Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlactate transmembrane transporter activity

SLC5A12 SLC16A3 SLC16A7 SLC16A8

9.25e-116334GO:0015129
GeneOntologyMolecularFunctionsymporter activity

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8

1.52e-07150336GO:0015293
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8 CFTR

4.20e-07293337GO:0008514
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8

1.01e-06207336GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8

1.04e-06208336GO:0005342
GeneOntologyMolecularFunctionsecondary active monocarboxylate transmembrane transporter activity

SLC5A12 SLC16A3 SLC16A7

3.91e-0619333GO:0015355
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLC5A12 SLC16A3 SLC16A7 SLC16A8

5.25e-0670334GO:1901618
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8

7.98e-06296336GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8 CFTR

1.06e-05477337GO:0022804
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLC5A12 SLC16A3 SLC16A7 SLC16A8

1.43e-0590334GO:0008028
GeneOntologyMolecularFunctionpyruvate transmembrane transporter activity

SLC16A3 SLC16A7

3.96e-056332GO:0050833
GeneOntologyMolecularFunctionretinyl-palmitate esterase activity

RPE65 CES2

9.47e-059332GO:0050253
GeneOntologyMolecularFunctiontransmembrane transporter activity

GABRG1 SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8 CFTR

5.35e-041180338GO:0022857
GeneOntologyMolecularFunctiontransporter activity

GABRG1 SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8 CFTR

9.58e-041289338GO:0005215
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC5A12 SLC16A3 SLC1A2

9.88e-04119333GO:0015294
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC5A12 SLC1A2

1.52e-0335332GO:0005343
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

GABRG1 SLC1A2 CFTR

1.96e-03151333GO:0008509
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC36A4 SLC1A2

2.09e-0341332GO:0015175
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GABRG1 CFTR

3.09e-0350332GO:0099095
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC36A4 SLC1A2

6.13e-0371332GO:0015179
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GABRG1 SLC5A12 SLC16A3 SLC1A2 CFTR

7.64e-03758335GO:0015318
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A12 SLC1A2

7.91e-0381332GO:0015370
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC36A4 SLC1A2

8.29e-0383332GO:0015101
GeneOntologyMolecularFunctionchloride channel activity

GABRG1 CFTR

8.88e-0386332GO:0005254
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GABRG1 SLC5A12 SLC16A3 SLC1A2 CFTR

9.20e-03793335GO:0015075
GeneOntologyMolecularFunctionglycosyltransferase activity

POGLUT1 HAS1 ST8SIA6

1.18e-02288333GO:0016757
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GABRG1 CFTR

1.25e-02103332GO:0005253
GeneOntologyBiologicalProcesslactate transport

SLC5A12 SLC16A3 SLC16A7 SLC16A8

6.80e-109334GO:0015727
GeneOntologyBiologicalProcesslactate transmembrane transport

SLC5A12 SLC16A3 SLC16A7 SLC16A8

6.80e-109334GO:0035873
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8

2.06e-07163336GO:1905039
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8

2.38e-07167336GO:1903825
GeneOntologyBiologicalProcessorganic anion transport

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8 CFTR

1.41e-05515337GO:0015711
GeneOntologyBiologicalProcessplasma membrane lactate transport

SLC16A3 SLC16A7

3.71e-056332GO:0035879
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8

4.18e-05410336GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8

4.30e-05412336GO:0015849
GeneOntologyBiologicalProcesspyruvate transmembrane transport

SLC16A3 SLC16A7

5.19e-057332GO:1901475
GeneOntologyBiologicalProcesspyruvate transport

SLC16A3 SLC16A7

8.87e-059332GO:0006848
GeneOntologyBiologicalProcessorganic hydroxy compound transport

SLC5A12 SLC16A3 SLC16A7 SLC16A8 CFTR

2.44e-04358335GO:0015850
GeneOntologyBiologicalProcessmonocarboxylic acid transport

