24711643
Pubmed	Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder.	PER3 NPAS2 CLOCK	1.99e-05	10	194	3	16528748
Pubmed	Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study.	PER3 NPAS2 CLOCK	1.99e-05	10	194	3	19934327
Pubmed	Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.	USP17L7 USP17L4 USP17L2 USP17L8	2.00e-05	29	194	4	32527007
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PHF8 USP19 MAGI2 KIF3B MTMR3 CHD6 CAMTA1 NEDD4L ZHX2 USP8 AKAP9	2.00e-05	407	194	11	12693553
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	STARD13 PRPF6 CHD4 PHF8 GTF3C3 DDX50 PI4KA PYGB PLRG1 IMMT SEC23A ITCH MYO19 GEMIN5 RECQL TSSC4 GSPT1 CS CTNND1 CTPS1 SNRNP200	2.45e-05	1353	194	21	29467282
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	PRPF6 CHD4 GTF3C3 SEC23A CTPS1 SNRNP200 PPP6R3	2.57e-05	153	194	7	26365490
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	GBF1 KIF1A TRPM7 VPS13C PI4KA IMMT SEC23A ITCH ADAM22 SLC4A2 CTNND1 MTDH	2.92e-05	504	194	12	34432599
Pubmed	Functional proteomics mapping of a human signaling pathway.	STARD13 UIMC1 KIF3B CHD6 TBCD NEDD4L SASH1 MTF2 RANBP6 ARHGAP5 MTMR4 UBA6 TNPO3	3.09e-05	591	194	13	15231748
Pubmed	Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.	TCF7 APC	3.10e-05	2	194	2	10489374
Pubmed	CHD chromatin remodelling enzymes and the DNA damage response.	CHD4 CHD6	3.10e-05	2	194	2	23954449
Pubmed	p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia.	APC CTNND1	3.10e-05	2	194	2	29130932
Pubmed	Downregulation of HIPK2 increases resistance of bladder cancer cell to cisplatin by regulating Wip1.	PPM1D HIPK2	3.10e-05	2	194	2	24846322
Pubmed	Interaction of p190RhoGAP with C-terminal domain of p120-catenin modulates endothelial cytoskeleton and permeability.	ARHGAP5 CTNND1	3.10e-05	2	194	2	23653363
Pubmed	WIP1, a homeostatic regulator of the DNA damage response, is targeted by HIPK2 for phosphorylation and degradation.	PPM1D HIPK2	3.10e-05	2	194	2	23871434
Pubmed	Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development.	GBF1 CERT1	3.10e-05	2	194	2	21909260
Pubmed	Clock gene Per3 deficiency disrupts circadian alterations of gut microbiota in mice.	PER3 CLOCK	3.10e-05	2	194	2	37964605
Pubmed	Do Caucasian and Asian clocks tick differently?	PER3 CLOCK	3.10e-05	2	194	2	19967263
Pubmed	The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.	PPM1D CHEK2	3.10e-05	2	194	2	16936775
Pubmed	Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma.	ACSS1 CS	3.10e-05	2	194	2	27363021
Pubmed	Circadian clock-related polymorphisms in seasonal affective disorder and their relevance to diurnal preference.	PER3 NPAS2	3.10e-05	2	194	2	12655319
Pubmed	Circadian rhythm genes CLOCK and PER3 polymorphisms and morning gastric motility in humans.	PER3 CLOCK	3.10e-05	2	194	2	25775462
Pubmed	Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size.	SYNJ2 PI4KA	3.10e-05	2	194	2	24077433
Pubmed	Effects of Occupational Stress and Circadian CLOCK Gene Polymorphism on Sleep Quality of Oil Workers in Xinjiang, China.	PER3 CLOCK	3.10e-05	2	194	2	32737280
Pubmed	The phosphatidylinositol 4-kinase PI4KIIIalpha is required for the recruitment of GBF1 to Golgi membranes.	GBF1 PI4KA	3.10e-05	2	194	2	20530568
Pubmed	The association of CLOCK gene T3111C polymorphism and hPER3 gene 54-nucleotide repeat polymorphism with Chinese Han people schizophrenics.	PER3 CLOCK	3.10e-05	2	194	2	20364331
Pubmed	Human intestinal anion exchanger isoforms: expression, distribution, and membrane localization.	SLC4A3 SLC4A2	3.10e-05	2	194	2	11248201
Pubmed	Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency.	TCF7 APC	3.10e-05	2	194	2	12226748
Pubmed	Clock genes associate with white matter integrity in depressed bipolar patients.	PER3 CLOCK	3.10e-05	2	194	2	27996307
Pubmed	An IκB Kinase-Regulated Feedforward Circuit Prolongs Inflammation.	ITCH TNFRSF1A	3.10e-05	2	194	2	26190110
Pubmed	Intrinsic kinase activity and SQ/TQ domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1.	PPM1D CHEK2	3.10e-05	2	194	2	16798742
Pubmed	Clock 3111 T/C and Period3 VNTR gene polymorphisms and proteins, and melatonin levels in women with infertility.	PER3 CLOCK	3.10e-05	2	194	2	36847953
