Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H2AXS139 kinase activity	ATM ATR	1.06e-05	3	38	2	GO:0035979
GeneOntologyMolecularFunction	histone H2AX kinase activity	ATM ATR	3.51e-05	5	38	2	GO:0141003
GeneOntologyMolecularFunction	histone modifying activity	KDM5B ATM HUWE1 ING3 ATR	7.00e-05	229	38	5	GO:0140993
GeneOntologyMolecularFunction	guanylyltransferase activity	FPGT TENT4B	7.36e-05	7	38	2	GO:0070568
GeneOntologyMolecularFunction	histone kinase activity	ATM ATR	1.29e-03	28	38	2	GO:0035173
GeneOntologyBiologicalProcess	telomerase catalytic core complex assembly	ATM ATR	3.31e-06	2	38	2	GO:1904868
GeneOntologyBiologicalProcess	positive regulation of telomerase catalytic core complex assembly	ATM ATR	3.31e-06	2	38	2	GO:1904884
GeneOntologyBiologicalProcess	regulation of telomerase catalytic core complex assembly	ATM ATR	3.31e-06	2	38	2	GO:1904882
GeneOntologyBiologicalProcess	growth hormone secretion	CACNA1C RAB1A ARHGEF7	8.67e-06	22	38	3	GO:0030252
GeneOntologyBiologicalProcess	establishment of RNA localization to telomere	ATM ATR	9.90e-06	3	38	2	GO:0097694
GeneOntologyBiologicalProcess	establishment of protein-containing complex localization to telomere	ATM ATR	9.90e-06	3	38	2	GO:0097695
GeneOntologyBiologicalProcess	negative regulation of chromosome organization	KNTC1 ATM TENT4B CCNB1	4.41e-05	107	38	4	GO:2001251
GeneOntologyBiologicalProcess	telomerase holoenzyme complex assembly	ATM ATR	4.93e-05	6	38	2	GO:1905323
GeneOntologyBiologicalProcess	negative regulation of organelle organization	KNTC1 ATM TENT4B HUWE1 ARHGEF7 CCNB1	1.11e-04	421	38	6	GO:0010639
GeneOntologyBiologicalProcess	mitotic spindle assembly checkpoint signaling	KNTC1 ATM CCNB1	1.13e-04	51	38	3	GO:0007094
GeneOntologyBiologicalProcess	spindle assembly checkpoint signaling	KNTC1 ATM CCNB1	1.13e-04	51	38	3	GO:0071173
GeneOntologyBiologicalProcess	regulation of chromosome organization	KNTC1 ATM TENT4B ATR CCNB1	1.22e-04	266	38	5	GO:0033044
GeneOntologyBiologicalProcess	negative regulation of mitotic sister chromatid separation	KNTC1 ATM CCNB1	1.27e-04	53	38	3	GO:2000816
GeneOntologyBiologicalProcess	mitotic spindle checkpoint signaling	KNTC1 ATM CCNB1	1.27e-04	53	38	3	GO:0071174
GeneOntologyBiologicalProcess	negative regulation of mitotic metaphase/anaphase transition	KNTC1 ATM CCNB1	1.27e-04	53	38	3	GO:0045841
GeneOntologyBiologicalProcess	negative regulation of mitotic sister chromatid segregation	KNTC1 ATM CCNB1	1.27e-04	53	38	3	GO:0033048
GeneOntologyBiologicalProcess	negative regulation of sister chromatid segregation	KNTC1 ATM CCNB1	1.27e-04	53	38	3	GO:0033046
GeneOntologyBiologicalProcess	negative regulation of chromosome separation	KNTC1 ATM CCNB1	1.42e-04	55	38	3	GO:1905819
GeneOntologyBiologicalProcess	negative regulation of metaphase/anaphase transition of cell cycle	KNTC1 ATM CCNB1	1.42e-04	55	38	3	GO:1902100
GeneOntologyBiologicalProcess	spindle checkpoint signaling	KNTC1 ATM CCNB1	1.58e-04	57	38	3	GO:0031577
GeneOntologyBiologicalProcess	negative regulation of chromosome segregation	KNTC1 ATM CCNB1	1.58e-04	57	38	3	GO:0051985
GeneOntologyBiologicalProcess	regulation of telomere maintenance via telomerase	ATM TENT4B ATR	1.84e-04	60	38	3	GO:0032210
GeneOntologyBiologicalProcess	regulation of mitotic sister chromatid segregation	KNTC1 ATM CCNB1	1.84e-04	60	38	3	GO:0033047
GeneOntologyBiologicalProcess	negative regulation of mitotic nuclear division	KNTC1 ATM CCNB1	2.22e-04	64	38	3	GO:0045839
GeneOntologyBiologicalProcess	regulation of mitotic sister chromatid separation	KNTC1 ATM CCNB1	2.22e-04	64	38	3	GO:0010965
GeneOntologyBiologicalProcess	mitotic cell cycle checkpoint signaling	KNTC1 ATM ATR CCNB1	2.25e-04	163	38	4	GO:0007093
GeneOntologyBiologicalProcess	mitotic sister chromatid separation	KNTC1 ATM CCNB1	2.55e-04	67	38	3	GO:0051306
GeneOntologyBiologicalProcess	cell cycle G2/M phase transition	ATM ATR CCNB2 CCNB1	2.70e-04	171	38	4	GO:0044839
GeneOntologyBiologicalProcess	regulation of telomere maintenance via telomere lengthening	ATM TENT4B ATR	2.78e-04	69	38	3	GO:1904356
GeneOntologyBiologicalProcess	negative regulation of nuclear division	KNTC1 ATM CCNB1	3.28e-04	73	38	3	GO:0051784
GeneOntologyBiologicalProcess	histone mRNA catabolic process	ATM TENT4B	3.42e-04	15	38	2	GO:0071044
GeneOntologyBiologicalProcess	telomere maintenance via telomerase	ATM TENT4B ATR	3.84e-04	77	38	3	GO:0007004
GeneOntologyBiologicalProcess	replicative senescence	ATM ATR	3.90e-04	16	38	2	GO:0090399
GeneOntologyBiologicalProcess	regulation of cellular response to heat	ATM ATR	3.90e-04	16	38	2	GO:1900034
GeneOntologyBiologicalProcess	regulation of chromosome separation	KNTC1 ATM CCNB1	4.14e-04	79	38	3	GO:1905818
GeneOntologyBiologicalProcess	positive regulation of DNA damage response, signal transduction by p53 class mediator	ATM ATR	4.42e-04	17	38	2	GO:0043517
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	ATM TENT4B ATR	4.79e-04	83	38	3	GO:0006278
GeneOntologyBiologicalProcess	chromosome separation	KNTC1 ATM CCNB1	5.68e-04	88	38	3	GO:0051304
GeneOntologyBiologicalProcess	telomere maintenance via telomere lengthening	ATM TENT4B ATR	6.07e-04	90	38	3	GO:0010833
GeneOntologyBiologicalProcess	negative regulation of triglyceride metabolic process	GPLD1 CIDEC	6.15e-04	20	38	2	GO:0090209
GeneOntologyBiologicalProcess	cell cycle checkpoint signaling	KNTC1 ATM ATR CCNB1	6.65e-04	217	38	4	GO:0000075
GeneOntologyBiologicalProcess	cardiac muscle cell contraction	CACNA1C MYH7B SCN9A	6.68e-04	93	38	3	GO:0086003
GeneOntologyBiologicalProcess	negative regulation of mitotic cell cycle phase transition	KNTC1 ATM ATR CCNB1	6.88e-04	219	38	4	GO:1901991
GeneOntologyBiologicalProcess	regulation of mitotic metaphase/anaphase transition	KNTC1 ATM CCNB1	7.10e-04	95	38	3	GO:0030071
GeneOntologyBiologicalProcess	RNA 3'-end processing	CPSF1 TENT4B CCNB1	7.78e-04	98	38	3	GO:0031123
GeneOntologyBiologicalProcess	regulation of metaphase/anaphase transition of cell cycle	KNTC1 ATM CCNB1	7.78e-04	98	38	3	GO:1902099
GeneOntologyBiologicalProcess	clathrin coat assembly	AP1B1 AP2B1	8.16e-04	23	38	2	GO:0048268
