Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GABA receptor binding	AKAP5 PLCL2 PLCL1	7.24e-05	20	82	3	GO:0050811
Domain	PH_12	PLCL2 PLCL1	2.76e-04	6	81	2	PF16457
Domain	-	EFCAB6 PLCL2 MACF1 ACTN4 PLCL1 RYR2	9.51e-04	261	81	6	1.10.238.10
Domain	EF-hand-dom_pair	EFCAB6 PLCL2 MACF1 ACTN4 PLCL1 RYR2	1.55e-03	287	81	6	IPR011992
Domain	PLipase_C_Pinositol-sp_Y	PLCL2 PLCL1	1.88e-03	15	81	2	IPR001711
Domain	EF-hand_like	PLCL2 PLCL1	1.88e-03	15	81	2	PF09279
Domain	Myosin_N	MYH7 MYH10	1.88e-03	15	81	2	PF02736
Domain	PIPLC_Y_DOMAIN	PLCL2 PLCL1	1.88e-03	15	81	2	PS50008
Domain	Myosin_N	MYH7 MYH10	1.88e-03	15	81	2	IPR004009
Domain	PI-PLC_fam	PLCL2 PLCL1	1.88e-03	15	81	2	IPR001192
Domain	PLC_EF-hand-like	PLCL2 PLCL1	1.88e-03	15	81	2	IPR015359
Domain	PI-PLC-Y	PLCL2 PLCL1	1.88e-03	15	81	2	PF00387
Domain	PLCYc	PLCL2 PLCL1	1.88e-03	15	81	2	SM00149
Domain	Actin_CS	POTEF POTEI	2.14e-03	16	81	2	IPR004001
Domain	ACTINS_2	POTEF POTEI	2.42e-03	17	81	2	PS00432
Domain	Myosin_tail_1	MYH7 MYH10	2.72e-03	18	81	2	PF01576
Domain	Myosin_tail	MYH7 MYH10	2.72e-03	18	81	2	IPR002928
Domain	PI-PLC-X	PLCL2 PLCL1	2.72e-03	18	81	2	PF00388
Domain	Actin/actin-like_CS	POTEF POTEI	2.72e-03	18	81	2	IPR020902
Domain	PLCXc	PLCL2 PLCL1	2.72e-03	18	81	2	SM00148
Domain	PIPLC_X_DOMAIN	PLCL2 PLCL1	3.03e-03	19	81	2	PS50007
Domain	PLipase_C_PInositol-sp_X_dom	PLCL2 PLCL1	3.03e-03	19	81	2	IPR000909
Domain	Myosin-like_IQ_dom	MYH7 MYH10	3.03e-03	19	81	2	IPR027401
Domain	-	MYH7 MYH10	3.03e-03	19	81	2	4.10.270.10
Domain	ACTINS_ACT_LIKE	POTEF POTEI	3.03e-03	19	81	2	PS01132
Domain	Actinin_actin-bd_CS	MACF1 ACTN4	4.43e-03	23	81	2	IPR001589
Domain	Spectrin	MACF1 ACTN4	4.43e-03	23	81	2	PF00435
Domain	ACTININ_2	MACF1 ACTN4	4.43e-03	23	81	2	PS00020
Domain	ACTININ_1	MACF1 ACTN4	4.43e-03	23	81	2	PS00019
Domain	ANK	POTEB3 POTEF POTED POTEI POTEC	4.71e-03	251	81	5	SM00248
Domain	ANK_REPEAT	POTEB3 POTEF POTED POTEI POTEC	4.87e-03	253	81	5	PS50088
Domain	ANK_REP_REGION	POTEB3 POTEF POTED POTEI POTEC	4.95e-03	254	81	5	PS50297
Domain	EFh	EFCAB6 MACF1 ACTN4 RYR2	4.95e-03	158	81	4	SM00054
Domain	-	PLCL2 PLCL1	5.22e-03	25	81	2	3.20.20.190
Domain	PLC-like_Pdiesterase_TIM-brl	PLCL2 PLCL1	5.22e-03	25	81	2	IPR017946
Domain	IQ	MYH7 MYH10 CEP97	5.26e-03	81	81	3	SM00015
Domain	Ankyrin_rpt	POTEB3 POTEF POTED POTEI POTEC	5.63e-03	262	81	5	IPR002110
Domain	Spectrin_repeat	MACF1 ACTN4	6.99e-03	29	81	2	IPR002017
Domain	IQ_motif_EF-hand-BS	MYH7 MYH10 CEP97	7.04e-03	90	81	3	IPR000048
Domain	IQ	MYH7 MYH10 CEP97	7.71e-03	93	81	3	PS50096
Domain	Actin	POTEF POTEI	7.96e-03	31	81	2	IPR004000
Domain	Actin	POTEF POTEI	7.96e-03	31	81	2	PF00022
Domain	ACTIN	POTEF POTEI	7.96e-03	31	81	2	SM00268
Domain	Spectrin/alpha-actinin	MACF1 ACTN4	8.47e-03	32	81	2	IPR018159
Domain	PAS	NCOA1 PASD1	8.47e-03	32	81	2	SM00091
Domain	SPEC	MACF1 ACTN4	8.47e-03	32	81	2	SM00150
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TUBGCP6 AKAP5 ILF3 PSIP1 CENPC MACO1 KTN1 VPS35 OTUB1 PDCD11 MRPL19 MACF1 SLC30A1 OGA TRIM24 PREPL GOLGA3	6.82e-08	1487	83	17	33957083
Pubmed	Functional proteomics mapping of a human signaling pathway.	MYH10 RNF168 ZNF484 EXPH5 MACO1 VPS35 OTUB1 PLCL2 MACF1 MGA RYR2	1.66e-07	591	83	11	15231748
Pubmed	POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.	POTEB3 POTED POTEC	7.28e-07	8	83	3	12475935
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CUL1 KDM3A USP6 MYH10 CTPS2 CELF1 PRIM1 KTN1 VPS35 OTUB1 OGA PREPL ARMC8	7.39e-07	1005	83	13	19615732
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	MYH10 ILF3 ACACA KTN1 VPS35 OTUB1 PDCD11 ACTN4 SLC30A1	2.40e-06	484	83	9	31995728
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	MYH10 ILF3 KTN1 VPS35 ACTN4 TRIM24	4.64e-06	179	83	6	36261009
Pubmed	Gene dosage affects the cardiac and brain phenotype in nonmuscle myosin II-B-depleted mice.	MYH7 MYH10	5.63e-06	2	83	2	10712438
Pubmed	Phospholipase C-related but catalytically inactive protein acts as a positive regulator of insulin signalling in adipocytes.	PLCL2 PLCL1	5.63e-06	2	83	2	34859819
