Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Domain-

SEMA4D SEMA3D ANOS1 MYOM3 OSMR CAMTA1 CRLF2 BTN3A2 BTN3A1 ADGRA3

1.22e-0566352102.60.40.10
DomainIg-like_fold

SEMA4D SEMA3D ANOS1 MYOM3 OSMR CAMTA1 CRLF2 BTN3A2 BTN3A1 ADGRA3

2.10e-057065210IPR013783
DomainTRYPSIN_HIS

TMPRSS6 CTRL KLKB1 TMPRSS11B

1.93e-04103524IPR018114
DomainTRYPSIN_SER

TMPRSS6 CTRL KLKB1 TMPRSS11B

2.15e-04106524PS00135
DomainTRYPSIN_HIS

TMPRSS6 CTRL KLKB1 TMPRSS11B

2.23e-04107524PS00134
DomainPeptidase_S1A

TMPRSS6 CTRL KLKB1 TMPRSS11B

2.75e-04113524IPR001314
DomainTRYPSIN_DOM

TMPRSS6 CTRL KLKB1 TMPRSS11B

2.94e-04115524PS50240
DomainTryp_SPc

TMPRSS6 CTRL KLKB1 TMPRSS11B

3.14e-04117524SM00020
DomainTrypsin

TMPRSS6 CTRL KLKB1 TMPRSS11B

3.57e-04121524PF00089
DomainTrypsin_dom

TMPRSS6 CTRL KLKB1 TMPRSS11B

3.57e-04121524IPR001254
DomainPeptidase_S1_PA

TMPRSS6 CTRL KLKB1 TMPRSS11B

3.80e-04123524IPR009003
Domain-

TMPRSS6 TMPRSS11B

7.80e-04155223.30.70.960
DomainIG

SEMA4D SEMA3D MYOM3 BTN3A2 BTN3A1 ADGRA3

1.07e-03421526SM00409
DomainIg_sub

SEMA4D SEMA3D MYOM3 BTN3A2 BTN3A1 ADGRA3

1.07e-03421526IPR003599
DomainZZ

MIB2 UTRN

1.13e-0318522PF00569
DomainZF_ZZ_2

MIB2 UTRN

1.13e-0318522PS50135
DomainZF_ZZ_1

MIB2 UTRN

1.13e-0318522PS01357
DomainZnf_ZZ

MIB2 UTRN

1.26e-0319522IPR000433
DomainZnF_ZZ

MIB2 UTRN

1.26e-0319522SM00291
DomainSemaphorin

SEMA4D SEMA3D

1.40e-0320522IPR027231
DomainSEA

TMPRSS6 TMPRSS11B

1.69e-0322522PF01390
DomainFN3

ANOS1 MYOM3 OSMR CRLF2

1.74e-03185524SM00060
DomainSPRY

RNF123 HERC1 BTN3A1

1.83e-0387523SM00449
DomainSEA

TMPRSS6 TMPRSS11B

1.85e-0323522PS50024
DomainSEA_dom

TMPRSS6 TMPRSS11B

1.85e-0323522IPR000082
DomainTRYPSIN_SER

TMPRSS6 CTRL KLKB1

2.02e-0390523IPR033116
DomainFN3

ANOS1 MYOM3 OSMR CRLF2

2.27e-03199524PS50853
DomainSPRY

RNF123 HERC1 BTN3A1

2.28e-0394523PF00622
DomainSPRY_dom

RNF123 HERC1 BTN3A1

2.28e-0394523IPR003877
DomainIG_LIKE

SEMA4D SEMA3D MYOM3 BTN3A2 BTN3A1 ADGRA3

2.34e-03491526PS50835
DomainB30.2/SPRY

RNF123 HERC1 BTN3A1

2.35e-0395523IPR001870
DomainB302_SPRY

RNF123 HERC1 BTN3A1

2.35e-0395523PS50188
DomainIg-like_dom

SEMA4D SEMA3D MYOM3 BTN3A2 BTN3A1 ADGRA3

2.64e-03503526IPR007110
DomainFN3_dom

ANOS1 MYOM3 OSMR CRLF2

2.71e-03209524IPR003961
DomainSema

SEMA4D SEMA3D

3.36e-0331522SM00630
DomainSemap_dom

SEMA4D SEMA3D

3.36e-0331522IPR001627
DomainSema

SEMA4D SEMA3D

3.36e-0331522PF01403
DomainSEMA

SEMA4D SEMA3D

3.36e-0331522PS51004
DomainPSI

SEMA4D SEMA3D

3.57e-0332522PF01437
DomainPlexin_repeat

SEMA4D SEMA3D

3.57e-0332522IPR002165
DomainLRRCT

TLR1 ADGRA3

3.57e-0332522PF01463
DomainPSI

SEMA4D SEMA3D

6.67e-0344522IPR016201
DomainNeurotransmitter_ion_chnl_CS

CHRNA5 GABRA5

6.97e-0345522IPR018000
DomainNeur_chan_memb

CHRNA5 GABRA5

7.28e-0346522PF02932
DomainPSI

SEMA4D SEMA3D

7.28e-0346522SM00423
DomainNeur_chan_LBD

CHRNA5 GABRA5

7.59e-0347522PF02931
