Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin filament binding	SHROOM3 MYO15A ADD3 CAMSAP3	5.14e-04	227	33	4	GO:0051015
GeneOntologyMolecularFunction	calmodulin binding	EWSR1 MYO15A ADD3 CAMSAP3	5.40e-04	230	33	4	GO:0005516
GeneOntologyMolecularFunction	transcription coregulator activity	KMT2C EWSR1 RERE BCL9 NIPBL	2.14e-03	562	33	5	GO:0003712
GeneOntologyCellularComponent	nuclear protein-containing complex	KMT2C TAF3 RERE SMG7 BCL9 NIPBL SUPT5H RNPC3 CAMSAP3	2.07e-04	1377	33	9	GO:0140513
Domain	PHD	KMT2C TAF3 PHF3	3.11e-04	75	33	3	PF00628
Domain	Znf_PHD-finger	KMT2C TAF3 PHF3	3.63e-04	79	33	3	IPR019787
Domain	PHD	KMT2C TAF3 PHF3	5.15e-04	89	33	3	SM00249
Domain	Znf_PHD	KMT2C TAF3 PHF3	5.49e-04	91	33	3	IPR001965
Domain	ZF_PHD_2	KMT2C TAF3 PHF3	6.23e-04	95	33	3	PS50016
Domain	ZF_PHD_1	KMT2C TAF3 PHF3	6.42e-04	96	33	3	PS01359
Domain	-	PABPC1L EWSR1 RNPC3 TMEM63A	8.63e-04	244	33	4	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	PABPC1L EWSR1 RNPC3 TMEM63A	1.06e-03	258	33	4	IPR012677
Domain	HMGI/Y_DNA-bd_CS	KMT2C EWSR1	1.36e-03	31	33	2	IPR000637
Domain	Znf_FYVE_PHD	KMT2C TAF3 PHF3	2.19e-03	147	33	3	IPR011011
Domain	SANT	CHD7 RERE	3.52e-03	50	33	2	SM00717
Domain	SANT/Myb	CHD7 RERE	3.80e-03	52	33	2	IPR001005
Domain	HMG_box	KMT2C SOX13	3.94e-03	53	33	2	PF00505
Domain	HMG	KMT2C SOX13	4.09e-03	54	33	2	SM00398
Domain	RRM_1	PABPC1L EWSR1 RNPC3	5.81e-03	208	33	3	PF00076
Domain	Zinc_finger_PHD-type_CS	TAF3 PHF3	5.87e-03	65	33	2	IPR019786
Domain	HMG_box_dom	KMT2C SOX13	5.87e-03	65	33	2	IPR009071
Domain	RRM	PABPC1L EWSR1 RNPC3	6.53e-03	217	33	3	SM00360
Pathway	REACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME	NCBP1 TAF3 SUPT5H	1.46e-04	70	21	3	M27008
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	NCBP1 TAF3 SUPT5H	2.26e-04	81	21	3	M865
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	NCBP1 TAF3 SUPT5H	2.42e-04	83	21	3	MM15314
Pathway	REACTOME_ABORTIVE_ELONGATION_OF_HIV_1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT	NCBP1 SUPT5H	5.25e-04	23	21	2	M3630
Pathway	REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS	CSN1S1 ADD3	6.21e-04	25	21	2	MM15172
Pathway	REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS	CSN1S1 ADD3	6.72e-04	26	21	2	M27424
Pathway	REACTOME_MRNA_CAPPING	NCBP1 SUPT5H	8.38e-04	29	21	2	M745
Pathway	REACTOME_MRNA_CAPPING	NCBP1 SUPT5H	8.38e-04	29	21	2	MM15409
Pathway	REACTOME_FORMATION_OF_THE_EARLY_ELONGATION_COMPLEX	NCBP1 SUPT5H	1.09e-03	33	21	2	MM14508
Pathway	REACTOME_FORMATION_OF_THE_EARLY_ELONGATION_COMPLEX	NCBP1 SUPT5H	1.09e-03	33	21	2	M26919
Pathway	REACTOME_HIV_LIFE_CYCLE	NCBP1 TAF3 SUPT5H	1.34e-03	149	21	3	M4076
Pathway	REACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX	BCL9 SOX13	1.76e-03	42	21	2	M27272
Pathway	REACTOME_HIV_TRANSCRIPTION_ELONGATION	NCBP1 SUPT5H	1.84e-03	43	21	2	M29569
Pathway	REACTOME_MRNA_SPLICING_MINOR_PATHWAY	NCBP1 RNPC3	2.29e-03	48	21	2	MM15410
Pathway	REACTOME_MRNA_SPLICING_MINOR_PATHWAY	NCBP1 RNPC3	2.48e-03	50	21	2	M5583
Pathway	REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX	NCBP1 SUPT5H	3.32e-03	58	21	2	M805