Pubmed	The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G.	HLA-G PHF8	3.10e-05	2	194	2	30758047
Pubmed	Association between the CLOCK gene 3111 T > C polymorphism and an irregular menstrual cycle in Korean adolescents.	PER3 CLOCK	3.10e-05	2	194	2	26453284
Pubmed	Association between restless legs syndrome and CLOCK and NPAS2 gene polymorphisms in schizophrenia.	NPAS2 CLOCK	3.10e-05	2	194	2	24824748
Pubmed	cDNA cloning and tissue distribution of mRNAs for two proteins that are related to the band 3 Cl-/HCO3- exchanger.	SLC4A3 SLC4A2	3.10e-05	2	194	2	2294114
Pubmed	NEDD4L represses prostate cancer cell proliferation via modulating PHF8 through the ubiquitin-proteasome pathway.	PHF8 NEDD4L	3.10e-05	2	194	2	36136271
Pubmed	Defining the membrane proteome of NK cells.	GBF1 MFSD6 HLA-G PRPF6 CHD4 NCAPH2 KIF3B DDX50 PI4KA GOLIM4 PYGB IMMT ITCH GEMIN5 RNF213 RECQL SLC4A2 NUP188 CTPS1	3.25e-05	1168	194	19	19946888
Pubmed	Cdc25A and Dub3 in a high-stakes balancing act.	USP17L7 USP17L4 USP17L2 USP17L8	3.38e-05	33	194	4	20228807
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	UIMC1 KIF1A NUMBL HLA-G DDX50 PI4KA GOLIM4 CHD6 TAF1L IMMT NOL8 SHROOM3 GRWD1 APC GEMIN5 YTHDC2 ZHX2 ZNF277 PPP1R18 SCAF11 ZHX1 PPP6R3	3.54e-05	1497	194	22	31527615
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	CHD4 GTF3C3 DDX50 IMMT SFXN4 GRWD1 SNRNP200 MTDH	3.66e-05	221	194	8	29991511
Pubmed	The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.	USP17L7 USP17L4 USP17L2 USP17L8	3.82e-05	34	194	4	20403174
Pubmed	DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.	USP17L7 USP17L4 USP17L2 USP17L8	3.82e-05	34	194	4	14699124
Pubmed	The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.	USP17L7 USP17L4 USP17L2 USP17L8	3.82e-05	34	194	4	15780755
Pubmed	USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.	USP17L7 USP17L4 USP17L2 USP17L8	3.82e-05	34	194	4	19188362
Pubmed	Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.	USP17L7 USP17L4 USP17L2 USP17L8	3.82e-05	34	194	4	11941478
Pubmed	Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.	USP17L7 USP17L4 USP17L2 USP17L8	3.82e-05	34	194	4	17109758
Pubmed	The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.	USP17L7 USP17L4 USP17L2 USP17L8	3.82e-05	34	194	4	20388806
Pubmed	Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.	USP17L7 USP17L4 USP17L2 USP17L8	3.82e-05	34	194	4	20715989
Interaction	RNF123 interactions	USP17L7 OLAH KIF1A VPS13C HLA-G OBSCN PHF8 USP19 PI4KA PKHD1 CHD6 IPPK MXRA5 MYO19 RNF213 ARHGAP5 PDLIM1 ZNF277 NUP188 POTEA CTPS1 SNRNP200 MTDH	3.33e-06	824	190	23	int:RNF123
Interaction	ARRDC3 interactions	MAGI2 DDX50 HPGDS PI4KA ITCH NEDD4L UBE2O POLDIP2 TNFRSF1A CTNND1 SNRNP200	9.54e-06	224	190	11	int:ARRDC3
Interaction	SLU7 interactions	MAP1A CHD4 MTMR3 APC TSSC4 UBE2O MTMR4 AKAP9 SNRNP200	1.76e-05	156	190	9	int:SLU7
ToppCell	facs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l26\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	STARD13 GPR162 TIAM2 HPGDS POLN FYB2 PSTPIP2 UBA6	8.34e-07	170	194	8	4b1c84b35b7242a297ffdb9c23a6d982acf1bed5
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM7 VPS13C PRPF6 GOLIM4 PARG CLOCK ARHGAP5 SCAF11	1.08e-06	176	194	8	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B SPTA1 OBSCN PKHD1 GRID1 TEX11 MYOM2 OTOG	1.51e-06	184	194	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B SPTA1 OBSCN PKHD1 GRID1 TEX11 MYOM2 OTOG	1.51e-06	184	194	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B SPTA1 OBSCN PKHD1 GRID1 TEX11 MYOM2 OTOG	1.51e-06	184	194	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	MAGI2 NPAS2 SHROOM3 DPP10 NEDD4L CP ERN2 ILDR1	1.92e-06	190	194	8	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	MAP1A CCDC30 ANKUB1 ODAD4 GPR162 CFAP45 CP DNAI3	1.92e-06	190	194	8	a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	GTF3C3 ZFP69B G2E3 CLOCK GSPT1 USP8 AKAP9 SCAF11	2.16e-06	193	194	8	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	MAP1A CCDC30 ANKUB1 ODAD4 GPR162 CFAP45 DYNC2I1 DNAI3	2.42e-06	196	194	8	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 ANKUB1 MAGI2 SHROOM3 NEDD4L RFX7 ZHX2 MBD5	2.42e-06	196	194	8	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	HLA-G ZNF354C MAGI2 GOLIM4 NPAS2 COL6A3 RNF213 ZHX2	2.61e-06	198	194	8	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-4\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	MAP1A AEBP1 SYNJ2 SCG2 SCARA3 COL6A3 MXRA5 P3H3	2.81e-06	200	194	8	7642a14855589b0b3f68dbdc9e4d3fc7291854f7
