Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	TRPV1 RYR2 RYR3	5.95e-06	18	40	3	GO:0015278
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR2 RYR3	2.34e-05	4	40	2	GO:0005219
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	TRPV1 RYR2 RYR3	3.22e-05	31	40	3	GO:0099604
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	TRPV1 RYR2 RYR3	3.90e-05	33	40	3	GO:0005217
GeneOntologyMolecularFunction	sodium:bicarbonate symporter activity	SLC4A4 SLC4A9	5.84e-05	6	40	2	GO:0008510
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR2 RYR3	5.84e-05	6	40	2	GO:0048763
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	TRPV1 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	2.20e-04	627	40	7	GO:0022890
GeneOntologyMolecularFunction	dystroglycan binding	CLASP2 CLASP1	2.55e-04	12	40	2	GO:0002162
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC4A4 SLC4A9	3.01e-04	13	40	2	GO:0140410
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	TRPV1 SLC4A4 SLC4A9 RYR2 RYR3 SCN4A	3.03e-04	465	40	6	GO:0046873
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	TRPV1 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	3.12e-04	664	40	7	GO:0008324
GeneOntologyMolecularFunction	monoatomic cation channel activity	TRPV1 NOX5 RYR2 RYR3 SCN4A	5.83e-04	343	40	5	GO:0005261
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	TRPV1 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	6.90e-04	758	40	7	GO:0015318
GeneOntologyMolecularFunction	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	TXNRD1 NOX5	7.27e-04	20	40	2	GO:0050664
GeneOntologyMolecularFunction	microtubule plus-end binding	CLASP2 CLASP1	8.81e-04	22	40	2	GO:0051010
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	TRPV1 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	9.00e-04	793	40	7	GO:0015075
GeneOntologyMolecularFunction	calmodulin binding	TRPV1 CAMKV RYR2 RYR3	1.13e-03	230	40	4	GO:0005516
GeneOntologyMolecularFunction	dynein light intermediate chain binding	CCDC88A DNAH1	1.43e-03	28	40	2	GO:0051959
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	EXO1 MSH5 ARID1A CHD5	1.83e-03	262	40	4	GO:0140097
GeneOntologyMolecularFunction	bicarbonate transmembrane transporter activity	SLC4A4 SLC4A9	1.87e-03	32	40	2	GO:0015106
GeneOntologyMolecularFunction	solute:inorganic anion antiporter activity	SLC4A4 SLC4A9	1.87e-03	32	40	2	GO:0005452
GeneOntologyMolecularFunction	transmembrane transporter activity	TRPV1 ABCA2 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	2.05e-03	1180	40	8	GO:0022857
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	MSH5 ARID1A CHD5	2.09e-03	127	40	3	GO:0008094
GeneOntologyMolecularFunction	monoatomic ion channel activity	TRPV1 NOX5 RYR2 RYR3 SCN4A	2.13e-03	459	40	5	GO:0005216
GeneOntologyMolecularFunction	calcium channel activity	TRPV1 RYR2 RYR3	2.19e-03	129	40	3	GO:0005262
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	ARID1A CHD5	2.49e-03	37	40	2	GO:0140658
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	TRPV1 RYR2 RYR3	2.76e-03	140	40	3	GO:0099094
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	TRPV1 RYR2 RYR3	3.41e-03	151	40	3	GO:0015085
GeneOntologyMolecularFunction	transporter activity	TRPV1 ABCA2 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	3.55e-03	1289	40	8	GO:0005215
GeneOntologyMolecularFunction	channel activity	TRPV1 NOX5 RYR2 RYR3 SCN4A	3.80e-03	525	40	5	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TRPV1 NOX5 RYR2 RYR3 SCN4A	3.83e-03	526	40	5	GO:0022803
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC4A4 SLC4A9 SCN4A	4.83e-03	171	40	3	GO:0015081
GeneOntologyMolecularFunction	transcription corepressor binding	PER1 PER2	6.23e-03	59	40	2	GO:0001222
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	TRPV1 RYR2 RYR3	6.75e-03	193	40	3	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	TRPV1 RYR2 RYR3	7.15e-03	197	40	3	GO:0022834
GeneOntologyMolecularFunction	ATP-dependent activity	ABCA2 MSH5 ARID1A CHD5 DNAH1	7.31e-03	614	40	5	GO:0140657
GeneOntologyMolecularFunction	endopeptidase regulator activity	A2M ABCA2 PSMD14	7.55e-03	201	40	3	GO:0061135
GeneOntologyBiologicalProcess	positive regulation of extracellular matrix disassembly	TGFB2 CLASP2 CLASP1	8.03e-07	10	40	3	GO:0090091
GeneOntologyBiologicalProcess	regulation of extracellular matrix disassembly	TGFB2 CLASP2 CLASP1	1.51e-05	25	40	3	GO:0010715
GeneOntologyBiologicalProcess	circadian regulation of translation	PER1 PER2	2.19e-05	4	40	2	GO:0097167
GeneOntologyBiologicalProcess	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	CLASP2 CLASP1	3.65e-05	5	40	2	GO:1904261
GeneOntologyBiologicalProcess	regulation of basement membrane assembly involved in embryonic body morphogenesis	CLASP2 CLASP1	3.65e-05	5	40	2	GO:1904259
GeneOntologyBiologicalProcess	negative regulation of wound healing, spreading of epidermal cells	CLASP2 CLASP1	3.65e-05	5	40	2	GO:1903690
GeneOntologyBiologicalProcess	basement membrane assembly involved in embryonic body morphogenesis	CLASP2 CLASP1	3.65e-05	5	40	2	GO:2001197
GeneOntologyBiologicalProcess	positive regulation of extracellular matrix organization	TGFB2 CLASP2 CLASP1	3.88e-05	34	40	3	GO:1903055
GeneOntologyBiologicalProcess	chromosome organization	ASCC1 EXO1 KNTC1 CLASP2 MSH5 ARID1A CLASP1 NCAPH	4.31e-05	686	40	8	GO:0051276
GeneOntologyBiologicalProcess	exit from mitosis	KNTC1 CLASP2 CLASP1	5.02e-05	37	40	3	GO:0010458
GeneOntologyBiologicalProcess	monoatomic cation transport	TGFB2 PER1 GRAMD2A TRPV1 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	5.36e-05	1157	40	10	GO:0006812
GeneOntologyBiologicalProcess	nuclear chromosome segregation	KNTC1 CLASP2 MSH5 ARID1A CLASP1 NCAPH	5.93e-05	356	40	6	GO:0098813
GeneOntologyBiologicalProcess	cellular response to alkaloid	TRPV1 RYR2 RYR3	6.35e-05	40	40	3	GO:0071312
GeneOntologyBiologicalProcess	circulatory system process	TGFB2 TRPV1 ABCA2 SLC4A4 PER2 BCR RYR2 SCN4A	6.87e-05	733	40	8	GO:0003013
GeneOntologyBiologicalProcess	negative regulation of toll-like receptor 2 signaling pathway	TLR6 MFHAS1	7.65e-05	7	40	2	GO:0034136
GeneOntologyBiologicalProcess	metal ion transport	TGFB2 PER1 GRAMD2A TRPV1 SLC4A4 SLC4A9 RYR2 RYR3 SCN4A	1.00e-04	1000	40	9	GO:0030001
GeneOntologyBiologicalProcess	sister chromatid segregation	KNTC1 CLASP2 ARID1A CLASP1 NCAPH	1.26e-04	254	40	5	GO:0000819
GeneOntologyBiologicalProcess	catagen	TGFB2 TRPV1	1.31e-04	9	40	2	GO:0042637
GeneOntologyBiologicalProcess	regulation of actin filament-based process	TGFB2 CLASP2 CCDC88A CCL27 CLASP1 RYR2	1.84e-04	438	40	6	GO:0032970
GeneOntologyBiologicalProcess	regulation of basement membrane organization	CLASP2 CLASP1	1.99e-04	11	40	2	GO:0110011
GeneOntologyBiologicalProcess	cellular response to caffeine	RYR2 RYR3	1.99e-04	11	40	2	GO:0071313
GeneOntologyBiologicalProcess	regulation of wound healing, spreading of epidermal cells	CLASP2 CLASP1	1.99e-04	11	40	2	GO:1903689
GeneOntologyBiologicalProcess	monoatomic ion transport	TGFB2 PER1 GRAMD2A TRPV1 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	2.23e-04	1374	40	10	GO:0006811
GeneOntologyBiologicalProcess	basement membrane assembly	CLASP2 CLASP1	2.39e-04	12	40	2	GO:0070831
GeneOntologyBiologicalProcess	chromosome segregation	KNTC1 CLASP2 MSH5 ARID1A CLASP1 NCAPH	2.55e-04	465	40	6	GO:0007059
GeneOntologyBiologicalProcess	regulation of toll-like receptor 2 signaling pathway	TLR6 MFHAS1	2.82e-04	13	40	2	GO:0034135
GeneOntologyBiologicalProcess	response to purine-containing compound	PER1 TRPV1 RYR2 RYR3	2.95e-04	166	40	4	GO:0014074
GeneOntologyBiologicalProcess	actin filament-based process	TGFB2 CLASP2 CCDC88A CCL27 CLASP1 BCR RYR2 SCN4A	3.09e-04	912	40	8	GO:0030029
