Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein serine kinase activity

CDC42BPG TRIO KALRN MKNK2 OBSCN LMTK3 MAP3K3 MAP3K4 SBK1 CIITA NRK MAP3K9 PNCK CDK3

1.75e-0636316314GO:0106310
GeneOntologyMolecularFunctionacetylcholine receptor regulator activity

SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

2.38e-06271635GO:0030548
GeneOntologyMolecularFunctionneurotransmitter receptor regulator activity

SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

2.88e-06281635GO:0099602
GeneOntologyMolecularFunctionprotein kinase activity

CDC42BPG HK1 TRIO KALRN MKNK2 OBSCN LMTK3 MAP3K3 MAP3K4 SBK1 CIITA COQ8A EPHA2 NRK MAP3K9 PNCK CDK3

8.71e-0660016317GO:0004672
GeneOntologyMolecularFunctionprotein kinase binding

SOX9 ANK2 DSCAM FRS2 CASQ2 SPDYE18 ADCY6 AXIN1 MAVS NFATC1 CSPG4 SPDYE2 SPDYE21 SPDYE5 SCRIB SPDYE2B CDH2 TOP2A RFPL3 SPDYE6 SPDYE16

9.12e-0687316321GO:0019901
GeneOntologyMolecularFunctionkinase binding

SOX9 ANK2 WWC3 DSCAM FRS2 CASQ2 SPDYE18 ADCY6 AXIN1 MAVS NFATC1 CSPG4 SPDYE2 SPDYE21 SPDYE5 SCRIB SPDYE2B CDH2 TOP2A RFPL3 SPDYE6 SPDYE16

1.35e-0596916322GO:0019900
GeneOntologyMolecularFunctionN-acetylglucosamine 6-O-sulfotransferase activity

CHST5 CHST4 CHST7

1.82e-0571633GO:0001517
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

CDC42BPG TRIO KALRN MKNK2 OBSCN LMTK3 MAP3K3 MAP3K4 SBK1 CIITA NRK MAP3K9 PNCK CDK3

1.84e-0544616314GO:0004674
GeneOntologyMolecularFunctionkinase activity

CDC42BPG HK1 TRIO KALRN MKNK2 OBSCN LMTK3 TRRAP MAP3K3 MAP3K4 SBK1 CIITA COQ8A EPHA2 NRK MAP3K9 PNCK CDK3

5.45e-0576416318GO:0016301
GeneOntologyMolecularFunctionvery long-chain fatty acyl-CoA hydrolase activity

BAAT ABCD1

6.62e-0521632GO:0052817
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

CDC42BPG HK1 TRIO KALRN MKNK2 OBSCN LMTK3 MAP3K3 MAP3K4 SBK1 CIITA COQ8A EPHA2 NRK MAP3K9 PNCK CDK3

7.17e-0570916317GO:0016773
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

CDC42BPG HK1 TRIO KALRN MKNK2 OBSCN LMTK3 PARP14 TRRAP MAP3K3 MAP3K4 SBK1 CIITA COQ8A EPHA2 NRK GYS2 MAP3K9 PNCK CDK3

8.24e-0593816320GO:0016772
GeneOntologyMolecularFunctionD-glucose binding

HK1 GYS2 PYGL

1.82e-04141633GO:0005536
GeneOntologyMolecularFunctionDNA/RNA helicase activity

DHX9 PIF1

3.93e-0441632GO:0033677
GeneOntologyMolecularFunctioncadherin binding

MRE11 OBSCN MPRIP ESYT2 EPHA2 SCRIB CDH2 CDH11 MPP7 RPL15

4.85e-0433916310GO:0045296
GeneOntologyMolecularFunctionTORC2 complex binding

ARMH4 NCKAP1L

6.52e-0451632GO:1904841
GeneOntologyMolecularFunctionsignaling adaptor activity

WWC3 FRS2 AXIN1 MAVS SCRIB MPP7

6.71e-041291636GO:0035591
GeneOntologyMolecularFunctioncytoskeletal anchor activity

ANK2 OBSL1 BIN3

9.53e-04241633GO:0008093
GeneOntologyMolecularFunctionMAP kinase kinase kinase activity

MAP3K3 MAP3K4 MAP3K9

1.35e-03271633GO:0004709
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein serine/threonine kinase activity

SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

1.20e-06251595GO:0045737
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein kinase activity

SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

2.18e-06281595GO:1904031
GeneOntologyBiologicalProcessmuscle cell differentiation

DOCK1 SOX9 ANK2 CNTNAP1 OBSCN FRS2 OBSL1 CASQ2 BIN3 IGF2 ADRB1 NFATC1 NFATC4 ANHX CDH2

1.61e-0553115915GO:0042692
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

DOCK1 SOX9 ANK2 DSCAM CNTNAP1 OBSCN FRS2 OBSL1 SOX18 RNF213 CASQ2 ST14 MAP3K3 AXIN1 FMNL3 SOX7 IGF2 RPL7L1 NFATC1 NFATC4 EPHA2 CSPG4 KLHL12 SCRIB HERC1 IHH CDH11

2.47e-05148315927GO:0048646
GeneOntologyBiologicalProcessmale germ-line sex determination

SOX9 MAP3K4

5.91e-0521592GO:0019100
GeneOntologyBiologicalProcessprotein localization to M-band

ANK2 OBSCN

5.91e-0521592GO:0036309
GeneOntologyBiologicalProcessprimary sex determination, germ-line

SOX9 MAP3K4

5.91e-0521592GO:0007542
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

SOX9 MRE11 DSCAM PARP14 MAP3K4 AXIN1 MPRIP MAVS CD86 EPHA2 CSPG4 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16 NCKAP1L

1.13e-0478015917GO:0042327
GeneOntologyBiologicalProcessmuscle structure development