Pubmed	Phospholipase C-related catalytically inactive protein regulates lipopolysaccharide-induced hypothalamic inflammation-mediated anorexia in mice.	PLCL2 PLCL1	5.63e-06	2	83	2	31589911
Pubmed	Phospholipase C-related inactive protein is involved in trafficking of gamma2 subunit-containing GABA(A) receptors to the cell surface.	PLCL2 PLCL1	5.63e-06	2	83	2	17301177
Pubmed	Inflammatory corpuscle AIM2 facilitates macrophage foam cell formation by inhibiting cholesterol efflux protein ABCA1.	ABCA1 AIM2	5.63e-06	2	83	2	38734775
Pubmed	Involvement of phospholipase C-related inactive protein in the mouse reproductive system through the regulation of gonadotropin levels.	PLCL2 PLCL1	5.63e-06	2	83	2	19553601
Pubmed	Genetic reduction of GABA(A) receptor gamma2 subunit expression potentiates the immobilizing action of isoflurane.	PLCL2 PLCL1	5.63e-06	2	83	2	20097266
Pubmed	Phospholipase C-related inactive protein is implicated in the constitutive internalization of GABAA receptors mediated by clathrin and AP2 adaptor complex.	PLCL2 PLCL1	5.63e-06	2	83	2	17254016
Pubmed	Phospholipase C-related but catalytically inactive protein is required for insulin-induced cell surface expression of gamma-aminobutyric acid type A receptors.	PLCL2 PLCL1	5.63e-06	2	83	2	19996098
Pubmed	Identification and characterization of a new phospholipase C-like protein, PLC-L(2).	PLCL2 PLCL1	5.63e-06	2	83	2	10581172
Pubmed	Transactivation of involucrin, a marker of differentiation in keratinocytes, by lens epithelium-derived growth factor (LEDGF).	IVL PSIP1	5.63e-06	2	83	2	12126624
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	ACACA MYPN MACF1 ACTN4 CEP97 GOLGA3	1.13e-05	209	83	6	36779422
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	MYH7 CTPS2 VPS35 OTUB1 MACF1 SLC30A1 TRIM24	1.24e-05	322	83	7	26514267
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	SETDB2 MYOF MYH7 ACACA TMOD1 OGA TRIM24 MGA GOLGA3 MAP3K19	1.26e-05	754	83	10	35906200
Pubmed	Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres.	CENPC CENPH	1.69e-05	3	83	2	17651496
Pubmed	Phospholipase C-related but catalytically inactive protein modulates pain behavior in a neuropathic pain model in mice.	PLCL2 PLCL1	1.69e-05	3	83	2	23639135
Pubmed	Phospholipase C-related catalytically inactive protein, a novel microtubule-associated protein 1 light chain 3-binding protein, negatively regulates autophagosome formation.	PLCL2 PLCL1	1.69e-05	3	83	2	23399561
Pubmed	Phospholipase C-related catalytically inactive protein (PRIP) regulates lipolysis in adipose tissue by modulating the phosphorylation of hormone-sensitive lipase.	PLCL2 PLCL1	1.69e-05	3	83	2	24945349
Pubmed	Phospholipase C-related Catalytically Inactive Protein Is a New Modulator of Thermogenesis Promoted by β-Adrenergic Receptors in Brown Adipocytes.	PLCL2 PLCL1	1.69e-05	3	83	2	26706316
Pubmed	Involvement of PRIP, phospholipase C-related, but catalytically inactive protein, in bone formation.	PLCL2 PLCL1	1.69e-05	3	83	2	21757756
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	KDM3A GSE1 CENPC PDCD11 OGA TRIM24 MGA	1.73e-05	339	83	7	30415952
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	NES MYH7 MYH10 ILF3 ACACA VPS35 OTUB1 MACF1 ACTN4 XRCC4 OGA PREPL	1.78e-05	1149	83	12	35446349
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CUL1 NES MYH10 ILF3 ACACA CENPC KTN1 VPS35 PDCD11 MACF1 ACTN4 PRR14L MGA	1.85e-05	1353	83	13	29467282
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MYOF EXPH5 KTN1 TTC21B MACF1 MINAR1 MGA PDZRN4	2.40e-05	493	83	8	15368895
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	MYH7 GSE1 KTN1 MYPN MACF1 ACTN4 MGA PREPL	2.54e-05	497	83	8	23414517
Pubmed	Identification of pathogenic variants in genes related to channelopathy and cardiomyopathy in Korean sudden cardiac arrest survivors.	MYH7 RYR2	3.37e-05	4	83	2	28202948
Pubmed	Phospholipase C-related, but catalytically inactive protein (PRIP) up-regulates osteoclast differentiation via calcium-calcineurin-NFATc1 signaling.	PLCL2 PLCL1	3.37e-05	4	83	2	28341745
Pubmed	Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor.	NCOA1 TRIM24	3.37e-05	4	83	2	10935545