SLC5A12 SLC16A3 SLC16A7 SLC16A8

3.58e-04213334GO:0015718
DomainMCT

SLC16A3 SLC16A7 SLC16A8

5.01e-085333IPR004743
DomainMFS

SLC16A3 SLC16A7 SLC16A8

3.36e-0477333IPR011701
DomainMFS_1

SLC16A3 SLC16A7 SLC16A8

3.36e-0477333PF07690
DomainMFS

SLC16A3 SLC16A7 SLC16A8

9.04e-04108333PS50850
DomainMFS_dom

SLC16A3 SLC16A7 SLC16A8

1.68e-03134333IPR020846
DomainER_TARGET

CALR3 POGLUT1

3.11e-0347332PS00014
DomainVWFA

CPNE5 VWA8

9.20e-0382332PS50234
DomainVWA

CPNE5 VWA8

9.64e-0384332SM00327
DomainVWF_A

CPNE5 VWA8

1.32e-0299332IPR002035
PathwayREACTOME_PROTON_COUPLED_MONOCARBOXYLATE_TRANSPORT

SLC16A3 SLC16A7 SLC16A8

1.11e-076263MM17217
PathwayREACTOME_PROTON_COUPLED_MONOCARBOXYLATE_TRANSPORT

SLC16A3 SLC16A7 SLC16A8

1.11e-076263M27355
PathwayWP_LACTATE_SHUTTLE_IN_GLIAL_CELLS

SLC16A3 SLC1A2 SLC16A7

1.57e-0613263M48056
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8

3.77e-06238266MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8

4.89e-06249266M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8 CFTR

1.75e-04681267MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8 CFTR

2.82e-04736267M27287
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC16A3 SLC16A7 SLC16A8

3.58e-0476263MM15072
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC16A3 SLC16A7 SLC16A8

4.81e-0484263M27334
PathwayREACTOME_BASIGIN_INTERACTIONS

SLC16A3 SLC16A8

8.81e-0424262MM17215
PathwayREACTOME_BASIGIN_INTERACTIONS

SLC16A3 SLC16A8

9.56e-0425262M4974
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC5A12 SLC36A4 SLC1A2

1.00e-03108263M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC5A12 SLC36A4 SLC1A2

1.03e-03109263MM15074
Pubmed

Cysteine 159 delineates a hinge region of the alternating access monocarboxylate transporter 1 and is targeted by cysteine-modifying inhibitors.

SLC16A3 SLC16A7 SLC16A8

7.77e-09533333999492
Pubmed

Genetic expression of monocarboxylate transporters during human and murine oocyte maturation and early embryonic development.

SLC16A3 SLC16A7 SLC16A8

7.77e-09533312056458
Pubmed

Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70).

SLC16A3 SLC16A7 SLC16A8

1.55e-08633315917240
Pubmed

The glucose-lactic acid cycle and gluconeogenesis.

SLC16A3 SLC16A7 SLC16A8

1.70e-07123337273846
Pubmed

The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond.

SLC16A3 SLC16A7 SLC16A8

2.81e-071433312739169
Pubmed

The role of monocarboxylate transporter 2 and 4 in the transport of gamma-hydroxybutyric acid in mammalian cells.

SLC16A3 SLC16A7

8.73e-07233217502341
Pubmed

Regulation of the glutamate transporter EAAT2 by PIKfyve.

PIKFYVE SLC1A2

8.73e-07233219910676
Pubmed

Basolateral sorting signals regulating tissue-specific polarity of heteromeric monocarboxylate transporters in epithelia.

SLC16A3 SLC16A8

8.73e-07233221199217
Pubmed

Neuronal and astroglial monocarboxylate transporters play key but distinct roles in hippocampus-dependent learning and memory formation.

SLC16A3 SLC16A7

8.73e-07233232693190
Pubmed

Cell-specific modulation of monocarboxylate transporter expression contributes to the metabolic reprograming taking place following cerebral ischemia.