DomainNEUROTR_ION_CHANNEL

CHRNA5 GABRA5

7.59e-0347522PS00236
DomainNeurotrans-gated_channel_TM

CHRNA5 GABRA5

7.59e-0347522IPR006029
Domain-

CHRNA5 GABRA5

7.59e-03475222.70.170.10
DomainNeur_channel

CHRNA5 GABRA5

7.59e-0347522IPR006201
DomainNeur_chan_lig-bd

CHRNA5 GABRA5

7.59e-0347522IPR006202
Domainfn3

ANOS1 MYOM3 OSMR

1.04e-02162523PF00041
Pubmed

Differential role for CD277 as a co-regulator of the immune signal in T and NK cells.

BTN3A2 BTN3A1

2.37e-06254221918970
Pubmed

The molecular basis for modulation of human Vγ9Vδ2 T cell responses by CD277/butyrophilin-3 (BTN3A)-specific antibodies.

BTN3A2 BTN3A1

2.37e-06254222846996
Pubmed

CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells.

BTN3A2 BTN3A1

2.37e-06254221113407
Pubmed

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset.

BTN3A2 BTN3A1

7.09e-06354222767497
Pubmed

Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2.

BTN3A2 BTN3A1

1.42e-05454239142074
Pubmed

Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex.

BTN3A2 BTN3A1

1.42e-0545429382921
Pubmed

Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology.

BTN3A2 BTN3A1

2.36e-05554229339503
Pubmed

The cluster of BTN genes in the extended major histocompatibility complex.

BTN3A2 BTN3A1

4.94e-05754211170752
Pubmed

Netrin 1 and Dcc signalling are required for confinement of central axons within the central nervous system.

BARHL2 NTN1

4.94e-05754224449837
Pubmed

A molecular program for contralateral trajectory: Rig-1 control by LIM homeodomain transcription factors.

BARHL2 NTN1

6.59e-05854218701067
Pubmed

An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.

SEMA4D SEMA3D NTN1

7.41e-055254326633812
Pubmed

Common variants on chromosome 6p22.1 are associated with schizophrenia.

BTN3A2 BTN3A1

1.29e-041154219571809
Pubmed

Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting.

SEMA3D NTN1

1.55e-041254219812329
Pubmed

Netrin1/DCC signaling promotes neuronal migration in the dorsal spinal cord.

BARHL2 NTN1

1.55e-041254227784329
Pubmed

BARHL2 transcription factor regulates the ipsilateral/contralateral subtype divergence in postmitotic dI1 neurons of the developing spinal cord.

BARHL2 NTN1

2.80e-041654222307612
Pubmed

A 1.1-Mb transcript map of the hereditary hemochromatosis locus.

BTN3A2 BTN3A1

3.56e-04185429149941
Pubmed

Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.

LMNB1 EIF3D UTRN

3.78e-049054331280863
Pubmed

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.

SEMA4D NTN1

4.42e-042054222863734
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

RNF123 MIB2 HERC1

4.43e-049554329643511
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

USP34 B4GALNT1 ITPRIPL2 OSMR MBOAT2 BTN3A2 CHRNA5 ADGRA3

5.01e-04120154835696571
Pubmed

A semaphorin code defines subpopulations of spinal motor neurons during mouse development.

