Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	chromatin binding	RAD21L1 NCOA3 ARID1B KAT6B ADNP HOXD10 NFAT5 POLR3A HDAC2 KAT6A ZIC2 CBX2	6.75e-09	739	38	12	GO:0003682
GeneOntologyMolecularFunction	transcription coactivator activity	TRERF1 NCOA3 ARID1B WWOX KAT6B MAML3 KAT6A	1.46e-06	303	38	7	GO:0003713
GeneOntologyMolecularFunction	endopeptidase inhibitor activity	GBP2 SERPINE3 SERPINA6 SERPINA7 NAIP	2.22e-05	180	38	5	GO:0004866
GeneOntologyMolecularFunction	peptidase inhibitor activity	GBP2 SERPINE3 SERPINA6 SERPINA7 NAIP	2.67e-05	187	38	5	GO:0030414
GeneOntologyMolecularFunction	endopeptidase regulator activity	GBP2 SERPINE3 SERPINA6 SERPINA7 NAIP	3.77e-05	201	38	5	GO:0061135
GeneOntologyMolecularFunction	transcription coregulator activity	TRERF1 NCOA3 ARID1B WWOX KAT6B MAML3 KAT6A	7.97e-05	562	38	7	GO:0003712
GeneOntologyMolecularFunction	peptidase regulator activity	GBP2 SERPINE3 SERPINA6 SERPINA7 NAIP	1.20e-04	257	38	5	GO:0061134
GeneOntologyMolecularFunction	histone acetyltransferase activity	NCOA3 KAT6B KAT6A	1.24e-04	51	38	3	GO:0004402
GeneOntologyMolecularFunction	histone H3K14 acetyltransferase activity	KAT6B KAT6A	1.26e-04	9	38	2	GO:0036408
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	NCOA3 KAT6B KAT6A	1.56e-04	55	38	3	GO:0061733
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	NCOA3 KAT6B KAT6A	2.02e-04	60	38	3	GO:0034212
GeneOntologyMolecularFunction	RNA polymerase binding	NCOA3 GSG1 SCAF4	2.56e-04	65	38	3	GO:0070063
GeneOntologyMolecularFunction	histone H3 acetyltransferase activity	KAT6B KAT6A	3.65e-04	15	38	2	GO:0010484
GeneOntologyMolecularFunction	N-acetyltransferase activity	NCOA3 KAT6B KAT6A	4.38e-04	78	38	3	GO:0008080
GeneOntologyMolecularFunction	histone modifying activity	NCOA3 KAT6B HDAC2 KAT6A	9.16e-04	229	38	4	GO:0140993
GeneOntologyMolecularFunction	N-acyltransferase activity	NCOA3 KAT6B KAT6A	9.59e-04	102	38	3	GO:0016410
GeneOntologyMolecularFunction	acetyltransferase activity	NCOA3 KAT6B KAT6A	1.01e-03	104	38	3	GO:0016407
GeneOntologyMolecularFunction	serine-type endopeptidase inhibitor activity	SERPINE3 SERPINA6 SERPINA7	1.04e-03	105	38	3	GO:0004867
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	TRERF1 NCOA3 ARID1B WIPI1 WWOX KAT6B MAML3 KAT6A	1.30e-03	1160	38	8	GO:0030674
GeneOntologyMolecularFunction	enzyme inhibitor activity	GBP2 SERPINE3 SERPINA6 SERPINA7 NAIP	1.33e-03	435	38	5	GO:0004857
GeneOntologyMolecularFunction	nuclear androgen receptor binding	NCOA3 WIPI1	1.79e-03	33	38	2	GO:0050681
GeneOntologyMolecularFunction	RNA polymerase II complex binding	NCOA3 SCAF4	2.50e-03	39	38	2	GO:0000993
GeneOntologyMolecularFunction	transcription factor binding	TRERF1 NCOA3 WIPI1 NFAT5 HDAC2 KAT6A	2.78e-03	753	38	6	GO:0008134
GeneOntologyMolecularFunction	RNA polymerase core enzyme binding	NCOA3 SCAF4	3.32e-03	45	38	2	GO:0043175
GeneOntologyMolecularFunction	molecular adaptor activity	TRERF1 NCOA3 ARID1B WIPI1 WWOX KAT6B MAML3 KAT6A	3.47e-03	1356	38	8	GO:0060090
GeneOntologyMolecularFunction	nuclear estrogen receptor binding	NCOA3 WIPI1	4.57e-03	53	38	2	GO:0030331
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	TRERF1 NCOA3 WIPI1 HDAC2 KAT6A	4.69e-03	582	38	5	GO:0140297
GeneOntologyMolecularFunction	molecular function inhibitor activity	GBP2 SERPINE3 SERPINA6 SERPINA7 NAIP	5.18e-03	596	38	5	GO:0140678
GeneOntologyMolecularFunction	nuclear receptor binding	TRERF1 NCOA3 WIPI1	5.36e-03	187	38	3	GO:0016922
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	NCOA3 CPHXL ADNP HOXD10 NFAT5 CPHXL2 HDAC2 ZIC2	5.41e-03	1459	38	8	GO:0000977
GeneOntologyMolecularFunction	nuclear receptor coactivator activity	TRERF1 NCOA3	6.01e-03	61	38	2	GO:0030374
GeneOntologyMolecularFunction	basal RNA polymerase II transcription machinery binding	NCOA3 SCAF4	7.01e-03	66	38	2	GO:0001099
GeneOntologyMolecularFunction	basal transcription machinery binding	NCOA3 SCAF4	7.01e-03	66	38	2	GO:0001098
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	TRERF1 NCOA3 WIPI1 HDAC2	7.90e-03	417	38	4	GO:0061629
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	NCOA3 KAT6B KAT6A	1.04e-02	238	38	3	GO:0016747
GeneOntologyCellularComponent	MOZ/MORF histone acetyltransferase complex	KAT6B KAT6A	6.72e-05	7	38	2	GO:0070776
GeneOntologyCellularComponent	transcription regulator complex	TRERF1 NCOA3 WWOX ADNP HOXD10 NFAT5 HDAC2	8.65e-05	596	38	7	GO:0005667
GeneOntologyCellularComponent	H3 histone acetyltransferase complex	KAT6B KAT6A	8.95e-05	8	38	2	GO:0070775