GeneOntologyBiologicalProcess	metaphase/anaphase transition of mitotic cell cycle	KNTC1 ATM CCNB1	8.25e-04	100	38	3	GO:0007091
GeneOntologyBiologicalProcess	histone mRNA metabolic process	ATM TENT4B	8.89e-04	24	38	2	GO:0008334
GeneOntologyBiologicalProcess	regulation of attachment of spindle microtubules to kinetochore	KNTC1 CCNB1	8.89e-04	24	38	2	GO:0051988
GeneOntologyBiologicalProcess	metaphase/anaphase transition of cell cycle	KNTC1 ATM CCNB1	8.99e-04	103	38	3	GO:0044784
GeneOntologyBiologicalProcess	hormone secretion	GPLD1 CACNA1C KDM5B RAB1A ARHGEF7	9.86e-04	420	38	5	GO:0046879
GeneOntologyBiologicalProcess	substrate adhesion-dependent cell spreading	RAB1A ARHGEF7 ITGB7	1.06e-03	109	38	3	GO:0034446
GeneOntologyBiologicalProcess	regulation of sister chromatid segregation	KNTC1 ATM CCNB1	1.12e-03	111	38	3	GO:0033045
GeneOntologyBiologicalProcess	hormone transport	GPLD1 CACNA1C KDM5B RAB1A ARHGEF7	1.12e-03	432	38	5	GO:0009914
GeneOntologyBiologicalProcess	regulation of telomere maintenance	ATM TENT4B ATR	1.14e-03	112	38	3	GO:0032204
GeneOntologyBiologicalProcess	regulation of G2/M transition of mitotic cell cycle	ATM ATR CCNB1	1.27e-03	116	38	3	GO:0010389
GeneOntologyBiologicalProcess	cellular response to gamma radiation	ATM ATR	1.30e-03	29	38	2	GO:0071480
GeneOntologyBiologicalProcess	establishment of chromosome localization	KNTC1 ATM CCNB1	1.46e-03	122	38	3	GO:0051303
GeneOntologyBiologicalProcess	triglyceride metabolic process	GPLD1 TNXB CIDEC	1.64e-03	127	38	3	GO:0006641
GeneOntologyBiologicalProcess	actin-mediated cell contraction	CACNA1C MYH7B SCN9A	1.64e-03	127	38	3	GO:0070252
GeneOntologyBiologicalProcess	negative regulation of mitotic cell cycle	KNTC1 ATM ATR CCNB1	1.75e-03	282	38	4	GO:0045930
GeneOntologyBiologicalProcess	chromosome localization	KNTC1 ATM CCNB1	1.76e-03	130	38	3	GO:0050000
GeneOntologyBiologicalProcess	negative regulation of lipid catabolic process	GPLD1 CIDEC	1.79e-03	34	38	2	GO:0050995
GeneOntologyBiologicalProcess	positive regulation of signal transduction by p53 class mediator	ATM ATR	1.79e-03	34	38	2	GO:1901798
GeneOntologyBiologicalProcess	regulation of cell cycle G2/M phase transition	ATM ATR CCNB1	1.80e-03	131	38	3	GO:1902749
GeneOntologyBiologicalProcess	regulation of mitotic nuclear division	KNTC1 ATM CCNB1	1.92e-03	134	38	3	GO:0007088
GeneOntologyBiologicalProcess	post-embryonic development	KDM5B ATM SCN9A	1.96e-03	135	38	3	GO:0009791
GeneOntologyBiologicalProcess	positive regulation of telomere maintenance via telomerase	ATM ATR	2.00e-03	36	38	2	GO:0032212
GeneOntologyBiologicalProcess	membrane depolarization during action potential	CACNA1C SCN9A	2.00e-03	36	38	2	GO:0086010
GeneOntologyBiologicalProcess	regulation of DNA biosynthetic process	ATM TENT4B ATR	2.08e-03	138	38	3	GO:2000278
GeneOntologyBiologicalProcess	regulation of chromosome segregation	KNTC1 ATM CCNB1	2.13e-03	139	38	3	GO:0051983
GeneOntologyBiologicalProcess	mitotic cell cycle phase transition	KNTC1 ATM ATR CCNB2 CCNB1	2.30e-03	509	38	5	GO:0044772
GeneOntologyBiologicalProcess	positive regulation of telomere maintenance via telomere lengthening	ATM ATR	2.35e-03	39	38	2	GO:1904358
GeneOntologyBiologicalProcess	ribonucleoprotein complex biogenesis	NSUN4 EIF3C ATM TENT4B ATR	2.42e-03	515	38	5	GO:0022613
GeneOntologyBiologicalProcess	regulation of DNA damage response, signal transduction by p53 class mediator	ATM ATR	2.47e-03	40	38	2	GO:0043516
GeneOntologyBiologicalProcess	negative regulation of cell cycle phase transition	KNTC1 ATM ATR CCNB1	2.50e-03	311	38	4	GO:1901988
GeneOntologyBiologicalProcess	negative regulation of telomere maintenance	ATM TENT4B	2.72e-03	42	38	2	GO:0032205
GeneOntologyBiologicalProcess	G2/M transition of mitotic cell cycle	ATM ATR CCNB1	2.74e-03	152	38	3	GO:0000086
GeneOntologyBiologicalProcess	actin filament-based movement	CACNA1C MYH7B SCN9A	2.79e-03	153	38	3	GO:0030048
GeneOntologyBiologicalProcess	regulation of cardiac muscle cell contraction	CACNA1C MYH7B	2.85e-03	43	38	2	GO:0086004
GeneOntologyBiologicalProcess	negative regulation of DNA metabolic process	ATM TENT4B ATR	2.90e-03	155	38	3	GO:0051053
GeneOntologyBiologicalProcess	acylglycerol metabolic process	GPLD1 TNXB CIDEC	2.95e-03	156	38	3	GO:0006639
GeneOntologyBiologicalProcess	secretion by cell	GPLD1 CACNA1C KDM5B AP1B1 RAB1A ARHGEF7 TCP11	2.95e-03	1064	38	7	GO:0032940
GeneOntologyBiologicalProcess	positive regulation of peptide hormone secretion	GPLD1 CACNA1C ARHGEF7	3.00e-03	157	38	3	GO:0090277
GeneOntologyBiologicalProcess	neutral lipid metabolic process	GPLD1 TNXB CIDEC	3.06e-03	158	38	3	GO:0006638
GeneOntologyBiologicalProcess	positive regulation of peptide secretion	GPLD1 CACNA1C ARHGEF7	3.22e-03	161	38	3	GO:0002793
GeneOntologyBiologicalProcess	peptide hormone secretion	GPLD1 CACNA1C RAB1A ARHGEF7	3.23e-03	334	38	4	GO:0030072
GeneOntologyBiologicalProcess	mRNA 3'-end processing	TENT4B CCNB1	3.25e-03	46	38	2	GO:0031124
Domain	Clathrin_b-adaptin_app_Ig-like	AP1B1 AP2B1	3.61e-06	2	36	2	IPR013037
Domain	-	AP1B1 AP2B1	3.61e-06	2	36	2	2.60.40.1150
Domain	AP_complex_bsu_1_2_4	AP1B1 AP2B1	1.08e-05	3	36	2	IPR016342
Domain	B2-adapt-app_C	AP1B1 AP2B1	1.08e-05	3	36	2	PF09066
Domain	B-adaptin_app_sub_C	AP1B1 AP2B1	2.16e-05	4	36	2	IPR015151
Domain	B2-adapt-app_C	AP1B1 AP2B1	2.16e-05	4	36	2	SM01020
Domain	FATC	ATM ATR	3.60e-05	5	36	2	PF02260
Domain	AP_beta	AP1B1 AP2B1	3.60e-05	5	36	2	IPR026739
Domain	FAT	ATM ATR	5.39e-05	6	36	2	PF02259
Domain	PIK-rel_kinase_FAT	ATM ATR	5.39e-05	6	36	2	IPR003151
Domain	FATC_dom	ATM ATR	5.39e-05	6	36	2	IPR003152
Domain	PIK_FAT	ATM ATR	5.39e-05	6	36	2	IPR014009
Domain	FAT	ATM ATR	5.39e-05	6	36	2	PS51189
Domain	FATC	ATM ATR	5.39e-05	6	36	2	PS51190
Domain	Beta2_adaptin/TBP_C_dom	AP1B1 AP2B1	5.39e-05	6	36	2	IPR012295
Domain	FATC	ATM ATR	5.39e-05	6	36	2	SM01343
Domain	-	AP1B1 AP2B1	5.39e-05	6	36	2	3.30.310.10
Domain	Coatomer/calthrin_app_sub_C	AP1B1 AP2B1	1.00e-04	8	36	2	IPR009028
Domain	Clathrin_a/b/g-adaptin_app_Ig	AP1B1 AP2B1	1.29e-04	9	36	2	IPR008152
Domain	Alpha_adaptinC2	AP1B1 AP2B1	1.29e-04	9	36	2	PF02883
Domain	Alpha_adaptinC2	AP1B1 AP2B1	1.29e-04	9	36	2	SM00809