SLC16A3 SLC16A7

8.73e-07233226751713
Pubmed

PIKfyve upregulates CFTR activity.

PIKFYVE CFTR

8.73e-07233219852935
Pubmed

Glucose affects monocarboxylate cotransporter (MCT) 1 expression during mouse preimplantation development.

SLC16A3 SLC16A8

2.62e-06333216514190
Pubmed

Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells.

SLC16A3 SLC16A8

5.23e-06433212657613
Pubmed

Characterization and regulation of monocarboxylate cotransporters Slc16a7 and Slc16a3 in preimplantation mouse embryos.

SLC16A3 SLC16A7

5.23e-06433218385447
Pubmed

Monocarboxylate transport in human corneal epithelium and cell lines.

SLC16A3 SLC16A7

5.23e-06433220035863
Pubmed

Astrocytic metabolic control of orexinergic activity in the lateral hypothalamus regulates sleep and wake architecture.

SLC16A3 SLC16A7

8.72e-06533239013907
Pubmed

Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas.

DOCK4 CSMD1

8.72e-06533219383911
Pubmed

Localization of members of MCT monocarboxylate transporter family Slc16 in the kidney and regulation during metabolic acidosis.

SLC5A12 SLC16A7

1.83e-05733220392797
Pubmed

Distribution of monocarboxylate transporters in the peripheral nervous system suggests putative roles in lactate shuttling and myelination.

SLC16A3 SLC16A7

2.44e-05833225762662
Pubmed

Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.

SLC16A3 SLC16A8

1.32e-041833231791063
Pubmed

MicroRNAs are essential for differentiation of the retinal pigmented epithelium and maturation of adjacent photoreceptors.

RPE65 SLC16A8

2.58e-042533226062936
Pubmed

Gse1, a component of the CoREST complex, is required for placenta development in the mouse.

SLC16A3 CPNE5

2.58e-042533237019373
Pubmed

Aberrant differentiation of second heart field mesoderm prefigures cellular defects in the outflow tract in response to loss of FGF8.

SLC16A3 CPNE5

2.80e-042633237060937
Pubmed

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.

CSMD1 CFTR

6.33e-043933224709693
GeneFamilySolute carriers

SLC5A12 SLC16A3 SLC36A4 SLC1A2 SLC16A7 SLC16A8

7.71e-06395236752
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALR3 CPNE5 SLC16A7 GOT1 DHRS7C

1.58e-07170335615cf9639c66b3fbd984ebe3f345280005d3c38a
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALR3 CPNE5 SLC16A7 GOT1 DHRS7C

1.58e-07170335d99f61aa85ea3f775165cb433421e6f1cda4f96b
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIKFYVE SLC16A3 SLC36A4 NAPRT

7.39e-061703348465c3069bbc08705d070927e712b6bc85ac7c5b
ToppCellStriatum-Macroglia-ASTROCYTE|Striatum / BrainAtlas - Mouse McCarroll V32

RPE65 SLC1A2 NAPRT

9.29e-051193330583387cc4497cf991fa42a81f2f66d9c6b774eb
ToppCellStriatum-Macroglia-ASTROCYTE-Gja1|Striatum / BrainAtlas - Mouse McCarroll V32

RPE65 SLC1A2 NAPRT

9.29e-05119333d47880ef1cff036192c43646a04fa8598dd7e1f4
ToppCellfacs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CALR3 DET1 CPNE5

1.70e-0414633326493014daa432db721613ef480d133f3da9eb58
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1|Striatum / BrainAtlas - Mouse McCarroll V32

HAS1 CPNE5 CFTR

1.70e-041463337b863f9bc63dc1afe015a18a70cd6ed0b71d1f09
ToppCellCerebellum-Macroglia-ASTROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

GABRG1 SLC1A2 NAPRT

1.88e-0415133371841d2001200d1595c85c2b007ee20791a72927
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1|Cerebellum / BrainAtlas - Mouse McCarroll V32