GeneOntologyCellularComponent	nuclear protein-containing complex	TRERF1 NCOA3 ARID1B WWOX ADNP POLR3A HDAC2 MAD1L1 CBX2	6.49e-04	1377	38	9	GO:0140513
GeneOntologyCellularComponent	chromatin	NCOA3 ARID1B KAT6B ADNP HOXD10 NFAT5 HDAC2 KAT6A CBX2	1.09e-03	1480	38	9	GO:0000785
HumanPheno	Abnormality of the philtrum	ARID1B WWOX KAT6B ADNP CERT1 POLR3A SCAF4 KAT6A ZIC2 ALG13	1.16e-05	726	16	10	HP:0000288
HumanPheno	Upslanted palpebral fissure	CACNA1G ARID1B WWOX ADNP CERT1 POLR3A ZIC2	3.28e-05	333	16	7	HP:0000582
HumanPheno	Abnormal external nose morphology	ARID1B WWOX KAT6B ADNP CERT1 POLR3A SCAF4 KAT6A ZIC2 ALG13	9.45e-05	916	16	10	HP:0010938
HumanPheno	Anteverted nares	ARID1B WWOX ADNP CERT1 POLR3A KAT6A ZIC2 ALG13	1.16e-04	559	16	8	HP:0000463
HumanPheno	Upturned nose	ARID1B WWOX ADNP CERT1 POLR3A KAT6A ZIC2 ALG13	1.16e-04	559	16	8	HP:0000427
HumanPheno	Abnormal nostril morphology	ARID1B WWOX ADNP CERT1 POLR3A KAT6A ZIC2 ALG13	1.41e-04	575	16	8	HP:0005288
HumanPheno	Long philtrum	ARID1B WWOX KAT6B ADNP POLR3A SCAF4 ALG13	1.67e-04	429	16	7	HP:0000343
HumanPheno	Abnormal upper lip morphology	ARID1B WWOX KAT6B ADNP CERT1 POLR3A SCAF4 KAT6A ZIC2 ALG13	1.72e-04	980	16	10	HP:0000177
Domain	Serpin_CS	SERPINE3 SERPINA6 SERPINA7	3.14e-05	32	36	3	IPR023795
Domain	MOZ_SAS	KAT6B KAT6A	3.60e-05	5	36	2	PF01853
Domain	HAT_MYST-type	KAT6B KAT6A	3.60e-05	5	36	2	IPR002717
Domain	MYST_HAT	KAT6B KAT6A	3.60e-05	5	36	2	PS51726
Domain	Serpin_dom	SERPINE3 SERPINA6 SERPINA7	4.49e-05	36	36	3	IPR023796
Domain	SERPIN	SERPINE3 SERPINA6 SERPINA7	4.88e-05	37	36	3	SM00093
Domain	SERPIN	SERPINE3 SERPINA6 SERPINA7	4.88e-05	37	36	3	PS00284
Domain	Serpin	SERPINE3 SERPINA6 SERPINA7	5.30e-05	38	36	3	PF00079
Domain	Serpin_fam	SERPINE3 SERPINA6 SERPINA7	5.73e-05	39	36	3	IPR000215
Domain	H15	KAT6B KAT6A	2.78e-04	13	36	2	SM00526
Domain	H15	KAT6B KAT6A	2.78e-04	13	36	2	PS51504
Domain	Histone_H1/H5_H15	KAT6B KAT6A	3.24e-04	14	36	2	IPR005818
Domain	-	KAT6B KAT6A	2.69e-03	40	36	2	3.40.630.30
Domain	Acyl_CoA_acyltransferase	KAT6B KAT6A	3.39e-03	45	36	2	IPR016181
Domain	PHD	KAT6B KAT6A	9.18e-03	75	36	2	PF00628
Domain	Znf_PHD-finger	KAT6B KAT6A	1.01e-02	79	36	2	IPR019787
Domain	WHTH_DNA-bd_dom	RAD21L1 KAT6B KAT6A	1.12e-02	242	36	3	IPR011991
Domain	PHD	KAT6B KAT6A	1.27e-02	89	36	2	SM00249
Domain	Znf_PHD	KAT6B KAT6A	1.33e-02	91	36	2	IPR001965
Domain	ZF_PHD_2	KAT6B KAT6A	1.44e-02	95	36	2	PS50016
Domain	ZF_PHD_1	KAT6B KAT6A	1.47e-02	96	36	2	PS01359
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	ARID1B KAT6B HDAC2 KAT6A CBX2	7.83e-07	157	38	5	30186101
Pubmed	ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B.	KAT6B KAT6A	1.16e-06	2	38	2	39505971
Pubmed	NCOA3, a new fusion partner for MOZ/MYST3 in M5 acute myeloid leukemia.	NCOA3 KAT6A	1.16e-06	2	38	2	17805331
Pubmed	Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease.	KAT6B KAT6A	1.16e-06	2	38	2	27185879
Pubmed	Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins.	SERPINA6 SERPINA7	1.16e-06	2	38	2	21325280
Pubmed	The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.	KAT6B KAT6A	1.16e-06	2	38	2	24150941
Pubmed	MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.	KAT6B KAT6A	3.48e-06	3	38	2	36754959
Pubmed	Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin.	KAT6B KAT6A	3.48e-06	3	38	2	23063713
Pubmed	RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.	ARID1B EIF4G3 ADNP	4.31e-06	29	38	3	36800290
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TRERF1 NCOA3 RESF1 WWOX ADNP HDAC2	5.80e-06	418	38	6	34709266
Pubmed	Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF).	KAT6B KAT6A	6.96e-06	4	38	2	21880731
Pubmed	The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60.	KAT6B KAT6A	6.96e-06	4	38	2	17980166
Pubmed	Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development.	CPHXL CPHXL2	1.16e-05	5	38	2	26360614
Pubmed	Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication.	KAT6B KAT6A	1.16e-05	5	38	2	17182677
Pubmed	Brpf1, a subunit of the MOZ histone acetyl transferase complex, maintains expression of anterior and posterior Hox genes for proper patterning of craniofacial and caudal skeletons.	HOXD10 KAT6A	1.16e-05	5	38	2	19254709
Pubmed	MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.	KAT6B KAT6A	1.16e-05	5	38	2	11965546
Pubmed	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.	KAT6B HDAC2 KAT6A	1.34e-05	42	38	3	16387653
Pubmed	Update of the human and mouse SERPIN gene superfamily.	SERPINE3 SERPINA6 SERPINA7	1.44e-05	43	38	3	24172014
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TRERF1 NCOA3 ARID1B RESF1 ADNP ARHGAP15 HDAC2 SCAF4	2.09e-05	1103	38	8	34189442