GeneOntologyBiologicalProcess	cellular response to purine-containing compound	RYR2 RYR3	3.29e-04	14	40	2	GO:0071415
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	TGFB2 TRPV1 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	3.32e-04	922	40	8	GO:0098662
GeneOntologyBiologicalProcess	positive regulation of extracellular matrix assembly	CLASP2 CLASP1	3.79e-04	15	40	2	GO:1901203
GeneOntologyBiologicalProcess	embryonic body morphogenesis	CLASP2 CLASP1	3.79e-04	15	40	2	GO:0010172
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	TGFB2 TRPV1 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	3.84e-04	942	40	8	GO:0098655
GeneOntologyBiologicalProcess	embryonic morphogenesis	TXNRD1 TGFB2 CLASP2 ARID1A CLASP1 BCR RYR2	3.95e-04	713	40	7	GO:0048598
GeneOntologyBiologicalProcess	extracellular matrix disassembly	TGFB2 CLASP2 CLASP1	4.14e-04	75	40	3	GO:0022617
GeneOntologyBiologicalProcess	nuclear receptor-mediated glucocorticoid signaling pathway	PER1 ARID1A	4.90e-04	17	40	2	GO:0042921
GeneOntologyBiologicalProcess	nuclear receptor-mediated corticosteroid signaling pathway	PER1 ARID1A	5.50e-04	18	40	2	GO:0031958
GeneOntologyBiologicalProcess	regulation of extracellular matrix organization	TGFB2 CLASP2 CLASP1	5.77e-04	84	40	3	GO:1903053
GeneOntologyBiologicalProcess	positive regulation of sequestering of calcium ion	TGFB2 RYR2	6.14e-04	19	40	2	GO:0051284
GeneOntologyBiologicalProcess	toll-like receptor 2 signaling pathway	TLR6 MFHAS1	6.14e-04	19	40	2	GO:0034134
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	TGFB2 TRPV1 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	6.39e-04	1017	40	8	GO:0098660
GeneOntologyBiologicalProcess	regulation of gastrulation	CLASP2 CLASP1	6.82e-04	20	40	2	GO:0010470
GeneOntologyBiologicalProcess	mitotic sister chromatid segregation	KNTC1 CLASP2 CLASP1 NCAPH	7.42e-04	212	40	4	GO:0000070
GeneOntologyBiologicalProcess	gastrulation	TXNRD1 CLASP2 ARID1A CLASP1	7.42e-04	212	40	4	GO:0007369
GeneOntologyBiologicalProcess	cellular response to ATP	TRPV1 RYR3	7.52e-04	21	40	2	GO:0071318
GeneOntologyBiologicalProcess	response to caffeine	RYR2 RYR3	7.52e-04	21	40	2	GO:0031000
GeneOntologyBiologicalProcess	calcium ion transmembrane import into cytosol	TGFB2 TRPV1 RYR2 RYR3	8.09e-04	217	40	4	GO:0097553
GeneOntologyBiologicalProcess	regulation of actin cytoskeleton organization	TGFB2 CLASP2 CCDC88A CCL27 CLASP1	8.39e-04	384	40	5	GO:0032956
GeneOntologyBiologicalProcess	focal adhesion assembly	CLASP2 CLASP1 BCR	8.78e-04	97	40	3	GO:0048041
GeneOntologyBiologicalProcess	activation of protein kinase activity	TGFB2 CCDC88A TLR6	8.78e-04	97	40	3	GO:0032147
GeneOntologyBiologicalProcess	hair cycle phase	TGFB2 TRPV1	9.04e-04	23	40	2	GO:0044851
GeneOntologyBiologicalProcess	negative regulation of protein-containing complex disassembly	CLASP2 PER2 CLASP1	9.59e-04	100	40	3	GO:0043242
GeneOntologyBiologicalProcess	response to magnesium ion	RYR2 RYR3	1.07e-03	25	40	2	GO:0032026
GeneOntologyBiologicalProcess	entrainment of circadian clock by photoperiod	PER1 PER2	1.07e-03	25	40	2	GO:0043153
GeneOntologyBiologicalProcess	cardiac left ventricle morphogenesis	TGFB2 RYR2	1.07e-03	25	40	2	GO:0003214
GeneOntologyBiologicalProcess	negative regulation of cytosolic calcium ion concentration	RYR2 RYR3	1.07e-03	25	40	2	GO:0051481
GeneOntologyBiologicalProcess	microtubule anchoring	CLASP2 CLASP1	1.07e-03	25	40	2	GO:0034453
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	TGFB2 TRPV1 SLC4A4 NOX5 SLC4A9 RYR2 RYR3 SCN4A	1.16e-03	1115	40	8	GO:0034220
GeneOntologyBiologicalProcess	regulation of stress fiber assembly	CLASP2 CCDC88A CLASP1	1.17e-03	107	40	3	GO:0051492
GeneOntologyBiologicalProcess	cell-substrate junction assembly	CLASP2 CLASP1 BCR	1.20e-03	108	40	3	GO:0007044
GeneOntologyBiologicalProcess	wound healing, spreading of epidermal cells	CLASP2 CLASP1	1.34e-03	28	40	2	GO:0035313
GeneOntologyBiologicalProcess	photoperiodism	PER1 PER2	1.34e-03	28	40	2	GO:0009648
GeneOntologyBiologicalProcess	cell-substrate junction organization	CLASP2 CLASP1 BCR	1.44e-03	115	40	3	GO:0150115
GeneOntologyBiologicalProcess	regulation of extracellular matrix assembly	CLASP2 CLASP1	1.44e-03	29	40	2	GO:1901201
GeneOntologyBiologicalProcess	hair follicle maturation	TGFB2 TRPV1	1.44e-03	29	40	2	GO:0048820
GeneOntologyBiologicalProcess	DNA repair	ASCC1 EXO1 MSH5 AUNIP ARID1A PSMD14	1.45e-03	648	40	6	GO:0006281
GeneOntologyBiologicalProcess	blood circulation	TGFB2 TRPV1 PER2 BCR RYR2 SCN4A	1.45e-03	648	40	6	GO:0008015
GeneOntologyBiologicalProcess	entrainment of circadian clock	PER1 PER2	1.54e-03	30	40	2	GO:0009649
GeneOntologyBiologicalProcess	maintenance of location in cell	TGFB2 CCDC88A RYR2 RYR3	1.56e-03	259	40	4	GO:0051651
GeneOntologyBiologicalProcess	regulation of actomyosin structure organization	CLASP2 CCDC88A CLASP1	1.70e-03	122	40	3	GO:0110020
GeneOntologyBiologicalProcess	regulation of actin filament bundle assembly	CLASP2 CCDC88A CLASP1	1.74e-03	123	40	3	GO:0032231
GeneOntologyBiologicalProcess	regulation of hair cycle	TGFB2 PER1	1.75e-03	32	40	2	GO:0042634
GeneOntologyBiologicalProcess	response to alkaloid	TRPV1 RYR2 RYR3	1.82e-03	125	40	3	GO:0043279
GeneOntologyBiologicalProcess	stress fiber assembly	CLASP2 CCDC88A CLASP1	1.91e-03	127	40	3	GO:0043149
GeneOntologyBiologicalProcess	contractile actin filament bundle assembly	CLASP2 CCDC88A CLASP1	1.91e-03	127	40	3	GO:0030038
GeneOntologyBiologicalProcess	sodium ion transport	PER1 SLC4A4 SLC4A9 SCN4A	1.94e-03	275	40	4	GO:0006814
GeneOntologyBiologicalProcess	regulation of epithelial to mesenchymal transition	TGFB2 CLASP2 CLASP1	2.04e-03	130	40	3	GO:0010717
GeneOntologyBiologicalProcess	mismatch repair	EXO1 MSH5	2.10e-03	35	40	2	GO:0006298
GeneOntologyBiologicalProcess	cell division	TGFB2 KNTC1 CLASP2 CLASP1 NCAPH NOX5	2.10e-03	697	40	6	GO:0051301
GeneOntologyCellularComponent	kinetochore microtubule	KNTC1 CLASP2 CLASP1	9.75e-06	22	40	3	GO:0005828
GeneOntologyCellularComponent	cortical microtubule cytoskeleton	CLASP2 CLASP1	3.56e-05	5	40	2	GO:0030981
GeneOntologyCellularComponent	basal cortex	CLASP2 CLASP1	7.45e-05	7	40	2	GO:0045180
GeneOntologyCellularComponent	NSL complex	PHF20 PHF20L1	1.94e-04	11	40	2	GO:0044545
GeneOntologyCellularComponent	condensed chromosome	KNTC1 CLASP2 MSH5 CLASP1 NCAPH	2.86e-04	307	40	5	GO:0000793
GeneOntologyCellularComponent	spindle microtubule	KNTC1 CLASP2 CLASP1	5.95e-04	86	40	3	GO:0005876
GeneOntologyCellularComponent	basal part of cell	CLASP2 SLC4A4 CLASP1 PROM2 SLC4A9	7.36e-04	378	40	5	GO:0045178
GeneOntologyCellularComponent	axonemal dynein complex	DNAI1 DNAH1	1.04e-03	25	40	2	GO:0005858
GeneOntologyCellularComponent	microtubule plus-end	CLASP2 CLASP1	1.31e-03	28	40	2	GO:0035371
GeneOntologyCellularComponent	microtubule end	CLASP2 CLASP1	2.40e-03	38	40	2	GO:1990752
GeneOntologyCellularComponent	microtubule	KNTC1 DNAI1 CLASP2 CLASP1 DNAH1	3.33e-03	533	40	5	GO:0005874
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	PHF20 PHF20L1	3.36e-03	45	40	2	GO:1902562
GeneOntologyCellularComponent	sarcoplasmic reticulum membrane	RYR2 RYR3	3.36e-03	45	40	2	GO:0033017
GeneOntologyCellularComponent	cell cortex region	CLASP2 CLASP1	3.36e-03	45	40	2	GO:0099738
GeneOntologyCellularComponent	smooth endoplasmic reticulum	RYR2 RYR3	3.50e-03	46	40	2	GO:0005790
GeneOntologyCellularComponent	dynein complex	DNAI1 DNAH1	4.80e-03	54	40	2	GO:0030286
GeneOntologyCellularComponent	cytoplasmic region	DNAI1 CLASP2 CLASP1 DNAH1	4.85e-03	360	40	4	GO:0099568
GeneOntologyCellularComponent	kinetochore	KNTC1 CLASP2 CLASP1	4.99e-03	181	40	3	GO:0000776
GeneOntologyCellularComponent	condensed chromosome, centromeric region	KNTC1 CLASP2 CLASP1	5.96e-03	193	40	3	GO:0000779
