Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	ANO2 PACC1 GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	7.40e-10	193	48	9	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	ANO2 PACC1 GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	8.87e-10	197	48	9	GO:0022834
GeneOntologyMolecularFunction	gated channel activity	CACNA1F ANO2 PACC1 GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	5.58e-09	334	48	10	GO:0022836
GeneOntologyMolecularFunction	MAP kinase tyrosine phosphatase activity	DUSP1 DUSP2 DUSP4 DUSP9	6.11e-09	10	48	4	GO:0033550
GeneOntologyMolecularFunction	monoatomic ion channel activity	ATP5F1D CACNA1F ANO2 PACC1 GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	8.82e-09	459	48	11	GO:0005216
GeneOntologyMolecularFunction	protein tyrosine/threonine phosphatase activity	DUSP1 DUSP2 DUSP4 DUSP9	9.58e-09	11	48	4	GO:0008330
GeneOntologyMolecularFunction	MAP kinase tyrosine/serine/threonine phosphatase activity	DUSP1 DUSP2 DUSP4 DUSP9	2.07e-08	13	48	4	GO:0017017
GeneOntologyMolecularFunction	transporter activity	ATP5F1D SLC6A18 PITPNM3 SLC6A9 CACNA1F ANO2 PACC1 GRIN2B P2RX7 ATP8B2 CHRNA4 CHRNA5 CHRNB2 RYR3 GRAMD1A ITPR2	2.60e-08	1289	48	16	GO:0005215
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	ATP5F1D SLC6A18 SLC6A9 CACNA1F ANO2 PACC1 GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	2.95e-08	793	48	13	GO:0015075
GeneOntologyMolecularFunction	channel activity	ATP5F1D CACNA1F ANO2 PACC1 GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	3.50e-08	525	48	11	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	ATP5F1D CACNA1F ANO2 PACC1 GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	3.57e-08	526	48	11	GO:0022803
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	4.15e-08	140	48	7	GO:0099094
GeneOntologyMolecularFunction	excitatory extracellular ligand-gated monoatomic ion channel activity	GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2	5.82e-08	43	48	5	GO:0005231
GeneOntologyMolecularFunction	MAP kinase phosphatase activity	DUSP1 DUSP2 DUSP4 DUSP9	8.77e-08	18	48	4	GO:0033549
GeneOntologyMolecularFunction	monoatomic cation channel activity	ATP5F1D CACNA1F GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	1.09e-07	343	48	9	GO:0005261
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	ATP5F1D SLC6A18 SLC6A9 CACNA1F GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	3.73e-07	664	48	11	GO:0008324
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2	1.12e-06	77	48	5	GO:0005230
GeneOntologyMolecularFunction	transmembrane transporter activity	ATP5F1D SLC6A18 SLC6A9 CACNA1F ANO2 PACC1 GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	2.78e-06	1180	48	13	GO:0022857
GeneOntologyMolecularFunction	protein tyrosine/serine/threonine phosphatase activity	DUSP1 DUSP2 DUSP4 DUSP9	3.39e-06	43	48	4	GO:0008138
GeneOntologyMolecularFunction	acetylcholine binding	CHRNA4 CHRNA5 CHRNB2	3.67e-06	13	48	3	GO:0042166
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA4 CHRNA5 CHRNB2	8.66e-06	17	48	3	GO:0022848
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GRIN2B CHRNA4 CHRNA5 CHRNB2	1.06e-05	57	48	4	GO:1904315
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GRIN2B CHRNA4 CHRNA5 CHRNB2	1.30e-05	60	48	4	GO:0099529
GeneOntologyMolecularFunction	transmitter-gated channel activity	GRIN2B CHRNA4 CHRNA5 CHRNB2	1.79e-05	65	48	4	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	GRIN2B CHRNA4 CHRNA5 CHRNB2	1.79e-05	65	48	4	GO:0022824
GeneOntologyMolecularFunction	acetylcholine receptor activity	CHRNA4 CHRNA5 CHRNB2	2.23e-05	23	48	3	GO:0015464
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	GRIN2B CHRNA4 CHRNA5 CHRNB2	3.15e-05	75	48	4	GO:0098960
GeneOntologyMolecularFunction	myosin phosphatase activity	DUSP1 DUSP2 DUSP4 DUSP9	5.16e-05	85	48	4	GO:0017018
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	GRIN2B RYR3 ITPR2	5.59e-05	31	48	3	GO:0099604
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	ATP5F1D SLC6A18 SLC6A9 CACNA1F ANO2 PACC1 GRIN2B RYR3 ITPR2	6.93e-05	758	48	9	GO:0015318
GeneOntologyMolecularFunction	scaffold protein binding	GRIN2B P2RX7 CIT ITPR2	7.33e-05	93	48	4	GO:0097110
GeneOntologyMolecularFunction	neurotransmitter receptor activity	GRIN2B CHRNA4 CHRNA5 CHRNB2	9.73e-05	100	48	4	GO:0030594
GeneOntologyMolecularFunction	protein tyrosine phosphatase activity	DUSP1 DUSP2 DUSP4 DUSP9	1.09e-04	103	48	4	GO:0004725
GeneOntologyMolecularFunction	protein serine/threonine phosphatase activity	DUSP1 DUSP2 DUSP4 DUSP9	1.36e-04	109	48	4	GO:0004722
GeneOntologyMolecularFunction	calcium channel activity	CACNA1F GRIN2B RYR3 ITPR2	2.60e-04	129	48	4	GO:0005262
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1F GRIN2B RYR3 ITPR2	4.72e-04	151	48	4	GO:0015085
GeneOntologyMolecularFunction	phosphatase activity	G6PC2 DUSP1 DUSP2 DUSP4 DUSP9	6.12e-04	287	48	5	GO:0016791
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	ATP5F1D SLC6A18 SLC6A9 CACNA1F GRIN2B RYR3 ITPR2	7.00e-04	627	48	7	GO:0022890
GeneOntologyMolecularFunction	phospholipid transporter activity	PITPNM3 ANO2 ATP8B2	7.50e-04	74	48	3	GO:0005548
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC6A18 SLC6A9 CACNA1F GRIN2B RYR3 ITPR2	8.28e-04	465	48	6	GO:0046873
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH9 DNAH11	8.45e-04	18	48	2	GO:0008569
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR3 ITPR2	8.45e-04	18	48	2	GO:0015278
GeneOntologyMolecularFunction	phosphoprotein phosphatase activity	DUSP1 DUSP2 DUSP4 DUSP9	1.09e-03	189	48	4	GO:0004721
GeneOntologyMolecularFunction	lipid transporter activity	PITPNM3 ANO2 ATP8B2 GRAMD1A	1.25e-03	196	48	4	GO:0005319
GeneOntologyMolecularFunction	amino acid:sodium symporter activity	SLC6A18 SLC6A9	1.39e-03	23	48	2	GO:0005283
GeneOntologyMolecularFunction	calcium ion binding	PITPNM3 EFCAB10 FER1L5 CDH10 SVEP1 RYR3 ITPR2	1.96e-03	749	48	7	GO:0005509
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH9 DNAH11	2.06e-03	28	48	2	GO:0051959
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC6A18 SLC6A9 GRIN2B	2.06e-03	105	48	3	GO:0015171
GeneOntologyMolecularFunction	amino acid:monoatomic cation symporter activity	SLC6A18 SLC6A9	2.20e-03	29	48	2	GO:0005416
GeneOntologyMolecularFunction	phosphoric ester hydrolase activity	G6PC2 DUSP1 DUSP2 DUSP4 DUSP9	2.28e-03	386	48	5	GO:0042578
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	RYR3 ITPR2	2.85e-03	33	48	2	GO:0005217
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	PITPNM3 AARS1 G6PC2 DUSP1 DUSP2 DUSP4 DUSP9	2.98e-03	807	48	7	GO:0016788
GeneOntologyMolecularFunction	mitogen-activated protein kinase binding	DUSP1 DUSP2	3.20e-03	35	48	2	GO:0051019
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	SLC6A18 ANO2 PACC1	3.37e-03	125	48	3	GO:0015108
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH9 DNAH11	3.57e-03	37	48	2	GO:0045505
GeneOntologyMolecularFunction	neutral L-amino acid transmembrane transporter activity	SLC6A18 SLC6A9	4.37e-03	41	48	2	GO:0015175
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR52E4 OR10A7 GRIN2B P2RX7 OR10J1 CHRNA4 CHRNA5 CHRNB2 GPR75	4.45e-03	1353	48	9	GO:0004888
GeneOntologyMolecularFunction	quaternary ammonium group binding	CHRNA4 CHRNB2	5.47e-03	46	48	2	GO:0050997
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	SLC6A18 ANO2 PACC1	5.72e-03	151	48	3	GO:0008509
GeneOntologyMolecularFunction	ligand-gated monoatomic anion channel activity	ANO2 PACC1	6.44e-03	50	48	2	GO:0099095
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ANO2 ATP8B2	6.69e-03	51	48	2	GO:0140303
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC6A18 ANO2 PACC1	8.05e-03	171	48	3	GO:0015103
GeneOntologyMolecularFunction	lipid transfer activity	PITPNM3 GRAMD1A	8.30e-03	57	48	2	GO:0120013
GeneOntologyMolecularFunction	microtubule motor activity	DNAH9 DNAH11	1.23e-02	70	48	2	GO:0003777
GeneOntologyMolecularFunction	amino acid binding	AARS1 GRIN2B	1.33e-02	73	48	2	GO:0016597
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	ATP5F1D SLC6A18 SLC6A9 CACNA1F ANO2 PACC1 GRIN2B P2RX7 ATP8B2 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	1.44e-07	1115	48	14	GO:0034220
GeneOntologyBiologicalProcess	monoatomic ion transport	ATP5F1D SLC6A18 SLC6A9 CACNA1F ANO2 PACC1 FTH1P19 GRIN2B P2RX7 ATP8B2 CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	2.82e-07	1374	48	15	GO:0006811
GeneOntologyBiologicalProcess	presynaptic modulation of chemical synaptic transmission	P2RX7 ADCY1 CHRNA4 CHRNA5 CHRNB2	4.77e-07	67	48	5	GO:0099171
GeneOntologyBiologicalProcess	peptidyl-tyrosine dephosphorylation	DUSP1 DUSP2 DUSP4 DUSP9	1.14e-06	34	48	4	GO:0035335
GeneOntologyBiologicalProcess	behavioral response to nicotine	CHRNA4 CHRNA5 CHRNB2	1.93e-06	11	48	3	GO:0035095
GeneOntologyBiologicalProcess	sensory perception of pain	GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2	4.47e-06	105	48	5	GO:0019233
GeneOntologyBiologicalProcess	regulation of amine transport	GRIN2B P2RX7 PTGS1 CHRNA4 CHRNB2	1.05e-05	125	48	5	GO:0051952
GeneOntologyBiologicalProcess	excitatory postsynaptic potential	GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2	1.27e-05	130	48	5	GO:0060079
