Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionchannel activity

ANO4 RHCG SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 RHAG RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A ANO7 CACNA1G CNGA4

7.93e-0952514419GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

ANO4 RHCG SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 RHAG RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A ANO7 CACNA1G CNGA4

8.18e-0952614419GO:0022803
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ANO4 RHCG SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 NDUFS2 RHAG RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A ANO7 CACNA1G ATP2A1 CNGA4

1.22e-0775814421GO:0015318
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

RHCG SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 NDUFS2 RHAG RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A CACNA1G ATP2A1 CNGA4

1.32e-0762714419GO:0022890
GeneOntologyMolecularFunctiongated channel activity

ANO4 CACNA1B CACNA1F CACNA1S KCNV2 RYR2 ITPR1 KCNA3 KCNA5 KCNQ4 SCN7A ANO7 CACNA1G CNGA4

1.42e-0733414414GO:0022836
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A CACNA1G ATP2A1 CNGA4

2.59e-0746514416GO:0046873
GeneOntologyMolecularFunctionmonoatomic ion channel activity

ANO4 CACNA1B CACNA1F CACNA1S KCNV2 RYR2 ITPR1 KCNA3 KCNA5 NALCN KCNQ4 SCN7A ANO7 CACNA1G CNGA4

1.20e-0645914415GO:0005216
GeneOntologyMolecularFunctionammonium channel activity

RHCG SLC12A6 RHAG SLC12A4

1.23e-06121444GO:0008519
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1B CACNA1F CACNA1S KCNV2 RYR2 ITPR1 KCNA3 KCNA5 NALCN KCNQ4 SCN7A CACNA1G CNGA4

1.26e-0634314413GO:0005261
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1B CACNA1F CACNA1S CACNA1G

2.45e-06141444GO:0008331
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ANO4 SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 NDUFS2 RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A ANO7 CACNA1G ATP2A1 CNGA4

4.40e-0679314419GO:0015075
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 NDUFS2 RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A CACNA1G ATP2A1 CNGA4

6.17e-0666414417GO:0008324
GeneOntologyMolecularFunctiontransmembrane transporter activity

ANO4 RHCG SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 NDUFS2 RHAG RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 ABCB9 NALCN KCNQ4 SCN7A ABCB11 ANO7 CACNA1G ATP2A1 CNGA4

1.23e-05118014423GO:0022857
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G ATP2A1 CNGA4

1.40e-051511448GO:0015085
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1B CACNA1F CACNA1S KCNV2 KCNA3 KCNA5 KCNQ4 CACNA1G

1.47e-051521448GO:0022843
GeneOntologyMolecularFunctioncalcium ion binding

UNC13B CACNA1B TBC1D9B CDHR3 PCLO ADGRV1 CUBN RYR2 ITPR1 GLCE UNC13C TNNC2 PLCG1 CABCOCO1 ATP2A1 CDH10 UNC13A

2.91e-0574914417GO:0005509
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G CNGA4

4.21e-051291447GO:0005262
GeneOntologyMolecularFunctiontransporter activity

ANO4 RHCG SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 NDUFS2 RHAG RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 ABCB9 NALCN KCNQ4 SCN7A ABCB11 ANO7 CACNA1G ATP2A1 CNGA4

4.93e-05128914423GO:0005215
GeneOntologyMolecularFunctionphorbol ester receptor activity

UNC13B UNC13C

5.16e-0521442GO:0001565
GeneOntologyMolecularFunctionnon-kinase phorbol ester receptor activity

UNC13B UNC13C

5.16e-0521442GO:0001566
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1B CACNA1F CACNA1S KCNV2 KCNA3 KCNA5 KCNQ4 CACNA1G

5.35e-051821448GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1B CACNA1F CACNA1S KCNV2 KCNA3 KCNA5 KCNQ4 CACNA1G

5.78e-051841448GO:0022832
GeneOntologyMolecularFunctionATP hydrolysis activity

HSP90AB4P TRAP1 ABCB9 SUPV3L1 DDX54 ABCB11 DDX3Y KIF5B KIF5C ATP2A1 DHX29 RAD17

8.68e-0544114412GO:0016887
GeneOntologyMolecularFunctionproteoglycan sulfotransferase activity

GAL3ST4 GAL3ST3

1.54e-0431442GO:0050698
GeneOntologyMolecularFunctiondiacylglycerol binding

UNC13B UNC13C UNC13A

1.92e-04161443GO:0019992
GeneOntologyMolecularFunctiongalactose 3-O-sulfotransferase activity

GAL3ST4 GAL3ST3

3.07e-0441442GO:0050694
GeneOntologyMolecularFunctioncarbon dioxide transmembrane transporter activity

RHCG RHAG

3.07e-0441442GO:0035379
GeneOntologyMolecularFunctionmyosin light chain kinase activity

MYLK2 MYLK3

3.07e-0441442GO:0004687
GeneOntologyMolecularFunctiongalactosylceramide sulfotransferase activity

GAL3ST4 GAL3ST3

3.07e-0441442GO:0001733
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1B CACNA1F CACNA1S CACNA1G

3.35e-04461444GO:0005245
GeneOntologyMolecularFunctionGABA receptor binding

PLCL2 PLCL1 TRAK2

3.83e-04201443GO:0050811
GeneOntologyMolecularFunctionsyntaxin-1 binding

UNC13B UNC13C UNC13A

6.65e-04241443GO:0017075
GeneOntologyMolecularFunctionphosphatidylinositol phospholipase C activity

PLCL2 PLCL1 PLCG1

8.46e-04261443GO:0004435
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

NALCN SCN7A CACNA1G

8.46e-04261443GO:0005248
GeneOntologyMolecularFunctionGTPase activator activity

DOCK3 ARL2BP TBC1D9B EVI5 ARFGAP2 IQGAP3 USP6NL EVI5L

9.62e-042791448GO:0005096
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK3 ARL2BP TBC1D9B RAPGEF4 EVI5 ARFGAP2 KIAA1755 PLCG1 IQGAP3 USP6NL EVI5L

1.14e-0350714411GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK3 ARL2BP TBC1D9B RAPGEF4 EVI5 ARFGAP2 KIAA1755 PLCG1 IQGAP3 USP6NL EVI5L

1.14e-0350714411GO:0030695
GeneOntologyMolecularFunctionphospholipase C activity

PLCL2 PLCL1 PLCG1

1.17e-03291443GO:0004629
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC12A6 KCNV2 KCNA3 KCNA5 SLC12A4 KCNQ4

1.35e-031671446GO:0015079
GeneOntologyMolecularFunctionmyosin light chain binding

MYLK2 IQGAP3

1.41e-0381442GO:0032027
GeneOntologyMolecularFunctioncalmodulin binding

UNC13B CACNA1S RYR2 MYLK2 UNC13C IQGAP3 UNC13A

1.42e-032301447GO:0005516
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

HSP90AB4P ATL1 TRAP1 RAB34 ABCB9 SUPV3L1 DDX54 ABCB11 DDX3Y KIF5B KIF5C ATP2A1 DHX29 RAD17

1.46e-0377514414GO:0017111
GeneOntologyMolecularFunctionATP-dependent activity

HSP90AB4P TRAP1 ABCB9 SUPV3L1 DDX54 ABCB11 DDX3Y KIF5B KIF5C ATP2A1 DHX29 RAD17

1.67e-0361414412GO:0140657
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR2 ITPR1 CNGA4

1.71e-03331443GO:0005217
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A6 SLC12A4

1.80e-0391442GO:0015379
GeneOntologyMolecularFunctionsmall GTPase binding

UNC13B DOCK3 RAPGEF4 EVI5 RAB34 IQGAP3 USP6NL EVI5L

2.33e-033211448GO:0031267
GeneOntologyMolecularFunctionRNA helicase activity

SUPV3L1 DDX54 DDX3Y DHX29

2.45e-03781444GO:0003724
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

SUPV3L1 DDX54 DDX3Y DHX29

2.68e-03801444GO:0008186
GeneOntologyMolecularFunctionpyrophosphatase activity

HSP90AB4P ATL1 TRAP1 RAB34 ABCB9 SUPV3L1 DDX54 ABCB11 DDX3Y KIF5B KIF5C ATP2A1 DHX29 RAD17

3.02e-0383914414GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

HSP90AB4P ATL1 TRAP1 RAB34 ABCB9 SUPV3L1 DDX54 ABCB11 DDX3Y KIF5B KIF5C ATP2A1 DHX29 RAD17

3.05e-0384014414GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

HSP90AB4P ATL1 TRAP1 RAB34 ABCB9 SUPV3L1 DDX54 ABCB11 DDX3Y KIF5B KIF5C ATP2A1 DHX29 RAD17

3.05e-0384014414GO:0016818
GeneOntologyMolecularFunctionmyosin binding

ADGRV1 MYLK2 TRAK2 IQGAP3

3.34e-03851444GO:0017022
GeneOntologyMolecularFunction3'-phosphoadenosine 5'-phosphosulfate binding

GAL3ST4 GAL3ST3

3.82e-03131442GO:0050656
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

ITPR1 PLCL2

4.44e-03141442GO:0070679
GeneOntologyMolecularFunctionscaffold protein binding

RYR2 GRK2 KCNA5 CACNA1G

4.61e-03931444GO:0097110
GeneOntologyMolecularFunctionGTPase binding

UNC13B DOCK3 RAPGEF4 EVI5 RAB34 IQGAP3 USP6NL EVI5L

4.66e-033601448GO:0051020
GeneOntologyBiologicalProcessestablishment of vesicle localization

UNC13B CUL3 PCLO AP1M2 MYLK2 ARFGAP2 MAPK15 UNC13C KIF5B KIF5C TRAK2 UNC13A

6.36e-0822414512GO:0051650
GeneOntologyBiologicalProcessvesicle localization

UNC13B CUL3 PCLO AP1M2 MYLK2 ARFGAP2 MAPK15 UNC13C KIF5B KIF5C TRAK2 UNC13A

1.84e-0724714512GO:0051648
GeneOntologyBiologicalProcessdense core granule priming

UNC13B UNC13C UNC13A

1.35e-0641453GO:0061789
GeneOntologyBiologicalProcessammonium transmembrane transport

RHCG SLC12A6 RHAG SLC12A4

1.59e-06131454GO:0072488
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

UNC13B CACNA1B PCLO RAPGEF4 BACE1 MYLK2 NTNG2 GRK2 NALCN KCNQ4 PLCL2 UNC13C PLCL1 PLCG1 KIF5B FBXO45 UNC13A

4.35e-0666314517GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

UNC13B CACNA1B PCLO RAPGEF4 BACE1 MYLK2 NTNG2 GRK2 NALCN KCNQ4 PLCL2 UNC13C PLCL1 PLCG1 KIF5B FBXO45 UNC13A

4.44e-0666414517GO:0099177
GeneOntologyBiologicalProcesssynaptic signaling

UNC13B SLC12A6 CACNA1B PCLO RAPGEF4 BACE1 MYLK2 ITPR1 NTNG2 GRK2 SLC12A4 NALCN KCNQ4 PLCL2 UNC13C CACNA1G PLCL1 PLCG1 KIF5B FBXO45 UNC13A

4.78e-0697614521GO:0099536
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

UNC13B SLC12A6 CACNA1B PCLO RAPGEF4 BACE1 MYLK2 NTNG2 GRK2 SLC12A4 NALCN KCNQ4 PLCL2 UNC13C CACNA1G PLCL1 PLCG1 KIF5B FBXO45 UNC13A

8.43e-0693114520GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

UNC13B SLC12A6 CACNA1B PCLO RAPGEF4 BACE1 MYLK2 NTNG2 GRK2 SLC12A4 NALCN KCNQ4 PLCL2 UNC13C CACNA1G PLCL1 PLCG1 KIF5B FBXO45 UNC13A

8.43e-0693114520GO:0007268
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

ANO4 RHCG SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 RHAG RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A ANO7 CACNA1G PLCG1 ATP2A1 CNGA4

8.96e-06101714521GO:0098660
GeneOntologyBiologicalProcesstrans-synaptic signaling

UNC13B SLC12A6 CACNA1B PCLO RAPGEF4 BACE1 MYLK2 NTNG2 GRK2 SLC12A4 NALCN KCNQ4 PLCL2 UNC13C CACNA1G PLCL1 PLCG1 KIF5B FBXO45 UNC13A

9.55e-0693914520GO:0099537
GeneOntologyBiologicalProcessresponse to caffeine

CACNA1S CAD RYR2 HDAC2

1.28e-05211454GO:0031000
GeneOntologyBiologicalProcessstriated muscle contraction

CACNA1S RYR2 MYLK2 GRK2 KCNA5 SCN7A CACNA1G TNNC2 ATP2A1

2.35e-052171459GO:0006941
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

RHCG SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 RHAG RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A CACNA1G PLCG1 ATP2A1 CNGA4

2.57e-0592214519GO:0098662
GeneOntologyBiologicalProcessactin-mediated cell contraction

EPB41L5 RYR2 MYLK2 KCNA5 SCN7A CACNA1G ATP2A1

3.25e-051271457GO:0070252
GeneOntologyBiologicalProcessorganelle localization

UNC13B CUL3 PCLO AP1M2 MYLK2 ARFGAP2 MAPK15 RAB34 FHOD1 MTM1 UNC13C KIF5B KIF5C TRAK2 ATP2A1 UNC13A

3.64e-0570314516GO:0051640
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell signaling

RYR2 KCNA5 CACNA1G

3.94e-05101453GO:0086018
GeneOntologyBiologicalProcessSA node cell action potential