Domain	DUF3776	PHF20 PHF20L1	4.25e-06	2	39	2	PF12618
Domain	DUF3776	PHF20 PHF20L1	4.25e-06	2	39	2	IPR022255
Domain	Ryanrecept_TM4-6	RYR2 RYR3	1.27e-05	3	39	2	IPR009460
Domain	Period_circadian-like_C	PER1 PER2	1.27e-05	3	39	2	IPR022728
Domain	RyR	RYR2 RYR3	1.27e-05	3	39	2	PF02026
Domain	Ryanodine_rcpt	RYR2 RYR3	1.27e-05	3	39	2	IPR003032
Domain	Period_C	PER1 PER2	1.27e-05	3	39	2	PF12114
Domain	RR_TM4-6	RYR2 RYR3	1.27e-05	3	39	2	PF06459
Domain	Ryan_recept	RYR2 RYR3	1.27e-05	3	39	2	IPR013333
Domain	CLASP_N	CLASP2 CLASP1	2.54e-05	4	39	2	PF12348
Domain	CLASP_N_dom	CLASP2 CLASP1	2.54e-05	4	39	2	IPR024395
Domain	Na/HCO3_transpt	SLC4A4 SLC4A9	4.23e-05	5	39	2	IPR003024
Domain	RIH_assoc	RYR2 RYR3	6.34e-05	6	39	2	PF08454
Domain	RIH_assoc-dom	RYR2 RYR3	6.34e-05	6	39	2	IPR013662
Domain	RIH_dom	RYR2 RYR3	6.34e-05	6	39	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 RYR3	6.34e-05	6	39	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 RYR3	6.34e-05	6	39	2	IPR015925
Domain	-	RYR2 RYR3	6.34e-05	6	39	2	1.25.10.30
Domain	RYDR_ITPR	RYR2 RYR3	6.34e-05	6	39	2	PF01365
Domain	Ins145_P3_rec	RYR2 RYR3	6.34e-05	6	39	2	PF08709
Domain	Ion_trans_dom	TRPV1 RYR2 RYR3 SCN4A	9.18e-05	114	39	4	IPR005821
Domain	Ion_trans	TRPV1 RYR2 RYR3 SCN4A	9.18e-05	114	39	4	PF00520
Domain	Band3_cytoplasmic_dom	SLC4A4 SLC4A9	1.52e-04	9	39	2	IPR013769
Domain	Band_3_cyto	SLC4A4 SLC4A9	1.52e-04	9	39	2	PF07565
Domain	-	SLC4A4 SLC4A9	1.52e-04	9	39	2	3.40.1100.10
Domain	MIR	RYR2 RYR3	1.89e-04	10	39	2	PS50919
Domain	MIR	RYR2 RYR3	1.89e-04	10	39	2	PF02815
Domain	MIR	RYR2 RYR3	1.89e-04	10	39	2	SM00472
Domain	HCO3_cotransp	SLC4A4 SLC4A9	1.89e-04	10	39	2	PF00955
Domain	HCO3_transpt_C	SLC4A4 SLC4A9	1.89e-04	10	39	2	IPR011531
Domain	MIR_motif	RYR2 RYR3	1.89e-04	10	39	2	IPR016093
Domain	PTrfase/Anion_transptr	SLC4A4 SLC4A9	1.89e-04	10	39	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A4 SLC4A9	1.89e-04	10	39	2	IPR003020
Domain	Zinc_finger_PHD-type_CS	PHF20 PHF20L1 CHD5	3.36e-04	65	39	3	IPR019786
Domain	PAS_fold_3	PER1 PER2	1.05e-03	23	39	2	IPR013655
Domain	PAS_3	PER1 PER2	1.05e-03	23	39	2	PF08447
Domain	ZF_PHD_1	PHF20 PHF20L1 CHD5	1.05e-03	96	39	3	PS01359
Domain	PAS-assoc_C	PER1 PER2	1.14e-03	24	39	2	IPR000700
Domain	PAC	PER1 PER2	1.34e-03	26	39	2	IPR001610
Domain	PAC	PER1 PER2	1.34e-03	26	39	2	SM00086
Domain	PAC	PER1 PER2	1.34e-03	26	39	2	PS50113
Domain	TUDOR	PHF20 PHF20L1	1.44e-03	27	39	2	SM00333
Domain	Tudor	PHF20 PHF20L1	1.78e-03	30	39	2	IPR002999
Domain	PAS	PER1 PER2	2.03e-03	32	39	2	SM00091
Domain	PAS	PER1 PER2	2.29e-03	34	39	2	IPR000014
Domain	PAS	PER1 PER2	2.29e-03	34	39	2	PS50112
Domain	Znf_FYVE_PHD	PHF20 PHF20L1 CHD5	3.55e-03	147	39	3	IPR011011
Domain	EF-hand_1	NOX5 RYR2 RYR3	3.90e-03	152	39	3	PF00036
Domain	-	MTG1 ABCA2 MSH5 MFHAS1 CHD5 DNAH1	4.21e-03	746	39	6	3.40.50.300
Domain	HEAT	CLASP2 CLASP1	4.51e-03	48	39	2	PF02985
Domain	ARM-type_fold	CLASP2 ARID1A CLASP1 RYR3	5.32e-03	339	39	4	IPR016024
Pathway	REACTOME_CELL_CYCLE_CHECKPOINTS	EXO1 KNTC1 CLASP2 PHF20 CLASP1 PSMD14	3.42e-05	271	33	6	MM15388
Pathway	REACTOME_CELL_CYCLE_CHECKPOINTS	EXO1 KNTC1 CLASP2 PHF20 CLASP1 PSMD14	5.09e-05	291	33	6	M16647
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	A2M TRPV1 ABCA2 SLC4A4 PSMD14 SLC4A9 RYR2 RYR3	1.35e-04	681	33	8	MM14985
Pathway	REACTOME_ROLE_OF_ABL_IN_ROBO_SLIT_SIGNALING	CLASP2 CLASP1	1.47e-04	8	33	2	M27351
Pathway	REACTOME_CELL_CYCLE	EXO1 KNTC1 CLASP2 MSH5 PHF20 CLASP1 PSMD14 NCAPH	1.54e-04	694	33	8	M543
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	A2M TRPV1 ABCA2 SLC4A4 PSMD14 SLC4A9 RYR2 RYR3	2.30e-04	736	33	8	M27287
Pathway	REACTOME_BICARBONATE_TRANSPORTERS	SLC4A4 SLC4A9	2.36e-04	10	33	2	M27335
Pathway	REACTOME_BICARBONATE_TRANSPORTERS	SLC4A4 SLC4A9	2.36e-04	10	33	2	MM15073
Pathway	KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY	RYR2 RYR3	2.88e-04	11	33	2	M47958
Pathway	WP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING	RYR2 RYR3	4.08e-04	13	33	2	M39589
Pathway	KEGG_CIRCADIAN_RHYTHM_MAMMAL	PER1 PER2	4.08e-04	13	33	2	M18009
Pathway	REACTOME_CELL_CYCLE	EXO1 KNTC1 CLASP2 PHF20 CLASP1 PSMD14 NCAPH	4.09e-04	603	33	7	MM14635
Pathway	PID_CIRCADIAN_PATHWAY	PER1 PER2	6.25e-04	16	33	2	M95
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	RYR2 RYR3	8.86e-04	19	33	2	M47760
Pathway	REACTOME_SEPARATION_OF_SISTER_CHROMATIDS	KNTC1 CLASP2 CLASP1 PSMD14	9.83e-04	191	33	4	M29614
Pathway	REACTOME_SEPARATION_OF_SISTER_CHROMATIDS	KNTC1 CLASP2 CLASP1 PSMD14	1.02e-03	193	33	4	MM14890
Pathway	KEGG_MEDICUS_REFERENCE_PROMOTION_OF_MICROTUBULE_GROWTH	CLASP2 CLASP1	1.19e-03	22	33	2	M47903
Pathway	REACTOME_MITOTIC_PROMETAPHASE	KNTC1 CLASP2 CLASP1 NCAPH	1.21e-03	202	33	4	MM15362
Pathway	REACTOME_MITOTIC_PROMETAPHASE	KNTC1 CLASP2 CLASP1 NCAPH	1.25e-03	204	33	4	M4217
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPV1 RYR2 RYR3	1.57e-03	99	33	3	MM14910
Pathway	REACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES	KNTC1 CLASP2 CLASP1	1.62e-03	100	33	3	MM14561
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PER1 GRAMD2A CLASP2 ABCA2 PER2 ARID1A BCR PROM2 MFHAS1 CHD5	3.58e-07	1105	40	10	35748872
Pubmed	TGF-β signaling directly regulates transcription and functional expression of the electrogenic sodium bicarbonate cotransporter 1, NBCe1 (SLC4A4), via Smad4 in mouse astrocytes.	TGFB2 SLC4A4	1.29e-06	2	40	2	28568893
Pubmed	Circadian rhythm disruption impairs tissue homeostasis and exacerbates chronic inflammation in the intestine.	PER1 PER2	1.29e-06	2	40	2	28710114
Pubmed	Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.	CLASP2 CLASP1	1.29e-06	2	40	2	16914514
Pubmed	Cardiac Per2 functions as novel link between fatty acid metabolism and myocardial inflammation during ischemia and reperfusion injury of the heart.	PER1 PER2	1.29e-06	2	40	2	23977055
Pubmed	De novo synthesis of PERIOD initiates circadian oscillation in cultured mouse suprachiasmatic nucleus after prolonged inhibition of protein synthesis by cycloheximide.	PER1 PER2	1.29e-06	2	40	2	22236088
Pubmed	Expression of circadian Per1 and Per2 genes in the liver and breast tumor tissues of HER2/neu transgenic mice of different age.	PER1 PER2	1.29e-06	2	40	2	22238756
Pubmed	Masking responses to light in period mutant mice.	PER1 PER2	1.29e-06	2	40	2	21793695
Pubmed	Alterations in the expression of Per1 and Per2 induced by Aβ31-35 in the suprachiasmatic nucleus, hippocampus, and heart of C57BL/6 mouse.	PER1 PER2	1.29e-06	2	40	2	27021954
Pubmed	Prognostic relevance of Period1 (Per1) and Period2 (Per2) expression in human gastric cancer.	PER1 PER2	1.29e-06	2	40	2	24551282
Pubmed	Constant darkness is a circadian metabolic signal in mammals.	PER1 PER2	1.29e-06	2	40	2	16421573
Pubmed	Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock.	PER1 PER2	1.29e-06	2	40	2	11389837
Pubmed	Circadian regulation of central ethanol sensitivity by the mPer2 gene.	PER1 PER2	1.29e-06	2	40	2	19523042
Pubmed	Cocaine sensitization and reward are under the influence of circadian genes and rhythm.	PER1 PER2	1.29e-06	2	40	2	12084940
Pubmed	Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics.	CLASP2 CLASP1	1.29e-06	2	40	2	12837247
Pubmed	Differential daily expression of Per1 and Per2 mRNA in the suprachiasmatic nucleus of fetal and early postnatal mice.	PER1 PER2	1.29e-06	2	40	2	11207804
Pubmed	Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.	RYR2 RYR3	1.29e-06	2	40	2	21531043
Pubmed	Resetting the brain clock: time course and localization of mPER1 and mPER2 protein expression in suprachiasmatic nuclei during phase shifts.	PER1 PER2	1.29e-06	2	40	2	15009158
Pubmed	Insights into structure and activity relationship of clinically mutated PER1 and PER2 class A β-lactamase enzymes.	PER1 PER2	1.29e-06	2	40	2	35475497