Domain	ARM-like	DOCK10 HUWE1 ATR AP1B1 AP2B1	1.59e-04	270	36	5	IPR011989
Domain	Coatomer/clathrin_app_Ig-like	AP1B1 AP2B1	2.36e-04	12	36	2	IPR013041
Domain	Clathrin/coatomer_adapt-like_N	AP1B1 AP2B1	3.73e-04	15	36	2	IPR002553
Domain	Adaptin_N	AP1B1 AP2B1	3.73e-04	15	36	2	PF01602
Domain	PI3/4_kinase_CS	ATM ATR	3.73e-04	15	36	2	IPR018936
Domain	PI3Kc	ATM ATR	4.26e-04	16	36	2	SM00146
Domain	-	ATM ATR	4.26e-04	16	36	2	1.10.1070.11
Domain	ARM-type_fold	ATM HUWE1 ATR AP1B1 AP2B1	4.54e-04	339	36	5	IPR016024
Domain	Cyclin_C-dom	CCNB2 CCNB1	4.82e-04	17	36	2	IPR004367
Domain	Cyclin_C	CCNB2 CCNB1	4.82e-04	17	36	2	PF02984
Domain	Cyclin_C	CCNB2 CCNB1	4.82e-04	17	36	2	SM01332
Domain	PI3_4_KINASE_1	ATM ATR	5.42e-04	18	36	2	PS00915
Domain	PI3_4_KINASE_2	ATM ATR	5.42e-04	18	36	2	PS00916
Domain	PI3/4_kinase_cat_dom	ATM ATR	5.42e-04	18	36	2	IPR000403
Domain	PI3_PI4_kinase	ATM ATR	5.42e-04	18	36	2	PF00454
Domain	PI3_4_KINASE_3	ATM ATR	5.42e-04	18	36	2	PS50290
Domain	CYCLINS	CCNB2 CCNB1	1.32e-03	28	36	2	PS00292
Domain	Cyclin_N	CCNB2 CCNB1	1.84e-03	33	36	2	IPR006671
Domain	Cyclin_N	CCNB2 CCNB1	1.84e-03	33	36	2	PF00134
Domain	CYCLIN	CCNB2 CCNB1	2.43e-03	38	36	2	SM00385
Domain	-	CCNB2 CCNB1	2.69e-03	40	36	2	1.10.472.10
Domain	ARM	AP1B1 AP2B1	2.69e-03	40	36	2	SM00185
Domain	Cyclin-like	CCNB2 CCNB1	3.10e-03	43	36	2	IPR013763
Domain	Armadillo	AP1B1 AP2B1	3.70e-03	47	36	2	IPR000225
Domain	Channel_four-helix_dom	CACNA1C SCN9A	5.39e-03	57	36	2	IPR027359
Domain	-	CACNA1C SCN9A	5.39e-03	57	36	2	1.20.120.350
Domain	EGF_extracell	TNXB ITGB7	5.96e-03	60	36	2	IPR013111
Domain	EGF_2	TNXB ITGB7	5.96e-03	60	36	2	PF07974
Domain	Zinc_finger_PHD-type_CS	KDM5B ING3	6.96e-03	65	36	2	IPR019786
Domain	-	ATR AP1B1 AP2B1	8.86e-03	222	36	3	1.25.10.10
Domain	PHD	KDM5B ING3	9.18e-03	75	36	2	PF00628
Pathway	KEGG_MEDICUS_REFERENCE_ATR_P21_CELL_CYCLE_G2_M	ATM ATR CCNB2 CCNB1	2.39e-09	9	31	4	M47586
Pathway	KEGG_MEDICUS_REFERENCE_CDC25_CELL_CYCLE_G2_M	ATM ATR CCNB2 CCNB1	3.98e-09	10	31	4	M47572
Pathway	KEGG_MEDICUS_REFERENCE_WEE1_CELL_CYCLE_G2_M	ATR CCNB2 CCNB1	3.35e-07	7	31	3	M47574
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_CDC25_CELL_CYCLE_G2M	ATR CCNB2 CCNB1	1.57e-06	11	31	3	M47573
Pathway	REACTOME_GOLGI_CISTERNAE_PERICENTRIOLAR_STACK_REORGANIZATION	RAB1A CCNB2 CCNB1	3.45e-06	14	31	3	M26983
Pathway	WP_P53_SIGNALING	ATM ATR CCNB2 CCNB1	1.18e-05	65	31	4	MM15852
Pathway	KEGG_P53_SIGNALING_PATHWAY	ATM ATR CCNB2 CCNB1	1.41e-05	68	31	4	M6370
Pathway	WP_DNA_DAMAGE_RESPONSE	ATM ATR CCNB2 CCNB1	1.50e-05	69	31	4	M39339
Pathway	BIOCARTA_G2_PATHWAY	ATM ATR CCNB1	1.89e-05	24	31	3	M8560
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_WEE1_CELL_CYCLE_G2M	CCNB2 CCNB1	4.66e-05	5	31	2	M49022
Pathway	REACTOME_ACTIVATION_OF_NIMA_KINASES_NEK9_NEK6_NEK7	CCNB2 CCNB1	4.66e-05	5	31	2	MM14918
Pathway	REACTOME_G2_M_DNA_REPLICATION_CHECKPOINT	CCNB2 CCNB1	4.66e-05	5	31	2	M27669
Pathway	REACTOME_G2_M_DNA_REPLICATION_CHECKPOINT	CCNB2 CCNB1	4.66e-05	5	31	2	MM15382
Pathway	WP_MIRNA_REGULATION_OF_DNA_DAMAGE_RESPONSE	ATM ATR CCNB2 CCNB1	5.98e-05	98	31	4	M39524
Pathway	REACTOME_ACTIVATION_OF_NIMA_KINASES_NEK9_NEK6_NEK7	CCNB2 CCNB1	9.76e-05	7	31	2	M27213
Pathway	BIOCARTA_PLK3_PATHWAY	ATM ATR	1.30e-04	8	31	2	M22021
Pathway	WP_NIPBL_ROLE_IN_DNA_DAMAGE_CORNELIA_DE_LANGE_SYNDROME	ATM ATR	1.30e-04	8	31	2	M42528
Pathway	WP_CELL_CYCLE	ATM ATR CCNB2 CCNB1	1.32e-04	120	31	4	M39650
Pathway	KEGG_CELL_CYCLE	ATM ATR CCNB2 CCNB1	1.54e-04	125	31	4	M7963
Pathway	REACTOME_CONDENSATION_OF_PROMETAPHASE_CHROMOSOMES	CCNB2 CCNB1	2.54e-04	11	31	2	M27182
Pathway	PID_P53_REGULATION_PATHWAY	ATM HUWE1 ATR	2.88e-04	59	31	3	M261
Pathway	BIOCARTA_EFP_PATHWAY	CCNB2 CCNB1	3.60e-04	13	31	2	MM1537
Pathway	REACTOME_CELL_CYCLE_CHECKPOINTS	KNTC1 ATM ATR CCNB2 CCNB1	3.96e-04	291	31	5	M16647
Pathway	REACTOME_G2_M_CHECKPOINTS	ATM ATR CCNB2 CCNB1	4.66e-04	167	31	4	M19381
Pathway	KEGG_MEDICUS_REFERENCE_P300_P21_CELL_CYCLE_G1_S	ATM ATR	4.83e-04	15	31	2	M47524
Pathway	REACTOME_POLO_LIKE_KINASE_MEDIATED_EVENTS	CCNB2 CCNB1	5.51e-04	16	31	2	M26971
Pathway	BIOCARTA_EFP_PATHWAY	CCNB2 CCNB1	5.51e-04	16	31	2	M22011
Pathway	REACTOME_INITIATION_OF_NUCLEAR_ENVELOPE_NE_REFORMATION	CCNB2 CCNB1	6.24e-04	17	31	2	MM14920
Pathway	REACTOME_INITIATION_OF_NUCLEAR_ENVELOPE_NE_REFORMATION	CCNB2 CCNB1	7.82e-04	19	31	2	M29617
Pathway	REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS	AP1B1 AP2B1	9.58e-04	21	31	2	M12347
Pathway	BIOCARTA_ATRBRCA_PATHWAY	ATM ATR	1.05e-03	22	31	2	M9703
Pathway	BIOCARTA_G2_PATHWAY	ATR CCNB1	1.05e-03	22	31	2	MM1365
Pathway	REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT	ATM ATR CCNB1	1.13e-03	94	31	3	M1080
Pathway	REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	CCNB2 CCNB1	1.36e-03	25	31	2	MM15379
Pathway	REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	CCNB2 CCNB1	1.36e-03	25	31	2	M808
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY	ARHGEF7 ITGB7	1.47e-03	26	31	2	M47719
Pathway	REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS	AP1B1 AP2B1	1.71e-03	28	31	2	M11362
Pathway	BIOCARTA_G1_PATHWAY	ATM ATR	1.71e-03	28	31	2	M648
Pathway	PID_BARD1_PATHWAY	ATM ATR	1.83e-03	29	31	2	M258
Pathway	PID_CDC42_REG_PATHWAY	DOCK10 ARHGEF7	1.96e-03	30	31	2	M83
Pathway	REACTOME_MITOTIC_PROPHASE	RAB1A CCNB2 CCNB1	1.96e-03	114	31	3	MM15361
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	CACNA1C SCN9A	2.23e-03	32	31	2	M27455
Pathway	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE	SLC6A15 SLC7A2	2.37e-03	33	31	2	M188
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	KNTC1 CCNB2 CCNB1	2.67e-03	127	31	3	M27181
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	KNTC1 CCNB2 CCNB1	2.79e-03	129	31	3	MM14894
Pathway	REACTOME_CELL_CYCLE_CHECKPOINTS	KNTC1 ATM CCNB2 CCNB1	2.79e-03	271	31	4	MM15388
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	CCNB2 CCNB1	2.81e-03	36	31	2	M27245
Pathway	REACTOME_HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA	ATM ATR	2.97e-03	37	31	2	M27568
Pathway	WP_ATM_SIGNALING	ATM CCNB1	3.47e-03	40	31	2	M39433
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	CCNB2 CCNB1	3.47e-03	40	31	2	MM14945
Pathway	PID_FOXM1_PATHWAY	CCNB2 CCNB1	3.47e-03	40	31	2	M176