GABRG1 SLC1A2 NAPRT

1.88e-0415133360aced0c1cc6b509b73308d03d58a3c44d712ef4
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CSMD1 ST8SIA6 SLC16A8

2.31e-0416233380619a93c57fe16daf91dc571874ef9ac888953d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SLC5A12 HAS1 SLC16A8

2.61e-04169333b1611e61f635f8f9b87250e026ad30999cbee041
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-3_PAX6_NABP1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG1 ST8SIA6 RPE65

2.61e-041693333efaef30b4b1d0e79055f78aab1f230ec8d83450
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SLC5A12 HAS1 SLC16A8

2.61e-0416933329db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

VWA8 GOT1 CES2

2.71e-04171333c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A12 RPE65 SLC1A2

2.75e-04172333e15ab284df6dd241d4481f98864b18c39d757b8c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG1 PROKR2 OR52N5

2.85e-04174333e0de0a14319be1a115e5be05d6f9b562e7b32c4a
ToppCellfacs-Marrow-T-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF4 ST8SIA6 PROKR2

2.90e-041753330a01e0104cfa3091bc05b0f1d087c941688169a5
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG1 HAS1 SLC1A2

3.04e-041783336d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG1 HAS1 SLC1A2

3.04e-04178333d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCellfacs-Marrow-T-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF4 ST8SIA6 PROKR2

3.09e-041793333f2934c5f8816a7b7a6aef8d2f83ebf7b2b693bf
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VWA8 SLC16A7 GOT1

3.15e-041803339e09b3dfe344b5d50520711513d389865d73a861
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PIKFYVE BTN2A2 CPNE5

3.20e-041813330bc58c8942491e7ee5b858c5742770df7677532f
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF4 CSMD1 ST8SIA6

3.35e-041843331e54fd372c6e6a298f427b807c14cc49aaaffe80
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWA8 SLC16A7 GOT1

3.41e-0418533303f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCellMild_COVID-19-Epithelial-AT1/AT2|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

ST8SIA6 GOLT1A CFTR

3.41e-04185333c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWA8 SLC16A7 GOT1

3.46e-041863331850583d23903d08226aeb0edb3e07b0994330e4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWA8 SLC16A7 GOT1

3.46e-041863334dafc215c42e7949f932a3627359c107943b5d6b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ST8SIA6 SLC16A7 CFTR

3.46e-04186333a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF4 CSMD1 CPNE5

3.46e-041863337278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ST8SIA6 SLC16A7 CFTR

3.57e-04188333e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF4 SLC16A7 GOT1

3.57e-04188333d2d2b6c49448da24f457cedcd213f68841834a99
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF4 SLC16A7 GOT1

3.57e-04188333ab6fa1beff91584d9303c2a33735de89aae8d5cd
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 ST8SIA6 CPNE5

3.68e-041903331519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

CPNE5 VWA8 GOT1

3.68e-04190333fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellCOVID_vent-Lymphocytic-B_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

PIKFYVE BTN2A2 CPNE5

3.68e-0419033340b5e9e8f8fd8d84cb5b43e67b49267082348e9f
ToppCellCOVID_vent-Lymphocytic-B_cell-|COVID_vent / Disease condition, Lineage, Cell class and subclass

PIKFYVE BTN2A2 CPNE5

3.68e-04190333a37a32dc1b931562a6660074e19d5598efc65284
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PIKFYVE BTN2A2 CPNE5

3.74e-041913336a8b0987e75456a257954288206da0032605ff2a
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE5 GOT1 DHRS7C

3.74e-04191333715f5b449b8e075959c05a5b38389df319663164
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE5 GOT1 DHRS7C

3.74e-04191333c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF4 CSMD1 CPNE5

3.86e-04193333be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF4 CSMD1 CPNE5

3.86e-041933330c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QTNF4 CSMD1 CPNE5

3.86e-041933338689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellP28-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HAS1 CSMD1 SLC16A3