Pathway	REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX	NCBP1 SUPT5H	3.44e-03	59	21	2	MM14504
Pubmed	Interaction network of human early embryonic transcription factors.	KMT2C CHD7 TAF3 RERE BCL9 SOX13 NIPBL	3.42e-08	351	33	7	38297188
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	CHD7 TAF3 RERE BCL9 MN1 NIPBL PHF3 CAMSAP3	4.92e-07	774	33	8	15302935
Pubmed	Human transcription factor protein interaction networks.	KMT2C PABPC1L EWSR1 CHD7 TAF3 RERE SMG7 BCL9 SOX13 NIPBL	5.18e-07	1429	33	10	35140242
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KMT2C PARD3B CFAP20DC SHROOM3 RERE BCAR1 AADAT SMG7 TMEM63A CAMSAP3	7.54e-07	1489	33	10	28611215
Pubmed	Meis2 as a critical player in MN1-induced leukemia.	MN1 MEIS2	8.73e-07	2	33	2	28960191
Pubmed	Spinal cord astroblastoma with an EWSR1-BEND2 fusion classified as a high-grade neuroepithelial tumour with MN1 alteration.	EWSR1 MN1	2.62e-06	3	33	2	31863478
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CHD7 RERE BCL9 NIPBL PHF3	5.21e-06	268	33	5	33640491
Pubmed	CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression.	KMT2C ODAM	5.23e-06	4	33	2	38453924
Pubmed	Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins.	CSN1S1 ODAM	1.83e-05	7	33	2	13679022
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	EWSR1 SHROOM3 BCL9 ADD3	2.53e-05	180	33	4	35198878
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NCBP1 EWSR1 CHD7 NIPBL PHF3 SUPT5H	3.08e-05	653	33	6	22586326
Pubmed	Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers.	RERE BCAR1	3.13e-05	9	33	2	11782456
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	NCBP1 PABPC1L CTPS2 SMG7 C14orf119 SOX13 ADD3	4.48e-05	1038	33	7	26673895
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	NCBP1 EWSR1 CHD7 TAF3 NIPBL SUPT5H RNPC3	5.82e-05	1082	33	7	38697112
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	KMT2C CHD7 SMG7 PHF3	6.02e-05	225	33	4	12168954
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	CHD7 BCL9 NIPBL	6.79e-05	83	33	3	28794006
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	KMT2C PARD3B CHD7 TAF3 SUPT5H	7.59e-05	469	33	5	27634302
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	NCBP1 BCAR1 BCL9 NIPBL RNPC3 ADD3 DMXL1	1.20e-04	1215	33	7	15146197
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	PARD3B SHROOM3 BCAR1	1.25e-04	102	33	3	15778465
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KMT2C SHROOM3 CAMSAP3	1.29e-04	103	33	3	10819331
Pubmed	The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.	NCBP1 SMG7	1.32e-04	18	33	2	25220460
Pubmed	Does 3D Phenotyping Yield Substantial Insights in the Genetics of the Mouse Mandible Shape?	RERE MN1	1.32e-04	18	33	2	26921296
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PARD3B SHROOM3 BCAR1 PHF3 STARD9 CAMSAP3	1.42e-04	861	33	6	36931259
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	EWSR1 CHD7 PHF3 SUPT5H	1.46e-04	283	33	4	30585729
Pubmed	Meis2 Is Required for Inner Ear Formation and Proper Morphogenesis of the Cochlea.	CHD7 MEIS2	1.48e-04	19	33	2	34124068