GeneOntologyBiologicalProcess	neuronal action potential	P2RX7 CHRNA4 CHRNA5 CHRNB2	1.39e-05	63	48	4	GO:0019228
GeneOntologyBiologicalProcess	amine transport	GRIN2B P2RX7 PTGS1 CHRNA4 CHRNB2	1.64e-05	137	48	5	GO:0015837
GeneOntologyBiologicalProcess	chemical synaptic transmission, postsynaptic	GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2	2.30e-05	147	48	5	GO:0099565
GeneOntologyBiologicalProcess	behavior	DERL2 GRIN2B CSMD1 ADCY1 PTGS1 CHRNA4 CHRNA5 CHRNB2 DNAH11 EIF4G1	3.16e-05	891	48	10	GO:0007610
GeneOntologyBiologicalProcess	cognition	GRIN2B CSMD1 ADCY1 PTGS1 CHRNA4 CHRNB2 DNAH11	5.17e-05	423	48	7	GO:0050890
GeneOntologyBiologicalProcess	monoatomic cation transport	ATP5F1D SLC6A18 SLC6A9 CACNA1F FTH1P19 GRIN2B P2RX7 CHRNA4 CHRNB2 RYR3 ITPR2	5.47e-05	1157	48	11	GO:0006812
GeneOntologyBiologicalProcess	regulation of postsynaptic membrane potential	GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2	6.05e-05	180	48	5	GO:0060078
GeneOntologyBiologicalProcess	memory	GRIN2B CSMD1 ADCY1 PTGS1 CHRNB2	6.54e-05	183	48	5	GO:0007613
GeneOntologyBiologicalProcess	response to alcohol	GRIN2B ADCY1 CHRNB2 GRAMD1A ITPR2 EIF4G1	8.21e-05	312	48	6	GO:0097305
GeneOntologyBiologicalProcess	metal ion transport	SLC6A18 SLC6A9 CACNA1F FTH1P19 GRIN2B P2RX7 CHRNA4 CHRNB2 RYR3 ITPR2	8.34e-05	1000	48	10	GO:0030001
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	ATP5F1D SLC6A18 SLC6A9 CACNA1F ANO2 PACC1 GRIN2B P2RX7 RYR3 ITPR2	9.60e-05	1017	48	10	GO:0098660
GeneOntologyBiologicalProcess	negative regulation of MAPK cascade	P2RX7 DUSP1 DUSP2 DUSP4 DUSP9	1.02e-04	201	48	5	GO:0043409
GeneOntologyBiologicalProcess	action potential	GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2	1.02e-04	201	48	5	GO:0001508
GeneOntologyBiologicalProcess	signal release	SLC6A9 G6PC2 P2RX7 CYP2J2 FER1L5 PTGS1 CHRNA4 CHRNB2	1.19e-04	653	48	8	GO:0023061
GeneOntologyBiologicalProcess	modulation of chemical synaptic transmission	SLC6A9 GRIN2B P2RX7 FER1L5 ADCY1 CHRNA4 CHRNA5 CHRNB2	1.32e-04	663	48	8	GO:0050804
GeneOntologyBiologicalProcess	transmission of nerve impulse	P2RX7 CHRNA4 CHRNA5 CHRNB2	1.33e-04	112	48	4	GO:0019226
GeneOntologyBiologicalProcess	regulation of trans-synaptic signaling	SLC6A9 GRIN2B P2RX7 FER1L5 ADCY1 CHRNA4 CHRNA5 CHRNB2	1.34e-04	664	48	8	GO:0099177
GeneOntologyBiologicalProcess	calcium ion transmembrane import into cytosol	CACNA1F GRIN2B P2RX7 RYR3 ITPR2	1.46e-04	217	48	5	GO:0097553
GeneOntologyBiologicalProcess	synaptic transmission, cholinergic	CHRNA4 CHRNA5 CHRNB2	1.46e-04	44	48	3	GO:0007271
GeneOntologyBiologicalProcess	calcium ion transport	CACNA1F GRIN2B P2RX7 CHRNA4 CHRNB2 RYR3 ITPR2	1.64e-04	509	48	7	GO:0006816
GeneOntologyBiologicalProcess	membrane depolarization	P2RX7 CHRNA4 CHRNA5 CHRNB2	1.80e-04	121	48	4	GO:0051899
GeneOntologyBiologicalProcess	endoderm formation	DUSP1 DUSP2 DUSP4	2.02e-04	49	48	3	GO:0001706
GeneOntologyBiologicalProcess	learning or memory	GRIN2B CSMD1 ADCY1 PTGS1 CHRNB2 DNAH11	2.17e-04	373	48	6	GO:0007611
GeneOntologyBiologicalProcess	acetylcholine receptor signaling pathway	CHRNA4 CHRNA5 CHRNB2	2.28e-04	51	48	3	GO:0095500
GeneOntologyBiologicalProcess	cellular response to acetylcholine	CHRNA4 CHRNA5 CHRNB2	2.55e-04	53	48	3	GO:1905145
GeneOntologyBiologicalProcess	regulation of secretion by cell	GRIN2B G6PC2 P2RX7 CYP2J2 FER1L5 PTGS1 CHRNA4 CHRNB2	2.80e-04	740	48	8	GO:1903530
GeneOntologyBiologicalProcess	response to acetylcholine	CHRNA4 CHRNA5 CHRNB2	3.01e-04	56	48	3	GO:1905144
GeneOntologyBiologicalProcess	response to nicotine	CHRNA4 CHRNA5 CHRNB2	3.34e-04	58	48	3	GO:0035094
GeneOntologyBiologicalProcess	positive regulation of amine transport	GRIN2B P2RX7 CHRNB2	3.34e-04	58	48	3	GO:0051954
GeneOntologyBiologicalProcess	regulation of secretion	GRIN2B G6PC2 P2RX7 CYP2J2 FER1L5 PTGS1 CHRNA4 CHRNB2	4.75e-04	801	48	8	GO:0051046
GeneOntologyBiologicalProcess	regulation of catecholamine secretion	PTGS1 CHRNA4 CHRNB2	5.10e-04	67	48	3	GO:0050433
GeneOntologyBiologicalProcess	response to ethanol	GRIN2B CHRNB2 ITPR2 EIF4G1	5.33e-04	161	48	4	GO:0045471
GeneOntologyBiologicalProcess	positive regulation of glutamate secretion	GRIN2B P2RX7	5.46e-04	15	48	2	GO:0014049
GeneOntologyBiologicalProcess	regulation of neuronal action potential	CHRNA5 CHRNB2	5.46e-04	15	48	2	GO:0098908
GeneOntologyBiologicalProcess	postsynaptic signal transduction	CHRNA4 CHRNA5 CHRNB2	5.56e-04	69	48	3	GO:0098926
GeneOntologyBiologicalProcess	secretion by cell	SLC6A9 GRIN2B G6PC2 P2RX7 CYP2J2 FER1L5 PTGS1 CHRNA4 CHRNB2	6.80e-04	1064	48	9	GO:0032940
GeneOntologyBiologicalProcess	sensory perception	OR52E4 CACNA1F OR10A7 GRIN2B P2RX7 OR10J1 CHRNA4 CHRNA5 CHRNB2	7.17e-04	1072	48	9	GO:0007600
GeneOntologyBiologicalProcess	catecholamine secretion	PTGS1 CHRNA4 CHRNB2	8.26e-04	79	48	3	GO:0050432
GeneOntologyBiologicalProcess	suckling behavior	DERL2 GRIN2B	8.84e-04	19	48	2	GO:0001967
GeneOntologyBiologicalProcess	cellular response to ATP	P2RX7 RYR3	1.08e-03	21	48	2	GO:0071318
GeneOntologyBiologicalProcess	amino acid transport	SLC6A18 SLC6A9 GRIN2B P2RX7	1.09e-03	195	48	4	GO:0006865
GeneOntologyBiologicalProcess	endoderm development	DUSP1 DUSP2 DUSP4	1.13e-03	88	48	3	GO:0007492
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	ATP5F1D SLC6A18 SLC6A9 CACNA1F GRIN2B P2RX7 RYR3 ITPR2	1.19e-03	922	48	8	GO:0098662
GeneOntologyBiologicalProcess	export from cell	SLC6A9 GRIN2B G6PC2 P2RX7 CYP2J2 FER1L5 PTGS1 CHRNA4 CHRNB2	1.20e-03	1153	48	9	GO:0140352
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	SLC6A9 GRIN2B P2RX7 FER1L5 ADCY1 CHRNA4 CHRNA5 CHRNB2	1.27e-03	931	48	8	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	SLC6A9 GRIN2B P2RX7 FER1L5 ADCY1 CHRNA4 CHRNA5 CHRNB2	1.27e-03	931	48	8	GO:0007268
GeneOntologyBiologicalProcess	trans-synaptic signaling	SLC6A9 GRIN2B P2RX7 FER1L5 ADCY1 CHRNA4 CHRNA5 CHRNB2	1.34e-03	939	48	8	GO:0099537
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	ATP5F1D SLC6A18 SLC6A9 CACNA1F GRIN2B P2RX7 RYR3 ITPR2	1.36e-03	942	48	8	GO:0098655
GeneOntologyBiologicalProcess	intracellular calcium ion homeostasis	CACNA1F GRIN2B P2RX7 RYR3 ITPR2	1.44e-03	359	48	5	GO:0006874
GeneOntologyBiologicalProcess	catecholamine transport	PTGS1 CHRNA4 CHRNB2	1.45e-03	96	48	3	GO:0051937
GeneOntologyBiologicalProcess	learning	GRIN2B CSMD1 PTGS1 CHRNB2	1.48e-03	212	48	4	GO:0007612
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception of pain	GRIN2B CHRNA5	1.66e-03	26	48	2	GO:0050966
GeneOntologyBiologicalProcess	cellular response to nitrogen compound	P2RX7 SGCB CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	1.67e-03	752	48	7	GO:1901699
GeneOntologyBiologicalProcess	synaptic signaling	SLC6A9 GRIN2B P2RX7 FER1L5 ADCY1 CHRNA4 CHRNA5 CHRNB2	1.71e-03	976	48	8	GO:0099536
GeneOntologyBiologicalProcess	secretion	SLC6A9 GRIN2B G6PC2 P2RX7 CYP2J2 FER1L5 PTGS1 CHRNA4 CHRNB2	1.79e-03	1221	48	9	GO:0046903
GeneOntologyBiologicalProcess	regulation of glutamate secretion	GRIN2B P2RX7	1.79e-03	27	48	2	GO:0014048
GeneOntologyBiologicalProcess	inhibitory postsynaptic potential	GRIN2B CHRNA4	1.79e-03	27	48	2	GO:0060080
GeneOntologyBiologicalProcess	regulation of transmission of nerve impulse	CHRNA5 CHRNB2	1.93e-03	28	48	2	GO:0051969
GeneOntologyBiologicalProcess	phospholipid transport	PITPNM3 P2RX7 ATP8B2	1.93e-03	106	48	3	GO:0015914
GeneOntologyBiologicalProcess	calcium ion homeostasis	CACNA1F GRIN2B P2RX7 RYR3 ITPR2	2.05e-03	389	48	5	GO:0055074
GeneOntologyBiologicalProcess	chemical homeostasis	CACNA1F FTH1P19 GRIN2B G6PC2 CSMD1 P2RX7 SGCB RYR3 ITPR2	2.09e-03	1249	48	9	GO:0048878
GeneOntologyBiologicalProcess	calcium ion transmembrane transport	CACNA1F GRIN2B P2RX7 RYR3 ITPR2	2.12e-03	392	48	5	GO:0070588
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR52E4 CACNA1F OR10A7 GRIN2B OR10J1 CHRNA5	2.21e-03	582	48	6	GO:0050906
GeneOntologyBiologicalProcess	negative regulation of intracellular signal transduction	P2RX7 CYP2J2 CIT DUSP1 DUSP2 DUSP4 DUSP9	2.28e-03	795	48	7	GO:1902532
GeneOntologyBiologicalProcess	response to nitrogen compound	DERL2 GRIN2B P2RX7 SGCB CHRNA4 CHRNA5 CHRNB2 RYR3 ITPR2	2.37e-03	1272	48	9	GO:1901698
GeneOntologyBiologicalProcess	monoamine transport	PTGS1 CHRNA4 CHRNB2	2.49e-03	116	48	3	GO:0015844
GeneOntologyCellularComponent	monoatomic ion channel complex	ATP5F1D CACNA1F ANO2 PACC1 GRIN2B CHRNA4 CHRNA5 CHRNB2 RYR3	1.69e-07	378	48	9	GO:0034702
GeneOntologyCellularComponent	transporter complex	ATP5F1D CACNA1F ANO2 PACC1 GRIN2B ATP8B2 CHRNA4 CHRNA5 CHRNB2 RYR3	3.90e-07	550	48	10	GO:1990351
GeneOntologyCellularComponent	transmembrane transporter complex	ATP5F1D CACNA1F ANO2 PACC1 GRIN2B CHRNA4 CHRNA5 CHRNB2 RYR3	2.52e-06	523	48	9	GO:1902495
GeneOntologyCellularComponent	acetylcholine-gated channel complex	CHRNA4 CHRNA5 CHRNB2	9.05e-06	18	48	3	GO:0005892
GeneOntologyCellularComponent	cholinergic synapse	CHRNA4 CHRNA5 CHRNB2	1.70e-05	22	48	3	GO:0098981
GeneOntologyCellularComponent	dopaminergic synapse	CHRNA4 CHRNA5 CHRNB2	1.70e-05	22	48	3	GO:0098691
GeneOntologyCellularComponent	presynapse	SLC6A9 ANO2 GRIN2B P2RX7 FER1L5 ADCY1 CDH10 CHRNA4 CHRNA5 CHRNB2	2.68e-05	886	48	10	GO:0098793
