Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsteroid hormone binding

ATP1A1 ATP1A3

5.88e-057342GO:1990239
GeneOntologyMolecularFunctionP-type sodium transporter activity

ATP1A1 ATP1A3

1.26e-0410342GO:0008554
GeneOntologyMolecularFunctionP-type sodium:potassium-exchanging transporter activity

ATP1A1 ATP1A3

1.26e-0410342GO:0005391
GeneOntologyMolecularFunctionP-type potassium transmembrane transporter activity

ATP1A1 ATP1A3

1.53e-0411342GO:0008556
GeneOntologyMolecularFunctionsteroid binding

ATP1A1 ATP1A3 NR1H4

1.49e-03133343GO:0005496
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP1A1 ATP1A3

1.71e-0336342GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP1A1 ATP1A3

1.71e-0336342GO:0015662
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ANO5 ATP10B

3.41e-0351342GO:0140303
GeneOntologyMolecularFunctionserine-type endopeptidase activity

TLL1 PARL PRSS21

4.08e-03190343GO:0004252
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP1A1 ATP1A3

4.99e-0362342GO:0019829
GeneOntologyMolecularFunctionserine-type peptidase activity

TLL1 PARL PRSS21

5.19e-03207343GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

TLL1 PARL PRSS21

5.54e-03212343GO:0017171
GeneOntologyBiologicalProcessresponse to glycoside

ATP1A1 ATP1A3

2.47e-055332GO:1903416
GeneOntologyCellularComponentphotoreceptor inner segment membrane

ATP1A1 ATP1A3

1.45e-054332GO:0060342
GeneOntologyCellularComponentsodium:potassium-exchanging ATPase complex