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2C TAF3 SMG7 PHF3 ADD3	1.59e-04	549	33	5	38280479
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CHD7 BCAR1 SMG7 SOX13 SUPT5H	2.18e-04	588	33	5	38580884
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	NCBP1 EWSR1 CHD7 TAF3 PHF3 STARD9 ADD3	2.53e-04	1371	33	7	36244648
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	NCBP1 CHD7 TAF3 NIPBL PHF3	2.54e-04	608	33	5	36089195
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	EWSR1 SHROOM3 CHD7 BCL9 NIPBL CAMSAP3	2.59e-04	963	33	6	28671696
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	NCBP1 TAF3 MYO15A NIPBL PHF3 SUPT5H	3.42e-04	1014	33	6	32416067
Pubmed	AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay.	NCBP1 SMG7	3.49e-04	29	33	2	20371770
Pubmed	Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.	SHROOM3 ADD3	3.74e-04	30	33	2	29555813
Pubmed	The RNA polymerase II elongation complex.	NCBP1 SUPT5H	4.53e-04	33	33	2	12676794
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	KMT2C CHD7 MYO15A SUPT5H	5.32e-04	398	33	4	35016035
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	KMT2C EWSR1 CAMSAP3	5.34e-04	167	33	3	20362541
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	EWSR1 CHD7 MEIS2 TMEM63A	6.00e-04	411	33	4	35182466
Pubmed	Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.	EWSR1 PHF3 SUPT5H	6.32e-04	177	33	3	26206133
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SHROOM3 CHD7 BCAR1 BCL9	7.10e-04	430	33	4	35044719
Pubmed	Impact of WIN site inhibitor on the WDR5 interactome.	KMT2C RERE	7.69e-04	43	33	2	33472061
Pubmed	Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.	PABPC1L EWSR1 CHD7	8.62e-04	197	33	3	23686814
Pubmed	Congenital Diaphragmatic Hernia Overview	CHD7 NIPBL	8.80e-04	46	33	2	20301533
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	KMT2C EWSR1 SMG7 BCL9	8.90e-04	457	33	4	32344865
Interaction	HNF1B interactions	KMT2C EWSR1 CHD7 BCL9 SOX13 NIPBL	5.81e-07	190	33	6	int:HNF1B
Interaction	FEV interactions	KMT2C CHD7 TAF3 BCL9 SOX13 NIPBL	8.57e-07	203	33	6	int:FEV
Interaction	PAX9 interactions	KMT2C EWSR1 CHD7 BCL9 NIPBL	2.12e-06	130	33	5	int:PAX9
Interaction	SNRPC interactions	PARD3B NCBP1 EWSR1 RERE PHF3 SUPT5H ODAM	5.89e-06	440	33	7	int:SNRPC
Interaction	EGR2 interactions	KMT2C CHD7 RERE BCL9 NIPBL	8.12e-06	171	33	5	int:EGR2
Interaction	TLX1 interactions	KMT2C CHD7 BCL9 NIPBL MEIS2	9.09e-06	175	33	5	int:TLX1
Interaction	GSC interactions	KMT2C RERE BCL9 SOX13	1.20e-05	87	33	4	int:GSC
Interaction	PAX6 interactions	KMT2C CHD7 TAF3 BCL9 NIPBL MEIS2	2.52e-05	366	33	6	int:PAX6
Interaction	ERG interactions	KMT2C CHD7 RERE BCL9 NIPBL	2.92e-05	223	33	5	int:ERG
Interaction	PAX8 interactions	KMT2C CHD7 BCL9 NIPBL	3.15e-05	111	33	4	int:PAX8
Interaction	SNRPF interactions	PARD3B NCBP1 EWSR1 PHF3 SUPT5H RNPC3	3.35e-05	385	33	6	int:SNRPF
Interaction	TBXT interactions	KMT2C CHD7 BCL9 NIPBL	3.75e-05	116	33	4	int:TBXT
Interaction	CRX interactions	KMT2C CHD7 RERE BCL9 NIPBL	5.44e-05	254	33	5	int:CRX