DOCK1 SOX9 SOX15 FLOT2 ANK2 CNTNAP1 OBSCN FRS2 OBSL1 CASQ2 BIN3 IGF2 ADRB1 NFATC1 NFATC4 ANHX ARID2 CDH2

1.14e-0485815918GO:0061061
GeneOntologyBiologicalProcessaxial mesoderm formation

AXIN1 EPHA2

1.76e-0431592GO:0048320
GeneOntologyBiologicalProcessprimary sex determination

SOX9 MAP3K4

1.76e-0431592GO:0007538
GeneOntologyBiologicalProcessgerm-line sex determination

SOX9 MAP3K4

1.76e-0431592GO:0018992
GeneOntologyBiologicalProcessmuscle cell development

ANK2 CNTNAP1 OBSCN OBSL1 CASQ2 BIN3 ADRB1 NFATC4 ANHX

1.87e-042591599GO:0055001
GeneOntologyCellularComponentcell-cell contact zone

FLOT2 ANK2 OBSCN OBSL1 SCRIB CDH2

8.55e-05941606GO:0044291
DomainSpy1

SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16

1.73e-10111626PF11357
DomainSpeedy

SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16

1.73e-10111626IPR020984
DomainCarbohydrate_sulfotransferase

CHST5 CHST4 CHST7

2.19e-0571623IPR016469
DomainPROTEIN_KINASE_DOM

CDC42BPG TRIO KALRN MKNK2 OBSCN LMTK3 MAP3K3 MAP3K4 SBK1 COQ8A EPHA2 NRK MAP3K9 PNCK CDK3

2.65e-0549316215PS50011
DomainPROTEIN_KINASE_ATP

CDC42BPG TRIO KALRN MKNK2 OBSCN LMTK3 MAP3K3 MAP3K4 SBK1 EPHA2 NRK MAP3K9 PNCK CDK3

4.84e-0545916214PS00107
DomainSer/Thr_kinase_AS

CDC42BPG TRIO KALRN MKNK2 OBSCN MAP3K3 MAP3K4 SBK1 NRK MAP3K9 PNCK CDK3

6.82e-0535716212IPR008271
DomainS_TKc

CDC42BPG TRIO KALRN MKNK2 OBSCN MAP3K3 MAP3K4 SBK1 NRK MAP3K9 PNCK CDK3

7.19e-0535916212SM00220
DomainK_chnl_inward-rec_Kir2.2

KCNJ12 KCNJ18

7.48e-0521622IPR003272
DomainEIF3C_N_dom

EIF3CL EIF3C

7.48e-0521622IPR008905
DomaineIF-3c_N

EIF3CL EIF3C

7.48e-0521622PF05470
DomainEIF3C

EIF3CL EIF3C

7.48e-0521622IPR027516
DomainKinase-like_dom

CDC42BPG TRIO KALRN MKNK2 OBSCN TRRAP MAP3K3 MAP3K4 SBK1 COQ8A EPHA2 NRK MAP3K9 PNCK CDK3

7.77e-0554216215IPR011009
DomainPROTEIN_KINASE_ST

CDC42BPG TRIO KALRN MKNK2 OBSCN MAP3K3 MAP3K4 SBK1 NRK MAP3K9 PNCK CDK3

7.79e-0536216212PS00108
DomainPkinase

CDC42BPG TRIO KALRN MKNK2 OBSCN MAP3K3 MAP3K4 SBK1 NRK MAP3K9 PNCK CDK3

1.26e-0438116212PF00069
DomainK_chnl_inward-rec_Kir_N

KCNJ12 KCNJ18

2.23e-0431622IPR013673
DomainSox_C

SOX18 SOX7

2.23e-0431622IPR021934
DomainSox7/17/18_central

SOX18 SOX7

2.23e-0431622IPR033392
DomainIRK_N

KCNJ12 KCNJ18

2.23e-0431622PF08466
DomainSox17_18_mid

SOX18 SOX7

2.23e-0431622PF12067
DomainSOX_C

SOX18 SOX7

2.23e-0431622PS51516
DomainProt_kinase_dom

CDC42BPG TRIO KALRN MKNK2 OBSCN MAP3K3 MAP3K4 SBK1 EPHA2 NRK MAP3K9 PNCK CDK3

3.47e-0448916213IPR000719
DomainP-loop_NTPase

MAGI1 CHST5 MRAS GBP1 RNF213 ATAD2 DHX9 CTPS2 CIITA STARD9 CHST4 HELZ2 ABCD1 CHST7 DNAH9 SNRNP200 PIF1 MPP7

4.16e-0484816218IPR027417
DomainNFAT

NFATC1 NFATC4

7.35e-0451622IPR008366
Pubmed

Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.

SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

2.81e-109165536272447
Pubmed

Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

2.82e-0913165515611625
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

MRE11 WDR36 PEG10 PRPF6 CCDC12 ATAD2 TRRAP TFCP2 DMAP1 MPRIP DHX9 RPL7L1 ARID2 PDCD11 LSM14A EIF3C SNRNP200 TOP2A RPL15 DCTN3

4.34e-098471652035850772
Pubmed

Characterization of a new family of cyclin-dependent kinase activators.

SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

1.34e-0817165515574121
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

FLOT2 DMXL2 KIFBP HK1 WDR36 ANK2 PEG10 FRS2 OBSL1 PRPF6 ME2 NDUFB10 TFCP2 CDKAL1 MPRIP DHX9 SPCS3 ESYT2 RPL7L1 EPHA2 PDCD11 SCRIB SNRNP200 MPP7 RPL15

4.00e-0814871652533957083
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

MRE11 KIFBP HK1 PSMD5 PRPF6 TRRAP MAP3K4 DHX9 SPCS3 CTPS2 PDCD11 PDS5A EIF3C SCRIB ATP2A3 SNRNP200 TOP2A

4.91e-087041651729955894
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

MAGI1 FLOT2 ANK2 FRS2 PARP14 ATAD2 ADCY6 ST14 ESYT2 EPHA2 NRK CSPG4 SCRIB MPP7 IQCG

1.02e-075691651530639242
Pubmed

DSCAM regulates delamination of neurons in the developing midbrain.

SOX9 MAGI1 DSCAM CDH2

1.57e-0711165432917586
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

CCNL2 TRIO MTHFD2 OBSL1 PSMD5 TRRAP MAP3K3 MAP3K4 AXIN1 EIF3CL MPRIP IGF2 NFATC4 EPHA2 NRK MAP3K9 EIF3C CDK3

3.74e-079101651836736316
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CCNL2 MRE11 FLOT2 MTHFD2 NTAQ1 OBSL1 RNF213 SOWAHC TRRAP ADCY6 CDKAL1 DMAP1 SULF2 COQ8A ARID2 SCRIB PCCA AGBL1 IQCM TOP2A

3.84e-0711161652031753913
Pubmed

Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth.

SOX9 SOX15 SOX18 SOX7

4.71e-071416548921394
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

FLOT2 HK1 TFCP2 AXIN1 DHX9 PDCD11 PYGL EIF3C SCRIB PCCA CDH2 TOP2A RPL15

6.10e-074841651331995728
Pubmed

Dominant-negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types.

SOX9 SOX18 SOX7 NFATC1

6.40e-0715165428512199
Pubmed

GlcNAc6ST3 is a keratan sulfate sulfotransferase for the protein-tyrosine phosphatase PTPRZ in the adult brain.

CHST5 CHST4 CHST7

1.04e-065165330867513
Pubmed

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.

CDC42BPG PEG10 OBSL1 DHX9 MAVS COQ8A PYGL PDS5A SNRNP200 CDK3

1.12e-062831651021903422
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

MRE11 PSMD5 PRPF6 TRRAP DHX9 ARID2 PDS5A SNRNP200 RAVER1

1.17e-06220165935785414
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DOCK1 MAGI1 MRE11 FLOT2 ANK2 FRS2 CDKAL1 DHX9 ESYT2 EPHA2 PDS5A SCRIB SNRNP200 MPP7 RPL15

1.60e-067081651539231216
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

MRE11 FLOT2 WDR36 PRPF6 NDUFB10 EIF3CL MPRIP DHX9 RPL7L1 KLHL7 SERPINB3 HELZ2 PDCD11 LSM14A SCRIB SNRNP200 TOP2A CBX8 RPL15 RAVER1

2.39e-0612571652036526897
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

MRE11 FLOT2 WDR36 ANK2 PARG ME2 TFCP2 MPRIP MAVS ARID2 LSM14A EIF3C SCRIB PCCA SNRNP200 TOP2A RPL15

2.47e-069341651733916271
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

FLOT2 KIFBP HK1 WDR36 MTHFD2 OBSL1 RNF213 LARP4 ME2 NDUFB10 TFCP2 CDKAL1 DHX9 SPCS3 ESYT2 RPL7L1 MAVS ARID2 PDCD11 HERC1 TOP2A RAVER1

2.59e-0614961652232877691
Pubmed

Expression of Sox transcription factors in the developing mouse pancreas.

SOX9 SOX15 SOX18 SOX7

2.74e-0621165412815626
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MRE11 HK1 WDR36 PRPF6 LARP4 ATAD2 TRRAP ME2 HELZ2 PDCD11 PYGL PDS5A SNRNP200 RPL15

3.15e-066531651422586326
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

MRE11 KIFBP PARG OBSL1 TRRAP TFCP2 DMAP1 ESYT2 NFATC1 NFATC4 SERPINB3 PDS5A SCRIB SNRNP200 TOP2A GAA

3.60e-068571651625609649
Pubmed

Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family.