Pathway	REACTOME_CELL_CYCLE	KNTC1 ATM ATR RAB1A CCNB2 CCNB1	3.57e-03	694	31	6	M543
Pathway	REACTOME_MITOTIC_PROPHASE	RAB1A CCNB2 CCNB1	3.66e-03	142	31	3	M27660
Pathway	REACTOME_G2_M_CHECKPOINTS	ATM CCNB2 CCNB1	3.73e-03	143	31	3	MM15383
Pathway	REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE	ATM ATR	4.00e-03	43	31	2	M27588
Pathway	PID_PLK1_PATHWAY	RAB1A CCNB1	4.56e-03	46	31	2	M129
Pathway	PID_DELTA_NP63_PATHWAY	ATM CCNB2	4.76e-03	47	31	2	M236
Pathway	WP_ATM_SIGNALING_IN_DEVELOPMENT_AND_DISEASE	ATM ATR	4.76e-03	47	31	2	M39518
Pathway	PID_FANCONI_PATHWAY	ATM ATR	4.76e-03	47	31	2	M1
Pubmed	ATM binds to beta-adaptin in cytoplasmic vesicles.	ATM AP1B1 AP2B1	5.21e-09	4	39	3	9707615
Pubmed	A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.	ATM HUWE1 ATR	1.56e-07	10	39	3	17478428
Pubmed	Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons.	ATM ATR CCNB2 CCNB1	6.73e-07	61	39	4	34746147
Pubmed	Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences.	SLC7A2 CCNB2 CCNB1	1.05e-06	18	39	3	1387105
Pubmed	Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks.	ATM ATR	1.23e-06	2	39	2	19285939
Pubmed	DNA damage-sensing kinases mediate the mouse 2-cell embryo's response to genotoxic stress.	ATM ATR	1.23e-06	2	39	2	21593482
Pubmed	A synthetic lethal screen reveals enhanced sensitivity to ATR inhibitor treatment in mantle cell lymphoma with ATM loss-of-function.	ATM ATR	1.23e-06	2	39	2	25232030
Pubmed	Expression variations of DNA damage response genes ATM and ATR in blood cancer patients.	ATM ATR	1.23e-06	2	39	2	37338595
Pubmed	DNA damage induces a kinetochore-based ATM/ATR-independent SAC arrest unique to the first meiotic division in mouse oocytes.	ATM ATR	1.23e-06	2	39	2	28851706
Pubmed	ATM acts downstream of ATR in the DNA damage response signaling of bystander cells.	ATM ATR	1.23e-06	2	39	2	18757420
Pubmed	Cellular responses to the DNA strand-scission enediyne C-1027 can be independent of ATM, ATR, and DNA-PK kinases.	ATM ATR	1.23e-06	2	39	2	11927575
Pubmed	In Vivo and In Vitro Effects of ATM/ATR Signaling Pathway on Proliferation, Apoptosis, and Radiosensitivity of Nasopharyngeal Carcinoma Cells.	ATM ATR	1.23e-06	2	39	2	28820634
Pubmed	ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations.	ATM ATR	1.23e-06	2	39	2	29279380
Pubmed	ATR regulates fragile site stability.	ATM ATR	1.23e-06	2	39	2	12526805
Pubmed	Isolation of the murine cyclin B2 cDNA and characterization of the lineage and temporal specificity of expression of the B1 and B2 cyclins during oogenesis, spermatogenesis and early embryogenesis.	CCNB2 CCNB1	1.23e-06	2	39	2	8375336
Pubmed	The kinetics of G2 and M transitions regulated by B cyclins.	CCNB2 CCNB1	1.23e-06	2	39	2	24324638
Pubmed	Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM).	ATM ATR	1.23e-06	2	39	2	34151669
Pubmed	Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome.	ATM ATR	1.23e-06	2	39	2	16213462
Pubmed	ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle.	ATM ATR	1.23e-06	2	39	2	27442013
Pubmed	Induction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhances cytotoxicity of ovarian cancer cells.	ATM ATR	1.23e-06	2	39	2	24726882
Pubmed	5'-UTR and ORF elements, as well as the 3'-UTR regulate the translation of Cyclin.	CCNB2 CCNB1	1.23e-06	2	39	2	32439164
Pubmed	Investigation of switch from ATM to ATR signaling at the sites of DNA damage induced by low and high LET radiation.	ATM ATR	1.23e-06	2	39	2	24238855
Pubmed	Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex.	ATM ATR	1.23e-06	2	39	2	16474843
Pubmed	The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle.	CCNB2 CCNB1	1.23e-06	2	39	2	29074977
Pubmed	The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.	ATM ATR	1.23e-06	2	39	2	8843195
Pubmed	rRNA synthesis inhibitor, CX-5461, activates ATM/ATR pathway in acute lymphoblastic leukemia, arrests cells in G2 phase and induces apoptosis.	ATM ATR	1.23e-06	2	39	2	26061708
Pubmed	Viral DNA replication-dependent DNA damage response activation during BK polyomavirus infection.	ATM ATR	1.23e-06	2	39	2	25694603
Pubmed	Ataxia-Telangiectasia and RAD3-Related and Ataxia-Telangiectasia-Mutated Proteins in Epithelial Ovarian Carcinoma: Their Expression and Clinical Significance.	ATM ATR	1.23e-06	2	39	2	26124337
Pubmed	Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces G₂/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells.	ATM ATR	1.23e-06	2	39	2	25812484
Pubmed	Roles of ATM and ATR-mediated DNA damage responses during lytic BK polyomavirus infection.	ATM ATR	1.23e-06	2	39	2	22952448
Pubmed	Functional significance for a heterogenous ribonucleoprotein A18 signature RNA motif in the 3'-untranslated region of ataxia telangiectasia mutated and Rad3-related (ATR) transcript.	ATM ATR	1.23e-06	2	39	2	20103595
Pubmed	ATM regulates ATR chromatin loading in response to DNA double-strand breaks.	ATM ATR	1.23e-06	2	39	2	16461339
Pubmed	Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis.	CCNB2 CCNB1	1.23e-06	2	39	2	29074707
Pubmed	ATR localizes to the photoreceptor connecting cilium and deficiency leads to severe photoreceptor degeneration in mice.	ATM ATR	1.23e-06	2	39	2	23297361
Pubmed	Interplay between ATM and ATR in the regulation of common fragile site stability.	ATM ATR	1.23e-06	2	39	2	17934520
Pubmed	Inactivation of ATM/ATR DNA damage checkpoint promotes androgen induced chromosomal instability in prostate epithelial cells.	ATM ATR	1.23e-06	2	39	2	23272087
Pubmed	Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents.	ATM ATR	1.23e-06	2	39	2	25483091
Pubmed	ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication.	ATM ATR	1.23e-06	2	39	2	23592994
Pubmed	The Dimeric Architecture of Checkpoint Kinases Mec1ATR and Tel1ATM Reveal a Common Structural Organization.	ATM ATR	1.23e-06	2	39	2	27129217
Pubmed	Bleomycin-induced over-replication involves sustained inhibition of mitotic entry through the ATM/ATR pathway.	ATM ATR	1.23e-06	2	39	2	19527713
Pubmed	Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants.	ATM ATR	1.23e-06	2	39	2	20368801