RYR2 KCNA5 CACNA1G

3.94e-05101453GO:0086015
GeneOntologyBiologicalProcesspresynaptic dense core vesicle exocytosis

UNC13B UNC13C UNC13A

3.94e-05101453GO:0099525
GeneOntologyBiologicalProcessdense core granule localization

UNC13B UNC13C KIF5B UNC13A

4.21e-05281454GO:0032253
GeneOntologyBiologicalProcessdense core granule docking

UNC13B UNC13A

4.91e-0521452GO:0061790
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell communication

RYR2 KCNA5 CACNA1G

5.39e-05111453GO:0086070
GeneOntologyBiologicalProcesspositive regulation of secretion

UNC13B CACNA1B NPR3 RAPGEF4 ITPR1 TARDBP GRK2 RAB34 ABCB11 CACNA1G KIF5B UNC13A

6.00e-0543514512GO:0051047
GeneOntologyBiologicalProcessregulation of system process

UNC13B CACNA1B CACNA1S NPR3 PCLO RAPGEF4 GTF2IRD1 PTGS1 RYR2 MYLK2 GRK2 KCNA5 WDR35 CACNA1G TNNC2 ATP2A1

6.07e-0573414516GO:0044057
GeneOntologyBiologicalProcessanterograde dendritic transport

KIF5B KIF5C TRAK2

7.15e-05121453GO:0098937
GeneOntologyBiologicalProcessneuronal dense core vesicle exocytosis

UNC13B UNC13C UNC13A

7.15e-05121453GO:0099011
GeneOntologyBiologicalProcesssecretory granule localization

UNC13B UNC13C KIF5B UNC13A

9.22e-05341454GO:0032252
GeneOntologyBiologicalProcessactin filament-based movement

EPB41L5 RYR2 MYLK2 KCNA5 SCN7A CACNA1G ATP2A1

1.06e-041531457GO:0030048
GeneOntologyBiologicalProcessmusculoskeletal movement

XRCC1 MYLK2 ITPR1 TNNC2 ATP2A1

1.25e-04691455GO:0050881
GeneOntologyBiologicalProcessestablishment of organelle localization

UNC13B CUL3 PCLO AP1M2 MYLK2 ARFGAP2 MAPK15 FHOD1 UNC13C KIF5B KIF5C TRAK2 UNC13A

1.30e-0454614513GO:0051656
GeneOntologyBiologicalProcessmuscle system process

CACNA1S GTF2IRD1 PTGS1 RYR2 MYLK2 GRK2 KCNA5 SCN7A CACNA1G KDM4A TNNC2 ATP2A1 HDAC2

1.32e-0454714513GO:0003012
GeneOntologyBiologicalProcesspotassium ion transport

SLC12A6 KCNV2 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 KIF5B CNGA4

1.34e-042721459GO:0006813
GeneOntologyBiologicalProcessvesicle targeting

CUL3 PCLO AP1M2 ARFGAP2 MAPK15

1.44e-04711455GO:0006903
GeneOntologyBiologicalProcessdense core granule exocytosis

UNC13B UNC13C UNC13A

1.46e-04151453GO:1990504
GeneOntologyBiologicalProcesspositive regulation of fast-twitch skeletal muscle fiber contraction

MYLK2 ATP2A1

1.47e-0431452GO:0031448
GeneOntologyBiologicalProcessregulation of fast-twitch skeletal muscle fiber contraction

MYLK2 ATP2A1

1.47e-0431452GO:0031446
GeneOntologyBiologicalProcessmulticellular organismal movement

XRCC1 MYLK2 ITPR1 TNNC2 ATP2A1

1.64e-04731455GO:0050879
GeneOntologyBiologicalProcessregulation of secretion

UNC13B CACNA1B NPR3 PCLO RAPGEF4 PTGS1 ITPR1 TARDBP GRK2 KCNA5 RAB34 ABCB11 CACNA1G KIF5B FBXO45 UNC13A

1.67e-0480114516GO:0051046
GeneOntologyBiologicalProcesscardiac muscle contraction

RYR2 MYLK2 GRK2 KCNA5 SCN7A CACNA1G ATP2A1

1.82e-041671457GO:0060048
GeneOntologyBiologicalProcesssynaptic vesicle docking

UNC13B UNC13C UNC13A

2.15e-04171453GO:0016081
GeneOntologyBiologicalProcessmetal ion transport

SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A CACNA1G PLCG1 KIF5B ATP2A1 CNGA4

2.34e-04100014518GO:0030001
GeneOntologyBiologicalProcesssynaptic vesicle exocytosis

UNC13B CACNA1B PCLO UNC13C FBXO45 UNC13A

2.57e-041251456GO:0016079
GeneOntologyBiologicalProcessregulation of synaptic transmission, GABAergic

NALCN PLCL2 PLCL1 KIF5B

2.79e-04451454GO:0032228
GeneOntologyBiologicalProcesscalcium-ion regulated exocytosis

UNC13B RAPGEF4 UNC13C CACNA1G UNC13A

2.83e-04821455GO:0017156
GeneOntologyBiologicalProcesscalcium activated phosphatidylserine scrambling

ANO4 ANO7

2.92e-0441452GO:0061589
GeneOntologyBiologicalProcesscarbon dioxide transmembrane transport

RHCG RHAG

2.92e-0441452GO:0035378
GeneOntologyBiologicalProcessammonium import across plasma membrane

SLC12A6 SLC12A4

2.92e-0441452GO:0140157
GeneOntologyBiologicalProcessfast-twitch skeletal muscle fiber contraction

MYLK2 ATP2A1

2.92e-0441452GO:0031443
GeneOntologyBiologicalProcessdendritic transport

KIF5B KIF5C TRAK2

3.04e-04191453GO:0098935
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ANO4 SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A ANO7 CACNA1G PLCG1 ATP2A1 CNGA4

3.10e-04111514519GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A CACNA1G PLCG1 ATP2A1 CNGA4

3.41e-0494214517GO:0098655
GeneOntologyBiologicalProcesssecretion

UNC13B CACNA1B DDR1 NPR3 CAD PCLO RAPGEF4 AP1M2 PTGS1 ITPR1 TARDBP GRK2 KCNA5 RAB34 ABCB11 UNC13C CACNA1G KIF5B FBXO45 UNC13A

3.55e-04122114520GO:0046903
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1B CACNA1F CACNA1S CACNA1G

3.59e-04481454GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1B CACNA1F CACNA1S CACNA1G

3.59e-04481454GO:1902656
GeneOntologyBiologicalProcessinorganic ion homeostasis

RHCG SLC12A6 CACNA1F CACNA1S ACO1 RHAG RYR2 ITPR1 KCNA5 SLC12A4 SCN7A PLCG1 ATP2A1

4.57e-0462214513GO:0098771
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 NALCN CACNA1G PLCG1 ATP2A1 CNGA4

4.65e-0439214510GO:0070588
GeneOntologyBiologicalProcesschemical homeostasis

UNC13B RHCG SLC12A6 CACNA1F CACNA1S ACACA ACO1 TM6SF2 RHAG RYR2 ITPR1 GRK2 KCNA5 RAB34 SLC12A4 SCN7A ABCB11 PLCG1 KIF5B ATP2A1

4.75e-04124914520GO:0048878
GeneOntologyBiologicalProcesscalcium activated phospholipid scrambling

ANO4 ANO7

4.84e-0451452GO:0061588
GeneOntologyBiologicalProcesscalcium activated phosphatidylcholine scrambling

ANO4 ANO7

4.84e-0451452GO:0061590
GeneOntologyBiologicalProcesscalcium activated galactosylceramide scrambling

ANO4 ANO7

4.84e-0451452GO:0061591
GeneOntologyBiologicalProcessregulation of twitch skeletal muscle contraction

MYLK2 ATP2A1

4.84e-0451452GO:0014724
GeneOntologyBiologicalProcessmaintenance of location in cell

CACNA1S ARL2BP RYR2 ITPR1 VPS13D GRK2 PLCG1 ATP2A1

5.03e-042591458GO:0051651
GeneOntologyBiologicalProcesscardiac muscle cell contraction

RYR2 KCNA5 SCN7A CACNA1G ATP2A1

5.07e-04931455GO:0086003
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

SLC12A6 CACNA1B CACNA1F CACNA1S SLC12A4 CACNA1G

5.08e-041421456GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

SLC12A6 CACNA1B CACNA1F CACNA1S SLC12A4 CACNA1G

5.08e-041421456GO:0098659
GeneOntologyBiologicalProcesscellular homeostasis

UNC13B RHCG SLC12A6 CACNA1F CACNA1S ACO1 RHAG RYR2 ITPR1 GRK2 RAB34 SLC12A4 MTM1 SCN7A PLCG1 KIF5B ATP2A1

5.42e-0498114517GO:0019725
GeneOntologyBiologicalProcessmuscle contraction

CACNA1S PTGS1 RYR2 MYLK2 GRK2 KCNA5 SCN7A CACNA1G TNNC2 ATP2A1

5.44e-0440014510GO:0006936
GeneOntologyBiologicalProcessaction potential

KCNV2 RAPGEF4 RYR2 KCNA3 KCNA5 SCN7A CACNA1G

5.59e-042011457GO:0001508
GeneOntologyBiologicalProcesssynaptic vesicle cycle

UNC13B CACNA1B PCLO RAPGEF4 AP2S1 UNC13C FBXO45 UNC13A

5.71e-042641458GO:0099504
GeneOntologyBiologicalProcessregulation of muscle contraction

CACNA1S PTGS1 RYR2 MYLK2 GRK2 TNNC2 ATP2A1

5.76e-042021457GO:0006937
GeneOntologyBiologicalProcesspositive regulation of secretion by cell

UNC13B CACNA1B RAPGEF4 ITPR1 TARDBP GRK2 RAB34 CACNA1G KIF5B UNC13A

5.87e-0440414510GO:1903532
GeneOntologyBiologicalProcessregulation of membrane potential

UNC13B KCNV2 PCLO RAPGEF4 RYR2 KCNA3 GRK2 KCNA5 NALCN SCN7A CACNA1G KIF5B

6.01e-0455914512GO:0042391
GeneOntologyBiologicalProcesscalcium ion import

CACNA1B CACNA1F CACNA1S CACNA1G ATP2A1

6.44e-04981455GO:0070509
GeneOntologyBiologicalProcesscalcium ion-regulated exocytosis of neurotransmitter

UNC13B UNC13C UNC13A

6.99e-04251453GO:0048791
GeneOntologyBiologicalProcesspositive regulation of RNA binding

NCBP1 EIF4G1

7.23e-0461452GO:1905216
GeneOntologyBiologicalProcesspositive regulation of ATPase-coupled calcium transmembrane transporter activity

RYR2 ATP2A1

7.23e-0461452GO:1901896
GeneOntologyBiologicalProcessnegative regulation of synaptic plasticity

UNC13B UNC13C

7.23e-0461452GO:0031914
GeneOntologyBiologicalProcessammonium homeostasis

RHCG RHAG

7.23e-0461452GO:0097272
GeneOntologyBiologicalProcessregulation of secretion by cell

UNC13B CACNA1B PCLO RAPGEF4 PTGS1 ITPR1 TARDBP GRK2 KCNA5 RAB34 CACNA1G KIF5B FBXO45 UNC13A

7.39e-0474014514GO:1903530
GeneOntologyBiologicalProcesspositive regulation of muscle contraction

CACNA1S PTGS1 MYLK2 ATP2A1

7.90e-04591454GO:0045933
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G PLCG1

8.77e-042171457GO:0097553
GeneOntologyBiologicalProcessmitochondrion distribution

MTM1 KIF5B TRAK2

8.80e-04271453GO:0048311
GeneOntologyBiologicalProcessresponse to amyloid-beta

CACNA1B BACE1 MMP3 HDAC2

8.96e-04611454GO:1904645
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

RYR2 KCNA5 SCN7A CACNA1G

9.53e-04621454GO:0086002
GeneOntologyBiologicalProcessexocytic process

UNC13B CACNA1B PCLO UNC13C UNC13A

9.58e-041071455GO:0140029
GeneOntologyBiologicalProcessregulation of cilium assembly

TBC1D9B EVI5 MAPK15 USP6NL EVI5L

9.99e-041081455GO:1902017
GeneOntologyBiologicalProcesstwitch skeletal muscle contraction

MYLK2 ATP2A1

1.01e-0371452GO:0014721
GeneOntologyBiologicalProcessanterograde dendritic transport of neurotransmitter receptor complex

KIF5B KIF5C

1.01e-0371452GO:0098971
GeneOntologyBiologicalProcessvoluntary skeletal muscle contraction

MYLK2 ATP2A1

1.01e-0371452GO:0003010
GeneOntologyBiologicalProcesscap-dependent translational initiation

NCBP1 EIF4G1

1.01e-0371452GO:0002191
GeneOntologyBiologicalProcessmitochondrion localization

MTM1 KIF5B TRAK2 ATP2A1

1.01e-03631454GO:0051646
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D9B EVI5 PIP5K1A USP6NL EVI5L

1.04e-031091455GO:0090630
GeneOntologyBiologicalProcessprotein homooligomerization

ACACA KCNV2 ME1 ATL1 ITPR1 KCNA3 KCNA5

1.06e-032241457GO:0051260
GeneOntologyBiologicalProcessregulated exocytosis

UNC13B CACNA1B PCLO RAPGEF4 UNC13C CACNA1G FBXO45 UNC13A

1.07e-032911458GO:0045055
GeneOntologyBiologicalProcessintracellular chemical homeostasis