Pubmed	Changes in expression of nonmuscle myosin heavy chain isoforms during muscle and nonmuscle tissue development.	MYH7 MYH10	3.37e-05	4	83	2	8482409
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYH7 MYH10 AKAP5 ILF3 PSIP1 CENPC POTEF KTN1 VPS35 MACF1 ACTN4 POTEI RYR2	3.59e-05	1442	83	13	35575683
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	CUL1 MYH7 MYH10 POTEF PRIM1 KTN1 MACF1 ACTN4	4.44e-05	538	83	8	28524877
Pubmed	Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.	ABCA1 NCOA1	5.60e-05	5	83	2	14993927
Pubmed	Multiscale analysis of single and double maternal-zygotic Myh9 and Myh10 mutants during mouse preimplantation development.	MYH7 MYH10	5.60e-05	5	83	2	33871354
Pubmed	A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis.	NES XRCC4	5.60e-05	5	83	2	9875844
Pubmed	ASD-Associated De Novo Mutations in Five Actin Regulators Show Both Shared and Distinct Defects in Dendritic Spines and Inhibitory Synapses in Cultured Hippocampal Neurons.	MYH10 ACTN4	5.60e-05	5	83	2	30123108
Pubmed	Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1.	RNF168 OTUB1	5.60e-05	5	83	2	20725033
Pubmed	Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.	MYH7 TMOD1 RYR2	7.43e-05	34	83	3	31024170
Pubmed	Hypertrophic Cardiomyopathy Overview	MYH7 MYPN RYR2	7.43e-05	34	83	3	20301725
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	MYOF MYH10 ILF3 KTN1 VPS35	7.75e-05	182	83	5	31067453
Pubmed	GABA(A) receptor subunit alteration-dependent diazepam insensitivity in the cerebellum of phospholipase C-related inactive protein knockout mice.	PLCL2 PLCL1	8.39e-05	6	83	2	20412381
Pubmed	Activation of ATP-binding cassette transporter A1 transcription by chromatin remodeling complex.	ABCA1 NCOA1	8.39e-05	6	83	2	15774904
Pubmed	Mechanistic aspects of estrogen receptor activation probed with constitutively active estrogen receptors: correlations with DNA and coregulator interactions and receptor conformational changes.	NCOA1 TRIM24	8.39e-05	6	83	2	9259327
Pubmed	TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT-GSK-3β-β-Catenin Signaling Pathway.	MYOF MYH7 MYH10 ILF3 ACTN4 POTEI	9.28e-05	305	83	6	33194618
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	KDM3A ILF3 ACACA CELF1 TRIM24 MGA CEP97	9.50e-05	444	83	7	34795231
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NES MYH10 ILF3 KTN1 MACF1 PLCL1 MGA PREPL GOLGA3 ARMC8	9.89e-05	963	83	10	28671696
Pubmed	Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths.	POTEB3 POTED	1.17e-04	7	83	2	15276201
Pubmed	Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.	MYH7 MYH10	1.17e-04	7	83	2	21126233
Pubmed	Retroviral DNA integration--mechanism and consequences.	PSIP1 XRCC4	1.17e-04	7	83	2	16291214
Pubmed	Modulation of GABA(A) receptor phosphorylation and membrane trafficking by phospholipase C-related inactive protein/protein phosphatase 1 and 2A signaling complex underlying brain-derived neurotrophic factor-dependent regulation of GABAergic inhibition.	PLCL2 PLCL1	1.17e-04	7	83	2	16754670
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	MYH10 ILF3 POTEF PDCD11 GOLGA3	1.26e-04	202	83	5	24639526
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	CUL1 MYOF MYH10 ILF3 ACACA PSIP1 KTN1 MACF1 ACTN4	1.32e-04	807	83	9	30575818
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CUL1 MYH10 ILF3 ACACA PSIP1 PRIM1 KTN1 VPS35 OTUB1 PDCD11 ACTN4 ARMC8	1.40e-04	1425	83	12	30948266
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	USP6 MXRA5 GSE1 KTN1 NCOA1 TRIM24 PREPL RYR2	1.45e-04	638	83	8	31182584
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	CUL1 ILF3 RNF168 PSIP1 CENPC CENPH PRIM1 OTUB1 POLR2K XRCC4	1.51e-04	1014	83	10	32416067
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	EVI5 CUL1 MYOF MYH10 PSIP1 MACO1 KTN1 VPS35 OTUB1 TMOD1 PDCD11 ARMC8	1.55e-04	1440	83	12	30833792
Pubmed	Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.	IVL ABCA1	1.56e-04	8	83	2	24293640
Pubmed	Different classes of coactivators recognize distinct but overlapping binding sites on the estrogen receptor ligand binding domain.	NCOA1 TRIM24	1.56e-04	8	83	2	9774463
