Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	deubiquitinase activity	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 PRPF8 ATXN3L USP17L22 USP17L15	2.25e-09	124	280	14	GO:0101005
GeneOntologyMolecularFunction	cysteine-type deubiquitinase activity	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 ATXN3L USP17L22 USP17L15	7.53e-09	114	280	13	GO:0004843
GeneOntologyMolecularFunction	ubiquitin-like protein peptidase activity	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 PRPF8 ATXN3L USP17L22 USP17L15	8.34e-09	137	280	14	GO:0019783
GeneOntologyMolecularFunction	cysteine-type peptidase activity	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 ATXN3L USP17L22 USP17L15	3.36e-06	192	280	13	GO:0008234
GeneOntologyMolecularFunction	glycerol channel activity	AQP7B AQP7P3 AQP7	9.16e-05	7	280	3	GO:0015254
GeneOntologyMolecularFunction	gamma-tubulin binding	PDE4B TUBGCP2 WASHC1 WASH3P BRSK1	1.80e-04	38	280	5	GO:0043015
GeneOntologyMolecularFunction	AMP binding	ACSS1 PFKL PFKM PRKAG3	1.88e-04	21	280	4	GO:0016208
GeneOntologyMolecularFunction	urea transmembrane transporter activity	AQP7B AQP7P3 AQP7	2.15e-04	9	280	3	GO:0015204
GeneOntologyMolecularFunction	glycerol transmembrane transporter activity	AQP7B AQP7P3 AQP7	2.15e-04	9	280	3	GO:0015168
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	CEACAM6 AQP7B AQP7P3 AQP7 SLC44A1 SLC18A2	4.45e-04	70	280	6	GO:1901618
GeneOntologyMolecularFunction	6-phosphofructokinase activity	PFKL PFKM	5.82e-04	3	280	2	GO:0003872
GeneOntologyMolecularFunction	GTPase binding	RGPD4 DOCK11 RGPD1 PICALM KIF3B RGPD3 RAF1 DMXL2 NSF AMBRA1 GRIA1 KIF3A RAB3GAP1 IPO9	5.98e-04	360	280	14	GO:0051020
GeneOntologyMolecularFunction	small GTPase binding	RGPD4 DOCK11 RGPD1 PICALM KIF3B RGPD3 RAF1 DMXL2 NSF GRIA1 KIF3A RAB3GAP1 IPO9	6.40e-04	321	280	13	GO:0031267
GeneOntologyMolecularFunction	polyol transmembrane transporter activity	AQP7B AQP7P3 AQP7	7.03e-04	13	280	3	GO:0015166
GeneOntologyMolecularFunction	cytoskeletal protein binding	KIF21B PDE4B MYO7B APC2 OBSCN CEACAM6 TOGARAM1 TUBGCP2 PICALM STIM1 SPTBN5 SHROOM4 KIF3B NAV3 ANK3 COBLL1 WASHC1 TOGARAM2 BRSK2 RDX GRIA1 REEP3 KIFC2 PTPRT KIF3A WASH3P SYNE3 BRSK1 SNTB2	8.25e-04	1099	280	29	GO:0008092
GeneOntologyBiologicalProcess	protein deubiquitination	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 ATXN3L USP17L22 USP17L15	1.46e-08	125	278	13	GO:0016579
GeneOntologyBiologicalProcess	protein modification by small protein removal	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 ATXN3L USP17L22 USP17L15	8.00e-08	144	278	13	GO:0070646
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	APC2 TOGARAM1 NCKAP5 TUBGCP2 CUL7 ATAT1 KIF3B NAV3 ULK4 PLK3 CHMP4C CFAP47 ANK3 WASHC1 HAUS5 TOGARAM2 BRSK2 KIFC2 KIF3A ATXN3L WASH3P HAUS1 CFAP74 CEP152 CTNNB1 BRSK1 CDC20	1.76e-06	720	278	27	GO:0000226
GeneOntologyBiologicalProcess	organelle assembly	MYBPH BRIX1 OBSCN TOGARAM1 TUBGCP2 ATAT1 KIF3B NRXN2 CASKIN1 ULK4 CPLANE1 AP3D1 KNL1 CHMP4C CFAP47 RPGRIP1L ATG7 WASHC1 HAUS5 LAMA5 RDX RNF213 AMBRA1 WBP2NL KIFC2 KIF3A WASH3P RAB3GAP1 HAUS1 HGS CFAP74 CEP152 LRBA CDC20 TCTN2	4.59e-06	1138	278	35	GO:0070925
GeneOntologyBiologicalProcess	microtubule-based process	KIF21B APC2 TOGARAM1 NCKAP5 TUBGCP2 CUL7 ATAT1 KIF3B VPS13A NAV3 KLHL42 ULK4 PLK3 AP3D1 CHMP4C CFAP47 ANK3 WASHC1 HAUS5 TOGARAM2 BRSK2 KIFC2 KIF3A ATXN3L WASH3P HAUS1 CFAP74 CEP152 CTNNB1 BRSK1 CDC20 BBS12 ROPN1	6.59e-06	1058	278	33	GO:0007017
GeneOntologyBiologicalProcess	cell cycle process	TRIM75 MCM3 WNT4 TUBGCP2 CUL7 ANKLE2 BID BLM TAOK3 KIF3B MTA3 ANAPC1 STRADA MAD1L1 NIPBL PLK3 PHIP KNL1 CHMP4C HUS1B ANK3 WASHC1 HAUS5 BRSK2 RDX AMBRA1 SIAH1 MED1 REEP3 KIFC2 KIF3A CCNG1 WASH3P HAUS1 ZFYVE26 CEP152 CTNNB1 BRSK1 CDC20 EIF4G3	1.06e-05	1441	278	40	GO:0022402
GeneOntologyBiologicalProcess	supramolecular fiber organization	MYBPH EPPK1 MYO7B APC2 OBSCN TOGARAM1 NCKAP5 WNT4 TUBGCP2 BID SPTBN5 SHROOM4 AEBP1 KRT77 NAV3 PKP1 ARHGAP25 CX3CL1 PLK3 FOXC2 WASHC4 WASHC1 HAUS5 TOGARAM2 RDX SIAH1 SEMA5A WASH3P HAUS1 KANK3	1.62e-05	957	278	30	GO:0097435
GeneOntologyBiologicalProcess	behavior	MORC1 MAFG PDE4D ATP8A2 CDH23 CEACAM6 GPR52 BRINP1 PICALM NRXN2 SYNJ1 SCN3A VPS13A SLC17A7 ULK4 CELF6 VLDLR DSCAM ATG7 GRIA1 VWA1 ATXN3L SLC18A2 CSNK1E BRSK1 MBD5 PBX3 BBS12	3.02e-05	891	278	28	GO:0007610
GeneOntologyBiologicalProcess	metanephros development	LGR4 WNT4 GREB1L NIPBL FOXC2 FRAS1 SIX1 CTNNB1	4.35e-05	95	278	8	GO:0001656
GeneOntologyBiologicalProcess	synaptic vesicle localization	PICALM SYNJ1 AP3D1 BRSK2 RAB3GAP1 CTNNB1 BRSK1	4.77e-05	71	278	7	GO:0097479
GeneOntologyBiologicalProcess	mitotic cell cycle checkpoint signaling	BLM TAOK3 MAD1L1 PLK3 KNL1 CHMP4C HUS1B CCNG1 BRSK1 CDC20	7.59e-05	163	278	10	GO:0007093
GeneOntologyBiologicalProcess	mitotic cell cycle process	MCM3 CUL7 ANKLE2 BID BLM TAOK3 KIF3B MTA3 ANAPC1 MAD1L1 NIPBL PLK3 PHIP KNL1 CHMP4C HUS1B ANK3 BRSK2 RDX AMBRA1 REEP3 KIFC2 CCNG1 ZFYVE26 BRSK1 CDC20	9.83e-05	854	278	26	GO:1903047
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	USP17L21 TRIM75 USP17L20 USP17L19 CUL7 HMG20B USP17L18 TULP4 USP17L17 UBR5 ANAPC1 KLHL42 USP17L13 USP17L12 ATG7 USP17L11 WASHC1 USP17L24 USP17L5 RNF213 AMBRA1 SIAH1 MED1 ATXN3L WASH3P CTNNB1 CDC20 USP17L22 USP17L15	1.06e-04	1009	278	29	GO:0070647
GeneOntologyBiologicalProcess	mitotic cell cycle	MCM3 BRINP1 TUBGCP2 CUL7 ANKLE2 BID BLM TAOK3 KIF3B MTA3 ANAPC1 MAD1L1 NIPBL PLK3 PHIP KNL1 CHMP4C HUS1B ANK3 BRSK2 RDX AMBRA1 REEP3 KIFC2 CCNG1 ZFYVE26 CTNNB1 BRSK1 CDC20	1.15e-04	1014	278	29	GO:0000278
GeneOntologyBiologicalProcess	vesicle localization	TANC2 PICALM KIF3B SYNJ1 MAP4K2 AP3D1 BRSK2 KIF3A RAB3GAP1 HGS CTNNB1 BRSK1	1.41e-04	247	278	12	GO:0051648
GeneOntologyBiologicalProcess	negative regulation of relaxation of cardiac muscle	PDE4B PDE4D	1.81e-04	2	278	2	GO:1901898
GeneOntologyBiologicalProcess	sequestering of neurotransmitter	SLC17A7 SLC18A2	1.81e-04	2	278	2	GO:0042137
GeneOntologyBiologicalProcess	positive regulation of glucokinase activity	RGPD4 RGPD1 RGPD3	1.92e-04	9	278	3	GO:0033133
GeneOntologyBiologicalProcess	cAMP catabolic process	PDE4A PDE4B PDE4D	1.92e-04	9	278	3	GO:0006198
GeneOntologyBiologicalProcess	glycerol transmembrane transport	AQP7B AQP7P3 AQP7	1.92e-04	9	278	3	GO:0015793
GeneOntologyBiologicalProcess	synaptic vesicle clustering	PICALM BRSK2 CTNNB1 BRSK1	1.95e-04	22	278	4	GO:0097091
GeneOntologyBiologicalProcess	G2/M transition of mitotic cell cycle	BLM TAOK3 MTA3 PLK3 CHMP4C HUS1B BRSK2 CCNG1 BRSK1	2.26e-04	152	278	9	GO:0000086
GeneOntologyBiologicalProcess	spindle assembly	TUBGCP2 KIF3B CHMP4C WASHC1 HAUS5 KIFC2 WASH3P HAUS1 CDC20	2.37e-04	153	278	9	GO:0051225
GeneOntologyBiologicalProcess	fluid transport	AHCYL1 AQP7B AQP7P3 SCNN1B AQP7	2.43e-04	42	278	5	GO:0042044
GeneOntologyBiologicalProcess	positive regulation of hexokinase activity	RGPD4 RGPD1 RGPD3	2.71e-04	10	278	3	GO:1903301
GeneOntologyBiologicalProcess	post-translational protein modification	USP17L21 TRIM75 USP17L20 USP17L19 CUL7 HMG20B USP17L18 TULP4 USP17L17 UBR5 ANAPC1 KLHL42 USP17L13 USP17L12 ATG7 USP17L11 WASHC1 USP17L24 USP17L5 RNF213 AMBRA1 SIAH1 MED1 ATXN3L WASH3P CTNNB1 CDC20 USP17L22 USP17L15	3.03e-04	1074	278	29	GO:0043687
GeneOntologyBiologicalProcess	branching involved in ureteric bud morphogenesis	LGR4 WNT4 GREB1L LAMA5 SIX1 CTNNB1	3.09e-04	68	278	6	GO:0001658
GeneOntologyBiologicalProcess	regulation of supramolecular fiber organization	APC2 TOGARAM1 WNT4 SPTBN5 AEBP1 NAV3 CX3CL1 WASHC4 WASHC1 HAUS5 TOGARAM2 RDX SEMA5A WASH3P HAUS1 KANK3	3.20e-04	438	278	16	GO:1902903
GeneOntologyCellularComponent	centrosome	PDE4B PDE4D CEP85L CDH23 MCM3 TUBGCP2 CUL7 KIF3B MAD1L1 PLK3 TCEA2 RPGRIP1L WASHC1 HAUS5 BRSK2 KIF3A WASH3P HAUS1 SLC18A2 KIAA1217 ZFYVE26 MZT2A CEP152 CTNNB1 BRSK1 CDC20	1.59e-05	770	280	26	GO:0005813
GeneOntologyCellularComponent	microtubule organizing center	PDE4B PDE4D CEP85L CDH23 MCM3 TOGARAM1 TUBGCP2 CUL7 KIF3B MAD1L1 PLK3 TCEA2 RPGRIP1L WASHC1 HAUS5 BRSK2 KIFC2 KIF3A WASH3P HAUS1 SLC18A2 KIAA1217 ZFYVE26 MZT2A CEP152 CTNNB1 BRSK1 CDC20	4.68e-05	919	280	28	GO:0005815
GeneOntologyCellularComponent	nuclear pore nuclear basket	RGPD4 RGPD1 RGPD3 MAD1L1	8.31e-05	18	280	4	GO:0044615
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	RGPD4 USP17L21 AHCYL1 USP17L20 RGPD1 USP17L19 ANKLE2 RYR1 EPM2AIP1 USP17L18 STIM1 OR8A1 USP17L17 RGPD3 NUP210 VPS13A NAV3 RFT1 MYRF NOTCH3 USP17L13 USP17L12 USP17L11 USP17L5 GRIA1 PLCD4 REEP3 ATXN3L RAB3GAP1 SYNE3 ASPH LRBA USP17L22 USP17L15 SLC35B1	9.88e-05	1327	280	35	GO:0042175
GeneOntologyCellularComponent	microtubule	KIF21B APC2 TOGARAM1 NCKAP5 TUBGCP2 ATAT1 STIM1 KIF3B SYNJ1 NAV3 CHMP4C RPGRIP1L HAUS5 TOGARAM2 REEP3 KIFC2 KIF3A HAUS1 SNTB2	1.13e-04	533	280	19	GO:0005874
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD4 RGPD1 RGPD3	1.27e-04	8	280	3	GO:1990723
GeneOntologyCellularComponent	nuclear inclusion body	RGPD4 RGPD1 RGPD3 ATXN3L	1.29e-04	20	280	4	GO:0042405
GeneOntologyCellularComponent	spindle	TRIM75 TUBGCP2 ATAT1 KIF3B MAD1L1 KLHL42 PYCR3 PLK3 CHMP4C HAUS5 KIFC2 KIF3A HAUS1 MZT2A CTNNB1 MAPKBP1 CDC20	2.24e-04	471	280	17	GO:0005819
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD4 RGPD1 RGPD3	2.66e-04	10	280	3	GO:0044614
GeneOntologyCellularComponent	supramolecular fiber	MYBPH KIF21B PDE4B PDE4D EPPK1 APC2 OBSCN TOGARAM1 NCKAP5 TUBGCP2 ATAT1 RYR1 STIM1 SHROOM4 KIF3B SYNJ1 KRT77 NAV3 PKP1 CHMP4C COL6A3 RPGRIP1L ANK3 HAUS5 TOGARAM2 REEP3 KIFC2 KIF3A HAUS1 CTNNB1 SNTB2	2.67e-04	1179	280	31	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	MYBPH KIF21B PDE4B PDE4D EPPK1 APC2 OBSCN TOGARAM1 NCKAP5 TUBGCP2 ATAT1 RYR1 STIM1 SHROOM4 KIF3B SYNJ1 KRT77 NAV3 PKP1 CHMP4C COL6A3 RPGRIP1L ANK3 HAUS5 TOGARAM2 REEP3 KIFC2 KIF3A HAUS1 CTNNB1 SNTB2	3.00e-04	1187	280	31	GO:0099081