GeneOntologyCellularComponent	postsynaptic membrane	SLC6A9 GRIN2B ADCY1 CDH10 CHRNA4 CHRNA5 CHRNB2	3.61e-05	405	48	7	GO:0045211
GeneOntologyCellularComponent	presynaptic membrane	SLC6A9 ANO2 GRIN2B CDH10 CHRNA4 CHRNB2	3.94e-05	277	48	6	GO:0042734
GeneOntologyCellularComponent	synaptic membrane	SLC6A9 ANO2 GRIN2B ADCY1 CDH10 CHRNA4 CHRNA5 CHRNB2	4.92e-05	583	48	8	GO:0097060
GeneOntologyCellularComponent	postsynaptic specialization membrane	GRIN2B ADCY1 CDH10 CHRNA4 CHRNB2	9.57e-05	201	48	5	GO:0099634
GeneOntologyCellularComponent	postsynapse	SLC6A9 GRIN2B P2RX7 ADCY1 CDH10 CHRNA4 CHRNA5 CHRNB2 EIF4G1	4.48e-04	1018	48	9	GO:0098794
GeneOntologyCellularComponent	membrane protein complex	ATP5F1D CACNA1F ANO2 PACC1 GRIN2B SGCB CDH10 CHRNA4 CHRNA5 CHRNB2 RYR3	4.71e-04	1498	48	11	GO:0098796
GeneOntologyCellularComponent	hippocampal mossy fiber to CA3 synapse	SLC6A9 GRIN2B ADCY1	4.91e-04	67	48	3	GO:0098686
GeneOntologyCellularComponent	postsynaptic specialization	SLC6A9 GRIN2B ADCY1 CDH10 CHRNA4 CHRNB2	9.81e-04	503	48	6	GO:0099572
GeneOntologyCellularComponent	non-motile cilium	CACNA1F ANO2 ERICH3 PTGS1	1.06e-03	196	48	4	GO:0097730
GeneOntologyCellularComponent	plasma membrane protein complex	CACNA1F GRIN2B SGCB CDH10 CHRNA4 CHRNA5 CHRNB2	1.97e-03	785	48	7	GO:0098797
GeneOntologyCellularComponent	endoplasmic reticulum membrane	DERL2 GRIN2B G6PC2 CYP2J2 ATP8B2 PTGS1 RYR3 GRAMD1A ITPR2	2.42e-03	1293	48	9	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	DERL2 GRIN2B G6PC2 CYP2J2 ATP8B2 PTGS1 RYR3 GRAMD1A ITPR2	2.50e-03	1299	48	9	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	DERL2 GRIN2B G6PC2 CYP2J2 ATP8B2 PTGS1 RYR3 GRAMD1A ITPR2	2.88e-03	1327	48	9	GO:0042175
GeneOntologyCellularComponent	parallel fiber to Purkinje cell synapse	SLC6A9 GRIN2B	4.39e-03	43	48	2	GO:0098688
GeneOntologyCellularComponent	sarcoplasmic reticulum membrane	RYR3 ITPR2	4.80e-03	45	48	2	GO:0033017
GeneOntologyCellularComponent	cell body	PITPNM3 CACNA1F GRIN2B P2RX7 CIT CHRNA4 CHRNA5	5.02e-03	929	48	7	GO:0044297
GeneOntologyCellularComponent	dynein complex	DNAH9 DNAH11	6.85e-03	54	48	2	GO:0030286
MousePheno	abnormal behavioral response to nicotine	CHRNA4 CHRNB2	2.39e-05	3	40	2	MP:0020160
MousePheno	abnormal nicotine-mediated receptor currents	CHRNA4 CHRNB2	4.77e-05	4	40	2	MP:0009475
MousePheno	disorganized barrel cortex	GRIN2B ADCY1	7.94e-05	5	40	2	MP:0000861
MousePheno	abnormal pain threshold	SLC6A9 P2RX7 ADCY1 PTGS1 CHRNA4 CHRNB2	1.02e-04	267	40	6	MP:0001970
Domain	MKP	DUSP1 DUSP2 DUSP4 DUSP9	6.11e-09	10	45	4	IPR008343
Domain	RHOD	DUSP1 DUSP2 DUSP4 DUSP9	2.08e-07	22	45	4	SM00450
Domain	RHODANESE_3	DUSP1 DUSP2 DUSP4 DUSP9	2.52e-07	23	45	4	PS50206
Domain	Rhodanese-like_dom	DUSP1 DUSP2 DUSP4 DUSP9	3.02e-07	24	45	4	IPR001763
Domain	-	DUSP1 DUSP2 DUSP4 DUSP9	3.02e-07	24	45	4	3.40.250.10
Domain	Rhodanese	DUSP1 DUSP2 DUSP4 DUSP9	3.02e-07	24	45	4	PF00581
Domain	DUSP	DUSP1 DUSP2 DUSP4 DUSP9	8.82e-07	31	45	4	IPR024950
Domain	TYR_PHOSPHATASE_DUAL	DUSP1 DUSP2 DUSP4 DUSP9	1.29e-06	34	45	4	PS50054
Domain	DSPc	DUSP1 DUSP2 DUSP4 DUSP9	1.46e-06	35	45	4	SM00195
Domain	TYR_PHOSPHATASE_DUAL_dom	DUSP1 DUSP2 DUSP4 DUSP9	1.46e-06	35	45	4	IPR020422
Domain	Dual-sp_phosphatase_cat-dom	DUSP1 DUSP2 DUSP4 DUSP9	2.79e-06	41	45	4	IPR000340
Domain	DSPc	DUSP1 DUSP2 DUSP4 DUSP9	2.79e-06	41	45	4	PF00782
Domain	Nicotinic_acetylcholine_rcpt	CHRNA4 CHRNA5 CHRNB2	7.16e-06	16	45	3	IPR002394
Domain	Acetylcholine_rcpt_TM	CHRNA4 CHRNA5 CHRNB2	2.24e-05	23	45	3	IPR027361
Domain	-	CHRNA4 CHRNA5 CHRNB2	2.24e-05	23	45	3	1.20.120.370
Domain	TYR_PHOSPHATASE_1	DUSP1 DUSP2 DUSP4 DUSP9	5.41e-05	86	45	4	PS00383
Domain	TYR_PHOSPHATASE_2	DUSP1 DUSP2 DUSP4 DUSP9	5.66e-05	87	45	4	PS50056
Domain	TYR_PHOSPHATASE_dom	DUSP1 DUSP2 DUSP4 DUSP9	5.66e-05	87	45	4	IPR000387
Domain	-	DUSP1 DUSP2 DUSP4 DUSP9	7.04e-05	92	45	4	3.90.190.10
Domain	RIH_assoc	RYR3 ITPR2	8.46e-05	6	45	2	PF08454
Domain	RIH_assoc-dom	RYR3 ITPR2	8.46e-05	6	45	2	IPR013662
Domain	RYDR_ITPR	RYR3 ITPR2	8.46e-05	6	45	2	PF01365
Domain	RIH_dom	RYR3 ITPR2	8.46e-05	6	45	2	IPR000699
Domain	Ins145_P3_rcpt	RYR3 ITPR2	8.46e-05	6	45	2	IPR014821
Domain	Ryanodine_recept-rel	RYR3 ITPR2	8.46e-05	6	45	2	IPR015925
Domain	Ins145_P3_rec	RYR3 ITPR2	8.46e-05	6	45	2	PF08709
Domain	-	RYR3 ITPR2	8.46e-05	6	45	2	1.25.10.30
Domain	Prot-tyrosine_phosphatase-like	DUSP1 DUSP2 DUSP4 DUSP9	9.37e-05	99	45	4	IPR029021
Domain	Dynein_heavy_dom-1	DNAH9 DNAH11	1.57e-04	8	45	2	IPR013594
Domain	DHC_N1	DNAH9 DNAH11	1.57e-04	8	45	2	PF08385
Domain	Neurotransmitter_ion_chnl_CS	CHRNA4 CHRNA5 CHRNB2	1.73e-04	45	45	3	IPR018000
Domain	Neur_chan_memb	CHRNA4 CHRNA5 CHRNB2	1.85e-04	46	45	3	PF02932
Domain	Neur_chan_LBD	CHRNA4 CHRNA5 CHRNB2	1.97e-04	47	45	3	PF02931
Domain	Neur_channel	CHRNA4 CHRNA5 CHRNB2	1.97e-04	47	45	3	IPR006201
Domain	Neur_chan_lig-bd	CHRNA4 CHRNA5 CHRNB2	1.97e-04	47	45	3	IPR006202
Domain	NEUROTR_ION_CHANNEL	CHRNA4 CHRNA5 CHRNB2	1.97e-04	47	45	3	PS00236
Domain	Neurotrans-gated_channel_TM	CHRNA4 CHRNA5 CHRNB2	1.97e-04	47	45	3	IPR006029
Domain	-	CHRNA4 CHRNA5 CHRNB2	1.97e-04	47	45	3	2.70.170.10
Domain	MIR	RYR3 ITPR2	2.52e-04	10	45	2	PS50919
Domain	MIR	RYR3 ITPR2	2.52e-04	10	45	2	PF02815
Domain	MIR	RYR3 ITPR2	2.52e-04	10	45	2	SM00472
Domain	MIR_motif	RYR3 ITPR2	2.52e-04	10	45	2	IPR016093
Domain	PTPc_motif	DUSP1 DUSP2 DUSP4	3.87e-04	59	45	3	SM00404
Domain	Tyr_Pase_cat	DUSP1 DUSP2 DUSP4	3.87e-04	59	45	3	IPR003595
Domain	ATPase_dyneun-rel_AAA	DNAH9 DNAH11	5.07e-04	14	45	2	IPR011704
Domain	Dynein_heavy_chain_D4_dom	DNAH9 DNAH11	5.07e-04	14	45	2	IPR024317
Domain	Dynein_HC_stalk	DNAH9 DNAH11	5.07e-04	14	45	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH9 DNAH11	5.07e-04	14	45	2	IPR013602
Domain	DHC_N2	DNAH9 DNAH11	5.07e-04	14	45	2	PF08393
Domain	MT	DNAH9 DNAH11	5.07e-04	14	45	2	PF12777
Domain	AAA_8	DNAH9 DNAH11	5.07e-04	14	45	2	PF12780
Domain	AAA_5	DNAH9 DNAH11	5.07e-04	14	45	2	PF07728
Domain	DHC_fam	DNAH9 DNAH11	5.84e-04	15	45	2	IPR026983
Domain	Dynein_heavy_dom	DNAH9 DNAH11	5.84e-04	15	45	2	IPR004273
Domain	Dynein_heavy	DNAH9 DNAH11	5.84e-04	15	45	2	PF03028
Domain	Tyr_Pase_AS	DUSP1 DUSP2 DUSP4	7.23e-04	73	45	3	IPR016130
Domain	NA_NEUROTRAN_SYMP_2	SLC6A18 SLC6A9	8.47e-04	18	45	2	PS00754
Domain	NA_NEUROTRAN_SYMP_3	SLC6A18 SLC6A9	9.46e-04	19	45	2	PS50267
Domain	SNF	SLC6A18 SLC6A9	9.46e-04	19	45	2	PF00209
Domain	Na/ntran_symport	SLC6A18 SLC6A9	9.46e-04	19	45	2	IPR000175
Domain	NA_NEUROTRAN_SYMP_1	SLC6A18 SLC6A9	9.46e-04	19	45	2	PS00610
Domain	Ion_trans_dom	CACNA1F RYR3 ITPR2	2.61e-03	114	45	3	IPR005821
Domain	Ion_trans	CACNA1F RYR3 ITPR2	2.61e-03	114	45	3	PF00520
Domain	Sushi	CSMD1 SVEP1	6.97e-03	52	45	2	PF00084
Pathway	BIOCARTA_DSP_PATHWAY	DUSP1 DUSP2 DUSP4 DUSP9	6.24e-09	9	39	4	M22032
Pathway	BIOCARTA_DSP_PATHWAY	DUSP1 DUSP2 DUSP4 DUSP9	6.24e-09	9	39	4	MM1554
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP	DUSP1 DUSP2 DUSP4 DUSP9	2.35e-07	20	39	4	M47928
Pathway	REACTOME_RAF_INDEPENDENT_MAPK1_3_ACTIVATION	DUSP1 DUSP2 DUSP4 DUSP9	3.53e-07	22	39	4	MM14506
Pathway	REACTOME_RAF_INDEPENDENT_MAPK1_3_ACTIVATION	DUSP1 DUSP2 DUSP4 DUSP9	4.26e-07	23	39	4	M26917
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA4 CHRNA5 CHRNB2	1.63e-06	9	39	3	M27597
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA4 CHRNA5 CHRNB2	1.63e-06	9	39	3	MM15313
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA4 CHRNA5 CHRNB2	3.18e-06	11	39	3	M883
Pathway	REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA4 CHRNA5 CHRNB2	4.23e-06	12	39	3	M48008
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA4 CHRNA5 CHRNB2	4.23e-06	12	39	3	MM15312
Pathway	REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY	DUSP1 DUSP2 DUSP4 DUSP9	5.19e-06	42	39	4	MM15274
Pathway	REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY	DUSP1 DUSP2 DUSP4 DUSP9	5.71e-06	43	39	4	M27560
Pathway	REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS	CHRNA4 CHRNA5 CHRNB2	6.98e-06	14	39	3	M757
Pathway	REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS	CHRNA4 CHRNA5 CHRNB2	8.71e-06	15	39	3	MM14704
Pathway	WP_NICOTINE_EFFECT_ON_DOPAMINERGIC_NEURONS	CHRNA4 CHRNA5 CHRNB2	2.52e-05	21	39	3	M39343
Pathway	WP_ALZHEIMERS_DISEASE	CACNA1F GRIN2B RYR3 ITPR2	5.01e-05	74	39	4	MM15962
Pathway	KEGG_MEDICUS_ENV_FACTOR_NICOTINE_TO_JAK_STAT_SIGNALING_PATHWAY	CHRNA4 CHRNB2	7.42e-05	5	39	2	M48978
Pathway	KEGG_ALZHEIMERS_DISEASE	ATP5F1D CACNA1F GRIN2B RYR3 ITPR2	8.88e-05	166	39	5	M16024
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	CACNA1F P2RX7 ADCY1 RYR3 ITPR2	1.23e-04	178	39	5	M2890
Pathway	REACTOME_HIGHLY_SODIUM_PERMEABLE_POSTSYNAPTIC_ACETYLCHOLINE_NICOTINIC_RECEPTORS	CHRNA4 CHRNB2	1.55e-04	7	39	2	M27596
Pathway	REACTOME_HIGHLY_SODIUM_PERMEABLE_POSTSYNAPTIC_ACETYLCHOLINE_NICOTINIC_RECEPTORS	CHRNA4 CHRNB2	1.55e-04	7	39	2	MM15311
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	GRIN2B ADCY1 CHRNA4 CHRNA5 CHRNB2	2.39e-04	205	39	5	M752
Pathway	REACTOME_MAPK_FAMILY_SIGNALING_CASCADES	RAG2 GRIN2B DUSP1 DUSP2 DUSP4 DUSP9	2.54e-04	327	39	6	M27565
Pathway	WP_MAPK_SIGNALING	CACNA1F DUSP1 DUSP2 DUSP4 DUSP9	5.51e-04	246	39	5	M39597
Pathway	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	P2RX7 ITPR2	5.71e-04	13	39	2	MM14553