UNC13B RHCG SLC12A6 CACNA1F CACNA1S ACO1 RHAG RYR2 ITPR1 GRK2 RAB34 SCN7A PLCG1 KIF5B ATP2A1

1.17e-0386614515GO:0055082
GeneOntologyBiologicalProcessheart contraction

CACNA1B RYR2 MYLK2 GRK2 KCNA5 SCN7A CACNA1G ATP2A1

1.25e-032981458GO:0060047
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC12A6 CACNA1B CACNA1F CACNA1S KCNV2 RYR2 ITPR1 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4 SCN7A CACNA1G PLCG1 KIF5B ATP2A1 CNGA4

1.28e-03115714518GO:0006812
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

SLC12A6 KCNV2 KCNA3 KCNA5 SLC12A4 NALCN KCNQ4

1.29e-032321457GO:0071805
GeneOntologyBiologicalProcesssynaptic vesicle priming

UNC13B UNC13C UNC13A

1.32e-03311453GO:0016082
GeneOntologyBiologicalProcessregulation of RNA binding

NCBP1 EIF4G1

1.34e-0381452GO:1905214
GeneOntologyCellularComponentcation channel complex

CACNA1B CACNA1F CACNA1S KCNV2 RYR2 KCNA3 KCNA5 KCNQ4 SCN7A CACNA1G ATP2A1 CNGA4

9.31e-0823514512GO:0034703
GeneOntologyCellularComponentaxon terminus

UNC13B CACNA1B CAD CDHR3 PCLO RAPGEF4 MYLK2 KCNA3 UNC13C UNC13A

2.14e-0621014510GO:0043679
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1B CACNA1F CACNA1S KCNV2 RYR2 KCNA3 KCNA5 NALCN KCNQ4 SCN7A CACNA1G ATP2A1 CNGA4

2.42e-0637814513GO:0034702
GeneOntologyCellularComponentneuron projection terminus

UNC13B CACNA1B CAD CDHR3 PCLO RAPGEF4 MYLK2 KCNA3 UNC13C UNC13A

5.41e-0623314510GO:0044306
GeneOntologyCellularComponentcytoplasmic region

UNC13B RSPH4A PCLO TULP3 MAPK15 WDR35 UNC13C KIF5B KIF5C TRAK2 UNC13A RSPH10B

8.23e-0636014512GO:0099568
GeneOntologyCellularComponentdistal axon

UNC13B CACNA1B CAD CDHR3 PCLO RAPGEF4 MYLK2 KCNA3 UNC13C KIF5B KIF5C TRAK2 UNC13A

1.10e-0543514513GO:0150034
GeneOntologyCellularComponentcalcium channel complex

CACNA1B CACNA1F CACNA1S RYR2 CACNA1G ATP2A1

1.17e-05731456GO:0034704
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1B CACNA1F CACNA1S KCNV2 NDUFS2 RYR2 KCNA3 KCNA5 NALCN KCNQ4 SCN7A CACNA1G ATP2A1 CNGA4

1.72e-0552314514GO:1902495
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

UNC13B PCLO UNC13C UNC13A

1.77e-05231454GO:0098831
GeneOntologyCellularComponenttransporter complex

CACNA1B CACNA1F CACNA1S KCNV2 NDUFS2 RYR2 KCNA3 KCNA5 NALCN KCNQ4 SCN7A CACNA1G ATP2A1 CNGA4

3.00e-0555014514GO:1990351
GeneOntologyCellularComponentaxon

UNC13B SLC12A6 CACNA1B CAD CDHR3 PCLO RAPGEF4 BACE1 ATL1 MYLK2 NTNG2 KCNA3 GRK2 UNC13C KIF5B KIF5C TRAK2 UNC13A

4.64e-0589114518GO:0030424
GeneOntologyCellularComponentcilium

CUL3 CACNA1F ARL2BP RSPH4A RAPGEF4 ADGRV1 PTGS1 TULP3 RSPH10B2 MAPK15 GRK2 RAB34 WDR35 KIF5B KIF5C CABCOCO1 CNGA4 RSPH10B

5.14e-0589814518GO:0005929
GeneOntologyCellularComponentterminal bouton

UNC13B CAD PCLO MYLK2 UNC13C UNC13A

5.57e-05961456GO:0043195
GeneOntologyCellularComponentpresynaptic active zone

UNC13B CACNA1B PCLO NTNG2 UNC13C CDH10 UNC13A

5.82e-051411457GO:0048786
GeneOntologyCellularComponentcalyx of Held

UNC13B KCNA3 UNC13C UNC13A

1.10e-04361454GO:0044305
GeneOntologyCellularComponentpresynapse

UNC13B CACNA1B CAD CDHR3 PCLO RAPGEF4 BACE1 MYLK2 ITPR1 NTNG2 AP2S1 KCNA3 GRK2 UNC13C FBXO45 CDH10 UNC13A

1.42e-0488614517GO:0098793
GeneOntologyCellularComponentsarcoplasm

CACNA1S H6PD RYR2 ITPR1 IFRD1 ATP2A1

1.45e-041141456GO:0016528
GeneOntologyCellularComponentGolgi-associated vesicle

PCLO AP1M2 BACE1 CUBN CNGA4 UNC13A

1.45e-041141456GO:0005798
GeneOntologyCellularComponentcell cortex region

UNC13B PCLO UNC13C UNC13A

2.65e-04451454GO:0099738
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1B CACNA1F CACNA1S CACNA1G

2.89e-04461454GO:0005891
GeneOntologyCellularComponentsarcoplasmic reticulum

CACNA1S H6PD RYR2 ITPR1 ATP2A1

3.70e-04881455GO:0016529
GeneOntologyCellularComponentextrinsic component of plasma membrane

CDHR3 CUBN RYR2 AP2S1 TOLLIP CDH10

3.92e-041371456GO:0019897
GeneOntologyCellularComponentcone cell pedicle

PCLO RAPGEF4

4.71e-0451452GO:0044316
GeneOntologyCellularComponentintracellular canaliculus

KCNA5 ABCB11

4.71e-0451452GO:0046691
GeneOntologyCellularComponentmyofibril

CACNA1S RYR2 MYLK2 KCNA5 MTM1 TNNC2 ATP2A1 ALPP

6.51e-042731458GO:0030016
GeneOntologyCellularComponentpresynaptic membrane

UNC13B NTNG2 AP2S1 KCNA3 UNC13C FBXO45 CDH10 UNC13A

7.16e-042771458GO:0042734
GeneOntologyCellularComponentcontractile muscle fiber

CACNA1S RYR2 MYLK2 KCNA5 MTM1 TNNC2 ATP2A1 ALPP

9.63e-042901458GO:0043292
GeneOntologyCellularComponentextrinsic component of membrane

CDHR3 CUBN RYR2 AP2S1 TOLLIP KIAA1755 CDH10

1.14e-032301457GO:0019898
GeneOntologyCellularComponentmembrane protein complex

CACNA1B CACNA1F CACNA1S HLA-DOB KCNV2 CDHR3 AP1M2 NDUFS2 RHAG RYR2 AP4S1 AP2S1 KCNA3 KCNA5 NALCN KCNQ4 SCN7A CACNA1G ATP2A1 CNGA4 CDH10

1.57e-03149814521GO:0098796
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ATP2A1

1.67e-0391452GO:0031095
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

RSPH4A TULP3 MAPK15 WDR35 KIF5B KIF5C TRAK2 RSPH10B

1.69e-033171458GO:0032838
GeneOntologyCellularComponentsarcomere

CACNA1S RYR2 MYLK2 KCNA5 MTM1 TNNC2 ATP2A1

1.79e-032491457GO:0030017
GeneOntologyCellularComponentdendrite cytoplasm

KIF5B KIF5C TRAK2

2.49e-03391453GO:0032839
GeneOntologyCellularComponentnon-motile cilium

CACNA1F RAPGEF4 ADGRV1 PTGS1 TULP3 CNGA4

2.49e-031961456GO:0097730
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ATP2A1

2.52e-03111452GO:0031094
GeneOntologyCellularComponentplasma membrane protein complex

CACNA1B CACNA1F CACNA1S HLA-DOB KCNV2 CDHR3 AP2S1 KCNA3 KCNA5 KCNQ4 SCN7A CACNA1G CDH10

3.26e-0378514513GO:0098797
GeneOntologyCellularComponentvoltage-gated potassium channel complex

KCNV2 KCNA3 KCNA5 KCNQ4

3.72e-03911454GO:0008076
GeneOntologyCellularComponentpostsynaptic cytosol

KIF5B KIF5C FBXO45

3.75e-03451453GO:0099524
GeneOntologyCellularComponentaxonal growth cone

KIF5B KIF5C TRAK2

3.75e-03451453GO:0044295
GeneOntologyCellularComponentGolgi apparatus subcompartment

PCLO AP1M2 BACE1 GAL3ST4 ATL1 AP4S1 RAB34 GAL3ST3 USP6NL

3.82e-034431459GO:0098791
GeneOntologyCellularComponent9+0 non-motile cilium

CACNA1F RAPGEF4 ADGRV1 PTGS1 TULP3

4.31e-031531455GO:0097731
GeneOntologyCellularComponentAP-type membrane coat adaptor complex