GeneOntologyCellularComponent	nucleotide-activated protein kinase complex	SESN2 PRKAG3 PRKAB1	3.62e-04	11	280	3	GO:0031588
GeneOntologyCellularComponent	cell cortex	RYR1 STIM1 SPTBN5 SHROOM4 EXOC3L1 PDZD4 WASHC1 RDX FRYL PPFIA3 AQP7 WASH3P ASPH CTNNB1	5.15e-04	371	280	14	GO:0005938
GeneOntologyCellularComponent	6-phosphofructokinase complex	PFKL PFKM	5.32e-04	3	280	2	GO:0005945
GeneOntologyCellularComponent	kinesin II complex	KIF3B KIF3A	5.32e-04	3	280	2	GO:0016939
GeneOntologyCellularComponent	beta-catenin destruction complex	APC2 SIAH1 CTNNB1	6.16e-04	13	280	3	GO:0030877
GeneOntologyCellularComponent	endoplasmic reticulum tubular network	STIM1 REEP3 RAB3GAP1 ASPH	7.46e-04	31	280	4	GO:0071782
GeneOntologyCellularComponent	annulate lamellae	RGPD4 RGPD1 RGPD3	7.76e-04	14	280	3	GO:0005642
GeneOntologyCellularComponent	catenin complex	APC2 CDH23 CDH19 CTNNB1	8.43e-04	32	280	4	GO:0016342
GeneOntologyCellularComponent	WASH complex	WASHC4 WASHC1 WASH3P	9.60e-04	15	280	3	GO:0071203
GeneOntologyCellularComponent	BLOC-1 complex	WASHC4 WASHC1 WASH3P	1.67e-03	18	280	3	GO:0031083
Domain	HABP4_PAI-RBP1	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22	2.09e-17	16	272	11	PF04774
Domain	HABP4_PAIRBP1-bd	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22	2.09e-17	16	272	11	IPR006861
Domain	USP_CS	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22	2.70e-09	66	272	11	IPR018200
Domain	USP_1	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22	5.17e-09	70	272	11	PS00972
Domain	UCH	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22	6.04e-09	71	272	11	PF00443
Domain	USP_2	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22	6.04e-09	71	272	11	PS00973
Domain	USP_dom	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22	7.03e-09	72	272	11	IPR028889
Domain	Peptidase_C19_UCH	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22	7.03e-09	72	272	11	IPR001394
Domain	USP_3	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22	7.03e-09	72	272	11	PS50235
Domain	-	APC2 MROH5 TOGARAM1 CUL7 PKP1 ULK4 NIPBL AP3D1 TOGARAM2 HEATR5A FRYL IPO9 CTNNB1 LRBA	4.96e-06	222	272	14	1.25.10.10
Domain	ARM-type_fold	DOCK11 APC2 MROH5 TOGARAM1 CUL7 PKP1 ULK4 NIPBL AP3D1 TOGARAM2 NBEA HEATR5A FRYL IPO9 CTNNB1 LRBA EIF4G3	1.06e-05	339	272	17	IPR016024
Domain	ARM-like	APC2 MROH5 TOGARAM1 CUL7 PKP1 ULK4 NIPBL AP3D1 TOGARAM2 NBEA HEATR5A FRYL IPO9 CTNNB1 LRBA	1.06e-05	270	272	15	IPR011989
Domain	PH_dom-like	RGPD4 DOCK11 MYO7B RGPD1 OBSCN SPTBN5 ARHGAP22 PTPN14 RGPD3 ARHGAP25 AGAP3 PHLDB3 RDX PLCD4 WBP2NL NBEA LRBA SNTB2	5.68e-05	426	272	18	IPR011993
Domain	GCC2_Rab_bind	RGPD4 RGPD1 RGPD3	1.02e-04	7	272	3	IPR032023
Domain	Rab_bind	RGPD4 RGPD1 RGPD3	1.02e-04	7	272	3	PF16704
Domain	DUF1088	NBEA LRBA	2.11e-04	2	272	2	PF06469
Domain	DUF1088	NBEA LRBA	2.11e-04	2	272	2	IPR010508
Domain	-	RGPD4 RGPD1 RGPD3	3.40e-04	10	272	3	1.10.220.60
Domain	GRIP	RGPD4 RGPD1 RGPD3	4.62e-04	11	272	3	PF01465
Domain	Grip	RGPD4 RGPD1 RGPD3	4.62e-04	11	272	3	SM00755
Domain	HEAT_REPEAT	TOGARAM1 ULK4 NIPBL AP3D1 HEATR5A EIF4G3	5.42e-04	70	272	6	PS50077
Domain	Ran_BP1	RGPD4 RGPD1 RGPD3	6.10e-04	12	272	3	PF00638
Domain	RANBD1	RGPD4 RGPD1 RGPD3	6.10e-04	12	272	3	PS50196
Domain	GRIP	RGPD4 RGPD1 RGPD3	6.10e-04	12	272	3	PS50913
Domain	GRIP_dom	RGPD4 RGPD1 RGPD3	6.10e-04	12	272	3	IPR000237
Domain	Phosphofructokinase_CS	PFKL PFKM	6.28e-04	3	272	2	IPR015912
Domain	PFK	PFKL PFKM	6.28e-04	3	272	2	PF00365
Domain	Phosphofructokinase_dom	PFKL PFKM	6.28e-04	3	272	2	IPR000023
Domain	6-Pfructokinase_euk	PFKL PFKM	6.28e-04	3	272	2	IPR009161
Domain	PHOSPHOFRUCTOKINASE	PFKL PFKM	6.28e-04	3	272	2	PS00433
Domain	ATP_PFK	PFKL PFKM	6.28e-04	3	272	2	IPR022953
Domain	RanBD	RGPD4 RGPD1 RGPD3	7.84e-04	13	272	3	SM00160
Domain	Ran_bind_dom	RGPD4 RGPD1 RGPD3	7.84e-04	13	272	3	IPR000156
Pathway	REACTOME_RAS_PROCESSING	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	4.68e-11	45	213	11	MM15671
Pathway	REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 HGS CDC20 USP17L22 USP17L15	6.65e-06	191	213	13	MM15289
Pathway	REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 HGS CDC20 USP17L22 USP17L15	6.73e-06	221	213	14	M27578
Pathway	REACTOME_DEUBIQUITINATION	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 ATXN3L HGS CDC20 MBD5 USP17L22 USP17L15	1.07e-05	262	213	15	MM15286
Pathway	REACTOME_DEUBIQUITINATION	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 ATXN3L HGS CDC20 MBD5 USP17L22 USP17L15	1.26e-05	299	213	16	M27574
Pathway	REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE	ATAT1 KIF3B ALAS1 CRTC3 RPGRIP1L HAUS5 MED1 KIF3A PRKAG3 HAUS1 CSNK1E PRKAB1 CEP152 BBS12 TCTN2	4.63e-05	297	213	15	M27050
Pathway	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	MAFG KIF21B DOCK11 ZFPM1 HMG20B KIF3B MAFK KIFC2 KIF3A	6.53e-05	116	213	9	MM15715
Pubmed	DUB-1, a deubiquitinating enzyme with growth-suppressing activity.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	3.40e-18	21	288	11	8622927
Pubmed	DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	3.40e-18	21	288	11	14583620
Pubmed	DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	3.40e-18	21	288	11	11468161
Pubmed	The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	3.40e-18	21	288	11	8756639
Pubmed	Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	3.40e-18	21	288	11	12447969
Pubmed	DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	3.40e-18	21	288	11	18980247
Pubmed	JAK2 is required for induction of the murine DUB-1 gene.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	6.75e-18	22	288	11	9154835
Pubmed	DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	2.35e-17	24	288	11	8995226
Pubmed	Cdc25A and Dub3 in a high-stakes balancing act.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	2.51e-17	33	288	12	20228807
Pubmed	DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	14699124
Pubmed	The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	15780755
Pubmed	Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	17109758
Pubmed	Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	20715989
Pubmed	Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	9806828
Pubmed	The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	20403174
Pubmed	USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	19188362
Pubmed	Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	11941478
Pubmed	The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	20388806
Pubmed	The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	20368735
Pubmed	The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	10936051
Pubmed	The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	3.85e-17	34	288	12	21448158
Pubmed	Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	4.17e-17	25	288	11	21115691
Pubmed	Cytokine-regulated protein degradation by the ubiquitination system.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	5.82e-17	35	288	12	16611142
Pubmed	Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	5.82e-17	35	288	12	21239494
Pubmed	Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	7.17e-17	26	288	11	35816173
Pubmed	The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	8.66e-17	36	288	12	20147298
Pubmed	Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	1.27e-16	37	288	12	20228808
Pubmed	Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	3.14e-16	29	288	11	32527007
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RGPD4 TANC2 KIF21B PDE4A PDE4B DOCK11 APC2 RGPD1 MCM3 PICALM ITIH1 EMSY EPM2AIP1 KIF3B SYNJ1 UBR5 ANAPC1 CASKIN1 RGPD3 MAD1L1 PPP1R3F NIPBL DMXL2 ANK3 DSCAM NSF RDX GRIA1 SPATA20 NBEA PPFIA3 KIF3A NCOR2 KIAA1217 CTNNB1 BRSK1	5.48e-14	963	288	36	28671696
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	2.91e-13	50	288	11	31806660
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 PDE4A EPPK1 ACACA OBSCN ZFPM1 RYR1 TULP4 SYNJ1 CASKIN1 NFKB2 MAD1L1 ULK4 MYRF D2HGDH PLK3 AP3D1 AGAP3 PHLDB3 FRAS1 POLR2A LAMA5 AMBRA1 SPATA20 FRYL KIFC2 NCOR2 SYNE3 KANK3 ANKRD34A PCNX1 ZFYVE26 LRBA MAPKBP1 MBD5 SPEN	3.02e-12	1105	288	36	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TANC2 ACACA DOCK11 CEP85L TAB2 ATAT1 STIM1 PTPN14 SYNJ1 KRT77 MAD1L1 CCDC138 BICC1 AGAP3 RAF1 CRTC3 COBLL1 RALGAPB BRSK2 MAGI3 FRYL REEP3 MLXIPL IPO9 CSNK1E KIAA1217 CEP152 CDC20 EIF4G3	2.11e-10	861	288	29	36931259
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	TANC2 DOCK11 TUBGCP2 CUL7 PTPN14 UBR5 ANAPC1 CCDC138 AGAP3 RAF1 CRTC3 RALGAPB FRYL CSNK1E MOB1B HGS CEP152 CTNNB1 SNTB2	7.85e-09	446	288	19	24255178
Pubmed	Characterization of the murine orthologue of a novel human subtelomeric multigene family.	WASHC1 WASH3P WASH4P WASH2P	2.29e-08	5	288	4	11701968
Pubmed	Human subtelomeric WASH genes encode a new subclass of the WASP family.	WASHC1 WASH3P WASH4P WASH2P	6.82e-08	6	288	4	18159949
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	BRIX1 AHCYL1 PFKM ANKLE2 BLM STIM1 PCGF6 PTPN14 UBR5 NUP210 EIF2B4 CCDC138 VPS13A ALAS1 PYCR3 AP3D1 DMXL2 FRAS1 ANK3 NSF RALGAPB PRPF8 MRPL2 RAB3GAP1 SYNE3 BAZ2A CSNK1E HGS ASPH PANK4 TMEM131 CTNNB1 EIF4G3 SNTB2	9.96e-08	1487	288	34	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CPAMD8 PDE4D ACACA OBSCN WNT4 PFKL ATAT1 KLHL29 MTA3 TULP4 KCND3 NUP210 EIF2B4 MAD1L1 RPRD2 NOTCH3 AGAP3 SLC12A6 ANK3 ATG7 RALGAPB GPATCH2 RNF213 MAGI3 FRYL REEP3 NCOR2 KIAA1217 ASPH PANK4 LRBA EIF4G3 MBD5 PBX3	1.03e-07	1489	288	34	28611215
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	TANC2 DOCK11 TUBGCP2 SYNJ1 CASKIN1 NAV3 PKP1 C3 PHIP AP3D1 POLR2A WASHC1 RDX MAGI3 KIF3A NCOR2 WASH3P MZT2A	1.14e-07	475	288	18	31040226