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	ADCY1 CHRNA4 CHRNA5 CHRNB2	6.51e-04	144	39	4	MM14501
Pathway	KEGG_MAPK_SIGNALING_PATHWAY	CACNA1F DUSP1 DUSP2 DUSP4 DUSP9	7.98e-04	267	39	5	M10792
Pathway	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	GRIN2B ADCY1 CHRNA4 CHRNA5 CHRNB2	8.39e-04	270	39	5	M15514
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	GRIN2B P2RX7 CHRNA4 CHRNA5 CHRNB2	8.68e-04	272	39	5	M13380
Pathway	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	P2RX7 ITPR2	8.73e-04	16	39	2	M26945
Pathway	KEGG_LONG_TERM_POTENTIATION	GRIN2B ADCY1 ITPR2	9.43e-04	70	39	3	M3115
Pathway	KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_RAS_ERK_SIGNALING_PATHWAY	CHRNA4 CHRNB2	1.24e-03	19	39	2	M47793
Pathway	REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS	SLC6A18 SLC6A9	1.24e-03	19	39	2	M27362
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	RYR3 ITPR2	1.24e-03	19	39	2	M47760
Pathway	REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS	SLC6A18 SLC6A9	1.24e-03	19	39	2	MM15107
Pathway	BIOCARTA_EICOSANOID_PATHWAY	CYP2J2 PTGS1	1.66e-03	22	39	2	M22003
Pathway	KEGG_DILATED_CARDIOMYOPATHY	CACNA1F SGCB ADCY1	1.95e-03	90	39	3	M835
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	P2RX7 ITPR2	2.51e-03	27	39	2	MM15053
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH9 DNAH11	2.51e-03	27	39	2	M47755
Pathway	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	ADCY1 CHRNA4 CHRNA5 CHRNB2	2.66e-03	211	39	4	MM14502
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	P2RX7 ITPR2	2.69e-03	28	39	2	M924
Pathway	KEGG_GNRH_SIGNALING_PATHWAY	CACNA1F ADCY1 ITPR2	2.71e-03	101	39	3	M1979
Pubmed	Acetylcholine-stimulated [3H]GABA release from mouse brain synaptosomes is modulated by alpha4beta2 and alpha4alpha5beta2 nicotinic receptor subtypes.	CHRNA4 CHRNA5 CHRNB2	2.47e-09	3	48	3	19139153
Pubmed	Acetylcholine receptor (AChR) α5 subunit variant associated with risk for nicotine dependence and lung cancer reduces (α4β2)₂α5 AChR function.	CHRNA4 CHRNA5 CHRNB2	2.47e-09	3	48	3	20881005
Pubmed	Probing the non-canonical interface for agonist interaction with an α5 containing nicotinic acetylcholine receptor.	CHRNA4 CHRNA5 CHRNB2	2.47e-09	3	48	3	24144909
Pubmed	Unorthodox Acetylcholine Binding Sites Formed by α5 and β3 Accessory Subunits in α4β2* Nicotinic Acetylcholine Receptors.	CHRNA4 CHRNA5 CHRNB2	9.86e-09	4	48	3	27645992
Pubmed	Selectivity of ABT-089 for alpha4beta2* and alpha6beta2* nicotinic acetylcholine receptors in brain.	CHRNA4 CHRNA5 CHRNB2	9.86e-09	4	48	3	19481067
Pubmed	Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence.	CHRNA4 CHRNA5 CHRNB2	9.86e-09	4	48	3	19482438
Pubmed	Low ethanol concentration alters CHRNA5 RNA levels during early human development.	CHRNA4 CHRNA5 CHRNB2	2.46e-08	5	48	3	20438829
Pubmed	Epidermal growth factor receptor and protein kinase C signaling to ERK2: spatiotemporal regulation of ERK2 by dual specificity phosphatases.	DUSP1 DUSP2 DUSP4	2.46e-08	5	48	3	18178562
Pubmed	α4β2 nicotinic acetylcholine receptors in the early postnatal mouse superior cervical ganglion.	CHRNA4 CHRNA5 CHRNB2	4.92e-08	6	48	3	21485013
Pubmed	Distribution of neuronal nicotinic acetylcholine receptor gene restriction fragment length polymorphisms in inbred and partially inbred mice.	CHRNA4 CHRNA5 CHRNB2	8.60e-08	7	48	3	8563774
Pubmed	Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32.	CHRNA4 CHRNA5 CHRNB2	8.60e-08	7	48	3	9009220
Pubmed	Chromosomal localization of seven neuronal nicotinic acetylcholine receptor subunit genes in humans.	CHRNA4 CHRNA5 CHRNB2	8.60e-08	7	48	3	1505988
Pubmed	Dissection of behavior and psychiatric disorders using the mouse as a model.	GRIN2B ADCY1 CHRNB2 RYR3	9.77e-08	31	48	4	10767319
Pubmed	Why do young women smoke? V. Role of direct and interactive effects of nicotinic cholinergic receptor gene variation on neurocognitive function.	CHRNA4 CHRNA5 CHRNB2	1.37e-07	8	48	3	17559419
Pubmed	Functional interaction between Lypd6 and nicotinic acetylcholine receptors.	CHRNA4 CHRNA5 CHRNB2	1.37e-07	8	48	3	27344019
Pubmed	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.	CHRNA4 CHRNA5 CHRNB2	2.06e-07	9	48	3	8906617
Pubmed	Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release.	CHRNA4 CHRNA5 CHRNB2	2.06e-07	9	48	3	19228980
Pubmed	Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence.	CHRNA4 CHRNA5 CHRNB2	2.94e-07	10	48	3	20736995
Pubmed	Differential expression of nicotinic acetylcholine receptor subunits in fetal and neonatal mouse thymus.	CHRNA4 CHRNA5 CHRNB2	4.04e-07	11	48	3	12225896
Pubmed	Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.	GRIN2B ADCY1 CHRNA4 CHRNA5 CHRNB2	6.29e-07	118	48	5	19156168
Pubmed	Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development.	CHRNA4 CHRNA5 CHRNB2	8.88e-07	14	48	3	23213462
Pubmed	Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties.	CHRNA4 CHRNA5 CHRNB2	8.88e-07	14	48	3	19059502
Pubmed	Analysis of nicotinic acetylcholine receptor subunits in the cochlea of the mouse.	CHRNA4 CHRNA5 CHRNB2	1.11e-06	15	48	3	8838678
Pubmed	Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.	CHRNA4 CHRNA5 CHRNB2	1.36e-06	16	48	3	19259974
Pubmed	Reduced antinociception in mice lacking neuronal nicotinic receptor subunits.	CHRNA4 CHRNB2	1.87e-06	2	48	2	10235262
Pubmed	Evaluation of the Nicotinic Acetylcholine Receptor-Associated Proteome at Baseline and Following Nicotine Exposure in Human and Mouse Cortex.	CHRNA4 CHRNB2	1.87e-06	2	48	2	27559543
Pubmed	X-ray structure of the human α4β2 nicotinic receptor.	CHRNA4 CHRNB2	1.87e-06	2	48	2	27698419
Pubmed	Dendritic spine density of prefrontal layer 6 pyramidal neurons in relation to apical dendrite sculpting by nicotinic acetylcholine receptors.	CHRNA4 CHRNA5	1.87e-06	2	48	2	26500498
Pubmed	[(3)H]Epibatidine photolabels non-equivalent amino acids in the agonist binding site of Torpedo and alpha4beta2 nicotinic acetylcholine receptors.	CHRNA4 CHRNB2	1.87e-06	2	48	2	19620239
Pubmed	Extracellular domain nicotinic acetylcholine receptors formed by alpha4 and beta2 subunits.	CHRNA4 CHRNB2	1.87e-06	2	48	2	16174636
Pubmed	Properties of mutated murine alpha4beta2 nicotinic receptors linked to partial epilepsy.	CHRNA4 CHRNB2	1.87e-06	2	48	2	18321647
Pubmed	Whole Genome Microarray Analysis of DUSP4-Deletion Reveals A Novel Role for MAP Kinase Phosphatase-2 (MKP-2) in Macrophage Gene Expression and Function.	DUSP4 DUSP9	1.87e-06	2	48	2	31336892
Pubmed	Phenotypic comparison of two Scottish families with mutations in different genes causing autosomal dominant nocturnal frontal lobe epilepsy.	CHRNA4 CHRNB2	1.87e-06	2	48	2	12681012
Pubmed	The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity alpha 4 beta 2 nAChRs.	CHRNA4 CHRNB2	1.87e-06	2	48	2	12871652
Pubmed	Post-translational regulation of mitogen-activated protein kinase phosphatase (MKP)-1 and MKP-2 in macrophages following lipopolysaccharide stimulation: the role of the C termini of the phosphatases in determining their stability.	DUSP1 DUSP4	1.87e-06	2	48	2	25204653
Pubmed	Assembly of human neuronal nicotinic receptor alpha5 subunits with alpha3, beta2, and beta4 subunits.	CHRNA5 CHRNB2	1.87e-06	2	48	2	8663494
Pubmed	Functional characterization of mouse alpha4beta2 nicotinic acetylcholine receptors stably expressed in HEK293T cells.	CHRNA4 CHRNB2	1.87e-06	2	48	2	15569257
Pubmed	α4β2 nicotinic acetylcholine receptors intrinsically influence body weight in mice.	CHRNA4 CHRNB2	1.87e-06	2	48	2	31881170
Pubmed	An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors.	CHRNA4 CHRNB2	1.87e-06	2	48	2	25869137
Pubmed	Requirement of nicotinic acetylcholine receptor subunit beta2 in the maintenance of spiral ganglion neurons during aging.	CHRNA5 CHRNB2	1.87e-06	2	48	2	15788760
Pubmed	Antibodies against extracellular domains of α4 and α7 subunits alter the levels of nicotinic receptors in the mouse brain and affect memory: possible relevance to Alzheimer's pathology.	CHRNA4 CHRNA5	1.87e-06	2	48	2	21321393
Pubmed	Unraveling amino acid residues critical for allosteric potentiation of (α4)3(β2)2-type nicotinic acetylcholine receptor responses.	CHRNA4 CHRNB2	1.87e-06	2	48	2	28446611
Pubmed	Inhibited Expression of α4β2 Nicotinic Acetylcholine Receptor in Blood Leukocytes of Chinese Patients with Vascular Dementia and in Blood Leukocytes as Well as the Hippocampus of Brain from Ischemic Rats.	CHRNA4 CHRNB2	1.87e-06	2	48	2	26858154
Pubmed	The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental area.	CHRNA4 CHRNA5	1.87e-06	2	48	2	23869214
Pubmed	Identification of the Initial Steps in Signal Transduction in the α4β2 Nicotinic Receptor: Insights from Equilibrium and Nonequilibrium Simulations.	CHRNA4 CHRNB2	1.87e-06	2	48	2	31130483
Pubmed	Plasticity of prefrontal attention circuitry: upregulated muscarinic excitability in response to decreased nicotinic signaling following deletion of α5 or β2 subunits.	CHRNA5 CHRNB2	1.87e-06	2	48	2	22072695
Pubmed	[Molecular and genetic basis of idiopathic nocturnal frontal lobe epilepsy].	CHRNA4 CHRNB2	1.87e-06	2	48	2	12185808