Interaction	TLX2 interactions	KMT2C CHD7 BCL9 NIPBL	8.25e-05	142	33	4	int:TLX2
Interaction	TCF20 interactions	EWSR1 SMG7 SUPT5H CAMSAP3	9.19e-05	146	33	4	int:TCF20
Interaction	TLX3 interactions	KMT2C CHD7 RERE BCL9 NIPBL	1.03e-04	291	33	5	int:TLX3
Interaction	SP7 interactions	KMT2C CHD7 RERE BCL9 NIPBL	1.27e-04	304	33	5	int:SP7
Interaction	KMT2A interactions	KMT2C EWSR1 RERE SUPT5H MEIS2	1.48e-04	314	33	5	int:KMT2A
Interaction	SNRPB interactions	PARD3B NCBP1 EWSR1 PHF3 SUPT5H RNPC3	1.70e-04	517	33	6	int:SNRPB
Interaction	GCM1 interactions	KMT2C PABPC1L BCL9	1.86e-04	68	33	3	int:GCM1
Interaction	RPIA interactions	CTPS2 BCAR1 C14orf119	2.03e-04	70	33	3	int:RPIA
Interaction	FMR1 interactions	NCBP1 EWSR1 CHD7 SMG7 BCL9 NIPBL	2.07e-04	536	33	6	int:FMR1
Interaction	LHX3 interactions	KMT2C CHD7 BCL9 NIPBL	2.28e-04	185	33	4	int:LHX3
Interaction	SETD1B interactions	KMT2C RERE BCAR1	2.49e-04	75	33	3	int:SETD1B
Interaction	MYOD1 interactions	KMT2C TAF3 BCL9 NIPBL	2.74e-04	194	33	4	int:MYOD1
Interaction	PHIP interactions	TAF3 RERE BCAR1 SMG7	2.90e-04	197	33	4	int:PHIP
Interaction	GATA2 interactions	KMT2C CHD7 BCL9 NIPBL	3.02e-04	199	33	4	int:GATA2
Interaction	SOX7 interactions	KMT2C EWSR1 CHD7	3.24e-04	82	33	3	int:SOX7
Interaction	PAX2 interactions	KMT2C CHD7 BCL9	3.61e-04	85	33	3	int:PAX2
Interaction	IRF4 interactions	KMT2C CHD7 NIPBL	3.61e-04	85	33	3	int:IRF4
Interaction	BCL9 interactions	EWSR1 SMG7 BCL9	3.73e-04	86	33	3	int:BCL9
Interaction	KCNH1 interactions	BCAR1 STARD9	4.37e-04	19	33	2	int:KCNH1
Interaction	SUPT5H interactions	NCBP1 CHD7 NIPBL PHF3 SUPT5H	4.94e-04	408	33	5	int:SUPT5H
Interaction	SOX17 interactions	KMT2C CHD7 BCL9	5.00e-04	95	33	3	int:SOX17
Interaction	SOX9 interactions	KMT2C CHD7 BCL9	5.31e-04	97	33	3	int:SOX9
Interaction	NUP35 interactions	KMT2C EWSR1 BCAR1 SMG7 BCL9	5.88e-04	424	33	5	int:NUP35
Cytoband	4q21.1	SHROOM3 CSN1S1	3.28e-04	37	33	2	4q21.1
GeneFamily	PHD finger proteins	KMT2C TAF3 PHF3	7.71e-05	90	17	3	88
GeneFamily	RNA binding motif containing	PABPC1L EWSR1 RNPC3	9.70e-04	213	17	3	725
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	CHD7 RERE	1.11e-03	53	17	2	532
GeneFamily	PDZ domain containing	PARD3B SHROOM3	8.79e-03	152	17	2	1220
Coexpression	MYC_UP.V1_DN	IRGC BCAR1 BCL9 MN1	6.32e-05	172	33	4	M2708
Coexpression	GSE32901_TH1_VS_TH17_ENRICHED_CD4_TCELL_UP	PARD3B CHD7 ADD3 TMEM63A	6.60e-05	174	33	4	M8925
Coexpression	MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_22	EWSR1 MN1	8.39e-05	11	33	2	M11594
Coexpression	GSE29618_BCELL_VS_MDC_UP	CHD7 PHF3 ADD3 DMXL1	1.01e-04	194	33	4	M4943
Coexpression	GSE17721_PAM3CSK4_VS_CPG_16H_BMDC_UP	EWSR1 C14orf119 ADD3 TMEM63A	1.13e-04	200	33	4	M3869
Coexpression	LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE	PARD3B SHROOM3 RERE RNPC3	1.32e-04	208	33	4	M39233
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KMT2C CHD7 NIPBL MEIS2 ADD3	3.54e-07	200	33	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NCBP1 SHROOM3 SOX13 PHF3	4.27e-06	148	33	4	1d9fa6b2ee9feaed39c63d44e638b5c0942d947c