Pubmed	Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.	KAT6B KAT6A	2.43e-05	7	38	2	18794358
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	WWOX EIF4G3 KAT6B NFAT5 CERT1 MAML3 KAT6A MAD1L1 NAIP	2.50e-05	1489	38	9	28611215
Pubmed	WD repeat-containing mitotic checkpoint proteins act as transcriptional repressors during interphase.	HDAC2 MAD1L1	3.24e-05	8	38	2	15388328
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	NCOA3 RESF1 ADNP HDAC2	3.33e-05	167	38	4	20362541
Pubmed	New nomenclature for chromatin-modifying enzymes.	NCOA3 KAT6B KAT6A	3.38e-05	57	38	3	18022353
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	ARID1B KAT6B ADNP HDAC2 MAD1L1	3.39e-05	341	38	5	32971831
Pubmed	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	NCOA3 ARID1B	4.16e-05	9	38	2	19176441
Pubmed	TBR1 regulates autism risk genes in the developing neocortex.	ARID1B ADNP	4.16e-05	9	38	2	27325115
Pubmed	Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.	NCOA3 ARID1B	5.20e-05	10	38	2	16751102
Pubmed	Acetylation of HIV-1 integrase by p300 regulates viral integration.	KAT6B KAT6A	6.35e-05	11	38	2	16096645
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	TRERF1 ARID1B RESF1 ZIC2 CBX2	6.88e-05	396	38	5	26687479
Pubmed	The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions.	HOXD10 CBX2	9.00e-05	13	38	2	14973489
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	NCOA3 ARID1B ADNP HDAC2	9.71e-05	220	38	4	35785414
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOA3 ARID1B ADNP	1.04e-04	83	38	3	28794006
Pubmed	Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control.	ARID1B HDAC2	1.21e-04	15	38	2	17255939
Pubmed	Human transcription factor protein interaction networks.	TRERF1 NCOA3 ARID1B RESF1 ADNP HDAC2 SCAF4 CBX2	1.29e-04	1429	38	8	35140242
Pubmed	Functional genomics identifies a mechanism for estrogen activation of the retinoic acid receptor alpha1 gene in breast cancer cells.	NCOA3 HDAC2	1.38e-04	16	38	2	15831516
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ARID1B RESF1 KAT6B HDAC2 KAT6A ZIC2 ALG13	1.82e-04	1116	38	7	31753913
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TRERF1 NCOA3 CPHXL KAT6B NFAT5 CBX2	2.26e-04	808	38	6	20412781
Pubmed	Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.	NCOA3 ADNP HDAC2	2.59e-04	113	38	3	23403292
Pubmed	Global gene expression analysis of murine limb development.	KAT6B HOXD10 NFAT5	2.87e-04	117	38	3	22174793
Pubmed	cDNAs with long CAG trinucleotide repeats from human brain.	NCOA3 MAML3	2.90e-04	23	38	2	9225980
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	ARID1B RESF1 EIF4G3	3.33e-04	123	38	3	26912792
Pubmed	Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.	ADNP HDAC2 CBX2	3.41e-04	124	38	3	20850016
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	RESF1 ADNP HDAC2	3.49e-04	125	38	3	32891193
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	NCOA3 HOXD10 MAML3 POLR3A HDAC2 ZIC2	3.50e-04	877	38	6	20211142
Pubmed	EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.	ARID1B ADNP HDAC2	3.74e-04	128	38	3	23858473
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ADNP NFAT5 POLR3A HDAC2 ZIC2	4.13e-04	583	38	5	29844126
Pubmed	A census of human transcription factors: function, expression and evolution.	TRERF1 NCOA3 ADNP HOXD10 NFAT5 ZIC2	4.21e-04	908	38	6	19274049
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	ARID1B ADNP HDAC2	4.27e-04	134	38	3	25452129
Pubmed	REST repression of neuronal genes requires components of the hSWI.SNF complex.	ARID1B HDAC2	4.32e-04	28	38	2	12192000
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	CACNA1G KAT6B KAT6A MAD1L1 ALG13	5.00e-04	608	38	5	16713569
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZCCHC9 ADNP HDAC2 KAT6A CBX2	5.00e-04	608	38	5	36089195
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	ARID1B ADNP HDAC2 SCAF4	5.04e-04	339	38	4	30415952
Pubmed	PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5-WDR77/CRL4B complex to promote tumorigenesis.	NCOA3 HDAC2	5.30e-04	31	38	2	29846670
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ARID1B WWOX ADNP HDAC2 SCAF4 CBX2	5.47e-04	954	38	6	36373674
Pubmed	Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant.	HOXD10 ZIC2	5.65e-04	32	38	2	36737666
Pubmed	Characterization of molecules binding to the 70K N-terminal region of fibronectin by IFAST purification coupled with mass spectrometry.	SERPINA6 SERPINA7	5.65e-04	32	38	2	23750785