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-4-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAP1A AEBP1 SYNJ2 SCG2 SCARA3 COL6A3 MXRA5 P3H3	2.81e-06	200	194	8	444c72334df421375ae6fc69b0adfd4950d49a43
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-4\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	MAP1A AEBP1 SYNJ2 SCG2 SCARA3 COL6A3 MXRA5 P3H3	2.81e-06	200	194	8	5826c17da67bdaba3a828792279004218d8260c8
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HPGDS SLAMF9 SASH1 CP CBR3 ADAM22 UBE2O	7.81e-06	164	194	7	758e85e2f5e7236b345e16c78344d5e0bf17d8dc
ToppCell	Adult-Epithelial-club_cell-D122\|Adult / Lineage, Cell type, age group and donor	MAGI2 SHROOM3 NEDD4L CP ATP13A5 ERN2 ILDR1	1.33e-05	178	194	7	35a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OBSCN RIPOR3 MAGI2 AEBP1 ZFP69B MXRA5 GRID1	1.38e-05	179	194	7	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	droplet-Marrow-nan-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C PTPRO PLXDC1 YTHDC2 USP8 PDLIM1 SCAF11	1.54e-05	182	194	7	bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM7 ACSS1 GPR162 ST14 AEBP1 PYGB ILDR1	1.59e-05	183	194	7	f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM7 ACSS1 GPR162 ST14 AEBP1 PYGB ILDR1	1.65e-05	184	194	7	8939b6d795992775df0ff58ed1ec9d421a00bcc4
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	MAGI2 NPAS2 SHROOM3 DPP10 NEDD4L CP ERN2	1.83e-05	187	194	7	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	MAP1A ANKUB1 ODAD4 GPR162 CFAP45 CP DNAI3	1.83e-05	187	194	7	2b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	KIF3B AEBP1 ZSCAN2 CHD6 MXRA5 ITCH ZFTA	1.89e-05	188	194	7	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CCDC30 ANKUB1 ODAD4 CFAP45 FYB2 CP DNAI3	1.96e-05	189	194	7	dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell	droplet-Heart-HEART-1m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THNSL1 ACSS1 TRUB1 HPGDS SLAMF9 MBD5	1.99e-05	127	194	6	983489a69d3b1f1fe21110a862ac1dba53e9d31c
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ANKUB1 FAT2 COL6A3 CRYBG2 PSTPIP2	2.04e-05	76	194	5	efbbbf91bca35720d8ecddb076f2c9f4de25e44d
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ANKUB1 FAT2 COL6A3 CRYBG2 PSTPIP2	2.04e-05	76	194	5	254d18bece2676faa4bbeb8d48b1d327ab3c2215
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C GOLIM4 PARG LARP1B ARHGAP5 SCAF11 MTDH	2.10e-05	191	194	7	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MAP1A ANKUB1 ODAD4 GPR162 CFAP45 CP DNAI3	2.10e-05	191	194	7	dad675251e129254955eac179c84a641a4864586
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MAP1A ANKUB1 ODAD4 GPR162 CFAP45 CP DNAI3	2.10e-05	191	194	7	6d2cf41ee946137c039ddcc13593fc3f670afbba
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C GOLIM4 PARG LARP1B ARHGAP5 SCAF11 MTDH	2.10e-05	191	194	7	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C GOLIM4 PARG LARP1B ARHGAP5 SCAF11 MTDH	2.10e-05	191	194	7	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM7 GPR162 ST14 AEBP1 PYGB SLC4A3 ILDR1	2.24e-05	193	194	7	b397c14ac1e34c6be3f25d4417d200bc518d3048
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM7 GPR162 ST14 AEBP1 PYGB SLC4A3 ILDR1	2.24e-05	193	194	7	241a60d1f0d5832638fb3e1e4b7afa7387ea3c75
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ANKUB1 FGD3 SHROOM3 IYD PSTPIP2 PEX5L	2.28e-05	130	194	6	0a6b87635e650df431a88f2e6396abead84d901d
ToppCell	10x3'2.3-week_17-19-Hematopoietic-erythroid-late_erythroid\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SPTA1 RIPOR3 NEDD4L HECTD4 GSPT1 UBE2O DCAF11	2.32e-05	194	194	7	23b06707d21306b4483d64cb350b86aef352ce38
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A CCDC30 ANKUB1 ODAD4 CFAP45 DYNC2I1 DNAI3	2.40e-05	195	194	7	d211a836cf711fdb91b10d512f09d462be937cc5