AP1M2 AP4S1 AP2S1

4.50e-03481453GO:0030119
GeneOntologyCellularComponentglutamatergic synapse

UNC13B CUL3 CACNA1B PCLO RAPGEF4 NTNG2 AP2S1 KCNA3 GRK2 PLCG1 FBXO45 CDH10 UNC13A

4.56e-0381714513GO:0098978
MousePhenoabnormal channel response

CACNA1B BACE1 KCNA5 NALCN CACNA1G

8.40e-06331205MP:0003484
DomainIon_trans_dom

CACNA1B CACNA1F CACNA1S KCNV2 RYR2 ITPR1 KCNA3 KCNA5 NALCN KCNQ4 SCN7A CACNA1G CNGA4

3.65e-1211414213IPR005821
DomainIon_trans

CACNA1B CACNA1F CACNA1S KCNV2 RYR2 ITPR1 KCNA3 KCNA5 NALCN KCNQ4 SCN7A CACNA1G CNGA4

3.65e-1211414213PF00520
DomainChannel_four-helix_dom

CACNA1B CACNA1F CACNA1S KCNV2 KCNA3 KCNA5 NALCN SCN7A CACNA1G

4.34e-10571429IPR027359
Domain-

CACNA1B CACNA1F CACNA1S KCNV2 KCNA3 KCNA5 NALCN SCN7A CACNA1G

4.34e-105714291.20.120.350
DomainUnc-13

UNC13B UNC13C UNC13A

4.30e-0731423IPR027080
DomainVDCCAlpha1

CACNA1B CACNA1F CACNA1S CACNA1G

6.49e-07101424IPR002077
DomainMunc13_dom-2

UNC13B UNC13C UNC13A

4.26e-0651423IPR014772
DomainMHD2

UNC13B UNC13C UNC13A

4.26e-0651423PS51259
DomainMunc13_subgr_dom-2

UNC13B UNC13C UNC13A

4.26e-0651423IPR019558
DomainMembr_traf_MHD

UNC13B UNC13C UNC13A

4.26e-0651423PF10540
DomainDUF1041

UNC13B UNC13C UNC13A

4.26e-0651423SM01145
DomainC2

UNC13B PCLO PLCL2 TOLLIP UNC13C PLCL1 PLCG1 UNC13A

7.21e-061311428PF00168
DomainC2

UNC13B PCLO PLCL2 TOLLIP UNC13C PLCL1 PLCG1 UNC13A

1.00e-051371428SM00239
DomainC2

UNC13B PCLO PLCL2 TOLLIP UNC13C PLCL1 PLCG1 UNC13A

1.30e-051421428PS50004
DomainMunc13_1

UNC13B UNC13C UNC13A

1.47e-0571423IPR014770
DomainMHD1

UNC13B UNC13C UNC13A

1.47e-0571423PS51258
DomainCa_chan_IQ

CACNA1B CACNA1F CACNA1S

1.47e-0571423SM01062
DomainCa_chan_IQ

CACNA1B CACNA1F CACNA1S

1.47e-0571423PF08763
DomainDUF1041

UNC13B UNC13C UNC13A

1.47e-0571423PF06292
DomainVDCC_a1su_IQ

CACNA1B CACNA1F CACNA1S

1.47e-0571423IPR014873
DomainGPHH

CACNA1B CACNA1F CACNA1S

1.47e-0571423PF16905
DomainCAPS_dom

UNC13B UNC13C UNC13A

1.47e-0571423IPR010439
DomainGPHH_dom

CACNA1B CACNA1F CACNA1S

1.47e-0571423IPR031649
Domain-

UNC13B PCLO PLCL2 TOLLIP UNC13C PLCL1 PLCG1 UNC13A

1.76e-0514814282.60.40.150
DomainC2_dom

UNC13B PCLO PLCL2 TOLLIP UNC13C PLCL1 PLCG1 UNC13A

3.69e-051641428IPR000008
DomainIFRD_C

IFRD1 IFRD2

5.74e-0521422PF04836
DomainIFRD

IFRD1 IFRD2

5.74e-0521422PF05004
DomainInterferon-rel_develop_reg_C

IFRD1 IFRD2

5.74e-0521422IPR006921
DomainKCC1

SLC12A6 SLC12A4

5.74e-0521422IPR000622
DomainInterferon-rel_develop_reg_N

IFRD1 IFRD2

5.74e-0521422IPR007701
DomainEF-hand-dom_pair

CACNA1B CACNA1F CACNA1S TBC1D9B RYR2 SCN7A PLCL2 TNNC2 PLCL1 PLCG1

7.01e-0528714210IPR011992
DomainVG_K_chnl

KCNV2 KCNA3 KCNA5 KCNQ4

1.10e-04331424IPR028325
DomainEF-hand_like

PLCL2 PLCL1 PLCG1

1.83e-04151423PF09279
DomainPI-PLC-Y

PLCL2 PLCL1 PLCG1

1.83e-04151423PF00387
DomainPLCYc

PLCL2 PLCL1 PLCG1

1.83e-04151423SM00149
DomainPLipase_C_Pinositol-sp_Y

PLCL2 PLCL1 PLCG1

1.83e-04151423IPR001711
DomainPIPLC_Y_DOMAIN

PLCL2 PLCL1 PLCG1

1.83e-04151423PS50008
DomainPI-PLC_fam

PLCL2 PLCL1 PLCG1

1.83e-04151423IPR001192
DomainPLC_EF-hand-like

PLCL2 PLCL1 PLCG1

1.83e-04151423IPR015359
DomainAP_mu_sigma_su

AP1M2 AP4S1 AP2S1

2.24e-04161423IPR022775
DomainClat_adaptor_s

AP1M2 AP4S1 AP2S1

2.24e-04161423PF01217
DomainPI-PLC-X

PLCL2 PLCL1 PLCG1

3.23e-04181423PF00388
DomainPLCXc

PLCL2 PLCL1 PLCG1

3.23e-04181423SM00148
DomainVDCC_L_a1su

CACNA1F CACNA1S

3.41e-0441422IPR005446
DomainGal-3-0_sulfotr

GAL3ST4 GAL3ST3

3.41e-0441422PF06990
DomainGal-3-0_sulfotransfrase

GAL3ST4 GAL3ST3

3.41e-0441422IPR009729
DomainKCL_cotranspt

SLC12A6 SLC12A4

3.41e-0441422IPR000076
DomainPIPLC_X_DOMAIN

PLCL2 PLCL1 PLCG1

3.81e-04191423PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCL2 PLCL1 PLCG1

3.81e-04191423IPR000909
DomainTBC

TBC1D9B EVI5 USP6NL EVI5L

5.20e-04491424SM00164
DomainAmmonium_transpt

RHCG RHAG

5.65e-0451422IPR001905
DomainCPSASE_1

CAD ACACA

5.65e-0451422PS00866
DomainAmmonium_transp

RHCG RHAG

5.65e-0451422PF00909
DomainNH4_transpt_AmtB-like_dom

RHCG RHAG

5.65e-0451422IPR024041
DomainRhesusRHD

RHCG RHAG

5.65e-0451422IPR002229
DomainRabGAP-TBC

TBC1D9B EVI5 USP6NL EVI5L

7.02e-04531424PF00566
DomainRab-GTPase-TBC_dom

TBC1D9B EVI5 USP6NL EVI5L

8.09e-04551424IPR000195
DomainTBC_RABGAP

TBC1D9B EVI5 USP6NL EVI5L

8.09e-04551424PS50086
DomainRIH_assoc-dom

RYR2 ITPR1

8.44e-0461422IPR013662
DomainIns145_P3_rec

RYR2 ITPR1

8.44e-0461422PF08709
DomainRIH_assoc

RYR2 ITPR1

8.44e-0461422PF08454
DomainRIH_dom

RYR2 ITPR1

8.44e-0461422IPR000699
DomainIns145_P3_rcpt

RYR2 ITPR1

8.44e-0461422IPR014821
DomainRyanodine_recept-rel

RYR2 ITPR1

8.44e-0461422IPR015925
DomainCPSASE_2

CAD ACACA

8.44e-0461422PS00867
Domain-

RYR2 ITPR1

8.44e-04614221.25.10.30
DomainRYDR_ITPR

RYR2 ITPR1

8.44e-0461422PF01365
DomainPH_12

PLCL2 PLCL1

8.44e-0461422PF16457
Domain-

PLCL2 PLCL1 PLCG1

8.75e-042514233.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

PLCL2 PLCL1 PLCG1

8.75e-04251423IPR017946
DomainC1_1

UNC13B PRKD3 UNC13C UNC13A

9.26e-04571424PF00130
DomainK_chnl_volt-dep_Kv

KCNV2 KCNA3 KCNA5

1.10e-03271423IPR003968
DomainAnoct_dimer

ANO4 ANO7

1.18e-0371422PF16178
DomainAnoct_dimer

ANO4 ANO7

1.18e-0371422IPR032394
DomainCbamoylP_synth_lsu-like_ATP-bd

CAD ACACA

1.18e-0371422IPR005479
DomainBC-like_N

CAD ACACA

1.18e-0371422IPR005481
DomainSLC12A_fam

SLC12A6 SLC12A4

1.18e-0371422IPR004842
Domain-

RHCG RHAG

1.18e-03714221.10.3430.10
DomainCPSase_L_D2

CAD ACACA

1.18e-0371422PF02786
DomainAmmonium/urea_transptr

RHCG RHAG

1.18e-0371422IPR029020
DomainBiotin_carb_N

CAD ACACA

1.18e-0371422PF00289
DomainAP_complex_ssu

AP4S1 AP2S1

1.18e-0371422IPR016635
DomainLongin-like_dom

AP1M2 AP4S1 AP2S1

1.23e-03281423IPR011012
DomainZF_DAG_PE_1

UNC13B PRKD3 UNC13C UNC13A

1.43e-03641424PS00479
DomainZF_DAG_PE_2

UNC13B PRKD3 UNC13C UNC13A

1.43e-03641424PS50081
DomainC1

UNC13B PRKD3 UNC13C UNC13A

1.51e-03651424SM00109
DomainSLC12_C

SLC12A6 SLC12A4

1.56e-0381422IPR018491
DomainP_TREFOIL_1

SI ZP1

1.56e-0381422PS00025
DomainK_chnl_volt-dep_Kv1

KCNA3 KCNA5

1.56e-0381422IPR003972
DomainSLC12

SLC12A6 SLC12A4

1.56e-0381422PF03522
DomainP_trefoil_CS

SI ZP1

1.56e-0381422IPR017957
DomainPE/DAG-bd

UNC13B PRKD3 UNC13C UNC13A

1.60e-03661424IPR002219
DomainCLAT_ADAPTOR_S

AP4S1 AP2S1

2.00e-0391422PS00989
DomainP_TREFOIL_2

SI ZP1

2.00e-0391422PS51448
DomainPD

SI ZP1

2.00e-0391422SM00018
DomainP-loop_NTPase

GAL3ST4 NMRK2 ATL1 NLRP14 RAB34 ABCB9 SUPV3L1 DDX54 GAL3ST3 ABCB11 DDX3Y KIF5B KIF5C DHX29 RAD17

2.03e-0384814215IPR027417
DomainMIR

RYR2 ITPR1

2.48e-03101422PF02815
DomainMIF4G

NCBP1 EIF4G1

2.48e-03101422SM00543
DomainMIR_motif

RYR2 ITPR1

2.48e-03101422IPR016093
DomainMIF4G

NCBP1 EIF4G1

2.48e-03101422PF02854
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1B CACNA1F CACNA1S RYR2 MYLK2 ITPR1 MYLK3 CACNA1G TNNC2 PLCG1 ATP2A1

3.36e-0717812011M2890
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1B CACNA1F CACNA1S

1.18e-0561203M47762
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1B CACNA1F CACNA1S CACNA1G

3.90e-05231204M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1B CACNA1F CACNA1S CACNA1G

5.50e-05251204M47948
PathwayWP_SYNAPTIC_VESICLE_PATHWAY

UNC13B CACNA1B AP2S1 UNC13C UNC13A

7.06e-05511205M39457
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1B CACNA1S RYR2

9.44e-05111203M47958
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1B CACNA1F CACNA1S KCNV2 RYR2 KCNA3 KCNA5 KCNQ4 SCN7A CACNA1G

4.47e-101391471016985003
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1B CACNA1F RYR2 ITPR1 CACNA1G ATP2A1

1.27e-0838147630786075
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1B CACNA1F CACNA1S CACNA1G

2.12e-088147428330839
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1B CACNA1F CACNA1S CACNA1G

3.80e-089147416382099
Pubmed

AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.

CACNA1S RYR2 MTM1 ATP2A1

6.31e-0810147418434328
Pubmed

Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.

UNC13B UNC13C UNC13A

7.40e-083147333105896
Pubmed

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.

UNC13B UNC13C UNC13A

7.40e-083147323658173
Pubmed

Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.

UNC13B UNC13C UNC13A

7.40e-083147322966208
Pubmed

Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.

UNC13B UNC13C UNC13A

7.40e-083147315988013
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DOCK3 CACNA1B CAD ACACA PCLO NDUFS2 RYR2 ATL1 ITPR1 ARFGAP2 TRAP1 AP2S1 ERLIN2 GRK2 KIF5B PSMD14 DHX29 CLEC16A UNC13A HDAC2

7.84e-0811391472036417873
Pubmed

GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin.

KIF5B KIF5C TRAK2

2.95e-074147315644324
Pubmed

Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.

UNC13B FBXO45 UNC13A

2.95e-074147319996097
Pubmed

Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing.

UNC13B BACE1 UNC13A

2.95e-074147315123597
Pubmed

An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.

UNC13B UNC13C UNC13A

7.35e-075147334706221
Pubmed

Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.

UNC13B UNC13C UNC13A

7.35e-075147326575293
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

CAD ACACA ACO1 PCLO AP1M2 NCBP1 ME1 TARDBP TRAP1 ERLIN2 EIF4G1 CACNA1G PSMD14 ATP2A1 IQGAP3

1.85e-068071471530575818
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

CAD ACACA HSP90AB4P AP1M2 MYLK2 TARDBP TRAP1 DDX3Y ATP2A1 HDAC2

2.25e-063441471036282215
Pubmed

Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.

UNC13B UNC13C UNC13A

2.56e-067147336398873
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1F CACNA1S CACNA1G

2.56e-067147312900400
Pubmed

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.

UNC13B UNC13C UNC13A

4.08e-068147325609709
Pubmed

The synaptic vesicle cycle.

UNC13B PCLO UNC13C UNC13A

8.82e-0631147415217342
Pubmed

Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.

EPB41L5 MYLK2 ARFGAP2 VPS13D EIF4G1 DDX54 DDX3Y HDAC2

1.04e-05245147821182205
Pubmed

Mutations in C1orf194, encoding a calcium regulator, cause dominant Charcot-Marie-Tooth disease.

CACNA1S TNNC2 ATP2A1

1.19e-0511147331199454
Pubmed

Molecular and functional architecture of striatal dopamine release sites.

UNC13B UNC13C UNC13A

1.19e-0511147334767769
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

SLC12A6 PCLO NDUFS2 ATL1 ITPR1 TARDBP TRAP1 GRK2 TOLLIP DDX3Y KIF5B KIF5C

1.42e-056211471222794259
Pubmed

Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.

SLC12A6 SLC12A4

1.77e-052147234031912
Pubmed

Myosin light chain kinase and myosin phosphorylation effect frequency-dependent potentiation of skeletal muscle contraction.

MYLK2 MYLK3

1.77e-052147216299103
Pubmed

Phospholipase C-related but catalytically inactive protein acts as a positive regulator of insulin signalling in adipocytes.

PLCL2 PLCL1

1.77e-052147234859819
Pubmed

eIF4G and CBP80 share a common origin and similar domain organization: implications for the structure and function of eIF4G.

NCBP1 EIF4G1

1.77e-052147216156639
Pubmed

Phospholipase C-related catalytically inactive protein regulates lipopolysaccharide-induced hypothalamic inflammation-mediated anorexia in mice.

PLCL2 PLCL1

1.77e-052147231589911
Pubmed

Regulation of insulin exocytosis by Munc13-1.

UNC13B UNC13A

1.77e-052147212871971
Pubmed

The Rh complex exports ammonium from human red blood cells.

RHCG RHAG

1.77e-052147212846905
Pubmed

Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.

UNC13B UNC13A

1.77e-052147217561838
Pubmed

Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.

UNC13B UNC13A

1.77e-052147228489077
Pubmed

Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.

UNC13B UNC13A

1.77e-052147210440375
Pubmed

Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.

UNC13B UNC13A

1.77e-052147222066784
Pubmed

Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34.

UNC13B RAB34

1.77e-052147223197834
Pubmed

Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses.

UNC13B UNC13A

1.77e-052147232187536
Pubmed

The challenge of understanding ammonium homeostasis and the role of the Rh glycoproteins.

RHCG RHAG

1.77e-052147216564724
Pubmed

Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets.

UNC13B UNC13A

1.77e-052147222814762
Pubmed

Interaction of eukaryotic translation initiation factor 4G with the nuclear cap-binding complex provides a link between nuclear and cytoplasmic functions of the m(7) guanosine cap.

NCBP1 EIF4G1

1.77e-052147211340157
Pubmed

Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.

UNC13B UNC13A

1.77e-052147228426965
Pubmed

Phospholipase C-related but catalytically inactive protein is required for insulin-induced cell surface expression of gamma-aminobutyric acid type A receptors.

PLCL2 PLCL1

1.77e-052147219996098
Pubmed

Potassium channels Kv1.3 and Kv1.5 are expressed on blood-derived dendritic cells in the central nervous system.

KCNA3 KCNA5

1.77e-052147216729292
Pubmed

Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.

UNC13B UNC13A

1.77e-052147223770256
Pubmed

Myocardin-Dependent Kv1.5 Channel Expression Prevents Phenotypic Modulation of Human Vessels in Organ Culture.