Pubmed	Interaction network of human early embryonic transcription factors.	TRERF1 NCOA3 ARID1B RESF1	5.74e-04	351	38	4	38297188
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRERF1 NCOA3 ADNP HDAC2 ZIC2 MAD1L1	5.74e-04	963	38	6	28671696
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	ARID1B ADNP HDAC2	5.94e-04	150	38	3	28242625
Pubmed	Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.	ARHGAP15 CERT1	6.38e-04	34	38	2	19197348
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	WWOX POLR3A SCAF4	6.41e-04	154	38	3	16055720
Pubmed	Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.	ADNP HDAC2	7.97e-04	38	38	2	33283408
Pubmed	Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.	ARID1B HDAC2	8.83e-04	40	38	2	34585037
Pubmed	The chromatin regulator Brpf1 regulates embryo development and cell proliferation.	KAT6B KAT6A	8.83e-04	40	38	2	25773539
Pubmed	PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes.	HDAC2 CBX2	9.28e-04	41	38	2	22325352
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	KAT6B HOXD10 NFAT5 MAML3 NAIP	9.98e-04	709	38	5	22988430
Pubmed	Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.	ARID1B ADNP	1.02e-03	43	38	2	36950384
Pubmed	A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.	CACNA1G NFAT5	1.07e-03	44	38	2	32492419
Interaction	QPRT interactions	ARID1B EIF4G3 ADNP SCAF4	1.18e-05	84	34	4	int:QPRT
Interaction	NANOG interactions	TRERF1 ARID1B RESF1 HDAC2 ZIC2 MAD1L1 CBX2	1.30e-05	481	34	7	int:NANOG
Interaction	BDH2 interactions	ZCCHC9 WWOX MAD1L1	4.15e-05	40	34	3	int:BDH2
Cytoband	Ensembl 112 genes in cytogenetic band chr16q23	CPHXL WWOX CPHXL2	1.24e-04	116	38	3	chr16q23
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	NCOA3 KAT6B KAT6A	2.76e-06	17	30	3	486
GeneFamily	Serpin peptidase inhibitors	SERPINE3 SERPINA6 SERPINA7	3.08e-05	37	30	3	739
GeneFamily	Zinc fingers C2HC-type\|PHD finger proteins\|Lysine acetyltransferases	KAT6B KAT6A	3.15e-04	16	30	2	66
GeneFamily	Ataxins\|Trinucleotide repeat containing	NCOA3 MAML3	7.80e-04	25	30	2	775
GeneFamily	PHD finger proteins	KAT6B KAT6A	9.74e-03	90	30	2	88
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ARID1B WWOX EIF4G3 ARHGAP15 NFAT5 MAML3	1.42e-08	193	38	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	NCOA3 ARID1B WWOX NFAT5 MAML3	5.14e-07	186	38	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	NCOA3 ARID1B WWOX NFAT5 MAML3	5.14e-07	186	38	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-3\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	ZCCHC9 WIPI1 CERT1 NAIP	1.11e-05	163	38	4	0e8d3c98209fc98b86b841d69051cee9e276d837
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	COLEC12 ARHGAP15 MAML3 NAIP	2.08e-05	191	38	4	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COLEC12 GBP2 SHISA2 ARHGAP15	2.08e-05	191	38	4	89d03c4133dda852a3713c0902a7d67941cf5b21
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	COLEC12 ARHGAP15 MAML3 NAIP	2.12e-05	192	38	4	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	BL\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GBP2 RESF1 ARHGAP15 NAIP	2.34e-05	197	38	4	1acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ARID1B WWOX EIF4G3 MAML3	2.44e-05	199	38	4	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 SHISA2 ARHGAP15	2.55e-04	145	38	3	051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 COLEC12 ARHGAP15	3.34e-04	159	38	3	323cb4a2416d2e6bff0a3f225d2edeae9ab7dc76
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SERPINE3 CERT1 MAML3	3.59e-04	163	38	3	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TRERF1 ARHGAP15 MAML3	3.72e-04	165	38	3	37615622c736e43260c38016e7c9e565ac97a3e8
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TRERF1 ARHGAP15 MAML3	3.72e-04	165	38	3	640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCell	nucseq-Immune-Hematopoietic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TRERF1 ARHGAP15 MAML3	3.72e-04	165	38	3	f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	ARID1B RESF1 MAML3	3.78e-04	166	38	3	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 RAD21L1 ARHGAP15	3.92e-04	168	38	3	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	Control-T_cells-Tregs\|Control / group, cell type (main and fine annotations)	GBP2 RESF1 ARHGAP15	3.99e-04	169	38	3	e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell	COVID-19-lung-MAST\|lung / Disease (COVID-19 only), tissue and cell type	TRERF1 ARHGAP15 MAML3	4.06e-04	170	38	3	e90f18e5462381b38e918442b38b1c8105291908
