Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

GLUL GRIA4 NLGN1 GRIN2A SHANK3 OPHN1 PRKACA UNC13A

2.61e-06921958GO:0051966
GeneOntologyBiologicalProcesspostsynaptic density assembly

PTPRD PTPRS LRRC4B NLGN1 SHANK3

1.60e-05341955GO:0097107
GeneOntologyBiologicalProcesspostsynaptic density organization

PTPRD PTPRS LRRC4B NLGN1 SHANK3 OPHN1

1.78e-05581956GO:0097106
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

GLUL GRIA4 NLGN1 GRIN2A SHANK3 OPHN1 PRKACA UNC13A

3.74e-051321958GO:0035249
GeneOntologyBiologicalProcessregulation of postsynaptic density assembly

PTPRD PTPRS LRRC4B NLGN1

4.09e-05211954GO:0099151
GeneOntologyBiologicalProcesssynaptic membrane adhesion

TAOK2 PTPRD PTPRS LRRC4B NLGN1

4.59e-05421955GO:0099560
GeneOntologyBiologicalProcesspositive regulation of synaptic transmission, glutamatergic

GLUL GRIA4 NLGN1 GRIN2A SHANK3

5.16e-05431955GO:0051968
GeneOntologyBiologicalProcesspostsynaptic specialization organization

PTPRD PTPRS LRRC4B NLGN1 SHANK3 OPHN1

5.68e-05711956GO:0099084
GeneOntologyBiologicalProcesspostsynaptic specialization assembly

PTPRD PTPRS LRRC4B NLGN1 SHANK3

5.78e-05441955GO:0098698
GeneOntologyBiologicalProcessexcitatory synapse assembly

PTPRD PTPRS LRRC4B NLGN1 SHANK3

7.18e-05461955GO:1904861
GeneOntologyBiologicalProcessregulation of mitotic DNA damage checkpoint

MAP3K20 PPP1R10

8.89e-0521952GO:1904289
GeneOntologyBiologicalProcesscarotene metabolic process

BCO1 BCO2

8.89e-0521952GO:0016119
GeneOntologyBiologicalProcesscarotene catabolic process

BCO1 BCO2

8.89e-0521952GO:0016121
GeneOntologyBiologicalProcessterpene catabolic process

BCO1 BCO2

8.89e-0521952GO:0046247
GeneOntologyBiologicalProcessregulation of postsynaptic specialization assembly

PTPRD PTPRS LRRC4B NLGN1

9.84e-05261954GO:0099150
GeneOntologyBiologicalProcessregulation of excitatory synapse assembly

PTPRD PTPRS LRRC4B NLGN1

9.84e-05261954GO:1904889
GeneOntologyBiologicalProcessregulation of postsynaptic density organization

PTPRD PTPRS LRRC4B NLGN1

1.15e-04271954GO:1905874
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

DLGAP2 MAP1A ITPR3 CDKL5 PTPRD OTOF PTPRS GLUL VGF NTF3 GRIA4 NLGN1 GRIN2A SHANK3 OPHN1 PRKACA UNC13A

1.96e-0466319517GO:0050804
GeneOntologyBiologicalProcessprotein K48-linked deubiquitination

USP20 USP5 MINDY1 USP33

2.00e-04311954GO:0071108
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

DLGAP2 MAP1A ITPR3 CDKL5 PTPRD OTOF PTPRS GLUL VGF NTF3 GRIA4 NLGN1 GRIN2A SHANK3 OPHN1 PRKACA UNC13A

2.00e-0466419517GO:0099177
GeneOntologyBiologicalProcessregulation of dendritic spine development

CDKL5 PTPRD PTPRS NLGN1 SHANK3 PALM

2.26e-04911956GO:0060998
GeneOntologyBiologicalProcesspostsynapse assembly

CC2D1A PTPRD PTPRS LRRC4B NLGN1 SHANK3

2.55e-04931956GO:0099068
GeneOntologyBiologicalProcessterpene metabolic process

BCO1 BCO2

2.65e-0431952GO:0042214
GeneOntologyBiologicalProcesstetraterpenoid metabolic process

BCO1 BCO2

2.65e-0431952GO:0016108
GeneOntologyBiologicalProcesscarotenoid metabolic process

BCO1 BCO2

2.65e-0431952GO:0016116
GeneOntologyBiologicalProcessplatelet alpha granule organization

NBEAL2 ZNF385A

2.65e-0431952GO:0070889
GeneOntologyBiologicalProcessneuromuscular synaptic transmission