Pubmed	Contribution of α4β2 nAChR in nicotine-induced intracellular calcium response and excitability of MSDB neurons.	CHRNA4 CHRNB2	1.87e-06	2	48	2	25451094
Pubmed	A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men.	CHRNA4 CHRNB2	1.87e-06	2	48	2	15154117
Pubmed	Purinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: roles in the outcome of excitotoxic brain injury.	P2RX7 PTGS1	1.87e-06	2	48	2	22022466
Pubmed	Tonic nicotinic modulation of serotoninergic transmission in the spinal cord.	CHRNA4 CHRNB2	1.87e-06	2	48	2	11226321
Pubmed	Association of alpha4beta2 nicotinic receptor and heavy smoking in schizophrenia.	CHRNA4 CHRNB2	1.87e-06	2	48	2	18043764
Pubmed	A portable site: a binding element for 17β-estradiol can be placed on any subunit of a nicotinic α4β2 receptor.	CHRNA4 CHRNB2	1.87e-06	2	48	2	21451042
Pubmed	Sustained saturating level of glycine induces changes in NR2B-containing-NMDA receptor localization in the CA1 region of the hippocampus.	SLC6A9 GRIN2B	1.87e-06	2	48	2	18331477
Pubmed	Variants in CHRNB2 and CHRNA4 Identified in Patients with Insular Epilepsy.	CHRNA4 CHRNB2	1.87e-06	2	48	2	32536355
Pubmed	Differential α4(+)/(-)β2 Agonist-binding Site Contributions to α4β2 Nicotinic Acetylcholine Receptor Function within and between Isoforms.	CHRNA4 CHRNB2	1.87e-06	2	48	2	26644472
Pubmed	The E Loop of the Transmitter Binding Site Is a Key Determinant of the Modulatory Effects of Physostigmine on Neuronal Nicotinic α4β2 Receptors.	CHRNA4 CHRNB2	1.87e-06	2	48	2	27895161
Pubmed	Serine residues in the α4 nicotinic acetylcholine receptor subunit regulate surface α4β2* receptor expression and clustering.	CHRNA4 CHRNB2	1.87e-06	2	48	2	30414940
Pubmed	The nicotine metabolite, cotinine, alters the assembly and trafficking of a subset of nicotinic acetylcholine receptors.	CHRNA4 CHRNB2	1.87e-06	2	48	2	26269589
Pubmed	Organelle-specific single-molecule imaging of α4β2 nicotinic receptors reveals the effect of nicotine on receptor assembly and cell-surface trafficking.	CHRNA4 CHRNB2	1.87e-06	2	48	2	29074617
Pubmed	Chronic nicotine alters nicotinic receptor-induced presynaptic Ca2+ responses in isolated nerve terminals.	CHRNA4 CHRNB2	1.87e-06	2	48	2	18095155
Pubmed	Promoted neuronal differentiation after activation of alpha4/beta2 nicotinic acetylcholine receptors in undifferentiated neural progenitors.	CHRNA4 CHRNB2	1.87e-06	2	48	2	23056257
Pubmed	Nicotinic acetylcholine receptor subunits α4 and α5 associated with smoking behaviour and lung cancer are regulated by upstream open reading frames.	CHRNA4 CHRNA5	1.87e-06	2	48	2	23843950
Pubmed	Genetic interaction between alpha4 and beta2 subunits of high affinity nicotinic receptor: analysis in schizophrenia.	CHRNA4 CHRNB2	1.87e-06	2	48	2	16636791
Pubmed	Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity.	DUSP1 DUSP4	1.87e-06	2	48	2	24658355
Pubmed	Association of the neuronal nicotinic receptor beta2 subunit gene (CHRNB2) with subjective responses to alcohol and nicotine.	CHRNA4 CHRNB2	1.87e-06	2	48	2	17226798
Pubmed	Treatment for tobacco dependence: effect on brain nicotinic acetylcholine receptor density.	CHRNA4 CHRNB2	1.87e-06	2	48	2	23429692
Pubmed	Brain nicotinic acetylcholine receptor availability and response to smoking cessation treatment: a randomized trial.	CHRNA4 CHRNB2	1.87e-06	2	48	2	24850280
Pubmed	Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population.	CHRNA4 CHRNB2	1.87e-06	2	48	2	18762859
Pubmed	Galantamine is an allosterically potentiating ligand of the human alpha4/beta2 nAChR.	CHRNA4 CHRNB2	1.87e-06	2	48	2	11261808
Pubmed	Chemistry, pharmacology, and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile. Part II.	CHRNA4 CHRNB2	1.87e-06	2	48	2	23734673
Pubmed	Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors.	CHRNA4 CHRNB2	1.87e-06	2	48	2	30176987
Pubmed	Structural principles of distinct assemblies of the human α4β2 nicotinic receptor.	CHRNA4 CHRNB2	1.87e-06	2	48	2	29720657
Pubmed	Nicotinic α5 subunits drive developmental changes in the activation and morphology of prefrontal cortex layer VI neurons.	CHRNA4 CHRNA5	1.87e-06	2	48	2	22030359
Pubmed	Exocytic trafficking is required for nicotine-induced up-regulation of alpha 4 beta 2 nicotinic acetylcholine receptors.	CHRNA4 CHRNB2	1.87e-06	2	48	2	15741168
Pubmed	Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.	DUSP1 DUSP4	1.87e-06	2	48	2	22993413
Pubmed	Expression of water-soluble, ligand-binding concatameric extracellular domains of the human neuronal nicotinic receptor alpha4 and beta2 subunits in the yeast Pichia pastoris: glycosylation is not required for ligand binding.	CHRNA4 CHRNB2	1.87e-06	2	48	2	21252231
Pubmed	NMR resolved multiple anesthetic binding sites in the TM domains of the α4β2 nAChR.	CHRNA4 CHRNB2	1.87e-06	2	48	2	23000369
Pubmed	Nicotine upregulates its own receptors through enhanced intracellular maturation.	CHRNA4 CHRNB2	1.87e-06	2	48	2	15944128
Pubmed	The fifth subunit of the (α4β2)2 β2 nicotinic ACh receptor modulates maximal ACh responses.	CHRNA4 CHRNB2	1.87e-06	2	48	2	28600847
Pubmed	Cyclic AMP-dependent protein kinase A and protein kinase C phosphorylate alpha4beta2 nicotinic receptor subunits at distinct stages of receptor formation and maturation.	CHRNA4 CHRNB2	1.87e-06	2	48	2	19101612
Pubmed	α4β2∗ nicotinic receptors stimulate GABA release onto fast-spiking cells in layer V of mouse prefrontal (Fr2) cortex.	CHRNA4 CHRNB2	1.87e-06	2	48	2	27793780
Pubmed	Chronic sazetidine-A maintains anxiolytic effects and slower weight gain following chronic nicotine without maintaining increased density of nicotinic receptors in rodent brain.	CHRNA4 CHRNB2	1.87e-06	2	48	2	24422997
Pubmed	Thalamic nicotinic receptors implicated in disturbed consciousness in dementia with Lewy bodies.	CHRNA4 CHRNB2	1.87e-06	2	48	2	16023355
Pubmed	Association of idiopathic generalized epilepsy with polymorphisms in the neuronal nicotinic acetylcholine receptor subunits.	CHRNA4 CHRNB2	1.87e-06	2	48	2	17385675
Pubmed	Requirement of the nicotinic acetylcholine receptor beta 2 subunit for the anatomical and functional development of the visual system.	CHRNA4 CHRNB2	1.87e-06	2	48	2	11344259
Pubmed	Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors.	CHRNA4 CHRNB2	1.87e-06	2	48	2	24982426
Pubmed	The neuronal nicotinic alpha4beta2 receptor has a high maximal probability of being open.	CHRNA4 CHRNB2	1.87e-06	2	48	2	20649589
Pubmed	High-affinity α4β2 nicotinic receptors mediate the impairing effects of acute nicotine on contextual fear extinction.	CHRNA4 CHRNB2	1.87e-06	2	48	2	26688111
Pubmed	Nicotine acts as a pharmacological chaperone to up-regulate human alpha4beta2 acetylcholine receptors.	CHRNA4 CHRNB2	1.87e-06	2	48	2	16183856
Pubmed	Molecular basis of reactive oxygen species-induced inactivation of α4β2 nicotinic acetylcholine receptors.	CHRNA4 CHRNB2	1.87e-06	2	48	2	27445102
Pubmed	Sleep-related hypermotor epilepsy associated mutations uncover important kinetic roles of α4β2- nicotinic acetylcholine receptor intracellular structures.	CHRNA4 CHRNB2	1.87e-06	2	48	2	33657187
Pubmed	Structural characterization and agonist binding to human α4β2 nicotinic receptors.	CHRNA4 CHRNB2	1.87e-06	2	48	2	21396349
Pubmed	Additional acetylcholine (ACh) binding site at alpha4/alpha4 interface of (alpha4beta2)2alpha4 nicotinic receptor influences agonist sensitivity.	CHRNA4 CHRNB2	1.87e-06	2	48	2	21757735
Pubmed	Effects of varenicline on alpha4-containing nicotinic acetylcholine receptor expression and cognitive performance in mice.	CHRNA4 CHRNB2	1.87e-06	2	48	2	27012889
Pubmed	Possible association of nicotinic acetylcholine receptor gene (CHRNA4 and CHRNB2) polymorphisms with nicotine dependence in Japanese males: an exploratory study.	CHRNA4 CHRNB2	1.87e-06	2	48	2	23037950
Pubmed	Long sleep and short sleep mice differ in nicotine-stimulated 86Rb+ efflux and alpha4 nicotinic receptor subunit cDNA sequence.	CHRNA4 CHRNB2	1.87e-06	2	48	2	11434511
Pubmed	Catecholamine outflow from mouse and rat brain slice preparations evoked by nicotinic acetylcholine receptor activation and electrical field stimulation.	CHRNA5 CHRNB2	1.87e-06	2	48	2	17401441
Pubmed	No evidence for association between 19 cholinergic genes and bipolar disorder.	CHRNA4 CHRNA5 CHRNB2	2.35e-06	19	48	3	17373692
Pubmed	Differential phosphorylation of Smad1 integrates BMP and neurotrophin pathways through Erk/Dusp in axon development.	DUSP2 DUSP4 DUSP9	4.29e-06	23	48	3	23665221
Interaction	P2RX2 interactions	SGCB CHRNA4 CHRNA5 CHRNB2 CLPTM1	2.97e-07	70	41	5	int:P2RX2
Interaction	CHRNA4 interactions	PACC1 SGCB CHRNA4 CHRNA5 CHRNB2 GRAMD1A	7.85e-07	159	41	6	int:CHRNA4
Interaction	CHRNA3 interactions	CHRNA5 CHRNB2 GRAMD1A ITPR2	1.15e-06	39	41	4	int:CHRNA3
Interaction	CHRNB2 interactions	PACC1 CHRNA4 CHRNA5 CHRNB2 GRAMD1A	2.05e-06	103	41	5	int:CHRNB2
Interaction	CHRNB4 interactions	SGCB CHRNA4 CHRNA5 GRAMD1A	1.37e-05	72	41	4	int:CHRNB4
Interaction	ABHD14B interactions	DUSP1 DUSP2 DUSP4	2.75e-05	29	41	3	int:ABHD14B
Interaction	CCR6 interactions	DERL2 ATP8B2 CLPTM1 ITPR2	3.18e-05	89	41	4	int:CCR6
Interaction	HTR3A interactions	SGCB ATP8B2 GRAMD1A CLPTM1	6.78e-05	108	41	4	int:HTR3A