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RESF1 KAT6B ARHGAP15	4.13e-04	171	38	3	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SHISA2 KAT6B KAT6A	4.13e-04	171	38	3	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COLEC12 GBP2 ZIC2	4.34e-04	174	38	3	2891ab2fd05eb4bbd239d1a2865f21ef7f2df39e
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COLEC12 GBP2 ZIC2	4.34e-04	174	38	3	eade55f86ef1f7a5355ad65cec3aa6bfc5d3c62d
ToppCell	COVID-19-lung-MAST\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRERF1 ARHGAP15 MAML3	4.49e-04	176	38	3	473c45a381ca109207d66ed1635668b391ea0e1f
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	NCOA3 SHISA2 ADNP	4.64e-04	178	38	3	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADNP MAML3 POLR3A	4.64e-04	178	38	3	c87945146b2734141f07b39d268e0d8086ee0364
ToppCell	Adult-Immune-T_lymphocyte-D122\|Adult / Lineage, Cell type, age group and donor	TRERF1 RESF1 ARHGAP15	4.79e-04	180	38	3	06c371d0f0c5a7b234dd143e98800e19af95a8b5
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-Treg\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GBP2 RESF1 ARHGAP15	4.87e-04	181	38	3	a6c8b33a392de3df2f179317e329e45d3d8c6f52
ToppCell	RA-17._Lymphocyte\|RA / Chamber and Cluster_Paper	TRERF1 RESF1 ARHGAP15	4.95e-04	182	38	3	257a7847917b6ea1d60608183d90300bfd028758
ToppCell	LPS-IL1RA\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RESF1 EIF4G3 KAT6A	5.11e-04	184	38	3	c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	TRERF1 RESF1 ARHGAP15	5.19e-04	185	38	3	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NCOA3 WWOX NFAT5	5.19e-04	185	38	3	1d874608aa2062024323512f68889219471b2f00
ToppCell	Control-T_cells\|Control / group, cell type (main and fine annotations)	TRERF1 RESF1 ARHGAP15	5.36e-04	187	38	3	f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COLEC12 CACNA1G WIPI1	5.44e-04	188	38	3	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRERF1 RESF1 ARHGAP15	5.52e-04	189	38	3	df30478b288084a1bd48f660409dcc784040897c
ToppCell	Striatum-Endothelial\|Striatum / BrainAtlas - Mouse McCarroll V32	COLEC12 GBP2 ZIC2	5.52e-04	189	38	3	95ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ARID1B WWOX NFAT5	5.52e-04	189	38	3	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	COVID-19-T_cells-CD8+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	TRERF1 RESF1 ARHGAP15	5.52e-04	189	38	3	2c018d6120f65f0b2704b483bc9da1c0984872e3
ToppCell	COVID-19-Heart-Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COLEC12 ARHGAP15 NAIP	5.52e-04	189	38	3	2586f4088721c5debec86c2b211b739fd33713eb
ToppCell	Control-T_cells-CD4+_T_cells\|Control / group, cell type (main and fine annotations)	TRERF1 RESF1 ARHGAP15	5.61e-04	190	38	3	0733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 RESF1 ARHGAP15	5.61e-04	190	38	3	b772a5d281fe016f259ddda80d6f33d949dcac2b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 COLEC12 ARHGAP15	5.61e-04	190	38	3	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 COLEC12 ARHGAP15	5.61e-04	190	38	3	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 COLEC12 ARHGAP15	5.69e-04	191	38	3	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	COVID-19-lung-CD8+_T_cells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRERF1 RESF1 ARHGAP15	5.69e-04	191	38	3	543f8ae07cc2e6950c888115a5ca9445e3c0f618
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRERF1 RESF1 ARHGAP15	5.69e-04	191	38	3	c7be771543089fc94e5c62fd22f745189642aec3
ToppCell	Adult-Immune-T_lymphocyte-D175\|Adult / Lineage, Cell type, age group and donor	TRERF1 RESF1 ARHGAP15	5.69e-04	191	38	3	0b84fd1dc68146d9f72422b102744d2847f5ecb2
ToppCell	COVID-19-lung-CD4+_Treg\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRERF1 RESF1 ARHGAP15	5.69e-04	191	38	3	5a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCell	COVID-19-T_cells-CD4+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	TRERF1 RESF1 ARHGAP15	5.69e-04	191	38	3	0646cca78e24aeb6baa9934d3c439b797c567997
ToppCell	COVID-19-T_cells\|COVID-19 / group, cell type (main and fine annotations)	TRERF1 RESF1 ARHGAP15	5.69e-04	191	38	3	7f64add931b64b8d35836fa6bee9ebab593844d3
ToppCell	COVID-19-lung-CD4+_Treg\|lung / Disease (COVID-19 only), tissue and cell type	TRERF1 RESF1 ARHGAP15	5.69e-04	191	38	3	73ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP15 MAML3 NAIP	5.69e-04	191	38	3	47a2afc4102199b4bc76bd01b2967c8016186462