3.92e-041943333c661c6768c3f05d2aba03d329adb257ca201b2d
ToppCellP15-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HAS1 CSMD1 SLC16A3

3.92e-041943335f04d21c4e2d36e74b6c5889aa97fd98f75a0973
ToppCellIIH-mono3-|IIH / Condition, Cell_class and T cell subcluster

DOCK4 HAS1 SLC16A3

3.97e-0419533328a858b04a7b413916c07a8d880f5ea02e985461
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ST8SIA6 SLC16A3 SLC16A7

3.97e-041953331f07502597e9476345b07f9f25aeeb6c1de13013
ToppCellwk_20-22-Epithelial-Distal_epithelial-type_II_pneumocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GOLT1A SLC1A2 CFTR

3.97e-0419533345d1acd316d0ced97dfb150c3a943128d8fa4e7e
ToppCellIIH-mono3|IIH / Condition, Cell_class and T cell subcluster

DOCK4 HAS1 SLC16A3

3.97e-04195333c6dd5af582d257be64b718e30f60220c1bf1738a
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE5 GOT1 DHRS7C

4.03e-04196333fba52a4b82086dbae9a55038bf44c4539be926f5
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE5 GOT1 DHRS7C

4.03e-04196333a582130862bee76c0385156a333bfdfc75cf218b
ToppCell5'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.16e-041983338d629492d2199de8e036c19e9dacceb9c9e721a0
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.16e-04198333686d973483d027a3ffa2ad4430ba6e50f3d1378e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.16e-04198333a76366611f3561fc8aca7d62d1f0a0ea2bef7792
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.16e-04198333e67488695ce5e32ed8d149ed0b841540cbfdd3e2
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.16e-041983337696f042648bd53c0a019dfeea68808aa5898615
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.16e-04198333c48b3f026b16d48b8eca9f74dc1e3f3f39a89322
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.16e-041983336e6af8fad09f8e48b3f2ce463d5773b6a69864d1
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.22e-041993331e6ac65ce7133de4872dcd7e98e2a9e57d3d61b7
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.22e-04199333914f66e2b4af323d09fa2340a39cf8051d00a422
ToppCell5'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.22e-04199333a5fffe381be1ba7d192b68d1d3937ce47663658e
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.22e-0419933301c2721bc82cd672e9477029b4a7ecc77e2f1b00
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.22e-0419933338432e3ccbc546dc4c1dc2fb1d8d44f8a6de9424
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Unfolded_protein_responsible_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

SLC5A12 SLC16A3 GOLT1A

4.28e-0420033312078bc25be67180c0f4b37fef921cdcd1003576
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.28e-042003330ca955b71b97571b45e9e89004f1d0bb9fc9e67b
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.28e-042003333e13c9a4ba99a7dfbf738b0fb63fb54b4dee5897
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC5A12 GOLT1A CES2

4.28e-0420033373bfdf068a8ecbefc1e6afe9686df73658ee042f
ComputationalGenes in the cancer module 218.

SLC16A3 SLC16A7 SLC16A8

2.47e-0620153MODULE_218
ComputationalGenes in the cancer module 186.

SLC16A3 SLC16A8

3.40e-0420152MODULE_186
ComputationalGenes in the cancer module 71.

SLC16A3 SLC16A8

4.13e-0422152MODULE_71
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

SLC5A12 CES2

2.14e-0350152GAVISH_3CA_MALIGNANT_METAPROGRAM_38_GLUTATHIONE
DrugPyruvic acid

SLC16A3 SLC16A7 SLC16A8

9.99e-0714333DB00119
Drug2-cyano-3-phenylacrylic acid

SLC5A12 SLC16A3 SLC16A7

6.24e-0625333CID000070534
Drugalpha-cyano-4-hydroxycinnamate

SLC5A12 SLC16A3 SLC16A7

1.47e-0533333CID000002102
Drugbenzoate

SLC5A12 SLC16A3 SLC16A7 CFTR CES2

1.57e-05221335CID000000242
DrugAC1NEL3G

HAS1 CFTR

2.03e-055332CID000360405
Drugferric sulfate

RPE65 GOT1

2.03e-055332ctd:C024823
Diseaseperipheral arterial disease, traffic air pollution measurement