STAC3 NTF3 NLGN1 RIMBP2

3.60e-04361954GO:0007274
GeneOntologyBiologicalProcesscell junction organization

CDH26 ITGB1BP1 CC2D1A ADD2 PTK7 TAOK2 CDKL5 PTPRD PTPRK PTPRS CAP1 LRRC4B NLGN1 GRIN2A SHANK3 OPHN1 PRKACA PALM PRKCI UNC13A GABRA3

3.76e-0497419521GO:0034330
GeneOntologyBiologicalProcessregulation of postsynapse organization

CC2D1A TAOK2 CDKL5 PTPRD PTPRS LRRC4B NLGN1 SHANK3

3.88e-041851958GO:0099175
GeneOntologyCellularComponentglutamatergic synapse

DLGAP2 EPS15 CC2D1A ADD2 TAOK2 CDKL5 PTPRD PTPRS CAP1 VGF GRIA4 LRRC4B NLGN1 GRIN2A SHANK3 OPHN1 PRKACA PRKCI RIMBP2 UNC13A

8.31e-0581719520GO:0098978
GeneOntologyCellularComponentdendrite

DLGAP2 MAP1A NAP1L4 ITPR3 TAOK2 CDKL5 PTPRK CLIP2 NTF3 GRIA4 NLGN1 GRIN2A ZNF385A SHANK3 OPHN1 PRKACA SKOR1 PALM GABRA3 CYBA

1.60e-0485819520GO:0030425
GeneOntologyCellularComponentdendritic tree

DLGAP2 MAP1A NAP1L4 ITPR3 TAOK2 CDKL5 PTPRK CLIP2 NTF3 GRIA4 NLGN1 GRIN2A ZNF385A SHANK3 OPHN1 PRKACA SKOR1 PALM GABRA3 CYBA

1.65e-0486019520GO:0097447
GeneOntologyCellularComponentsomatodendritic compartment

DLGAP2 MAP1A NAP1L4 PTK7 ITPR3 TAOK2 CDKL5 PTPRK PTPRS GLUL VGF CLIP2 NTF3 GRIA4 NLGN1 GRIN2A ZNF385A SHANK3 OPHN1 PRKACA SKOR1 PALM USP33 GABRA3 CYBA

2.01e-04122819525GO:0036477
GeneOntologyCellularComponentperinuclear region of cytoplasm

ATP7B GALNT1 SPRR3 ITGB1BP1 CMYA5 IRAG1 USP20 MAP3K4 ITPR3 CDKL5 NFKBIE PLA2G4A PLCG2 KAT5 SGK1 UPF2 TNFSF13B PRKACA USP33 CYBA

4.80e-0493419520GO:0048471
GeneOntologyCellularComponentdendritic microtubule

MAP1A CLIP2

5.13e-0441952GO:1901588
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

DLGAP2 PTPRD PTPRS GRIA4 LRRC4B NLGN1 GRIN2A SHANK3 EPB41L2

1.79e-08671399MM15327
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

DLGAP2 PTPRD PTPRS GRIA4 LRRC4B NLGN1 GRIN2A EPB41L2

2.21e-06871398M27617
PathwayREACTOME_NEURONAL_SYSTEM

DLGAP2 PTPRD PTPRS GLUL PLCB2 GRIA4 LRRC4B NLGN1 GRIN2A SHANK3 PRKACA EPB41L2 GABRA3

2.70e-0533513913MM14503
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

PTPRD PTPRS GRIA4 GRIN2A

3.88e-05201394MM15485
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

PTPRD PTPRS GRIA4 GRIN2A

4.76e-05211394M27736
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CC2D1A CASZ1 ITPR3 TAOK2 SLC38A10 EHBP1L1 PTPRS NBEAL2 AHNAK RRP12 HERC2 VPS39 FBRSL1 CEP192 WRAP53 BAHD1 IFNLR1 MADD ZNF263 ZNF592 DUSP16 ZNF516 NINL PALM TNKS1BP1 RAI1 AHNAK2 SYMPK

4.21e-1111051982835748872
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

CCDC134 EPS15 SLCO2B1 USP20 SLC38A10 EHBP1L1 PTPRD NBEAL2 CC2D2A ARAP2 VWA3A AFF3 DDX51 GRIN2A WRAP53 IFNLR1 CAPN11 USP5 USHBP1 ARID2 NINL RIMBP2 TRAF3IP3 MYO15A MINDY1 USP33 DNPEP SYMPK CYBA