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1B WWOX NFAT5	5.78e-04	192	38	3	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	Hippocampus-Endothelial\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COLEC12 GBP2 ZIC2	5.78e-04	192	38	3	36deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	COLEC12 ARHGAP15 MAML3	5.78e-04	192	38	3	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	Adult-Immune-T_lymphocyte\|Adult / Lineage, Cell type, age group and donor	TRERF1 RESF1 ARHGAP15	5.87e-04	193	38	3	26df0c4c8a2355dd5503fadd07e368eb9a2bf06a
ToppCell	Children_(3_yrs)-Immune-monocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARHGAP15 MAML3 NAIP	5.87e-04	193	38	3	58e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell	RV-08._Macrophage\|RV / Chamber and Cluster_Paper	COLEC12 ARHGAP15 NAIP	5.87e-04	193	38	3	12bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1B WWOX NFAT5	5.87e-04	193	38	3	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	COVID-19-kidney-T-cells-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRERF1 RESF1 ARHGAP15	5.87e-04	193	38	3	5b84fa640cf30dea55fde53b810f850ff946d253
ToppCell	COVID-19-lung-CD4+_T_cells_metabolically_active\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRERF1 RESF1 ARHGAP15	5.87e-04	193	38	3	326fd2ce2c4b51e5a38f2a7a09f22f8f0e92735a
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRERF1 RESF1 ARHGAP15	5.87e-04	193	38	3	b9769b45125d2244afe53f9f71c92c04ddccf980
ToppCell	COVID-19-Heart-Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	COLEC12 ARHGAP15 NAIP	5.96e-04	194	38	3	f09675cd472200363c458952f00d2e41990800ee
ToppCell	COVID-19_Convalescent-PLT_4\|COVID-19_Convalescent / Disease Group and Platelet Clusters	NCOA3 WIPI1 RESF1	5.96e-04	194	38	3	ce1fad4e76a87f0c35e430ed1f2262395df882fd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COLEC12 ARHGAP15 NAIP	5.96e-04	194	38	3	1dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCell	Adult-Immune-T_lymphocyte-D231\|Adult / Lineage, Cell type, age group and donor	TRERF1 RESF1 ARHGAP15	5.96e-04	194	38	3	5c1dca33f382f37a7deb23e573578343c3b54986
ToppCell	LA-08._Macrophage\|World / Chamber and Cluster_Paper	COLEC12 ARHGAP15 NAIP	5.96e-04	194	38	3	c1805572bcc11b1cd29083329d7b5911489fb758
ToppCell	Immune-T_lymphocyte\|World / Lineage, Cell type, age group and donor	TRERF1 RESF1 ARHGAP15	5.96e-04	194	38	3	f47fa18c87b35a3960557f8169ff7830dd6ecb80
ToppCell	COVID-19-lung-CD4+_T_cells_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	TRERF1 RESF1 ARHGAP15	5.96e-04	194	38	3	2a144a1c2d537c8a59aa419206ddd96c23f0aeab
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TRERF1 COLEC12 SHISA2	6.05e-04	195	38	3	c5d2d9f12fd893331c9de261af30607d845d4f6a
ToppCell	mild-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PGBD1 NCOA3 KAT6B	6.05e-04	195	38	3	1e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCell	LA-08._Macrophage\|LA / Chamber and Cluster_Paper	COLEC12 ARHGAP15 NAIP	6.05e-04	195	38	3	5e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COLEC12 ARHGAP15 NAIP	6.05e-04	195	38	3	42bfdff88da1d07828c0ad65d412fb1752f0cee4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 COLEC12 ARHGAP15	6.05e-04	195	38	3	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	proximal-Hematologic-Natural_Killer_T-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRERF1 ARHGAP15 GSG1	6.05e-04	195	38	3	4d7c2c4d0130c2d46877ff6dd4584525d8f74daf
ToppCell	proximal-3-Hematologic-Natural_Killer_T\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRERF1 ARHGAP15 GSG1	6.05e-04	195	38	3	93093545bb23d2619ace029a52cffa1f673a0c2a
ToppCell	proximal-Hematologic-Natural_Killer_T\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRERF1 ARHGAP15 GSG1	6.05e-04	195	38	3	3944e4800f5d904d4efa401ce8913ec0e0781211
ToppCell	hematopoetic_progenitors-CD34+_MPP\|World / Lineage and Cell class	HDAC2 MAPKAPK3 CBX2	6.05e-04	195	38	3	851064ca1ab727b4972ad4b72234ee130998a799
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COLEC12 ARID1B RESF1	6.05e-04	195	38	3	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	Posterior_cortex-Endothelial\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COLEC12 GBP2 ZIC2	6.05e-04	195	38	3	988e3449691cc228cb55e5e30355136c97b12262
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COLEC12 ARHGAP15 NAIP	6.05e-04	195	38	3	34a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARHGAP15 MAML3 NAIP	6.14e-04	196	38	3	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	ARID1B WWOX MAML3	6.14e-04	196	38	3	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 COLEC12 ARHGAP15	6.23e-04	197	38	3	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COLEC12 ARHGAP15 MAML3	6.23e-04	197	38	3	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRERF1 ARHGAP15 MAML3	6.23e-04	197	38	3	bed8a9b73af5caee51b1232b31c24a59353658df