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	NCBP1 SHROOM3 SOX13 PHF3	4.50e-06	150	33	4	98fdc6bdfde84d680e11d8727502b79afbf64303
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAR1 SOX13 MEIS2 ADD3	1.03e-05	185	33	4	efcfbf5a48b3ea9a425183e5c2eec6a9585415a0
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAR1 SOX13 MEIS2 ADD3	1.03e-05	185	33	4	642088ace9230d38b0579853c54ff4dd8b5d5df4
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	PARD3B RERE NIPBL PHF3	1.19e-05	192	33	4	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	PARD3B RERE NIPBL PHF3	1.22e-05	193	33	4	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Epi-like\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PARD3B MYO15A CAMSAP3	1.57e-04	142	33	3	a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PARD3B MYO15A CAMSAP3	1.57e-04	142	33	3	d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MN1 STARD9 MEIS2	1.99e-04	154	33	3	e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-LMPP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SHROOM3 AADAT TMEM63A	2.23e-04	160	33	3	60fa1c717410aad7e8647703cb416cd7617cac29
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	CFAP20DC BCL9 SOX13	3.15e-04	180	33	3	81d60f0fa9e3b5bfcec85139a0a49e9130145f0e
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARD3B MEIS2 ADD3	3.15e-04	180	33	3	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARD3B MEIS2 ADD3	3.15e-04	180	33	3	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARD3B MEIS2 ADD3	3.20e-04	181	33	3	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MN1 STARD9 MEIS2	3.35e-04	184	33	3	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.41e-04	185	33	3	b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.52e-04	187	33	3	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.57e-04	188	33	3	505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRGC ADD3 DMXL1	3.57e-04	188	33	3	1f07e3ab87173426fe0c429f5c084fb3425effd3
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRGC ADD3 DMXL1	3.57e-04	188	33	3	85746f95319e494efdc1bbc24331698688d3a900
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MN1 SOX13 MEIS2	3.63e-04	189	33	3	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	droplet-Kidney-nan-21m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MN1 SOX13 MEIS2	3.63e-04	189	33	3	473c87036e04a058b4a5138438b7ba7e1e766799
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.63e-04	189	33	3	42ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.63e-04	189	33	3	784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCell	droplet-Kidney-nan-21m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MN1 SOX13 MEIS2	3.63e-04	189	33	3	2ce330d8078833c05775c481e73770f9ee4a5c88
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.63e-04	189	33	3	37ecbd73408d462b47d7e5611f203143e08a2689
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.68e-04	190	33	3	07f21386ea6eb23416a537d2250e3042efe93fb0
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MN1 SOX13 MEIS2	3.68e-04	190	33	3	5bf3d0beee69879c95265d07fba023626a7cc808