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	MAFG RGPD4 PDE4D RGPD1 TUBGCP2 BCLAF3 BLM KANSL2 UBR5 ANAPC1 SERPINB12 RGPD3 MAD1L1 KLHL42 NIPBL KNL1 WASHC4 MAFK POLR2A HAUS5 AMBRA1 PRPF8 YARS2 HAUS1 CSNK1E MOB1B MZT2A CEP152 CDC20	1.37e-07	1155	288	29	20360068
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	NRXN2 VPS13A NAV3 MYRF RPGRIP1L COBLL1 PCNX1 SPEN FAIM2	1.89e-07	102	288	9	10231032
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TANC2 AHCYL1 PDE4B TAB2 PICALM HMG20B UBR5 STRADA NFKB2 EIF2B4 RPRD2 AP3D1 CHMP4C RAF1 CRTC3 WASHC4 POLR2A HAUS5 GPATCH2 MLXIPL HAUS1 CSNK1E KIAA1217 KCTD20 CTNNB1 CDC20 SNTB2	1.91e-07	1038	288	27	26673895
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TANC2 ACSS1 TOGARAM1 CUL7 SHROOM4 TULP4 TRPM3 NUP210 ARHGAP25 DMXL2 COBLL1 BRSK2 RNF213 MAGI3 RAB3GAP1 IPO9 CEP152 MBD5	1.97e-07	493	288	18	15368895
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	CUL7 PICALM EPM2AIP1 STIM1 PCGF6 TAOK3 MTA3 ANAPC1 STRADA CCDC138 CPLANE1 KNL1 RAF1 WASHC4 MAP4K3 BRSK2 GPATCH2 NCOR2 CSNK1E MOB1B PRKAB1 CTNNB1 BRSK1 CDC20 SNTB2	2.02e-07	910	288	25	36736316
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	TANC2 CDH23 MCM3 ANKLE2 BLM STIM1 TMEM161A PTPN14 KIF3B EIF2B4 C3 RFT1 AGAP3 RAF1 PHLDB3 CRTC3 RPGRIP1L ANK3 NSF COBLL1 AMBRA1 MED1 PRPF8 REEP3 KIF3A IPO9 HAUS1 ANKRD34A CTNNB1 BBS12 TCTN2	2.18e-07	1321	288	31	27173435
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ACACA CEP85L RGPD1 MCM3 TAB2 TUBGCP2 PFKM ANKLE2 EMSY PTPN14 SYNJ1 UBR5 CCDC138 CPLANE1 RPGRIP1L MAP4K3 HAUS5 MAGI3 HAUS1 CSNK1E KIAA1217 HGS TMEM131 CEP152	2.33e-07	853	288	24	28718761
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	PFKL CUL7 EMSY HMG20B BLM PCGF6 KANSL2 UBR5 ANAPC1 NFKB2 MAD1L1 PKP1 NOTCH3 FOXC2 NSF SMARCAL1 POLR2A SIX1 PRPF8 NCOR2 PANK4 CTNNB1 PBX3 SPEN	2.54e-07	857	288	24	25609649
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	OBSCN CUL7 RYR1 SPTBN5 NFKB2 NUP210 NOTCH3 AGAP3 LAMA5 RNF213 SLC22A18AS IPO9	2.64e-07	214	288	12	22199357
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	AHCYL1 ACACA MCM3 PFKL PFKM NPM3 BLM PCGF6 PTPN14 UBR5 SERPINB12 NFKB2 EIF2B4 PKP1 GMPPB NIPBL PYCR3 PHIP AP3D1 PHLDB3 WASHC4 MAP4K3 POLR2A AMBRA1 PRPF8 NCOR2 RAB3GAP1 IPO9 BAZ2A ASPH CDC20	3.65e-07	1353	288	31	29467282
Pubmed	The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.	RGPD4 RGPD1 KIF3B RGPD3	5.62e-07	9	288	4	9733766
Pubmed	The upstream conserved regions (UCRs) mediate homo- and hetero-oligomerization of type 4 cyclic nucleotide phosphodiesterases (PDE4s).	PDE4A PDE4B PDE4D	5.62e-07	3	288	3	24555506
Pubmed	Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect.	PDE4A PDE4B PDE4D	5.62e-07	3	288	3	10213096
Pubmed	Differential expression and function of phosphodiesterase 4 (PDE4) subtypes in human primary CD4+ T cells: predominant role of PDE4D.	PDE4A PDE4B PDE4D	5.62e-07	3	288	3	17404263
Pubmed	Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages.	PDE4A PDE4B PDE4D	5.62e-07	3	288	3	16034090
Pubmed	Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation.	PDE4A PDE4B PDE4D	5.62e-07	3	288	3	15585880
Pubmed	Critical role of PDE4D in beta2-adrenoceptor-dependent cAMP signaling in mouse embryonic fibroblasts.	PDE4A PDE4B PDE4D	5.62e-07	3	288	3	18508768
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	NCKAP5 CUL7 RYR1 TULP4 VPS13A NOTCH3 MAP4K3 RALGAPB NBEA PPFIA3 KIFC2 BAZ2A LRBA SPEN	7.67e-07	329	288	14	17474147
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TANC2 LGR4 TUBGCP2 CUL7 PAGE5 NPM3 HMG20B PTPN14 MTA3 UBR5 ANAPC1 PHIP KNL1 AGAP3 RAF1 VLDLR POLR2A HAUS5 GPATCH2 RNF213 AMBRA1 PPFIA3 ZNF711 NCOR2 BAZ2A PANK4 TCTN2	7.76e-07	1116	288	27	31753913
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	BRIX1 ZC3H14 PDE4D EPPK1 SYNJ1 RPRD2 PHIP AP3D1 NOTCH3 POLR2A SIX1 PRPF8 KIF3A CTNNB1	2.07e-06	358	288	14	32460013
Pubmed	Assessment of PDE4 Inhibitor-Induced Hypothermia as a Correlate of Nausea in Mice.	PDE4A PDE4B PDE4D	2.23e-06	4	288	3	34943270
Pubmed	Inhibition of cAMP-phosphodiesterase 4 (PDE4) potentiates the anesthetic effects of Isoflurane in mice.	PDE4A PDE4B PDE4D	2.23e-06	4	288	3	33609559
Pubmed	Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3.	PDE4A PDE4B PDE4D	2.23e-06	4	288	3	9371714
Pubmed	Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice.	PDE4A PDE4B PDE4D	2.23e-06	4	288	3	21670503
Pubmed	PAN-selective inhibition of cAMP-phosphodiesterase 4 (PDE4) induces gastroparesis in mice.	PDE4A PDE4B PDE4D	2.23e-06	4	288	3	32738081
Pubmed	A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs.	PDE4A PDE4B PDE4D	2.23e-06	4	288	3	8413254
Pubmed	Phosphodiesterase 4D is required for beta2 adrenoceptor subtype-specific signaling in cardiac myocytes.	PDE4A PDE4B PDE4D	2.23e-06	4	288	3	15644445
Pubmed	Role of phosphodiesterases in the shaping of sub-plasma-membrane cAMP oscillations and pulsatile insulin secretion.	PDE4A PDE4B PDE4D	2.23e-06	4	288	3	22946044
Pubmed	Ibudilast (AV411), and its AV1013 analog, reduce HIV-1 replication and neuronal death induced by HIV-1 and morphine.	PDE4A PDE4B PDE4D	2.23e-06	4	288	3	24732776
Pubmed	Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia.	PDE4A PDE4B PDE4D	2.23e-06	4	288	3	11839681
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	TAB2 ANKLE2 PICALM PTPN14 AP3D1 PDZD4 ANK3 CSNK1E KIAA1217 HGS TMEM131 LRBA	2.32e-06	263	288	12	34702444
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MCM3 TAB2 TUBGCP2 CUL7 EMSY BLM PTPN14 SYNJ1 UBR5 ANAPC1 NFKB2 KNL1 RPGRIP1L NCOR2 KIAA1217 CTNNB1 CDC20 SPEN	2.45e-06	588	288	18	38580884
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ACACA ANKLE2 PICALM STIM1 PTPN14 SLC12A6 PHLDB3 ANK3 MAP4K3 RALGAPB KIAA1217 HGS CTNNB1 LRBA SLC12A7	2.81e-06	421	288	15	36976175
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	RGPD4 RGPD1 RGPD3 ANK3	3.10e-06	13	288	4	31427429
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TANC2 AHCYL1 PDE4D PFKL PFKM NRXN2 SYNJ1 KCND3 CASKIN1 SLC17A7 AP3D1 AGAP3 SLC12A6 RAF1 DMXL2 ANK3 NSF MAP4K3 BRSK2 RDX GRIA1 NBEA PPFIA3 KIF3A MLXIPL SLC44A1 KIAA1217 CTNNB1 BRSK1 EIF4G3	3.44e-06	1431	288	30	37142655
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RGPD4 TANC2 AHCYL1 ACACA RGPD1 PFKL ANKLE2 STIM1 SYNJ1 KCND3 CASKIN1 RGPD3 NAV3 PKP1 AGAP3 DMXL2 ANK3 BRSK2 GRIA1 NBEA PPFIA3 RAB3GAP1 CSNK1E KIAA1217 CTNNB1 EIF4G3	3.60e-06	1139	288	26	36417873
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	EPPK1 APC2 PFKL TUBGCP2 ITIH1 UBR5 CASKIN1 AP3D1 AGAP3 CHMP4C GRIA1 MAGI3 PPFIA3 CSNK1E CTNNB1	3.63e-06	430	288	15	32581705
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	RGPD4 RGPD1 EMSY PCGF6 MTA3 RGPD3 MAD1L1 POLR2A KIAA1217	3.88e-06	146	288	9	23892456
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	USP17L21 USP17L20 CEACAM6 USP17L19 USP17L18 BCLAF3 SHROOM4 C9orf152 USP17L17 SCN3A USP17L13 USP17L12 USP17L11 TOGARAM2 USP17L5 SIAH1 ZNF711 USP17L22 USP17L15	4.24e-06	674	288	19	37196079
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	BRIX1 ACACA DOCK11 MCM3 BLM UBR5 ANAPC1 NUP210 RPRD2 POLR2A GPATCH2 AMBRA1 MED1 CTNNB1 CDC20	4.78e-06	440	288	15	34244565
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	APC2 PFKL ARHGAP22 KANSL2 MAD1L1 RPRD2 ALAS1 CPLANE1 PYCR3 NOTCH3 AGAP3 LAMA5 MAGI3 FRYL HGS CTNNB1 MAPKBP1	5.23e-06	560	288	17	21653829
Pubmed	Gene expression differences in mice divergently selected for methamphetamine sensitivity.	GRIA1 MED1 CSNK1E	5.55e-06	5	288	3	16104378
Pubmed	The cAMP-phosphodiesterase 4 (PDE4) controls β-adrenoceptor- and CFTR-dependent saliva secretion in mice.	PDE4A PDE4B PDE4D	5.55e-06	5	288	3	33944911
Pubmed	A mouse homolog of dunce, a gene important for learning and memory in Drosophila, is preferentially expressed in olfactory receptor neurons.	PDE4A PDE4B PDE4D	5.55e-06	5	288	3	8586960
Pubmed	C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest.	STRADA BRSK2 BRSK1	5.55e-06	5	288	3	18854318
Pubmed	Interaction between LIS1 and PDE4, and its role in cytoplasmic dynein function.	PDE4A PDE4B PDE4D	5.55e-06	5	288	3	21652625
Pubmed	Phosphodiesterase 4B negatively regulates endotoxin-activated interleukin-1 receptor antagonist responses in macrophages.	PDE4A PDE4B PDE4D	5.55e-06	5	288	3	28383060
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	RGPD4 RGPD1 RGPD3 NUP210	5.85e-06	15	288	4	14697343
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	ACACA TUBGCP2 CUL7 BID UBR5 NFKB2 SESN2 COG4 RAF1 NBEA RAB3GAP1 HAUS1	5.88e-06	288	288	12	23383273
Pubmed	A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L12 USP17L11 PCDHAC1	7.11e-06	119	288	8	28625976
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TAB2 CUL7 ANKLE2 BLM STIM1 PTPN14 NUP210 CCDC138 VPS13A KNL1 RPGRIP1L ANK3 POLR2A RALGAPB RNF213 NBEA PPFIA3 PTPRT NCOR2 IPO9 HAUS1 HGS SLC12A7 SNTB2	8.32e-06	1049	288	24	27880917
Pubmed	Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum.	PDE4A PDE4B PDE4D	1.10e-05	6	288	3	18923023
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RGPD4 ACACA RGPD1 HMG20B GREB1L SYNJ1 UBR5 ANAPC1 RGPD3 PYCR3 KNL1 RAF1 NCOR2 LRBA	1.21e-05	418	288	14	34709266
Pubmed	Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.	SYNJ1 NIPBL ANK3 CTNNB1	1.29e-05	18	288	4	33323119
Pubmed	NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.	MCM3 ANAPC1 NOTCH3 NBEA FRYL PRPF8 KIF3A LRBA	1.29e-05	129	288	8	23022380
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RGPD4 RGPD1 RGPD3	1.92e-05	7	288	3	9037092
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RGPD4 RGPD1 RGPD3	1.92e-05	7	288	3	21205196
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RGPD4 RGPD1 RGPD3	1.92e-05	7	288	3	24403063
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RGPD4 RGPD1 RGPD3	1.92e-05	7	288	3	23536549