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Mast_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRERF1 ARHGAP15 MAML3	6.23e-04	197	38	3	b7d5073d44aa1e2cb83ea8d8104c5ed662665755
ToppCell	mLN-T_cell-Th1\|T_cell / Region, Cell class and subclass	COLEC12 SHISA2 GSG1	6.23e-04	197	38	3	5e39a49dddef04469ff2b615d755ddf6a926e58e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 COLEC12 ARHGAP15	6.23e-04	197	38	3	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1G ARHGAP15 HOXD10	6.23e-04	197	38	3	9af431323da6d099459b7360af40e5df998cffbd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP15 MAML3 NAIP	6.23e-04	197	38	3	1eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCell	distal-2-Hematologic-CD4+_Naive_T\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CACNA1G RESF1 ARHGAP15	6.23e-04	197	38	3	3339e9e03f5db6a0034d6424571b4f0b8983771b
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COLEC12 SHISA2 CACNA1G	6.23e-04	197	38	3	3fe665c0277d091290b63f0dd24c0c6536a45309
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 COLEC12 ARHGAP15	6.23e-04	197	38	3	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	distal-Hematologic-CD4+_Naive_T-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CACNA1G RESF1 ARHGAP15	6.32e-04	198	38	3	4db9eff17778ffc3f77c017ff64f55bc1626da24
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ARID1B WWOX MAML3	6.32e-04	198	38	3	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COLEC12 ARHGAP15 NAIP	6.32e-04	198	38	3	96883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCell	(1)_T_cell-(11)_Activated_CD4_T\|(1)_T_cell / shred on Cell_type and subtype	SHISA2 ARHGAP15 ALG13	6.32e-04	198	38	3	4b9ad91342f622c63e476d4f6a0ae5bf282a7ef5
ToppCell	mLN-T_cell-Th1\|mLN / Region, Cell class and subclass	COLEC12 SHISA2 GSG1	6.32e-04	198	38	3	7627b7c3a248da2bd5e1e6f7c226e5fd0bc92113
ToppCell	mLN-(1)_T_cell-(12)_Th1\|mLN / shred on region, Cell_type, and subtype	COLEC12 SHISA2 GSG1	6.32e-04	198	38	3	1fe8257233232b264b9ca630c2d92c509a195353
Drug	20-dihydrocortisone	WWOX SERPINA6	6.88e-06	3	35	2	CID000151132
Drug	anacardic acid	CACNA1G KAT6B KAT6A	1.31e-05	30	35	3	CID000167551
Drug	Ortho Evra	SERPINA6 SERPINA7	1.37e-05	4	35	2	ctd:C511292
Drug	2-methylbutyryl-CoA	WWOX KAT6B KAT6A	2.49e-05	37	35	3	CID000000054
Drug	AC1LCVO8	KAT6B KAT6A	6.39e-05	8	35	2	CID000656891
Drug	isovaleryl-CoA	WWOX KAT6B KAT6A	7.40e-05	53	35	3	CID000000810
Drug	3-Hydroxybutanoyl-Coenzyme A	WWOX KAT6B KAT6A	9.20e-05	57	35	3	CID000000521
Drug	benzoyl-S-CoA	WWOX KAT6B KAT6A	9.69e-05	58	35	3	CID000122174
Drug	AC1L2E0P	TRERF1 NCOA3 KAT6B HDAC2 KAT6A	1.01e-04	307	35	5	CID000019390
Drug	isoconazole	WWOX SERPINA6	1.03e-04	10	35	2	CID000003760
Drug	nanaomycin A	NCOA3 WWOX	1.03e-04	10	35	2	CID000040586
Drug	C04424	KAT6B KAT6A	1.25e-04	11	35	2	CID011953835
Drug	In-G	NCOA3 KAT6B HDAC2 KAT6A	1.31e-04	170	35	4	CID000446054
Drug	AC1L1A2K	WWOX KAT6B KAT6A	1.42e-04	66	35	3	CID000000808
Drug	C05118	KAT6B KAT6A	1.50e-04	12	35	2	CID000440565
Drug	C05119	KAT6B KAT6A	1.50e-04	12	35	2	CID000440566
Drug	thioridazine hydrochloride; Up 200; 10uM; HL60; HT_HG-U133A	NCOA3 GBP2 WIPI1 KAT6B	1.63e-04	180	35	4	1171_UP
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; PC3; HT_HG-U133A	NCOA3 EIF4G3 KAT6B MAD1L1	1.67e-04	181	35	4	1791_DN
Drug	AC1L9EUB	KAT6B KAT6A	1.77e-04	13	35	2	CID000443527
Drug	4-formyl-benzoate	WWOX KAT6B	1.77e-04	13	35	2	CID000012088
Drug	Sulfaphenazole [526-08-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A	GBP2 KAT6B NFAT5 CERT1	1.81e-04	185	35	4	1673_DN
Drug	Corynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A	KAT6B NFAT5 SCAF4 KAT6A	2.05e-04	191	35	4	4811_DN
Drug	AC1L9EU8	KAT6B KAT6A	2.07e-04	14	35	2	CID000443526
Drug	AC1LCVO5	KAT6B KAT6A	2.07e-04	14	35	2	CID000656890
Drug	Mefloquine hydrochloride [51773-92-3]; Up 200; 9.6uM; HL60; HG-U133A	GBP2 NFAT5 CERT1 SCAF4	2.18e-04	194	35	4	1364_UP
Drug	Pentamidine isethionate [140-64-7]; Down 200; 6.8uM; MCF7; HT_HG-U133A	GBP2 WWOX SCAF4 KAT6A	2.22e-04	195	35	4	4396_DN
Drug	SC 19220; Up 200; 10uM; MCF7; HT_HG-U133A	GBP2 WWOX KAT6B NFAT5	2.22e-04	195	35	4	7060_UP
Drug	Ketoconazole [65277-42-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A	GBP2 EIF4G3 NFAT5 KAT6A	2.31e-04	197	35	4	5685_DN
Drug	Amiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; HL60; HG-U133A	NCOA3 GBP2 NFAT5 ALG13	2.35e-04	198	35	4	1970_DN