Pubmed	Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.	RYR2 RYR3	1.29e-06	2	40	2	16678258
Pubmed	Time-dependent inhibitory effect of lipopolysaccharide injection on Per1 and Per2 gene expression in the mouse heart and liver.	PER1 PER2	1.29e-06	2	40	2	20370466
Pubmed	cAMP-dependent signaling as a core component of the mammalian circadian pacemaker.	PER1 PER2	1.29e-06	2	40	2	18487196
Pubmed	Decoupling PER phosphorylation, stability and rhythmic expression from circadian clock function by abolishing PER-CK1 interaction.	PER1 PER2	1.29e-06	2	40	2	35810166
Pubmed	Cardiac atrial circadian rhythms in PERIOD2::LUCIFERASE and per1:luc mice: amplitude and phase responses to glucocorticoid signaling and medium treatment.	PER1 PER2	1.29e-06	2	40	2	23110090
Pubmed	Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment.	CLASP2 CLASP1	1.29e-06	2	40	2	16866869
Pubmed	Circadian Modulation of Neurons and Astrocytes Controls Synaptic Plasticity in Hippocampal Area CA1.	PER1 PER2	1.29e-06	2	40	2	33053337
Pubmed	Presence of multiple peripheral circadian oscillators in the tissues controlling voiding function in mice.	PER1 PER2	1.29e-06	2	40	2	24603368
Pubmed	The circadian clock protects against ionizing radiation-induced cardiotoxicity.	PER1 PER2	1.29e-06	2	40	2	31919902
Pubmed	Period gene expression in mouse endocrine tissues.	PER1 PER2	1.29e-06	2	40	2	12775559
Pubmed	Circadian time-dependent tumor suppressor function of period genes.	PER1 PER2	1.29e-06	2	40	2	19926612
Pubmed	Forebrain oscillators ticking with different clock hands.	PER1 PER2	1.29e-06	2	40	2	17996461
Pubmed	Circadian gene expression is resilient to large fluctuations in overall transcription rates.	PER1 PER2	1.29e-06	2	40	2	19078963
Pubmed	The circadian clock and tumor suppression by mammalian period genes.	PER1 PER2	1.29e-06	2	40	2	15817328
Pubmed	Low reproductive success in Per1 and Per2 mutant mouse females due to accelerated ageing?	PER1 PER2	1.29e-06	2	40	2	18367514
Pubmed	Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells.	CLASP2 CLASP1	1.29e-06	2	40	2	19701196
Pubmed	Temporal expression profiles of ceramide and ceramide-related genes in wild-type and mPer1/mPer2 double knockout mice.	PER1 PER2	1.29e-06	2	40	2	21773940
Pubmed	Analysis of common variations in tumor-suppressor genes on chr1p36 among Caucasian women with endometriosis.	ARID1A CHD5	1.29e-06	2	40	2	22910690
Pubmed	Homeostatic sleep regulation is preserved in mPer1 and mPer2 mutant mice.	PER1 PER2	1.29e-06	2	40	2	12383239
Pubmed	Segregation of expression of mPeriod gene homologs in neurons and glia: possible divergent roles of mPeriod1 and mPeriod2 in the brain.	PER1 PER2	1.29e-06	2	40	2	19477955
Pubmed	Mice lacking Period 1 and Period 2 circadian clock genes exhibit blue cone photoreceptor defects.	PER1 PER2	1.29e-06	2	40	2	23351077
Pubmed	Circadian clock genes Per1 and Per2 regulate the response of metabolism-associated transcripts to sleep disruption.	PER1 PER2	1.29e-06	2	40	2	23285241
Pubmed	Core circadian clock genes Per1 and Per2 regulate the rhythm in photoreceptor outer segment phagocytosis.	PER1 PER2	1.29e-06	2	40	2	34160105
Pubmed	Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.	RYR2 RYR3	1.29e-06	2	40	2	8898078
Pubmed	Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain.	CLASP2 CCDC88A	1.29e-06	2	40	2	24211587
Pubmed	Iron accumulation with age alters metabolic pattern and circadian clock gene expression through the reduction of AMP-modulated histone methylation.	PER1 PER2	1.29e-06	2	40	2	35460695
Pubmed	Robust circadian rhythmicity of Per1 and Per2 mutant mice in constant light, and dynamics of Per1 and Per2 gene expression under long and short photoperiods.	PER1 PER2	1.29e-06	2	40	2	12054191
Pubmed	Inhibition of light- or glutamate-induced mPer1 expression represses the phase shifts into the mouse circadian locomotor and suprachiasmatic firing rhythms.	PER1 PER2	1.29e-06	2	40	2	9920673
Pubmed	Endogenous circadian reporters reveal functional differences of PERIOD paralogs and the significance of PERIOD:CK1 stable interaction.	PER1 PER2	1.29e-06	2	40	2	36724252
Pubmed	mPer1 and mPer2 mutant mice show regular spatial and contextual learning in standardized tests for hippocampus-dependent learning.	PER1 PER2	1.29e-06	2	40	2	15959842
Pubmed	Influence of photoperiod duration and light-dark transitions on entrainment of Per1 and Per2 gene and protein expression in subdivisions of the mouse suprachiasmatic nucleus.	PER1 PER2	1.29e-06	2	40	2	19840112
Pubmed	Loss-of-function mutations with circadian rhythm regulator Per1/Per2 lead to premature ovarian insufficiency†.	PER1 PER2	1.29e-06	2	40	2	30452546
Pubmed	Differential effects of two period genes on the physiology and proteomic profiles of mouse anterior tibialis muscles.	PER1 PER2	1.29e-06	2	40	2	17202855
Pubmed	Light-induced phase shifts in mice lacking mPER1 or mPER2.	PER1 PER2	1.29e-06	2	40	2	12693867
Pubmed	Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization.	CLASP2 CLASP1	1.29e-06	2	40	2	10899121
Pubmed	The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.	RYR2 RYR3	1.29e-06	2	40	2	14550562
Pubmed	Circadian genes Period 1 and Period 2 in the nucleus accumbens regulate anxiety-related behavior.	PER1 PER2	1.29e-06	2	40	2	23039899
Pubmed	Cones are required for normal temporal responses to light of phase shifts and clock gene expression.	PER1 PER2	1.29e-06	2	40	2	20560710
Pubmed	Light responsiveness of clock genes, Per1 and Per2, in the olfactory bulb of mice.	PER1 PER2	1.29e-06	2	40	2	21624349
Pubmed	Circadian period 2: a missing beneficial factor in sickle cell disease by lowering pulmonary inflammation, iron overload, and mortality.	PER1 PER2	1.29e-06	2	40	2	31260634
Pubmed	Phase shifts and Per gene expression in mouse suprachiasmatic nucleus.	PER1 PER2	1.29e-06	2	40	2	12824769
Pubmed	Methamphetamine-induced, suprachiasmatic nucleus-independent circadian rhythms of activity and mPer gene expression in the striatum of the mouse.	PER1 PER2	1.29e-06	2	40	2	12372028
Pubmed	Circadian rhythms of hedonic drinking behavior in mice.	PER1 PER2	1.29e-06	2	40	2	28286126
Pubmed	Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins.	PER1 PER2	1.29e-06	2	40	2	26862173
Pubmed	Age and oestrus cycle-related changes in glucocorticoid excretion and wheel-running activity in female mice carrying mutations in the circadian clock genes Per1 and Per2.	PER1 PER2	1.29e-06	2	40	2	18786554
Pubmed	Physiological and Molecular Dissection of Daily Variance in Exercise Capacity.	PER1 PER2	1.29e-06	2	40	2	31006590
Pubmed	Per1/Per2 knockout Affects Spleen Immune Function in Elderly Mice via Inducing Spleen Lymphocyte Ferroptosis.	PER1 PER2	1.29e-06	2	40	2	36361751
Pubmed	Deficiency in PER proteins has no effect on the rate of spontaneous and radiation-induced carcinogenesis.	PER1 PER2	1.29e-06	2	40	2	24091726
Pubmed	A suprachiasmatic-independent circadian clock(s) in the habenula is affected by Per gene mutations and housing light conditions in mice.	PER1 PER2	1.29e-06	2	40	2	30242505
Pubmed	Deregulated expression of the Per1 and Per2 in human gliomas.	PER1 PER2	1.29e-06	2	40	2	20481271
Pubmed	Expression of the circadian clock genes Per1 and Per2 in sporadic and familial breast tumors.	PER1 PER2	1.29e-06	2	40	2	17971899
Pubmed	Stromal Expression of the Core Clock Gene Period 2 Is Essential for Tumor Initiation and Metastatic Colonization.	PER1 PER2	1.29e-06	2	40	2	33123539
Pubmed	Time-place learning and memory persist in mice lacking functional Per1 and Per2 clock genes.	PER1 PER2	1.29e-06	2	40	2	24336415