ATP1A1 ATP1A3

1.58e-0412332GO:0005890
HumanPhenoRetinal vascular malformation

PIK3CA KRIT1

3.04e-054122HP:0007797
HumanPhenoFocal T2 hypointense brainstem lesion

PIK3CA KRIT1

3.04e-054122HP:0012749
HumanPhenoRetinal cavernous hemangioma

PIK3CA KRIT1

3.04e-054122HP:0011513
HumanPhenoCerebral cavernous malformation

PIK3CA KRIT1

5.07e-055122HP:0033522
HumanPhenoChoroidal hemangioma

PIK3CA KRIT1

5.07e-055122HP:0007872
HumanPhenoNeuroma

PIK3CA KRIT1

7.59e-056122HP:0030430
HumanPhenoAdrenal calcification

PIK3CA KRIT1

1.41e-048122HP:0010512
HumanPhenoAscites

HFE DOCK6 PIK3CA NR1H4

1.92e-04134124HP:0001541
HumanPhenoVestibular schwannoma

PIK3CA KRIT1

2.77e-0411122HP:0009588
HumanPhenoVenous malformation

PIK3CA KRIT1

2.77e-0411122HP:0012721
MousePhenoabnormal dorsal aorta morphology

RDH10 PIK3CA TLL1 KRIT1

8.52e-0681234MP:0004787
MousePhenoabnormal vascular development

RDH10 ANO5 HAS2 PIK3CA TLL1 KRIT1 PARL

1.81e-05542237MP:0000259
MousePhenoabnormal artery development

RDH10 PIK3CA TLL1 KRIT1

6.03e-05133234MP:0003410
MousePhenoincomplete embryo turning

RDH10 HAS2 KRIT1

1.59e-0465233MP:0001701
MousePhenoabnormal cardiovascular development

RDH10 ANO5 HAS2 PIK3CA TLL1 KRIT1 PARL

2.17e-04802237MP:0002925
MousePhenoabnormal angiogenesis

RDH10 ANO5 PIK3CA TLL1 KRIT1

2.94e-04372235MP:0000260
MousePhenoabnormal blood vessel morphology

RDH10 ANO5 HAS2 PIK3CA NR1H4 TLL1 GSR KRIT1 PARL

3.21e-041472239MP:0001614
Domain-

ATP10B ATP1A1 ATP1A3

2.19e-05323232.70.150.10
Domain-

ATP10B ATP1A1 ATP1A3

2.19e-05323233.40.1110.10
DomainATPase_P-typ_cyto_domN

ATP10B ATP1A1 ATP1A3

2.88e-0535323IPR023299
DomainATPase_P-typ_P_site

ATP10B ATP1A1 ATP1A3

3.14e-0536323IPR018303
DomainP_typ_ATPase

ATP10B ATP1A1 ATP1A3

3.14e-0536323IPR001757
DomainATPASE_E1_E2

ATP10B ATP1A1 ATP1A3

3.14e-0536323PS00154
DomainATPase_P-typ_transduc_dom_A

ATP10B ATP1A1 ATP1A3

3.41e-0537323IPR008250
DomainE1-E2_ATPase

ATP10B ATP1A1 ATP1A3

3.41e-0537323PF00122
DomainP-type_ATPase_IIC

ATP1A1 ATP1A3

4.25e-056322IPR005775
DomainHAD-like_dom

ATP10B ATP1A1 ATP1A3

3.31e-0479323IPR023214
Domain-

ATP1A1 ATP1A3

3.36e-04163221.20.1110.10
DomainATPase_P-typ_TM_dom

ATP1A1 ATP1A3

3.36e-0416322IPR023298
DomainATPase_P-typ_cation-transptr_C

ATP1A1 ATP1A3

3.81e-0417322IPR006068
DomainCation_ATPase_C

ATP1A1 ATP1A3

3.81e-0417322PF00689
DomainCation_ATPase_N

ATP1A1 ATP1A3

4.28e-0418322PF00690
DomainCation_ATPase_N

ATP1A1 ATP1A3

4.28e-0418322SM00831
DomainATPase_P-typ_cation-transptr_N

ATP1A1 ATP1A3

4.78e-0419322IPR004014
DomainGlyco_trans_2-like

HAS2 UGCG

1.20e-0330322IPR001173
DomainGlycos_transf_2

HAS2 UGCG

1.20e-0330322PF00535
DomainARM-type_fold

USP34 NUP188 ECPAS PIK3CA

2.57e-03339324IPR016024
Domain-

HAS2 UGCG

8.47e-03813223.90.550.10
DomainNucleotide-diphossugar_trans

HAS2 UGCG

9.93e-0388322IPR029044
Pubmed

Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.

ATP1A1 ATP1A3

9.28e-07234221498719
Pubmed

Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.

ATP1A1 ATP1A3

9.28e-07234223761886
Pubmed

The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.

ATP1A1 ATP1A3

9.28e-0723423030810
Pubmed

All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.

ATP1A1 ATP1A3

9.28e-07234211546672
Pubmed

Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.

ATP1A1 ATP1A3

9.28e-07234224391932
Pubmed

Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression.

ATP1A1 ATP1A3

2.78e-0633428203495
Pubmed

Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.

ATP1A1 ATP1A3

2.78e-0633422822726
Pubmed

Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.

ATP1A1 ATP1A3

2.78e-06334230819023
Pubmed

Na,K-ATPase and the role of alpha isoforms in behavior.

ATP1A1 ATP1A3

2.78e-06334218044013
Pubmed

Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.

ATP1A1 ATP1A3

2.78e-06334226988030
Pubmed

Glycoprotein nonmetastatic melanoma protein B (GPNMB) promotes the progression of brain glioblastoma via Na+/K+-ATPase.

ATP1A1 ATP1A3

2.78e-06334227836549
Pubmed

Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.

ATP1A1 ATP1A3

2.78e-06334226373354
Pubmed

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.

ATP1A1 ATP1A3

2.78e-06334226911348
Pubmed

Differential expression of Na+/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells.

ATP1A1 ATP1A3

2.78e-06334217947306
Pubmed

Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase.

ATP1A1 ATP1A3

2.78e-06334225994790
Pubmed

Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders.

ATP1A1 ATP1A3

2.78e-06334219058785
Pubmed

Knockout of sodium pump α3 subunit gene (Atp1a3-/-) results in perinatal seizure and defective respiratory rhythm generation.

ATP1A1 ATP1A3

2.78e-06334228465228
Pubmed

Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.

ATP1A1 ATP1A3

5.56e-06434221731499
Pubmed

The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.

ATP1A1 ATP1A3

5.56e-06434212458206
Pubmed

Na,K-ATPase expression in the mouse cochlea is not dependent on the mineralocorticoid receptor.

ATP1A1 ATP1A3

5.56e-06434211591489
Pubmed

Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.

ATP1A1 ATP1A3

5.56e-06434219751721
Pubmed

Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.

ATP1A1 ATP1A3

5.56e-06434219376779
Pubmed

Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.

ATP1A1 ATP1A3

5.56e-06434221849490
Pubmed

Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.

ATP1A1 ATP1A3

5.56e-06434217446412
Pubmed

Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.

ATP1A1 ATP1A3

5.56e-06434217234593
Pubmed

Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism.

ATP1A1 ATP1A3

5.56e-0643422887455
Pubmed

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.

PIK3CA KRIT1

5.56e-06434233910229
Pubmed

Familial Cerebral Cavernous Malformations

PIK3CA KRIT1

5.56e-06434220301470
Pubmed

Multiple genes encode the human Na+,K+-ATPase catalytic subunit.

ATP1A1 ATP1A3

9.26e-0653423035563
Pubmed

The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.