KCNA3 KCNA5

1.77e-052147231597447
Pubmed

Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.

UNC13B UNC13C

1.77e-052147222674279
Pubmed

Calcium-Independent Exo-endocytosis Coupling at Small Central Synapses.

UNC13B UNC13A

1.77e-052147231851910
Pubmed

Identification and characterization of a new phospholipase C-like protein, PLC-L(2).

PLCL2 PLCL1

1.77e-052147210581172
Pubmed

Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia.

SLC12A6 SLC12A4

1.77e-052147231835175
Pubmed

Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.

UNC13B UNC13A

1.77e-052147211832228
Pubmed

Munc13 controls the location and efficiency of dense-core vesicle release in neurons.

UNC13B UNC13A

1.77e-052147223229896
Pubmed

IQGAP3 interacts with Rad17 to recruit the Mre11-Rad50-Nbs1 complex and contributes to radioresistance in lung cancer.

IQGAP3 RAD17

1.77e-052147232896617
Pubmed

Expression of voltage-gated potassium channels Kv1.3 and Kv1.5 in human gliomas.

KCNA3 KCNA5

1.77e-052147212850541
Pubmed

Mapping the GRIF-1 binding domain of the kinesin, KIF5C, substantiates a role for GRIF-1 as an adaptor protein in the anterograde trafficking of cargoes.

KIF5C TRAK2

1.77e-052147216835241
Pubmed

Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34.

UNC13B RAB34

1.77e-052147216138900
Pubmed

Kv1.3/Kv1.5 heteromeric channels compromise pharmacological responses in macrophages.

KCNA3 KCNA5

1.77e-052147217157812
Pubmed

Genomic structure, sequence, and physiological expression of mKv 1.5, a mouse potassium channel gene.

ITPR1 KCNA5

1.77e-05214729302515
Pubmed

Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.

UNC13B UNC13A

1.77e-052147212070347
Pubmed

Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.

UNC13B UNC13A

1.77e-052147223070049
Pubmed

Phospholipase C-related inactive protein is involved in trafficking of gamma2 subunit-containing GABA(A) receptors to the cell surface.

PLCL2 PLCL1

1.77e-052147217301177
Pubmed

Involvement of phospholipase C-related inactive protein in the mouse reproductive system through the regulation of gonadotropin levels.

PLCL2 PLCL1

1.77e-052147219553601
Pubmed

Genetic reduction of GABA(A) receptor gamma2 subunit expression potentiates the immobilizing action of isoflurane.

PLCL2 PLCL1

1.77e-052147220097266
Pubmed

Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.

UNC13B UNC13A

1.77e-052147228772123
Pubmed

Differential expression of Kv1.3 and Kv1.5 voltage-dependent K+ channels in human skeletal muscle sarcomas.

KCNA3 KCNA5

1.77e-052147222360360
Pubmed

Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.

UNC13B UNC13A

1.77e-052147217267576
Pubmed

Voltage-dependent potassium channels Kv1.3 and Kv1.5 in human fetus.

KCNA3 KCNA5

1.77e-052147220798505
Pubmed

Cloning of the human interferon-related developmental regulator (IFRD1) gene coding for the PC4 protein, a member of a novel family of developmentally regulated genes.

IFRD1 IFRD2

1.77e-05214729722946
Pubmed

Association of Kv1.5 and Kv1.3 contributes to the major voltage-dependent K+ channel in macrophages.

KCNA3 KCNA5

1.77e-052147217038323
Pubmed

Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice.

SLC12A6 SLC12A4

1.77e-052147217510708
Pubmed

Phospholipase C-related inactive protein is implicated in the constitutive internalization of GABAA receptors mediated by clathrin and AP2 adaptor complex.

PLCL2 PLCL1

1.77e-052147217254016
Pubmed

A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution.

UNC13B UNC13A

1.77e-052147235613050
Pubmed

Membrane bridging by Munc13-1 is crucial for neurotransmitter release.

UNC13B UNC13A

1.77e-052147230816091
Pubmed

Rab34 and its effector munc13-2 constitute a new pathway modulating protein secretion in the cellular response to hyperglycemia.

UNC13B RAB34

1.77e-052147219641095
Pubmed

TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A.

TARDBP UNC13A

1.77e-052147235197626
Pubmed

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A.

TARDBP UNC13A

1.77e-052147235197628
Pubmed

A common molecular basis for membrane docking and functional priming of synaptic vesicles.

UNC13B UNC13A

1.77e-052147219558619
Pubmed

Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C.

UNC13B UNC13A

1.77e-052147218701688
Pubmed

RhCG is downregulated in oesophageal squamous cell carcinomas, but expressed in multiple squamous epithelia.

RHCG RHAG

1.77e-052147212204676
Pubmed

Isolation of cDNA clones for a 50 kDa glycoprotein of the human erythrocyte membrane associated with Rh (rhesus) blood-group antigen expression.

RHCG RHAG

1.77e-05214721417776
Pubmed

Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.

UNC13B UNC13A

1.77e-052147211792326
Pubmed

The Evi5 family in cellular physiology and pathology.

EVI5 EVI5L

1.77e-052147223669355
Pubmed

The human Rhesus-associated RhAG protein and a kidney homologue promote ammonium transport in yeast.

RHCG RHAG

1.77e-052147211062476
Pubmed

High-content RNAi screening identifies the Type 1 inositol triphosphate receptor as a modifier of TDP-43 localization and neurotoxicity.

ITPR1 TARDBP

1.77e-052147222872699
Pubmed

Kif5b is an essential forward trafficking motor for the Kv1.5 cardiac potassium channel.

KCNA5 KIF5B

1.77e-052147219675065
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCNV2 KCNA3 KCNA5 KCNQ4

2.49e-0540147416382104
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1B CACNA1F CACNA1S

3.24e-0515147320188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1B CACNA1F CACNA1S

3.24e-0515147324453333
Pubmed

Functional dissection of Rab GTPases involved in primary cilium formation.

TBC1D9B EVI5 USP6NL EVI5L

3.33e-0543147417646400
Pubmed

Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.

TBC1D9B EVI5 USP6NL EVI5L

3.33e-0543147419077034
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

CAD ACACA HSP90AB4P PCLO NCBP1 NDUFS2 TARDBP TRAP1 ERLIN2 MAPK15 SUPV3L1 EIF4G1 DDX54 PLCG1 KIF5B PSMD14 DHX29 IQGAP3

3.46e-0514251471830948266
Pubmed

Differential physiological roles for BIN1 isoforms in skeletal muscle development, function and regeneration.

CACNA1S MTM1 ATP2A1

3.98e-0516147332994313
Pubmed

Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes.

KIF5B KIF5C

5.31e-053147217693257
Pubmed

Phospholipase C-related but catalytically inactive protein modulates pain behavior in a neuropathic pain model in mice.

PLCL2 PLCL1

5.31e-053147223639135
Pubmed

Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited.

BACE1 KIF5B

5.31e-053147215745965
Pubmed

Munc13-3 Is Required for the Developmental Localization of Ca2+ Channels to Active Zones and the Nanopositioning of Cav2.1 Near Release Sensors.

CACNA1B UNC13C

5.31e-053147229466725
Pubmed

Potassium Channels Kv1.3 and Kir2.1 But Not Kv1.5 Contribute to BV2 Cell Line and Primary Microglial Migration.

KCNA3 KCNA5

5.31e-053147233669857
Pubmed

Cloning and localization of a conventional kinesin motor expressed exclusively in neurons.

KIF5B KIF5C

5.31e-05314727514426
Pubmed

Identification of physiologically relevant substrates for cloned Gal: 3-O-sulfotransferases (Gal3STs): distinct high affinity of Gal3ST-2 and LS180 sulfotransferase for the globo H backbone, Gal3ST-3 for N-glycan multiterminal Galbeta1, 4GlcNAcbeta units and 6-sulfoGalbeta1, 4GlcNAcbeta, and Gal3ST-4 for the mucin core-2 trisaccharide.

GAL3ST4 GAL3ST3

5.31e-053147214701868
Pubmed

Phosphoprotein Phosphatase 1 Is Required for Extracellular Calcium-Induced Keratinocyte Differentiation.

PIP5K1A PLCG1

5.31e-053147227340655
GeneFamilyUNC13 homologs

UNC13B UNC13C UNC13A

3.86e-074843836
GeneFamilyCalcium voltage-gated channel subunits

CACNA1B CACNA1F CACNA1S CACNA1G

6.00e-0626844253
GeneFamilyPotassium voltage-gated channels

KCNV2 KCNA3 KCNA5 KCNQ4

3.49e-0540844274
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCL2 PLCL1 PLCG1

8.88e-0519843832
GeneFamilyAnoctamins

ANO4 ANO7

9.37e-0410842865
GeneFamilyATP binding cassette subfamily B

ABCB9 ABCB11

1.14e-0311842806
GeneFamilyEF-hand domain containing

CACNA1B TBC1D9B RYR2 TNNC2 PLCG1

3.54e-03219845863
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK6 RSPH4A PCLO ADGRV1 CUBN RYR2 NALCN UNC13C MMP3

5.31e-09169147912bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

DOCK3 CACNA1B NOL4 PCLO GALNT13 NALCN KIF5C UNC13A

1.70e-07182147857bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR1 AP1M2 KCNA3 SCN7A PLCG1 MMP3

3.62e-078414766c8018d65df335c81fe4099a34e0053c8dbcf88d
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

CACNA1S GTF2IRD1 MYLK2 KCNQ4 UNC13C ITIH6 ATP2A1

8.55e-071551477d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellCOPD-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

ANO4 CACNA1B NOL4 RAPGEF4 GALNT13 NALCN KIF5C

2.23e-061791477988d0853c391da1e5004f73f3678047418d3f6d3
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F NOL4 PCLO ADGRV1 GALNT13 RYR2 UNC13C

2.68e-0618414772cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F NOL4 PCLO ADGRV1 GALNT13 RYR2 UNC13C

2.68e-061841477ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F NOL4 PCLO ADGRV1 GALNT13 RYR2 UNC13C

2.68e-0618414772b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

HGD ACACA NR6A1 ADGRV1 UNC13C PLCL1 RNF145

2.68e-061841477102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellmegakaryocytic|World / Lineage and Cell class

HGD AP1M2 OVOS2 PTGS1 RYR2 TNNC2 CTDSPL

2.68e-061841477b1c630ca2189d9d49402a5621b57618976fbea5c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

UNC13B ACACA EPB41L5 ADGRV1 UNC13C PLCL1 RNF145

2.78e-061851477673f0c688ae6984bc8027df2da335787924f4137
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B ACACA EPB41L5 NR6A1 ADGRV1 PLCL1 RNF145

2.78e-06185147798b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1B NOL4 PCLO RAPGEF4 GALNT13 KIF5C UNC13A

2.88e-061861477b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

UNC13B ACACA EPB41L5 NR6A1 ADGRV1 PLCL1 RNF145

2.99e-06187147781cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1B NOL4 PCLO GALNT13 NALCN KIF5C UNC13A

3.09e-061881477c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell10x5'v1-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HGD NPR3 PTGS1 RHAG RYR2 KCNQ4 CTDSPL

3.09e-061881477c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B DOCK3 NOL4 PCLO RAPGEF4 ADGRV1 KIF5C

3.80e-061941477b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANO4 CACNA1B NOL4 GALNT13 RYR2 PLCL1 UNC13A

4.21e-0619714773a0e97bfebe82f9687d518baaad7f20d0ffea8a1
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1S NMRK2 MYLK2 KCNQ4 UNC13C ATP2A1

8.45e-061441476f92e03dd784e31a9e5dbd4f4c3a6517ea19210cf
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 NOL4 PCLO GALNT13 KIF5C UNC13A

1.49e-0515914767747cef94c55144fddcd024a7495318357f1351b
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK3 CACNA1B NOL4 GALNT13 NALCN UNC13A

1.77e-051641476be49af6335f2505065cde2cb9800e4a5516811b1
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NOL4 KCNQ4 ANO7 KIF5C CDH10 UNC13A

2.10e-05169147696a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1B NOL4 GALNT13 KIF5C CDH10 UNC13A

2.10e-051691476b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCelldroplet-Kidney-nan-3m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD ACY3 CUBN ME1 TRAP1 TNNC2

2.17e-051701476dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S RSPH4A MAPK15 SCN7A CCNA1 CNGA4

2.39e-051731476a7cc63bb3ab41feb9e4072700d44dbbbc62c47c6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S RSPH4A MAPK15 SCN7A CCNA1 CNGA4

2.39e-051731476e3e3a67a5a93ef4475224a256d45ae24526383cc
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACA RAPGEF4 H6PD TM6SF2 ME1 ABCB11

2.55e-0517514765c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF4 RYR2 UNC13C KIF5C MMP3 RSBN1L

2.55e-05175147665571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 HGD NOL4 CDHR3 CUBN KIAA1755

2.72e-0517714762f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellIIF-Other-Platelet|IIF / Disease, Lineage and Cell Type

HGD AP1M2 OVOS2 PTGS1 TNNC2 CTDSPL

2.81e-051781476529c0d2159e539546876246122f2e999170a6b20
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACACA EPB41L5 NR6A1 ADGRV1 PLCL1 RNF145

2.81e-051781476f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HGD NOL4 ACY3 ADGRV1 CUBN KIAA1755

3.28e-051831476d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DOK6 HGD PTGS1 FHOD1 TNNC2 CTDSPL