SEMA4D SEMA3D

6.39e-042454215869472
Pubmed

A single-cell time-lapse of mouse prenatal development from gastrula to birth.

SEMA3D NTN1

6.94e-042554238355799
Pubmed

TLR5 Supports Development of Placental Labyrinthine Zone in Mice.

LMNB1 TLR1

7.51e-042654234395439
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

SEMA4D SEMA3D

8.72e-042854218617019
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

RNF123 LMNB1 CEP95 MYOM3 EIF3D UTRN

9.59e-0473654629676528
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

SEMA4D SEMA3D NTN1

1.01e-0312654316284245
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

USP34 CLASP1 CAMTA1

1.05e-0312854330995482
Pubmed

Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.

SEMA3D NTN1

1.07e-033154222076636
Pubmed

The zinc-finger transcription factor GLI3 is a regulator of precerebellar neuronal migration.

BARHL2 NTN1

1.07e-033154230470704
Pubmed

c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections.

NTN1 GABRA5

1.14e-033254222514301
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

USP34 ITPRIPL2 CLASP1 ACAD10 OSMR HERC1 ADGRA3

1.22e-03106154733845483
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 ITPRIPL2 MYOM3 TBC1D25 MIB2 HERC1 BTN3A2

1.54e-03110554735748872
Cytoband5q23.2

LMNB1 ZNF608

6.58e-04325425q23.2
CytobandEnsembl 112 genes in cytogenetic band chr1p36

CFAP107 MYOM3 MIB2 CAMTA1 ARHGEF16

1.23e-03681545chr1p36
GeneFamilyFibronectin type III domain containing

ANOS1 PTPRQ MYOM3 OSMR CRLF2

1.77e-05160375555
GeneFamilyButyrophilins|V-set domain containing|C2-set domain containing

BTN3A2 BTN3A1

4.21e-0415372458
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

MIB2 UTRN

6.11e-041837291
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA4D SEMA3D

7.56e-0420372736
GeneFamilyAdenosine receptors|V-set domain containing

SEMA3D BTN3A2 BTN3A1

4.46e-03163373590
GeneFamilyProteases, serine

TMPRSS6 TMPRSS11B

7.36e-0363372738
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3|Liver / Manually curated celltypes from each tissue

B4GALNT1 ZNF608 PKDCC AK9 CRLF2

1.61e-061635457f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA3D B4GALNT1 ZNF608 NTN1 CRLF2

2.62e-0618054532d871738a24071b70084a7e80148a516110c78b
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SEMA3D B4GALNT1 ZNF608 NTN1 CRLF2

2.62e-06180545067ca8a15228c7f3b3bc7aecbc9b1611ca05e176
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 ACAD10 ABCC2 KLKB1 ADGRA3

2.84e-06183545d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANOS1 ZNF608 THSD7B UTRN SLC35F4

3.77e-061945455d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANOS1 ZNF608 THSD7B UTRN SLC35F4

3.77e-061945456ac759828c41ffa974ee82842162caa959351dd1
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDK4 CRYBG3 SPATA1 ADGRA3

1.72e-05127544353484362448f27e8377447d0c26391b1da7acc5
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CCDC30 KLKB1 THAP9 ADGRA3

3.75e-05155544c4dc0fa1d0e657753a56939eb4829fb60382c17f
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 MYOM3 PNLDC1 FETUB

4.04e-051585449f58428f70d1427b20122c5c1cc7bf521d0f4832
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 ABCC2 KLKB1 FETUB

4.24e-05160544c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRQ TENM1 ABCC2 KLKB1

4.45e-05162544bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellfacs-Lung-Endomucin-24m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDK4 CTRL TNP2 GABRA5

4.89e-0516654464a0762eb9cafb6a079df296ed677c8e0ae0efa7
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 ABCC2 KLKB1 FETUB

5.13e-05168544b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 ABCC2 KLKB1 FETUB

5.13e-05168544073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SEMA3D ZNF608 GJB4 NTN1

5.25e-05169544e3410ccb3f85811c75694e286115803911169a2f
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 ABCC2 KLKB1 FETUB