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MN1 SOX13 MEIS2	3.68e-04	190	33	3	cb8798839c27f307955fcc94a1ee40bca95b8e99
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.68e-04	190	33	3	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.68e-04	190	33	3	ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.74e-04	191	33	3	a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.74e-04	191	33	3	2b056cbe2e82e056e1f798974999378460eb1d16
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PARD3B CHD7 TMEM63A	3.74e-04	191	33	3	f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	PARD3B SHROOM3 RERE	3.80e-04	192	33	3	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NCBP1 CFAP20DC MEIS2	3.86e-04	193	33	3	088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PARD3B PABPC1L SHROOM3	3.86e-04	193	33	3	0ef076417ffe2dd1cbc2c3d1e35c7f8522af143b
ToppCell	facs-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2C NIPBL PHF3	3.92e-04	194	33	3	66c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	PARD3B MEIS2 ADD3	3.92e-04	194	33	3	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PARD3B SHROOM3 RERE	3.97e-04	195	33	3	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	PARD3B SHROOM3 RERE	4.03e-04	196	33	3	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PARD3B SHROOM3 RERE	4.03e-04	196	33	3	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MN1 PHF3 ADD3	4.03e-04	196	33	3	ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-PFC\|World / Primary Cells by Cluster	RERE MN1 MEIS2	4.09e-04	197	33	3	2c3b0072f8e1e09c77a85c6fc3133d1796932fb2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MN1 STARD9 MEIS2	4.09e-04	197	33	3	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-PFC-29\|World / Primary Cells by Cluster	RERE MN1 MEIS2	4.09e-04	197	33	3	c5bc0e7eb85642b270efc2ba92b13a736af22052
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MN1 STARD9 MEIS2	4.09e-04	197	33	3	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	PARD3B SHROOM3 RERE	4.16e-04	198	33	3	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	MN1 STARD9 MEIS2	4.16e-04	198	33	3	8689090bce9ab6e8f122426a404037e572c6713b
ToppCell	Non-neuronal-Dividing-Radial_Glia-vRG-20\|World / Primary Cells by Cluster	PARD3B SHROOM3 MEIS2	4.16e-04	198	33	3	bce0bc1e3f2257e0f42a1fa6e5b57cf71e4514ba
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	SHROOM3 TAF3 NIPBL	4.16e-04	198	33	3	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	KMT2C PARD3B RERE	4.22e-04	199	33	3	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	SHROOM3 NIPBL PHF3	4.22e-04	199	33	3	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	mild-B_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHD7 RERE DMXL1	4.28e-04	200	33	3	222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCell	Macroglial\|World / cells hierarchy compared to all cells using T-Statistic	PARD3B CHD7 TMEM63A	4.28e-04	200	33	3	e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2C NIPBL PHF3	4.28e-04	200	33	3	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	KMT2C NIPBL PHF3	4.28e-04	200	33	3	7dec470c379cd89f05a0f37c8628b21f136e52f0