Drug	Cefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; PC3; HT_HG-U133A	NCOA3 RESF1 CERT1 SCAF4	2.40e-04	199	35	4	7148_DN
Drug	Acenocoumarol [152-72-7]; Down 200; 11.4uM; PC3; HT_HG-U133A	NCOA3 RESF1 NFAT5 SCAF4	2.40e-04	199	35	4	2077_DN
Drug	Isopyrin hydrochloride [18342-39-7]; Down 200; 14.2uM; PC3; HT_HG-U133A	NCOA3 WIPI1 RESF1 KAT6A	2.40e-04	199	35	4	5879_DN
Drug	Diazoxide [364-98-7]; Up 200; 17.4uM; HL60; HG-U133A	EIF4G3 NFAT5 CERT1 ALG13	2.44e-04	200	35	4	1368_UP
Drug	Artemisinin [63968-64-9]; Up 200; 14.2uM; HL60; HG-U133A	NCOA3 KAT6B NFAT5 SCAF4	2.44e-04	200	35	4	1714_UP
Disease	Neurodevelopmental Disorders	ARID1B ADNP CERT1 ALG13	5.04e-06	93	36	4	C1535926
Disease	Epilepsy, Cryptogenic	ARID1B CERT1 ALG13	1.38e-04	82	36	3	C0086237
Disease	Awakening Epilepsy	ARID1B CERT1 ALG13	1.38e-04	82	36	3	C0751111
Disease	Aura	ARID1B CERT1 ALG13	1.38e-04	82	36	3	C0236018
Disease	ischemia (implicated_via_orthology)	ARID1B ADNP	1.95e-04	17	36	2	DOID:326 (implicated_via_orthology)
Disease	neuroticism measurement, wellbeing measurement, depressive symptom measurement	EIF4G3 MAML3	2.44e-04	19	36	2	EFO_0007006, EFO_0007660, EFO_0007869
Disease	Adenocarcinoma of prostate	HDAC2 MAD1L1	2.71e-04	20	36	2	C0007112
Disease	risk-taking behaviour	CACNA1G ARID1B EIF4G3 NFAT5 SCAF4 MAD1L1	2.97e-04	764	36	6	EFO_0008579
Disease	Epilepsy	ARID1B CERT1 ALG13	3.20e-04	109	36	3	C0014544
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	ARID1B ARHGAP15 NFAT5 MAML3 SCAF4 MAD1L1	3.82e-04	801	36	6	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	peptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease	MAML3 MAD1L1	3.93e-04	24	36	2	EFO_0003948, EFO_0009923, MONDO_0004247
Disease	Squamous cell carcinoma	NCOA3 WWOX HDAC2	4.67e-04	124	36	3	C0007137
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	WWOX KAT6B MAD1L1	5.49e-04	131	36	3	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	WWOX KAT6B MAD1L1	5.49e-04	131	36	3	C4552091
Disease	Juvenile arthritis	WWOX KAT6B MAD1L1	5.49e-04	131	36	3	C3495559
Disease	Juvenile psoriatic arthritis	WWOX KAT6B MAD1L1	5.49e-04	131	36	3	C3714758
Disease	C-reactive protein measurement	TRERF1 WWOX EIF4G3 SERPINA6 NFAT5 MAML3 SCAF4	5.52e-04	1206	36	7	EFO_0004458
Disease	Juvenile-Onset Still Disease	WWOX KAT6B MAD1L1	5.99e-04	135	36	3	C0087031
Disease	Spinocerebellar Ataxia Type 2	CACNA1G WWOX	7.92e-04	34	36	2	C0752121
Disease	Spinocerebellar Ataxia Type 1	CACNA1G WWOX	7.92e-04	34	36	2	C0752120
Disease	Spinocerebellar Ataxia Type 5	CACNA1G WWOX	7.92e-04	34	36	2	C0752123
Disease	Spinocerebellar Ataxia Type 7	CACNA1G WWOX	7.92e-04	34	36	2	C0752125
Disease	Spinocerebellar Ataxia Type 6 (disorder)	CACNA1G WWOX	7.92e-04	34	36	2	C0752124
Disease	Ataxia, Spinocerebellar	CACNA1G WWOX	7.92e-04	34	36	2	C0087012
Disease	Spinocerebellar Ataxia Type 4	CACNA1G WWOX	8.40e-04	35	36	2	C0752122
Disease	age at first sexual intercourse measurement	WWOX ARHGAP15 MAML3 MAD1L1	1.19e-03	383	36	4	EFO_0009749

Protein segments in the cluster

Peptide	Gene	Start	Entry
KQINSPMMTVSAYNN	NAIP	776	Q13075
MMSSVHLQQNNYGVK	ADNP	321	Q9H2P0
MVYVPQMQQQLHVEN	ALG13	1001	Q9NP73
HMMYSQVFQATVNLG	GSG1	206	Q2KHT4
GVTMAQYQQSQHNLM	ARID1B	2236	Q8NFD5
QYQQSQHNLMHMQPP	ARID1B	2241	Q8NFD5
QNIVETSMMQEPNYQ	RAD21L1	391	Q9H4I0
QKYNVSCIMIMPQHQ	KAT6B	851	Q8WYB5
QVEEMVQNHMTYSLQ	CERT1	396	Q9Y5P4
SAPGSLQMQYQQSMQ	MAD1L1	36	Q9Y6D9
TQFMNHPWINQSMVV	MAPKAPK3	296	Q16644
LQKTTMNNYLPQNHM	MAML3	561	Q96JK9
HYNQTTSPLYNMTNM	LIPJ	286	Q5W064
NLQNQMYSHNVVIMN	COLEC12	191	Q5KU26
MGTINQQAMDQLHYV	GBP2	131	P32456
LQQSPVYQQTSHMMS	NFAT5	926	O94916
VNLMPTPAYNVNSMN	KAT6A	1901	Q92794
TPAYNVNSMNMNTLN	KAT6A	1906	Q92794
IVHYMNRMTQSQAQA	CBX2	256	Q14781
IGLNVVTMAMEHYQQ	CACNA1G	1621	O43497
QHQQPQNYSEGMMLQ	CPHXL2	291	A0A1W2PPK0
EVNHQNMGMNVHPYI	HOXD10	61	P28358
ISPSNMTNQNTPEYM	HDAC2	346	Q92769
GMQQPAYTQHQNMDQ	SCAF4	326	O95104
AYTQHQNMDQFQPRM	SCAF4	331	O95104
QTPTAVYQANQHIMM	EIF4G3	36	O43432
VYQANQHIMMVNHLP	EIF4G3	41	O43432
QAMDPNAAYVNMSNH	SERPINA6	21	P08185
QQHQQPQNYLEGMML	CPHXL	316	A0A1W2PPM1
NPSQQTALSMVMHNY	RESF1	731	Q9HCM1
PMMQHPQAASIYQSS	NCOA3	1346	Q9Y6Q9
GNMAIHMVYQNQIAE	ARHGAP15	446	Q53QZ3
TIINEIQYTMVNHGM	POLR3A	1266	O14802
GTMNNVYVNMPTNFS	SHISA2	211	Q6UWI4
QQASVYIQGQDMHPM	PGBD1	131	Q96JS3
TTVQVPMMHQMEQYY	SERPINA7	231	P05543
VTSNAVHPGNMMYSN	WWOX	316	Q9NZC7
QVPMMHQTTEVNYGQ	SERPINE3	221	A8MV23
MEYLRQNSQMVHNGQ	ZCCHC9	76	Q8N567
FIQMSQNQPYHRSMQ	ZBED9	501	Q6R2W3
ATNYLPTQVSDMMHQ	WIPI1	286	Q5MNZ9
SAAQLHNQYGPMNMN	ZIC2	206	O95409
YYQPQPMMQHLQEQQ	TRERF1	326	Q96PN7