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC30 ANKUB1 ODAD4 CFAP45 FYB2 CP DNAI3	2.40e-05	195	194	7	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A CCDC30 ANKUB1 ODAD4 GPR162 CFAP45 CP	2.48e-05	196	194	7	1386003f5d885f0ea080934f7e05fe05f142a3d5
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A CCDC30 ANKUB1 ODAD4 CFAP45 DYNC2I1 AKAP9	2.56e-05	197	194	7	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A CCDC30 ANKUB1 ODAD4 CFAP45 DYNC2I1 AKAP9	2.56e-05	197	194	7	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC30 ANKUB1 ODAD4 FYB2 DYNC2I1 DNAI3 AKAP9	2.56e-05	197	194	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A CCDC30 ANKUB1 ODAD4 CFAP45 DYNC2I1 AKAP9	2.56e-05	197	194	7	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A CCDC30 ANKUB1 ODAD4 CFAP45 DYNC2I1 AKAP9	2.56e-05	197	194	7	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	VPS13C ODAD4 SHROOM3 HIPK2 DYNC2I1 AKAP9 SCAF11	2.64e-05	198	194	7	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	(1)_T_cell-(16)_Tfh\|(1)_T_cell / shred on Cell_type and subtype	MTHFD2 FRMD4B TCF7 HIPK2 GPRIN3 ARHGAP5 METTL8	2.82e-05	200	194	7	3b28137e8e69b98fde9f6ab8320cb4d1c3543ef9
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DYNC2I1 CP ERN2 GSPT1 AKAP9 PDLIM1 CTNND1	2.82e-05	200	194	7	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	Club_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	NPAS2 SHROOM3 NEDD4L IYD CP ATP13A5	7.02e-05	159	194	6	a7bcff268b1962a561fd2848e01ae16565bce895
ToppCell	facs-Trachea-18m-Hematologic-myeloid-granulocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	STARD13 GPR162 TIAM2 HPGDS POLN FYB2	7.53e-05	161	194	6	d1f2e5245c7c247b684f48f9f877e149a3ee7c06
ToppCell	droplet-Lung-nan-18m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCXD1 GPR162 CRYBG2 PKD1L3 ILDR1 METTL8	8.06e-05	163	194	6	5efecdd8a069a822bc9d35b407092925a865e629
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCXD1 GPR162 CRYBG2 PKD1L3 ILDR1 METTL8	8.06e-05	163	194	6	0d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLCXD1 GPR162 CRYBG2 PKD1L3 ILDR1 METTL8	8.33e-05	164	194	6	b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLCXD1 GPR162 CRYBG2 PKD1L3 ILDR1 METTL8	8.33e-05	164	194	6	a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMD4B HPGDS SLAMF9 SASH1 CP CBR3	8.91e-05	166	194	6	b3d9b61847c6c96b8cb28b8a6aeda52f43c706ab
ToppCell	facs-Trachea-nan-18m-Myeloid-granulocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR162 TIAM2 HPGDS POLN FYB2 PSTPIP2	8.91e-05	166	194	6	7f8b4cf63c3e292ae421f111edaa4572717f4db1
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCDC30 SPTA1 TCF7 GEMIN5 CP YTHDC2	9.51e-05	168	194	6	9e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF354C FAT2 FGD3 DNAI3 ZNF419 CDK5RAP2	9.83e-05	169	194	6	8caf7996796a2e2716e3855de855c903d6126bf2
ToppCell	facs-Heart-LV-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AEBP1 NPAS2 COL6A3 P3H3 DYNC2I1 UBE2O	9.83e-05	169	194	6	849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT2 PKHD1 FYB2 MXRA5 NEDD4L ADAM22	1.02e-04	170	194	6	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FRMD4B NUP153 TCF7 RANBP6 GPRIN3 ARHGAP5	1.02e-04	170	194	6	adb625124832b0786a590e8f75b61e7263a1e0d4
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN GPR162 FYB2 SLAMF9 PLXDC1 ARHGAP5	1.05e-04	171	194	6	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	JMY TCF7 RNF213 GPRIN3 YTHDC2 AKAP9	1.05e-04	171	194	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	normal_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	PNMA1 QSOX2 COL6A3 GRWD1 CBR3 SLC4A2	1.08e-04	172	194	6	0657c736f3c52d25cf7f652eac005ddcde9232ef
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DCHS2 FYB2 NPAS2 CP ERN2 ILDR1	1.12e-04	173	194	6	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF1A GPR162 MAGI2 SCG2 PEX5L SLC4A3	1.19e-04	175	194	6	8362a46f5804333baa84cd56d450bc147f372a7e