CHST5 CHST4 CHST7

3.62e-067165311181564
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

MRE11 WDR36 PRPF6 CCDC12 TRRAP NDUFB10 TFCP2 CDKAL1 DMAP1 DHX9 ESYT2 RPL7L1 PDCD11 PDS5A PCCA SNRNP200 TOP2A CBX8 RPL15 RAVER1

3.69e-0612941652030804502
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

FLOT2 DMXL2 HK1 KALRN PRPF6 LMTK3 TRRAP DMAP1 DHX9 SPCS3 SULF2 ARID2 HELZ2 PDS5A EIF3C SNRNP200 CBX8 RPL15

4.31e-0610821651838697112
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MRE11 FLOT2 KIFBP HK1 WDR36 TRIO PRPF6 ATAD2 ME2 TFCP2 EIF3CL DHX9 RPL7L1 SERPINB3 STARD9 PDCD11 PDS5A EIF3C SNRNP200 TOP2A RPL15

4.33e-0614251652130948266
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

MRE11 PRPF6 PARP14 MPRIP DHX9 PDS5A SNRNP200 TOP2A RPL15 RAVER1

5.72e-063401651024332808
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

RIN3 TRIO KALRN SZT2 OBSCN FRMD8 TRRAP ST14 MPRIP MROH1 NFATC1 CSPG4 HELZ2 PDCD11 ABCD1 HERC1 ATP2A3 RASAL1

5.74e-0611051651835748872
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

FLOT2 TRIO FRS2 CDKAL1 MPRIP ESYT2 CTPS2 EPHA2 SCRIB CDH2 MPP7

5.96e-064211651136976175
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 MAGI1 CDC42BPG TRIO OBSCN RNF213 CCDC12 LARP4 TRRAP ME2 SBK1 ESYT2 IGF2 NFATC1 COQ8A LSM14A PCCA ALG12 SLC2A11 DOP1A RAVER1

8.45e-0614891652128611215
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

WDR36 PRPF6 LARP4 TRRAP MAP3K4 DMAP1 MPRIP DHX9 ARID2 SCRIB TOP2A

9.02e-064401651134244565
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KIFBP WWC3 PARP14 ESYT2 SULF2 MAVS

1.02e-05103165610574462
Pubmed

Sulfation of the human immunodeficiency virus envelope glycoprotein.

CHST5 CHST4 CHST7

1.23e-051016531433500
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

FLOT2 WDR36 MTHFD2 OBSL1 PRPF6 LARP4 EIF3CL MPRIP DHX9 RPL7L1 PDCD11 EIF3C SCRIB SNRNP200 TOP2A RPL15

1.28e-059491651636574265
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DMXL2 OBSL1 ADCY6 ESYT2 SULF2 HELZ2 SCRIB SNRNP200

1.30e-05225165812168954
Pubmed

Human transcription factor protein interaction networks.

SOX9 MRE11 SOX15 FLOT2 PEG10 LARP4 TRRAP TFCP2 DMAP1 MPRIP RPL7L1 NFATC4 ARID2 PDCD11 PDS5A LSM14A EIF3C HERC1 PCCA RAVER1

1.57e-0514291652035140242
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

HK1 KALRN OBSCN RNF213 PSMD5 PRPF6 COQ8A CDH2 SNRNP200

1.61e-05304165932235678
Pubmed

Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation.

SOX18 CSPG4 CDH2

1.68e-0511165319429912
Pubmed

Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine.

CHST5 CHST4 CHST7

1.68e-051116538419650
Pubmed

Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency.

SOX9 IHH TOP2A

1.68e-0511165328323137
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

FLOT2 KIFBP HK1 WDR36 MTHFD2 PSMB9 RNF213 PRPF6 NDUFB10 CDKAL1 ESYT2 RPL7L1 COQ8A PDCD11 PDS5A EIF3C SCRIB SNRNP200 TOP2A RAVER1

1.76e-0514401652030833792
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

FLOT2 WDR36 FMNL3 ESYT2 EPHA2 KLHL12 SCRIB SNRNP200 SLC2A11

2.03e-05313165938270169
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

MRE11 PRPF6 TRRAP DMAP1 DHX9 ARID2 PDCD11 PDS5A TOP2A CBX8

2.05e-053941651027248496
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MRE11 PARG ATAD2 TRRAP ADCY6 EIF3CL DHX9 ESYT2 HELZ2 EIF3C SCRIB SNRNP200 TOP2A RAVER1

2.13e-057741651415302935
Pubmed

FLOT2 upregulation promotes growth and invasion by interacting and stabilizing EphA2 in gliomas.

FLOT2 EPHA2

2.24e-052165233631676
Pubmed

Phosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer.

NFATC4 CDK3

2.24e-052165227893713
Pubmed

Essential role of obscurin kinase-1 in cardiomyocyte coupling via N-cadherin phosphorylation.

OBSCN CDH2

2.24e-052165238127465
Pubmed

Inhibition of miR-101-3p prevents human aortic valve interstitial cell calcification through regulation of CDH11/SOX9 expression.

SOX9 CDH11

2.24e-052165236809926
Pubmed

CDH2 and CDH11 act as regulators of stem cell fate decisions.

CDH2 CDH11

2.24e-052165225771201
Pubmed

EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.

EIF3CL EIF3C

2.24e-052165236157221
Pubmed

Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS.

MRAS SCRIB

2.24e-052165237277529
Pubmed

CREG inhibits migration of human vascular smooth muscle cells by mediating IGF-II endocytosis.

CREG1 IGF2

2.24e-052165219769965
Pubmed

Role of Kir2.2 in hypercapnic ventilatory response during postnatal development of mouse.

KCNJ12 KCNJ18

2.24e-052165215705530
Pubmed

Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes.

CDH2 CDH11

2.24e-052165218383368
Pubmed

Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.

TRIO KALRN

2.24e-052165226858404
Pubmed

SOX15 and SOX7 differentially regulate the myogenic program in P19 cells.

SOX15 SOX7

2.24e-052165219489079
Pubmed

Ankyrin-B is required for intracellular sorting of structurally diverse Ca2+ homeostasis proteins.

ANK2 ATP2A3

2.24e-052165210579720
Pubmed

Mutations in CNTNAP1 and ADCY6 are responsible for severe arthrogryposis multiplex congenita with axoglial defects.

CNTNAP1 ADCY6

2.24e-052165224319099
Pubmed

Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos.

CDH2 CDH11

2.24e-05216527750650
Pubmed

N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms.

CDH2 CDH11

2.24e-052165220605916
Pubmed

Cell-cell interaction mediated by cadherin-11 directly regulates the differentiation of mesenchymal cells into the cells of the osteo-lineage and the chondro-lineage.

CDH2 CDH11

2.24e-052165215476585
Pubmed

Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma.

CHST5 CHST4

2.24e-052165212107080
Pubmed

Chondroitin sulfate-E fine-tunes osteoblast differentiation via ERK1/2, Smad3 and Smad1/5/8 signaling by binding to N-cadherin and cadherin-11.

CDH2 CDH11

2.24e-052165222440395
Pubmed

The Role of SOX9 in IGF-II-Mediated Pulmonary Fibrosis.

SOX9 IGF2

2.24e-052165237510994
Pubmed

RNA helicase A interacts with dsDNA and topoisomerase IIalpha.

DHX9 TOP2A

2.24e-052165212711669
Pubmed

Distinct roles of NFATc1 and NFATc4 in human primary myoblast differentiation and in the maintenance of reserve cells.

NFATC1 NFATC4

2.24e-052165228760926
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

PRPF6 TFCP2 DHX9 NFATC1 NFATC4 SERPINB3 PDCD11 PDS5A LSM14A EIF3C SCRIB SNRNP200

2.43e-055831651229844126
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MRE11 HK1 WDR36 PSMD5 PRPF6 LARP4 ATAD2 TRRAP MPRIP DHX9 RPL7L1 SERPINB3 PDCD11 PYGL PDS5A SCRIB SNRNP200 TOP2A RPL15

2.49e-0513531651929467282
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

MRE11 WDR36 PARP14 TRRAP DMAP1 FMNL3 EIF3C SCRIB SNRNP200 RPL15

2.87e-054101651026949251
Pubmed

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements.

SOX9 SOX15 SOX18

2.90e-0513165322344693
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

MRE11 WDR36 ANK2 PEG10 OBSL1 PRPF6 LARP4 TFCP2 MPRIP SPCS3 COQ8A STARD9 EPHA2 HELZ2 PDCD11 LSM14A KLHL12 CBX8 RPL15

2.98e-0513711651936244648
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

DOCK1 KALRN SOWAHC DMAP1 EIF3CL MAVS EIF3C SCRIB TOP2A CDK3 RAVER1

3.09e-055031651116964243
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

MRE11 FLOT2 HK1 OBSCN PSMD5 MPRIP DHX9 EIF3C SNRNP200

3.36e-05334165930425250
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

WDR36 RNF213 PRPF6 PARP14 ZNF496 PCCA TOP2A RPL15

3.86e-05262165836880596
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SOX9 DMXL2 ANK2 DSCAM TRIO KALRN PEG10 CNTNAP1 OBSL1 NAP1L3 PSMD5 DMAP1 MPRIP KLHL7 EIF3C SCRIB SNRNP200 RPL15

4.25e-0512851651835914814
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

RNF213 TRRAP DMAP1 DHX9 PDS5A SNRNP200 TOP2A

4.30e-05195165719454010
Pubmed

Trio controls the mature organization of neuronal clusters in the hindbrain.