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RGPD4 RGPD1 RGPD3	1.92e-05	7	288	3	12191015
Pubmed	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	RGPD4 RGPD1 RGPD3	1.92e-05	7	288	3	22821000
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD4 RGPD1 RGPD3	1.92e-05	7	288	3	15710750
Interaction	FLT3 interactions	BRIX1 USP17L21 EPPK1 USP17L20 USP17L19 PFKL PFKM USP17L18 USP17L17 NUP210 NIPBL AP3D1 USP17L12 USP17L11 PCDHAC1 RNF213 SIAH1 CTNNB1	5.19e-07	318	279	18	int:FLT3
Interaction	YWHAH interactions	TANC2 KIF21B ZC3H14 EPPK1 DOCK11 CEP85L TAB2 ATAT1 KCNK9 PYHIN1 STIM1 PTPN14 SYNJ1 KRT77 MAD1L1 CCDC138 BICC1 AGAP3 RAF1 CRTC3 RPGRIP1L COBLL1 RALGAPB MAGI3 FRYL MED1 REEP3 MLXIPL IPO9 CSNK1E KIAA1217 CEP152 LRBA CDC20 EIF4G3	4.08e-06	1102	279	35	int:YWHAH
Interaction	PCNT interactions	AHCYL1 ACACA CEP85L TUBGCP2 CCDC138 NIPBL DMXL2 RPGRIP1L RDX IPO9 SYNE3 CEP152 EIF4G3 ROPN1	7.25e-06	241	279	14	int:PCNT
Cytoband	4p16.1	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	1.04e-13	79	288	12	4p16.1
Cytoband	Ensembl 112 genes in cytogenetic band chr4p16	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	2.03e-08	222	288	12	chr4p16
GeneFamily	Wiskott-Aldrich Syndrome protein family	WASHC1 WASH3P WASH4P WASH2P	1.83e-05	16	187	4	14
GeneFamily	Ankyrin repeat domain containing	TANC2 ANKLE2 ANKRD18B CASKIN1 NFKB2 ANKDD1B NOTCH3 AGAP3 ANK3 KANK3 ANKRD34A	4.52e-05	242	187	11	403
GeneFamily	Mitogen-activated protein kinase kinase kinase kinases	MAP4K2 MAP4K3	1.04e-03	5	187	2	655
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF21B KIF3B KIFC2 KIF3A	1.29e-03	46	187	4	622
GeneFamily	WASH complex	WASHC4 WASHC1	1.55e-03	6	187	2	1331
GeneFamily	WD repeat domain containing	KIF21B TULP4 PHIP DMXL2 AMBRA1 NBEA LRBA MAPKBP1 CDC20	1.66e-03	262	187	9	362
GeneFamily	Phosphodiesterases	PDE4A PDE4B PDE4D	1.88e-03	24	187	3	681
GeneFamily	Sterile alpha motif domain containing	STIM1 CASKIN1 BICC1 PPFIA3 EPHA10	2.20e-03	88	187	5	760
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	AHCYL1 PFKM RYR1 PPP1R3F KNL1 RPGRIP1L GPATCH2	2.81e-03	181	187	7	694
GeneFamily	Components of oligomeric golgi complex	COG4 COG8	2.86e-03	8	187	2	493
GeneFamily	HAUS augmin like complex	HAUS5 HAUS1	2.86e-03	8	187	2	581
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	CPAMD8 C3	3.65e-03	9	187	2	1234
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEA LRBA	3.65e-03	9	187	2	1230
Coexpression	GERY_CEBP_TARGETS	USP17L21 USP17L20 USP17L19 PYHIN1 USP17L18 USP17L17 C3 USP17L13 USP17L12 ANK3 MAFK USP17L11 USP17L5 USP17L22 USP17L15	2.79e-10	160	286	15	MM1155
Coexpression	MADAN_DPPA4_TARGETS	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	2.55e-09	86	286	11	MM1312
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 PKP1 USP17L13 USP17L12 USP17L11 USP17L5 USP17L22 USP17L15	3.79e-09	112	286	12	MM1095
Coexpression	LAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2	PDE4D NCKAP5 PICALM VPS13A BICC1 ANK3 RNF213 SEMA5A NBEA KIAA1217 EIF4G3 MBD5	5.81e-07	176	286	12	M39223
Coexpression	BRUINS_UVC_RESPONSE_LATE	USP17L21 AHCYL1 PDE4B CEP85L USP17L20 MCM3 USP17L19 USP17L18 TAOK3 USP17L17 STRADA PPP1R3F BICC1 USP17L13 CHMP4C COL6A3 USP17L12 ATG7 USP17L11 WASHC1 GPATCH2 USP17L5 KIF3A YARS2 ATXN3L WASH3P SLC44A1 KANK3 ASPH KCTD20 USP17L22 USP17L15 SLC35B1	1.09e-06	1198	286	33	MM1062
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	ZC3H14 TOGARAM1 TAB2 ANKLE2 PICALM BLM TAOK3 UBR5 MAD1L1 VPS13A NAV3 NIPBL PHIP VLDLR DMXL2 WASHC4 RDX SEMA5A FRYL MED1 NCOR2 RAB3GAP1 TMEM131 EIF4G3 PBX3 SPEN	2.89e-06	856	286	26	M4500
Coexpression	LAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE	TANC2 PDE4D LGR4 TRPM3 BICC1 FRAS1 ANK3 MAP4K3 COBLL1 LRBA EIF4G3	3.04e-06	171	286	11	M39234
Coexpression	LAKE_ADULT_KIDNEY_C16_COLLECTING_SYSTEM_PRINCIPAL_CELLS_CORTEX	TANC2 PDE4D TRPM3 FRAS1 ANK3 COBLL1 MAGI3 NBEA LRBA MBD5	3.59e-06	141	286	10	M39235
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP	MAFG BRIX1 USP17L21 USP17L20 USP17L19 HMG20B USP17L18 STIM1 USP17L17 PKP1 KLHL42 SESN2 ALAS1 USP17L13 USP17L12 USP17L11 USP17L5 MAPKBP1 SLC12A7 USP17L22 USP17L15	1.00e-05	647	286	21	MM981
Coexpression	MARSON_BOUND_BY_FOXP3_STIMULATED	USP17L21 AHCYL1 USP17L20 MCM3 TAB2 USP17L19 PFKM PICALM EPM2AIP1 USP17L18 KANSL2 USP17L17 NUP210 SESN2 USP17L13 USP17L12 USP17L11 COBLL1 USP17L5 REEP3 RAB3GAP1 SYNE3 ASPH KCTD20 SLC41A1 USP17L22 BBS12 USP17L15	1.98e-05	1072	286	28	MM1031
Coexpression	GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_DN	TUBGCP2 STIM1 TMEM161A TAOK3 DMXL2 COBLL1 SMARCAL1 CCNG1 MAPKBP1	6.28e-05	158	286	9	M8993
Coexpression	GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP	PDE4A MTA3 NRXN2 VPS13A RPRD2 CELF6 SLC12A6 COBLL1 RBP1 SIAH1	6.56e-05	197	286	10	M3133
Coexpression	NAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_UP	ACSS1 MCM3 EMSY HMG20B KIF3B NUP210 EIF2B4 MAD1L1 GMPPB ATG7 SLC26A2 COBLL1 RALGAPB COG8 RAB3GAP1 SLC44A1 IPO9 TCTN2	6.62e-05	573	286	18	M41006
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN	PDE4A PDE4D OBSCN CEACAM6 BRINP1 CUL7 KCND3 MAD1L1 SLC17A7 CHRDL1 PYCR3 NOTCH3 DMXL2 ANK3 CILP MAFK RDX MRPL2 SLC22A18AS MLXIPL CSNK1E FAIM2 SNTB2 TCTN2	6.69e-05	909	286	24	M41018
Coexpression	GSE22886_TH1_VS_TH2_12H_ACT_UP	KIF21B ACACA ATP8A2 TRPM3 COL6A3 ANK3 RDX NBEA RAB3GAP1 TMEM131	7.14e-05	199	286	10	M4507
Coexpression	GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN	PFKL BCLAF3 UBR5 MAD1L1 NIPBL TCEA2 DMXL2 DSCAM MAFK PTPRT	7.14e-05	199	286	10	M8356
Coexpression	GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_UP	DOCK11 TAB2 TAOK3 MTA3 RPRD2 D2HGDH CRTC3 MAP4K3 COBLL1 PCNX1	7.44e-05	200	286	10	M9447
Coexpression	GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDC_UP	MYBPH KIF21B IGSF6 TUBGCP2 EMSY KRT77 PHIP AQP7 MAPKBP1 SLC41A1	7.44e-05	200	286	10	M3962
Coexpression	GSE8835_CD4_VS_CD8_TCELL_UP	AHCYL1 ACACA CUL7 BID ANAPC1 NUP210 PRPF8 ZNF667 TMEM131 TCTN2	7.44e-05	200	286	10	M6254
Coexpression	GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP	MAFG BRIX1 USP17L21 USP17L20 USP17L19 HMG20B EPM2AIP1 USP17L18 STIM1 USP17L17 PKP1 KLHL42 SESN2 ALAS1 CX3CL1 PLK3 USP17L13 USP17L12 MAFK SGCA USP17L11 POLR2A USP17L5 SIAH1 CCNG1 MAPKBP1 SLC12A7 USP17L22 USP17L15	8.28e-05	1226	286	29	MM979
Coexpression	RATTENBACHER_BOUND_BY_CELF1	CPAMD8 CEACAM6 BRINP1 PAGE5 BID STIM1 TULP4 NAV3 SIAH1 NBEA FRYL PRPF8 CSNK1E KIAA1217 SLC41A1	1.22e-04	444	286	15	M2505
Coexpression	PUJANA_BREAST_CANCER_LIT_INT_NETWORK	ACACA MCM3 EMSY HMG20B BLM PLK3 MED1	1.23e-04	101	286	7	M15356
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EMILIN2 NCKAP5 WNT4 IGSF10 AEBP1 C3 MYRF BICC1 VLDLR FRAS1 RBP1 SEMA5A	3.57e-09	191	281	12	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	AHCYL1 NCKAP5 TRPM3 ULK4 C3 MYRF BICC1 FRAS1 ANK3 COBLL1 SLC3A1	1.71e-08	176	281	11	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGSF10 AEBP1 SCN3A CHRDL1 BICC1 VLDLR COL6A3 CILP RBP1 GRIA1 FAIM2	3.96e-08	191	281	11	cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 EMILIN2 WNT4 AEBP1 C3 BICC1 VLDLR RBP1 SEMA5A SLC44A1 ASPH	5.16e-08	196	281	11	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGR4 IGSF10 NRXN2 AEBP1 NAV3 C3 BICC1 COL6A3 RBP1 SEMA5A VWA1	5.16e-08	196	281	11	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGR4 IGSF10 NRXN2 AEBP1 NAV3 C3 BICC1 COL6A3 RBP1 SEMA5A VWA1	5.16e-08	196	281	11	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	PDE4D ACACA UBR5 ANK3 MAP4K3 AMBRA1 MAGI3 NBEA LRBA EIF4G3 MBD5	6.03e-08	199	281	11	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 PDE4D ACACA NCKAP5 PTPN14 SCNN1B ANK3 LAMA5 MAGI3 KIAA1217	1.36e-07	170	281	10	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 CPAMD8 PDE4D GREB1L TRPM3 SCN3A SCNN1B FRAS1 ANK3 COBLL1	2.69e-07	183	281	10	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MCM3 NCKAP5 SCN3A RPGRIP1L WASHC1 PPFIA3 MRPL2 MOB1B LRBA	2.73e-07	140	281	9	af9efcbaeeae69fcdac4a15fa244728b65915564
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|368C / Donor, Lineage, Cell class and subclass (all cells)	CEACAM6 C9orf152 SCNN1B CPLANE1 LAMA5 MAGI3 NBEA KIAA1217 LRBA MAPKBP1	3.29e-07	187	281	10	b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CEACAM6 C9orf152 SCNN1B CPLANE1 LAMA5 MAGI3 NBEA KIAA1217 LRBA MAPKBP1	3.29e-07	187	281	10	61c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 CPAMD8 PDE4D GREB1L TRPM3 SCN3A SCNN1B FRAS1 ANK3 COBLL1	3.29e-07	187	281	10	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D PTPN14 BICC1 ANK3 COBLL1 AMBRA1 MAGI3 KIAA1217 LRBA MBD5	3.63e-07	189	281	10	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 PDE4D TRPM3 SCNN1B ULK4 ALAS1 FRAS1 ANK3 COBLL1 MOB1B	3.81e-07	190	281	10	b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 NCKAP5 PTPN14 SCNN1B FRAS1 ANK3 MAGI3 NBEA SIX1 KIAA1217	4.00e-07	191	281	10	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	droplet-Lung-30m-Mesenchymal\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGSF10 AEBP1 SCN3A CHRDL1 BICC1 VLDLR COL6A3 RBP1 GRIA1 FAIM2	4.19e-07	192	281	10	5d5bec238b196f0b3e727fd94f078d6ae524cb01
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	CPAMD8 NCKAP5 PTPN14 SCNN1B FRAS1 ANK3 MAGI3 NBEA SIX1 KIAA1217	4.40e-07	193	281	10	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	WNT4 PTPN14 NAV3 NOTCH3 FOXC2 CHMP4C COL6A3 SEMA5A KIAA1217 FAIM2	4.40e-07	193	281	10	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D LGR4 TRPM3 BICC1 FRAS1 ANK3 COBLL1 SLC3A1 MLXIPL LRBA	4.40e-07	193	281	10	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 NCKAP5 PTPN14 SCNN1B FRAS1 ANK3 MAGI3 NBEA SIX1 KIAA1217	4.84e-07	195	281	10	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CPAMD8 LGR4 MCM3 PFKM NPM3 TRPM3 RBP1 SEMA5A NBEA KIAA1217	4.84e-07	195	281	10	2fa0216ba493d9722324c0a9a0c59c40e72b3c4e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells-retina_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CPAMD8 LGR4 MCM3 PFKM NPM3 TRPM3 RBP1 SEMA5A NBEA KIAA1217	4.84e-07	195	281	10	06a437459717dc3c41ec343b1ec57cf910ecbdd8