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF1A GPR162 MAGI2 SCG2 PEX5L SLC4A3	1.19e-04	175	194	6	8b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN9 OBSCN FYB2 SLAMF9 PLXDC1 ARHGAP5	1.23e-04	176	194	6	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN9 OBSCN FYB2 SLAMF9 PLXDC1 ARHGAP5	1.23e-04	176	194	6	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPB41L4A PYGB SCARA3 SLC4A3 ADAM22 UBA6	1.27e-04	177	194	6	14fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FYB2 NPAS2 NEDD4L CP ERN2 ILDR1	1.27e-04	177	194	6	779ba86f53650772755b52460be03f18bb204e55
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FYB2 NPAS2 NEDD4L CP ERN2 ILDR1	1.27e-04	177	194	6	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	KIF1A JMY MTMR3 HIPK2 GRID1 ADAM22	1.27e-04	177	194	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|390C / Donor, Lineage, Cell class and subclass (all cells)	DCHS2 MAGI2 CP ATP13A5 ERN2 ILDR1	1.31e-04	178	194	6	fce60ce6b662f1bdaa3b4da43800c6c22fe89533
ToppCell	390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	DCHS2 MAGI2 CP ATP13A5 ERN2 ILDR1	1.31e-04	178	194	6	b19c906e067b07eadfd68934d9330b447e24c708
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	DCHS2 FYB2 NPAS2 CP ERN2 ILDR1	1.35e-04	179	194	6	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAPN9 PLCXD1 ST14 SHROOM3 NEDD4L ERN2	1.35e-04	179	194	6	c833ded1f9e87be2ba2037820d92a389560b711c
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MTHFD2 AEBP1 PI4KA CBR3 UBA6 ZFTA	1.35e-04	179	194	6	ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI2 SHROOM3 DPP10 NEDD4L CP ERN2	1.39e-04	180	194	6	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 RIPOR3 PXYLP1 SCARA3 NPAS2 SASH1	1.39e-04	180	194	6	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSS1 PKHD1 COL6A3 TCF7 DNAI3 CLOCK	1.43e-04	181	194	6	41969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSS1 PKHD1 COL6A3 TCF7 DNAI3 CLOCK	1.43e-04	181	194	6	3f50e61dc2a52d71a5801584617607e6246adcf2
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MAP1A ANKUB1 ODAD4 GPR162 CFAP45 DNAI3	1.47e-04	182	194	6	975f6275777fc578eba528e50f69891c66ec44ad
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MAP1A ANKUB1 ODAD4 GPR162 CFAP45 DNAI3	1.47e-04	182	194	6	f8c28fa76751062c4cfba0db8af1b377f947f739
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 CCDC30 ST14 PKHD1 IYD ILDR1	1.52e-04	183	194	6	2df1611c8acccb2a6f233d3d68bd9df2381a7278
ToppCell	COVID-19_Mild-gd_T\|COVID-19_Mild / Disease condition and Cell class	HLA-G EPB41L4A ITCH RNF213 FAM53B MYOM2	1.52e-04	183	194	6	f593a89b0aa8fffdfa403769916facfd30358521
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	CAPN9 MYO7B PYGB NPAS2 ERN2 CEMIP	1.52e-04	183	194	6	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 CCDC30 ST14 PKHD1 IYD ILDR1	1.56e-04	184	194	6	6388c47b7f1d8203e3069eba0e74107256dcae51
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C CHD4 PARG APC USP8 SCAF11	1.56e-04	184	194	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	droplet-Heart-4Chambers-18m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 CCDC30 ST14 PKHD1 IYD ILDR1	1.56e-04	184	194	6	d83ae1dc64aa1b27d3b524c137567418cc0ff8c6
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|368C / Donor, Lineage, Cell class and subclass (all cells)	FANCF PXYLP1 ZHX2 CLOCK MYOM2 METTL8	1.56e-04	184	194	6	d48807f9da48bdd015a54c606d2e2a311f181396
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPTA1 RIPOR3 QSOX2 HECTD4 UBE2O DCAF11	1.61e-04	185	194	6	c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PLCXD1 SYCE2 NPAS2 MYO19 YTHDC2 MBD5	1.61e-04	185	194	6	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PLCXD1 SYCE2 NPAS2 MYO19 YTHDC2 MBD5	1.61e-04	185	194	6	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	Immune-enucleated_erythrocyte\|World / Lineage, Cell type, age group and donor	SPTA1 RIPOR3 QSOX2 HECTD4 UBE2O DCAF11	1.66e-04	186	194	6	f9d5ec5cc8fd6e63bf25abe390307ec8a4a2d5a3