3.28e-0518314766cbc88c27dc957d182526e84824f70c8e860bf74
ToppCell15-Distal-Immune-Hematopoietic,_B_Cells|Distal / Age, Tissue, Lineage and Cell class

HGD HLA-DOB ACY3 PTGS1 RHAG KCNQ4

3.38e-051841476c294cd421f277992b56ae9c40b8f3948e33148fe
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 HGD NOL4 CDHR3 CUBN KIAA1755

3.38e-0518414769434731f651820b05335085582960f08fbf895de
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 NOL4 NPR3 CDHR3 CUBN KIAA1755

3.59e-051861476a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF4 ITPR1 UNC13C KIF5B KIF5C RSBN1L

3.59e-051861476a1ab273b01971d6a892912560d387685dd657179
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF4 ITPR1 UNC13C KIF5B KIF5C RSBN1L

3.70e-051871476ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

UNC13B DOCK3 PCLO ADGRV1 KIF5C CDH10

3.81e-051881476beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B DOCK3 PCLO ADGRV1 KIF5C CDH10

3.93e-0518914767659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPH4A CDHR3 MAPK15 CCNA1 CABCOCO1 RSPH10B

3.93e-05189147638cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B DOCK3 PCLO AP1M2 ADGRV1 KIF5C

4.04e-051901476c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCellILEUM-non-inflamed-(8)_Activated_fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

BACE1 PTGS1 WDR35 KIAA1755 MMP3 CTDSPL

4.04e-05190147639fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 DOCK3 RYR2 ITPR1 PLCL1 CTDSPL

4.16e-0519114767853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell10x5'v1-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DOK6 HGD NPR3 PTGS1 RYR2 CTDSPL

4.16e-0519114767edc22e7e70697fb22690699efb352577162709b
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPH4A CDHR3 MAPK15 CCNA1 CABCOCO1 RSPH10B

4.16e-05191147696483adb97c81208aa513782550acd8a08b63866
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B DOCK3 NOL4 PCLO RAPGEF4 ADGRV1

4.29e-051921476b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

UNC13B DOCK3 NOL4 AP1M2 ADGRV1 KIF5C

4.41e-051931476aa10924b203c71e65fdbd2b90ba131dbd362d8b1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCLO EPB41L5 NR6A1 CUBN GTF2IRD1 PLCL1

4.41e-05193147682e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B DOCK3 PCLO AP1M2 ADGRV1 KIF5C

4.54e-051941476f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellCOVID-19-Heart-Mito_CM|COVID-19 / Disease (COVID-19 only), tissue and cell type

NMRK2 RYR2 MYLK2 MYLK3 TNNC2 ATP2A1

4.95e-05197147644e49943d62bfe622b40ad0460093d31540544df
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANO4 DOK6 CDHR3 RYR2 NALCN SCN7A

4.95e-0519714766d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B PCLO RAPGEF4 RYR2 ITPR1 KIF5C

5.09e-051981476c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B PCLO RYR2 ITPR1 KIF5C UNC13A

5.09e-0519814768ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B DOK6 PCLO RAPGEF4 RYR2 KIF5C

5.09e-0519814760ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCelldistal-Epithelial-Ciliated-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RSPH4A CDHR3 MAPK15 MYLK3 CCNA1 CABCOCO1

5.09e-051981476d30d6c6a0a78b7571318b5b2a0186df96dd0f5a9
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B ACACA EPB41L5 NR6A1 ADGRV1 RNF145

5.23e-0519914768587bd98de7767a575088afbea07a1feb4516b9b
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B ACACA EPB41L5 NR6A1 ADGRV1 RNF145

5.23e-0519914765cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellLPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DOK6 HGD CUBN PTGS1 RHAG EVI5L

5.38e-052001476326cae37cacd94b423a6ac8873ea56c5abaf0a0b
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Cortical_neuron|6m / Sample Type, Dataset, Time_group, and Cell type.

DOK6 NOL4 PCLO ATL1 KIF5C UNC13A

5.38e-0520014766f7ff0533339fcc9d316f2c77334a79c1409ec4f
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Platelets-Platelets|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOK6 HGD SI PTGS1 RHAG

6.42e-05127147529d0b078b9fb151b2689263828a0a2f178196d16
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Platelets|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOK6 HGD SI PTGS1 RHAG

6.42e-051271475041fb924aa2138a86612e07a9a5759cbbe2446e0
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Acinar_Adenocarcinoma-7|TCGA-Lung / Sample_Type by Project: Shred V9

ANO4 SI NALCN SCN7A TRAK2

7.17e-0513014750219d0d5d21df08f816569c7eb34f1bfa095d29a
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Pitx2_(Subthalamic_nucleus_(STN))-|Thalamus / BrainAtlas - Mouse McCarroll V32

RHCG HGD AP1M2 LHX3

8.02e-0569147410d5fccc1fa10ffc9051df42dd0e5046d97ec4af
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Pitx2_(Subthalamic_nucleus_(STN))|Thalamus / BrainAtlas - Mouse McCarroll V32

RHCG HGD AP1M2 LHX3

8.02e-056914749d7e911434c6b18327fa7adaec5c449e0c300919
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Thalamus / BrainAtlas - Mouse McCarroll V32

HGD AP1M2 LHX3 NMRK2

8.97e-057114747623b110bc3db0f5b99803c8fbb881ae8846b817
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GTF2IRD1 ITPR1 SCN7A CCNA1 MMP3

1.09e-0414214755b6b0c611c83b23ef7289854a515b78f6cf84500
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-MyoFB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

CCNA1 ABCB11 MMP3 UNC13A RSPH10B

1.20e-041451475ac41c6c02b7d78162b86222983688f54d04ac47d
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1B SI ABCB11 UNC13C UNC13A

1.41e-0415014750205318a870e091add66ee4305747dda9f51510d
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTGS1 RHAG CCNA1 ANO7

1.57e-0482147442017b8ace6f142a8358213c95a2632226c3a867
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOL4 CDHR3 ADGRV1 GALNT13 UNC13A

1.64e-041551475498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CWF19L2 NPR3 KCNQ4 EIF4G1 DDX3Y

1.69e-041561475029ba0832ee9c4a2c85620e4df2260e02d86b45c
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CWF19L2 NPR3 KCNQ4 EIF4G1 DDX3Y

1.69e-0415614755df19a235843829f5a1a90ca21b0964ef8b4e115
ToppCell10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-LMPP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DOCK3 NPR3 ACY3 GAL3ST3 ATP2A1

1.69e-04156147596747447ba7dc2c10079cee44394b19ce60b2f41
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RHCG GTF2IRD1 ITPR1 UNC13C MMP3

1.79e-0415814757960337d87afecf2692ab65e5991f052ceddfacc
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

ANO4 GAL3ST4 H6PD KCNQ4 DDX3Y

1.85e-041591475b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCellASK440-Immune-B_cell|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

HLA-DOB CCNP ABCB9 SUPV3L1 PLCL1

1.85e-041591475d31eb59c1b5948df721b829b9a7e806f27cbd41c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B KCNV2 ADGRV1 GALNT13 RYR2

1.90e-041601475c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell368C-Myeloid-Dendritic-cDC_activated|368C / Donor, Lineage, Cell class and subclass (all cells)

DOCK3 HLA-DOB NR6A1 NUB1 PLCL1

1.90e-041601475bcd90ef96464bd901b87b94c696de70c113bfd03
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACA RAPGEF4 H6PD ME1 ABCB11

1.90e-041601475c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B KCNV2 ADGRV1 GALNT13 RYR2

1.90e-04160147525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

ADGRV1 GALNT13 VPS13D NTNG2 NALCN

1.96e-041611475347edb0de10850b7d16c40945751033289289c9b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK3 CUBN TULP3 PLCG1 TRAK2

1.96e-0416114755fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellfacs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK6 CUBN RHAG MYLK3 KIAA1755

2.19e-0416514754f95c2fe5ab4416c736fe0d1936695a2b26777eb
ToppCellfacs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK6 CUBN RHAG MYLK3 KIAA1755

2.19e-0416514753e913b49a868fdd5589200ae3e9be77c0938ba14
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B EPB41L5 NR6A1 ADGRV1 RNF145

2.25e-041661475c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNV2 PCLO RAPGEF4 NR6A1 MAPK15

2.25e-04166147566026988509e39e41274fa0de738383219e8ff30
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1B NOL4 CCNP KIF5C UNC13A

2.32e-041671475c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCelldroplet-Lung-LUNG-30m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 CACNA1S DDR1 TNNC2 IQGAP3

2.38e-0416814750e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACA RAPGEF4 H6PD ME1 ABCB11

2.38e-041681475b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACA RAPGEF4 H6PD ME1 ABCB11

2.38e-041681475073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDHR3 CUBN MYLK3 CCNA1 RSPH10B

2.45e-0416914758bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCellControl-Hematopoietic_Meg-Ery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTGS1 RHAG IFRD2 PLCL2 TRAK2

2.45e-041691475c2e2a7b89fe4a64d79efafdec037c4104f433061
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACA RAPGEF4 H6PD ME1 ABCB11

2.45e-041691475f195467438c589f87224bde7da720dea072d110c
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACA RAPGEF4 H6PD ME1 ABCB11

2.45e-0416914757785cab967a33560830c394c918d6ce625103858
ToppCellControl-Hematopoietic_Meg-Ery-Erythroid|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTGS1 RHAG IFRD2 PLCL2 TRAK2

2.45e-041691475df1fc1477bbbb285063b9b122b1ac84c87fd7fa8
ToppCellControl-Hematopoietic_Meg-Ery-Erythroid-Erythroid|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTGS1 RHAG IFRD2 PLCL2 TRAK2

2.45e-04169147592986559aa4a744e8b0487b0ae035cfb1fbf9890
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK3 NMRK2 RYR2 MYLK3 PLCL1

2.52e-0417014753f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B ACACA EPB41L5 ADGRV1 PLCL1

2.52e-041701475a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1S HLA-DOB ZP1 RAB34 TNNC2

2.52e-041701475bf589c4297ccc90e5f51e3d0fcc229548af4fcef
Drugbepridil

CACNA1B CACNA1F CACNA1S RYR2 MYLK2 ITPR1 ITFG1 MYLK3 KCNQ4 SCN7A CACNA1G TNNC2 ATP2A1 ALPP

7.86e-1412614614CID000002351
DrugN-cyclopentyl-N-cyclobutylformamide

CACNA1B CACNA1F CACNA1S NR6A1 RYR2 ITPR1 CCNA1 CACNA1G

4.19e-08791468CID005287890
DrugCNS 1145

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

6.02e-08331466CID000190902
DrugIHC-64

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

6.02e-08331466CID000162753
Drug8-bromoguanosine 3',5'-cyclic monophosphate

SLC12A6 CACNA1B CACNA1F CACNA1S NPR3 RYR2 MYLK2 ITPR1 PRKD3 GRK2 SLC12A4 CACNA1G ALPP

1.00e-0730814613CID000001915
Drugverapamil

CACNA1B CACNA1F CACNA1S KCNV2 RYR2 ITPR1 PRKD3 KCNA3 KCNA5 ABCB9 KCNQ4 SCN7A ABCB11 CACNA1G ATP2A1 ALPP

1.11e-0749014616CID000002520
DrugIAA-94

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 KCNA3 CACNA1G

1.26e-07611467CID000003667
Druglavendustin A

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 PRKD3 KCNA3 GRK2 KCNA5 CACNA1G

1.61e-0717114610CID000003894
DrugAC1L1KS5

CACNA1B CACNA1F CACNA1S NPR3 PTGS1 RYR2 ITPR1 PRKD3 MAPK15 GRK2 CACNA1G PLCG1 ATP2A1

2.54e-0733414613CID000005631
Drugpotassium

RHCG SLC12A6 CACNA1B CACNA1F CACNA1S DDR1 NPR3 KCNV2 RAPGEF4 RYR2 MYLK2 ITPR1 PRKD3 KCNA3 GRK2 KCNA5 SLC12A4 KCNQ4 SCN7A CACNA1G PLCG1 ATP2A1

4.87e-07100814622CID000000813
DrugBay K 8644

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 PRKD3 GRK2 CACNA1G ATP2A1

5.51e-071501469CID000002303
Druglamotrigine

CACNA1B CACNA1F CACNA1S PTGS1 RYR2 ITPR1 SCN7A CACNA1G

8.35e-071161468CID000003878
DrugCinildipine

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

1.56e-06561466CID000002752
Drugriluzole

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 TARDBP KCNA5 SCN7A CACNA1G

1.90e-061741469CID000005070
Drugnilvadipine

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

2.36e-06601466CID000004494
DrugU46619

CACNA1B CACNA1F CACNA1S NPR3 PTGS1 RYR2 MYLK2 ITPR1 PRKD3 CACNA1G PLCG1

2.39e-0628514611CID000005618
Drug3-(1H-pyrrole-2-carboxylate

CACNA1B CACNA1S NPR3 RAPGEF4 RYR2 ITPR1 PRKD3 GRK2 MYLK3 ATP2A1

2.73e-0623314610CID000005114
Druglanthanum

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 MAPK15 CACNA1G ATP2A1

2.78e-061361468CID000023926
DrugVerapamil

CACNA1B CACNA1F CACNA1S CACNA1G

2.78e-06161464DB00661
Drugisotetrandrine

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G ALPP

3.06e-06971467CID000005422
Druglercanidipine

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

3.15e-06631466CID000065866
Drugmag-fura-2

CACNA1S RAPGEF4 RYR2 ITPR1 ATP2A1

3.74e-06371465CID000123839
Drugisradipine

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 SCN7A CACNA1G

3.75e-061001467CID000003784
DrugD-myo-inositol-1,4,5-triphosphate

CACNA1B CACNA1F CACNA1S RYR2 MYLK2 ITPR1 PRKD3 ERLIN2 MAPK15 GRK2 PLCL2 CACNA1G PLCL1 PLCG1 ATP2A1

3.94e-0656814615CID000000806
Drugdihydropyridine

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 PRKD3 GRK2 CACNA1G ATP2A1

4.46e-061931469CID000104822
Drugnimodipine

CACNA1B CACNA1F CACNA1S RAPGEF4 RYR2 ITPR1 CACNA1G ATP2A1

4.48e-061451468CID000004497
Druggallopamil

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

4.54e-06671466CID000001234
Drugstrontium

CAD RYR2 ITPR1 PRKD3 TNNC2 ATP2A1

4.95e-06681466CID000104798
Drugloperamide

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 PRKD3 CACNA1G

5.20e-061051467CID000003954
DrugPiperacetazine [3819-00-9]; Down 200; 9.8uM; PC3; HT_HG-U133A