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	TANC2 KIF21B RGMB NRXN2 PDZD4 ANK3 RBP1 BRSK2 CSNK1E EIF4G3	6.10e-07	200	281	10	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AEBP1 SCN3A CELF6 FRAS1 DSCAM POLR2A RBP1 ATP13A5 PTPRT	1.33e-06	169	281	9	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM3 ULK4 FRAS1 HUS1B POLR2A FRYL PTPRT MLXIPL PCNX1	1.69e-06	174	281	9	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21B AEBP1 CHRDL1 C3 FOXC2 COL6A3 CILP CDH19 FAIM2	1.69e-06	174	281	9	9c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21B AEBP1 CHRDL1 C3 FOXC2 COL6A3 CILP CDH19 FAIM2	1.69e-06	174	281	9	bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D STIM1 TRPM3 SCN3A SCNN1B ANK3 LRRC9 MOB1B	1.95e-06	177	281	9	f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CEACAM6 NCKAP5 PTPN14 SCNN1B MYRF FRAS1 DSCAM MAGI3 SEMA5A	2.14e-06	179	281	9	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	Epithelial-basal_cell\|World / Lineage, Cell type, age group and donor	LGR4 WNT4 ANKRD18B PTPN14 PKP1 FRAS1 ANK3 LAMA5 KIAA1217	2.14e-06	179	281	9	d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 NCKAP5 PTPN14 SCNN1B CX3CL1 FRAS1 MAGI3 NBEA KIAA1217	2.45e-06	182	281	9	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO7B AQP7B NCKAP5 TRPM3 D2HGDH SLC12A6 AQP7 SLC3A1 MLXIPL	2.68e-06	184	281	9	9434731f651820b05335085582960f08fbf895de
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	NCKAP5 PTPN14 SCNN1B CPLANE1 MYRF DSCAM COBLL1 MAGI3 SEMA5A	2.80e-06	185	281	9	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 CPAMD8 PDE4D SCN3A SCNN1B MAP4K3 COBLL1 MAGI3 MOB1B	2.80e-06	185	281	9	3d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	CPAMD8 PDE4D ACACA SCNN1B ANK3 COBLL1 MAGI3 KIAA1217 LRBA	3.06e-06	187	281	9	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CPAMD8 NCKAP5 MYRF FRAS1 LAMA5 MAGI3 SEMA5A MLXIPL KIAA1217	3.06e-06	187	281	9	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 PDE4D TRPM3 SCNN1B ALAS1 FRAS1 ANK3 COBLL1 MOB1B	3.20e-06	188	281	9	e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D GREB1L TRPM3 SCN3A SCNN1B FRAS1 ANK3 COBLL1	3.34e-06	189	281	9	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	facs-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AEBP1 SCN3A CHRDL1 C3 BICC1 VLDLR COL6A3 RBP1 FAIM2	3.34e-06	189	281	9	bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D GREB1L TRPM3 SCNN1B FRAS1 ANK3 SLC44A1 MOB1B	3.34e-06	189	281	9	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AEBP1 SCN3A CHRDL1 C3 BICC1 VLDLR COL6A3 RBP1 FAIM2	3.34e-06	189	281	9	40cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D GREB1L TRPM3 SCN3A SCNN1B ANK3 SLC44A1 MOB1B	3.34e-06	189	281	9	532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 PDE4D TRPM3 SCNN1B ALAS1 FRAS1 ANK3 COBLL1 MOB1B	3.49e-06	190	281	9	11d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IGSF10 AEBP1 NAV3 CHRDL1 C3 BICC1 VLDLR COL6A3 CILP	3.80e-06	192	281	9	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D GREB1L TRPM3 SCN3A SCNN1B MYRF ANK3 COBLL1	3.80e-06	192	281	9	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 PDE4D TRPM3 SCNN1B ALAS1 FRAS1 COBLL1 SLC44A1 MOB1B	3.80e-06	192	281	9	fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 EMILIN2 WNT4 C3 BICC1 VLDLR SEMA5A CCNG1 SLC44A1	3.80e-06	192	281	9	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TANC2 PDE4D PICALM ATG7 MAP4K3 AMBRA1 PCNX1 LRBA EIF4G3	3.96e-06	193	281	9	779276e775cb2492e8dd36436295a536084a6415
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D GREB1L TRPM3 SCN3A SCNN1B FRAS1 ANK3 COBLL1	4.13e-06	194	281	9	4d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D LGR4 TRPM3 BICC1 FRAS1 ANK3 COBLL1 SLC3A1 LRBA	4.13e-06	194	281	9	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	CEACAM6 NCKAP5 BCLAF3 UBR5 SCNN1B LAMA5 RDX SPATA20 HGS	4.13e-06	194	281	9	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	CEACAM6 NCKAP5 BCLAF3 UBR5 SCNN1B LAMA5 RDX SPATA20 HGS	4.13e-06	194	281	9	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	TANC2 PDE4D ACACA ANK3 MAP4K3 AMBRA1 MAGI3 LRBA MBD5	4.49e-06	196	281	9	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	LGR4 ANKRD18B PTPN14 PKP1 CX3CL1 FRAS1 LAMA5 SIX1 KIAA1217	4.68e-06	197	281	9	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ITIH1 AEBP1 CX3CL1 NOTCH3 FOXC2 SGCA BRSK2 LAMA5 KANK3	4.68e-06	197	281	9	0f9836554ace3f9d155ebafdd719aa26466ca44e
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EFCAB12 ULK4 CPLANE1 CFAP47 RPGRIP1L TOGARAM2 PTPRT LRRC9 CFAP74	4.68e-06	197	281	9	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	PDE4B DOCK11 EMILIN2 ARHGAP22 TAOK3 SIGLEC10 ARHGAP25 DMXL2 ATG7	4.68e-06	197	281	9	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ITIH1 AEBP1 CX3CL1 NOTCH3 FOXC2 SGCA BRSK2 LAMA5 KANK3	4.68e-06	197	281	9	71367bebc23d0e81f60f780d6b0ab3a1783ac014
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CPAMD8 NCKAP5 PTPN14 SCNN1B NOTCH3 FRAS1 ANK3 MAGI3 KIAA1217	4.88e-06	198	281	9	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CPAMD8 NCKAP5 PTPN14 SCNN1B NOTCH3 FRAS1 ANK3 MAGI3 KIAA1217	4.88e-06	198	281	9	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	TANC2 PDE4D ACACA ANK3 MAP4K3 AMBRA1 MAGI3 LRBA MBD5	4.88e-06	198	281	9	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OBSCN NCKAP5 WNT4 KLHL29 PKP1 FRAS1 LAMA5 SEMA5A PTPRT	5.08e-06	199	281	9	94a7867e800df352731796de8c24cba133c29622
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGSF10 NRXN2 AEBP1 CHRDL1 C3 BICC1 COL6A3 RBP1 FAIM2	5.29e-06	200	281	9	8d2ceb2080c67b20f452eeca605aa27a58033c04
ToppCell	367C-Fibroblasts-Fibroblast-E\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGSF10 AEBP1 CHRDL1 C3 BICC1 COL6A3 CILP RBP1 FAIM2	5.29e-06	200	281	9	ddfbc004e7bd2fd3f11f046ed8fc049277160547
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	IGSF10 NRXN2 AEBP1 CHRDL1 C3 BICC1 COL6A3 RBP1 FAIM2	5.29e-06	200	281	9	c338a08c1605527ab9aaf62ea151a19e8469dc6d
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGSF10 NRXN2 AEBP1 CHRDL1 C3 BICC1 COL6A3 RBP1 FAIM2	5.29e-06	200	281	9	0b2614b8513693dd508c9003699049efd9abac52
ToppCell	367C-Fibroblasts-Fibroblast-E-\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGSF10 AEBP1 CHRDL1 C3 BICC1 COL6A3 CILP RBP1 FAIM2	5.29e-06	200	281	9	57b9d6aa2265ab178a5886f36ecc66115bd382a8
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	KIF21B NRXN2 MAD1L1 PDZD4 ANK3 RBP1 GRIA1 NBEA PTPRT	5.29e-06	200	281	9	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B PDE4B ACACA STRADA POLR2A HAUS5 GPATCH2 MBD5	7.51e-06	158	281	8	1d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CHRDL1 PDZD4 FOXC2 SGCA NBEA SIX1 SLC18A2 SNTB2	8.62e-06	161	281	8	9703b7e67d9fadb6129cad166bd01be915042e44
ToppCell	facs-Marrow-KLS-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APC2 WNT4 EMSY COL6A3 DSCAM SEMA5A CD7 MOB1B	9.87e-06	164	281	8	d2b5f51af7fcffddebe997ee302bacbd85d76852
ToppCell	Children_(3_yrs)-Epithelial-basal_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LGR4 ANKRD18B PTPN14 PKP1 FRAS1 ANK3 LAMA5 KIAA1217	1.79e-05	178	281	8	fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR52 TRPM3 SCNN1B ULK4 FRAS1 HUS1B MLXIPL PCNX1	1.79e-05	178	281	8	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL29 AEBP1 C3 MYRF BICC1 PDZD4 PTPRT CDC20	1.79e-05	178	281	8	c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM4 PTPN14 FRAS1 ANK3 DSCAM LAMA5 MAGI3 KIAA1217	1.86e-05	179	281	8	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WNT4 CHRDL1 VLDLR CILP RBP1 GRIA1 PLCD4 FAIM2	1.94e-05	180	281	8	e9785ac2806103f725f5a5208495826354ec6e22
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NCKAP5 SCNN1B NOTCH3 FRAS1 MAGI3 NBEA SIX1 KIAA1217	1.94e-05	180	281	8	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSS1 CUL7 EMSY PTPN14 COL6A3 LRRC9 CCNG1 CFAP74	2.02e-05	181	281	8	41969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRPM3 SCNN1B MYRF FRAS1 MAGI3 SEMA5A HEATR5A KIFC2	2.02e-05	181	281	8	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSS1 CUL7 EMSY PTPN14 COL6A3 LRRC9 CCNG1 CFAP74	2.02e-05	181	281	8	3f50e61dc2a52d71a5801584617607e6246adcf2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 LGR4 BRINP1 KLHL29 PTPN14 BICC1 FRAS1 COBLL1	2.02e-05	181	281	8	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D TRPM3 SCNN1B FRAS1 ANK3 COBLL1 SLC44A1 MOB1B	2.02e-05	181	281	8	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 LGR4 BRINP1 KLHL29 PTPN14 BICC1 FRAS1 COBLL1	2.10e-05	182	281	8	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK11 CEACAM6 NCKAP5 SCNN1B MYRF DSCAM LAMA5 KANK3	2.27e-05	184	281	8	c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CEACAM6 NCKAP5 PTPN14 SCNN1B MYRF LAMA5 MAGI3 SEMA5A	2.27e-05	184	281	8	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CEACAM6 NCKAP5 SCNN1B MYRF AGAP3 DSCAM LAMA5 NCOR2	2.27e-05	184	281	8	cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK11 CEACAM6 NCKAP5 SCNN1B MYRF DSCAM LAMA5 KANK3	2.27e-05	184	281	8	1ed558a88215b248431c524ea16f13d9022ae98c