Pubmed	Phospholipase C-related but catalytically inactive proteins regulate ovarian follicle development.	PLCL2 PLCL1	1.56e-04	8	83	2	28360101
Pubmed	A human MAP kinase interactome.	MYH10 KIAA1549L EXPH5 KTN1 MACF1 ACTN4 MGA	1.66e-04	486	83	7	20936779
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	CUL1 MYOF MYH10 ILF3 PSIP1 CELF1	1.67e-04	340	83	6	24332808
Pubmed	Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.	KDM3A ILF3 PDCD11 OGA	1.76e-04	116	83	4	21282530
Pubmed	Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality.	MYH7 TMOD1	2.00e-04	9	83	2	26487682
Pubmed	MACF1 regulates the migration of pyramidal neurons via microtubule dynamics and GSK-3 signaling.	NES MACF1	2.00e-04	9	83	2	25224226
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTED POTEI	2.00e-04	9	83	2	16364570
Pubmed	FBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1.	CUL1 PRIM1	2.00e-04	9	83	2	32576198
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	CUL1 MYH7 MYH10 GSE1 PSIP1 KTN1 TRIM24 MGA ARMC8	2.07e-04	857	83	9	25609649
Pubmed	Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0.	MYH10 ILF3 VPS35 ACTN4	2.28e-04	124	83	4	35516420
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	ZNF484 MACO1 NCOA1 MAGEE1 SLC30A1	2.45e-04	233	83	5	37704626
Pubmed	Comparative mapping in the beige-satin region of mouse chromosome 13.	INHBA RYR2	2.50e-04	10	83	2	9027500
Pubmed	Natural helix 9 mutants of PPARγ differently affect its transcriptional activity.	NCOA1 TRIM24	2.50e-04	10	83	2	30595551
Pubmed	Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.	TMOD1 ACTN4	2.50e-04	10	83	2	20368620
Pubmed	Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.	CENPC CENPH	2.50e-04	10	83	2	16716197
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	ILF3 KIAA1549L PSIP1 VPS35 MACF1	2.50e-04	234	83	5	36243803
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	MYOF POTEF MACF1 ACTN4 OGA	2.55e-04	235	83	5	28378594
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	CUL1 KDM3A ILF3 GSE1 PSIP1 CELF1 OTUB1 NCOA1 ACTN4 TRIM24	2.95e-04	1103	83	10	34189442
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	IVL CENPH KTN1 OTUB1 PLCL2 TTC21B ACTN4 XRCC4 CEP97 CCDC144A ARMC8	3.00e-04	1321	83	11	27173435
Pubmed	The Tlx gene regulates the timing of neurogenesis in the cortex.	NES SALL3	3.05e-04	11	83	2	15385616
Pubmed	FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4.	CUL1 XRCC4	3.05e-04	11	83	2	26774286
Pubmed	Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development.	NES CELF1	3.05e-04	11	83	2	32245946
Pubmed	New nomenclature for chromatin-modifying enzymes.	KDM3A SETDB2 NCOA1	3.49e-04	57	83	3	18022353
Pubmed	NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function.	MYH7 RYR2	3.66e-04	12	83	2	14633990
Pubmed	Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.	MYH7 MYH10	3.66e-04	12	83	2	8424456
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	MYH10 ILF3 ACACA GSE1 PSIP1 KTN1 MACF1 PRR14L OGA	3.89e-04	934	83	9	33916271
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	MYOF ILF3 OTUB1 PDCD11	4.02e-04	144	83	4	35681168
Pubmed	A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.	CELF1 KTN1 ACTN4	4.07e-04	60	83	3	19075228
Pubmed	Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase.	ABCA1 ILF3 PDZRN4	4.07e-04	60	83	3	22889411
Pubmed	A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.	MYH7 MYH10 RNF168	4.07e-04	60	83	3	20682791
Pubmed	Biological, clinical and population relevance of 95 loci for blood lipids.	EVI5 ABCA1 MACO1 MACF1	4.23e-04	146	83	4	20686565
Pubmed	CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.	MYOF OTUB1 MRPL19	4.92e-04	64	83	3	36369321
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	CUL1 MYH7 ACACA MACF1	4.93e-04	152	83	4	34299191
Pubmed	Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha.	NCOA1 PLCL1	5.03e-04	14	83	2	12039952
Pubmed	Multiplexed molecular interactions of nuclear receptors using fluorescent microspheres.	NCOA1 TRIM24	5.03e-04	14	83	2	11500849
Pubmed	The Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress Granules.	ILF3 VPS35 ACTN4	5.14e-04	65	83	3	32521226