NPR3 PRKD3 VPS13D GRK2 MTM1 MIPEP DDX54 CCNA1 CLEC16A

5.27e-0619714695834_DN
DrugAC1L2AC7

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

5.39e-06691466CID000068733
Drugpyraclofos

CACNA1B CACNA1S KCNA3 KCNA5 KCNQ4 SCN7A CACNA1G

5.54e-061061467CID000093460
Drugprocaine

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 PRKD3 SCN7A CACNA1G

6.66e-061531468CID000004914
DrugCAS 298-57-7

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

7.50e-06731466CID000002761
Drugethosuximide

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

8.12e-06741466CID000003291
Drugcalmidazolium chloride

CACNA1B MYLK2 ITPR1 PRKD3 GRK2 MYLK3 TNNC2 ATP2A1

9.25e-061601468CID000002531
DrugAC1L1KC5

CACNA1B CACNA1F CACNA1S RAPGEF4 RYR2 MYLK2 ITPR1 PRKD3 MAPK15 KCNA3 GRK2 MYLK3 CACNA1G ATP2A1

1.06e-0554114614CID000005428
DrugAC1NBU2S

CACNA1B CACNA1F CACNA1S NPR3 RYR2 ITPR1 CACNA1G

1.06e-051171467CID004473765
Drugnisoldipine

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

1.10e-05781466CID000004499
Drugphenytoin

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 KCNA3 SCN7A CACNA1G MMP3

1.24e-052191469CID000001775
Druggabapentin

CACNA1B CACNA1F CACNA1S ACO1 RYR2 ITPR1 SCN7A CACNA1G

1.38e-051691468CID000003446
Drugnifedipine

CACNA1B CACNA1F CACNA1S ACO1 RYR2 MYLK2 ITPR1 PRKD3 GRK2 KCNA5 CACNA1G ATP2A1

1.57e-0541514612CID000004485
DrugXeC compound

CACNA1B CACNA1S RAPGEF4 RYR2 ITPR1 ATP2A1

1.69e-05841466CID000005701
Drugpapaverine

CACNA1B CACNA1F CACNA1S NPR3 RYR2 ITPR1 CACNA1G PLCG1

1.85e-051761468CID000004680
Drugchelerythrine

SLC12A6 NPR3 PTGS1 MYLK2 ITPR1 ITFG1 PRKD3 MAPK15 GRK2 KCNA5 SLC12A4

2.01e-0535714611CID000002703
DrugAC1L1GTT

CACNA1B RYR2 MYLK2 ITPR1 PRKD3 MAPK15 GRK2 MYLK3 ALPP

2.02e-052331469CID000003837
DrugCinnarizine

CACNA1F CACNA1S CACNA1G

2.11e-0591463DB00568
Drugguanosine 3',5'-cyclic monophosphoric acid

CACNA1B CACNA1F CACNA1S NPR3 PTGS1 RYR2 MYLK2 ITPR1 PRKD3 KCNA3 GRK2 FHOD1 CACNA1G HDAC2

2.16e-0557714614CID000000295
Drugtetraethylammonium

CACNA1S NPR3 PTGS1 PRKD3 KCNA3 GRK2 KCNA5 KCNQ4 ALPP

2.24e-052361469CID000005413
Drugarabinosyladenine

CACNA1B NPR3 GAL3ST4 PTGS1 RYR2 ITPR1 PRKD3 NLRP14 MAPK15 GRK2 MYLK3 GAL3ST3 ABCB11 ATP2A1 CTDSPL ALPP

3.21e-0576214616CID000000191
Drugmanidipine

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

3.41e-05951466CID000004008
Drughalothane

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 PRKD3 CACNA1G PLCG1 ATP2A1 ALPP

3.65e-0531414610CID000003562
DrugOxethazaine [126-27-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A

NPR3 PHLDA1 ITPR1 AP2S1 GRK2 TNNC2 KIF5C MMP3

3.72e-0519414684829_UP
Drugnitrendipine

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

4.07e-05981466CID000004507
DrugMibefradil

CACNA1F CACNA1S CACNA1G

4.10e-05111463DB01388
DrugAC1MBZ1C

CACNA1B NPR3 RAPGEF4 PTGS1 MYLK2 PRKD3 MAPK15 KCNA3 GRK2 MYLK3 ATP2A1

4.19e-0538714611CID000003541
DrugDantrolene-13C3

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G ATP2A1

4.26e-051451467CID000002951
Drugindo-1

ADGRV1 RYR2 ITPR1 PRKD3 TNNC2 ATP2A1

4.30e-05991466CID000105060
DrugC070379

CACNA1B RYR2 MYLK2 ITPR1 MAPK15 GRK2 KCNQ4 ATP2A1

4.45e-051991468CID003034747
Drugcobalt-60

CACNA1B HGD CACNA1F CACNA1S ACO1 RYR2 ITPR1 MIPEP CACNA1G MMP3 ALPP

4.49e-0539014611CID000061492
Drugrosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A

PCLO EPB41L5 RYR2 AP2S1 KLHL36 PLCG1 MMP3 CLEC16A

4.61e-0520014685230_DN
DrugBAPTA

CACNA1B CACNA1S RYR2 MYLK2 ITPR1 PRKD3 MAPK15 GRK2 PLCG1 ATP2A1

4.76e-0532414610CID000104751
Drugbarium

CACNA1B CACNA1S CAD PRKD3 KCNA3 KCNA5 CACNA1G

4.85e-051481467CID000104810
Drugaldosterone

CACNA1B CACNA1F CACNA1S NPR3 PTGS1 RYR2 ITPR1 PRKD3 CCNA1 CACNA1G MMP3

5.27e-0539714611CID000005839
Drugphosphine oxide

ACACA RYR2 PRKD3 GRK2 KCNA5 KCNQ4

6.66e-051071466CID000166931
DrugN-methyl-DL-aspartic acid

CACNA1B CACNA1F CACNA1S NPR3 ADGRV1 PTGS1 RYR2 ITPR1 PRKD3 NTNG2 MAPK15 GRK2 MYLK3 CACNA1G

8.50e-0565514614CID000004376
Drugnoradrealine

CACNA1B CACNA1F CACNA1S NPR3 ACACA RYR2 ITPR1 PRKD3 MAPK15 GRK2 CACNA1G PLCG1 MMP3

8.80e-0557514613CID000000951
Druggenistein

CACNA1B CACNA1F CACNA1S PTGS1 RYR2 MYLK2 TULP3 ITPR1 PRKD3 ERLIN2 MAPK15 GRK2 KCNA5 SLC12A4 CACNA1G PLCG1 MMP3 USP6NL ALPP

9.88e-05111714619CID005280961
DrugBarium

CACNA1B CACNA1F NPR3 SLC12A4 CACNA1G

1.00e-04721465ctd:D001464
Drugfelodipine

CACNA1B CACNA1F CACNA1S RYR2 MYLK2 ITPR1 CACNA1G

1.12e-041691467CID000003333
DrugNSC-351907

DDR1 MYLK2 PRKD3 ZP1 TRAP1 GRK2 TNNC2 PLCG1

1.19e-042291468CID000004016
DrugBumetanide

SLC12A6 PTGS1 SLC12A4

1.36e-04161463ctd:D002034
Drugcarbachol

CACNA1B CACNA1F CACNA1S NPR3 PTGS1 RYR2 MYLK2 ITPR1 PRKD3 MAPK15 GRK2 CACNA1G PLCG1 ATP2A1

1.42e-0468814614CID000002551
DrugClorocruoro Hem

RYR2 MYLK2 ITPR1 MAPK15 PLCG1 ATP2A1

1.44e-041231466CID003518809
DrugTMB-8

PTGS1 RYR2 ITPR1 PRKD3 CACNA1G MMP3 ATP2A1

1.44e-041761467CID000005494
DrugAC1L1B9H

PRKD3 KCNA3 GRK2 KCNA5 ABCB11

1.47e-04781465CID000001341
Drugpimozide

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 CACNA1G

1.71e-041271466CID000016362
DrugNSC7524

CACNA1B CACNA1F CACNA1S RYR2 ITPR1 SCN7A CACNA1G

1.77e-041821467CID000005657
Drugvalproate

CACNA1B CACNA1F CACNA1S ADGRV1 RYR2 ITPR1 MAPK15 KCNQ4 CACNA1G HDAC2

1.80e-0438114610CID000003121
DrugW7 hydrochloride

MYLK2 ITPR1 PRKD3 TRAP1 GRK2 MYLK3 KCNQ4 ATP2A1

2.16e-042501468CID000005681
Drugmyo-inositol

CACNA1B CACNA1F CACNA1S ACACA RYR2 MYLK2 TULP3 ITPR1 PRKD3 MAPK15 GRK2 CACNA1G PLCL1 PLCG1 ATP2A1

2.31e-0481114615CID000000892
DrugAC1MW7VF

HGD RYR2 EIF4G1

2.32e-04191463CID000414699
DrugAC1L380G

RYR2 TNNC2 ATP2A1

2.32e-04191463CID000084698
Diseaseepilepsy (implicated_via_orthology)

UNC13B SLC12A6 CACNA1B KCNA3 KCNA5 SLC12A4 SCN7A UNC13C UNC13A

1.15e-071631449DOID:1826 (implicated_via_orthology)
Diseasefourth ventricle volume measurement

CWF19L2 SCN7A MIPEP

6.08e-05161443EFO_0010303
Diseaseneurodegenerative disease (implicated_via_orthology)

TARDBP TOLLIP KIF5B KIF5C TRAK2 CLEC16A

8.11e-051451446DOID:1289 (implicated_via_orthology)
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1F CACNA1S

1.41e-0441442DOID:0060173 (implicated_via_orthology)
Diseasecholangiocarcinoma, sclerosing cholangitis

DOCK3 CABCOCO1

2.34e-0451442EFO_0004268, EFO_0005221
Diseaseasthma

DOCK3 HLA-DOB ACO1 CDHR3 NDUFS2 TRAP1 PLCL2 GAL3ST3 UNC13C PLCL1 FBXO45 CLEC16A

3.29e-0475114412MONDO_0004979
Diseasealcohol use disorder (implicated_via_orthology)

UNC13B NDUFS2 RYR2 UNC13C UNC13A HDAC2

4.04e-041951446DOID:1574 (implicated_via_orthology)
DiseaseBlastocyst Disintegration

PARG GRK2

4.89e-0471442C0012684
DiseaseEmbryo Loss

PARG GRK2

4.89e-0471442C0752351
DiseaseEmbryo Death

PARG GRK2

4.89e-0471442C0752350
DiseaseEmbryo Resorption

PARG GRK2

4.89e-0471442C0013937
Diseasefornix volume measurement

EVI5 PLCL1

4.89e-0471442EFO_0803381
DiseaseEmbryo Disintegration

PARG GRK2

4.89e-0471442C1136082
Diseasespinal muscular atrophy (implicated_via_orthology)

KIF5B KIF5C

8.33e-0491442DOID:12377 (implicated_via_orthology)
Diseaseegg allergy measurement

ABCB11 ITIH6

8.33e-0491442EFO_0007018
Diseasealopecia areata (is_marker_for)

KDM4A HDAC2

1.04e-03101442DOID:986 (is_marker_for)
Diseaseresponse to bisphosphonate, osteonecrosis

GTF2IRD1 NTNG2

1.04e-03101442EFO_0004259, EFO_0009958
Diseasehereditary spastic paraplegia (implicated_via_orthology)

ATL1 KIF5B KIF5C

1.22e-03431443DOID:2476 (implicated_via_orthology)
Diseasemotor neuron disease (implicated_via_orthology)

KIF5B KIF5C

1.51e-03121442DOID:231 (implicated_via_orthology)
DiseaseCongenital myopathy (disorder)

CACNA1S TNNC2

1.51e-03121442C0270960
DiseaseWeight Gain

NPR3 ME1 PRKD3 VPS13D

1.60e-031021444C0043094
DiseaseSpastic Paraplegia, Hereditary

ATL1 ERLIN2

2.07e-03141442C0037773
Diseaserenal cell carcinoma (biomarker_via_orthology)

CAD PTGS1

2.07e-03141442DOID:4450 (biomarker_via_orthology)
Diseaseeating disorder, bipolar disorder