TRIO CDH2 CDH11

4.58e-0515165317898204
Pubmed

Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina.

SOX18 SOX7 CSPG4

4.58e-0515165326630461
Pubmed

MAP3Ks as central regulators of cell fate during development.

MAP3K3 MAP3K4 MAP3K9

4.58e-0515165318855897
Pubmed

Differential isoform expression and alternative splicing in sex determination in mice.

SOX9 SOX15 SOX7

4.58e-0515165330871468
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

MRE11 WDR36 ANK2 EIF3CL ESYT2 EIF3C TOP2A RPL15

4.90e-05271165832433965
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DOCK1 TRIO CNTNAP1 PARP14 MPRIP DHX9 SNRNP200

5.38e-05202165733005030
Pubmed

A protein interaction landscape of breast cancer.

FLOT2 HK1 TRIO MTHFD2 MPRIP DHX9 ARID2 PDCD11 PDS5A TOP2A CBX8 RPL15

5.46e-056341651234591612
Pubmed

Beta-catenin interacts with the FUS proto-oncogene product and regulates pre-mRNA splicing.

PRPF6 DHX9 TOP2A

5.61e-0516165316230076
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MAGI1 DMXL2 KIFBP ANK2 DSCAM TRIO KALRN CNTNAP1 LMTK3 MPRIP KLHL7 SCRIB CDH2 CDH11 RASAL1

5.94e-059631651528671696
Pubmed

Distinct substrate specificities of human GlcNAc-6-sulfotransferases revealed by mass spectrometry-based sulfoglycomic analysis.

CHST5 CHST4

6.69e-053165230093410
Pubmed

Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfate.

CHST5 CHST4

6.69e-053165212218059
Pubmed

Evolution of the Cdk-activator Speedy/RINGO in vertebrates.

SPDYE2 SPDYE6

6.69e-053165222763696
Pubmed

NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas.

SOX9 NFATC1

6.69e-053165225623042
Pubmed

Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.

TRIO KALRN

6.69e-053165231801062
Pubmed

A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.

SOX18 SOX7

6.69e-053165234570228
Pubmed

Polo-like kinase 1 activated by the hepatitis B virus X protein attenuates both the DNA damage checkpoint and DNA repair resulting in partial polyploidy.

MRE11 TOP2A

6.69e-053165220624918
Pubmed

Stabilization of HPV16 E6 protein by PDZ proteins, and potential implications for genome maintenance.

MAGI1 SCRIB

6.69e-053165221489588
Pubmed

Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex.

OBSCN OBSL1

6.69e-053165220133654
Pubmed

Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K(+) current in K(+)-mediated vasodilation.

KCNJ12 KCNJ18

6.69e-053165210904001
Pubmed

Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line.

ANK2 OBSCN

6.69e-053165218782775
Pubmed

Perturbing cohesin dynamics drives MRE11 nuclease-dependent replication fork slowing.

MRE11 PDS5A

6.69e-053165229917110
Pubmed

Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.

OBSCN OBSL1

6.69e-053165227989621
Pubmed

Low-affinity spermine block mediating outward currents through Kir2.1 and Kir2.2 inward rectifier potassium channels.

KCNJ12 KCNJ18

6.69e-053165217640933
InteractionRPS6KA2 interactions

MAGI1 FLOT2 FRS2 EIF3CL RPL7L1 EPHA2 EIF3C SCRIB MPP7 DCTN3

3.87e-0619616010int:RPS6KA2
InteractionKCNA3 interactions

DOCK1 MAGI1 MRE11 FLOT2 ANK2 SZT2 FRS2 RNF213 CDKAL1 MPRIP DHX9 ESYT2 EPHA2 PYGL PDS5A SCRIB SNRNP200 MPP7 DOP1A RPL15

1.97e-0587116020int:KCNA3
InteractionLCK interactions

FLOT2 RIN3 TRIO KALRN MTHFD2 FRS2 OBSL1 CDKAL1 MPRIP EPHA2 SCRIB MPP7 RPL15 CDK3

2.04e-0546316014int:LCK
InteractionMEN1 interactions

MRE11 WDR36 PEG10 RNF213 PRPF6 CCDC12 PARP14 ATAD2 TRRAP TFCP2 DMAP1 DHX9 RPL7L1 ARID2 PDCD11 PDS5A EIF3C SNRNP200 TOP2A CBX8 RPL15 DCTN3

2.20e-05102916022int:MEN1
InteractionDOT1L interactions

WDR36 PEG10 PRPF6 CCDC12 ATAD2 TRRAP TFCP2 DMAP1 MPRIP DHX9 SOX7 RPL7L1 ARID2 PDCD11 LSM14A EIF3C SNRNP200 TOP2A RPL15

2.29e-0580716019int:DOT1L
InteractionPLAC1 interactions

OBSL1 TRRAP ST14 DMAP1

3.59e-05241604int:PLAC1
GeneFamilySpeedy/RINGO cell cycle regulator family

SPDYE2 SPDYE5 SPDYE2B SPDYE6

6.18e-07121104756
GeneFamilySRY-boxes

SOX9 SOX15 SOX18 SOX7

4.69e-06191104757
GeneFamilyNuclear factors of activated T-cells

NFATC1 NFATC4

3.62e-0451102665
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

MAP3K3 MAP3K4 MAP3K9

4.04e-04241103654
GeneFamilySulfotransferases, membrane bound

CHST5 CHST4 CHST7

1.46e-03371103763
GeneFamilyDynein regulatory complex

IQCD IQCG

1.95e-03111102981
GeneFamilyPDZ domain containing

MAGI1 LNX2 GRID2IP SCRIB MPP7

2.37e-0315211051220
GeneFamilyFibronectin type III domain containing

COL7A1 DSCAM KALRN OBSCN EPHA2

2.96e-031601105555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

DSCAM TRIO KALRN OBSCN OBSL1

3.04e-031611105593
GeneFamilyPotassium voltage-gated channel subfamily J

KCNJ12 KCNJ18

4.16e-03161102276
CoexpressionKIM_WT1_TARGETS_UP

SOX9 TRIO SOWAHC BIN3 IGF2 NFATC1 EPHA2 CSPG4 MAP3K9 CDH2 IQCG

1.16e-0721716211M9128
CoexpressionHARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_28DY_POSITIVE

DOCK1 SOX15 RIN3 TRIO MTHFD2 MKNK2 SOWAHC ST14 MAP3K3 SULF2 RPL7L1 MROH1 CIITA COQ8A CD86 EPHA2 EIF3C ABCD1 PCCA CBX8 MPP7 NCKAP1L

9.60e-06125016222M41099
CoexpressionGSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_UP

MAGI1 TRIO SZT2 CNTNAP1 FRS2 BIN3 MAP3K9 DLEC1

3.37e-051981628M4309
CoexpressionGSE14308_TH1_VS_NATURAL_TREG_DN

RIN3 C2orf76 CREG1 TFCP2 AXIN1 NFATC1 PNCK KLHL12

3.49e-051991628M3381
CoexpressionHALLMARK_INTERFERON_GAMMA_RESPONSE

MTHFD2 PSMB9 RNF213 PARP14 CIITA CD86 HELZ2 C1R

3.62e-052001628M5913
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSMB9 ATAD2 SPCS3 RPL7L1 CD86 MAP3K9 TOP2A NCKAP1L

2.78e-07174164809b091e24317c3f7bac043f04762a533e30793de
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

SOX9 COL7A1 TRIO PSMB9 GBP1 RNF213 PARP14 HELZ2

4.08e-0718316488f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST5 DSCAM TRIO SULF2 CSPG4 SORCS3 CHST7 ARMH4