Interaction	PACC1 interactions	PACC1 NUP160 CHRNA4 CHRNB2	9.89e-05	119	41	4	int:PACC1
Cytoband	12q24	P2RX7 CIT	3.16e-04	25	48	2	12q24
Cytoband	1q21.3	ATP8B2 CHRNB2	6.73e-03	117	48	2	1q21.3
GeneFamily	MAP kinase phosphatases	DUSP1 DUSP2 DUSP4 DUSP9	6.03e-09	11	39	4	895
GeneFamily	Cholinergic receptors nicotinic subunits	CHRNA4 CHRNA5 CHRNB2	5.10e-06	16	39	3	173
GeneFamily	Dyneins, axonemal	DNAH9 DNAH11	6.04e-04	17	39	2	536
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CSMD1 SVEP1	6.71e-03	57	39	2	1179
GeneFamily	Olfactory receptors, family 10	OR10A7 OR10J1	8.91e-03	66	39	2	157
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F ANO2 GRIN2B CSMD1 DNAH9 RYR3 DNAH11	1.09e-09	184	48	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F ANO2 GRIN2B CSMD1 DNAH9 RYR3 DNAH11	1.09e-09	184	48	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F ANO2 GRIN2B CSMD1 DNAH9 RYR3 DNAH11	1.09e-09	184	48	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Ciliated_cells-A-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 CYP2J2 DNAH9 DNAH11	8.86e-07	163	48	5	43194c6127df1ce3d29242f719645de3c11fd7c0
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GRIN2B CSMD1 PTGS1 GPR75 ITPR2	1.06e-06	169	48	5	05e12524d68d409fed386ffad233305683b4575b
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ERICH3 SERPINI2 EFCAB10 DNAH9 DNAH11	2.42e-06	200	48	5	af6a551f83808c1c839df7ba7b1702ca28ea6e1b
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	ERICH3 SERPINI2 DNAH9 DNAH11	2.11e-05	151	48	4	8216462e723fec2797387929dde095370947e10a
ToppCell	Ciliated_cells-A-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 DUSP9 DNAH11	2.28e-05	154	48	4	3b938e23324f7edb56797b4a76fb96ff588142cf
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIN2B DNAH9 SVEP1 RYR3	2.65e-05	160	48	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIN2B DNAH9 SVEP1 RYR3	2.65e-05	160	48	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	15-Distal-Epithelial-Multiciliated_precursor\|Distal / Age, Tissue, Lineage and Cell class	ERICH3 EFCAB10 DNAH9 DNAH11	3.14e-05	167	48	4	442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GRIN2B CSMD1 PTGS1 ITPR2	3.21e-05	168	48	4	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D175\|Adult / Lineage, Cell type, age group and donor	ANO2 GRIN2B PTGS1 CDH10	3.29e-05	169	48	4	e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCell	Lymphoid-Lymphoid-T_cells_(Cd8+_T_cell)\|Lymphoid / shred on cell class and cell subclass (v4)	ATP8B2 CDH10 SVEP1 DUSP1	3.36e-05	170	48	4	20fd1a312c81c1bf3c5d2d6caf9b578e6b7a4171
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIN2B G6PC2 CSMD1 DNAH9	3.76e-05	175	48	4	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	facs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERICH3 EFCAB10 DNAH9 DNAH11	3.85e-05	176	48	4	ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERICH3 FER1L5 DNAH9 DNAH11	3.85e-05	176	48	4	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	Ciliated_cells-A-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 DNAH9 DNAH11	4.02e-05	178	48	4	255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	4.02e-05	178	48	4	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	15-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	SERPINI2 EFCAB10 DNAH9 DNAH11	4.02e-05	178	48	4	d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERICH3 EFCAB10 DNAH9 DNAH11	4.11e-05	179	48	4	d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERICH3 EFCAB10 DNAH9 DNAH11	4.11e-05	179	48	4	8a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 GRIN2B G6PC2 CIT	4.11e-05	179	48	4	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD1 P2RX7 ADCY1 DUSP4	4.20e-05	180	48	4	da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell	droplet-Heart-nan-3m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD1 P2RX7 ADCY1 DUSP4	4.20e-05	180	48	4	5b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD1 P2RX7 ADCY1 DUSP4	4.20e-05	180	48	4	50758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell	facs-GAT-Fat-3m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERICH3 EFCAB10 DNAH9 DNAH11	4.29e-05	181	48	4	e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCell	facs-GAT-Fat-3m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERICH3 EFCAB10 DNAH9 DNAH11	4.29e-05	181	48	4	11cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Ciliated\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ERICH3 SERPINI2 EFCAB10 DNAH9	4.29e-05	181	48	4	8eed9d46d924b16f6dd1a025ff612244b02b4391
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	4.29e-05	181	48	4	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	facs-GAT-Fat-3m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERICH3 EFCAB10 DNAH9 DNAH11	4.29e-05	181	48	4	5ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	4.39e-05	182	48	4	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	ERICH3 SERPINI2 DNAH9 DNAH11	4.39e-05	182	48	4	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	4.48e-05	183	48	4	b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|367C / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	4.48e-05	183	48	4	cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCell	P07-Epithelial-airway_epithelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ERICH3 EFCAB10 DNAH9 DNAH11	4.58e-05	184	48	4	a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCell	P07-Epithelial-airway_epithelial_cell-club_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ERICH3 EFCAB10 DNAH9 DNAH11	4.58e-05	184	48	4	ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCell	Ciliated_cells-A-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 DNAH9 DNAH11	4.58e-05	184	48	4	07c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	4.58e-05	184	48	4	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GRIN2B CSMD1 PTGS1 ITPR2	4.67e-05	185	48	4	686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 DNAH9 DNAH11	4.67e-05	185	48	4	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	15-Airway-Epithelial-Multiciliated_cell\|Airway / Age, Tissue, Lineage and Cell class	ERICH3 EFCAB10 DNAH9 DNAH11	4.67e-05	185	48	4	0998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	4.67e-05	185	48	4	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	4.67e-05	185	48	4	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	ERICH3 SERPINI2 DNAH9 DNAH11	4.67e-05	185	48	4	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	Ciliated_cells-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 DNAH9 DNAH11	4.77e-05	186	48	4	f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERICH3 CSMD1 CHRNB2 DUSP4	4.77e-05	186	48	4	18fd311252299d6d30ddb32002ed069056108206
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERICH3 EFCAB10 DNAH9 DNAH11	4.77e-05	186	48	4	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERICH3 EFCAB10 DNAH9 DNAH11	4.77e-05	186	48	4	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)\|390C / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	4.77e-05	186	48	4	708c5edefe36c91df27cf53c1b5101fb2030cc5a
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	4.77e-05	186	48	4	029390c4aaf64e6bcd86124cd4a6dd2e6f3a374b
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERICH3 EFCAB10 DNAH9 DNAH11	4.87e-05	187	48	4	04dba2ed09ee4180830bdf0191921696697ea234
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 DNAH9 DNAH11	4.87e-05	187	48	4	2b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	4.87e-05	187	48	4	88f785932e67c613db0dda84496de351359ed962
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	4.87e-05	187	48	4	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	4.87e-05	187	48	4	8896a00b30d11b90ca42726d4e122174a30b161b
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNM3 ADCY1 SVEP1 DNAH11	4.87e-05	187	48	4	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	21-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	ERICH3 EFCAB10 DNAH9 DNAH11	4.87e-05	187	48	4	1a2178a195d078d1963947b327c6d0d4f2f48341
ToppCell	facs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERICH3 EFCAB10 DNAH9 DNAH11	4.87e-05	187	48	4	805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCell	multiciliated\|World / shred by cell class for bronchial biopsy	ERICH3 EFCAB10 DNAH9 DNAH11	4.98e-05	188	48	4	6833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	4.98e-05	188	48	4	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	21-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	ERICH3 EFCAB10 DNAH9 DNAH11	4.98e-05	188	48	4	803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	4.98e-05	188	48	4	82c006f43c93f4a867953a446864f02b44536a23
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	4.98e-05	188	48	4	da59b5c0a4b11690a39a964c1a0a83e66aa0972b
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	4.98e-05	188	48	4	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	Ciliated_cells-B-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 DNAH9 DNAH11	4.98e-05	188	48	4	606907c865bd2f11bb6474932716550f7723d858