5.25e-05169544f195467438c589f87224bde7da720dea072d110c
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA3D ZNF608 GJB4 NTN1

5.25e-05169544a4f610d07c3ba5537f4497f523669b914f7eddc1
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 ABCC2 KLKB1 FETUB

5.25e-051695447785cab967a33560830c394c918d6ce625103858
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF123 TMEM63C CRLF2 FETUB

5.49e-05171544eddc5e05003382603ee49f74b9e2242a43021096
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B4GALNT1 TMPRSS6 NTN1 CTRL

5.75e-05173544f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B4GALNT1 TMPRSS6 NTN1 CTRL

5.75e-05173544c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 ABCC2 KLKB1 FETUB

6.01e-051755445c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCellClub_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

ZNF608 TMEM63C NTN1 MBOAT2

6.14e-0517654488c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANOS1 PTPRQ PKDCC UTRN

6.28e-051775449af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-4|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

SEMA3D ANOS1 TLR1 THSD7B

6.70e-05180544886ebaf9cf8992e8dd13fca799a1d1a2a9ce73d8
ToppCell10x5'-Lung-Myeloid_Dendritic-migDC|Lung / Manually curated celltypes from each tissue

B4GALNT1 NTN1 MBOAT2 CRLF2

6.70e-05180544e9e8992deb0beeee5548910e4616e7c990763d99
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TENM1 UTRN KLKB1 SLC35F4

6.85e-05181544bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANOS1 PTPRQ PKDCC UTRN

6.85e-05181544b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 ACAD10 ABCC2 KLKB1

7.00e-05182544770ce9f3f4538d0181a0181543841bc964c68274
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 ACAD10 ABCC2 KLKB1

7.00e-0518254477ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 ACAD10 ABCC2 KLKB1

7.00e-051825444921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMPRSS6 MYOM3 ARHGEF16 MBOAT2

7.30e-051845449365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMPRSS6 MYOM3 ARHGEF16 MBOAT2

7.30e-05184544204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ANOS1 PTPRQ PKDCC UTRN

7.30e-0518454457c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TENM1 THSD7B UTRN SLC35F4

7.30e-051845447d41784eac0935e77d6bc701f20c693adf998730
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ANOS1 PTPRQ PKDCC UTRN

7.30e-05184544d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCelldroplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 MYOM3 ARHGEF16 MBOAT2

7.30e-051845447cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCelldroplet-Lung-nan-21m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 MYOM3 ARHGEF16 MBOAT2

7.30e-0518454453b71c4ac86dc5e42763b8f64fbc917177531017
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANOS1 PTPRQ PKDCC UTRN

7.61e-051865443aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANOS1 ZNF608 PTPRQ PKDCC

7.77e-051875444ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellMild-Myeloid-mDC-|Mild / Condition, Lineage, Cell class and cell subclass

SEMA3D LMNB1 ZNF608 CRLF2

8.60e-051925448520b3fdf4508ac66f7918da613abc928ab5832a
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANOS1 ZNF608 THSD7B SLC35F4

8.60e-05192544f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCellMild-Myeloid-mDC|Mild / Condition, Lineage, Cell class and cell subclass

SEMA3D LMNB1 ZNF608 CRLF2

8.60e-05192544da3952bd5c96242c15eb76678d0608ae2926a16e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LMNB1 ZNF608 NTN1 CRLF2

8.60e-051925442c69f3f388b69fb1c1968c923cdbab90658883dd
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANOS1 ZNF608 THSD7B SLC35F4

8.60e-05192544690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LMNB1 ZNF608 NTN1 CRLF2

8.60e-05192544d5a7b546ebfb2e757dd9c64cb1b651f6ed0e0fc7
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF608 TENM1 THSD7B SLC35F4

8.60e-05192544bf1943715085c4124b1675888b0615c9500ec888
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

B4GALNT1 ZNF608 MBOAT2 CRLF2

8.78e-05193544a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANOS1 ZNF608 UTRN SLC35F4

8.78e-05193544294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SEMA4D TENM1 UTRN BTN3A1

8.78e-05193544a594f89a18273797506287d9e22f72abe53e4920
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

B4GALNT1 ZNF608 MBOAT2 CRLF2

8.78e-051935447426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANOS1 ZNF608 UTRN SLC35F4