5.01e-071881648a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST5 DSCAM TRIO SULF2 CSPG4 SORCS3 CHST7 ARMH4

5.01e-071881648c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellFetal_29-31_weeks-Immune-monocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DMXL2 RIN3 MAP3K3 SULF2 CIITA CD86 ADAP2 NCKAP1L

7.14e-0719716488b9a88fb671d5c2b25d291c851e2b8a478f2610c
ToppCellImmune-monocyte|World / Lineage, Cell type, age group and donor

DMXL2 RIN3 MAP3K3 SULF2 CIITA CD86 ADAP2 NCKAP1L

7.41e-071981648d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-mDC|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MTHFD2 SULF2 CIITA CD86 RASAL1 ADAP2 NCKAP1L

3.04e-0616816472dca1c4a33b6da9357fa3b2a523af19baab1c21c
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

DMXL2 OBSCN CASQ2 CD86 CDH2 ADAP2 NCKAP1L

3.28e-0617016474232fe937909f93d3736988c707b8f95ce993398
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MTHFD2 SULF2 CIITA CD86 RASAL1 ADAP2 NCKAP1L

3.28e-0617016473cbeea6bfa500928c413b1c6129f6dedc769cd1e
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDC42BPG MTHFD2 ADCY6 CDKAL1 AXIN1 DHX9 MPP7

4.13e-06176164724b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASQ2 ADCY6 NFATC4 GYS2 CSPG4 ATP2A3 ADAP2

4.45e-0617816477467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX18 MAP3K3 SOX7 SPDYE5 EXOC3L2 TOP2A PIF1

4.45e-061781647ea10117026021c959ffc871fc377cdb3e161d264
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

DMXL2 WDR36 RNF213 CDKAL1 MAP3K4 CIITA ARID2

5.93e-0618616478571956890fc9894d766ba294a28e376b4aba428
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CASQ2 NFATC4 EPHA2 CSPG4 ATP2A3 ADAP2

6.10e-061221646c16110934172f174f4aefe14b81abce8514b30f0
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell-Peri|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CASQ2 NFATC4 EPHA2 CSPG4 ATP2A3 ADAP2

6.10e-061221646006ac4f6807e688554d36557d29d5e5a0bc3c36f
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CASQ2 NFATC4 EPHA2 CSPG4 ATP2A3 ADAP2

6.10e-061221646f3d9a5893fdee3562880fb6fc132b88169a7d997
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 HK1 ANK2 ADCY6 ST14 ADRB1 FAM107A

6.36e-061881647ab6fa1beff91584d9303c2a33735de89aae8d5cd
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

SOX15 COL7A1 HK1 DUSP7 SOWAHC SOX7 PYGL

6.59e-061891647533c302df467d13ab639232daf4f8cafb808260b
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 B3GNT9 ANK2 OBSL1 CASQ2 SULF2 CDH2

6.82e-06190164796a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

DMXL2 RIN3 RNF213 CD86 TOP2A ADAP2 NCKAP1L

7.30e-061921647a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

DMXL2 RIN3 MAP3K3 SULF2 CIITA CD86 NCKAP1L

8.35e-061961647cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellmetastatic_Lymph_Node-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

RIN3 MTHFD2 PSMB9 GBP1 CCDC12 CD86 PIF1

8.35e-061961647e1a9198bc51e01308f066323c5e089cfaf04b2ca
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMXL2 RNF213 PARP14 CIITA CD86 ADAP2 NCKAP1L

8.63e-06197164710190b877bf46ba2163d203df9dd3b498c66e52f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN SOX18 FMNL3 SULF2 CIITA STARD9 EXOC3L2

8.63e-061971647cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN SOX18 FMNL3 SULF2 CIITA STARD9 EXOC3L2

8.63e-061971647412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellMild-CD8+_T_activated|Mild / Disease group and Cell class

PSMB9 GBP1 RNF213 PARP14 SBK1 HELZ2 DOP1A

8.92e-061981647ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCell(00)_Basal-(1)_GFP|(00)_Basal / shred by cell type by condition

SOX9 DUSP7 FRMD8 ST14 SOX7 SERPINB3 EPHA2

9.22e-061991647105b15157f35df3fdf857e306f11e4e8200e05d4
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PSMB9 GBP1 PARP14 SULF2 NFATC4 C1R CDH11

9.22e-061991647fcbb3a9c0f4c5b4c1f09db24b9f50cc1166fa43b
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMXL2 RNF213 PARP14 CIITA CD86 ADAP2 NCKAP1L

9.22e-0619916475ceeed92f831d068ff4bb3994f420002338330e7
ToppCell(02)_MMP9/10+|World / shred by cell type by condition

COL7A1 MTHFD2 DUSP7 SOWAHC SULF2 IGF2 CDH2

9.22e-0619916473f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

DMXL2 PSMB9 GBP1 RNF213 PARP14 CIITA NCKAP1L

9.22e-061991647155b03b859157013e9142e9248551369127d9204
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SULF2 CIITA ABCD1 CHST7 CDH2 RASAL1 NCKAP1L

9.22e-06199164782759af613ebfffe037afda55159bf6af812c3ac
ToppCellmild-CD163+_Monocytes_(Sample_ID1_d7)|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DMXL2 GBP1 PARP14 CREG1 CD86 HELZ2 ADAP2

9.53e-06200164782126e25bfd8fba78dc1348fa5ad6a576289a139
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP1 SOWAHC KCNJ12 SORCS3 ADAP2 NCKAP1L

1.19e-051371646587a369b148bb2600c06db39298feddfc99cb6ad
ToppCellMS-CD4-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

CDC42BPG PSMB9 GBP1 RNF213 PARP14 HELZ2

2.14e-051521646b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCellfacs-Marrow-KLS-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 SOX15 DSCAM SOX18 ADRB1 FAM107A

2.30e-05154164637765512dfae557b9f6eb30a29463b93682a4404
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CASQ2 IGF2 NFATC4 CSPG4 ATP2A3 ADAP2

2.39e-051551646ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CASQ2 IGF2 NFATC4 CSPG4 ATP2A3 ADAP2

2.39e-0515516460f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CASQ2 IGF2 NFATC4 CSPG4 ATP2A3 ADAP2

2.39e-051551646d8b5145258f075b15080f8739f537f48dd22225e
ToppCellfacs-Thymus-nan-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST14 SULF2 CIITA CD86 EPHA2 ADAP2

3.75e-051681646d72cd8238fa793bb3e4add4c59eaaaadcea9930d
ToppCellfacs-Thymus-nan-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST14 SULF2 CIITA CD86 EPHA2 ADAP2

3.75e-051681646c34c52165485f612add7a3e35a175d5a6e365e7c
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 ATAD2 CREG1 ME2 SULF2 PYGL

3.75e-051681646a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCellfacs-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST14 SULF2 CIITA CD86 EPHA2 ADAP2

3.75e-051681646d2afc097ae1243574210be6a751685f949ea941a
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-mDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MTHFD2 SULF2 CIITA CD86 ADAP2 NCKAP1L

4.28e-051721646cc0e2a45fa74ee19e41612c3615729462474003a
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASQ2 ZNF496 ADCY6 CFAP54 CSPG4 ADAP2

4.42e-051731646d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASQ2 ADCY6 NFATC4 CSPG4 ATP2A3 ADAP2

4.42e-0517316462415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASQ2 ADCY6 NFATC4 CSPG4 ATP2A3 ADAP2

4.42e-0517316462acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASQ2 ZNF496 ADCY6 CFAP54 CSPG4 ADAP2

4.42e-0517316463c852ffe22f4a5b632463086b08c669310684e80
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRIO RNF213 CIITA GAA ADAP2 NCKAP1L

4.56e-051741646d5c22b43531414951666ee7542a66ed9380e2d14
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC42BPG COL7A1 OBSCN SERPINB3 EPHA2 TOP2A

4.56e-051741646207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP1 FRS2 CASQ2 CSPG4 KCNJ12 PNCK

4.71e-051751646d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTNAP1 FRS2 CASQ2 CSPG4 KCNJ12 PNCK