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	AKAP5 CTPS2 ACACA MACF1 SLC30A1 GOLGA3	5.23e-04	421	83	6	36976175
Interaction	POTEC interactions	POTEB3 POTEF POTED POTEC	1.86e-07	13	83	4	int:POTEC
Interaction	POTED interactions	POTEB3 POTED POTEC	2.69e-07	4	83	3	int:POTED
Interaction	POTEB3 interactions	POTEB3 POTEF MACO1 POTED POTEC	3.09e-07	35	83	5	int:POTEB3
Interaction	NPM1 interactions	CUL1 MYH7 MYH10 AKAP5 ILF3 ACACA PSIP1 CENPC KTN1 OTUB1 PDCD11 MRPL19 XRCC4 TRIM24 AIM2 GOLGA3 NPM2	6.49e-06	1201	83	17	int:NPM1
Interaction	TRIM52 interactions	MEIOC EXPH5 PRR14L TRIM24 MGA CEP97	1.84e-05	133	83	6	int:TRIM52
Interaction	GOLGA4 interactions	MYH10 ACACA VPS35 TMOD1 MACF1 GOLGA3 DIRAS3	4.10e-05	226	83	7	int:GOLGA4
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEF POTED POTEI POTEC	4.27e-08	13	52	4	685
GeneFamily	Ankyrin repeat domain containing	POTEF POTED POTEI POTEC ANKRD18B	6.42e-04	242	52	5	403
GeneFamily	Myosin heavy chains	MYH7 MYH10	8.32e-04	15	52	2	1098
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCL2 PLCL1	1.34e-03	19	52	2	832
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYOF ABCA1 MYH10 MXRA5 MACF1 RYR2	1.86e-06	197	83	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH10 KIAA1549L CENPH PRIM1 MACF1	1.66e-05	170	83	5	e20568c8f3f17d94de78229617eb2f7e4c5af2bc
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NES INHBA PLCL1 RYR2 PDZRN4	1.71e-05	171	83	5	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH10 KIAA1549L CENPH PRIM1 MACF1	1.96e-05	176	83	5	d30241fb8119834d6e7b59efec3f92fc7a3d1247
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CUL1 MYH10 MEIOC PRIM1 MACF1	1.96e-05	176	83	5	cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACACA MEIOC MACF1 MGA CEP97	2.07e-05	178	83	5	c87945146b2734141f07b39d268e0d8086ee0364
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NES MYH10 PSIP1 CENPH PRIM1	2.13e-05	179	83	5	ff678e2f33c914e3dd0f338ada25f506c3e3c980
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH7 MYPN TMOD1 PLCL1 RYR2	2.25e-05	181	83	5	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	MYOF MYH10 MACF1 RYR2 PDZRN4	2.69e-05	188	83	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN TMOD1 RYR2 PDZRN4	2.76e-05	189	83	5	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN TMOD1 RYR2 PDZRN4	2.76e-05	189	83	5	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	MYH7 MYPN ACTN4 PLCL1 RYR2	2.76e-05	189	83	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 BEND6 TMOD1 RYR2 PDZRN4	2.83e-05	190	83	5	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	MYH7 MYPN ACTN4 PLCL1 RYR2	2.83e-05	190	83	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 BEND6 TMOD1 RYR2 PDZRN4	2.83e-05	190	83	5	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	MYH7 MYPN PLCL2 PLCL1 RYR2	2.90e-05	191	83	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN TMOD1 RYR2 PDZRN4	2.90e-05	191	83	5	c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN TMOD1 RYR2 PDZRN4	2.90e-05	191	83	5	715f5b449b8e075959c05a5b38389df319663164
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	MYH7 MYPN PLCL2 PLCL1 RYR2	2.98e-05	192	83	5	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NES MYH10 PSIP1 CENPH PRIM1	3.05e-05	193	83	5	f25bdd10ef531b8d8441ea84573078b4b1b0f105
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYOF ABCA1 MYH10 MACF1 RYR2	3.53e-05	199	83	5	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYOF ABCA1 MYH10 MXRA5 RYR2	3.53e-05	199	83	5	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	MYOF ABCA1 MYH10 MACF1 RYR2	3.62e-05	200	83	5	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NCOA1 CCDC168 AIM2 CCDC144A	1.44e-04	142	83	4	f720f13b339589fa924a42e89393e5db0b26300b
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 TMOD1 PREPL GOLGA3	2.02e-04	155	83	4	441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	MYH10 DIRAS3 RYR2 PDZRN4	2.27e-04	160	83	4	fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CENPC TTC21B PLCL1 OGA	2.68e-04	167	83	4	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACACA CENPH PLCL2 AIM2	2.74e-04	168	83	4	4c402a1613fcf0a6e4d9b9d5551812940e91ff32