Pubmed	Clinicopathological significance of ataxia telangiectasia-mutated (ATM) kinase and ataxia telangiectasia-mutated and Rad3-related (ATR) kinase in MYC overexpressed breast cancers.	ATM ATR	1.23e-06	2	39	2	30746633
Pubmed	Proficiency in homologous recombination repair is prerequisite for activation of G2-checkpoint at low radiation doses.	ATM ATR	1.23e-06	2	39	2	33640756
Pubmed	A role for ATR in the DNA damage-induced phosphorylation of p53.	ATM ATR	1.23e-06	2	39	2	9925639
Pubmed	Analysis of mutations that dissociate G(2) and essential S phase functions of human ataxia telangiectasia-mutated and Rad3-related (ATR) protein kinase.	ATM ATR	1.23e-06	2	39	2	21908846
Pubmed	ATM and ATR signaling at a glance.	ATM ATR	1.23e-06	2	39	2	26567218
Pubmed	The ATM and Rad3-Related (ATR) Protein Kinase Pathway Is Activated by Herpes Simplex Virus 1 and Required for Efficient Viral Replication.	ATM ATR	1.23e-06	2	39	2	29263259
Pubmed	Cyclin B2 can compensate for Cyclin B1 in oocyte meiosis I.	CCNB2 CCNB1	1.23e-06	2	39	2	30097513
Pubmed	An S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control.	ATM ATR	1.23e-06	2	39	2	23176708
Pubmed	The ATM- and ATR-related SCD domain is over-represented in proteins involved in nervous system development.	ATM ATR	1.23e-06	2	39	2	26743489
Pubmed	Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage.	ATM ATR	1.23e-06	2	39	2	15533933
Pubmed	ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling.	ATM ATR	1.23e-06	2	39	2	17124492
Pubmed	Cancer genome datamining and functional genetic analysis implicate mechanisms of ATM/ATR dysfunction underpinning carcinogenesis.	ATM ATR	1.23e-06	2	39	2	33742106
Pubmed	Roles of ATM and ATR in DNA double strand breaks and replication stress.	ATM ATR	1.23e-06	2	39	2	33887296
Pubmed	ATR disruption leads to chromosomal fragmentation and early embryonic lethality.	ATM ATR	1.23e-06	2	39	2	10691732
Pubmed	ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation.	ATM ATR	1.23e-06	2	39	2	12519769
Pubmed	Cyclin B2 suppresses mitotic failure and DNA re-replication in human somatic cells knocked down for both cyclins B1 and B2.	CCNB2 CCNB1	1.23e-06	2	39	2	17533373
Pubmed	Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription.	ATM ATR	1.23e-06	2	39	2	31114877
Pubmed	Prognostic value of cyclin B1 and cyclin B2 expression in breast cancer: A systematic review and updated meta-analysis.	CCNB2 CCNB1	1.23e-06	2	39	2	38241547
Pubmed	Shift in G1-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation.	ATM ATR	1.23e-06	2	39	2	35011623
Pubmed	Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero.	CCNB2 CCNB1	1.23e-06	2	39	2	9539739
Pubmed	The association of ATR protein with mouse meiotic chromosome cores.	ATM ATR	1.23e-06	2	39	2	10382071
Pubmed	Overexpression of B-type cyclins alters chromosomal segregation.	CCNB2 CCNB1	1.23e-06	2	39	2	11960377
Pubmed	The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo.	ATM ATR	1.23e-06	2	39	2	26517239
Pubmed	Substrate specificities and identification of putative substrates of ATM kinase family members.	ATM ATR AP1B1	2.95e-06	25	39	3	10608806
Pubmed	ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells.	ATM ATR	3.67e-06	3	39	2	26563132
Pubmed	ATR/ATM-Mediated Phosphorylation of BRCA1 T1394 Promotes Homologous Recombinational Repair and G2-M Checkpoint Maintenance.	ATM ATR	3.67e-06	3	39	2	34301763
Pubmed	Profiling cancer gene mutations in longitudinal epithelial ovarian cancer biopsies by targeted next-generation sequencing: a retrospective study.	ATM ATR	3.67e-06	3	39	2	25846551
Pubmed	Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport.	CCNB2 CCNB1	3.67e-06	3	39	2	1717476
Pubmed	The ATM and ATR kinases regulate centrosome clustering and tumor recurrence by targeting KIFC1 phosphorylation.	ATM ATR	3.67e-06	3	39	2	33397932
Pubmed	ATM- and ATR-mediated phosphorylation of XRCC3 regulates DNA double-strand break-induced checkpoint activation and repair.	ATM ATR	3.67e-06	3	39	2	23438602
Pubmed	DNA damage-induced ATM- and Rad-3-related (ATR) kinase activation in non-replicating cells is regulated by the XPB subunit of transcription factor IIH (TFIIH).	ATM ATR	3.67e-06	3	39	2	28592488
Pubmed	Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation.	ATM ATR	3.67e-06	3	39	2	18344416
Pubmed	Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.	ATM ATR	3.67e-06	3	39	2	9766667
Pubmed	ATR dependent activation of Chk2.	ATM ATR	3.67e-06	3	39	2	16741947
Pubmed	Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.	ATM ATR	3.67e-06	3	39	2	27625305
Pubmed	Tagging single nucleotide polymorphisms in phosphoinositide-3-kinase-related protein kinase genes involved in DNA damage "checkpoints" and lung cancer susceptibility.	ATM ATR	3.67e-06	3	39	2	18451257
Pubmed	A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein.	ATM ATR	3.67e-06	3	39	2	12773400
Pubmed	Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase.	ATM ATR	3.67e-06	3	39	2	21844338
Pubmed	Key mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes.	ATM ATR	3.67e-06	3	39	2	26209650
Pubmed	Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance.	ATM ATR	3.67e-06	3	39	2	16943440
Pubmed	DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells.	ATM ATR	3.67e-06	3	39	2	27733644
Pubmed	Age-related decline in the expression of BRG1, ATM and ATR are partially reversed by dietary restriction in the livers of female mice.	ATM ATR	3.67e-06	3	39	2	38970714
Pubmed	The ATM/ATR signaling effector Chk2 is targeted by Epstein-Barr virus nuclear antigen 3C to release the G2/M cell cycle block.	ATM ATR	3.67e-06	3	39	2	17409144
Pubmed	Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.	ATM ATR	3.67e-06	3	39	2	11114888
Pubmed	CDK1, CCNB1, and CCNB2 are Prognostic Biomarkers and Correlated with Immune Infiltration in Hepatocellular Carcinoma.	CCNB2 CCNB1	3.67e-06	3	39	2	32863381
Pubmed	Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells.	ATM ATR	3.67e-06	3	39	2	19444312
Pubmed	The alkylating carcinogen N-methyl-N'-nitro-N-nitrosoguanidine activates the plasminogen activator inhibitor-1 gene through sequential phosphorylation of p53 by ATM and ATR kinases.	ATM ATR	3.67e-06	3	39	2	15735814