8.78e-051935443d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_9|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LMNB1 ZNF608 PDK4 CRLF2

8.78e-051935447842f29c16fe3a289ed3861fa570430142d2363f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF608 TENM1 THSD7B SLC35F4

8.95e-0519454402a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCellBAL-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA3D LMNB1 MBOAT2 CRLF2

9.13e-051955449e5cf33b5dd455efa464a63d7116786c0786aefd
ToppCellBAL-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SEMA3D LMNB1 MBOAT2 CRLF2

9.13e-051955446ba23e19801305e071b0e4aaf1ee6f53f3b027d3
ToppCellMild_COVID-19-Myeloid-cDC|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

SEMA3D LMNB1 MBOAT2 CRLF2

9.13e-0519554424149bb6933135b1a0a5c7f505914942b3782c3a
ToppCellBAL-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA3D LMNB1 MBOAT2 CRLF2

9.13e-0519554466e5fd9f3208a06d617c5e994822bf57dceae7e2
ToppCellBAL-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SEMA3D LMNB1 MBOAT2 CRLF2

9.13e-051955447209babdff96c93cd52cfe5d5cfd7e3c0274d8dd
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF608 TENM1 THSD7B SLC35F4

9.32e-051965447af6c5147ac859353504d19727dbe24f63a29dd4
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D PKDCC NTN1 OSMR

9.32e-05196544e386526332138e636aef2542c11316347a45689c
ToppCellLPS_IL1RA_TNF|World / Treatment groups by lineage, cell group, cell type

SEMA3D ANOS1 ACAD10 UTRN

9.50e-051975440a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANOS1 PTPRQ CAMTA1 UTRN

9.50e-05197544b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 TENM1 HERC1 UTRN

9.50e-0519754457ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANOS1 PTPRQ ACAD10 UTRN

9.69e-051985445a85c286f79cde5811d2595a3397c6fb7685adee
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANOS1 ZNF608 NTN1 MBOAT2

9.69e-051985441408e02e053ad3406229bfe8189da03be6366e81
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANOS1 ZNF608 NTN1 MBOAT2

9.69e-05198544af399569c718f5fd971d73a7926768c9311002a3
ToppCellCOVID-19-Myeloid-Migratory_DC|Myeloid / Condition, Lineage and Cell class

LMNB1 ZNF608 MBOAT2 CRLF2

9.69e-0519854490f3b227cbc61c268d6d94bc9945a08d83d2d3d5
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 TENM1 HERC1 UTRN

9.88e-05199544f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

USP34 CLASP1 HERC1 UTRN

9.88e-0519954494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANOS1 PTPRQ PKDCC UTRN

9.88e-05199544d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ANOS1 TMPRSS6 ARHGEF16 GABRA5

9.88e-05199544995d710d7302272e7951a5a5d766d1039089ee2b
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ANOS1 TMPRSS6 ARHGEF16 GABRA5

9.88e-05199544e9c47f565a0a7737ecff68569d668aeb707ae5a6
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANOS1 ZNF608 TENM1 CRYBG3

1.01e-04200544f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANOS1 ZNF608 TENM1 CRYBG3

1.01e-042005441639982d9d994918f7912d12d9d7cfcbc9da4145
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-LGR5--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

TENM1 THSD7B KLKB1 SLC35F4

1.01e-042005448c1d4fffa5abe89ee2ff84fed2dfa97c779bde04
ToppCellNeuronal-Inhibitory|Neuronal / cells hierarchy compared to all cells using T-Statistic

ZNF608 TENM1 THSD7B SLC35F4

1.01e-042005449ff8647e2de0b538e15929dca88ebb20ff7ab043
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-LGR5-|Neuronal / cells hierarchy compared to all cells using T-Statistic

TENM1 THSD7B KLKB1 SLC35F4

1.01e-042005441026b4ede4ea61d01ea942164b37a08c8c8234ff
ToppCelldistal-2-Epithelial-Alveolar_Epithelial_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANOS1 TMPRSS6 PTPRQ PKDCC

1.01e-04200544313ec1e53bd738a9cb48dc5b946261156f99f44b
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA4D GJB4 TENM1 BTN3A1