Pubmed	Distinct phase relationships between suprachiasmatic molecular rhythms, cerebral cortex molecular rhythms, and behavioral rhythms in early runner (CAST/EiJ) and nocturnal (C57BL/6J) mice.	PER1 PER2	1.29e-06	2	40	2	23024437
Pubmed	The circadian Per1 and Per2 genes influence alcohol intake, reinforcement, and blood alcohol levels.	PER1 PER2	1.29e-06	2	40	2	23608482
Pubmed	Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.	RYR2 RYR3	1.29e-06	2	40	2	14985349
Pubmed	Circadian rhythms in Per1, PER2 and Ca2+ of a solitary SCN neuron cultured on a microisland.	PER1 PER2	1.29e-06	2	40	2	31797953
Pubmed	Disruption of clock gene expression alters responses of the aryl hydrocarbon receptor signaling pathway in the mouse mammary gland.	PER1 PER2	1.29e-06	2	40	2	17715397
Pubmed	Host circadian behaviors exert only weak selective pressure on the gut microbiome under stable conditions but are critical for recovery from antibiotic treatment.	PER1 PER2	1.29e-06	2	40	2	36350921
Pubmed	Myeloid cell-specific disruption of Period1 and Period2 exacerbates diet-induced inflammation and insulin resistance.	PER1 PER2	1.29e-06	2	40	2	24770415
Pubmed	Rigid Cooperation of Per1 and Per2 proteins.	PER1 PER2	1.29e-06	2	40	2	27609640
Pubmed	Lack of food anticipation in Per2 mutant mice.	PER1 PER2	1.29e-06	2	40	2	17055980
Pubmed	Daily variation in global and local DNA methylation in mouse livers.	PER1 PER2	1.29e-06	2	40	2	25689298
Pubmed	Per1/Per2 Disruption Reduces Testosterone Synthesis and Impairs Fertility in Elderly Male Mice.	PER1 PER2	1.29e-06	2	40	2	35806403
Pubmed	Chronic circadian disturbance by a shortened light-dark cycle increases mortality.	PER1 PER2	1.29e-06	2	40	2	22154820
Pubmed	Differential expressions of mPer1 and mPer2 mRNAs under a skeleton photoperiod and a complete light-dark cycle.	PER1 PER2	1.29e-06	2	40	2	12531511
Pubmed	Circadian gene expression in the murine larynx.	PER1 PER2	1.29e-06	2	40	2	18346860
Pubmed	Expression profiles of PERIOD1, 2, and 3 in peripheral blood mononuclear cells from older subjects.	PER1 PER2	3.87e-06	3	40	2	19013183
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR2 RYR3	3.87e-06	3	40	2	18403125
Pubmed	PER1 interaction with GPX1 regulates metabolic homeostasis under oxidative stress.	PER1 PER2	3.87e-06	3	40	2	32896721
Pubmed	Human casein kinase Idelta phosphorylation of human circadian clock proteins period 1 and 2.	PER1 PER2	3.87e-06	3	40	2	11165242
Pubmed	Clock proteins and training modify exercise capacity in a daytime-dependent manner.	PER1 PER2	3.87e-06	3	40	2	34426495
Pubmed	Abnormal circadian locomotor rhythms and Per gene expression in six-month-old triple transgenic mice model of Alzheimer's disease.	PER1 PER2	3.87e-06	3	40	2	29626648
Pubmed	A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light.	PER1 PER2	3.87e-06	3	40	2	9428527
Pubmed	CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development.	CLASP2 CLASP1	3.87e-06	3	40	2	28285824
Pubmed	Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II-Dependent Hypertension in Mice.	PER1 PER2	3.87e-06	3	40	2	26781276
Pubmed	Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei.	PER1 PER2	3.87e-06	3	40	2	9427249
Pubmed	Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network.	CLASP2 CLASP1	3.87e-06	3	40	2	17543864
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR2 RYR3	3.87e-06	3	40	2	18434746
Pubmed	Association between polymorphisms in period genes and bone density in postmenopausal Korean women.	PER1 PER2	3.87e-06	3	40	2	24678593
Pubmed	Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations.	PER1 PER2	3.87e-06	3	40	2	27912059
Interaction	PER3 interactions	PER1 CCDC88A PER2	1.22e-05	24	38	3	int:PER3
Interaction	H2AP interactions	KNTC1 CLASP2 CLASP1 NCAPH	1.69e-05	82	38	4	int:H2AP
Interaction	RP2 interactions	TXNRD1 KNTC1 WDR36 NCAPH	3.02e-05	95	38	4	int:RP2
Interaction	CENPE interactions	CLASP2 CLASP1 PSMD14 NCAPH	4.65e-05	106	38	4	int:CENPE
Interaction	TOP3B interactions	PER1 GRAMD2A CLASP2 ABCA2 WDR36 PER2 ARID1A BCR PROM2 MFHAS1 CHD5	5.72e-05	1470	38	11	int:TOP3B
Cytoband	15q23	GRAMD2A NOX5	6.84e-04	44	40	2	15q23
Cytoband	Ensembl 112 genes in cytogenetic band chr1q43	EXO1 RYR2	1.35e-03	62	40	2	chr1q43
Cytoband	Ensembl 112 genes in cytogenetic band chr15q23	GRAMD2A NOX5	1.63e-03	68	40	2	chr15q23
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR2 RYR3	5.50e-06	3	25	2	287
GeneFamily	Dyneins, axonemal	DNAI1 DNAH1	2.46e-04	17	25	2	536
GeneFamily	PHD finger proteins	PHF20 PHF20L1 CHD5	2.53e-04	90	25	3	88
GeneFamily	Tudor domain containing	PHF20 PHF20L1	1.19e-03	37	25	2	780
GeneFamily	EF-hand domain containing	NOX5 RYR2 RYR3	3.31e-03	219	25	3	863
Coexpression	GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_UP	A2M CLASP2 PER2 NCAPH MFHAS1	1.21e-05	197	40	5	M9817
Coexpression	GSE13306_RA_VS_UNTREATED_TCONV_UP	DPAGT1 CLASP1 MFHAS1 SLC4A9 SCN4A	1.30e-05	200	40	5	M3234
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	TXNRD1 EXO1 DPAGT1 KNTC1 SLC4A4 NCAPH	3.10e-05	402	40	6	MM454
Coexpression	MCCLUNG_CREB1_TARGETS_DN	TXNRD1 CCDC88A PER2	8.63e-05	56	40	3	M3576
Coexpression	MCCLUNG_CREB1_TARGETS_DN	TXNRD1 CCDC88A PER2	1.06e-04	60	40	3	MM654
Coexpression	WINNEPENNINCKX_MELANOMA_METASTASIS_UP	EXO1 KNTC1 CLASP1 NCAPH	1.08e-04	162	40	4	M6387
Coexpression	GSE37534_PIOGLITAZONE_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP	MTG1 PHF20 CLASP1 PSMD14	1.76e-04	184	40	4	M8990
Coexpression	FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_DN	EXO1 KNTC1 MSH5 NCAPH	1.99e-04	190	40	4	M761
Coexpression	GSE45365_CD8A_DC_VS_CD11B_DC_UP	TXNRD1 WDR36 CLASP1 NCAPH	2.29e-04	197	40	4	M9997
Coexpression	GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_DN	EXO1 DPAGT1 KNTC1 NCAPH	2.33e-04	198	40	4	M8274
Coexpression	GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN	ASCC1 TXNRD1 EXO1 DPAGT1	2.33e-04	198	40	4	M4202
Coexpression	GSE25088_WT_VS_STAT6_KO_MACROPHAGE_DN	EXO1 CCDC88A AUNIP NCAPH	2.38e-04	199	40	4	M8031
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN	EXO1 DPAGT1 KNTC1 PSMD14	2.38e-04	199	40	4	M4525
Coexpression	HALLMARK_MITOTIC_SPINDLE	KNTC1 CCDC88A CLASP1 BCR	2.38e-04	199	40	4	M5893
Coexpression	GSE39022_LN_VS_SPLEEN_DC_UP	EXO1 DPAGT1 AUNIP TLR6	2.38e-04	199	40	4	M9017
Coexpression	GSE3982_BASOPHIL_VS_TH2_DN	DNAI1 MTG1 PER2 MFHAS1	2.38e-04	199	40	4	M5567
Coexpression	GSE3039_CD4_TCELL_VS_B2_BCELL_DN	TXNRD1 A2M MTG1 MFHAS1	2.42e-04	200	40	4	M6464
Coexpression	GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN	EXO1 DPAGT1 KNTC1 PSMD14	2.42e-04	200	40	4	M4593
Coexpression	GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_UP	TXNRD1 EXO1 WDR36 MFHAS1	2.42e-04	200	40	4	M8957
Coexpression	GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN	TXNRD1 EXO1 AUNIP PSMD14	2.42e-04	200	40	4	M4531
Coexpression	GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN	PER1 PHF20 BCR PSMD14	2.42e-04	200	40	4	M7019
Coexpression	GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	EXO1 DPAGT1 PSMD14 NCAPH	2.42e-04	200	40	4	M9120
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M SLC4A4 RYR2 RYR3 DNAH1	6.35e-07	184	40	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M SLC4A4 RYR2 RYR3 DNAH1	6.35e-07	184	40	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M SLC4A4 RYR2 RYR3 DNAH1	6.35e-07	184	40	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EXO1 AUNIP CCL27 NCAPH PROM2	8.89e-07	197	40	5	25bbe270d0897b9b1bd00d205f66efd1def81b99
ToppCell	droplet-Lung-nan-18m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO1 KNTC1 AUNIP NCAPH	1.54e-05	168	40	4	96f7411474edd673b8d3ee6b8a8bb185c246daaf
ToppCell	367C-Lymphocytic-ILC-ILC-2\|ILC / Donor, Lineage, Cell class and subclass (all cells)	A2M DPAGT1 PHF20	1.65e-05	55	40	3	7916216b3a24f9c6b966aa5392fc2bc43b3d2c4c