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC30 RIPOR3 MAGI2 PKHD1 SASH1 ZHX2	1.66e-04	186	194	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	GOLIM4 CASP8AP2 IYD APC USP8 SCAF11	1.66e-04	186	194	6	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD4 LANCL3 ARHGAP5 AKAP9 SCAF11 MTDH	1.71e-04	187	194	6	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	Ciliated_cells-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	MAP1A ANKUB1 CFAP45 FYB2 CP DNAI3	1.71e-04	187	194	6	6fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR3 MAGI2 PKHD1 SASH1 HIPK2 ZHX2	1.71e-04	187	194	6	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OLAH MFSD6 MAGI2 PTPRO CFAP45 GOLIM4	1.71e-04	187	194	6	24c2a3962da364e46e98abeab5f8234376fa26bb
Drug	Tacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; HL60; HT_HG-U133A	CHD4 NCAPH2 ST14 KIF3B GOLIM4 MYO19 TSSC4 ERN2 FAM53B PRKCSH PPP6R3	1.12e-06	200	192	11	1278_DN
Drug	uracil	UIMC1 SPTA1 TRUB1 NT5C FANCF SCG2 PYGB POLN SCARA3 NEDD4L APC ENDOV	3.25e-06	269	192	12	CID000001174
Drug	Telenzepine dihydrochloride [147416-96-4]; Down 200; 9uM; HL60; HT_HG-U133A	PRPF6 NCAPH2 FRMD4B KIF3B YTHDC2 ZHX2 AKAP9 ZNF277 FAM53B PRKCSH	6.77e-06	196	192	10	2388_DN
Drug	1,1-dimethylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A	VPS13C NCAPH2 FANCF SYNJ2 MOCS2 CRYBG2 TSSC4 ERN2 CERT1 ADAM22	8.09e-06	200	192	10	1_DN
Disease	primary ovarian insufficiency (implicated_via_orthology)	USP17L7 FANCF USP17L4 USP17L2 USP17L8	1.13e-05	46	189	5	DOID:5426 (implicated_via_orthology)
Disease	congenital heart disease (implicated_via_orthology)	USP17L7 CHD6 USP17L4 USP17L2 USP17L8	8.24e-05	69	189	5	DOID:1682 (implicated_via_orthology)
Disease	anemia (implicated_via_orthology)	APC SLC4A3 SLC4A2	1.11e-04	15	189	3	DOID:2355 (implicated_via_orthology)
Disease	Seasonal Affective Disorder	PER3 NPAS2 CLOCK	1.36e-04	16	189	3	C0085159
Disease	Choledochal Cyst, Type I	PKHD1 SLC4A2	4.03e-04	5	189	2	C0009439
Disease	Choledochal Cyst, Type II	PKHD1 SLC4A2	4.03e-04	5	189	2	C1257796
Disease	Choledochal Cyst, Type III	PKHD1 SLC4A2	4.03e-04	5	189	2	C1257797
Disease	Choledochal Cyst, Type IV	PKHD1 SLC4A2	4.03e-04	5	189	2	C1257798
Disease	Choledochal Cyst, Type V	PKHD1 SLC4A2	4.03e-04	5	189	2	C1257799
Disease	response to trauma exposure, post-traumatic stress disorder symptom measurement	GPRIN3 GRID1	4.03e-04	5	189	2	EFO_0008483, EFO_0008535
Disease	Choledochal Cyst	PKHD1 SLC4A2	4.03e-04	5	189	2	C0008340
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	PLRG1 ITCH HECTD4 PKD1L3	4.62e-04	56	189	4	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	Charcot-Marie-Tooth disease (implicated_via_orthology)	MTMR3 FGD3 MTMR4	4.74e-04	24	189	3	DOID:10595 (implicated_via_orthology)
Disease	blood osmolality measurement	KATNAL1 PKHD1 NEDD4L CEMIP	5.28e-04	58	189	4	EFO_0007967
Disease	neutropenia, response to metamizole, Drug-induced agranulocytosis	STARD13 PTPRO	6.02e-04	6	189	2	EFO_0010971, HP_0012235, MONDO_0001475
Disease	Child Development Disorders, Specific	KIF1A CHD4 TBCD	8.36e-04	29	189	3	C0085997
Disease	Child Development Deviations	KIF1A CHD4 TBCD	8.36e-04	29	189	3	C0085996
Disease	Epileptic encephalopathy	MAGI2 DENND5A NEDD4L	9.24e-04	30	189	3	C0543888
Disease	Developmental Disabilities	KIF1A CHD4 TBCD	9.24e-04	30	189	3	C0008073
Disease	Breast Cancer, Familial	PPM1D RECQL CHEK2	9.24e-04	30	189	3	C0346153
Disease	cerebellar ataxia (implicated_via_orthology)	VPS13C GEMIN5	1.11e-03	8	189	2	DOID:0050753 (implicated_via_orthology)
Disease	response to vitamin	GPR162 P3H3	1.11e-03	8	189	2	GO_0033273
Disease	centronuclear myopathy X-linked (implicated_via_orthology)	MTMR3 MTMR4	1.43e-03	9	189	2	DOID:0111225 (implicated_via_orthology)
Disease	Autosomal Recessive Polycystic Kidney Disease	PKHD1 SLC4A2	1.43e-03	9	189	2	C0085548
Disease	coronary artery disease	KIF1A TRPM7 CCDC30 EPB41L4A PTPRO PKHD1 DENND5A TBCD COL6A3 SHROOM3 DPP10 HECTD4 RNF213 PKD1L3 CERT1 CLOCK SCAF11	1.82e-03	1194	189	17	EFO_0001645
Disease	Colorectal Carcinoma	TRPM7 OBSCN NT5C CCDC62 PKHD1 APC GRID1 PEX5L AKAP9 CHEK2 SNRNP200 MTDH	1.99e-03	702	189	12	C0009402
Disease	uric acid measurement	TRPM7 PYGB QSOX2 NPAS2 IPPK SHROOM3 HECTD4 SLC5A9 CEMIP FAM53B ILDR1	2.02e-03	610	189	11	EFO_0004761
Disease	autosomal recessive polycystic kidney disease (biomarker_via_orthology)	PKHD1 SLC4A2	2.16e-03	11	189	2	DOID:0110861 (biomarker_via_orthology)