Pubmed	DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells.	ATM ATR	3.67e-06	3	39	2	31601897
Pubmed	ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres.	ATM ATR	3.67e-06	3	39	2	22842784
Pubmed	Activation of the ATM kinase by ionizing radiation and phosphorylation of p53.	ATM ATR	3.67e-06	3	39	2	9733515
Pubmed	IGF-1R inhibition sensitizes breast cancer cells to ATM-related kinase (ATR) inhibitor and cisplatin.	ATM ATR	3.67e-06	3	39	2	27472395
Pubmed	Human cyclins B1 and B2 are localized to strikingly different structures: B1 to microtubules, B2 primarily to the Golgi apparatus.	CCNB2 CCNB1	3.67e-06	3	39	2	7737117
Pubmed	A role for proapoptotic BID in the DNA-damage response.	ATM ATR	3.67e-06	3	39	2	16122425
Pubmed	Proapoptotic BID is an ATM effector in the DNA-damage response.	ATM ATR	3.67e-06	3	39	2	16122426
Pubmed	ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells.	ATM ATR	3.67e-06	3	39	2	26586427
Pubmed	The roles of cyclin A2, B1, and B2 in early and late mitotic events.	CCNB2 CCNB1	3.67e-06	3	39	2	20660152
Pubmed	Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase.	ATM ATR	3.67e-06	3	39	2	31164689
Pubmed	Rapid activation of ATR by ionizing radiation requires ATM and Mre11.	ATM ATR	3.67e-06	3	39	2	16431910
Pubmed	Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies.	ATM ATR	3.67e-06	3	39	2	11278964
GeneFamily	Cyclins	CCNB2 CCNB1	5.24e-04	28	22	2	473
GeneFamily	PHD finger proteins	KDM5B ING3	5.31e-03	90	22	2	88
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	DOCK10 ARHGEF7	2.57e-02	206	22	2	682
Coexpression	GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_UP	DOCK10 KNTC1 ARHGEF7 CCNB2 ITGB7	1.01e-05	200	38	5	M8075
Coexpression	ZERBINI_RESPONSE_TO_SULINDAC_DN	CCNB2 CCNB1	3.06e-05	6	38	2	M17956
Coexpression	PUJANA_BRCA2_PCC_NETWORK	CPSF1 KNTC1 ATR ARHGEF7 CCNB2 CCNB1	3.16e-05	426	38	6	M9516
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 SLC7A2 CCNB2 CIDEC CCNB1	7.42e-07	195	39	5	c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KNTC1 CCNB2 ITGB7 CCNB1	1.27e-05	164	39	4	e5258efd6765acfc394708f697ec76acaef09079
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK10 SLC7A2 CCNB2 CIDEC	1.49e-05	171	39	4	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	P28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KNTC1 SLC6A15 CCNB2 CCNB1	1.87e-05	181	39	4	e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCell	P28-Endothelial-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KNTC1 SLC6A15 CCNB2 CCNB1	1.87e-05	181	39	4	2be3d44619adb25d339e7a27b500a56e07e8de01
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 SLC7A2 MYH7B CIDEC	1.95e-05	183	39	4	42dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 CCNB2 CIDEC CCNB1	1.95e-05	183	39	4	e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC7A2 CCNB2 CIDEC CCNB1	2.03e-05	185	39	4	57c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C SLC7A2 TNXB	1.78e-04	125	39	3	b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCell	LV-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	CACNA1C MYH7B ITGB7	2.00e-04	130	39	3	a3e12984fb61311e49cc76c59f74f4dffc48faa1
ToppCell	Lymphoid-T_cells_(cycle)\|World / shred on cell class and cell subclass (v4)	CCNB2 ITGB7 CCNB1	2.64e-04	143	39	3	2fbcca395971a8452f68481282a74cec4005d1e2
ToppCell	LA-15._Ventricular_Cardiomyocyte_III\|LA / Chamber and Cluster_Paper	CACNA1C MYH7B ITGB7	2.86e-04	147	39	3	8970eb6b82589f39439c61a57d999661ec8342de
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GVINP1 TCP11 ITGB7	2.98e-04	149	39	3	48fca6ae33d7722c024b43ce04f4dbce7b6b424b
ToppCell	droplet-Lung-nan-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 SLC7A2 CIDEC	3.10e-04	151	39	3	c743dc8758416a4f562d60c8fd2df7e659ab6951
ToppCell	PND01-03-samps-Myeloid-Macrophage-macrophage-B\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	KNTC1 CIDEC CCNB1	3.16e-04	152	39	3	5ce8920aedd39a4daf7082153b5e213707c14227
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCNB2 ITGB7 CCNB1	3.22e-04	153	39	3	c4dcdcaa672929c1da870e9fb8ada1bb030ad12f
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KNTC1 CCNB2 CCNB1	3.22e-04	153	39	3	d7635f3d4831c02a94f53afc674847d5b51453be
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KNTC1 CCNB2 CCNB1	3.22e-04	153	39	3	e50d20f9e553b8c3e10e187770d8abe1a43d109e
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KNTC1 CCNB2 CCNB1	3.22e-04	153	39	3	54a941950bbb848077c7bd5726da9e4b3244bd38
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P4\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KNTC1 CCNB2 CCNB1	3.22e-04	153	39	3	69a8550418ba0fc908a84b3b85761abb6e8ca4c0
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 SLC7A2 CIDEC	3.28e-04	154	39	3	a5289000597068ee8d559f89bce7bce31f35dd57
ToppCell	PND07-28-samps\|World / Age Group, Lineage, Cell class and subclass	DOCK10 GVINP1 CIDEC	3.47e-04	157	39	3	a2005768a6d268879e3fd6dbd8cf674dc98be587
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SLC7A2 CIDEC SCN9A	3.60e-04	159	39	3	f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SLC7A2 CIDEC SCN9A	3.60e-04	159	39	3	929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	DOCK10 CACNA1C ARHGEF7	3.67e-04	160	39	3	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	PND07-28-samps-Myeloid-Macrophage-macrophage-B\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DOCK10 SLC7A2 CIDEC	3.67e-04	160	39	3	694bf1f1952bd8ab444819f533da24fa2b73f701
ToppCell	PND01-03-samps-Myeloid-Macrophage-CD163+_Macrophage\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	AP1B1 CCNB2 CCNB1	3.67e-04	160	39	3	4480a7d6bd48d06b4e5196faac868f31ab7ed3ad
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KNTC1 CCNB2 CCNB1	3.74e-04	161	39	3	0dd1401b4c990d49fccb702a9f9867590a58e203
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-DC3\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CCNB2 ITGB7 CCNB1	3.74e-04	161	39	3	39030380e04f57f8e7de231577ec3177e1b6490d