ToppCell	droplet-Lung-nan-18m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO1 KNTC1 AUNIP NCAPH	1.73e-05	173	40	4	20a20429aa898097d5ec4880ed64846558b5890f
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EXO1 KNTC1 AUNIP NCAPH	1.81e-05	175	40	4	a6913f992a1ea20b43e5adeca3ede3a6fda820ad
ToppCell	P28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EXO1 KNTC1 AUNIP NCAPH	2.07e-05	181	40	4	e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EXO1 KNTC1 AUNIP NCAPH	2.07e-05	181	40	4	74311aac2fe27dc02a9be3bc20e0c7ef1c239049
ToppCell	P28-Endothelial-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EXO1 KNTC1 AUNIP NCAPH	2.07e-05	181	40	4	2be3d44619adb25d339e7a27b500a56e07e8de01
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EXO1 KNTC1 AUNIP NCAPH	2.07e-05	181	40	4	cf13bf7a531a2d40f8d778629cf2431b684f65f3
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	EXO1 KNTC1 AUNIP NCAPH	2.16e-05	183	40	4	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5\|Striatum / BrainAtlas - Mouse McCarroll V32	EXO1 KNTC1 AUNIP NCAPH	2.16e-05	183	40	4	f20b0d71f857ac35868fd80531050ad8b6091716
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EXO1 KNTC1 AUNIP NCAPH	2.25e-05	185	40	4	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	A2M KNTC1 WDR36 CLASP1	2.30e-05	186	40	4	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	A2M CLASP2 RYR2 RYR3	2.40e-05	188	40	4	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO1 KNTC1 AUNIP NCAPH	2.40e-05	188	40	4	61ae7405ab56570409bf35382dc0a038e4137c15
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EXO1 KNTC1 AUNIP NCAPH	2.55e-05	191	40	4	15dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO1 KNTC1 AUNIP NCAPH	2.55e-05	191	40	4	239300ff76f2c855b2b04d3002461158be90a01b
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EXO1 KNTC1 AUNIP NCAPH	2.55e-05	191	40	4	45c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EXO1 KNTC1 CCDC88A NCAPH	2.66e-05	193	40	4	e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	EXO1 KNTC1 AUNIP NCAPH	2.77e-05	195	40	4	b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	EXO1 AUNIP PSMD14 NCAPH	2.94e-05	198	40	4	880f9817f5145f10f29fc05c5866090433532fe2
ToppCell	Sigmoid-Dendritic_cell-cycling_DCs\|Sigmoid / Region, Cell class and subclass	A2M AUNIP CAMKV NCAPH	3.00e-05	199	40	4	bd6f8c0f79e9a94cc0f8c6105d38851463de821c
ToppCell	Sigmoid-(5)_Dendritic_cell-(52)_cycling_DCs\|Sigmoid / shred on region, Cell_type, and subtype	A2M AUNIP CAMKV NCAPH	3.00e-05	199	40	4	8ee78a39729633bcbb3ab17e1dfaca33f38db569
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	EXO1 KNTC1 ARID1A NCAPH	3.05e-05	200	40	4	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	distal-Hematologic-Proliferating_Macrophage-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	EXO1 KNTC1 AUNIP NCAPH	3.05e-05	200	40	4	9c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	EXO1 KNTC1 CCDC88A NCAPH	3.05e-05	200	40	4	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	distal-3-Hematologic-Proliferating_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	EXO1 KNTC1 AUNIP NCAPH	3.05e-05	200	40	4	1b65c97e8123d0572d31525d6a10bc7f16857959
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	EXO1 KNTC1 ARID1A NCAPH	3.05e-05	200	40	4	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	PSB-critical-LOC-Lymphoid-Treg\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EXO1 KNTC1 AUNIP NCAPH	3.05e-05	200	40	4	3e3de496508efb2f95e5e8684f97687381e96493
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_2\|Striatum / BrainAtlas - Mouse McCarroll V32	EXO1 KNTC1 AUNIP	6.33e-05	86	40	3	2df674969383d93509ea9e201452cfda702fae40
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4\|Striatum / BrainAtlas - Mouse McCarroll V32	EXO1 KNTC1 AUNIP	6.33e-05	86	40	3	8ead39a100fa5aedf93a2206edd9828538f990a5
ToppCell	LPS-antiTNF-Unknown-Endothelial-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EXO1 RYR2 RYR3	2.25e-04	132	40	3	02491930097b75aaeedab9e8200711b0dc610944
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TRPV1 NCAPH SCN4A	2.51e-04	137	40	3	5cb84392e4483f50e09fb7395e2ec98f3eb6ecf3
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TRPV1 SLC4A4 NCAPH	2.91e-04	144	40	3	b622b605f7ec6083ec06c8ea0fd171e07c52f3de
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MSH5 SLC4A4 BCR	3.21e-04	149	40	3	aedbae2dffa1e880e5c6a146b6d5a135e7f54308
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	EXO1 KNTC1 AUNIP	3.47e-04	153	40	3	d7635f3d4831c02a94f53afc674847d5b51453be
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	EXO1 KNTC1 AUNIP	3.47e-04	153	40	3	e50d20f9e553b8c3e10e187770d8abe1a43d109e
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	EXO1 KNTC1 AUNIP	3.47e-04	153	40	3	54a941950bbb848077c7bd5726da9e4b3244bd38
ToppCell	Leuk-UTI-Lymphocyte-T_NK-MAIT\|Leuk-UTI / Disease, Lineage and Cell Type	ABCA2 AUNIP SLC4A4	3.47e-04	153	40	3	ac3a1d1b5bf6009df818fd757dad7382d95c60dc
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	EXO1 KNTC1 AUNIP	3.47e-04	153	40	3	69a8550418ba0fc908a84b3b85761abb6e8ca4c0
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRPV1 ARID1A NCAPH	3.68e-04	156	40	3	d411116d54add2d4fe649a97ac54cb94c085312f
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6\|TCGA-Kidney / Sample_Type by Project: Shred V9	EXO1 AUNIP NCAPH	3.68e-04	156	40	3	d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	A2M SLC4A9 RYR2	3.89e-04	159	40	3	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TGFB2 A2M SLC4A4	3.89e-04	159	40	3	57df5c9b678a15eb5e025e1a80de2e6769cc13d5
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO1 KNTC1 NCAPH	3.96e-04	160	40	3	8a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	EXO1 KNTC1 AUNIP	4.03e-04	161	40	3	0dd1401b4c990d49fccb702a9f9867590a58e203
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	EXO1 KNTC1 AUNIP	4.03e-04	161	40	3	b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	EXO1 ABCA2 CCL27	4.03e-04	161	40	3	bf4bfb416cb6ef43fc8cf0ffc2d7f0b6b42ab4da
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	EXO1 KNTC1 AUNIP	4.03e-04	161	40	3	efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	GRAMD2A CAMKV RYR3	4.03e-04	161	40	3	ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	EXO1 KNTC1 AUNIP	4.03e-04	161	40	3	28d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EXO1 KNTC1 NCAPH	4.18e-04	163	40	3	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 AUNIP NCAPH	4.18e-04	163	40	3	3f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	EXO1 KNTC1 NCAPH	4.25e-04	164	40	3	ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	EXO1 NCAPH RYR3	4.49e-04	167	40	3	315cde87eed2b42a1b9b068fae94caa10ec64c70
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 AUNIP NCAPH	4.64e-04	169	40	3	02fa66a91b8bd2bf971aec4f5ec58318b5bfdf14
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXO1 KNTC1 NCAPH	4.64e-04	169	40	3	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EXO1 KNTC1 NCAPH	4.64e-04	169	40	3	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 RYR3 DNAH1	4.64e-04	169	40	3	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	TGFB2 GRAMD2A RYR3	4.81e-04	171	40	3	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|metastatic_Lymph_Node / Location, Cell class and cell subclass	A2M KNTC1 DNAH1	4.89e-04	172	40	3	f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO1 MSH5 AUNIP	4.89e-04	172	40	3	e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCell	droplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EXO1 AUNIP NCAPH	4.97e-04	173	40	3	c399786aa25bdbe3394988db6955842b5b7e6b41