ATP1A1 ATP1A3

1.39e-0563423036582
Pubmed

Transport and pharmacological properties of nine different human Na, K-ATPase isozymes.

ATP1A1 ATP1A3

1.39e-05634210636900
Pubmed

Differential involvement of Na(+),K(+)-ATPase isozymes in preimplantation development of the mouse.

ATP1A1 ATP1A3

1.94e-05734210837135
Pubmed

Expression and distribution of Na, K-ATPase isoforms in the human uterus.

ATP1A1 ATP1A3

1.94e-05734220065300
Pubmed

Molecular genetics of Na,K-ATPase.

ATP1A1 ATP1A3

1.94e-0573422158121
Pubmed

Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit.

ATP1A1 ATP1A3

2.59e-05834219683723
Pubmed

Genes encoding alpha and beta subunits of Na,K-ATPase are located on three different chromosomes in the mouse.

ATP1A1 ATP1A3

2.59e-0583422885848
Pubmed

Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice.

ATP1A1 ATP1A3

2.59e-05834223652595
Pubmed

Gene expression analysis of a panel of cell lines that differentially restrict HIV-1 CA mutants infection in a cyclophilin a-dependent manner.

TLL1 PRSS21

3.33e-05934224663101
Pubmed

The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.

ATP1A1 ATP1A3

3.33e-05934215253893
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 NUP188 MDN1 ATP1A1 ECPAS UTP25

3.68e-0565334622586326
Pubmed

Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach.

ATP1A1 ATP1A3 ECPAS

5.07e-057334323464991
Pubmed

Retinal pigment epithelial integrity is compromised in the developing albino mouse retina.

ATP1A1 ATP1A3

6.08e-051234227097562
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

HFE USP34 NUP188 MDN1 DOCK6 FASTKD1 UGCG

6.31e-05106134733845483
Pubmed

Chromosomal assignments of 17 structural genes and 11 related DNA fragments in rats (Rattus norvegicus) by Southern blot analysis of rat x mouse somatic cell hybrid clones.

ATP1A1 ATP1A3

8.38e-05143421572638
Pubmed

PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes.

ATP1A1 ATP1A3

1.25e-041734236230906
Pubmed

RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks.

ATP1A1 ATP1A3

1.57e-041934220861386
Pubmed

Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol.

ATP1A1 ATP1A3

1.74e-042034215648052
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

NUP188 PUS3 ATP1A3 CENPN PIK3CA GSR PARL

2.52e-04132734732694731
Pubmed

A protein interaction landscape of breast cancer.

ACOT8 NUP188 MDN1 ECPAS PIK3CA

3.56e-0463434534591612
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP1A1 ATP1A3

3.70e-042934215071553
Pubmed

Chromosomal localization of human Na+, K+-ATPase alpha- and beta-subunit genes.

ATP1A1 ATP1A3

3.97e-04303422842249
Pubmed

A genetic approach to Mammalian glycan function.

HAS2 UGCG

3.97e-043034212676797
Pubmed

Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues.

ATP1A1 ATP1A3

7.79e-044234215146195
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

ACOT8 MDN1 ECPAS DOCK6 FASTKD1

7.81e-0475434533060197
Pubmed

ZBTB20 is essential for cochlear maturation and hearing in mice.

ATP1A1 ATP1A3

9.75e-044734237279265
InteractionGPR182 interactions

EXOC1 MDN1 ATP1A3 NEK6 ECPAS FASTKD1 PARL

7.34e-06455337int:GPR182
InteractionGYPA interactions

EXOC1 TTC39A NEK6 ECPAS FASTKD1

8.84e-06174335int:GYPA
InteractionEDNRB interactions

EXOC1 ATP1A3 ECPAS

3.51e-0539333int:EDNRB
InteractionHLA-B interactions

NUP188 MDN1 ATP1A3 ECPAS FASTKD1

4.07e-05239335int:HLA-B
InteractionTNFSF13B interactions

USP34 EXOC1 NUP188 MDN1

4.14e-05119334int:TNFSF13B
InteractionSSR2 interactions

MDN1 ATP1A1 ATP1A3

5.79e-0546333int:SSR2
InteractionBSG interactions

EXOC1 MDN1 ATP1A1 ECPAS PIK3CA FASTKD1 PARL

6.00e-05631337int:BSG
InteractionGPR17 interactions

EXOC1 MDN1 ATP1A3 ECPAS FASTKD1

9.06e-05283335int:GPR17
InteractionIL3 interactions

PIK3CA IL3RA

1.16e-0410332int:IL3
InteractionGPR55 interactions

ATP1A3 ECPAS FASTKD1

1.78e-0467333int:GPR55
GeneFamilyATPase Na+/K+ transporting subunits

ATP1A1 ATP1A3

3.84e-0572521208
CoexpressionLINDGREN_BLADDER_CANCER_WITH_LOH_IN_CHR9Q

NUP188 NEK6 ECPAS UGCG

1.52e-05116344M8411
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

TDRD10 TTC39A IL3RA UGCG

5.95e-0615634419472ef1642c2ad333aa3ce3675a25c6ab1d4556
ToppCelldroplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A1 ATP1A3 GSR