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KNTC1 CCNB2 CCNB1	3.74e-04	161	39	3	b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	DOCK10 CACNA1C ARHGEF7	3.74e-04	161	39	3	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KNTC1 CCNB2 CCNB1	3.74e-04	161	39	3	efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	KNTC1 CCNB2 CCNB1	3.74e-04	161	39	3	28d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCell	PND07-28-samps-Myeloid-Macrophage\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DOCK10 SLC7A2 CIDEC	3.81e-04	162	39	3	7c73fe8388af370461e04097cf145cbc9847285b
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KNTC1 CCNB2 CCNB1	3.88e-04	163	39	3	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 CCNB2 CCNB1	3.95e-04	164	39	3	ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCell	PND01-03-samps-Myeloid-Macrophage\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	DOCK10 SLC7A2 CIDEC	3.95e-04	164	39	3	49733a9d3d95f05056b5b01916060ff20a8de3cf
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNB2 ITGB7 CCNB1	4.02e-04	165	39	3	26c750f10f6401752e2e63d91dc844c81b29d735
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 CCNB2 CCNB1	4.02e-04	165	39	3	a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCell	droplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 CCNB2 CCNB1	4.02e-04	165	39	3	96f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 CCNB2 CCNB1	4.16e-04	167	39	3	50c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 CCNB2 CCNB1	4.16e-04	167	39	3	1bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCell	PND07-28-samps-Myeloid\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DOCK10 SLC7A2 CIDEC	4.23e-04	168	39	3	87512f9e5e95333e7ffc6efa1e93bab2ba9154c6
ToppCell	facs-Marrow-T-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GVINP1 CCNB2 CCNB1	4.31e-04	169	39	3	1558606be0a8bcd4fd0ce609701a1411e4ca2f9f
ToppCell	facs-Marrow-T-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GVINP1 CCNB2 CCNB1	4.31e-04	169	39	3	1b2354de1ce4080118d9f01e7c5fd6079e705125
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK10 CACNA1C SLC7A2	4.38e-04	170	39	3	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KNTC1 CCNB2 ITGB7	4.38e-04	170	39	3	6b91d4cbe0697b65bfb2e099e7a9b39ea2fba3a9
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNB2 ITGB7 CCNB1	4.38e-04	170	39	3	da4dde7d0491ccc298cec7474a6a76ff3db36a4c
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNB2 ITGB7 CCNB1	4.38e-04	170	39	3	b04e2f84024baaae9b4ff19bdac8c69afdb92a76
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 CCNB2 CCNB1	4.46e-04	171	39	3	4ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	DOCK10 CACNA1C ARHGEF7	4.46e-04	171	39	3	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	10x3'2.3-week_17-19-Myeloid_DC-DC-tDC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ITGB7 CIDEC SCN9A	4.46e-04	171	39	3	b327fb7813a3cdae06c8a4f8a0c256e9a20132f6
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNB2 ITGB7 CCNB1	4.53e-04	172	39	3	282017db72d0537ac82aecc69393ccde9590be60
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 CCNB2 CCNB1	4.53e-04	172	39	3	35c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNB2 ITGB7 CCNB1	4.53e-04	172	39	3	4bdcf1ae2a1cfba0272c54072e37fb7958904321
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	HNMT CCNB2 CCNB1	4.61e-04	173	39	3	783b8fa08b9d8f597f251793eae164151662f1f9
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 SLC7A2 SCN9A	4.61e-04	173	39	3	61907116a1460bc157ba73b5edd108db7dd5de4b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 CCNB2 CCNB1	4.69e-04	174	39	3	84da9faff088d05233183b425385beb054c92d1b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 CCNB2 CCNB1	4.69e-04	174	39	3	dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell	COVID-19-Heart-VSMC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C SLC7A2 ARHGEF7	4.77e-04	175	39	3	1125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 CCNB2 CCNB1	4.77e-04	175	39	3	0b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNB2 ITGB7 CCNB1	4.77e-04	175	39	3	ae7e0448ffd11b8908d0f6d99ff737faf5eca4bf
ToppCell	Club-club-15\|World / Class top	CCNB2 CWF19L1 CCNB1	4.77e-04	175	39	3	ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 CCNB2 CCNB1	4.77e-04	175	39	3	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNB2 ITGB7 CCNB1	4.77e-04	175	39	3	9de288c338cee67be0e9b836c87799bbc1db1c38
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 CCNB2 CCNB1	4.85e-04	176	39	3	581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNBD1 ARHGAP36 SCN9A	4.85e-04	176	39	3	d09e28606e2a6ed1f660898316765ca215085c18
ToppCell	NS-critical-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CACNA1C ZNF487 SLC7A2	4.85e-04	176	39	3	b794275fdd757b8fa2108e3c867f23da2649146d
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK10 SLC7A2 CIDEC	4.85e-04	176	39	3	b0b87eebcf5c994386b39ca607e17f10e9d9de74
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 CCNB2 CCNB1	4.93e-04	177	39	3	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK10 SLC7A2 CIDEC	4.93e-04	177	39	3	67cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 CCNB2 CCNB1	4.93e-04	177	39	3	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 SLC7A2 ARHGAP36	4.93e-04	177	39	3	1cb78133ac09ea3a3f5b5de07151033998406512
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TNXB CCNB2 CCNB1	5.01e-04	178	39	3	c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 CCNB2 CCNB1	5.01e-04	178	39	3	c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 SLC7A2 ARHGAP36	5.09e-04	179	39	3	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C SLC7A2 ARHGEF7	5.09e-04	179	39	3	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 SLC7A2 SCN9A	5.09e-04	179	39	3	3b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 CCNB2 CCNB1	5.18e-04	180	39	3	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C SLC7A2 TNXB	5.18e-04	180	39	3	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C SLC7A2 TNXB	5.18e-04	180	39	3	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 SLC7A2 SCN9A	5.26e-04	181	39	3	153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCell	P15-Endothelial-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KNTC1 CCNB2 CCNB1	5.26e-04	181	39	3	0c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 SLC7A2 ARHGAP36	5.26e-04	181	39	3	2f3d04d22d4ac016e61709ea5af3d48885c946c4