Disease	renal cell carcinoma	MYO7B SASH1 PRKCSH	2.47e-03	42	189	3	EFO_0000681
Disease	fibrinogen measurement, tissue plasminogen activator measurement	PLRG1 HECTD4 PKD1L3	3.01e-03	45	189	3	EFO_0004623, EFO_0004791
Disease	fibrinogen measurement, plasminogen activator inhibitor 1 measurement	PLRG1 HECTD4 PKD1L3	3.01e-03	45	189	3	EFO_0004623, EFO_0004792
Disease	Primary biliary cirrhosis	SLC4A2 TNFRSF1A TNPO3	3.41e-03	47	189	3	C0008312
Disease	age at menopause	UIMC1 CCDC30 ZNF483 CHD6 GEMIN5 GSPT1 TNPO3	3.45e-03	302	189	7	EFO_0004704
Disease	Parkinson's disease (implicated_via_orthology)	VPS13C SYNJ2 HIPK2 ATP13A5 LRRK1	3.48e-03	157	189	5	DOID:14330 (implicated_via_orthology)
Disease	quinate measurement	NOX5 GRID1	4.06e-03	15	189	2	EFO_0021167
Disease	cryptococcosis	HLA-G JMY	4.06e-03	15	189	2	EFO_0007229
Disease	aspartate aminotransferase to alanine aminotransferase ratio	EPPK1 NEDD4L ADAM22 USP8 CHEK2 CDK5RAP2	4.53e-03	239	189	6	EFO_0010934
Disease	cystatin C measurement	ACSS1 PKHD1 PYGB SHROOM3 PPM1D HECTD4 CEMIP ILDR1	4.55e-03	402	189	8	EFO_0004617
Disease	cystatin-F measurement	ACSS1 KIF3B	4.62e-03	16	189	2	EFO_0008104
Disease	plasminogen activator inhibitor 1 measurement	FRMD4B RFX7 MYOM2	5.05e-03	54	189	3	EFO_0004792
Disease	response to radiation, Urinary retention	CAMTA1 COL6A3	5.21e-03	17	189	2	GO_0009314, HP_0000016
Disease	hippocampal atrophy	MAGI2 CHD6 METTL8	5.59e-03	56	189	3	EFO_0005039
Disease	Tourette syndrome, schizophrenia	MYO19 ENTHD1	5.84e-03	18	189	2	EFO_0004895, MONDO_0005090
Disease	Mental Depression	PER3 NPAS2 GRID1 PEX5L CLOCK TNFRSF1A	6.07e-03	254	189	6	C0011570

Protein segments in the cluster

Peptide	Gene	Start	Entry
KTWLETEALPHRQDI	ZNF354C	86	Q86Y25
EDVEEETERWGKPHV	SLC4A2	351	P04920
VEEETERWGKPHVAS	SLC4A3	351	P48751
DQHVRKSPESVALIW	ACSS1	116	Q9NUB1
HSIQQVSEPWLEERK	AKAP9	2971	Q99996
PVSKKWEESLVADRH	ATP13A5	101	Q4VNC0
SLPKERHRWNTNEEI	CAMTA1	66	Q9Y6Y1
ETPTLSDEKQWHDVS	CCDC62	451	Q6P9F0
PHESELPREWENNKE	AEBP1	881	Q8IUX7
WSERIPDTKHISDIC	ADAM22	811	Q9P0K1
TTEEALRHPWLQDED	CHEK2	476	O96017
DIWDLLEKTHEPAQS	DNAI3	741	Q8IWG1
QWENTPLKAERHRTE	CASP8AP2	456	Q9UKL3
FRPIWVTLDTEDHKA	CEMIP	1331	Q8WUJ3
LHDPEARWINDTDVV	DPP10	81	Q8N608
KHEATREAWEEKPIN	CDK5RAP2	886	Q96SN8
WKDVPVEQVTHADRE	POLN	661	Q7Z5Q5
HKRTPSEAERWLEEV	NUMBL	406	Q9Y6R0
PHIDSSVIDSDEKWL	MTF2	136	Q9Y483
KDTVRGQEETPSWEH	NT5C	146	Q8TCD5
GTLDKVREEWQSEHI	PSTPIP2	196	Q9H939
EKPHKEENSEIVVWR	QSOX2	301	Q6ZRP7
KDARSPVADWSELAH	IPPK	221	Q9H8X2
APEHREQEWIEAKEL	P3H3	676	Q8IVL6
SAPEQKDTIWLHIRS	NOX5	496	Q96PH1
EPLEEFTSRHSLEWK	NPAS2	246	Q99743
IEEQSQSEKVRLHWP	CERT1	336	Q9Y5P4
SPQREWEKELHHLQE	CP	746	P00450
PEYWEEETRNTKAHA	HLA-G	81	P17693
PWLELSDVHRETTEN	POLDIP2	226	Q9Y2S7
DAEIKVREATSNDPW	ENTHD1	16	Q8IYW4
GTESQDVPWEELHNR	FANCF	296	Q9NPI8
WRLKTPDDHEAETGI	HIPK2	446	Q9H2X6
LHKDRWPEVSPEDTQ	MAP1A	1181	P78559
WTSKVHESVIGRNPE	MAGI2	11	Q86UL8
EETLESDWVAVRPHV	JMY	6	Q8N9B5
HQITQWDLAVERDPE	GRWD1	376	Q9BQ67
HKWSSSDDIRVLPAQ	GPR162	431	Q16538
AWAQHTDPSEKSEDV	LRRK1	1171	Q38SD2
PASWESHKIAERIEQ	MYO19	156	Q96H55
PEREAKEQHQKLWEE	PRKCSH	186	P14314
SREKLWDSELHPEEK	ERN2	406	Q76MJ5
DHRIEQADWPEIKST	HPGDS	31	O60760
TEEIETREVWTQHPG	DYNC2I1	546	Q8WVS4
PEEFERIKWASHVLT	CFAP45	106	Q9UL16
LPEKDSSLWHREAVT	FAM53B	71	Q14153
RREEEKWEAQSEGHP	PER3	901	P56645
EDDTATEETHPVSWK	PLRG1	491	O43660
HSDNEPVIKRTWSSE	FAT2	4156	Q9NYQ8
EQWETKHQRTERKIP	PARG	426	Q86W56
KELLWSSEHRSQPEL	PEX5L	206	Q8IYB4
VRDVSWHPFEEKIVS	DCAF11	486	Q8TEB1
SEEDKERQPQSWRAH	ILDR1	481	Q86SU0
DAVEEWLEENVHPSL	HEXD	441	Q8WVB3
KFLVTWHTIDADAPE	PI4KA	1591	P42356
HLKPSDRELVWQSVD	LANCL3	251	Q6ZV70
KWDSHFRESVEKTIP	IMMT	66	Q16891
DPEERLDSGHVWKLQ	FGD3	661	Q5JSP0
SLEEDPWPRVNSKDH	PPM1D	421	O15297
STQEQSHPGEEWVKE	NOL8	811	Q76FK4
WAAGKTVETVHPVRD	HECTD4	631	Q9Y4D8
TSAIPEEEIDWIEKH	MFSD6	46	Q6ZSS7
EDTLTEISEWLERHP	PLCXD1	131	Q9NUJ7
SPEESWEHKEEISEA	GSPT1	16	P15170
VDKKETEVTRWVPDH	MTMR4	1101	Q9NYA4
GEWIEELTEKPQHVS	PTPRO	426	Q16827
VVIEKREHSPSWTFE	DCHS2	1071	Q6V1P9
HDPSPEEQDREWKEQ	GOLIM4	361	O00461
SDPEAHVVWRKDGVQ	OBSCN	2671	Q5VST9
DHVEKRTTWDRPEPL	ITCH	346	Q96J02
ESSEQRLFWHEDSKP	FRMD4B	1016	Q9Y2L6
GIHIPEKDASWELEE	G2E3	206	Q7L622
KHVERPASDSWQKLE	CHD6	436	Q8TD26
GHIPTEEQVSWLSKE	CS	126	O75390
TENSAKLHWERAEPP	COL6A3	3001	P12111