1.25e-1012421982930973865
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ZNF143 ELOA2 CASZ1 RYR2 ITPR3 NEK4 EHBP1L1 VTN MAP7D3 FBRSL1 DDX51 ASH2L DNAH12 ARID2 ZNF516 AATF DNAAF1 ARHGAP45 RAI1 AHNAK2

8.70e-106381982031182584
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KCTD9 DLGAP2 EPS15 ARHGAP24 TAOK2 PTPRD PTPRS GLUL HERC2 VGF SIN3B CLIP2 GRIA4 GRIN2A SHANK3 ZNF263 SF3B1 ZNF516 PRKACA PRKCI RIMBP2 UNC13A EPB41L2 RAI1

1.61e-099631982428671696
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

ERCC1 ZNF143 CHML ADD2 PTK7 TAOK2 PTPRS HACE1 UBE2S HERC2 C14orf93 NTF3 AFF3 CCDC51 IFNLR1 USP5 PLEKHG3 ARID2 PALM PRKCI ADAMTS14 ARHGAP45 FBN3 DNPEP

1.32e-0712151982415146197
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

NUP50 ADD2 ITPR3 CDCA2 GANAB PTPRD PTPRK PTPRS AHNAK RRP12 HERC2 HYOU1 CEP192 MADD PPM1B PPP1R10 DUSP16 PRKACA PALM AATF PRKCI SYMPK

1.66e-0710491982227880917
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

NUDT18 DLGAP2 MAP1A ACO2 ADD2 CDKL5 PTPRS GLUL CAP1 HYOU1 CLIP2 GRIN2A SHANK3 OPHN1 MADD USP5 SF3B1 UPF2 PRKACA PALM RIMBP2 TNKS1BP1 CGNL1 UNC13A EPB41L2 DNPEP

1.92e-0714311982637142655
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

NAP1L4 CDCA2 AHNAK PLA2G4A SIN3B ZBTB33 MAP7D3 SF3B1 TNKS1BP1 EPB41L2 AHNAK2

2.86e-072561981133397691
Pubmed

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.

VPS13C SLC38A10 AHNAK MACIR BEND3 PPP1R10 ZNF592 ZNF516 FYB1 MINDY1

5.31e-072171981034048709
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EPS15 VPS13C CC2D1A MARCKSL1 RYR2 CDCA2 CDKL5 TOMM22 AHNAK ARAP2 ZBTB33 MAP7D3 BEND3 CEP192 LIG1 SF3B1 CGNL1 EPB41L2

5.74e-077771981835844135
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DLGAP2 MAP1A ACO2 NAP1L4 MARCKSL1 RYR2 PTK7 TAOK2 CDKL5 TOMM22 GLUL CAP1 RETREG2 GRIA4 LRRC4B GRIN2A SHANK3 MADD SF3B1 PALM UNC13A EPB41L2

6.62e-0711391982236417873
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ITPR3 GANAB AHNAK RRP12 HERC2 CAP1 HYOU1 BEND3 DDX51 USP5 SF3B1 AATF TNKS1BP1 EPB41L2 RAI1 SYMPK

1.21e-066531981622586326
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

VPS13C TAOK2 NBEAL2 VPS39 FBRSL1 BAHD1 ZNF592 ZNF516 NINL PALM TNKS1BP1 PADI2 MINDY1 RAI1

2.38e-065291981414621295
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MAP3K4 GANAB RRP12 TET3 ARAP2 BEND3 CEP192 NLGN1 MADD PPIP5K1 RIMBP2 USP33

4.29e-064071981212693553
Pubmed

A human MAP kinase interactome.

MAP1A MAP3K4 GLUL HERC2 CLIP2 MADD USF3 SF3B1 ARID2 DUSP16 PRKACA CGNL1 EPB41L2

4.90e-064861981320936779
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EPS15 MAP3K20 NAP1L4 MARCKSL1 CASZ1 TAOK2 TOMM22 RRP12 HERC2 SIN3B KAT5 DDX51 ZNF385A WRAP53 ASH2L PPP1R10 ZNF592 PLEKHG3 ARID2 PRKACA AATF DDX28 EPB41L2 CYBA

5.12e-0614971982431527615
Pubmed

Genomic analysis of mouse retinal development.