RYR2 NALCN

2.07e-03141442EFO_0005203, MONDO_0004985
DiseaseCongestive heart failure

ACACA PTGS1 GRK2 ATP2A1

2.10e-031101444C0018802
DiseaseHeart failure

ACACA PTGS1 GRK2 ATP2A1

2.10e-031101444C0018801
DiseaseLeft-Sided Heart Failure

ACACA PTGS1 GRK2 ATP2A1

2.10e-031101444C0023212
DiseaseHeart Failure, Right-Sided

ACACA PTGS1 GRK2 ATP2A1

2.10e-031101444C0235527
DiseaseHeart Decompensation

ACACA PTGS1 GRK2 ATP2A1

2.10e-031101444C1961112
DiseaseMyocardial Failure

ACACA PTGS1 GRK2 ATP2A1

2.10e-031101444C1959583
Diseasebreast cancer (is_marker_for)

DDR1 PTGS1 MAPK15 KDM4A PLCG1

2.19e-031851445DOID:1612 (is_marker_for)
DiseasePeripheral Nervous System Diseases

SLC12A6 CACNA1B MMP3

2.35e-03541443C4721453
Diseaseamyotrophic lateral sclerosis, age at onset

IFRD1 KDM4A

2.38e-03151442EFO_0004847, MONDO_0004976
DiseaseProteinuria

CUBN UNC13C

2.38e-03151442HP_0000093
DiseaseN-acetylmethionine measurement

DOCK3 ITPR1

2.38e-03151442EFO_0021427
Diseaseclonal hematopoiesis mutation measurement

ITPR1 MIPEP OTUD3

2.48e-03551443EFO_0020949
Diseaseserum albumin measurement

DOCK3 EPB41L5 ADGRV1 TM6SF2 TARDBP ABCB9 MTM1 MIPEP RSBN1L

2.57e-035921449EFO_0004535
DiseaseHypertrophic Cardiomyopathy

RYR2 MYLK2 TNNC2

2.75e-03571443C0007194
Diseasethyroxine measurement, triiodothyronine measurement

GALNT13 ABCB9

3.07e-03171442EFO_0005130, EFO_0008392
DiseaseS-adenosylhomocysteine measurement

ANO4 CACNA1B

3.07e-03171442EFO_0010531
Diseaseglycochenodeoxycholate measurement

NTNG2 GRK2

3.07e-03171442EFO_0010490
Diseasecreatinine measurement

CACNA1S CCNP EPB41L5 LHX3 ADGRV1 CUBN NMRK2 TM6SF2 KIAA1755 PIP5K1A RSBN1L OPLAH

3.58e-0399514412EFO_0004518
DiseaseSchizophrenia

CACNA1B CACNA1F DDR1 BACE1 XRCC1 PTGS1 NTNG2 PLCL2 MMP3 FBXO45 HDAC2

4.12e-0388314411C0036341

Protein segments in the cluster

PeptideGeneStartEntry
ETAQEIVDEFAMRYG

UNC13A

856

Q9UPW8
IVDEFAMRYGVESIY

UNC13A

861

Q9UPW8
AVMRFDTDVELTYFL

ACO1

861

P21399
RVFDIFMYEGLEIVF

EVI5L

291

Q96CN4
FMYEGLEIVFRVGLA

EVI5L

296

Q96CN4
AVIMEGFYVVFDRAR

BACE1

396

P56817
IFQMFSGEDLLYEGE

ACY3

261

Q96HD9
EFMFYSAREEIVIGT

CABCOCO1

81

Q8IVU9
NFVIVYELLDELMDF

AP1M2

106

Q9Y6Q5
GYVEMEFEFDRLRAF

DDR1

266

Q08345
YTAFEVEEDVGLIMI

ADGRV1

4406

Q8WXG9
LIFGTMTDVFIDYDV

ABCB11

81

O95342
TFEDFVRIFDEVMGC

ACACA

1241

Q13085
DGVFMSFEGYNVEVR

GLCE

171

O94923
ISSDMFFGREVDAEY

ARFGAP2

431

Q8N6H7
FDAVVGYLEDIIMDD

ARL2BP

21

Q9Y2Y0
DEYLEMILQFGFTTI

ANO4

711

Q32M45
GEREYAGDIFAEVMV

CCNP

76

Q9H8S5
RERFEGFMDYSVPEI

DHX29

996

Q7Z478
LDYIFTGVFTFEMVI

CACNA1B

1186

Q00975
MVLDDSARFLEYETD

ATP2A1

576

O14983
EADMRFYAAEIILGL

GRK2

291

P25098
YTVVDEMFLAGEIRE

AP2S1

111

P53680
DRYGDFSVIAMTDVE

NPR3

411

P17342
YKATIGVDFEMERFE

RAB34

81

Q9BZG1
NYIDFFMEIDDIVRA

RAD17

456

O75943
GMIDEEFTVARLYIS

KIF5B

581

P33176
DRLVYMGFDALVAEA

NUB1

496

Q9Y5A7
DEYLEMVLQFGFVTI

ANO7

706

Q6IWH7
LDEYFSRVSELDIMF

AP4S1

91

Q9Y587
MEVIAEDNRFIYDGI

RSPH10B

601

P0C881
MEVIAEDNRFIYDGI

RSPH10B2

601

B2RC85
FVAVIMDNFDYLTRD

CACNA1F

1436

O60840
ESMERFDVLGVEAYS

KLHL36

506

Q8N4N3
VRGSEYDDFLDEFME

ME1

216

P48163
RVIFRMFDYTDDPEG

NCBP1

286

Q09161
TFTRGYRAMVLDVEF

ITPR1

2386

Q14643
IISFGEDEAGELYFM

HHIPL1

541

Q96JK4
FRMDEVVSQDFEGDY

KIAA1755

261

Q5JYT7
RDIYLVFEFMDTDLN

MAPK15

86

Q8TD08
FDDLMPEYVGFVRED

HSP90AB4P

316

Q58FF6
IFYSDEMFDLDVGSL

KATNIP

1136

O60303
RLYEGEADIMISFAV

MMP3

151

P08254
EFVMIVVFGLEYIVR

KCNQ4

136

P56696
VEYVVFDEADRLFEM

DDX54

241

Q8TDD1
TRGYDRDIAFIMDDF

PCLO

4411

Q9Y6V0
DVVYFTFGDSELMRD

PARG

896

Q86W56
TLVMEYVDGGELFDR

MYLK3

586

Q32MK0
VLFMEYIEGGELFER

MYLK2

356

Q9H1R3
FEDIVAERYGSMEIF

CWF19L2

251

Q2TBE0
FDIFMSEGLEIVFRV

EVI5

341

O60447
SEEIRFYQLGEEAME

KCNA3

181

P22001
FSERELAEVADEYMF

KDM4A

571

O75164
FEIITDTMVYFVGEN

PRKD3

486

O94806
ATGDEFYLMEDSRLV

LHX3

126

Q9UBR4
YISEMVIFFVVGFND

OR5B12

191

Q96R08
EEDISLTAYVVGMFF

OVOS2

1081

Q6IE36
SMLVDYGVEALVDAF

PTGS1

411

P23219
SVFDLVMVAEYFDES

GAL3ST4

296

Q96RP7
RDVLMQDFYVVESIF

PIP5K1A

106

Q99755
ERFAVDEYSDMVAVA

IQGAP3

1261

Q86VI3
EREKMFEFYERVSGA

NDUFS2

206

O75306
GVMIYFDRIEVVNFL

ERLIN2

81

O94905
FLAQLFMDTGYEEVV

METTL6

226

Q8TCB7
DYMIKQREDFEPFVE

OTUD3

101

Q5T2D3
IIDVISDDTFEYMAG

GALNT13

236

Q8IUC8
AYRALTETIMFDDAI

ALPP

346

P05187
MLVFVTDSDLAYEGF

CUBN

1021

O60494
VEEVFSLVMIAEYFD

GAL3ST3

231

Q96A11
LDLIESDYFGLRFMD

EPB41L5

76

Q9HCM4
LMEISEVDEGFYSRA

FAM126A

341

Q9BYI3
FADEIRFYQLGDEAM

KCNA5

196

P22460
QLFTEYGRLAMEETF

ATL1

191

Q8WXF7
EEYVRFDSDVGMFVA

HLA-DOB

61

P13765
EDTDVFFSLYDMREG

DOCK3

231

Q8IZD9
DFFIVIAGMLEYSLD

CACNA1G

156

O43497
EGLFTFQTREGEMIY

DOK6

206

Q6PKX4
FVAVIMDNFDYLTRD

CACNA1S

1376

Q13698
YRIIDGDGTDMFDIV

CDH10

306

Q9Y6N8
FFEGLSREDDVYSML

CTDSPL

256

O15194
MEDKTLAFERGYEFL

FBXO45

236

P0C2W1
YFEVVTTGMEQLDFE

CDHR3

81

Q6ZTQ4
MILGLEGRSVYEEDF

CUL3

191

Q13618
SVREGMAFEDVYEVD

CCNA1

151

P78396
LLRMFFDALYDEDVV

EIF4G1

1541

Q04637
LARGIESDFFYEDME

IFRD1

296

O00458
EEIVRFGFEVLYMDS

IFRD2

411

Q12894
FLVQYDVVMEDIIGD

ITIH6

246

Q6UXX5
FIDEEVEDMYLVDFT

CCDC174

101

Q6PII3
LSLEEQREMLEGFYE

FHOD1

86

Q9Y613
EIQMLARDFLDEYIF

DDX3Y

386

O15523
GDGVEEAFYTTDRVM

HDAC2

181

Q92769
MVEEVFDVLYSEALG

GTF2IRD1

131

Q9UHL9
LATELGTFFQEEEMY

H6PD

186

O95479
YMEFLEVLTEGLERV

SLC12A6

1121

Q9UHW9
EAEELFRMVAEVFIY

RYR2

3391

Q92736
LMLGEFVDDYTVRVI

PSMD14

56

O00487
FVDDYTVRVIDVFAM

PSMD14

61

O00487
MRFSIDVFEETRGYI

HGD

186

Q93099
GDTDVFLLVVMAYDR

OR4A8

106

P0C604
EVVYLDGMKSREELF

NMRK2

166

Q9NPI5
VELTDDVVMTFEYGR

NTNG2

131

Q96CW9
FSDEGMEVIERLIYL

NR6A1

361

Q15406
GLEMNYIVAEVEFRE

RSPH4A

361

Q5TD94
EMERFAEEFVGLVFS

RSBN1L

376

Q6PCB5
FLEEFYVSVSDDARM

RAPGEF4

601

Q8WZA2
ELREFFSQYGDVMDV

TARDBP

206

Q13148
VNGVIEEEFTMARLY

KIF5C

576

O60282
AFVERYMREFGFVIP

OPLAH

611

O14841
VEEAEELFRDMRFYG

KCNV2

226

Q8TDN2
MVRFVVLDDDYIGDE

PLCL2

826

Q9UPR0
DYMERQLDFTIGEAF

SI

1261

P14410
ELMYTTGEEVEVRDY

SUPV3L1

331

Q8IYB8
RVAVVEDFFDIIYSM

NOL4

101

O94818
YMEFLEVLTEGLERV

SLC12A4

1056

Q9UP95
VDIGFSIEELEDLYM

TBC1D9B

811

Q66K14
IAFIIYEFVLGDCME

ABCB9

446

Q9NP78
GEDIFLDMFEDEYRS

CLEC16A

606

Q2KHT3
EEEYLFMVGDFLLAV

CNGA4

241

Q8IV77
VLAEETFRYMILGTD

TRAK2

86

O60296
LAMIRFVVLDDDYIG

PLCL1

791

Q15111
DIYIFEGERVLTAMS

USP6NL

286

Q92738
FRDGYFVLVVSQEMA

ZP1

281

P60852
ASQEIVDEFAMRYGI

UNC13C

1401

Q8NB66
RVAELFMFDFEISGI

MIPEP

181

Q99797
LMLDSFYRSIEGFEI

MTM1

391

Q13496
YFTVVMAEGKEIDFR

PHLDA1

251

Q8WV24
YLEIFDERAFSMDDR

TOLLIP

116

Q9H0E2
DGAVIFYRDKTEELM

USP47

1311

Q96K76
FLRFVVYEEDMFSDQ

PLCG1

1156

P19174
MIVLFGLFVEYETDQ

RHAG

16

Q02094
TAQEIVDEFAMRYGI

UNC13B

781

O14795
IRVFGTSMVEEYEEI

SUCO

446

Q9UBS9
FDEISFEVVMDIYEL

CAD

991

P27708
IMVILFGVFVRYDFE

RHCG

21

Q9UBD6
AEARSYLSEEMIAEF

TNNC2

6

P02585
MARYEEVSVSGFEEF

TXNDC17

1

Q9BRA2
MEVVGDFEYSKRDLV

ULK2

1

Q8IYT8
FEDYGLFMREGIVTA

TRAP1

441

Q12931
GELEDYMSDRVQFVI

XRCC1

571

P18887
TVDIAISEEEEMFYG

SCN7A

876

Q01118
IALQEDSYVVGFMEF

TM6SF2

81

Q9BZW4
AMVATFFDIYEDGIL

ITFG1

396

Q8TB96
FGRFEEAERTYLEMD

WDR35

751

Q9P2L0
GTLFIYVLFMVEEFR

RNF145

426

Q96MT1
MEFVSGYRDEFLDFT

ZMYND15

1

Q9H091
LVMFEDVTVYFSREE

ZNF584

16

Q8IVC4
YIVMQFGRVADDVFT

TULP3

401

O75386
IGYFESVFVRMEDAA

VPS13D

1251

Q5THJ4
ELLGMSEDAREEYIY

NLRP14

326

Q86W24
RDFGGVMDIFIYLVS

NALCN

951

Q8IZF0