ToppCell	Healthy_Control-Lymphoid-T-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	KNTC1 CCNB2 CCNB1	5.26e-04	181	39	3	ac1ee313910c05b1b3cb497bae14565464919c21
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 CCNB2 CCNB1	5.26e-04	181	39	3	74311aac2fe27dc02a9be3bc20e0c7ef1c239049
ToppCell	P15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KNTC1 CCNB2 CCNB1	5.26e-04	181	39	3	f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 CCNB2 CCNB1	5.26e-04	181	39	3	cf13bf7a531a2d40f8d778629cf2431b684f65f3
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating-Lymphatic_EC_proliferating_L.2.5.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TNXB CCNB2 CCNB1	5.35e-04	182	39	3	f703963b5d1e8c1f95d78807521048553b0792d8
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 SLC7A2 ARHGAP36	5.35e-04	182	39	3	7dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC7A2 CCNB2 CIDEC	5.35e-04	182	39	3	21dcab170ffeef89faa9fee5008568cb6e15c694
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK10 SLC7A2 CIDEC	5.35e-04	182	39	3	94d061b7b5ebbfc564c644bc8b2d52341927145d
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac\|lymph-node_spleen / Manually curated celltypes from each tissue	HNMT CCNB2 CCNB1	5.35e-04	182	39	3	84018a84e1aa52fa52ccfc26db9cd1fb6d535b31
ToppCell	severe-multiplets\|World / disease stage, cell group and cell class	CCNB2 CWF19L1 CCNB1	5.35e-04	182	39	3	5e30ec7120a988d9ee3000513e1209618f28f5f9
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 CCNB2 CCNB1	5.35e-04	182	39	3	b1e66ccd5f33b4801f1cafddf97f5fc0c6dba8d1
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TNXB CCNB2 CCNB1	5.35e-04	182	39	3	ebd177ad5eac51bf2db0657596618bdf1e5d46e1
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	CACNA1C SLC7A2 ARHGEF7	5.43e-04	183	39	3	818fd886e0188091310825f9145fa53328f2c979
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 SLC7A2 ARHGAP36	5.43e-04	183	39	3	6e6128c5be5e0a2db6d84eecbf4dddd02d0216f8
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCNB2 CCNB1 SCN9A	5.43e-04	183	39	3	29b62dd542bc3f8df843998f577724f3818d4271
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 SLC7A2 ARHGAP36	5.43e-04	183	39	3	e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
Computational	Genes upregulated in subsets of cells of a given type within various tumors	DOCK10 KDM5B ARHGEF7	2.28e-04	50	26	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_29_NPC_OPC
Drug	1,1,1-trichloroethane	EIF3C ATM ATR AP1B1 AP2B1	6.76e-06	156	39	5	CID000006278
Drug	Flavanones	ATM ATR CCNB1	9.17e-06	24	39	3	ctd:D044950
Drug	1fl3	CCNB2 CCNB1	1.71e-05	4	39	2	CID000445650
Drug	Neostigmine bromide [114-80-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A	DOCK10 AP2B1 HNMT ARHGEF7 CWF19L1	1.99e-05	195	39	5	3294_UP
Drug	Chlorpyrifos	CACNA1C KDM5B ATM HUWE1 ING3 AP1B1 AP2B1 CCNB2 CCNB1	2.74e-05	960	39	9	ctd:D004390
Drug	aminopyrazine	HNMT TNXB	2.85e-05	5	39	2	CID000078747
Drug	Pyrazolopyridazine 1a	CCNB2 CCNB1	2.85e-05	5	39	2	CID006263849
Drug	alsterpaullone	ATM CCNB2 CCNB1	2.93e-05	35	39	3	CID005005498
Drug	4,4'-thiodipyridine	HNMT TNXB	4.27e-05	6	39	2	CID000604650
Drug	KU55933	ATM AP1B1 AP2B1	7.62e-05	48	39	3	CID005278396
Drug	3-(N-morpholino)propanesulfonic acid	AP1B1 TNXB CCNB2	7.62e-05	48	39	3	CID000070807
Drug	Mirex	SLC7A2 CCNB2 CCNB1	7.62e-05	48	39	3	ctd:D008917
Drug	hellebrigenin	ATM CCNB1	7.95e-05	8	39	2	ctd:C001330
Disease	ataxia telangiectasia (implicated_via_orthology)	ATM ATR	1.70e-06	2	39	2	DOID:12704 (implicated_via_orthology)
Disease	Benign neoplasm of stomach	ATM ATR	2.29e-04	17	39	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	ATM ATR	2.29e-04	17	39	2	C0496905
Disease	Carcinoma in situ of stomach	ATM ATR	2.29e-04	17	39	2	C0154060
Disease	Stomach Carcinoma	ATM ATR	3.52e-04	21	39	2	C0699791
Disease	Immunologic Deficiency Syndromes	CACNA1C ATM	4.23e-04	23	39	2	C0021051
Disease	melanoma	ATM MYH7B OR2AJ1	6.21e-04	126	39	3	EFO_0000756
Disease	breast cancer (is_implicated_in)	KDM5B ATM CCNB1	1.03e-03	150	39	3	DOID:1612 (is_implicated_in)
Disease	myositis	SLC6A15 AP1B1	1.22e-03	39	39	2	EFO_0000783
Disease	Inherited neuropathies	ATM SCN9A	1.29e-03	40	39	2	C0598589
Disease	nasopharynx carcinoma (is_marker_for)	ATM ATR	1.49e-03	43	39	2	DOID:9261 (is_marker_for)
Disease	optic disc area measurement	SLC6A15 CNBD1	1.63e-03	45	39	2	EFO_0006937
Disease	Squamous cell carcinoma of the head and neck	ING3 CCNB1	2.16e-03	52	39	2	C1168401
Disease	platelet component distribution width	DOCK10 CACNA1C AP2B1 RAB1A TNXB	3.03e-03	755	39	5	EFO_0007984

Protein segments in the cluster

Peptide	Gene	Start	Entry
LYLMNYAKSQPDMAI	AP2B1	71	P63010
EQELPFYFLQKLLMM	GVINP1	896	Q7Z2Y8
YRQLLLFYSKNPAMM	ADAD1	286	Q96M93
LNLMPQMKTLYLTYC	ARHGEF7	351	Q14155
LYLMNYAKSQPDMAI	AP1B1	71	Q10567
MEYPAIMLKELNSYS	CCDC180	611	Q9P1Z9
VSAALTLMMPYYLLD	SLC7A2	306	P52569
MSSMNPEYDYLFKLL	RAB1A	1	P62820
MKDSLLPDDLYMSFL	ARHGAP36	301	Q6ZRI8
QKNMLDGYRPSMLYI	TENT4B	346	Q8NDF8
MAMLYPELYKDLTKG	ATP9B	991	O43861
KYLYAFSIVPMKLMD	CWF19L1	236	Q69YN2
RNLMVYMYLPEAKES	CPSF1	1276	Q10570
MIQMLYYVKDIPATL	HNMT	141	P50135
MLYLEDYLEMIEQLP	ING3	1	Q9NXR8
ELQDMLLLSMNPYDY	MYH7B	341	A7E2Y1
KNLMVYSLPTMEILY	KNTC1	331	P50748
YTLDDLYPMMNALKL	KDM5B	736	Q9UGL1
LYPMMNALKLRAESY	KDM5B	741	Q9UGL1
MLFDERKYPYHLMLQ	HUWE1	1141	Q7Z6Z7
PVDLYYLMDLSYSMK	ITGB7	151	P26010
GVMEYYLMDAASLLP	NSUN4	151	Q96CB9
YLVSAMLLEIPYMAA	EIF3C	686	Q99613
EIYKMTTDPMLAYLQ	ATM	1751	Q13315
YLLGPLYAALKMESM	ATR	391	Q13535
TLAKYLMELTMLDYD	CCNB1	321	P14635
MLLKMYSLGLQAYFV	CACNA1C	571	Q13936
IASLYMPLYGMLLDN	DOCK10	1201	Q96BY6
MLLDNMPRIYLKDLY	DOCK10	1211	Q96BY6
LAKYLMELTLIDYDM	CCNB2	286	O95067
NPIYQMLELKLAMYI	FPGT	151	O14772
MLELKLAMYIDFPLN	FPGT	156	O14772
RYPILMKEYASALMA	OR2AJ1	131	Q8NGZ0
YMWKYISPLMLLSLL	SLC6A15	571	Q9H2J7
FDIMKYLFMLLSDLP	TDRD15	1756	B5MCY1
MVLKLIAMDPYEYFQ	SCN9A	791	Q15858
MEYAMKSLSLLYPKS	CIDEC	1	Q96AQ7
LAEMYLPSYDSMLSK	CNBD1	246	Q8NA66
VLYLSKYVLNMMALL	TCP11	156	Q8WWU5
NLEPERKYKMNMYGL	TNXB	1531	P22105
LEMYGEMLAVSKLYP	GPLD1	216	P80108
PYRDMMLENYSLLLS	ZNF487	61	B1APH4