7.07e-06163344f6c8db5963ee1f8e0c2996f1aeecd58c00e9b099
ToppCelldroplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A1 ATP1A3 GSR

7.25e-06164344ea2897942ad72fba900c7ab354d6a9e203bf0e4a
ToppCelldroplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A1 ATP1A3 GSR

8.16e-06169344c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCelldroplet-Lung-nan-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A1 ATP1A3 GSR

8.16e-06169344ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCelldroplet-Lung-nan-21m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A1 ATP1A3 GSR

8.75e-0617234451bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCelldroplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A1 ATP1A3 GSR

8.75e-06172344be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

TDRD10 DOCK6 IL3RA TLL1

1.29e-0519034407b675befcd1d0a9c90cb17b5d22323468325d51
ToppCellmoderate-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RDH10 ATP10B ATP1A1 GSR

1.52e-051983447ecce5e266bb08797088cc8f8309e0c7b48df5c9
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RDH10 ATP10B ATP1A1 TLL1

1.55e-05199344527aae1d9d37a50deefc01fc0c064a53673681bd
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RDH10 ATP10B ATP1A1 GSR

1.58e-05200344b68d212159b9d04866ba02ff55c35be247805eec
ToppCell5'-Airway_Nasal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RDH10 ATP10B ATP1A1 GSR

1.58e-05200344f6e967738b4f7b173d6e9977e305f77380dd6c8a
ToppCell5'-Airway_Nasal-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RDH10 ATP10B ATP1A1 GSR

1.58e-05200344358d71329921451c7f5a56f1db0f9989af2299dc
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Ndst4_(Subiculum)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ANO5 TTC39A CENPN

4.28e-0589343497771687b48c7e0fa87e31962feaafd8f248b98
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RDH10 HAS2 IL3RA

1.23e-04127343353484362448f27e8377447d0c26391b1da7acc5
ToppCellASK454-Epithelial-Type_2|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

HFE ANO5 PUS3

1.51e-04136343ff9a5e111993fdb3ac64c5ef269e3460ff994517
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HAS2 ATP1A3 GSR

1.82e-04145343ab0e254a8d01021619853a6c175f620ccef217d8
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HAS2 ATP1A3 GSR

1.82e-041453432beb4ea3838796c580076ab7769de877a3a0552c
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PUS3 MDN1 CENPN

1.98e-0414934365778f19599b4955c0a16f0121237656449431fb
ToppCelldroplet-Lung-nan-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A1 ATP1A3

2.14e-04153343f6ef14d949107c08cb3690e26ec91e194cb43518
ToppCelldroplet-Lung-nan-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A1 ATP1A3

2.14e-041533436dcab3d50ab50051955204dc4e4a64c1ca855bcd
ToppCell343B-Myeloid-Dendritic-pDC|343B / Donor, Lineage, Cell class and subclass (all cells)

IL3RA FASTKD1 UGCG

2.26e-04156343547e2debfc09c07c049a880dded5fda7dd53e156
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.30e-041573430ad242320ada7bcb9e29548d3050bf4fd3a07115
ToppCellfacs-Lung-Endomucin-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.30e-04157343fe4c9556806203e57522d1986754ebe5a20aa2de
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_3|367C / Donor, Lineage, Cell class and subclass (all cells)

NEK6 IL3RA UGCG

2.35e-041583430559cc032d0b518bb9e55aa3495f5573bd8e87dd
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TTC39A IL3RA UGCG

2.44e-0416034361f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellURO-Other|URO / Disease, Lineage and Cell Type

TTC39A IL3RA UGCG

2.44e-04160343b0923e6bacfaba8ca40aa5706bf270eea0938b0a
ToppCellURO-Other-RBC|URO / Disease, Lineage and Cell Type

TTC39A IL3RA UGCG

2.44e-04160343558f3b0719e2461a69e1b93b08e21675e8d07a5a
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TTC39A IL3RA UGCG

2.44e-0416034334b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCellfacs-Spleen-nan-3m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.48e-0416134345591addc765760db6029ac19e80573373d1d917
ToppCellfacs-Spleen-nan-3m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.48e-041613438741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCellfacs-Spleen-nan-3m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.48e-041613439cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCelldroplet-Spleen-nan-21m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TTC39A GSR