NUDT18 MARCKSL1 CASZ1 TAOK2 CDCA2 SALL2 PTPRS GLUL SIN3B VTN SGK1 ZNF385A PPP1R10 PPIP5K1 PRKCI TRAF3IP3 PNPLA7 EPB41L2 USP33

5.51e-0610061981915226823
Pubmed

Human transcription factor protein interaction networks.

ZNF143 ACO2 NAP1L4 CC2D1A CDCA2 SALL2 GANAB HOXC11 RRP12 NFKBIE HERC2 SIN3B ZBTB33 KAT5 FBRSL1 BEND3 CEP192 ASH2L ZNF691 ZNF592 ARID2 ZNF516 SYMPK

7.68e-0614291982335140242
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

UBA5 EPS15 ITGB1BP1 MAP3K20 NAP1L4 CC2D1A NEK4 NFKBIE PPP1R35 MACIR FBRSL1 ASH2L MADD PPM1B UPF2 PRKACA AATF PRKCI TNKS1BP1

8.57e-0610381981926673895
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

ZNF143 ELOA2 GALNT1 ACO2 USP20 PTK7 SLC38A10 GANAB TOMM22 PTPRK ALDH1L2 AHNAK GLUL LURAP1 HYOU1 NUCB1 CCDC51 ASH2L LIG1 PNPLA7 ADAMTS14 EPB41L2 DNPEP

9.81e-0614511982330550785
Pubmed

Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.

ITPR3 PLCB2 PLCG2 PRKCI

9.90e-0624198410843712
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

NUP50 EPS15 MAP1A SALL2 AHNAK ZBTB33 PPP1R10 SF3B1 TNKS1BP1 EPB41L2 AHNAK2 SYMPK

1.03e-054441981234795231
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NAP1L4 CC2D1A AHNAK NFKBIE SIN3B ZBTB33 MAP7D3 BEND3 ASH2L PPP1R10 ARID2 TNKS1BP1 SYMPK

1.78e-055491981338280479
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

DLGAP2 CDKL5 GRIA4 LRRC4B GRIN2A SHANK3 TNKS1BP1 GABRA3

1.86e-05197198836604605
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

NUP50 EPS15 MAP1A NAP1L4 CC2D1A AHNAK RRP12 SIN3B ZBTB33 MAP7D3 PPP1R10 SF3B1 ARID2 TNKS1BP1 CGNL1 EPB41L2 AHNAK2

2.79e-059341981733916271
Pubmed

Endogenous cleavage of the Arg-379-Ala-380 bond in vitronectin results in a distinct conformational change which 'buries' Ser-378, its site of phosphorylation by protein kinase A.

VTN PRKACA

3.22e-05219821706595
Pubmed

IL2RA is associated with persistence of rheumatoid arthritis.

MACIR IL2RA

3.22e-052198226350950
Pubmed

Wide long lasting perinuclear Ca2+ release events generated by an interaction between ryanodine and IP3 receptors in canine Purkinje cells.

RYR2 ITPR3

3.22e-052198218586264
Pubmed

The Cardiac Ryanodine Receptor Phosphorylation Hotspot Embraces PKA in a Phosphorylation-Dependent Manner.

RYR2 PRKACA

3.22e-052198231078384
Pubmed

High PKCλ expression is required for ALDH1-positive cancer stem cell function and indicates a poor clinical outcome in late-stage breast cancer patients.

ALDH1A3 PRKCI

3.22e-052198232658903
Pubmed

Hepatic stellate cells are an important cellular site for β-carotene conversion to retinoid.

BCO1 BCO2

3.22e-052198220470748
Pubmed

Cell type-specific expression of beta-carotene 9',10'-monooxygenase in human tissues.

BCO1 BCO2

3.22e-052198215983114
Pubmed

cPLA2-interacting protein, PLIP, causes apoptosis and decreases G1 phase in mesangial cells.

PLA2G4A KAT5

3.22e-052198215985650
Pubmed

Inhibition of IL-6 trans-signaling in the brain increases sociability in the BTBR mouse model of autism.

ITPR3 IL6

3.22e-052198227460706
Pubmed

Evidence for compartmentalization of mammalian carotenoid metabolism.

BCO1 BCO2

3.22e-052198225002123
Pubmed

Bioavailability and provitamin A activity of neurosporaxanthin in mice.

BCO1 BCO2

3.22e-052198237864015
Pubmed

Taurine supplementation: involvement of cholinergic/phospholipase C and protein kinase A pathways in potentiation of insulin secretion and Ca2+ handling in mouse pancreatic islets.