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH7 MYPN PLCL1 RYR2	2.87e-04	170	83	4	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PARP6 KDM3A SETDB2 OGA	3.00e-04	172	83	4	965a9f62b73a7e3531c343121a7c507b7e1bfe05
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACACA TDP1 SAPCD1 PDZRN4	3.06e-04	173	83	4	8bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACACA TDP1 SAPCD1 PDZRN4	3.06e-04	173	83	4	3e3c61468e703330788a10d850ef41a85680f86d
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYH10 PLCL1 RYR2 PDZRN4	3.06e-04	173	83	4	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	MXRA5 CCDC168 DIRAS3 RYR2	3.27e-04	176	83	4	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KTN1 MACF1 GOLGA3 RYR2	3.27e-04	176	83	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NES MYH10 MXRA5 BEND6	3.27e-04	176	83	4	bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	MXRA5 CCDC168 DIRAS3 RYR2	3.27e-04	176	83	4	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|343B / Donor, Lineage, Cell class and subclass (all cells)	MYH10 MXRA5 DIRAS3 RYR2	3.34e-04	177	83	4	e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	MYH10 MXRA5 DIRAS3 RYR2	3.34e-04	177	83	4	43ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYPN TMOD1 PLCL1 RYR2	3.41e-04	178	83	4	8ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYPN TMOD1 PLCL1 RYR2	3.41e-04	178	83	4	6c91331196696e0cf239d105f458e3230659fa38
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AKAP5 INHBA TMOD1 CCDC144A	3.48e-04	179	83	4	9ba8693fba2175bca9ff9735cc04e657abeb9084
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	MYH10 TMOD1 RYR2 PDZRN4	3.56e-04	180	83	4	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	MYH7 MYPN XRCC4 RYR2	3.71e-04	182	83	4	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	COVID-19-Heart-CM_4\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYPN TMOD1 PLCL1 RYR2	3.79e-04	183	83	4	2902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EXPH5 TMOD1 ANKRD18B CCDC144A	3.79e-04	183	83	4	1645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ILF3 VPS35 TDP1 MGA	3.87e-04	184	83	4	9cbfb9f09476b4d09eb8f92c6f21e449dabcfa98
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	MYH7 MYPN PLCL1 RYR2	3.87e-04	184	83	4	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH7 MYPN TMOD1 RYR2	3.87e-04	184	83	4	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYOF TMOD1 PLCL1 RYR2	3.87e-04	184	83	4	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH7 MYPN PLCL1 RYR2	3.95e-04	185	83	4	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NES EXPH5 TMOD1 ACTN4	3.95e-04	185	83	4	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NES EXPH5 TMOD1 ACTN4	3.95e-04	185	83	4	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	MYH7 MYPN PLCL1 RYR2	3.95e-04	185	83	4	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	LPS_only-Hematopoietic_Meg-Ery-Erythroid-Erythroid\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MACO1 PLCL2 TMOD1 SLC30A1	4.03e-04	186	83	4	e5014443e9d6e25943308483e20d48b776ae5373
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN RYR2 PDZRN4	4.03e-04	186	83	4	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN RYR2 PDZRN4	4.03e-04	186	83	4	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	droplet-Marrow-nan-21m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 PSIP1 CENPH TMOD1	4.03e-04	186	83	4	6e6998f5ccb1b2628048a21e8d3053e020569aba
ToppCell	LPS_only-Hematopoietic_Meg-Ery-Erythroid\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MACO1 PLCL2 TMOD1 SLC30A1	4.03e-04	186	83	4	affc246a1091e44dc85a5e237c778a7541d5a2b4
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NES PLCL1 RYR2 PDZRN4	4.03e-04	186	83	4	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	LPS_only-Hematopoietic_Meg-Ery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MACO1 PLCL2 TMOD1 SLC30A1	4.03e-04	186	83	4	40d1e15402fdfb3b5ae850a2070cd4b68fda3159
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NES PLCL1 RYR2 PDZRN4	4.03e-04	186	83	4	a95744b8649096bd7cfc3591a02841fa411085b3