2.67e-04165343fbd84f211ad645c91b9f45a0815391606f3206ac
ToppCelldroplet-Spleen-nan-21m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TTC39A GSR

2.67e-041653436fbdfacb49e627712ac999d40ae22dcb390edd3e
ToppCelldroplet-Lung-nan-18m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.67e-04165343e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCelldroplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.67e-041653430fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCelldroplet-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.71e-04166343e841e62cb20235d6233f78f4155fb8c0ffb1ef1b
ToppCelldroplet-Lung-LUNG-1m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.71e-04166343dd5944101ef58a9a29aa3eb5c17690119572b8f1
ToppCell10x5'-Liver-Myeloid_Dendritic-pDC|Liver / Manually curated celltypes from each tissue

TTC39A IL3RA UGCG

2.71e-0416634324dfa9f3e0842f9ab8350bf6a52ae0d10f2a0c44
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.71e-041663438e5e8de51b4dacdadaa5a08279df30b5c7ed3628
ToppCelldroplet-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.71e-041663433ca3ddb663644f0e7f70f9b75833bb54cd9191d3
ToppCelldroplet-Spleen-nan-3m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TTC39A NEK6

2.71e-04166343c1f18de4a1a2b6cdc703e6d29d136e1134fcbdf3
ToppCelldroplet-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.71e-04166343f751cbd01d4978ded7755874ab60504f6291afd7
ToppCelldroplet-Spleen-nan-3m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TTC39A NEK6

2.71e-0416634394c30d6ca179d0cb02a5ed0093c5a2871e17ae50
ToppCelldroplet-Kidney-nan-24m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.76e-041673432ee1660be117e20f24557522345572d11cbee813
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

TTC39A IL3RA UGCG

2.76e-04167343bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCelldroplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TTC39A NEK6

2.76e-04167343f33cef917fa733adf6d5a9a9e989a4d9fd462a8f
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

TTC39A IL3RA UGCG

2.81e-04168343968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

TTC39A IL3RA UGCG

2.81e-04168343dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A3 GSR

2.81e-0416834300cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A1 GSR

2.81e-041683434b5be7c6662eceddf90a65015f12908278d1664e
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.81e-04168343f3b7a7df54988de77dcc7066e2fc1feb9c280b13
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A1 GSR

2.81e-04168343689c41f6e9f65381570991cc311cba49a57ec955
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

TTC39A IL3RA UGCG

2.81e-04168343cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A1 GSR

2.86e-04169343411556e93adcbb7e4d79b02f3dc72963ec8a0759
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

RDH10 HFE CENPN

2.86e-04169343625788d86f0ceebcf2653a251db1f1a9f9746d29
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A3 GSR

2.86e-0416934390c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCelldroplet-Lung-LUNG-30m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A1 GSR

2.86e-0416934339b1acfd099abb9de18c29c05c7a67709ea76775
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A3 GSR

2.86e-04169343b059304543876f514d5c7214f1f0a2da00f10a67
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A3 GSR

2.86e-04169343945f737984c4de70a4e9c214053b005358053dd5
ToppCelldroplet-Spleen-nan-3m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.86e-0416934391cfff1ad559cc327c6bb71c98aa29f0b3642568
ToppCelldroplet-Spleen-nan-3m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.86e-04169343972618e684321060c7af2429f853a6d639e8aae8
ToppCelldroplet-Spleen-nan-3m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.86e-041693438e5e513090e86ca29fb61dfd388014774c506914
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.91e-041703437cb7ad9ab064b6ea452545d145e5b1d4090cd4c1
ToppCelldroplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A3 GSR

2.91e-041703434d28dc9eb572f43809619f923978cd7494853d43
ToppCellsevere_influenza-pDC|World / disease group, cell group and cell class (v2)

TTC39A IL3RA UGCG

2.91e-04170343b9c08af83241666bbdbed9109cadcd088c0f647d
ToppCelldroplet-Spleen-nan-21m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.91e-0417034303cb4e508356f85372a588c8d1c6babf2a012683
ToppCell367C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ATP1A3 IL3RA UGCG

2.91e-04170343fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.91e-04170343db7cee7e518debb2cbe9eeae05d47e14b69cb8e3
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TLL1 FASTKD1

2.91e-041703438e774af244cfe787fa0ea2b6be0c3c2d00bfe4fc
ToppCellfacs-Heart-RV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAS2 ATP1A3 GEMIN8

2.91e-04170343d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCellNS-critical-d_0-4-Myeloid-Monocyte-derived_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HFE ANO5 ZNF57

2.91e-04170343adf73bdc049d508f8873c22539db2ca92052a97b
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TLL1 FASTKD1