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	4.98e-05	188	48	4	2b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ERICH3 EFCAB10 DNAH9 DNAH11	4.98e-05	188	48	4	5ba5cbb403518026e9040379fb5d99339ea977d8
ToppCell	(7)_Epithelial-F_(Ciliated)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ERICH3 EFCAB10 DNAH9 DNAH11	4.98e-05	188	48	4	9a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ERICH3 SERPINI2 DNAH9 DNAH11	5.08e-05	189	48	4	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	5.08e-05	189	48	4	68a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ERICH3 EFCAB10 DNAH9 DNAH11	5.08e-05	189	48	4	dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell	Control-Epithelial-Ciliated\|Control / Disease state, Lineage and Cell class	ERICH3 SERPINI2 DNAH9 DNAH11	5.08e-05	189	48	4	c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANO2 CSMD1 PTGS1 ITPR2	5.08e-05	189	48	4	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ERICH3 EFCAB10 DNAH9 DNAH11	5.08e-05	189	48	4	a3cd4c2da4feb9bdcd8957f3e344d095da1367b8
ToppCell	Multiciliated\|World / shred by cell class for nasal brushing	ERICH3 EFCAB10 DNAH9 DNAH11	5.08e-05	189	48	4	34b110aef839376228c5a403a6b5047a945f472b
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	ERICH3 SERPINI2 DNAH9 DNAH11	5.08e-05	189	48	4	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	ERICH3 SERPINI2 DNAH9 DNAH11	5.08e-05	189	48	4	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	ERICH3 SERPINI2 DNAH9 DNAH11	5.08e-05	189	48	4	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	Ciliated\|World / shred by cell class for parenchyma	ERICH3 EFCAB10 DNAH9 DNAH11	5.08e-05	189	48	4	711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ERICH3 EFCAB10 DNAH9 DNAH11	5.08e-05	189	48	4	93b1026bb1ba759e5704561c9a5de14a30c08894
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	ERICH3 EFCAB10 DNAH9 DNAH11	5.18e-05	190	48	4	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)\|343B / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	5.18e-05	190	48	4	169e600e95878000acf5d11f813f9028c7249646
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	5.18e-05	190	48	4	0cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCell	Epithelial_cells-Ciliated_cells-A\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 DNAH9 DNAH11	5.18e-05	190	48	4	549d813a8f23b175875e53347928941f143e236c
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ERICH3 EFCAB10 DNAH9 DNAH11	5.18e-05	190	48	4	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	Ciliated_cells-B\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 DNAH9 DNAH11	5.18e-05	190	48	4	7031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ERICH3 EFCAB10 DNAH9 DNAH11	5.18e-05	190	48	4	a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCell	cellseq2-Epithelial-Epithelial_Airway\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ERICH3 EFCAB10 DNAH9 DNAH11	5.18e-05	190	48	4	17829f4de31b3d9e4d71ba4817d18842aa699773
ToppCell	Ciliated_cells-A\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 DNAH9 DNAH11	5.18e-05	190	48	4	cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCell	Epithelial_cells-Ciliated_cells-B\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	ERICH3 EFCAB10 DNAH9 DNAH11	5.18e-05	190	48	4	426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERICH3 EFCAB10 DNAH9 DNAH11	5.29e-05	191	48	4	649fcb62ad15de2f83e61591e43923a717664ae7
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ERICH3 EFCAB10 DNAH9 DNAH11	5.29e-05	191	48	4	7b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERICH3 EFCAB10 DNAH9 DNAH11	5.29e-05	191	48	4	9621e22e14ea069f22713947c9faa2d882abe5fe
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	5.29e-05	191	48	4	8a5a2188b13ef4bbfd626a42565566708a751c1b
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ERICH3 EFCAB10 DNAH9 DNAH11	5.29e-05	191	48	4	9f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	5.29e-05	191	48	4	dad675251e129254955eac179c84a641a4864586
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ERICH3 EFCAB10 DNAH9 DNAH11	5.29e-05	191	48	4	fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	ERICH3 DNAH9 RYR3 DNAH11	5.29e-05	191	48	4	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ERICH3 EFCAB10 DNAH9 DNAH11	5.29e-05	191	48	4	6d2cf41ee946137c039ddcc13593fc3f670afbba
Computational	Genes in the cancer module 267.	P2RX7 CHRNA4 CHRNB2	7.05e-06	15	28	3	MODULE_267
Drug	beta-erythroidine	CHRNA4 CHRNA5 CHRNB2	3.29e-08	4	47	3	ctd:C004873
Drug	NSC7524	CACNA1F GRIN2B CIT ADCY1 CHRNA4 CHRNB2 RYR3	8.92e-08	182	47	7	CID000005657
Drug	decamethonium	CHRNA4 CHRNA5 CHRNB2	1.64e-07	6	47	3	ctd:C033019
Drug	Dimethylphenylpiperazinium Iodide	CHRNA4 CHRNA5 CHRNB2	4.58e-07	8	47	3	ctd:D004246
Drug	epibatidine	CHRNA4 CHRNA5 CHRNB2	4.58e-07	8	47	3	ctd:C082748
Drug	Excitatory Amino Acid Antagonists	GRIN2B CHRNA4 CHRNB2	6.87e-07	9	47	3	ctd:D018691
Drug	pozanicline	CHRNA4 CHRNA5 CHRNB2	6.87e-07	9	47	3	ctd:C108326
Drug	N-methyl-DL-aspartic acid	SLC6A9 CACNA1F GRIN2B CIT SGCB ADCY1 PTGS1 CHRNA4 CHRNB2 RYR3	7.18e-07	655	47	10	CID000004376
Drug	cytisine	CHRNA4 CHRNA5 CHRNB2	1.34e-06	11	47	3	ctd:C004712
Drug	AC1O3MDH	GRIN2B CIT SGCB PTGS1 RYR3	2.16e-06	102	47	5	CID006332158
Drug	halothane	ATP5F1D CACNA1F CYP2J2 ADCY1 CHRNA4 CHRNB2 RYR3	3.48e-06	314	47	7	CID000003562
Drug	subecholine	CHRNA4 CHRNB2	4.17e-06	2	47	2	ctd:C009335
Drug	3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole	CHRNA4 CHRNB2	4.17e-06	2	47	2	ctd:C088383
Drug	ispronicline	CHRNA4 CHRNB2	4.17e-06	2	47	2	ctd:C490152
Drug	5-(2-azetidinylmethoxy)-2-chloropyridine	CHRNA4 CHRNB2	4.17e-06	2	47	2	ctd:C109763
Drug	metanicotine	CHRNA4 CHRNB2	4.17e-06	2	47	2	ctd:C012419
Drug	3-(2-(pyrrolidinyl)methoxy)pyridine	CHRNA4 CHRNB2	4.17e-06	2	47	2	ctd:C116733
Drug	Bridged Bicyclo Compounds, Heterocyclic	CHRNA4 CHRNB2	4.17e-06	2	47	2	ctd:D019086
Drug	TC 2559	CHRNA4 CHRNB2	4.17e-06	2	47	2	ctd:C419442
Drug	Fire Trol 934	CHRNA4 CHRNB2	4.17e-06	2	47	2	ctd:C508049
Drug	Pyrazines	PTGS1 CHRNA4 CHRNB2	4.53e-06	16	47	3	ctd:D011719
Drug	Hexamethonium	CHRNA4 CHRNA5 CHRNB2	4.53e-06	16	47	3	ctd:D018738
Drug	Calcium	CACNA1F P2RX7 PTGS1 CHRNA4 DUSP1 CHRNB2 RYR3 ITPR2	6.84e-06	493	47	8	ctd:D002118
Drug	AC1L1IZE	AARS1 P2RX7 DNAH9 RYR3 DNAH11	7.38e-06	131	47	5	CID000004799
Drug	nicardipine	CACNA1F SGCB CHRNA4 CHRNB2 RYR3	1.21e-05	145	47	5	CID000004473
Drug	ponceau 4R	CHRNA4 CHRNB2	1.25e-05	3	47	2	ctd:C576297
Drug	13,19-didesmethyl spirolide C	CHRNA4 CHRNB2	1.25e-05	3	47	2	ctd:C544516
Drug	sazetidine-A	CHRNA4 CHRNB2	1.25e-05	3	47	2	ctd:C514816
Drug	Alcuronium	CHRNA4 CHRNB2	1.25e-05	3	47	2	ctd:D000443
Drug	A 85380	CHRNA4 CHRNB2	1.25e-05	3	47	2	ctd:C104288
Drug	13-desmethylspirolide C	CHRNA4 CHRNB2	1.25e-05	3	47	2	ctd:C517170
Drug	desformylflustrabromine	CHRNA4 CHRNB2	1.25e-05	3	47	2	ctd:C524215
Drug	brilliant blue	CHRNA4 CHRNB2	1.25e-05	3	47	2	ctd:C006796
Drug	Barium	CACNA1F P2RX7 CHRNA4 CHRNB2	1.48e-05	72	47	4	ctd:D001464
Drug	sodium nitroprusside	GRIN2B SGCB ADCY1 PTGS1 DUSP1 RYR3	1.55e-05	261	47	6	CID000045469
Drug	caffeine	CACNA1F GRIN2B P2RX7 CYP2J2 ADCY1 CHRNA4 CHRNB2 RYR3	1.77e-05	562	47	8	CID000002519
Drug	7-NI	GRIN2B CIT SGCB PTGS1	2.03e-05	78	47	4	CID000001893
Drug	guanosine 3',5'-cyclic monophosphoric acid	CACNA1F GRIN2B DNAH9 SGCB ADCY1 PTGS1 DUSP1 RYR3	2.13e-05	577	47	8	CID000000295
Drug	Anabasine	CHRNA4 CHRNB2	2.50e-05	4	47	2	ctd:D000691
Drug	Amaranth Dye	CHRNA4 CHRNB2	2.50e-05	4	47	2	ctd:D000548
Drug	2-(1'-methyl-2'-pyrrolidinyl)-7-hydroxy-1,4-benzodioxane	CHRNA4 CHRNB2	2.50e-05	4	47	2	ctd:C569671
Drug	Acetylthiocholine	CHRNA4 CHRNB2	2.50e-05	4	47	2	ctd:D000122
Drug	Succinylcholine	CHRNA4 CHRNB2	2.50e-05	4	47	2	ctd:D013390
Drug	flazin	SGCB PTGS1	2.50e-05	4	47	2	CID005377686
Drug	alpha-conotoxin MII	CHRNA5 CHRNB2	2.50e-05	4	47	2	ctd:C098872
Drug	U46619	CACNA1F SGCB ADCY1 PTGS1 DUSP2 RYR3	2.55e-05	285	47	6	CID000005618
Drug	memantine	SLC6A9 GRIN2B CHRNA4 CHRNB2	2.99e-05	86	47	4	CID000004054
Drug	AC1LALA3	CIT DUSP1 DUSP2	3.22e-05	30	47	3	CID000490573
Drug	sodium alpha-oxyhyponitrite	GRIN2B SGCB DUSP2	3.22e-05	30	47	3	CID010129945
Drug	metolachlor	DUSP1 DUSP2 DUSP4 DUSP9	3.27e-05	88	47	4	CID000004169
Drug	tetracaine	ADCY1 CHRNA4 CHRNB2 RYR3	3.27e-05	88	47	4	CID000005411
Drug	Allura Red AC Dye	CHRNA4 CHRNB2	4.15e-05	5	47	2	ctd:C005915
Drug	N-(1,2,3,4-tetrahydro-1-naphthyl)-4-nitroaniline	CHRNA4 CHRNB2	4.15e-05	5	47	2	ctd:C524978
Drug	cisatracurium	CHRNA4 CHRNB2	4.15e-05	5	47	2	ctd:C101584
Drug	methyllycaconitine	CHRNA4 CHRNA5 CHRNB2	4.31e-05	33	47	3	ctd:C054634
Drug	p-nitrophenyl phosphate	G6PC2 DUSP1 DUSP2 DUSP4 DUSP9	4.89e-05	194	47	5	CID000000378
Drug	gamma-aminobutyric acid	SLC6A9 CACNA1F GRIN2B CIT CHRNA4 CHRNB2 RYR3	4.96e-05	474	47	7	CID000000119
Drug	Paroxetine maleate [64006-44-6]; Down 200; 1uM; PC3; HT_HG-U133A	NUP160 SVEP1 DUSP2 GPR75 DUSP9	5.01e-05	195	47	5	3821_DN
Drug	EPTC	CHRNA4 DUSP2 CHRNB2	5.15e-05	35	47	3	CID000012968
Drug	BAPTA	GRIN2B P2RX7 CHRNA4 DUSP1 DUSP2 RYR3	5.21e-05	324	47	6	CID000104751
Drug	Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A	SLC6A9 CACNA1F ATP8B2 SVEP1 CHRNB2	5.26e-05	197	47	5	4120_UP
Drug	Equilin [474-86-2]; Up 200; 15uM; HL60; HT_HG-U133A	SGCB CDH10 SVEP1 DUSP1 DUSP4	5.26e-05	197	47	5	3039_UP