4.71e-051751646cf15465855602ba135752c18755e3e058dbd42ec
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-B_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SBK1 COQ8A CD86 ATP2A3 AGBL1 RASAL1

4.86e-051761646318dc722b95e269002fb01a0feb91c0c8539e150
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-B_cell-B_cell_of_the_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SBK1 COQ8A CD86 ATP2A3 AGBL1 RASAL1

4.86e-051761646f6891006d816309edabe75b2abf60675f2958e55
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

WDR36 KALRN RNF213 PARP14 ARID2 PDCD11

4.86e-0517616463de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDC42BPG MTHFD2 ADCY6 CDKAL1 AXIN1 MPP7

5.02e-051771646f360f7099570d248531897b96e0de282e58f59e9
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

KALRN MTHFD2 CNTNAP1 NFATC4 STARD9 CSPG4

5.34e-051791646342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RIN3 MAP3K3 ADRB1 CIITA CD86 NCKAP1L

5.34e-051791646ce95b601bf17ae8167d382a105384b9e65e9407f
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DMXL2 MTHFD2 CD86 PYGL ADAP2 NCKAP1L

5.86e-051821646d5d6bc16458bc665e7ad6669040d79f73f640044
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DMXL2 MTHFD2 CD86 PYGL ADAP2 NCKAP1L

5.86e-0518216460b59ead4bb4486c7ec2ee90b94ee3a09905612c5
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PSMB9 SULF2 CIITA CD86 RASAL1 NCKAP1L

6.22e-051841646315bb14e848d8e8e4533122047df6f9b89b89d99
ToppCellEndothelial-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

NAP1L3 SOX18 SOX7 FAM107A SORCS3 CDH11

6.41e-051851646ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

DMXL2 WDR36 RNF213 CDKAL1 MAP3K4 CIITA

6.41e-051851646a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-chondrocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SOX9 PEG10 IGF2 NRK CSPG4 IHH

6.61e-05186164680a0a42ca8585cdb1dda57a18c254316a126ee64
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

KALRN SOX18 SULF2 FAM107A CCL16 CDH11

6.80e-051871646e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellControl-Endothelial-VE_Peribronchial|Control / Disease state, Lineage and Cell class

MAGI1 KALRN SOX18 SOX7 FAM107A EXOC3L2

7.01e-051881646f5b7dbc89f992c13280d36a34935be83906b1bc0
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SOX9 TEKT3 MRAS IGF2 CDH2 CDH11

7.01e-051881646116ca07ee4413dcc0e9e5ac99bfee6ed7b7847c6
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST5 DSCAM SULF2 CSPG4 CHST7 ARMH4

7.01e-0518816467471c194276161422326647f09022e94f3d1640c
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST5 DSCAM SULF2 CSPG4 CHST7 ARMH4

7.01e-051881646053c251d3ddbeb866f34565aefca4535517b4387
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX18 FMNL3 SOX7 IGF2 FAM107A EXOC3L2

7.01e-051881646a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 HK1 ANK2 ST14 ADRB1 FAM107A

7.01e-051881646d2d2b6c49448da24f457cedcd213f68841834a99
ToppCellControl-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

MAGI1 KALRN SOX18 SOX7 FAM107A EXOC3L2

7.22e-051891646c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCellControl-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

MAGI1 KALRN SOX18 SOX7 FAM107A CDH11

7.22e-051891646f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCellControl-Myeloid|Control / group, cell type (main and fine annotations)

DMXL2 RIN3 CIITA CD86 ADAP2 NCKAP1L

7.65e-0519116469c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

WDR36 RNF213 PARP14 CDKAL1 CIITA ARID2

7.65e-0519116469454f642c3621370fa23640b631301346b300950
ToppCellControl-Endothelial-VE_Venous|Control / Disease state, Lineage and Cell class

MAGI1 KALRN SOX18 SOX7 FAM107A CDH11

7.65e-051911646617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST5 DSCAM SULF2 CSPG4 CHST7 ARMH4

7.65e-051911646ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST5 DSCAM SULF2 CSPG4 CHST7 ARMH4

7.65e-051911646478e8341ee03b05501e2233e02cef5f97492c95d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PEG10 SORCS3 CDH2 TOP2A RPL15 DCTN3

7.87e-051921646b18ae7337eaad1315a5b0ee81c75f7606bd3c7fe
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

MAGI1 ANK2 OBSCN CASQ2 KLHL7 CDH2

7.87e-051921646ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellCV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

PSMB9 GBP1 RNF213 PARP14 HELZ2 IQCG

7.87e-0519216462a2052b44e8f679ef484f03ba4fb37b0ec841b88
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DMXL2 RIN3 SULF2 CIITA CD86 NCKAP1L

8.10e-05193164658e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SOX9 MAGI1 PEG10 CNTNAP1 C1R CDH11

8.10e-051931646cf2461af78f65616ce40d552ee9452295e3895ed
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

DMXL2 RIN3 CD86 TOP2A ADAP2 NCKAP1L

8.10e-05193164612bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellCOPD-Endothelial|COPD / Disease state, Lineage and Cell class

MAGI1 KALRN SOX18 SOX7 ADRB1 FAM107A

8.10e-051931646093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SOX9 MAGI1 PEG10 CNTNAP1 C1R CDH11

8.10e-0519316466ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 HK1 ANK2 ADCY6 ST14 FAM107A

8.10e-051931646b397c14ac1e34c6be3f25d4417d200bc518d3048
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-myofibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SOX9 MRAS DSCAM PEG10 IGF2 NRK

8.10e-05193164602dfd1df1e7fc84bfca2b0c95138b5b4408bb5d1
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CDC42BPG PEG10 NFATC4 AGBL1 TOP2A MPP7

8.10e-05193164644839a606ae2f8e37421bda46d588189e1c943d2
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SOX9 MAGI1 PEG10 CNTNAP1 C1R CDH11

8.10e-051931646e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MTHFD2 GBP1 RNF213 PARP14 CD86 HELZ2

8.33e-051941646e36d1fd141bdcbd9ed66a33de6cdfde77189a0c1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN SOX18 FMNL3 SULF2 CIITA EXOC3L2

8.33e-051941646e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SOX9 MRAS IGF2 NRK CDH2 CDH11

8.57e-051951646ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

PSMB9 GBP1 RNF213 PARP14 HELZ2 DOP1A

8.57e-051951646b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4|TCGA-Prostate / Sample_Type by Project: Shred V9

RIN3 CNTNAP1 SOX7 SULF2 EPHA2 C1R

8.57e-0519516465562665dd3beb70e2358aa32611a337bef5731c1
ToppCell343B-Endothelial_cells-Endothelial-D|343B / Donor, Lineage, Cell class and subclass (all cells)

SOX18 SOX7 SULF2 FAM107A CHST4 CCL16

8.82e-05196164699953fe0a40e242f6945150345fc0a08ed95f8f9
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_monocytic|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 RIN3 MAP3K3 CD86 GAA ADAP2

8.82e-05196164689ff93cbfbe39fbdf2498e8fdc5d61a0ecb26fc9
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 RIN3 MAP3K3 CD86 GAA ADAP2

8.82e-05196164609574bfeb1d3da53b5471cfb0602946d328b3b5c
ToppCellMesenchymal_cells-Fibro/Chondro_p.|World / Lineage and Cell class

SOX9 CHST5 NRK CSPG4 IHH ARMH4

8.82e-051961646ddc168849e0e97005a111be004463bb72d433853
ToppCell343B-Endothelial_cells-Endothelial-D-|343B / Donor, Lineage, Cell class and subclass (all cells)

SOX18 SOX7 SULF2 FAM107A CHST4 CCL16

8.82e-0519616465edffdc4c1ff35d9ee0e5c1bed0dc0c90b76ea00
Diseaseplatelet component distribution width