PLCB2 PRKACA

3.22e-052198220591207
Pubmed

Transient expression of the IL-2 receptor alpha-chain in IL-6-induced myeloid cells is regulated by autocrine production of prostaglandin E2.

IL2RA IL6

3.22e-05219821587308
Pubmed

Prognostic significance of pretreatment serum cytokines in classical Hodgkin lymphoma.

IL2RA IL6

3.22e-052198224141626
Pubmed

The absence of IL-6 does not affect Th2 cell development in vivo, but does lead to impaired proliferation, IL-2 receptor expression, and B cell responses.

IL2RA IL6

3.22e-052198210229817
Pubmed

aPKClambda/iota promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.

PRKCI IL6

3.22e-052198219805306
Pubmed

Rapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization.

SLCO2B1 PRKACA

3.22e-052198220159975
Pubmed

Regulatory mechanisms and pathophysiological significance of IP3 receptors and ryanodine receptors in drug dependence.

RYR2 ITPR3

3.22e-052198224285081
Pubmed

Positive association of CC2D1A and CC2D2A gene haplotypes with mental retardation in a Han Chinese population.

CC2D1A CC2D2A

3.22e-052198222023432
Pubmed

Retinal accumulation of zeaxanthin, lutein, and β-carotene in mice deficient in carotenoid cleavage enzymes.

BCO1 BCO2

3.22e-052198228286282
Pubmed

Interleukin-6 and soluble interleukin-2 receptor alpha-markers of inflammation in patients with psoriatic arthritis?

IL2RA IL6

3.22e-052198219327240
Pubmed

AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness.

AHNAK AHNAK2

3.22e-052198220833135
Pubmed

The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.

PTPRD PTPRS

3.22e-05219829566880
Pubmed

Association of serum interleukin-6 and soluble interleukin-2-receptor levels with disease activity status in patients with inflammatory bowel disease: A prospective observational study.

IL2RA IL6

3.22e-052198232470973
Pubmed

Regulatory mechanisms for the production of BAFF and IL-6 are impaired in monocytes of patients of primary Sjögren's syndrome.

TNFSF13B IL6

3.22e-052198222018243
Pubmed

Ablation of carotenoid cleavage enzymes (BCO1 and BCO2) induced hepatic steatosis by altering the farnesoid X receptor/miR-34a/sirtuin 1 pathway.

BCO1 BCO2

3.22e-052198230006135
Pubmed

Functional consequence of protein kinase A-dependent phosphorylation of the cardiac ryanodine receptor: sensitization of store overload-induced Ca2+ release.

RYR2 PRKACA

3.22e-052198217693412
Pubmed

Dysfunctional ryanodine receptors in the heart: new insights into complex cardiovascular diseases.

RYR2 PRKACA

3.22e-052198223507255
Pubmed

Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma.

HOXB2 TET3

3.22e-052198232014008
Pubmed

Supplementation with macular carotenoids improves visual performance of transgenic mice.

BCO1 BCO2

3.22e-052198229742455
Pubmed

Coexpression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.

PRKCI IL6

3.22e-052198221535317
Pubmed

The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

AHNAK AHNAK2

3.22e-052198215007166
Pubmed

Genetic dissection in a mouse model reveals interactions between carotenoids and lipid metabolism.

BCO1 BCO2

3.22e-052198227389691
Pubmed

Loss-of-function mutations in MYO15A and OTOF cause non-syndromic hearing loss in two Yemeni families.

OTOF MYO15A

3.22e-052198237189200
Pubmed

Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.

USP20 USP33

3.22e-052198233792613
Pubmed

PLIP, a novel splice variant of Tip60, interacts with group IV cytosolic phospholipase A(2), induces apoptosis, and potentiates prostaglandin production.

PLA2G4A KAT5

3.22e-052198211416127
Pubmed

Enzymology of vertebrate carotenoid oxygenases.

BCO1 BCO2

3.22e-052198232035229
Pubmed

Genetic ablation of carotene oxygenases and consumption of lycopene or tomato powder diets modulate carotenoid and lipid metabolism in mice.