Drug	Guaifenesin [93-14-1]; Down 200; 20.2uM; HL60; HT_HG-U133A	SGCB ATP8B2 NUP160 DUSP2 ITPR2	5.26e-05	197	47	5	2569_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A	G6PC2 DNAH9 PTGS1 CDH10 GPR75	5.39e-05	198	47	5	3973_UP
Drug	Methapyrilene hydrochloride [135-23-9]; Up 200; 13.4uM; MCF7; HT_HG-U133A	RAG2 ATP8B2 SVEP1 GPR75 DUSP9	5.52e-05	199	47	5	3205_UP
Drug	Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; PC3; HT_HG-U133A	RAG2 P2RX7 CYP2J2 CDH10 SVEP1	5.52e-05	199	47	5	4648_UP
Drug	PhTX-343	GRIN2B CHRNA4 CHRNB2	5.61e-05	36	47	3	CID000159548
Drug	enprofylline	P2RX7 ADCY1 PTGS1	5.61e-05	36	47	3	CID000001676
Drug	Pyridines	CHRNA4 CHRNB2	6.22e-05	6	47	2	ctd:D011725
Drug	Food Coloring Agents	CHRNA4 CHRNB2	6.22e-05	6	47	2	ctd:D005505
Drug	Nicotine	CHRNA4 CHRNB2	6.22e-05	6	47	2	DB00184
Drug	Tartrazine	CHRNA4 CHRNB2	6.22e-05	6	47	2	ctd:D013645
Drug	Lobeline	CHRNA4 CHRNB2	8.70e-05	7	47	2	ctd:D008120
Drug	mivacurium	CHRNA4 CHRNB2	8.70e-05	7	47	2	ctd:C049430
Drug	Chlorisondamine	CHRNA4 CHRNB2	8.70e-05	7	47	2	ctd:D002714
Drug	EPTC	CHRNA4 CHRNB2	8.70e-05	7	47	2	ctd:C036251
Drug	Atracurium	CHRNA4 CHRNB2	8.70e-05	7	47	2	ctd:D001279
Drug	Indigo Carmine	CHRNA4 CHRNB2	8.70e-05	7	47	2	ctd:D007203
Drug	3,5-dibromo-2-(2,4-dibromophenoxy)phenol	CHRNA4 CHRNB2	8.70e-05	7	47	2	ctd:C085794
Drug	lamotrigine	CACNA1F GRIN2B PTGS1 RYR3	9.63e-05	116	47	4	CID000003878
Drug	dihydro-beta-erythroidine	GRIN2B CHRNA4 CHRNB2	1.03e-04	44	47	3	CID000031762
Drug	philanthotoxin	GRIN2B CHRNA4 CHRNB2	1.10e-04	45	47	3	CID000115201
Drug	potassium phosphate	ADCY1 DUSP1 DUSP2 DUSP4	1.13e-04	121	47	4	CID000024450
Drug	sodium	SLC6A18 SLC6A9 P2RX7 CIT ADCY1 PTGS1 CHRNA4 CHRNB2 RYR3	1.15e-04	944	47	9	CID000000923
Drug	Rivastigmine	CHRNA4 CHRNB2	1.16e-04	8	47	2	ctd:D000068836
Drug	FG 9041	CHRNA4 CHRNB2	1.16e-04	8	47	2	ctd:C056723
Drug	NSC135065	SGCB PTGS1	1.16e-04	8	47	2	CID000282014
Drug	Galantamine	CHRNA4 CHRNB2	1.16e-04	8	47	2	DB00674
Drug	fluo-3	GRIN2B P2RX7 CIT RYR3	1.17e-04	122	47	4	CID000104978
Drug	Mecamylamine	CHRNA4 CHRNA5 CHRNB2	1.18e-04	46	47	3	ctd:D008464
Drug	glutamate	SLC6A9 CACNA1F GRIN2B P2RX7 CIT ADCY1 CHRNA4 CHRNB2 RYR3	1.32e-04	962	47	9	CID000000611
Drug	neuroNal	CHRNA4 CHRNA5 CHRNB2	1.42e-04	49	47	3	CID000010535
Drug	Galantamine	CHRNA4 CHRNB2	1.49e-04	9	47	2	ctd:D005702
Drug	antimony trioxide	CHRNA4 CHRNB2	1.49e-04	9	47	2	ctd:C037554
Drug	fenoxycarb	CHRNA4 CHRNB2	1.49e-04	9	47	2	ctd:C052034
Drug	mepivacaine	SERPINI2 CHRNA4 CHRNB2	1.60e-04	51	47	3	CID000004062
Drug	noradrealine	CACNA1F P2RX7 SGCB ADCY1 CHRNA4 CHRNB2 RYR3	1.65e-04	575	47	7	CID000000951
Drug	AC1L9ZFX	RAG2 GRIN2B CHRNA4 CHRNB2	1.68e-04	134	47	4	CID000504578
Drug	rolipram	GRIN2B CIT SGCB ADCY1 PTGS1	1.71e-04	253	47	5	CID000005092
Drug	donepezil	GRIN2B CHRNA4 CHRNB2	1.80e-04	53	47	3	CID000003152
Disease	nicotine dependence	CDH10 CHRNA4 CHRNA5 CHRNB2	6.78e-06	78	46	4	EFO_0003768
Disease	Frontal Epilepsy, Benign, Childhood	CHRNA4 CHRNB2	1.42e-05	4	46	2	C0393671
Disease	Epilepsy, Cingulate	CHRNA4 CHRNB2	1.42e-05	4	46	2	C0393684
Disease	Epilepsy, Supplementary Motor	CHRNA4 CHRNB2	1.42e-05	4	46	2	C0393683
Disease	Epilepsy, Opercular	CHRNA4 CHRNB2	1.42e-05	4	46	2	C0393688
Disease	Epilepsy, Orbito-Frontal	CHRNA4 CHRNB2	1.42e-05	4	46	2	C0751643
Disease	Epilepsy, Anterior Fronto-Polar	CHRNA4 CHRNB2	1.42e-05	4	46	2	C0751642
Disease	Epilepsy, Frontal Lobe	CHRNA4 CHRNB2	1.42e-05	4	46	2	C0085541
Disease	Autosomal dominant nocturnal frontal lobe epilepsy	CHRNA4 CHRNB2	1.42e-05	4	46	2	cv:C3696898
Disease	preeclampsia, fetal genotype effect measurement	CDH10 ITPR2	2.37e-05	5	46	2	EFO_0000668, EFO_0007959
Disease	nicotine dependence (is_implicated_in)	CHRNA4 CHRNA5	3.55e-05	6	46	2	DOID:0050742 (is_implicated_in)
Disease	Mental Depression	GRIN2B P2RX7 CHRNA4 DUSP1 DUSP4	4.67e-05	254	46	5	C0011570
Disease	Sleep Disorders	CHRNA4 CHRNB2	4.97e-05	7	46	2	C0851578
Disease	Autosomal Dominant Nocturnal Frontal Lobe Epilepsy	CHRNA4 CHRNB2	4.97e-05	7	46	2	C3696898
Disease	Subwakefullness Syndrome	CHRNA4 CHRNB2	4.97e-05	7	46	2	C0751511
Disease	Sleep-Related Neurogenic Tachypnea	CHRNA4 CHRNB2	4.97e-05	7	46	2	C0751510
Disease	Short Sleeper Syndrome	CHRNA4 CHRNB2	4.97e-05	7	46	2	C0751509
Disease	Long Sleeper Syndrome	CHRNA4 CHRNB2	4.97e-05	7	46	2	C0751508
Disease	Sleep Wake Disorders	CHRNA4 CHRNB2	4.97e-05	7	46	2	C4042891
Disease	Schizophrenia	SLC6A9 CACNA1F GRIN2B CSMD1 PTGS1 CHRNA4 CHRNA5 CHRNB2	5.93e-05	883	46	8	C0036341
Disease	Depressive disorder	GRIN2B P2RX7 CHRNA4 DUSP1 DUSP4	8.59e-05	289	46	5	C0011581
Disease	C-reactive protein measurement	SLC6A9 P2RX7 CIT OR10J1 ATP8B2 DUSP1 CHRNB2 CLPTM1 DNAH11	8.68e-05	1206	46	9	EFO_0004458
Disease	Withdrawal Symptoms	ADCY1 CHRNA5 CHRNB2	1.03e-04	58	46	3	C0087169
Disease	Drug Withdrawal Symptoms	ADCY1 CHRNA5 CHRNB2	1.03e-04	58	46	3	C0086189
Disease	Substance Withdrawal Syndrome	ADCY1 CHRNA5 CHRNB2	1.03e-04	58	46	3	C0038587
Disease	TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding)	CHRNA4 CHRNA5	1.55e-04	12	46	2	C1861063
Disease	pre-eclampsia (implicated_via_orthology)	CYP2J2 PTGS1	1.83e-04	13	46	2	DOID:10591 (implicated_via_orthology)
Disease	behavioural disinhibition measurement	CSMD1 DNAH9 DNAH11	2.21e-04	75	46	3	EFO_0006946
Disease	alcohol use disorder (implicated_via_orthology)	ADCY1 CHRNA4 CHRNB2 RYR3	2.43e-04	195	46	4	DOID:1574 (implicated_via_orthology)
Disease	intracerebral hemorrhage	OR52E4 OMA1	2.81e-04	16	46	2	EFO_0005669
Disease	congenital myasthenic syndrome (implicated_via_orthology)	CHRNA4 CHRNB2	2.81e-04	16	46	2	DOID:3635 (implicated_via_orthology)
Disease	phosphatidylcholine 40:6 measurement	CSMD1 DNAH9	3.19e-04	17	46	2	EFO_0010389
Disease	Attention Deficit Disorder	CHRNA4 CHRNB2	5.38e-04	22	46	2	C0041671
Disease	Minimal Brain Dysfunction	CHRNA4 CHRNB2	5.38e-04	22	46	2	C1321905
Disease	Attention deficit hyperactivity disorder	CHRNA4 CHRNB2	6.42e-04	24	46	2	C1263846
Disease	Alzheimer's disease (is_marker_for)	ATP5F1D GRIN2B PTGS1 CHRNA4	6.88e-04	257	46	4	DOID:10652 (is_marker_for)
Disease	Autistic Disorder	GRIN2B CDH10 CHRNA4 CHRNB2	7.29e-04	261	46	4	C0004352
Disease	pneumonia, COVID-19	OMA1 GRIN2B CSMD1	7.36e-04	113	46	3	EFO_0003106, MONDO_0100096
Disease	Alcoholic Intoxication, Chronic	GRIN2B CDH10 CHRNA4 CHRNA5	8.05e-04	268	46	4	C0001973
Disease	attention deficit hyperactivity disorder (implicated_via_orthology)	GRIN2B CHRNB2	8.76e-04	28	46	2	DOID:1094 (implicated_via_orthology)
Disease	Cone-Rod Dystrophy 2	PITPNM3 CACNA1F	9.40e-04	29	46	2	C3489532
Disease	parental longevity	GRIN2B CSMD1 CHRNA4 CHRNA5 RYR3	1.00e-03	494	46	5	EFO_0007796
Disease	Epileptic encephalopathy	GRIN2B RYR3	1.01e-03	30	46	2	C0543888
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	DUSP1 DUSP2 DUSP4	1.13e-03	131	46	3	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	DUSP1 DUSP2 DUSP4	1.13e-03	131	46	3	C4552091
Disease	Juvenile arthritis	DUSP1 DUSP2 DUSP4	1.13e-03	131	46	3	C3495559
Disease	Juvenile psoriatic arthritis	DUSP1 DUSP2 DUSP4	1.13e-03	131	46	3	C3714758
Disease	microcephaly (implicated_via_orthology)	AARS1 CIT	1.14e-03	32	46	2	DOID:10907 (implicated_via_orthology)
Disease	Juvenile-Onset Still Disease	DUSP1 DUSP2 DUSP4	1.23e-03	135	46	3	C0087031
Disease	primary dental caries	ANO2 GRIN2B	1.29e-03	34	46	2	EFO_0600095
Disease	emphysema imaging measurement	CSMD1 CHRNA4 CHRNA5	1.54e-03	146	46	3	EFO_0007626

Protein segments in the cluster

Peptide	Gene	Start	Entry
FPFSLTFFLNGMQVN	ERICH3	346	Q5RHP9
TFFPFDQQNCTMKFG	CHRNA4	166	P43681
TQAPQFLISTGNFMY	CSMD1	831	Q96PZ7
FFTSLMQKFTFRPPN	CYP2J2	461	P51589
NQMSFTFASPTQVFF	ATP5F1D	36	P30049
LSGFFNPQSFLTAIM	DNAH11	4376	Q96DT5
QPFFFTGAFPFNMQE	ANKRD40	246	Q6AI12
FDNPATVFFSIFMAL	ANO2	436	Q9NQ90
TFNNIMNFQRFLKFP	CIT	311	O14578
MLFSDSPFLQGFLQQ	GRAMD1A	386	Q96CP6
GLFDMFPNQFRFVGN	ATP8B2	1061	P98198
QPGFSLMNFDGQVFF	RAG2	16	P55895
ESIMNIVSGFFNSPF	ITPR2	1481	Q14571
PNGGITNFDNFFFAM	CACNA1F	306	O60840
AFFSFMTHRFGQNIP	OR52E4	256	Q8NGH9
GFTNNPEMQVSLFIF	OR10A7	16	Q8NGE5
PNFSFMGQLLQFETQ	DUSP2	296	Q05923
NISPNFNFMGQLLDF	DUSP9	326	Q99956
FIPDPQGTNLMFAFF	PTGS1	186	P23219
QPVNSFGFANSYIAM	GPR75	501	O95800
SFQEFLQSPNRVGFM	PACC1	206	Q9H813
PLQGNSFFVMTNFLK	P2RX7	96	Q99572
FFPFDLQNCSMKFGS	CHRNA5	176	P30532
QVGVMFASIPNFNDF	ADCY1	866	Q08828
SPNFSFMGQLLQFES	DUSP1	296	P28562
GVAFPFFMDNSNIVA	EFCAB10	56	A6NFE3
GQKFFFSLAAVNPNF	CDH10	521	Q9Y6N8
LNFMSNVGDPRNIFF	G6PC2	26	Q9NQR9
FLLGFQFIFASMQKP	EIF4G1	616	Q04637
LTGFFNPQSFLTAIM	DNAH9	4346	Q9NYC9
FLFFGPVGFNFLFNM	DERL2	61	Q9GZP9
NPYVRMNFFGLLNFQ	DERL2	136	Q9GZP9
IMFIGVNLTFFPQHF	MT-CO1	416	P00395
IISPNFSFMGQLLQF	DUSP4	316	Q13115
GTSMFPFQNILFIFL	FTH1P19	166	P0C7X4
QPISLAGCATQMFFF	OR10J1	101	P30954
IKMGNNPFFNEIFFQ	FER1L5	201	A0AVI2
IGMQFFDPRTQNILF	SGCB	166	Q16585
FQQMSPSRNFSFRLF	SVEP1	21	Q4LDE5
MYLQSLFTPGQFTNE	NUP160	456	Q12769
PNGQMFVFTGFLNSV	OMA1	301	Q96E52
FDNFAASPNLLMLAF	SLC6A18	471	Q96N87
GMFLQPLFQNYTTTT	CHRNB2	476	P17787
LTFGFITMTPQLFIN	CLPTM1	516	O96005
FANAGMNQFKPIFLN	AARS1	41	P49588
FENFNTDGLFFPVMS	RYR3	766	Q15413
IPLFFMELSFGQFAS	SLC6A9	151	P48067
AQSQFIANHPFLFIM	SERPINI2	361	O75830
LSQHNFPQGMIFFSD	PITPNM3	796	Q9BZ71
SMFFQFGPSIEQQAS	GRIN2B	141	Q13224