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	MYH10 TMOD1 RYR2 PDZRN4	4.11e-04	187	83	4	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN TMOD1 RYR2	4.19e-04	188	83	4	90dc0e15798d0b984518ad58c7e416e30aff687a
ToppCell	Fibroblast-E_(Early_Fibroblastic_progenitor)\|World / shred on cell class and cell subclass (v4)	MYH10 PSIP1 CENPH PRIM1	4.19e-04	188	83	4	be3db9768364568f44e32ae6b3bf99e49b0978bb
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN TMOD1 RYR2	4.19e-04	188	83	4	f63dfd076ced81013918363282ae25cbbd8948ae
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN TMOD1 RYR2	4.19e-04	188	83	4	0554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 SALL3 VPS35 MACF1	4.28e-04	189	83	4	6dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	MYH7 PLCL2 PLCL1 RYR2	4.28e-04	189	83	4	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SALL3 KIAA1549L INHBA TMOD1	4.28e-04	189	83	4	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	facs-Heart-LA/RA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN TMOD1 RYR2	4.28e-04	189	83	4	a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 PSIP1 CENPH PRIM1	4.28e-04	189	83	4	16dfc37d8d390ed7f927bc844c47c9c5a89a0928
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 PSIP1 CENPH PRIM1	4.28e-04	189	83	4	3ade3fa9369e85304b20d7233b581f18ad5ecc89
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	MYOF MYH10 MACF1 PDZRN4	4.28e-04	189	83	4	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 SALL3 VPS35 MACF1	4.28e-04	189	83	4	3ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 SALL3 VPS35 MACF1	4.28e-04	189	83	4	875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCell	facs-Heart-LA/RA\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN TMOD1 RYR2	4.28e-04	189	83	4	efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCell	facs-Brain_Myeloid-Striatum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 SALL3 VPS35 MACF1	4.28e-04	189	83	4	97ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	MYH7 PLCL2 PLCL1 RYR2	4.36e-04	190	83	4	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH7 MYPN TMOD1 RYR2	4.36e-04	190	83	4	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	MYOF GSE1 AIM2 PDZRN4	4.36e-04	190	83	4	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	GSE1 NCOA1 MACF1 OGA	4.36e-04	190	83	4	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	MYH7 PLCL2 PLCL1 RYR2	4.36e-04	190	83	4	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MYOF MXRA5 INHBA RYR2	4.45e-04	191	83	4	156b467187331ac6ca390d6ca861d9670bb7b956
ToppCell	droplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN TMOD1 RYR2	4.45e-04	191	83	4	97fb4232417a39801e87725755fd16a57c250209
ToppCell	droplet-Heart-nan-3m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH7 MYPN TMOD1 RYR2	4.45e-04	191	83	4	64070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCell	droplet-Heart-nan-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYPN TMOD1 RYR2 PDZRN4	4.54e-04	192	83	4	0bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell	droplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYPN TMOD1 RYR2 PDZRN4	4.54e-04	192	83	4	d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	MYH7 MYPN PLCL1 RYR2	4.63e-04	193	83	4	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MYOF MXRA5 INHBA PLCL1	4.63e-04	193	83	4	cd45118ced91b10baed3b1068d4673ec99824b86
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PARP6 MYH10 MINAR1 NPM2	4.63e-04	193	83	4	088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NES RNF168 CENPH PRIM1	4.72e-04	194	83	4	ae6d5cf4c825b29e677296df2c0985431c83b82e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GSE1 MACF1 ACTN4 MINAR1	4.72e-04	194	83	4	24837a27b0041fe8c348225fa8b09b127d743603
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH10 PSIP1 CENPH PRIM1	4.72e-04	194	83	4	af4bbb2deb5a3913eb58990690fc3c62fbc3708c