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	CHD5 RYR2 RYR3	4.97e-04	173	40	3	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EXO1 ABCA2 MSH5	5.06e-04	174	40	3	09b091e24317c3f7bac043f04762a533e30793de
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Control / Condition, Lineage and Cell class	A2M TLR6 NOX5	5.06e-04	174	40	3	4c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGFB2 EXO1 RYR2	5.06e-04	174	40	3	9f2e253694eb5860c00528fda31c305c6de8a2a1
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAI1 BCR RYR3	5.14e-04	175	40	3	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TGFB2 EXO1 RYR3	5.14e-04	175	40	3	9d09636a103daa8f622c3dbfd1f1536aaec3b6bb
ToppCell	(03)_Secretory-(4)_1wkpi\|(03)_Secretory / shred by cell type and Timepoint	PER1 GRAMD2A PER2	5.14e-04	175	40	3	06b52f85baa31b55bb31477244892b6da79fe2c9
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M ABCA2 SLC4A4	5.23e-04	176	40	3	5914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EXO1 KNTC1 NCAPH	5.23e-04	176	40	3	581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EXO1 TLR6 CCL27	5.23e-04	176	40	3	1510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EXO1 KNTC1 AUNIP	5.23e-04	176	40	3	9e719e6323597ecfc758c957256872cd4ae24d4d
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 AUNIP NCAPH	5.31e-04	177	40	3	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 AUNIP NCAPH	5.31e-04	177	40	3	f925a15d2162d166a5b60edac3517c6b2d6cfbea
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 AUNIP NCAPH	5.31e-04	177	40	3	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Myeloid / Condition, Lineage and Cell class	A2M TLR6 NOX5	5.31e-04	177	40	3	470f54fe2b21c7350ea471e02039461a3808f700
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TGFB2 EXO1 RYR3	5.40e-04	178	40	3	2a36475c260088f69f3b8c282d910e5eaa5c5c2d
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	A2M KNTC1 NCAPH	5.40e-04	178	40	3	462111b61f37338f97ac7dc6c7da1d4316b54445
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 AUNIP NCAPH	5.40e-04	178	40	3	c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXO1 KNTC1 AUNIP	5.49e-04	179	40	3	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KNTC1 MSH5 NCAPH	5.49e-04	179	40	3	df4d0b2fe47d2c7def729b3217cb01ced01495ff
ToppCell	Control-Developping_Plasmablast\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	EXO1 AUNIP NCAPH	5.49e-04	179	40	3	9383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXO1 KNTC1 NCAPH	5.58e-04	180	40	3	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EXO1 KNTC1 NCAPH	5.58e-04	180	40	3	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSH5 CAMKV BCR	5.67e-04	181	40	3	d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M TRPV1 ABCA2	5.67e-04	181	40	3	12ff56fa2949c8d53360cdf2cacfd326e65b54aa
ToppCell	Healthy_Control-Lymphoid-T-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	EXO1 KNTC1 AUNIP	5.67e-04	181	40	3	ac1ee313910c05b1b3cb497bae14565464919c21
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSH5 CAMKV BCR	5.67e-04	181	40	3	e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 AUNIP NCAPH	5.76e-04	182	40	3	fe46819c153a81911864473badc794f243705f98
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|World / disease group, cell group and cell class (v2)	EXO1 AUNIP NCAPH	5.76e-04	182	40	3	9adf90bb2808f234d53b89ca0ae07380478204ad
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TGFB2 EXO1 RYR3	5.76e-04	182	40	3	d3a037268f026eb2f84428b1821022503cef7756
ToppCell	severe-multiplets\|World / disease stage, cell group and cell class	PER1 EXO1 NCAPH	5.76e-04	182	40	3	5e30ec7120a988d9ee3000513e1209618f28f5f9
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TGFB2 SLC4A4 RYR2	5.76e-04	182	40	3	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 AUNIP NCAPH	5.76e-04	182	40	3	3948422707d6d5e021bcd7158e2eb69143613f62
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 AUNIP NCAPH	5.76e-04	182	40	3	b1e66ccd5f33b4801f1cafddf97f5fc0c6dba8d1
Drug	CAS 64485-93-4	PER1 PHF20 PER2 NCAPH	1.60e-06	50	39	4	CID000002631
Drug	etridiazole	A2M RYR2 RYR3 SCN4A	1.60e-06	50	39	4	CID000017432
Drug	AC1NS0C1	PER1 CCL27 NOX5	3.11e-06	17	39	3	CID005326326
Drug	AC1MXB9R	PER1 PHF20 PER2 NCAPH	4.91e-06	66	39	4	CID000002172
Drug	Lowicryl HM20	DNAI1 SLC4A4 SLC4A9	8.04e-06	23	39	3	CID000174488
Drug	2-hydroxycarbazole	RYR2 RYR3	8.57e-06	3	39	2	CID000093551
Drug	cis-diammineplatinum(II	RYR2 RYR3	8.57e-06	3	39	2	CID000159790
Drug	2-hydroxyheptanoic acid	RYR2 RYR3	8.57e-06	3	39	2	CID002750949
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR2 RYR3	8.57e-06	3	39	2	CID005748312
Drug	8N3-cADPR	RYR2 RYR3	8.57e-06	3	39	2	CID000127713
Drug	aminodantrolene	RYR2 RYR3	8.57e-06	3	39	2	CID009570289
Drug	T0702	TRPV1 RYR2 RYR3	1.04e-05	25	39	3	CID000005908
Drug	Rolipram [61413-54-5]; Up 200; 14.6uM; HL60; HT_HG-U133A	PER1 ABCA2 TLR6 ARID1A CCL27	1.71e-05	189	39	5	3072_UP
Drug	PCB74	RYR2 RYR3	1.71e-05	4	39	2	CID000036218
Drug	148504-47-6	RYR2 RYR3	1.71e-05	4	39	2	CID006444275
Drug	SC 38249	RYR2 RYR3	1.71e-05	4	39	2	CID000134834
Drug	AC1L1U7A	RYR2 RYR3	1.71e-05	4	39	2	CID000035682
Drug	Pseudopelletierine hydrochloride [6164-62-1]; Down 200; 21uM; HL60; HG-U133A	CCDC88A PER2 PHF20L1 ARID1A CLASP1	1.89e-05	193	39	5	1774_DN
Drug	Finasteride [98319-26-7]; Down 200; 10.8uM; HL60; HT_HG-U133A	A2M PER1 TRPV1 PER2 RYR2	1.94e-05	194	39	5	2206_DN
Drug	Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A	PER1 MTG1 CLASP2 ABCA2 CLASP1	1.94e-05	194	39	5	7354_DN
Drug	Dantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A	TGFB2 MTG1 TRPV1 ABCA2 PHF20	1.94e-05	194	39	5	3867_DN
Drug	Testosterone propionate [57-85-2]; Down 200; 11.6uM; PC3; HT_HG-U133A	CCDC88A PER2 ARID1A MFHAS1 RYR2	1.99e-05	195	39	5	4676_DN
Drug	sulfamide	PER1 SLC4A4 PER2	2.02e-05	31	39	3	CID000082267
Drug	Guaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A	ABCA2 PHF20 PER2 CCL27 RYR2	2.09e-05	197	39	5	3431_UP
Drug	Phenylephrine	TGFB2 PER1 TRPV1 PER2 CCL27 NOX5 MFHAS1	2.11e-05	505	39	7	ctd:D010656
Drug	Deoxycorticosterone [64-85-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A	A2M ABCA2 SLC4A4 PER2 CHD5	2.14e-05	198	39	5	6476_UP
Drug	Thiethylperazine malate [52239-63-1]; Up 200; 6uM; HL60; HT_HG-U133A	TRPV1 ABCA2 CAMKV BCR NOX5	2.14e-05	198	39	5	6154_UP
Drug	Naphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; PC3; HT_HG-U133A	ABCA2 ARID1A CCL27 CAMKV SCN4A	2.14e-05	198	39	5	6604_UP
Drug	IC261	TGFB2 DNAI1 PER2 DNAH1	2.18e-05	96	39	4	CID000003674
Drug	borate	TRPV1 SLC4A4 RYR2 RYR3	2.36e-05	98	39	4	CID000007628
Drug	H2DIDS	DPAGT1 SLC4A4 SLC4A9	2.45e-05	33	39	3	CID000115184
Drug	Freund's Adjuvant	TGFB2 A2M TRPV1 PER2 DNAH1	2.77e-05	209	39	5	ctd:D005620
Drug	1,2-dichlorohexafluorocyclobutane	RYR2 RYR3 SCN4A	3.47e-05	37	39	3	CID000009643
Drug	MBED	RYR2 RYR3	4.27e-05	6	39	2	CID000129958
Drug	chloro-m-cresol	RYR2 RYR3	4.27e-05	6	39	2	CID000012008
Drug	AC1O528X	RYR2 RYR3	4.27e-05	6	39	2	CID006475857
Drug	NSC114784	RYR2 RYR3	4.27e-05	6	39	2	CID000419425
Drug	AC1L1GTT	PER2 CAMKV RYR2 RYR3 SCN4A	4.66e-05	233	39	5	CID000003837
Drug	noradrealine	TGFB2 PER1 SLC4A4 PER2 NOX5 RYR2 RYR3	4.82e-05	575	39	7	CID000000951
Drug	AC1Q6X9N	DNAI1 CCL27 NOX5	5.09e-05	42	39	3	CID000072205
Drug	AC1L1E3B	PER1 PHF20 PER2	5.86e-05	44	39	3	CID000002622
Drug	Azumoleno	RYR2 RYR3	5.97e-05	7	39	2	CID000056259
Drug	Br2BAPTA	RYR2 RYR3	5.97e-05	7	39	2	CID003081001
Drug	[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate	RYR2 RYR3	5.97e-05	7	39	2	CID009547999
Drug	4,4'-dithiodipyridine	A2M RYR2 RYR3	6.27e-05	45	39	3	CID000075846
Drug	AC1L1IZE	DNAI1 RYR2 RYR3 DNAH1	7.36e-05	131	39	4	CID000004799
Drug	brotizolam	PER1 PER2	7.95e-05	8	39	2	CID000002451