RIN3 LNX2 KALRN PSMB9 ZNF496 MPRIP ADRB1 MAVS PDS5A DLEC1 HERC1 EXOC3L2 ALG12 GAA PIF1

1.23e-0575515615EFO_0007984
DiseasePR interval

MAGI1 MRAS KALRN OBSCN ADRB1 COQ8A ARID2 DLEC1 SLC2A11 CBX8

3.19e-0449515610EFO_0004462
DiseaseGlycogen Storage Disease

GYS2 PYGL GAA

3.86e-04271563C0017919
DiseaseHepatoblastoma

AXIN1 IGF2

4.11e-0461562C0206624
Diseaseresting heart rate, chronic obstructive pulmonary disease

RIN3 HERC1 CDH11

5.30e-04301563EFO_0000341, EFO_0004351
Diseaselethal congenital contracture syndrome (is_implicated_in)

CNTNAP1 ADCY6

5.73e-0471562DOID:0060558 (is_implicated_in)
Diseaseintestinal cancer (implicated_via_orthology)

MRE11 SOX15 SOX7

6.42e-04321563DOID:10155 (implicated_via_orthology)
DiseaseVentricular Dysfunction

ADRB1 GAA

7.62e-0481562C0242973
Diseaseglycogen storage disease (is_implicated_in)

GYS2 PYGL

9.76e-0491562DOID:2747 (is_implicated_in)
DiseaseVENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder)

ANK2 CASQ2

1.22e-03101562C1631597
Diseasevenous thromboembolism, response to antineoplastic agent

RIN3 KALRN IQCM

1.33e-03411563EFO_0004286, GO_0097327
Diseaseaortic valve stenosis (is_marker_for)

ADRB1 NFATC1

1.48e-03111562DOID:1712 (is_marker_for)
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPG RNF213

1.48e-03111562DOID:0060669 (implicated_via_orthology)
DiseaseGastric Adenocarcinoma

TRRAP EPHA2 MAP3K9

1.75e-03451563C0278701
DiseaseDisease Exacerbation

COL7A1 EPHA2 CDH2 TOP2A RPL15

1.88e-031651565C0235874
Diseasespontaneous preterm birth

TEKT3 DSCAM KALRN DLEC1

2.06e-031011564EFO_0006917
DiseaseBirth Weight

CDKAL1 ADRB1

2.42e-03141562C0005612
DiseaseDown syndrome (implicated_via_orthology)

DSCAM DOP1A

2.79e-03151562DOID:14250 (implicated_via_orthology)
Diseaseinfant head circumference

CDKAL1 ADRB1

2.79e-03151562EFO_0004577
DiseaseGastro-enteropancreatic neuroendocrine tumor

CIITA CD86

2.79e-03151562C2930967
Diseasecancer (implicated_via_orthology)

AXIN1 SCRIB TOP2A CBX8 PIF1 CDK3

3.10e-032681566DOID:162 (implicated_via_orthology)
DiseaseHypertrophic Cardiomyopathy

OBSCN CASQ2 GAA

3.44e-03571563C0007194
Diseaseinsulin resistance

DOCK1 ANK2 CDKAL1

3.79e-03591563EFO_0002614
Diseasefemoral neck bone mineral density

CDKAL1 AXIN1 SPCS3 IGF2 NFATC1

3.95e-031961565EFO_0007785
Diseaseglucose homeostasis measurement, acute insulin response measurement

CDKAL1 ATP2A3

4.02e-03181562EFO_0006831, EFO_0006896
DiseaseAdrenocortical carcinoma

IGF2 TOP2A

4.02e-03181562C0206686
Diseaseprogression free survival, ovarian carcinoma

FMNL3 ARMH4

4.02e-03181562EFO_0001075, EFO_0004920
Diseasesensorineural hearing loss (implicated_via_orthology)

LNX2 DNAH9

4.48e-03191562DOID:10003 (implicated_via_orthology)
Diseaseosteoporosis (implicated_via_orthology)

IGF2 CIITA

4.48e-03191562DOID:11476 (implicated_via_orthology)
Diseasetype 1 diabetes mellitus (biomarker_via_orthology)

IGF2 ADRB1

4.48e-03191562DOID:9744 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
VKAFHRELVPDRLFV