2.91e-04170343f5140eb9313c0d1bb31f8a761d9c062c56733a61
ToppCelldroplet-Spleen-nan-21m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.96e-041713439498c35b2a2c3a339dc8c5d49c8ec20d8ad52753
ToppCelldroplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A3 GSR

2.96e-04171343ed5886d6aa87b2d73469d39dc217227bd4d4c918
ToppCelldroplet-Spleen-nan-21m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

2.96e-04171343db544252f98e073e5bb4bec4a110cd58e6434435
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

TTC39A IL3RA UGCG

2.96e-0417134372c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TDRD10 DOCK6 IL3RA

2.96e-04171343b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCellCOVID_vent-Lymphocytic-Dendritic-pDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

TTC39A IL3RA UGCG

2.96e-04171343779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCellCOVID_vent-Lymphocytic-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

TTC39A IL3RA UGCG

2.96e-04171343debbb071d260639b16269c94d172766908325c58
ToppCelldroplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A1 GSR

2.96e-0417134300739085fdbc4d64c9faacba2c2adeab580dd2b1
ToppCellCOVID-pDC|COVID / Condition, Cell_class and T cell subcluster

TTC39A IL3RA UGCG

3.01e-041723433ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCell390C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TTC39A IL3RA UGCG

3.01e-041723433f894c74916d49a995b2d4651ca1c6733c14ce9c
ToppCellmild_COVID-19-pDC|World / disease group, cell group and cell class (v2)

TTC39A IL3RA UGCG

3.01e-04172343dab2f1a05c7df58d9387b13271b3f1f1583f9ac3
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTC39A IL3RA UGCG

3.01e-04172343b84610f1e5889a655652800c2b3270d264bfe1a9
ToppCellCOVID-pDC-|COVID / Condition, Cell_class and T cell subcluster

TTC39A IL3RA UGCG

3.01e-04172343a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCelldroplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE ATP1A1 GSR

3.01e-041723435f58ff6cac32546d07b2a49ed250b6c7aa417188
ToppCellwk_15-18-Hematologic-Myeloid-pDC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TTC39A IL3RA UGCG

3.06e-04173343b571970e3ba88afc07041c5692ccfd85fc39e796
ToppCelldroplet-Lung-nan-21m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

3.11e-04174343763ca53339d9e236da8463f2a9d1bd39d4385d75
ToppCellsevere_influenza-pDC|severe_influenza / disease group, cell group and cell class (v2)

TTC39A IL3RA UGCG

3.11e-04174343d8d2ded5812ed3b3db4109585714a6513c13326a
ToppCelldroplet-Lung-LUNG-1m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A1 GSR

3.17e-04175343c8cfe0ac0c1ac447c626a623cc49692a0b177a1c
ToppCellmild_COVID-19-pDC|mild_COVID-19 / disease group, cell group and cell class (v2)

TTC39A IL3RA UGCG

3.17e-04175343b87f279a7519710146c49d6acccb0adedc195965
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A1 GSR

3.17e-0417534361fbd8f685d3daad46449e4c0386a38886496566
ToppCell10x5'-blood-Lymphocytic_T_CD4-Tfh|blood / Manually curated celltypes from each tissue

ATP1A3 FASTKD1 PRSS21

3.17e-04175343d7e24ac683ff36f7ce3d1151353d3d4a6f2b63bf
ToppCelldroplet-Spleen-nan-24m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE ATP1A3 GSR

3.27e-041773435f20a1a875d6f85ec07b097e6afdb07c2f8f88ff
ToppCellHealthy/Control-pDC|Healthy/Control / Disease group and Cell class

TTC39A IL3RA UGCG

3.33e-04178343072b346c6bbd63f00efaceda486400a669b3ec48
ToppCellfacs-Marrow-KLS-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TTC39A NEK6

3.33e-041783436bad4439a1692332f70135ff446a1048fa4c399d
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTC39A IL3RA UGCG

3.33e-0417834327d9826b83be67b780901429470ceb013e9039c0
ToppCellfacs-Marrow-KLS-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TTC39A NEK6

3.33e-041783433f6feb4ed7779cf5684f52939350b41d7718c3c6
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HFE TTC39A NEK6

3.38e-041793439dea57494d59abd6e8abf34e31faf53462ea0fa0
ComputationalGenes in the cancer module 237.