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CEACAM6 NCKAP5 SCNN1B MYRF AGAP3 DSCAM LAMA5 NCOR2	2.27e-05	184	281	8	bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK11 MYO7B TRPM3 VPS13A BICC1 SEMA5A SLC3A1 MLXIPL	2.27e-05	184	281	8	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CEACAM6 NCKAP5 PTPN14 SCNN1B MYRF LAMA5 MAGI3 SEMA5A	2.27e-05	184	281	8	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CEACAM6 NCKAP5 PTPN14 SCNN1B MYRF LAMA5 MAGI3 SEMA5A	2.36e-05	185	281	8	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 PDE4D ACACA PTPN14 SCNN1B ANK3 MAGI3 KIAA1217	2.36e-05	185	281	8	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 PDE4D GREB1L TRPM3 SCNN1B FRAS1 ANK3 COBLL1	2.36e-05	185	281	8	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D GREB1L TRPM3 SCNN1B FRAS1 ANK3 SLC44A1 MOB1B	2.36e-05	185	281	8	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGSF10 AEBP1 CHRDL1 BICC1 COL6A3 CILP PRKAG3 BRSK1	2.36e-05	185	281	8	355b03c7ea438681e11a2b872c798c9ea26e1486
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO7B AQP7B NCKAP5 TRPM3 D2HGDH SLC12A6 AQP7 MLXIPL	2.45e-05	186	281	8	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	AEBP1 KCND3 C3 COL6A3 CILP RBP5 RBP1 SEMA5A	2.55e-05	187	281	8	e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHST5 AEBP1 SLC17A7 CHRDL1 NOTCH3 RBP1 GRIA1 FAIM2	2.55e-05	187	281	8	976b74d081b7fba8620768613cc26f9262cd7b16
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	CPAMD8 NCKAP5 SCNN1B NOTCH3 FRAS1 NBEA SIX1 KIAA1217	2.55e-05	187	281	8	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
Drug	apple polyphenol extract	CHST5 CHST6 AEBP1 NFKB2 AQP7 CTNNB1	1.28e-06	30	272	6	ctd:C526219
Drug	4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid	PDE4A PDE4B PDE4D	1.69e-06	3	272	3	DB08299
Drug	rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; PC3; HT_HG-U133A	KLHL29 TAS2R1 KCND3 LIPG NFKB2 NAV3 SLC17A7 DSCAM HAUS5 ZNF711 CSNK1E TCTN2	4.28e-06	195	272	12	5980_DN
Drug	Piclamilast	PDE4A PDE4B PDE4D	6.69e-06	4	272	3	DB01791
Drug	D-22888	PDE4A PDE4B PDE4D	1.66e-05	5	272	3	CID000197714
Drug	Ibudilast	PDE4A PDE4B PDE4D	1.66e-05	5	272	3	DB05266
Drug	1,7-naphthyridine	PDE4A PDE4B PDE4D	1.66e-05	5	272	3	CID000009209
Drug	Adenosine monophosphate	PDE4B PDE4D ACSS1 PRKAB1	1.81e-05	14	272	4	DB00131
Drug	Antimycin A [1397-94-0]; Up 200; 7.2uM; PC3; HT_HG-U133A	KIF21B PDE4A IGSF6 PDE4D RYR1 PYHIN1 SLC17A7 ARHGAP25 BRSK2 MED1 SLC44A1	2.79e-05	198	272	11	5053_UP
Drug	chlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A	RYR1 TRPM3 VNN1 PKP1 CILP COBLL1 SEMA5A NCOR2 BAZ2A KCTD20 SLC12A7	2.93e-05	199	272	11	2677_UP
Drug	Mesalamine [89-57-6]; Down 200; 26.2uM; PC3; HT_HG-U133A	CEACAM6 TUBGCP2 NPM3 TMEM161A TULP4 NUP210 VPS13A NAV3 AMBRA1 PPFIA3 PRKAB1	2.93e-05	199	272	11	5888_DN
Drug	Hippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; PC3; HT_HG-U133A	CUL7 GREB1L STIM1 NFKB2 C3 CPLANE1 NOTCH3 VLDLR PPFIA3 RAB3GAP1 BAZ2A	3.06e-05	200	272	11	3682_DN
Drug	Ketotifen	PDE4A PDE4B PDE4D	5.70e-05	7	272	3	DB00920
Drug	Iloprost	PDE4A PDE4B PDE4D	5.70e-05	7	272	3	DB01088
Drug	Dyphylline	PDE4A PDE4B PDE4D	9.03e-05	8	272	3	DB00651
Drug	KF18280	PDE4A PDE4B PDE4D	9.03e-05	8	272	3	CID003071941
Drug	troglitazone; Up 200; 10uM; MCF7; HT_HG-U133A	PDE4B EPPK1 CUL7 NPM3 SLC17A7 NCOR2 BAZ2A ASPH PCNX1 FAIM2	1.20e-04	194	272	10	5229_UP
Drug	Carbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A	IGSF6 TUBGCP2 CUL7 NPM3 TMEM161A NFKB2 HAUS5 RALGAPB AMBRA1 SLC44A1	1.25e-04	195	272	10	5399_DN
Drug	Mefenamic acid [61-68-7]; Down 200; 16.6uM; PC3; HT_HG-U133A	EPPK1 PTPN14 VPS13A PKP1 RPRD2 PLK3 PPFIA3 MED1 BAZ2A TCTN2	1.31e-04	196	272	10	1821_DN
Drug	trequinsin	PDE4A PDE4B PDE4D	1.34e-04	9	272	3	ctd:C035964
Drug	L-826,141	PDE4A PDE4B PDE4D	1.34e-04	9	272	3	ctd:C459562
Drug	Cetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; HL60; HT_HG-U133A	MYBPH PYCR3 FOXC2 ANK3 CILP COBLL1 PPFIA3 SLC22A18AS SLC12A7 SNTB2	1.36e-04	197	272	10	2468_UP
Drug	Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; PC3; HT_HG-U133A	KIF21B PDE4B PKP1 SLC17A7 COBLL1 SLC22A18AS NCOR2 CD7 BAZ2A CEP152	1.42e-04	198	272	10	6651_UP
Drug	Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; HL60; HT_HG-U133A	MYBPH CEACAM6 CUL7 PKP1 PYCR3 ANK3 CILP PPFIA3 SLC22A18AS PCNX1	1.42e-04	198	272	10	2492_UP
Drug	Denatonium benzoate [3734-33-6]; Down 200; 9uM; MCF7; HT_HG-U133A	CEACAM6 NFKB2 RPGRIP1L DSCAM COBLL1 HAUS5 AMBRA1 SIAH1 PPFIA3 CSNK1E	1.42e-04	198	272	10	6502_DN
Drug	Ceforanide [60925-61-3]; Up 200; 7.6uM; PC3; HT_HG-U133A	NPM3 TRPM3 KCND3 NFKB2 SCNN1B CPLANE1 BICC1 NOTCH3 SLC3A1 SLC18A2	1.42e-04	198	272	10	6751_UP
Drug	V11294 Analogue 5f	PDE4B PDE4D	1.42e-04	2	272	2	CID011214587
Drug	V11294 Analogue 5t	PDE4B PDE4D	1.42e-04	2	272	2	CID011226695
Drug	V11294 Analogue 5e	PDE4B PDE4D	1.42e-04	2	272	2	CID011443441
Drug	V11294 Analogue 5n	PDE4B PDE4D	1.42e-04	2	272	2	CID011238279
Drug	V11294 Analogue 5p	PDE4B PDE4D	1.42e-04	2	272	2	CID011478659
Drug	poly-N-acetyllactosamine	CHST5 CHST6	1.42e-04	2	272	2	ctd:C037199
Drug	V11294 Analogue 5o	PDE4B PDE4D	1.42e-04	2	272	2	CID011249748
Drug	V11294 Analogue 5c	PDE4B PDE4D	1.42e-04	2	272	2	CID011179896
Drug	V11294 Analogue 5b	PDE4B PDE4D	1.42e-04	2	272	2	CID011443760
Drug	Cis-4-Cyano-4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]Cyclohexanecarboxylic Acid	PDE4B PDE4D	1.42e-04	2	272	2	DB03849
Drug	T-2585.HCl	PDE4B PDE4D	1.42e-04	2	272	2	CID006918355
Drug	2,3,5-tri-O-benzyl-D-arabinofuranose	PFKL PFKM	1.42e-04	2	272	2	CID000255457
Drug	V11294 Analogue 5m	PDE4B PDE4D	1.42e-04	2	272	2	CID011477773
Drug	V11294 Analogue 8a	PDE4B PDE4D	1.42e-04	2	272	2	CID011442865
Drug	V11294 Analogue 5q	PDE4B PDE4D	1.42e-04	2	272	2	CID011318772
Drug	V11294 Analogue 5h	PDE4B PDE4D	1.42e-04	2	272	2	CID011306698
Drug	3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester	PDE4B PDE4D	1.42e-04	2	272	2	DB01959
Drug	4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]-2-Pyrrolidinone	PDE4B PDE4D	1.42e-04	2	272	2	DB01954
Drug	M 98	PDE4B PDE4D	1.42e-04	2	272	2	CID006420180
Drug	V11294 Analogue 5i	PDE4B PDE4D	1.42e-04	2	272	2	CID011376249
Drug	apiol	SAGE1 SPEN	1.42e-04	2	272	2	CID000010659
Drug	V11294 Analogue 5d	PDE4B PDE4D	1.42e-04	2	272	2	CID011283750
Drug	3-cyclopentyloxy-4-methoxybenzoic acid	PDE4B PDE4D	1.42e-04	2	272	2	CID002779323
Drug	V11294 Analogue 5v	PDE4B PDE4D	1.42e-04	2	272	2	CID011375325
Drug	3-cyclopentyloxy-4-methoxybenzaldehyde	PDE4B PDE4D	1.42e-04	2	272	2	CID002735893
Drug	Np-V	PDE4B PDE4D	1.42e-04	2	272	2	CID009999276
Drug	(S)-Rolipram	PDE4B PDE4D	1.42e-04	2	272	2	DB03606
Drug	1-((5-(1-aminoethyl)-2-(8-methoxy-2-(triflurormethyl)-5-quinolinyl)-4-oxazolyl) carbonyl)-4-((cyclopropylcarbonyl)amino)proline ethyl ester	PDE4B PDE4D	1.42e-04	2	272	2	ctd:C554440
Drug	V11294 Analogue 5r	PDE4B PDE4D	1.42e-04	2	272	2	CID011168555
Drug	V11294 Analogue 5j	PDE4B PDE4D	1.42e-04	2	272	2	CID011433797
Drug	V11294 Analogue 5a	PDE4B PDE4D	1.42e-04	2	272	2	CID011386897
Drug	V11294 Analogue 5k	PDE4B PDE4D	1.42e-04	2	272	2	CID011456440
Drug	(R)-Rolipram	PDE4B PDE4D	1.42e-04	2	272	2	DB04149
Drug	(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one	PDE4A PDE4D	1.42e-04	2	272	2	DB06842
Disease	primary ovarian insufficiency (implicated_via_orthology)	USP17L21 USP17L20 USP17L19 NPM3 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	1.83e-16	46	270	13	DOID:5426 (implicated_via_orthology)
Disease	congenital heart disease (implicated_via_orthology)	USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L13 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22 USP17L15	1.50e-12	69	270	12	DOID:1682 (implicated_via_orthology)
Disease	ciliopathy (implicated_via_orthology)	TOGARAM1 MAP4K2 RPGRIP1L MAP4K3 TOGARAM2	3.13e-05	40	270	5	DOID:0060340 (implicated_via_orthology)
Disease	Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 1	ATP8A2 VLDLR	8.34e-05	2	270	2	C4551552
Disease	MICROCEPHALY 4, PRIMARY, AUTOSOMAL RECESSIVE	KNL1 CEP152	8.34e-05	2	270	2	C1858516
Disease	autism spectrum disorder (implicated_via_orthology)	BRINP1 TAOK3 NRXN2 PKP1 DSCAM NBEA CTNNB1 LRBA	8.34e-05	152	270	8	DOID:0060041 (implicated_via_orthology)
Disease	Parkinson's disease (implicated_via_orthology)	SYNJ1 VPS13A SLC17A7 ATG7 NSF ATP13A5 SLC18A2 EIF4G3	1.05e-04	157	270	8	DOID:14330 (implicated_via_orthology)
Disease	1,5 anhydroglucitol measurement	NCKAP5 MGAM2 PCDHAC1 RAB3GAP1	1.36e-04	29	270	4	EFO_0008009
Disease	Bipolar Disorder	PDE4A PDE4B PFKL ITIH1 BID SLC17A7 ULK4 SLC12A6 ANK3 DSCAM GRIA1 SLC18A2 CSNK1E MBD5	1.43e-04	477	270	14	C0005586
Disease	anxiety disorder	PDE4B KCNK9 OR8A1 MGAM2	1.56e-04	30	270	4	EFO_0006788
Disease	Autistic Disorder	PDE4A PDE4B CUL7 NRXN2 VLDLR BRSK2 GRIA1 SEMA5A NBEA REEP3	1.59e-04	261	270	10	C0004352
Disease	serine/threonine-protein kinase BRSK2 measurement	BRSK2 BRSK1	2.49e-04	3	270	2	EFO_0803063
Disease	attention deficit hyperactivity disorder, mental or behavioural disorder	STIM1 MAD1L1	2.49e-04	3	270	2	EFO_0000677, EFO_0003888
Disease	Intellectual Disability	TANC2 ZC3H14 ATP8A2 APC2 SHROOM4 NRXN2 TRPM3 SCN3A PHIP NSF BRSK2 GRIA1 NBEA	2.69e-04	447	270	13	C3714756
Disease	resting heart rate	PDE4B EPPK1 CEP85L KLHL42 MYRF GPATCH2 ASPH	4.62e-04	149	270	7	EFO_0004351
Disease	cerebellar ataxia, mental retardation and dysequlibrium syndrome (is_implicated_in)	ATP8A2 VLDLR	4.94e-04	4	270	2	DOID:0050997 (is_implicated_in)
Disease	glycogen storage disease (implicated_via_orthology)	PFKL PFKM	4.94e-04	4	270	2	DOID:2747 (implicated_via_orthology)
Disease	semaphorin-5A measurement	TAS2R1 SEMA5A	4.94e-04	4	270	2	EFO_0021864
Disease	Ciliopathies	CDH23 SCNN1B CPLANE1 RPGRIP1L BBS12 TCTN2	5.37e-04	110	270	6	C4277690
Disease	free cholesterol to total lipids in large LDL percentage	MYRF COBLL1 PRKAG3 MLXIPL KANK3	5.95e-04	74	270	5	EFO_0022280
Disease	Polydactyly	CPLANE1 FRAS1 RPGRIP1L KIF3A BBS12 TCTN2	7.44e-04	117	270	6	C0152427
Disease	fatty acid measurement	ATP8A2 GREB1L TMEM161A LIPG MYRF MAP4K2 NSF COBLL1 GRIA1 PRKAG3 MLXIPL KANK3	7.47e-04	436	270	12	EFO_0005110