Drug	Mi-1	PER1 PER2	7.95e-05	8	39	2	CID000198746
Drug	Trp-Trp	KNTC1 RYR2 RYR3	8.11e-05	49	39	3	CID000088656
Drug	C11536	PER1 PER2 PSMD14	9.14e-05	51	39	3	CID000443249
Drug	cobalt phthalocyanine	PER1 NOX5	1.02e-04	9	39	2	CID000076829
Drug	N-methyl-DL-aspartic acid	TGFB2 PER1 PER2 CAMKV RYR2 RYR3 SCN4A	1.09e-04	655	39	7	CID000004376
Drug	Sulcrate	A2M KNTC1 ABCA2 NOX5	1.18e-04	148	39	4	CID006398525
Drug	pentacene	PHF20 CCL27	1.28e-04	10	39	2	CID000008671
Drug	showdomycin	DPAGT1 NOX5	1.28e-04	10	39	2	CID000028032
Drug	PCB 95	RYR2 RYR3	1.28e-04	10	39	2	CID000038012
Drug	Dasatinib	TGFB2 A2M EXO1 KNTC1 BCR NCAPH	1.50e-04	478	39	6	ctd:D000069439
Drug	PCB 66	RYR2 RYR3	1.56e-04	11	39	2	CID000036185
Drug	R 478	RYR2 RYR3	1.56e-04	11	39	2	CID000084223
Drug	8-amino-cADPR	RYR2 RYR3	1.56e-04	11	39	2	CID003081323
Drug	fulvestrant	TXNRD1 PER1 TRPV1 ARID1A PSMD14 NCAPH	1.61e-04	484	39	6	ctd:C070081
Drug	Ryanodine	RYR2 RYR3	1.87e-04	12	39	2	ctd:D012433
Drug	nonivamide	TRPV1 NOX5	1.87e-04	12	39	2	CID000002998
Drug	glutamate	PER1 TRPV1 SLC4A4 PER2 PSMD14 RYR2 RYR3 SCN4A	1.89e-04	962	39	8	CID000000611
Drug	strontium	KNTC1 RYR2 RYR3	2.16e-04	68	39	3	CID000104798
Drug	AC1LCJM3	TRPV1 SCN4A	2.20e-04	13	39	2	CID000631640
Drug	pioglitazone	TGFB2 PER2 NOX5 RYR2 RYR3	2.25e-04	326	39	5	CID000004829
Drug	TMB-8	TGFB2 NOX5 RYR2 RYR3	2.30e-04	176	39	4	CID000005494
Drug	flecainide	RYR2 RYR3 SCN4A	2.45e-04	71	39	3	CID000003355
Drug	iberin	TXNRD1 TLR6	2.57e-04	14	39	2	ctd:C082585
Drug	Fmoc	SLC4A4 SCN4A	2.57e-04	14	39	2	CID000034367
Drug	BCECF	DNAI1 SLC4A4 SLC4A9	2.66e-04	73	39	3	CID004241719
Drug	forskolin from Coleus forskohlii	TGFB2 PER1 TRPV1 SLC4A4 PER2 RYR2 RYR3 SCN4A	2.68e-04	1013	39	8	CID000003413
Drug	Pizotifen malate [5189-11-7]; Up 200; 9.4uM; PC3; HT_HG-U133A	TGFB2 PER1 ABCA2 MFHAS1	2.78e-04	185	39	4	5072_UP
Drug	Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; PC3; HT_HG-U133A	TGFB2 A2M SLC4A4 RYR2	2.89e-04	187	39	4	4589_UP
Drug	FPL 64176	RYR2 RYR3	2.96e-04	15	39	2	CID000003423
Drug	Gvapspat amide	RYR2 RYR3	2.96e-04	15	39	2	CID000125015
Drug	CT 0	PER1 PER2	2.96e-04	15	39	2	CID002255489
Drug	AC1MQSA8	DNAI1 CCDC88A SLC4A4	3.00e-04	76	39	3	CID003481670
Drug	Benzethonium chloride [121-54-0]; Down 200; 9uM; HL60; HT_HG-U133A	PER1 TRPV1 ABCA2 RYR2	3.01e-04	189	39	4	2508_DN
Drug	2-propylpentanoic acid; Up 200; 500uM; HL60; HT_HG-U133A	TRPV1 SLC4A4 CCL27 CAMKV	3.08e-04	190	39	4	6199_UP
Drug	geldanamycin; Down 200; 1uM; PC3; HT_HG-U133A	EXO1 TRPV1 PHF20 ARID1A	3.08e-04	190	39	4	4452_DN
Drug	propofol	TRPV1 RYR2 RYR3 SCN4A	3.14e-04	191	39	4	CID000004943
Drug	Amrinone [60719-84-8]; Down 200; 21.4uM; PC3; HT_HG-U133A	TGFB2 ABCA2 CCDC88A CCL27	3.26e-04	193	39	4	4488_DN
Drug	CP-690334-01 [459212-38-5]; Down 200; 1uM; PC3; HT_HG-U133A	TRPV1 ABCA2 SLC4A4 PER2	3.33e-04	194	39	4	3826_DN
Drug	(-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A	PER1 SLC4A4 PER2 RYR2	3.33e-04	194	39	4	6833_UP
Drug	Hydrocotarnine hydrobromide [5985-00-2]; Up 200; 13.2uM; MCF7; HT_HG-U133A	CCDC88A PER2 CCL27 NOX5	3.33e-04	194	39	4	6827_UP
Drug	L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; PC3; HT_HG-U133A	TLR6 SLC4A4 CAMKV RYR2	3.33e-04	194	39	4	5056_UP
Drug	Dinoprost trometamol [38362-01-5]; Up 200; 8.4uM; PC3; HT_HG-U133A	TGFB2 ABCA2 SLC4A4 CCL27	3.33e-04	194	39	4	6308_UP
Drug	N-cyclopentyl-N-cyclobutylformamide	NOX5 RYR2 RYR3	3.36e-04	79	39	3	CID005287890
Drug	Tolbutamide [64-77-7]; Up 200; 14.8uM; PC3; HT_HG-U133A	TLR6 CCL27 CHD5 RYR2	3.39e-04	195	39	4	3804_UP
Drug	Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; PC3; HT_HG-U133A	TGFB2 PHF20 PER2 ARID1A	3.39e-04	195	39	4	6626_UP
Drug	Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A	TGFB2 PHF20 ARID1A RYR2	3.39e-04	195	39	4	4748_DN
Drug	Pentamidine isethionate [140-64-7]; Down 200; 6.8uM; MCF7; HT_HG-U133A	TGFB2 PHF20 SLC4A4 ARID1A	3.39e-04	195	39	4	4396_DN
Drug	Khellin [82-02-0]; Down 200; 15.4uM; HL60; HG-U133A	ASCC1 CCDC88A PHF20L1 MFHAS1	3.39e-04	195	39	4	2004_DN
Drug	Nitrendipine [39562-70-4]; Up 200; 11uM; MCF7; HT_HG-U133A	TGFB2 A2M PHF20 SLC4A4	3.46e-04	196	39	4	6464_UP
Drug	Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; PC3; HT_HG-U133A	CCDC88A SLC4A4 ARID1A BCR	3.46e-04	196	39	4	2101_UP
Drug	Parbendazole [14255-87-9]; Up 200; 16.2uM; PC3; HT_HG-U133A	TGFB2 PER1 ABCA2 SLC4A4	3.46e-04	196	39	4	4535_UP
Drug	Mifepristone [84371-65-3]; Down 200; 9.4uM; PC3; HT_HG-U133A	ASCC1 TGFB2 MTG1 TRPV1	3.46e-04	196	39	4	5827_DN
Drug	Hymecromone [90-33-5]; Up 200; 22.8uM; MCF7; HT_HG-U133A	SLC4A4 PER2 NOX5 CHD5	3.46e-04	196	39	4	3383_UP
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR2 RYR3	5.37e-06	3	40	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR2 RYR3	5.37e-06	3	40	2	DOID:8545 (implicated_via_orthology)
Disease	Myeloid Leukemia, Chronic	PER1 PER2 BCR	8.23e-06	29	40	3	C0023473
Disease	Colorectal Neoplasms	TXNRD1 EXO1 DPAGT1 ARID1A CHD5	3.54e-05	277	40	5	C0009404
Disease	Glaucoma	TGFB2 SLC4A4	6.41e-05	9	40	2	C0017601
Disease	anemia (implicated_via_orthology)	SLC4A4 SLC4A9	1.86e-04	15	40	2	DOID:2355 (implicated_via_orthology)
Disease	Myasthenic Syndromes, Congenital, Slow Channel	DPAGT1 SCN4A	2.12e-04	16	40	2	C0751885
Disease	Congenital Myasthenic Syndromes, Postsynaptic	DPAGT1 SCN4A	2.41e-04	17	40	2	C0751883
Disease	Congenital Myasthenic Syndromes, Presynaptic	DPAGT1 SCN4A	3.02e-04	19	40	2	C0751884
Disease	Colorectal Carcinoma	TXNRD1 PER1 EXO1 DPAGT1 ARID1A CHD5	3.42e-04	702	40	6	C0009402
Disease	Malignant mesothelioma	TGFB2 CCL27 RYR2	4.39e-04	109	40	3	C0345967
Disease	Myasthenic Syndromes, Congenital	DPAGT1 SCN4A	4.85e-04	24	40	2	C0751882
Disease	systemic mastocytosis	ABCA2 MSH5	5.27e-04	25	40	2	MONDO_0016586
Disease	Liver carcinoma	A2M EXO1 MSH5 ARID1A NCAPH	5.88e-04	507	40	5	C2239176
Disease	suicidal ideation	CLASP2 WDR36	7.11e-04	29	40	2	EFO_0004320
Disease	Kartagener Syndrome	DNAI1 DNAH1	1.04e-03	35	40	2	C0022521
Disease	Polynesian Bronchiectasis	DNAI1 DNAH1	1.04e-03	35	40	2	C4317124
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	DNAI1 DNAH1	1.04e-03	35	40	2	C4551906
Disease	Burkitt Lymphoma	ARID1A BCR	1.10e-03	36	40	2	C0006413
Disease	Primary ciliary dyskinesia	DNAI1 DNAH1	1.10e-03	36	40	2	cv:C0008780
Disease	Mastocytosis	ABCA2 MSH5	1.29e-03	39	40	2	EFO_0009001

Protein segments in the cluster

Peptide	Gene	Start	Entry
VKLLLMPAKHQPDLL	SLC4A9	861	Q96Q91
LHGTLPKLNFGMLRK	CCL27	96	Q9Y4X3
QIKKLHDLLGPHMLR	CHD5	916	Q8TDI0
HLEALLLPMKPLKAA	BCR	516	P11274
QNPKKLHLTIGMLVL	ASCC1	201	Q8N9N2
GHIISLKLSPNLRKM	DNAI1	651	Q9UI46
MGKNKLLHPSLVLLL	A2M	1	P01023
LTLLIHGSPMDKLKF	NOX5	86	Q96PH1
MSKHPGLLLILGKLI	ARID1A	2001	O14497
VQPRLKLLLMGHKAA	MFHAS1	406	Q9Y4C4
IEPLLKNMALHLKRL	CCDC88A	186	Q3V6T2
MTLINLLLKVLGPIH	DPAGT1	361	Q9H3H5
ETLGLKPHLLVLNKM	MTG1	71	Q9BT17
DRPLMLAIHKKILQL	PER1	401	O15534
PLMLAIHKKILQSGG	PER2	376	O15055
HPKLLAKALEMVPLL	KNTC1	1491	P50748
HLLDMLLTNKKPVLC	DNAH1	2211	Q9P2D7
IGILKMVKHPNILQL	CAMKV	71	Q8NCB2
LGLLVHLMTSNPKIL	ABCA2	446	Q9BZC7
KKHKMARLLPNGLAI	GRAMD2A	136	Q8IUY3
VPLLNEHAKMPLKLL	RYR2	2596	Q92736
MFQLLIPLLLALKGH	PRSS51	1	A0A1B0GVH4
QTHLIKPGTKMLTLL	AUNIP	26	Q9H7T9
LALLKMLKHGRAGVP	PSMD14	36	O00487
LPQLKRHIKQLLIDM	PHF20L1	991	A8MW92
LPQLKHCIKQLLMDL	PHF20	986	Q9BVI0
GHIKNVPLILKRMKL	MSH5	311	O43196
LGLLHGKILSPKDIM	SCN4A	841	P35499
KFVNMLLSHGIKPIL	EXO1	61	Q9UQ84
QLHLKPGTRLLKMAQ	NCAPH	521	Q15003
PHLAQLTGSKMKLLN	CLASP1	1501	Q7Z460
KPHLSQLTGSKMKLL	CLASP2	1256	O75122
RKKNSGKTPHLLLML	TGFB2	271	P61812
PKKLMHQAALLGQAL	TXNRD1	216	Q16881
NEILMLGAKLHPTLK	TRPV1	311	Q8NER1
MKHTLALLAPLLGLG	PROM2	1	Q8N271
LIVAALKKMLPIGLN	RYR3	3366	Q15413
LGLSAMKLQKLDLLP	TLR6	151	Q9Y2C9
MKLQKLDLLPIAHLH	TLR6	156	Q9Y2C9
LKLLLMPLKHQPDFI	SLC4A4	926	Q9Y6R1
LKLHLKMLPSEPVLL	WDR36	901	Q8NI36