Computational	Genes in the cancer module 237.	CHD7 RNPC3 ADD3 DMXL1	5.19e-06	58	22	4	MODULE_237
Drug	Acetaminophen [103-90-2]; Down 200; 26.4uM; MCF7; HT_HG-U133A	RERE SMG7 PHF3 SUPT5H TMEM63A	7.12e-06	194	32	5	5384_DN
Drug	Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; MCF7; HT_HG-U133A	RERE SMG7 BCL9 SOX13 PHF3	7.87e-06	198	32	5	3441_DN
Disease	hearing impairment	CHD7 MYO15A MN1	1.49e-04	98	31	3	C1384666
Disease	Tourette syndrome, schizophrenia	RERE PHF3	1.62e-04	18	31	2	EFO_0004895, MONDO_0005090
Disease	hemifacial microsomia	PARD3B SHROOM3	1.81e-04	19	31	2	MONDO_0015398
Disease	glomerular filtration rate, response to platinum based chemotherapy	RERE BCL9	3.97e-04	28	31	2	EFO_0004647, EFO_0005208
Disease	Congenital Heart Defects	NIPBL MEIS2	9.83e-04	44	31	2	C0018798
Disease	response to beta blocker	BCAR1 CAMSAP3	1.03e-03	45	31	2	EFO_0007766
Disease	neurofilament light chain measurement	MYO15A DMXL1	1.64e-03	57	31	2	EFO_0009178
Disease	granulocyte count	CHD7 RERE BCL9	2.37e-03	254	31	3	EFO_0007987
Disease	congenital heart disease (implicated_via_orthology)	KMT2C CHD7	2.40e-03	69	31	2	DOID:1682 (implicated_via_orthology)
Disease	Manic Disorder	STARD9 ADD3	2.54e-03	71	31	2	C0024713
Disease	Manic	STARD9 ADD3	3.05e-03	78	31	2	C0338831
Disease	Depression, Bipolar	STARD9 ADD3	3.13e-03	79	31	2	C0005587
Disease	thyroxine measurement	AADAT STARD9	3.45e-03	83	31	2	EFO_0005130
Disease	Prostatic Neoplasms	KMT2C EWSR1 CHD7 BCAR1	3.78e-03	616	31	4	C0033578
Disease	Malignant neoplasm of prostate	KMT2C EWSR1 CHD7 BCAR1	3.78e-03	616	31	4	C0376358
Disease	hypertrophic cardiomyopathy	KMT2C PARD3B	4.22e-03	92	31	2	EFO_0000538
Disease	Neurodevelopmental Disorders	KMT2C PARD3B	4.31e-03	93	31	2	C1535926
Disease	albuminuria	SHROOM3 CHD7	4.40e-03	94	31	2	EFO_0004285

Protein segments in the cluster

Peptide	Gene	Start	Entry
PSPVPEAPFQSEMYP	ATP6V1FNB	76	A0A1B0GUX0
MQPVTAPPSYPPTSY	EWSR1	181	Q01844
NPPTIHYPPSQGQMD	AADAT	96	Q8N5Z0
APAPPASQYTPMLPN	BCAR1	91	P56945
TTPPPPSMPHKERYF	ADD3	11	Q9UEY8
PVNHQMPYPPQDVVT	CBLL2	291	Q8N7E2
APVYMPHPETPSKPS	CAMSAP3	516	Q9P1Y5
MHPSQPQGTYASPPP	CHD7	381	Q9P2D1
TPYTHSNPGTPINMP	DMXL1	2711	Q9Y485
PSPPQHQRMPAYQET	PARD3B	1161	Q8TEW8
PMQPPPSSQDPYGSV	KMT2C	2046	Q8NEZ4
FTPPPHTEDSVYPMP	NCBP1	271	Q09161
PPIPSPHNPYAHAMD	MYO15A	416	Q9UKN7
SMAQPSYTPPQMTPH	MEIS2	401	O14770
MQYVPFPPFSDISNP	CSN1S1	156	P47710
FMPQQNSPVPSPYAP	NIPBL	166	Q6KC79
PPQTQPGPSHVMPYV	ODAM	116	A1E959
QQPSSYFLPAMPQPP	PABPC1L	401	Q4VXU2
AEAHMPPPFTPYVPR	TMEM63A	741	O94886
ETTMQPSPYPHPQFP	IRGC	91	Q6NXR0
TPYTMPPEPTLSQNP	BCL9	991	O00512
PHNTNPSPPLMSYIT	C14orf119	21	Q9NWQ9
PYSEPVFSMQHPPPQ	MN1	421	Q10571
TPSNMPPNFPYISSP	TAF3	481	Q5VWG9
PFPMEPYNHNPSEVK	SMG7	851	Q92540
PPPPSQETPVYSMDD	SHROOM3	1531	Q8TF72
YSMDDFPPPPPHTVC	SHROOM3	1541	Q8TF72
HPTPSPMAYQASPSP	SUPT5H	931	O00267
SPTNRNHPFYMPLNP	RERE	1266	Q9P2R6
KPATPPYPMPSTLSH	STARD9	3401	Q9P2P6
RHYQKEMNPPSPSNP	CFAP20DC	606	Q6ZVT6
HPEFSSRPMKPSPPY	CTPS2	526	Q9NRF8
YVMIPAFPPSHQPLP	SOX13	226	Q9UN79
DYMPLHAPLPPTSPQ	RNPC3	211	Q96LT9
PNFPPQSMFGFPPHL	PHF3	1821	Q92576