SLC16A3 GOLT1A VWA8 GOT1

5.64e-05194324EFO_0004265, EFO_0007908
Diseasecentral nervous system cancer, glioblastoma multiforme

RHBDF1 SLC16A8

1.03e-0414322EFO_0000326, EFO_0000519
Diseaseresponse to radiation, hearing loss, response to antineoplastic agent

GOLT1A GOT1

1.14e-0346322EFO_0004238, GO_0009314, GO_0097327
Diseasepost-traumatic stress disorder

DOCK4 BTN2A2 CSMD1

1.35e-03202323EFO_0001358
Diseasehealth literacy measurement

CSMD1 SLC1A2

1.52e-0353322EFO_0010104
DiseaseBipolar Disorder

GABRG1 CSMD1 PROKR2 SLC1A2

1.69e-03477324C0005586

Protein segments in the cluster

PeptideGeneStartEntry
FFSGFFVVFLSVLPY

CFTR

311

P13569
TVPKEFVVFGQFAYF

CSMD1

1656

Q96PZ7
NGRFYAISARFKPFS

CALR3

71

Q96L12
GQFRCRVPGAYFFSF

C1QTNF4

66

Q9BXJ3
RVPGAYFFSFTAGKA

C1QTNF4

71

Q9BXJ3
FLRKFSPDGRYFIAF

DET1

61

Q7L5Y6
FAYGFPKAVSVFFRA

SLC16A8

31

O95907
KYLFNFRGVAASFRF

POGLUT1

266

Q8NBL1
FGCFVITGFSYAFPK

SLC16A3

26

O15427
FYSLRFFGNFTPKKD

LMBR1

366

Q8WVP7
FYVVAESFKFVRLFP

EIF2B1

226

Q14232
LPFVFRSFFGGNYIK

CES2

461

O00748
AFISIGFSYAFPKAV

SLC16A7

26

O60669
GFSYAFPKAVTVFFK

SLC16A7

31

O60669
TYGFFSLFKGFFPVA

GOLT1A

91

Q6ZVE7
PFKSAYSSFVNLFRF

PIKFYVE

41

Q9Y2I7
KRTFFVEYHFPVGFS

C2CD3

576

Q4AC94
FFRVGFYGKKFPFFL

DOCK4

1316

Q8N1I0
SYSRIFFPTAFALFN

GABRG1

441

Q8N1C3
YFVVTRKNPFSFFAG

SLC1A2

336

P43004
RFLFPFFDSAYQGFA

GOT1

216

P17174
FPFFVAATVLRLFYA

HAS1

411

Q92839
KAAVYVRTFFPEFFF

DHRS7C

281

A6NNS2
FRSQFSPAVFVYKGG

BTN2A2

71

Q8WVV5
KDFFGKSDPFLVFYR

CPNE5

191

Q9HCH3
YVPAFFTFFAHRFGG

OR52N5

261

Q8NH56
PCKNIFSRFFSYFRG

RPE65

111

Q16518
FLSFAFLPYISFGKF

RHBDF1

781

Q96CC6
YGDAFFLLPAFSFRA

ST8SIA6

261

P61647
AFVAYALAFPRAFQG

NAPRT

271

Q6XQN6
FYGFTIVRDFFPTVF

PROKR2

291

Q8NFJ6
FPGAFSKAFFFPSFN

PIGO

186

Q8TEQ8
PSEVYRFGASFLVFF

SLC5A12

71

Q1EHB4
KSGFFVDFFDIFPRT

VWA8

1146

A3KMH1
KKYPLFFGTAVFAFE

SLC36A4

271

Q6YBV0