1.01e-04200544510d84bf7a4621b079e5a7330d25e04508c84a49
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANOS1 ZNF608 THSD7B UTRN

1.01e-04200544d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANOS1 ZNF608 TENM1 CRYBG3

1.01e-0420054470a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANOS1 ZNF608 THSD7B UTRN

1.01e-04200544862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANOS1 PTPRQ PKDCC UTRN

1.01e-042005448683445ad5b70748c4a1f12eb77d47623085147e
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANOS1 ZNF608 THSD7B UTRN

1.01e-04200544a91345f268f13170c27309333603eb82400c9947
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-ILC|Multiple_Sclerosis / Disease, condition lineage and cell class

DUS2 RNF123 TLR1 MBOAT2

1.01e-04200544ab9bdc9365cbdffe4ed246ce0c8a008a390e387e
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-LGR5|Neuronal / cells hierarchy compared to all cells using T-Statistic

TENM1 THSD7B KLKB1 SLC35F4

1.01e-0420054472c9cd872074b60f62685a95eab83c41e609eb6e
ComputationalNeighborhood of CASP8

SEMA4D BTN3A2 BTN3A1

3.97e-0527273GNF2_CASP8
ComputationalNeighborhood of SNRK

SEMA4D BTN3A2 BTN3A1

4.44e-0528273GNF2_SNRK
ComputationalNeighborhood of ITGAL

SEMA4D BTN3A2 BTN3A1

3.40e-0455273GNF2_ITGAL
Diseasebipolar disorder

CLASP1 MYOM3 TMEM63C BTN3A2 BTN3A1 CHRNA5 SLC35F4

5.79e-05577517MONDO_0004985
Diseasedipeptidase 2 measurement

DUS2 KLKB1

1.31e-0410512EFO_0801528
Diseasepersulfide dioxygenase ETHE1, mitochondrial measurement

KLKB1 FETUB

1.91e-0412512EFO_0008258
Diseasemuscular dystrophy (implicated_via_orthology)

LMNB1 UTRN

6.02e-0421512DOID:9884 (implicated_via_orthology)
DiseaseVisual seizure

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0270824
DiseaseEpileptic drop attack

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0270846
DiseaseGeneralized seizures

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0234533
DiseaseClonic Seizures

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0234535
DiseaseVertiginous seizure

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0422855
DiseaseGustatory seizure

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0422854
DiseaseSeizures, Somatosensory

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0422850
DiseaseOlfactory seizure

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0422853
DiseaseSeizures, Auditory

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0422852
DiseaseGeneralized Absence Seizures

ABCC2 CHRNA5 GABRA5

7.19e-04101513C4505436
DiseaseConvulsive Seizures

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0751494
DiseaseSeizures, Sensory

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0751496
DiseaseJacksonian Seizure

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0022333
DiseaseNon-epileptic convulsion

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0751056
DiseaseAtonic Absence Seizures

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0751123
DiseaseComplex partial seizures

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0149958
DiseaseSingle Seizure