USP34 PIK3CA FASTKD1

1.59e-0458203MODULE_237
DrugDigoxin

ATP1A1 ATP1A3 NR1H4 GSR

5.72e-0746334ctd:D004077
Drugferene

GSR KRIT1

1.22e-054332CID000133222
Drug22,23-dihydrobufalin

ATP1A1 ATP1A3

2.03e-055332CID000195392
Drug3-acetylstrophanthin

ATP1A1 ATP1A3

2.03e-055332CID003082282
Drugthevetin A

ATP1A1 ATP1A3

2.03e-055332CID000441873
DrugETH157

ATP1A1 ATP1A3

3.04e-056332CID000563154
Drugdihydrodigitoxigenin

ATP1A1 ATP1A3

4.26e-057332CID000107549
DrugLycorine hydrochloride [2188-68-3]; Up 200; 12.4uM; PC3; HT_HG-U133A

PUS3 HAS2 UTP25 UGCG

6.89e-051533343808_UP
DrugAC1MBZB6

ATP1A1 ATP1A3

7.29e-059332CID002733620
DrugNSC89595

ATP1A1 ATP1A3 PIK3CA

7.70e-0557333CID000002464
Drugouabagenin

ATP1A1 ATP1A3

1.11e-0411332CID000010497
DrugCloperastine hydrochloride [14984-68-0]; Up 200; 11uM; MCF7; HT_HG-U133A

ATP10B NUP188 NR1H4 PRSS21

1.38e-041833344732_UP
DrugN-acetylglucosaminolactone

PIK3CA GSR KRIT1

1.42e-0470333CID000087901
DrugA-32686

ATP1A1 ATP1A3

1.57e-0413332CID000004951
Drug2-propylpentanoic acid; Down 200; 1000uM; PC3; HG-U133A

HFE HAS2 CENPN ECPAS

1.66e-04192334458_DN
DrugAG-013608 [351320-38-2]; Down 200; 10uM; PC3; HT_HG-U133A

EFHC2 HFE ECPAS GEMIN8

1.69e-041933345909_DN
DrugNifedipine [21829-25-4]; Up 200; 11.6uM; PC3; HT_HG-U133A

USP34 HAS2 UTP25 UGCG

1.72e-041943341814_UP
Drug5213008; Up 200; 18uM; MCF7; HT_HG-U133A_EA

HFE DOCK6 KRIT1 UGCG

1.72e-04194334898_UP
DrugLuteolin [491-70-3]; Up 200; 14uM; MCF7; HT_HG-U133A

HFE NUP188 PUS3 ECPAS

1.72e-041943343379_UP
DrugNSC294864

ATP1A1 HAS2 ATP1A3

1.74e-0475333CID000325714
DrugDihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; MCF7; HT_HG-U133A

HFE USP34 ATP10B ECPAS

1.76e-041953342895_UP
DrugSulfaguanidine [57-67-0]; Up 200; 18.6uM; HL60; HG-U133A

HFE ECPAS KRIT1 UGCG

1.79e-041963341995_UP
DrugPirenperone [ 75444-65-4]; Up 200; 10.2uM; HL60; HT_HG-U133A

HFE USP34 ATP10B NUP188

1.83e-041973342455_UP
DrugSulfachloropyridazine [80-32-0]; Up 200; 14uM; PC3; HT_HG-U133A

EFHC2 HFE ATP10B ATP1A3

1.83e-041973343769_UP
DrugPheniramine maleate [132-20-7]; Down 200; 11.2uM; HL60; HG-U133A

HFE USP34 ACOT8 GSR

1.83e-041973341992_DN
DrugAcebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A

HFE TTC39A NUP188 DOCK6

1.83e-041973344976_UP
DrugAC1L99R9

ACOT8 NR1H4

1.83e-0414332CID000440685
DrugEnalapril maleate [76095-16-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A

HFE USP34 DOCK6 KRIT1

1.86e-041983347428_UP
DrugNovobiocin sodium salt [1476-53-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A

ATP10B TTC39A NUP188 ATP1A3

1.86e-041983344392_UP
DrugHomatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A

HFE ATP1A3 ECPAS GEMIN8

1.86e-041983345477_UP
DrugKanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; HL60; HG-U133A

ACOT8 UTP25 GSR KRIT1

1.86e-041983341609_DN
DrugMolsidomine [25717-80-0]; Up 200; 16.6uM; HL60; HG-U133A

HFE USP34 GSR KRIT1

1.86e-041983341711_UP
Drugalpha-Santonin [481-06-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A

HFE ATP10B TTC39A ECPAS

1.86e-041983344353_UP
DrugClenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A

HFE ATP10B ATP1A3 DOCK6

1.90e-041993343228_UP
DrugIdarubicin

NR1H4 GSR

2.11e-0415332ctd:D015255
DrugNSC-84513

ATP1A1 ATP1A3

2.11e-0415332CID000256927
DrugNdCl3

GSR KRIT1

2.11e-0415332CID000066204
Diseasecerebral cavernous malformation (is_implicated_in)

PIK3CA KRIT1

3.64e-063332DOID:0060669 (is_implicated_in)
DiseaseCerebral cavernous malformation