Disease	monounsaturated fatty acids; 16:1, 18:1 measurement	LIPG MYRF COBLL1 PRKAG3 MLXIPL	7.57e-04	78	270	5	EFO_0022187
Disease	Self-injurious behavior	BRINP1 SPTBN5 AEBP1 NIPBL DSCAM	7.57e-04	78	270	5	HP_0100716
Disease	Familial aplasia of the vermis	CPLANE1 RPGRIP1L TCTN2	7.70e-04	20	270	3	cv:C0431399
Disease	Dysequilibrium syndrome	ATP8A2 VLDLR	8.19e-04	5	270	2	C0394006
Disease	Seizures	TANC2 APC2 TRPM3 SLC17A7 AP3D1 NOTCH3 NSF NBEA	9.45e-04	218	270	8	C0036572
Disease	lipid measurement, high density lipoprotein cholesterol measurement	LIPG ANKDD1B MYRF KNL1 COBLL1 REEP3 PRKAG3 NCOR2 MLXIPL MAPKBP1	9.94e-04	330	270	10	EFO_0004529, EFO_0004612
Disease	high density lipoprotein particle size measurement	AHCYL1 LIPG KNL1 COBLL1 REEP3 NCOR2 MLXIPL	1.01e-03	170	270	7	EFO_0008592
Disease	Autosomal Recessive Primary Microcephaly	ANKLE2 KNL1 CEP152	1.03e-03	22	270	3	C3711387
Disease	triacylglycerol 58:9 measurement	NFKB2 MYRF PTPRT	1.03e-03	22	270	3	EFO_0010443
Disease	Primary microcephaly	KNL1 CEP152 CTNNB1	1.03e-03	22	270	3	C0431350
Disease	cholesteryl esters to total lipids in IDL percentage	LIPG COBLL1 PRKAG3 MLXIPL	1.13e-03	50	270	4	EFO_0022247
Disease	bipolar disorder, schizophrenia, schizoaffective disorder	ITIH1 MAD1L1	1.22e-03	6	270	2	EFO_0005411, MONDO_0004985, MONDO_0005090
Disease	triglycerides to total lipids in large LDL percentage	ANKDD1B COBLL1 PRKAG3 MLXIPL	1.22e-03	51	270	4	EFO_0022331
Disease	polyunsaturated fatty acids to monounsaturated fatty acids ratio	MYRF COBLL1 PRKAG3 MLXIPL	1.22e-03	51	270	4	EFO_0022302
Disease	cleft lip	TANC2 ATP8A2 CCDC168 KCNK9 BICC1 MGAM2 GRIA1 SEMA5A NCOR2	1.30e-03	284	270	9	EFO_0003959
Disease	sexual dimorphism measurement	EPPK1 RGPD1 LGR4 KLHL29 SPTBN5 LIPG CASKIN1 ANKDD1B ULK4 MYRF PHIP AP3D1 COBLL1 POLR2A FRYL NCOR2 MLXIPL KANK3 CTNNB1 MAPKBP1 FAIM2	1.38e-03	1106	270	21	EFO_0021796
Disease	Global developmental delay	APC2 TRPM3 NSF POLR2A BRSK2 NBEA	1.44e-03	133	270	6	C0557874
Disease	Bone Diseases, Developmental	NIPBL SLC26A2 KIF3A	1.88e-03	27	270	3	C0005941
Disease	cholesteryl ester 14:0 measurement	SCN3A NAV3 MYRF	1.88e-03	27	270	3	EFO_0010340
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	LIPG ANKDD1B COBLL1 REEP3 PRKAG3 MLXIPL	2.16e-03	144	270	6	EFO_0004611, EFO_0020943
Disease	cholesterol to total lipids in IDL percentage	ANKDD1B COBLL1 PRKAG3 MLXIPL	2.24e-03	60	270	4	EFO_0022233
Disease	PROSTATE CANCER, HEREDITARY, 1	ATAT1 EMSY MAD1L1 KNL1	2.24e-03	60	270	4	C4722327
Disease	neurodegenerative disease (implicated_via_orthology)	ATAT1 NFKB2 SCNN1B SLC17A7 GRIA1 PRKAG3	2.24e-03	145	270	6	DOID:1289 (implicated_via_orthology)
Disease	Unilateral agenesis of kidney	GREB1L FRAS1	2.25e-03	8	270	2	C0266294
Disease	sarcoma (is_implicated_in)	KNL1 CCNG1	2.25e-03	8	270	2	DOID:1115 (is_implicated_in)
Disease	pulse pressure measurement	PFKM ITIH1 KLHL29 TRPM3 KLHL42 ULK4 MAP4K2 AP3D1 BICC1 NOTCH3 TCEA2 COL6A3 DSCAM ATG7 COBLL1 PCDHAC1 LAMA5 RNF213 NBEA HEATR5A FRYL KIAA1217 MBD5 PBX3	2.32e-03	1392	270	24	EFO_0005763
Disease	Bilateral Wilms Tumor	COL6A3 SIX1 CTNNB1	2.32e-03	29	270	3	C2930471
Disease	atrial fibrillation	CEP85L TAB2 STIM1 KCND3 POLR2A REEP3 NCOR2 MOB1B MBD5 SPEN	2.36e-03	371	270	10	EFO_0000275
Disease	gastroesophageal reflux disease	PDE4B MAD1L1 NAV3 PTPRT PBX3	2.40e-03	101	270	5	EFO_0003948
Disease	free cholesterol in very large HDL measurement	ANKDD1B COBLL1 REEP3 MLXIPL	2.52e-03	62	270	4	EFO_0022273
Disease	Familial aplasia of the vermis	CPLANE1 RPGRIP1L TCTN2	2.56e-03	30	270	3	C0431399
Disease	free cholesterol measurement, high density lipoprotein cholesterol measurement	LIPG MYRF KNL1 COBLL1 REEP3 PRKAG3 NCOR2 MLXIPL MAPKBP1	2.62e-03	315	270	9	EFO_0004612, EFO_0008591
Disease	total cholesterol measurement, high density lipoprotein cholesterol measurement	AHCYL1 LIPG MYRF COBLL1 REEP3 PRKAG3 NCOR2 MLXIPL MAPKBP1	2.62e-03	315	270	9	EFO_0004574, EFO_0004612
Disease	cholesterol to total lipids in medium VLDL percentage	MYRF COBLL1 PRKAG3 MLXIPL	2.67e-03	63	270	4	EFO_0022239
Disease	cholesteryl esters to total lipids in medium VLDL percentage	MYRF COBLL1 PRKAG3 MLXIPL	2.83e-03	64	270	4	EFO_0022253
Disease	triglycerides in small LDL measurement	COBLL1 PRKAG3 MLXIPL KANK3	3.00e-03	65	270	4	EFO_0022323
Disease	Adenocarcinoma of lung (disorder)	NPM3 TAOK3 EIF2B4 RAF1 CSNK1E CTNNB1 PSKH2	3.00e-03	206	270	7	C0152013
Disease	thyroid stimulating hormone measurement	PDE4B PDE4D WNT4 PTPN14 SCNN1B TCEA2 CRTC3 NSF KIAA1217	3.09e-03	323	270	9	EFO_0004748
Disease	microcephaly (implicated_via_orthology)	ANKLE2 MAD1L1 MAPKBP1	3.09e-03	32	270	3	DOID:10907 (implicated_via_orthology)
Disease	platelet crit	PDE4A ZFPM1 STK35 BID KLHL29 TULP4 MAD1L1 NAV3 CHRDL1 RPRD2 ARHGAP25 NOTCH3 VLDLR RBP5 LAMA5 PRKAB1 SLC41A1 SLC12A7	3.13e-03	952	270	18	EFO_0007985
Disease	total lipids in very large HDL measurement	LIPG ANKDD1B COBLL1 MLXIPL	3.17e-03	66	270	4	EFO_0022312
Disease	phospholipids in very large HDL measurement	LIPG ANKDD1B COBLL1 MLXIPL	3.17e-03	66	270	4	EFO_0022298
Disease	Craniofacial Abnormalities	NIPBL FOXC2 SLC26A2 SIX1 KIF3A CTNNB1	3.22e-03	156	270	6	C0376634
Disease	hemoglobin A1 measurement	PFKL PFKM TAOK3 TULP4 MAD1L1 VPS13A ARHGAP25 MAP4K2 NSF COBLL1 MLXIPL SLC12A7	3.24e-03	520	270	12	EFO_0007629
Disease	cholesterol to total lipids in very small VLDL percentage	COBLL1 REEP3 PRKAG3 MLXIPL	3.34e-03	67	270	4	EFO_0022245
Disease	Schizophrenia	PDE4A PDE4B PDE4D ITIH1 BID NRXN2 MAD1L1 SLC17A7 ULK4 VLDLR ANK3 RBP1 AMBRA1 GRIA1 SLC18A2 CSNK1E CTNNB1	3.38e-03	883	270	17	C0036341
Disease	Disorder of eye	CDH23 CPLANE1 FRAS1 RPGRIP1L PRPF8 BBS12 TCTN2	3.51e-03	212	270	7	C0015397
Disease	fatty acid measurement, linoleic acid measurement	MYRF COBLL1 PRKAG3 MLXIPL	3.53e-03	68	270	4	EFO_0005110, EFO_0006807
Disease	triglycerides to phosphoglycerides ratio	COBLL1 PRKAG3 MLXIPL KANK3	3.53e-03	68	270	4	EFO_0022327
Disease	Meckel-Gruber syndrome	RPGRIP1L TCTN2	3.58e-03	10	270	2	cv:C0265215
Disease	cystic kidney disease (implicated_via_orthology)	BICC1 LAMA5	3.58e-03	10	270	2	DOID:2975 (implicated_via_orthology)
Disease	triglycerides to total lipids in very small VLDL percentage	MYRF COBLL1 PRKAG3 MLXIPL	3.72e-03	69	270	4	EFO_0022341
Disease	Prostate cancer, familial	ATAT1 EMSY MAD1L1 KNL1	3.72e-03	69	270	4	C2931456
Disease	HbA1c measurement	CPAMD8 PFKL PFKM KLHL29 AEBP1 EIF2B4 MAD1L1 VPS13A ARHGAP25 MAP4K2 RAF1 NSF COBLL1 MLXIPL	3.98e-03	675	270	14	EFO_0004541
Disease	malignant epithelial tumor of ovary	WNT4 CHMP4C NSF	3.99e-03	35	270	3	MONDO_0018364
Disease	phosphatidylcholine 38:2 measurement	STK35 LIPG MYRF	3.99e-03	35	270	3	EFO_0010384
Disease	cholesteryl esters to total lipids in very small VLDL percentage	COBLL1 REEP3 PRKAG3 MLXIPL	4.12e-03	71	270	4	EFO_0022259
Disease	trait in response to apixaban	MROH5 BRINP1 C3 SYNE3 CSNK1E	4.19e-03	115	270	5	OBA_2050328
Disease	Nephroblastoma	COL6A3 SIX1 CTNNB1	4.33e-03	36	270	3	C0027708
Disease	triglycerides to total lipids in small HDL percentage	COBLL1 PRKAG3 MLXIPL KANK3	4.33e-03	72	270	4	EFO_0022336
Disease	atopic eczema, childhood onset asthma, atopic march	EMSY KIF3A	4.34e-03	11	270	2	EFO_0000274, EFO_0007755, MONDO_0005405
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	GREB1L EPHA10	4.34e-03	11	270	2	DOID:0050564 (is_implicated_in)
Disease	invasive ductal carcinoma (is_implicated_in)	UBR5 CSNK1E	4.34e-03	11	270	2	DOID:3008 (is_implicated_in)
Disease	uric acid measurement	NRXN2 SESN2 RFT1 MAP4K2 BICC1 FRAS1 DSCAM COBLL1 GPATCH2 REEP3 MLXIPL SLC41A1 FAIM2	4.35e-03	610	270	13	EFO_0004761
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	MAP4K2 TCEA2 COBLL1 PRKAG3 MLXIPL KANK3	4.36e-03	166	270	6	EFO_0004530, EFO_0004611
Disease	cholesteryl esters to total lipids in medium LDL percentage	LIPG COBLL1 MLXIPL	4.68e-03	37	270	3	EFO_0022252
Disease	Congenital disorder of glycosylation	RFT1 COG4 COG8	5.05e-03	38	270	3	cv:C0282577
Disease	polychlorinated biphenyls measurement, gestational serum measurement	NCKAP5 BICC1	5.18e-03	12	270	2	EFO_0007042, EFO_0007964
Disease	anxiety disorder, stress-related disorder	PDE4B PTPRT	5.18e-03	12	270	2	EFO_0006788, EFO_0010098
Disease	Congenital muscular dystrophy	RYR1 GMPPB	5.18e-03	12	270	2	cv:C0699743
Disease	migraine disorder	TRPM3 ANKDD1B BICC1 RNF213 AMBRA1 NBEA NCOR2 MLXIPL HAUS1	5.89e-03	357	270	9	MONDO_0005277
Disease	free cholesterol in large HDL measurement	LIPG ANKDD1B COBLL1 MLXIPL	6.02e-03	79	270	4	EFO_0022157
Disease	Common variable immunodeficiency	NFKB2 LRBA	6.09e-03	13	270	2	cv:C0009447
Disease	Autosomal Dominant Myotubular Myopathy	RYR1 STIM1	6.09e-03	13	270	2	C3661489
Disease	Centronuclear myopathy	RYR1 STIM1	6.09e-03	13	270	2	C0175709
Disease	X-linked centronuclear myopathy	RYR1 STIM1	6.09e-03	13	270	2	C0410203
Disease	microsatellite instability measurement, colorectal cancer, overall survival	GRIA1 CCNG1	6.09e-03	13	270	2	EFO_0000638, EFO_0007054, MONDO_0005575
Disease	ovary epithelial cancer (is_marker_for)	PLK3 CCNG1	6.09e-03	13	270	2	DOID:2152 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LTSEARQHREVSMGL	C2orf16	436	Q68DN1
GRTALHLSSAMANVV	AGAP3	786	Q96P47
SESLQQRVHGMALSE	EXOC3L1	441	Q86VI1
TGGSMVASLHSFQRR	ACTL10	211	Q5JWF8
TGRMDDVINISGHRL	ACSS1	546	Q9NUB1
DQLGNGHRRTESEMS	ANKLE2	781	Q86XL3
LRNMTSHSARVGSLS	CDC20	261	Q12834
SSSLQRMSVIAQLAG	ATP13A5	601	Q4VNC0
SGSQDNLTITMHRLQ	CD7	91	P09564
NLTITMHRLQLSDTG	CD7	96	P09564
SLQRAREQHESIVMG	CEP152	351	O94986
QRLLGSNSMKRHLVS	CEP152	551	O94986
DGTMRRLHEIQISTG	BRINP1	176	O60477
NHLDMSVGEALRQRT	PRKAG3	411	Q9UGI9
EDNQIRASSMLRHGL	AEBP1	396	Q8IUX7
RGVTSAVNIMHSSLQ	COG4	511	Q9H9E3
HSSQMLRAVSLGQDR	BAZ2A	1106	Q9UIF9
VSRHETMGSNISQLT	ANKRD18B	461	A2A2Z9