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	EVI5 KDM3A ABCA1 PDCD11	4.72e-04	194	83	4	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 TMOD1 RYR2 PDZRN4	4.72e-04	194	83	4	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	EVI5 KDM3A ABCA1 PDCD11	4.72e-04	194	83	4	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 TMOD1 RYR2 PDZRN4	4.72e-04	194	83	4	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	MYH7 MYPN PLCL1 RYR2	4.81e-04	195	83	4	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	MYH7 MYPN PLCL1 RYR2	4.81e-04	195	83	4	75fc81bddb246dca3b437fb60827b1d4fe416405
Disease	fornix volume measurement	EVI5 PLCL1	1.44e-04	7	78	2	EFO_0803381
Disease	Hypertrophic Cardiomyopathy	MYH7 MYPN RYR2	4.69e-04	57	78	3	C0007194
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH7 MYPN	5.28e-04	13	78	2	DOID:397 (implicated_via_orthology)
Disease	eating disorder, bipolar disorder	AIM2 RYR2	6.15e-04	14	78	2	EFO_0005203, MONDO_0004985
Disease	response to methotrexate, neurotoxicity	MACF1 PLCL1	1.15e-03	19	78	2	EFO_0011057, GO_0031427
Disease	beverage consumption measurement	NCOA1 PLCL1 RYR2	1.40e-03	83	78	3	EFO_0010088
Disease	Hyalinosis, Segmental Glomerular	MYH10 ACTN4	2.49e-03	28	78	2	C0086432

Protein segments in the cluster

Peptide	Gene	Start	Entry
KRVQMEQPDAVPAQK	TTC21B	866	Q7Z4L5
PIQMKPADSEKNNAV	CELF1	91	Q92879
VKPEQKQMVAQQESI	AIM2	131	O14862
PDEMNNSPNFEEKKK	GSE1	851	Q14687
TEEQMAQQPPKGQAQ	GRAMD4	136	Q6IC98
PPSQEVNDAIKQMKK	ABCA1	1546	O95477
PQKTIQEMQQKLEDF	ACTN4	321	O43707
NDNQETAAMKPENLK	ANKRD18B	266	A2A2Z9
AKMQLDNPSKVQQAE	ACACA	816	Q13085
DKAVKPAMNQNEVQE	BEND6	221	Q5SZJ8
DVPNSQPEMVEAVKK	INHBA	46	P08476
NEAMQPTANEVEQPK	PDZRN4	516	Q6ZMN7
VKEDQVMQQNPPKFD	MYH7	71	P12883
SQPEKMSQEPEINKD	POTEF	396	A5A3E0
KPQDPMEQNVAELLQ	MAGEE1	486	Q9HCI5
KVMEQQSNLQPEAKE	MGA	2146	Q8IWI9
LPPEQQMLQKQEKEA	MACO1	201	Q8N5G2
PMKENQPNEVPEDNL	CSNKA2IP	536	A0A1B0GTH6
KDPPKKNAMNELQDE	EVI5	551	O60447
NQGAMNPLEKEIQEP	NES	856	P48681
KMDQTNKAGEIPQPV	EXPH5	716	Q8NEV8
VSEQPNKDVVEQMEK	KTN1	721	Q86UP2
QDETQQLQPDMSKLP	TUBGCP6	51	Q96RT7
PQNVMAQQKVTKEEA	KIAA1549L	1311	Q6ZVL6
LSKQPVGNQEMENLK	GOLGA3	1276	Q08378
KEQVDPLQMKLQQVN	MACF1	5281	Q9UPN3
GQMLQKEPEEEQQKQ	PASD1	551	Q8IV76
KVSENSQPEKMSQEP	POTEB3	391	A0JP26
SQPEKMSQEPEINKD	POTEB3	396	A0JP26
NNQSDLEKEMQKMNP	PRIM1	61	P49642
MAAEEPQQQKQEPLG	OTUB1	1	Q96FW1
PDPQKVLQGVIDMKN	ARMC8	31	Q8IUR7
NVNKENKEKQPTMPI	KDM3A	831	Q9Y4C1
EKTPEQIMQEKQIEA	CENPH	66	Q9H3R5
TKPQQLQEEMKELQQ	EFCAB6	936	Q5THR3
KNEDNIMTAQNVPLK	CENPC	641	Q03188
KQSDIKKPENTQPEN	CEP97	511	Q8IW35
RVNINVPMKTEQKQE	CUL1	681	Q13616
QEDPPLMVKKNSVVQ	C3orf20	766	Q8ND61
QKKEEKAEPPQAMNA	ILF3	391	Q12906
ENKQPQKTSQEPEMA	CCDC144B	241	Q3MJ40
KQQKPLEGEMQPAIN	AKAP5	96	P24588
APQNIEEQDIVMKKQ	CCDC168	5821	Q8NDH2
DPQPFAVDKQQMQKL	CCDC168	6206	Q8NDH2
ENKQPQKTSQEPEMA	CCDC144A	241	A2RUR9
LQEPEKKSQMPNTTE	DIRAS3	206	O95661
QLVENIDKKMTDPNQ	SALL3	666	Q9BXA9
PMPEVQEKFQEQKAK	RYR2	4411	Q92736
PPANQEDKKMQPVTI	NPM2	66	Q86SE8
SPPQEMSQEDLKEKN	MAP3K19	91	Q56UN5
PIPGQQDKDNFQETM	MYH10	316	P35580
QNQPKADKDESTMIN	PRR14L	1431	Q5THK1
ANINTQDPKIQKEIM	PARP6	606	Q2NL67
KVSENSQPEKMSQEP	POTEC	391	B2RU33
SQPEKMSQEPEINKD	POTEC	396	B2RU33
DQKMQQPEKVSVQID	MINAR1	631	Q9UPX6
KVSENSQPEKMSQEP	POTED	391	Q86YR6
SQPEKMSQEPEINKD	POTED	396	Q86YR6
PANQKKMEETIPDQQ	MEIOC	376	A2RUB1
PMQTDEQTNKEQFVP	OGA	526	O60502
EKKEQMDPCNTNPTP	NCOA1	776	Q15788
MGKENMEQPNNVPVK	PLCL2	596	Q9UPR0
SQPEKMSQEPEINKD	POTEI	396	P0CG38
RQQKGVTQPKEEMAQ	SAPCD1	121	Q5SSQ6
LDQQEKQPELPEQQM	IVL	296	P07476
VPPITVNAKMNKDVN	CLCA4	591	Q14CN2
QMETEQQNKDEGKKP	PSIP1	321	O75475
DVNMKPVVQEPNQKV	MRPL19	201	P49406
EMPSKEKQQPQKPQA	PDCD11	1451	Q14690
PEQKKVAQDMTQPLS	PLCL1	391	Q15111
LQPEMPQKQAEKVVI	TDP1	96	Q9NUW8
MNQAKVPVDGNKEEP	CTPS2	126	Q9NRF8
EDKESQPQMPKQNPV	TRIM24	426	O15164
SDPMPVTQKEQENKS	SETDB2	81	Q96T68
KIDNQSQPLGNKVEM	TMOD1	286	P28289
NKKNDEMQEVPNRVL	SPANXN3	21	Q5MJ09
MPTTQQSPQDEQEKL	VPS35	1	Q96QK1
GTEPKMAPQENQLQE	XRCC4	281	Q13426
IDQKMPDIEPNSENN	ZNF654	956	Q8IZM8
QPVKQENEKPLPENM	PREPL	76	Q4J6C6
MDTQKDVQPPKQQPM	POLR2K	1	P53803
LQLQKEVDKEQMVPN	RNF168	451	Q8IYW5
KPQLSMPQKSDNGEV	ZNF484	816	Q5JVG2
MEDPNPEENMKQQDS	ZNF576	1	Q9H609
VVIEIKNMPNKQPES	SLC30A1	491	Q9Y6M5
DQQEHVVPKSQPKTM	USP6	236	P35125
NTPKQLEMEKNAEPT	MXRA5	1211	Q9NR99
QNPPKVIMELFDNDQ	MYOF	1206	Q9NZM1
NKEEMNRIQKPNEVS	MYPN	371	Q86TC9