PIK3CA KRIT1

7.27e-064332cv:C2919945
DiseaseHereditary cavernous hemangioma of brain

PIK3CA KRIT1

7.27e-064332cv:C2931263
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A1 ATP1A3

2.54e-057332DOID:0060178 (implicated_via_orthology)
Diseasenervous system disease (implicated_via_orthology)

ATP1A1 ATP1A3

7.95e-0512332DOID:863 (implicated_via_orthology)
DiseaseAutosomal Dominant Parkinsonism

ATP1A3 GSR

4.50e-0428332C0752098
DiseaseAutosomal Dominant Juvenile Parkinson Disease

ATP1A3 GSR

4.50e-0428332C0752097
DiseaseParkinsonism, Experimental

ATP1A3 GSR

4.50e-0428332C0752101
DiseaseAutosomal Recessive Parkinsonism

ATP1A3 GSR

4.50e-0428332C0752100
DiseaseFamilial Juvenile Parkinsonism

ATP1A3 GSR

4.50e-0428332C0752104
DiseaseRamsay Hunt Paralysis Syndrome

ATP1A3 GSR

4.50e-0428332C0242423
DiseasePARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE

ATP1A3 GSR

4.50e-0428332C1868675
DiseaseParkinsonism, Juvenile

ATP1A3 GSR

5.17e-0430332C0752105
DiseaseParkinsonian Disorders

ATP1A3 GSR

5.17e-0430332C0242422
DiseaseVentricular Dysfunction, Left

ATP1A3 PIK3CA

5.17e-0430332C0242698
Disease3-hydroxy-1-methylpropylmercapturic acid measurement

EFHC2 USP34 ANO5 NEK6

6.20e-04352334EFO_0007015
Diseasecups of coffee per day measurement

ATP1A1 ATP1A3

9.21e-0440332EFO_0006782
Diseasehepatocellular carcinoma (is_implicated_in)

HFE PIK3CA NR1H4

1.08e-03181333DOID:684 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
QHKVHFMVSLDHSMW

ACOT8

246

O14734
HNMQFWHVLAAKMTF

ANO5

821

Q75V66
KVMWNTAVHSEFMHD

GSR

111

P00390
LHQAMEMKTWTIFHG

ATP10B

1241

O94823
TFNHHHAEMLMSWRV

NR1H4

456

Q96RI1
HAEMLMSWRVNDHKF

NR1H4

461

Q96RI1
KHWFSIYQMLEKHMQ

MDN1

3836

Q9NU22
AMAWMQSHHNAYRKA

GEMIN8

31

Q9NWZ8
MTVAHMWFDNQIHEA

ATP1A1

386

P05023
MFHQFEMIWAANQHN

KIAA1109

526

Q2LD37
LVYKFMNLANHHAMW

ECPAS

1081

Q5VYK3
MNLANHHAMWNSRKG

ECPAS

1086

Q5VYK3
HKSQHWGFCNNVMML

EFHC2

21

Q5JST6
IGYVHQVAKQMHIWM

NEK6

296

Q9HC98
KEMHHLQRMFLQNCW

KRIT1

616

O00522
HMFTVDFWTIMENHN

HFE

96

Q30201
FFFWHLKSEMHNKTV

PIK3CA

666

P42336
HSFMHWKMRSHFNRK

IL3RA

221

P26951
AWFFFQLMVKSMALH

DOCK6

931

Q96HP0
WIQHDHMYLDNMTAK

FASTKD1

461

Q53R41
AMWFHKHHLWMTYEA

HAS2

366

Q92819
FHQHQKVWEVFQMSK

CENPN

76

Q96H22
AAHHVFRWDIMVFFM

UGCG

306

Q16739
MTVAHMWFDNQIHEA

ATP1A3

376

P13637
YMLVKMSHHVWTAQN

EXOC1

611

Q9NV70
HFSLFHMAANMYVLW

PARL

216

Q9H300
YLMQNWEHVLHLMNH

UTP25

486

Q68CQ4
LWANHAVKTHMLYSM

PUS3

351

Q9BZE2
AMFKQAMRHWEKHTC

TLL1

176

O43897
WAMHVTEALHQNMQA

TDRD10

211

Q5VZ19
MMVNCHAHFWTTKAF

RDH10

166

Q8IZV5
NFMKEWHFHLPQLMR

NUP188

1461

Q5SRE5
MSFKWHSSFRNHLRM

ZNF57

511

Q68EA5
HHFEWIQKLMAQSGM

PRSS21

276

Q9Y6M0
LIHNWVMAQHMQSHA

USP34

1861

Q70CQ2
QHWKQFHHMCYWELM

TTC39A

346

Q5SRH9
MFIIWNKMNHHGRSS

TEX46

76

H3BTG2