ILHSGSDMVQAERSG	C3	331	P01024
SLQDGLALHIRSSMS	ACACA	66	Q13085
SSRGINFRTRHLMQD	BRIX1	66	Q8TDN6
RSDRQQFLGHMRGSL	ASPH	426	Q12797
LLSQLGARMTGREHA	SLC22A18AS	191	Q8N1D0
GQRRSSVLVTHAELM	DMXL2	321	Q8TDJ6
LQQAHGGETSMRRVF	AMBRA1	981	Q9C0C7
RRHMGLQQLSSFAET	BBS12	11	Q6ZW61
MSLSRSNSREHLGGG	BICC1	796	Q9H694
NTFRIDRHMGVITAA	CDH23	1681	Q9H251
LENSHTNTEVLRNMG	CHMP4C	96	Q96CF2
EAQAAIRGLHGSRTM	CELF6	186	Q96J87
NTISVNGRSRLSHSM	COBLL1	1106	Q53SF7
SMAQQRSSLATAREH	EFCAB12	266	Q6NXP0
RQGLSHTADMQTREV	ATP8A2	216	Q9NTI2
RHSMQTEQIRLLGGF	ANKRD34A	471	Q69YU3
SLNARMARPQGSSVH	AP3D1	971	O14617
QLRSHLMAEGSRTQA	C9orf152	16	Q5JTZ5
QRTVVNVRNGMSLHD	RAF1	66	P04049
LGTSAEGAHLRARMQ	RAB3GAP1	661	Q15042
MGSQEVLGHAARLAS	RFT1	1	Q96AA3
RASLAGNRNSMVIHI	KCNK9	261	Q9NPC2
GRLTSDMIAERQGHS	LRRC9	1076	Q6ZRR7
SHGMQGRSLDTNEVT	MAP4K2	761	Q12851
MEDVNLSSGHIARVS	MORC1	781	Q86VD1
ASAELSNEGVMNHRS	RDX	496	P35241
VHNRVTLELSNGSMV	ANAPC1	591	Q9H1A4
LIESAHDNGLRMTAR	CCNG1	36	P51959
GQSSLVLGHRSIRMQ	NUP210	316	Q8TEM1
ELQASMAQHRRGALQ	PHLDB3	266	Q6NSJ2
QRGSGLSMSAARSEH	NCOR2	356	Q9Y618
RMLQTLAGVNLAGHS	PBX3	6	P40426
RQDSSLGGRARHMSS	CASKIN1	691	Q8WXD9
LGGRARHMSSSQELL	CASKIN1	696	Q8WXD9
VRAHQDTQRRTSMGG	CTNNB1	541	P35222
HGMQGRSFRSNEVTQ	MAP4K3	836	Q8IVH8
RLRSMQELSTIHIQG	KCND3	566	Q9UK17
ISRNLMQRASPHSQS	PSKH2	336	Q96QS6
LHISRGERATITTQM	FRAS1	1226	Q86XX4
LDTQLLMGNRRHSLS	FAIM2	271	Q9BWQ8
SAHLREMRETNGLLQ	MAD1L1	266	Q9Y6D9
TMSVRELNQHLRGLS	MAFG	31	O15525
SMSVRELNQHLRGLT	MAFK	31	O60675
DLMTTAARNGHVLLT	MAGI3	791	Q5TCQ9
QRTLRISHDALMANG	RPGRIP1L	296	Q68CZ1
GHSMARTTNLALETI	MGAM2	536	Q2M2H8
VRASGRTMEQFTIHL	ITIH1	136	P19827
VRITGRHQIVTMSND	NPM3	131	O75607
SGNHASMIQGIRNSR	ALAS1	336	P13196
MNVHRGSDSDRLLRQ	KCTD20	1	Q7Z5Y7
RQMSQLEEELGTAHR	PPFIA3	261	O75145
MVQASGHRRSTRGSK	AQP7P3	1	A6NL99
GRTSGAHMNAAVSLT	AQP7P3	86	A6NL99
MVQASGHRRSTRGSK	AQP7B	1	A0A075B734
AHNSATGLNRTTVTM	CEACAM6	301	P40199
AQEQRLGIRISMSHE	GMPPB	66	Q9Y5P6
IEMAQHGQRSRSISG	BRSK2	401	Q8IWQ3
HRAQMAEGGQSSIAL	BMP15	21	O95972
HLRSTIELSMQGSSG	ATXN3L	246	Q9H3M9
RRALGTASHHMSSNL	PCNX1	1801	Q96RV3
RAMGINNTHTDTTIV	P3R3URF	61	A0A087WWA1
ITIQEMLAHGARSAD	PDZD4	741	Q76G19
AQSHQRTFVLEVMGR	PFKL	196	P17858
AQSHQRTFVLEVMGR	PFKM	196	P08237
LNRELTHLSEMSRSG	PDE4A	266	P27815
RELTHLSEMSRSGNQ	PDE4B	256	Q07343
LTHLSEMSRSGNQVS	PDE4D	316	Q08499
TGTHEVQSLLMRTGS	NAV3	1391	Q8IVL0
AGRMIQALSSHDAGT	CUL7	181	Q14999
RSNTLDIMDGRINHS	FRYL	1956	O94915
DIMDGRINHSSSLAR	FRYL	1961	O94915
RLRQTDMAGSSQNHL	KIF21B	1061	O75037
MSELVHSRLQQGAGA	ZFPM1	546	Q8IX07
VHGRLMDNSTSVREA	NIPBL	1816	Q6KC79
RMDRLAVGFSTHQRS	NRXN2	1161	Q9P2S2
TSLRFRLDAHGQAMV	NOTCH3	1541	Q9UM47
SSNRRMNSLTLNRHT	COG8	136	Q96MW5
ASNTGMHRRQITDLL	LRBA	2576	P50851
NNTRVVGHSIARMLD	LIPG	136	Q9Y5X9
TNLEHTTGQLTTMNR	KNL1	811	Q8NG31
IAHAGQGVSQTLRAM	LHX4	341	Q969G2
SDLHSLVIRGASMVQ	LGR4	296	Q9BXB1
TARMRGHQLLSADVD	NSF	411	P46459
GQVNHALAAAMRTLV	TUBGCP2	286	Q9BSJ2
REMFNSHRLGIENST	FOXC2	451	Q99958
HAEATLGSGNLRMAV	MOB1B	31	Q7L9L4
MVQASGHRRSTRGSK	AQP7	1	O14520
VHMLRDSASDSQRLG	EPHA10	676	Q5JZY3
AQAGAMRRQQHTLRD	HAUS5	131	O94927
DRTLSELMSQTGHLG	LAMA5	2286	O15230
RSVGATNMNEHSSRS	KIF3A	206	Q9Y496
HALLANGSVMSRVGT	EIF2B4	406	Q9UI10
ILNMSSGIVNVSERH	GPR52	11	Q9Y2T5
VVLGQHQSRALAESM	GREB1L	571	Q9C091
NGRDTALMVTRVVNH	PTPRT	231	O14522
LASRGQHSNVDMLVR	PANK4	241	Q9NVE7
EMRSQGATRELLIHQ	OBSCN	4116	Q5VST9
SQHFRLDMGSRVDGS	PCDHAC1	166	Q9H158
REAHAQSIGMNRLTE	MCM3	756	P25205
MDRLAVGFSTHQRSA	NRXN2	116	P58401
RLSQSGHMLLNLSRG	RGPD3	351	A6NKT7
AQHIRSLMEERFGTS	APC2	191	O95996
RISRNAVTSMSIRGH	FAM126A	311	Q9BYI3
NNAMQADDSGHRTRR	IGSF10	2081	Q6WRI0
MGTASRSNIARHLQT	IGSF6	1	O95976
TRLGSTDVAASQHML	HEATR5A	401	Q86XA9
RTMQGARDVAHSIIF	ATG7	271	O95352
STERQMSHDLVAVGR	BCLAF3	431	A2AJT9
RFVQEHSSSQGMRNI	BLM	1086	P54132
LDAGAQHSTMTSTLR	CCDC138	436	Q96M89
GVMQARLQHLSSLES	DOCK11	1361	Q5JSL3
LGLTEQAMGTSRIQH	CPLANE1	2866	Q9H799
HRGALMDSQQASGTI	CHRDL1	231	Q9BU40
TTHTLRMIGENSGLV	EPM2AIP1	246	Q7L775
AAMTHLGIRSSSGLQ	CRTC3	311	Q6UUV7
VMTDRVSLNHRQDGG	CPAMD8	696	Q8IZJ3
LNRISQMHRVSCSGG	COL6A3	1866	P12111
NTNQRSHDSRSMALP	PYHIN1	401	Q6K0P9
TTNVRGETALHMAAR	ANK3	461	Q12955
STSLMQTLGNHSRGE	CEP85L	126	Q5SZL2
LEMAQHSQRSRSVSG	BRSK1	421	Q8TDC3
IARHLAQVGDSMDRS	BID	86	P55957
SGDRMGTLRVHELQS	MAPKBP1	496	O60336
LSSAVSAVIHGRNMG	MBD5	1136	Q9P267
GSHVLVEANLSGRMT	HUS1B	176	Q8NHY5
SAPITSASRMQSNRH	ATAT1	61	Q5SQI0
NAVHGAMRVLTEFTR	IPO9	161	Q96P70
GQTALMLAISHGRQD	KANK3	696	Q6NY19
RRMLATDGAAQQAHT	KANSL2	281	Q9H9L4
SDNSVLHRLISGVMT	SLC44A1	196	Q8WWI5
VNDERLTTIAHNMSG	EMSY	71	Q7Z589
VRQMNGTLRSHSRDI	EMILIN2	741	Q9BXX0
QTEIDMRISGLSHTQ	CCDC168	2461	Q8NDH2
DATQLLSHGQRMLAA	HBM	51	Q6B0K9
RRTVNMLTSFCGALH	GRIA1	91	P42261
VRTASRQTSMHLGSL	GPATCH2	421	Q9NW75
HSASNRRMSGEPIQT	RPRD2	1091	Q5VT52
MLGNRTLSSRHIDVC	SLC12A6	376	Q9UHW9
VSSSLRDGMSHLIQS	SLC12A7	766	Q9Y666
ASTAGVRLMLHEQRS	SCNN1B	311	P51168
QARLHTRGAAEMVLQ	RYR1	3766	P21817
GSLTINVHRGSLAMS	CFAP47	6	Q6ZTR5
NVHRGSLAMSIQRGS	CFAP47	11	Q6ZTR5
TLERSQITRDHMGQL	EIF4G3	1266	O43432
MNTTSHHIGQLRSDL	CDH19	56	Q9H159
MHLDSLSSTRGRGQQ	CFAP74	1381	Q9C0B2
TAMNQRSSRSHALVT	KIFC2	591	Q96AC6
ARMNRVLSFHSVSGI	D2HGDH	151	Q8N465
ILHENNVSRSLGMNA	MED1	241	Q15648
RRMAAGNHSTVTEFI	OR8A1	16	Q8NGG7
MSEHVTRSQSSERGN	PAGE5	21	Q96GU1
MSHFSLRLEGGRQDS	PCGF6	101	Q9BYE7
DRLSQSGHMLLNLSR	RGPD1	341	P0DJD0
RELSGLRTQVHQSMV	MROH5	1156	Q6ZUA9
QRHTQSMSSARERLE	HMG20B	221	Q9P0W2
VRQPSLHMSAAAASR	MTA3	216	Q9BTC8
VVRSGASLLSNMSRH	PKP1	611	Q13835
GSHRISQMITSEGNV	DSCAM	451	O60469
TSSLRISNLSLMHNG	DSCAM	651	O60469
QGNHMTVRTLSTFRN	RBP5	46	P82980
NTIAMHSGVDTSVLR	SESN2	376	P58004
HSAVLGISDLMSQRN	RGMB	106	Q6NW40
RLSQSGHMLLNLSRG	RGPD4	351	Q7Z3J3
LSGLRSNLSMISHGQ	STRADA	211	Q7RTN6
SNLSMISHGQRQRVV	STRADA	216	Q7RTN6
LAMPSDQRGSRQTDH	TEX55	166	Q96M34
HGRRSNLDLMANSVE	PLCD4	96	Q9BRC7
SLGRHTRQMLQNGTS	TAS2R3	206	Q9NYW6
QVAGSMRDRDLLHNS	SYNE3	521	Q6ZMZ3
SGISGLRNHMTSLNL	TAB2	66	Q9NYJ8
RMNGSRTLTHSISDG	TAB2	96	Q9NYJ8
GLRLAQTHRDALTMS	TMEM161A	246	Q9NX61
GISLDLSLNAHRSMQ	SYNJ1	136	O43426
SGTRDSTDMLVHNLV	TOGARAM2	646	Q6ZUX3
LQREVAQRTSEGAMH	NCKAP5	56	O14513
NMGHSNTEIDVTSLR	AHCYL1	396	O43865
DGDHMIIRTLSTFRN	RBP1	46	P09455
GHFRMGTLLSRQSVQ	YARS2	191	Q9Y2Z4
EQLSARGMDASLSHQ	HAUS1	201	Q96CS2
RGMDASLSHQSLVAL	HAUS1	206	Q96CS2
DLSHDQRTLITGMAS	NBEA	2911	Q8NFP9
MLQLAGRGSAVHQLS	EPPK1	3481	P58107
IQSVRRHTNSMLEGT	PTPN14	1096	Q15678
RHAVAVLSITAANMG	SMARCAL1	776	Q9NZC9
FRSMIVHSEGQLRSL	PRSS47P	251	A8MTI9
SAIMGHQERLRDQTR	KIAA1217	106	Q5T5P2
RSIHEGIATAIMNSD	SIAH1	241	Q8IUQ4
TGNRKTSQSGREMAH	SHROOM4	976	Q9ULL8
TTTQVGMHDIVRSFR	SLC3A1	351	Q07837
VLLLQGNMGHARSSN	SIX1	231	Q15475
LSCHGTRMRQIASDS	TANC2	386	Q9HCD6
SLNREMDSLGSNHSI	TAOK3	336	Q9H2K8
MTLASRLSTAANIGH	SLC41A1	151	Q8IVJ1
NGHALDSQRVSMRTG	MYBPH	211	Q13203
AIVSMVNNSTTHRGG	SLC17A7	86	Q9P2U7
RHGERRNSNVSQASM	SCN3A	616	Q9NY46
EALNAMTSNGSHRLI	STIM1	546	Q13586
AMTHLSGHSRLQARN	MLXIPL	346	Q9NP71
QGAITERLRSFSMHD	REEP3	141	Q6NUK4
HALEQGGLRAATMSA	PYCR3	246	Q53H96
TLDGLTGVSQDHMRA	SLC35B1	181	P78383
TIHGNTEELRQMAAS	SGCA	336	Q16586
MVRLGARSDSAHQID	SERPINB12	41	Q96P63
DMGHSAEATQALLRR	SPTBN5	3026	Q9NRC6
LMNGLSSLRGHRRAS	ARHGAP22	461	Q7Z5H3
SNLTEIHDQISGMAR	SEMA5A	146	Q13591
MGNTSSERAALERHG	PRKAB1	1	Q9Y478
LAVASRSNHSLVVGM	ANKDD1B	371	A6NHY2
VNVRSRNMGGTHRQT	CILP	966	O75339
TLSQGSAATLHMAVR	CHST5	101	Q9GZS9
SQGSAATLHMAVRDL	CHST6	81	Q9GZX3
LGRHTRQMRNTVAGS	TAS2R1	201	Q9NYW7
MSGQSLTDRITAAQH	PICALM	1	Q13492
HNRVRQILMASGSTT	PRPF8	1241	Q6P2Q9
GESFNQRTTLILHMR	ZNF667	206	Q5HYK9
HMQGSGSLAQAVIRE	RNF213	3901	Q63HN8
VRASAQRMGDTHTGL	VWA1	101	Q6PCB0
LVSGLMRTSVGHQDA	PLK3	371	Q9H4B4
SSRRVAVLFNDGTHM	PLK3	481	Q9H4B4
SSLMLSQGQHLDVSR	TULP4	1151	Q9NRJ4
RNGLAQRMSHGNKSS	STK35	271	Q8TDR2
LISFQTHIRMNSGER	ZNF700	346	Q9H0M5
VSIVMRSAGHSQISR	VPS13A	2686	Q96RL7
SNASSGLTAQARIIM	VNN1	486	O95497
QTVSLSHLSQGEVRM	SPEN	3086	Q96T58
RSGQIEGVRQMHSNA	PHIP	691	Q8WWQ0
GILSQMGRHSQSRSH	SRRM5	321	B3KS81
MVSNGSTLLNHTSDR	SLC26A2	196	P50443
MRSDEVNLVATGHQS	SAGE1	31	Q9NXZ1
RSVGATNMNEHSSRS	KIF3B	201	O15066
IENGVSMHRFLTISR	TRPM3	531	Q9HCF6
VDGEISASHVSRMLN	ROPN1	171	Q9HAT0
LTQDGSRAQQMALHT	SPATA20	286	Q8TB22
GHRRTMSQDLRQLSD	ARHGAP25	481	P42331
LMAITRHGVNRQDTG	POLR2A	1411	P24928
QEQVRATSQGGHLMS	WASH2P	396	Q6VEQ5
QVRATSQGGHLMSDL	WASH4P	411	A8MWX3
QSSTGFMEGLSRHLI	TMEM131	911	Q92545
QEGHFRSNTQLGRMI	TRIM75	61	A6NK02
HQESMNTGTLASLRG	USP17L18	496	D6R9N7
QEQVRATSQGGHLMS	WASHC1	396	A8K0Z3
NHMRGRSITNDSAVL	HGS	426	O14964
MAVNQSHTENRRGAL	WBP2NL	1	Q6ICG8
HQESMNTGTLASLRG	USP17L5	496	A8MUK1
HQESMNTGTLASLRG	USP17L21	496	D6R901
HQESMNTGTLASLRG	USP17L13	496	C9JLJ4
QVRATSQGGHLMSDL	WASH3P	396	C4AMC7
DTILNSNHIGRMAVA	MRPL2	161	Q5T653
HQESMNTGTLASLRG	USP17L19	496	D6RCP7
SSLHMNRVIAGVTES	PPP1R3F	651	Q6ZSY5
LHNGINRDSSMTAIT	RALGAPB	461	Q86X10
MEGQRQESHATLTLA	TTC32	1	Q5I0X7
HQESMNTGTLASLRG	USP17L12	496	C9JPN9
HQESMNTGTLASLRG	USP17L24	496	Q0WX57
VRMIRSGGLHCSSNA	WASHC4	926	Q2M389
SSRALMNLHNNEAGR	WNT4	181	P56705
LHLLQSTRVGMSVNA	TCEA2	41	Q15560
EAIREHQMARTGGTQ	TCEA2	241	Q15560
QEEMHSSLRSLRNSA	TOGARAM1	966	Q9Y4F4
HQESMNTGTLASLRG	USP17L22	496	D6RA61
TSGHSVAGVLDQSRM	ZNF711	271	Q9Y462
TFATRTGSRQGIEMH	SNTB2	401	Q13425
NHQSREVEMSTRGRF	SIGLEC10	76	Q96LC7
TMVTGNATRDLTLHQ	SLC18A2	86	Q05940
HQESMNTGTLASLRG	USP17L15	496	C9J2P7
HQESMNTGTLASLRG	USP17L17	496	D6RBQ6
ADSLRVLSGHLMQTR	ZC3H14	491	Q6PJT7
EGSLSAMSGRNELHS	ZFYVE26	801	Q68DK2
SLIQATHVAMRGNSD	TCTN2	511	Q96GX1
MRDFTNVQNVGRHLT	ZNF781	141	Q8N8C0
RNHMSVSNVGRLSLV	ZNF781	226	Q8N8C0
HQESMNTGTLASLRG	USP17L20	496	D6RJB6
GTHTSLMQRLRNRGE	UBR5	2321	O95071
TSGHLSQQDLESQMR	ULK4	396	Q96C45
MQHLDRQAAALTRNG	CX3CL1	86	P78423
HQESMNTGTLASLRG	USP17L11	496	C9JVI0
LHMLSSVDLNGQDRR	VLDLR	621	P98155
NHRTNRLAMGVAASL	GARIN5B	61	Q8N5Q1
VSMRLHRGAPANVSS	CSNK1E	376	P49674
TTDSAHGLQMLRTIG	KLHL29	286	Q96CT2
HELGPNRRSSQSEDM	KLHL42	401	Q9P2K6
RMSGELQSHVSISVQ	KRT77	476	Q7Z794
LAERSNHEGSSQRMP	MZT2A	121	Q6P582
ARSSQQGSSVMRQIH	MYO7B	1031	Q6PIF6
QGSSVMRQIHDTLGR	MYO7B	1036	Q6PIF6
REAQGGQRLLLSTMH	MYO7B	1461	Q6PIF6
VGRLHFSETTANNMR	MYRF	476	Q9Y2G1
RQGGRTALHLATEME	NFKB2	631	Q00653