ADRB1

346

P08588
PDIRQKHVAALLDIR

EXOC3L2

311

Q2M3D2
FIHNPKRQDLEVEVR

ESYT2

591

A0FGR8
EIQRFLRKHLIPDVT

BAAT

401

Q14032
RHLVKRQREPAAAAV

C1orf167

521

Q5SNV9
VEVTTPVHDFLKRRN

CFAP54

1356

Q96N23
EINVKQARLRVDHRP

CNTNAP1

881

P78357
HLPAIIFVTKRNREV

CCL16

61

O15467
FTQEDLRKRRVLFVH

CSPG4

1081

Q6UVK1
ILPKDVAAHFLARER

ADCY6

951

O43306
DEVFSHILKRPDRVL

CIITA

481

P33076
RRRHKVLVGEFAQIR

IQCD

366

Q96DY2
LAFPKIERRREIAHV

ARMH4

26

Q86TY3
FNNRTDRVKVILHPE

GYS2

466

P54840
VRRPAEAEAHRIQQI

FLOT2

286

Q14254
LRTVFPNHTVKRVED

ARID2

571

Q68CP9
LEVRRQGIHQREFKP

DOP1A

2336

Q5JWR5
HREDKVIPVTRSLRA

ATAD2

121

Q6PL18
PVLSEDIDKHRRRFN

DMXL2

2406

Q8TDJ6
IHIPERSDEAQRVFK

CD86

301

P42081
RLIRSFEHRNFKPVV

C2orf76

11

Q3KRA6
EKIAHDLRFVRLPVA

C1R

601

P00736
FARVEPAHKSRIVEN

ATP2A3

676

Q93084
NRKVSVVRALRHAVP

ALG12

201

Q9BV10
QRLLERTKNERAHPV

AGBL1

1001

Q96MI9
VHRNFPDISRVKSVR

ADAP2

51

Q9NPF8
PEIRHRGRFAVEFNK

IQCG

131

Q9H095
FKQLHRRVEERFPQA

RASAL1

441

O95294
KAFHDLVRVIRQQIP

MRAS

166

O14807
PEEIRKRLEHTERQF

RAVER1

41

Q8IY67
RFNDIHVPVRLESVK

PDS5A

331

Q29RF7
VDSKPELQRVLEHRR

FAM107A

61

O95990
APEFIKVRENLRRIA

FAM107A

121

O95990
KRIGPHIEIFQVFRE

IQCM

266

A0A1B0GVH7
VIHAQSRDLPRIFRV

CDC42BPG

1016

Q6DT37
RCHFKRPRELEDAQA

ABCD1

431

P33897
VVFAKSHDPIEARLR

ANK2

1331

Q01484
AVQLHVKEPRLRFTR

OBSL1

331

O75147
PNHRRSQVIEKFEAL

MPRIP

296

Q6WCQ1
QADRKFQEREVPCHR

MAVS

496

Q7Z434
HVNLTVRRKVVFAVP

MAGI1

916

Q96QZ7
AHVRAQLIKPRVTEE

KCNJ12

226

Q14500
RRNVFFPKRRELQIH

FRMD8

126

Q9BZ67
KRVIFHDPDLVEINR

LRRC53

636

A6NM62
NPHDRVVALRRVTAA

HERC1

3166

Q15751
NSPREEIFQVALHKR

LNX2

331

Q8N448
AFVVRQQHVKLARPR

LMTK3

361

Q96Q04
EKQPGHIRSRVFREV

MKNK2

116

Q9HBH9
ERDQQEEKHGPRRRF

MINDY4B

421

A8MYZ0
RRVLDPKDAHVQFRV

PARG

36

Q86W56
DRPVTLVREFIERQH

NDUFB10

36

O96000
ACFIERRKHQNDVRP

KALRN

2956

O60229
KHFQERRLALRRPEI

MPP7

291

Q5T2T1
KNTRVRLVFRVHVPQ

NFATC1

556

O95644
HVFEDPQRREVAKRK

PEG10

156

Q86TG7
PVHREKAEIIRFLTN

NCKAP1L

76

P55160
RATPRHIIVRFTKVE

L1RE1

211

Q9UN81
HRRAEVHKVSRPENE

LSM14A

236

Q8ND56
FVFDRPVHRRKLAQL

GBP1

236

P32455
QERKIPAHRVVLAAA

KLHL7

51

Q8IXQ5
VVNRVFDKLSPLHER

PSMB9

46

P28065
DRLLIEKFIDNPRHI

PCCA

256

P05165
HVAARAPRELVLAKV

MROH1

746

Q8NDA8
RFHKTLRRLVPDSDV

HK1

426

P19367
RQHTKEINDRRARFP

GPR52

231

Q9Y2T5
DRPLQVFHVEVKVRD

PCDHA13

111

Q9Y5I0
FIRHLLERDPQKRFT

PNCK

246

Q6P2M8
SIVRVHARPVRFQEA

OBSCN

3176

Q5VST9
HARPVRFQEALKDLE

OBSCN

3181

Q5VST9
SHFRIEKIERIQNPD

PARP14

1641

Q460N5
NLEPAIFEARRHVVK

PLA2G4E

431

Q3MJ16
PNIVRLLDVVHNERK

CDK3

61

Q00526
EQEKVERRRQVPFHL

EIF3C

661

Q99613
IKAVPEHAARLQRLA

DCTN3

116

O75935
QEQEKVERRRQVPFH

EIF3CL

661

B5ME19
PDAVHRERRRKAQEF

GRID2IP

126

A4D2P6
EISKELHRLNFPRRA

SLC2A11

466

Q9BYW1
TLRVEQKDFPAHRIV

KLHL12

36

Q53G59
AVDTFPARVIKHRAA

CBX8

276

Q9HC52
KVAIPIEDVNRSHLR

DOCK1

496

Q14185
PVFDAGHERRRKEQL

DMAP1

216

Q9NPF5
AAILRRERQQKAPRH

DCST1

611

Q5T197
DRHFVRKDVVPKVRR

CDKAL1

26

Q5VV42
EAPRRIRDVINVFHR

CCNL2

136

Q96S94
RKNRTSVHVPLEARV

FRS2

206

Q8WU20
QERARRPKFADIVSI

EPHA2

856

P29317
IAELRRRQAKEHRPV

FMNL3

971

Q8IVF7
VRVEPQKFAEELIHR

AXIN1

381

O15169
EPAKRLRAEQITVHA

COL6A5

561

A8TX70
LEAFREAKRHRPLIA

IGF2

146

P01344
AKLHQAREELRPVRE

BIN3

156

Q9NQY0
RHQEAKVPVAIRVLD

CDH11

466

P55287
PHLAKIFERVRQSAD

COQ8A

291

Q8NI60
IRSIIPNHADKERFA

DUSP7

111

Q16829
ENRLHFTIKDPANRR

GAA

176

P10253
KIREQRRQFSHRAIP

LARP4

691

Q71RC2
PKIETQDIQALRFHR

ME2

56

P23368
ELVEFVKEHQRPTLR

CASQ2

236

O14958
AEAPRVRAQHRERVT

COL7A1

16

Q02388
RRDPNFEALVRKAIV

DNAH9

2106

Q9NYC9
GEKHRELRLRNYVPE

CCDC12

51

Q8WUD4
PREDAARVARFVTHV

CREG1

51

O75629
RADRQEAPRRVHLFV

HELZ2

2056

Q9BYK8
VEREIPGKRHRLQDF

DLEC1

1436

Q9Y238
VHRDIKPENVLLFDR

SBK1

171

Q52WX2
VTKPLDREQIARFHL

CDH2

221

P19022
PVAQRAVRLAVIEFH

KIFBP

86

Q96EK5
THNPLVNVRVERFKR

MAP3K9

876

P80192
DIHPQFRRKFRVIRA

NTAQ1

121

Q96HA8
LHSQIPREEQRKVFD

DHX9

686

Q08211
FLDREPHRLRAFQVI

IHH

246

Q14623
RIKFEHNGERRIIAF

MAP3K3

46

Q99759
EKFAVERPQAHRLFV

RIN3

911

Q8TB24
RARIALVKNDRPVEF

MAP3K4

556

Q9Y6R4
PFVRDIKNERHVVES

NRK

311

Q7Z2Y5
IRSQDVHIKAVLREP

DSCAM

111

O60469
NERRLQELPGKVHRF

PIF1

436

Q9H611
EEILRLRFPHRVQSK

SZT2

686

Q5T011
AHVRAQLIKPRVTEE

KCNJ18

226

B7U540
KRPYVDEAERLRLQH

SOX7

91

Q9BT81
KNTRVRLVFRVHVPQ

NFATC4

546

Q14934
RPFHLAAVRNEAVVI

MTHFD2

26

P13995
PDKHSLAFVVRIERI

RPL7L1

91

Q6DKI1
HVHLRVPFVAIRNKE

SORCS3

916

Q9UPU3
RVLRKALEHVPNSVR

PRPF6

391

O94906
AFKDRSVPVRLHVSR

SPCS3

31

P61009
VAHSSVFRVLRRPQE

ST6GALNAC6

156

Q969X2
PLQVARECLFHREKR

TEKT3

191

Q9BXF9
AVRETHKRVPEERLQ

NAP1L3

276

Q99457
PEQRARARAHFKELV

SOWAHC

46

Q53LP3
APVRTAKAERRHQER

SCRIB

1456

Q14160
KRPFVEEAERLRVQH

SOX9

151

P48436
KEAVRRHINVSFALP

STARD9

1706

Q9P2P6
VDRVANPKDIIHFFR

MRE11

386

P49959
HEAFNRLLEDPVIKR

SPDYE2B

196

A6NHP3
RETRVDLHLPRFKVE

SERPINB3

276

P29508
DVIVHARPIRTRASK

B3GNT9

256

Q6UX72
LRRFAVPLHVDKNAE

BCO1

356

Q9HAY6
RNFPREVREKLHNFA

ANHX

141

E9PGG2
VHLVRDPRAVFRSRE

CHST4

201

Q8NCG5
RHALPFTKILRVQEV

CHST5

356

Q9GZS9
LKVVQLFRDPRAVHN

CHST7

271

Q9NS84
RVHPNFRLIVIEEKD

RNF213

3141

Q63HN8
DIFERVIHLSLAPKR

PDCD11

1816

Q14690
ERHRHRFEVNPNLIK

CTPS2

476

Q9NRF8
RPFVEEAKRLRARHL

SOX15

96

O60248
VKSIFRVVFHDRRLQ

TFCP2

116

Q12800
EVILIDPFHKAIRRN

RPL15

131

P61313
HEAFNRLLEDPVIKR

SPDYE16

156

A6NNV3
HEAFNRLLEDPVIKR

SPDYE18

196

P0DV79
HEAFNRLLEDPVIKR

SPDYE21

196

A0A494C086
HEAFNRLLEDPVIKR

SPDYE2

196

Q495Y8
HEAFNRLLEDPVIKR

SPDYE5

196

A6NIY4
HEAFNRLLEDPVIKR

SPDYE6

196

P0CI01
ERRLKRIISHPFFND

ST14

691

Q9Y5Y6
RPNRQLERLVSHIKE

RFPL3

91

O75679
RRQRKGYEEVHVPAL

SNRNP200

436

O75643
RHRFLEEFITPIVKV

TOP2A

566

P11388
FIRHLRSRREQEKPH

ZNF496

421

Q96IT1
EPVHVARNLRVDLQR

PSMD5

76

Q16401
HEAFNRLLEDPVIKR

nan

156

A6NJR5
KRPFVEEAERLRVQH

SOX18

131

P35713
HLDRIVALFPKDVDR

PYGL

411

P06737
KRERAELHRPQALVF

UHRF1BP1

596

Q6BDS2
FQKPIVLRILDTHRE

THEGL

31

P0DJG4
PRVEIVQKHNTAARR

TRRAP

3501

Q9Y4A5
ILKLLDTERPVNRFH

SULF2

386

Q8IWU5
PHQIKAEIASRRDRL

WWC3

86

Q9ULE0
ERRKHQNDVRPIRSI

TRIO

3071

O75962
NDIPHVVRFSALKRR

WDR36

81

Q8NI36
AVRVAERNFPHKTVA

GARIN5B

196

Q8N5Q1