HVVLWEPDEDRASQI	CRYBG2	1641	Q8N1P7
EPDEDRASQIWTIHV	CRYBG2	1646	Q8N1P7
VPTTESERLQAEWHD	DDX50	636	Q9BQ39
LQHEDESVPEATEKW	CCDC30	671	Q5VVM6
EKNEVVPEENWHTRA	DENND5A	1181	Q6IQ26
EVDEGAWETKISHRE	MTDH	186	Q86UE4
LTSWPGKLVREDDVH	MBD5	1396	Q9P267
VEDTKNEVHEREGWP	CBR3	176	O75828
KRNARWSTHTPLDEE	GBF1	21	Q92538
KDSHWVFVNEEISDP	GRID1	251	Q9ULK0
AHVVDRDTEAWQRDP	ENDOV	26	Q8N8Q3
NWKVTVDPAETSVEH	FAM217A	271	Q8IXS0
ESEIKEVPSRAWQDA	GPRIN3	306	Q6ZVF9
LTPDALEEDAIHKWE	CAPN9	336	O14815
EESVDPDYWEKLLRH	CHD4	1306	Q14839
SRSPDIQAKEELWKH	EPB41L4A	541	Q9HCS5
TFDPWLEHTNEVLEE	PNMA1	176	Q8ND90
TEAHKWRPDSRESQE	PPP1R18	236	Q6NYC8
TRNPEKLKESHWEEN	SCAF11	1036	Q99590
KAWHRIPKDDELSEE	OLAH	136	Q9NV23
SEWIHGIQRKTDEET	SCARA3	231	Q6AZY7
PEEKARESSWDHVKT	METTL8	121	Q9H825
EPNEDCKPRHIEWES	CTNND1	511	O60716
PRSDSLILDHQWELE	KIF1A	1366	Q12756
DLDSEPWIEVKKRHQ	LARP1B	366	Q659C4
VDKQDTEMTRWLPDH	MTMR3	1106	Q13615
VARSEHKVWSPLVTE	PDLIM1	81	O00151
RPWVDEDLKDSSDLH	IYD	41	Q6PHW0
IHSVDNLDDITWPSE	POTEA	411	Q6S8J7
PESFLDDKQEVHTWR	OTOG	1061	Q6ZRI0
RNPSIHWDDIADLEE	KATNAL1	201	Q9BW62
QLWKEIETRHPGLAD	MOCS2	36	O96033
DDWSKDVLPELQTHD	STARD13	501	Q9Y3M8
RKEPLIVAHAEAASW	CARS2	61	Q9HA77
SQHRFWKPSEVEEEV	UVSSA	526	Q2YD98
AEEKSSIHDARSWVP	STK40	386	Q8N2I9
QEAWKRSLATVHPDS	SFXN4	86	Q6P4A7
DLDVDTKVRHTWSPG	SYNJ2	826	O15056
EVEEWVASGNKRPHL	MTHFD2	56	P13995
PTDRHIWITAAKLEE	PRPF6	461	O94906
KIDDEVHAAPWNTTR	TAF1L	941	Q8IZX4
EPEKVVKQWDHSEDE	ODAD4	531	Q96NG3
EDPSFVISQHIRKSW	FYB2	211	Q5VWT5
DRETWHKLSELEPGT	EPPK1	181	P58107
SWLESKRHTEPVEDI	PKD1L3	371	Q7Z443
ESHLPERDSLSEEDW	SCG2	96	P13521
TSQEEPVRYHEAWQK	CTPS1	346	P17812
AKWAHAAREDSLPEE	SHROOM3	1431	Q8TF72
EQKLTSIEEEPLWRH	SLC5A9	646	Q2M3M2
ELWQDREKPSEHSVR	PXYLP1	406	Q8TE99
DAVDWRPHDKIVLSS	PKHD1	2886	P08F94
LEKTPWDETDHIDKI	ARHGAP5	381	Q13017
LGESKEHPRWEENCE	SYCE2	21	Q6PIF2
SWLPLHEDKEEAIQT	RANBP6	1006	O60518
SNWEKIEQFHSRPDD	SULT1B1	26	O43704
VVGDELKTPIRSWHD	SEC23A	301	Q15436
HLNPSDTEEWVRLAE	GTF3C3	211	Q9Y5Q9
NERWARPKHIIEDEI	APC	1046	P25054
ELTEWALKQGARPHE	ANKUB1	206	A6NFN9
EPNEEFTSRHSLEWK	CLOCK	271	O15516
EVAEQWLRPAEEDHL	NCAPH2	411	Q6IBW4
ANLEPEDKTTVHRKW	RECQL	346	P46063
VSKNHTERDPVLWSL	RNF213	2671	Q63HN8
EEKPDVNADIVHWLS	UBA6	366	A0AVT1
RPDEVVAEEAWQRHK	USP19	621	O94966
LDWETKPEIHDASDK	ZNF2	91	Q9BSG1
IQAWLQEHRPESSEE	ZSCAN2	106	Q7Z7L9
ERATEESTLDHWKFP	USP17L4	426	A6NCW7
WELIHTKSEIEGRPE	TIAM2	1416	Q8IVF5
QTWDEEEKAFIPTLH	RIPOR3	246	Q96MK2
DEEEDHWKLHPITRL	KIF3B	606	O15066
WQESRTEGEHSKEVI	TIPRL	91	O75663
WSEFSIPQHLVEEAE	ST14	156	Q9Y5Y6
HWSPRVKDLIVSGDE	GEMIN5	116	Q8TEQ6
RVEHTPDGVKWLDTQ	PYGB	206	P11216
WETDNGLVEDEHPKI	UBE2O	741	Q9C0C9
VAHPERWTKYSLEDV	TSSC4	156	Q9Y5U2
RLKHGVSWTPEEVEE	ZHX1	336	Q9UKY1
ETDDSDTWEPPRHVK	ZHX1	851	Q9UKY1
KPHDVISHEDGTLWR	NUP188	481	Q5SRE5
FISTRHVWPEDCEQK	THNSL1	231	Q8IYQ7
VDTWPRSHSLDDLQV	SASH1	831	O94885
ESVWELPHLETKTFE	TEX11	761	Q8IYF3
SSVPDHLKEQEDWTD	VPS13C	1911	Q709C8
PEHSDINDLEKSVWE	RFX7	711	Q2KHR2
ADLHEAETWIREKEP	SPTA1	906	P02549
PDEEVENIIWSSHKS	SLAMF9	46	Q96A28
DTSEVPRWPENKEDH	NUP153	71	P49790
EKHQESTTETNWPRE	TCF7	351	P36402
EHGKDPWIIESELSR	ZNF630	61	Q2M218
IWPVLSETLNKHRAD	TNPO3	641	Q9Y5L0
LEHGQEPWTRKEDLS	ZNF264	66	O43296
ELTITPDFQWDEKVH	SNRNP200	1201	O75643
KHGISWSPEEVEEAR	ZHX2	316	Q9Y6X8
KLDEWLHFTLEPEAA	YTHDC2	1106	Q9H6S0
HTSLLPDRKTWDQLE	ZNF277	381	Q9NRM2
HPKAATERVALWEDV	ZFP69B	21	Q9UJL9
KERDKELVSPHEWEQ	TEX13A	141	Q9BXU3
GEIRIWVKSQHPESS	ZNF483	106	Q8TF39
EEHALPEDKWTIDDI	TRUB1	286	Q8WWH5
ERATQESTLDHWKFP	USP17L7	426	P0C7H9
ERATEESTLDHWKFP	USP17L8	426	P0C7I0
RAWTRKEALPDHEDE	PHF8	441	Q9UPP1
EELQSWVREHNPESG	ZBED9	106	Q6R2W3
TPEVIEKSVRDLEHW	TEX33	226	O43247
VTIQNPKDHEAWETR	TBCD	136	Q9BTW9
DEKIRVSWAAAPHSI	WDR4	166	P57081
EPHSRELWVDVAEAN	PLXDC1	101	Q8IUK5
SKTHEITQLESWEEP	ZNF419	71	Q96HQ0
DIWEEKHIAFTPESQ	PPP6R3	621	Q5H9R7
WEDSAHKPQSLDTDD	TNFRSF1A	341	P19438
TASWIEAHLPDDSKD	USP8	231	P40818
TEDLWPEHSIKDSFQ	ZNF680	91	Q8NEM1
AEEREEPWDHTEKTE	UIMC1	176	Q96RL1
EEWSVEKHTEQSPTD	TRPM7	76	Q96QT4
EHGQEPWTRKEDLSQ	ZNF805	66	Q5CZA5
ERATQESTLDHWKFP	USP17L2	426	Q6R6M4
SPREKEVISNSWDAH	ZFTA	156	C9JLR9
ISQEEWGHQDPSKRA	ZNF263	226	O14978
LWKHSEKEPETNVAE	MXRA5	746	Q9NR99
VLVEDDEGKEHWIRA	MYO7B	36	Q6PIF6
TSVVVQWDRPKHEED	MYOM2	626	P54296
IDHNTKTTTWEDPRL	NEDD4L	516	Q96PU5