ABCC2 CHRNA5 GABRA5

7.19e-04101513C0751110
DiseaseEpileptic Seizures

ABCC2 CHRNA5 GABRA5

7.19e-04101513C4317109
DiseaseNonepileptic Seizures

ABCC2 CHRNA5 GABRA5

7.19e-04101513C3495874
DiseaseTonic Seizures

ABCC2 CHRNA5 GABRA5

7.40e-04102513C0270844
DiseaseAbsence Seizures

ABCC2 CHRNA5 GABRA5

7.40e-04102513C4316903
DiseaseConvulsions

ABCC2 CHRNA5 GABRA5

7.40e-04102513C4048158
DiseaseSeizures, Focal

ABCC2 CHRNA5 GABRA5

7.83e-04104513C0751495
DiseaseMyoclonic Seizures

ABCC2 CHRNA5 GABRA5

7.83e-04104513C4317123
DiseaseTonic - clonic seizures

ABCC2 CHRNA5 GABRA5

7.83e-04104513C0494475
Diseaselung carcinoma

AK9 MBOAT2 BTN3A2 BTN3A1 CHRNA5

1.44e-03482515EFO_0001071
Diseaseliver iron measurement

TMPRSS6 BTN3A2

1.49e-0333512EFO_0010056

Protein segments in the cluster

PeptideGeneStartEntry
VYTRVSKFSTWINQV

CTRL

246

P40313
WNSKDLYIGVSTVQV

CAMTA1

1321

Q9Y6Y1
TRSIHVKSGVWVAYQ

CRYBG3

2606

Q68DQ2
KWVSSSLRQVVNVYA

BTN3A1

66

O00481
NLAVSQVTTKYVLWV

B4GALNT1

341

Q00973
LWVGVTARNIYKQVT

ADGRA3

841

Q8IWK6
IVVKSYRPAQVTWSQ

ARHGEF16

251

Q5VV41
QVRTWVKQYRASETS

ACAD10

421

Q6JQN1
WKFTVNIISVYKQGT

NTN1

511

O95631
TSNVIWVGNYSTTVK

OSMR

76

Q99650
NTSSVQLVKSWYIQS

PDK4

81

Q16654
AITYWGQTRLKSAKV

ANOS1

376

P23352
VITWIVTQVAISYTV

MBOAT2

416

Q6ZWT7
TIRVWNVTKKQYSLQ

HERC1

3451

Q15751
SRYVLKAGQTVTIWA

LMNB1

486

P20700
QYSLFKVTRASSQWV

FETUB

186

Q9UGM5
QSSVTTIVKSYYWRV

TMEM63C

371

Q9P1W3
VVYVWTNGSTKSVVV

GABRA5

201

P31644
TIKGTTAYVPQQSWI

ABCC2

696

Q92887
TVQVTWNASKYSRTN

CRLF2

41

Q9HC73
TVYVWNRSSLKTINV

PTPRQ

931

Q9UMZ3
TSTKTVIRYNGTVTW

CHRNA5

146

P30532
SVYSWDIVVQRVGSK

EIF3D

261

O15371
WQIETKYSTKVLTGN

CFAP107

16

Q8N1D5
SGVNKYSTVLSRIWL

GJB4

11

Q9NTQ9
SNKWTISSIQSRVLY

CCDC30

581

Q5VVM6
QPWKIYSRKTTTQSL

CEP95

531

Q96GE4
KWVSSSLRQVVNVYA

BTN3A2

66

P78410
LTDTQVKTWYQNRRT

BARHL2

271

Q9NY43
TFYTNVWKIESQRNV

KLKB1

241

P03952
SIVTVAEQKYQSTLW

DUS2

401

Q9NX74
TVVVQWDQGTRTNYR

MIB2

51

Q96AX9
TQWGRILSSYVLKTV

ITPRIPL2

396

Q3MIP1
VGKTTLARYITQAWK

AK9

41

Q5TCS8
IKTWVQTRLGDYQTQ

UTRN

1091

P46939
RIQQVYKTKTRSSGW

TNP2

121

Q05952
FVVTNQTTWTGRQLV

PKDCC

456

Q504Y2
TLSKVQQVLSWSYGE

TBC1D25

176

Q3MII6
EWYLKTRQSVQQFTV

PNLDC1

41

Q8NA58
QVYWLTISSNGVLKR

TENM1

1606

Q9UKZ4
TTVEQSHTKWVRYNG

SEMA4D

346

Q92854
SSWVGTTQIVKITYK

SLC35F4

176

A4IF30
GSWNYKLNTISTEVV

SPATA1

46

Q5VX52
TTVWYFSISNVKLQG

TLR1

271

Q15399
KSQQATIKWYIQRSG

SEMA3D

616

O95025
TSWVNSSNYKVVLLG

CLASP1

56

Q7Z460
TRVTSYRNWITSKTG

TMPRSS11B

401

Q86T26
LWTVQRQYGVSVTKT

THAP9

671

Q9H5L6
NRVRKWNVTTTNYGK

RNF123

176

Q5XPI4
VVNVTWRNKTYVGTL

ZNF608

391

Q9ULD9
TLKIFTYINSWTQRQ

USP34

31

Q70CQ2
KSWAIEIGYQTRQVS

THSD7B

291

Q9C0I4
YTRITGVISWIQQVV

TMPRSS6

796

Q8IU80
YSRKVGTSEWQTVNN

MYOM3

636

Q5VTT5