BCO1 BCO2

3.22e-052198224034573
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

MAP1A ADD2 PRRT3 CLIP2 GRIN2A MADD PALM RIMBP2 TNKS1BP1 GABRA3

3.32e-053471981017114649
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

NUP50 EPS15 MAP3K20 CC2D1A RRP12 PLA2G4A PPP1R10 LIG1 USP5 SF3B1 TNKS1BP1 EPB41L2

3.50e-055031981216964243
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

DLGAP2 MAP1A AHNAK GLUL NLGN1 GRIN2A SHANK3 PRKACA EPB41L2

3.66e-05281198928706196
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MAP3K20 CC2D1A CDCA2 NEK4 AHNAK MACIR ARAP2 MAP7D3 CEP192 MADD PLEKHG3 PRKCI TNKS1BP1 CGNL1 EPB41L2 AHNAK2

3.78e-058611981636931259
Pubmed

Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2.

GRIA4 GRIN2A SHANK3

3.85e-0512198326969129
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

DLGAP2 EPS15 VPS13C ADD2 CDKL5 HERC2 CLIP2 GRIA4 GRIN2A SHANK3 PALM

3.99e-054301981132581705
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

UBA5 CC2D1A ITPR3 EHBP1L1 GANAB AHNAK VTN USP5 TNKS1BP1 AHNAK2

4.53e-053601981033111431
Pubmed

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

NFKBIE MACIR AFF3 RASGRP1 IL2RA AHNAK2

4.58e-05112198624390342
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

VPS13C ACO2 CHML ITPR3 GANAB TOMM22 ALDH1L2 RRP12 HERC2 HYOU1 MAP7D3 BEND3 WRAP53 CCDC51 UPF2 ARID2 PRKACA AATF PRKCI DDX28 USP33 AHNAK2

4.79e-0514961982232877691
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

ERCC1 MAP3K4 ITPR3 CDCA2 RRP12 HERC2 VPS39 ASH2L ZNF592 ARID2 AATF

4.90e-054401981134244565
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ERCC1 CMYA5 BFSP1 PTPRD PTPRK OTOF GLUL HERC2 LURAP1 CLIP2 VPS39 NUCB1 FUZ WRAP53 MADD VPS9D1 SF3B1 ZNF592 PADI2 USP33

4.97e-0512851982035914814
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

NUP50 CASZ1 ITPR3 CDCA2 HOXC11 AHNAK RRP12 TET3 SIN3B C14orf93 KAT5 MAP7D3 BEND3 DDX51 ASH2L PPP1R10 SF3B1 AATF RAI1 SYMPK

5.47e-0512941982030804502
Pubmed

Biological insights from 108 schizophrenia-associated genetic loci.

STAC3 TAOK2 NEK4 PLCB2 GRIN2A SF3B1 MYO15A DDX28 RAI1

6.55e-05303198925056061
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

CCDC134 GALNT1 VPS13C CC2D1A MARCKSL1 SALL2 GANAB NFKBIE GLUL CAP1 HYOU1 VPS39 NUCB1 PPP1R10 AATF EPB41L2 USP33

7.06e-0510071981734597346
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

UBA5 NUP50 EPS15 NAP1L4 CMYA5 EHBP1L1 GANAB AHNAK GLUL PLA2G4A CAP1 HYOU1 COG7 NUCB1 LIG1 USP5 PRKACA TNKS1BP1 EPB41L2 AHNAK2 DNPEP

9.32e-0514551982122863883
Pubmed

Screening for replication of genome-wide SNP associations in sporadic ALS.

GALNT1 NLGN1 UPF2

9.64e-0516198318987618
Pubmed

Mitotic regulator Nlp interacts with XPA/ERCC1 complexes and regulates nucleotide excision repair (NER) in response to UV radiation.

ERCC1 NINL

9.64e-053198226805762
Pubmed

Suppression of Rad leads to arrhythmogenesis via PKA-mediated phosphorylation of ryanodine receptor activity in the heart.

RYR2 PRKACA

9.64e-053198225193703
Pubmed

Identification of novel variants in MYO15A, OTOF, and RDX with hearing loss by next-generation sequencing.

OTOF MYO15A

9.64e-053198231250571
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRD PTPRS

9.64e-053198220139422
Pubmed

Protein kinase A enhances lipopolysaccharide-induced IL-6, IL-8, and PGE₂ production by human gingival fibroblasts.

PRKACA IL6

9.64e-053198222452847
Pubmed

Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin-FAK and uPAR signaling.

VTN IL6

9.64e-053198229222114
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRD PTPRS

9.64e-053198233656439
Pubmed

Liver Injury and Elevated Levels of Interleukins, Interleukin-2 Receptor, and Interleukin-6 Predict the Severity in Patients With COVID-19.

IL2RA IL6

9.64e-053198234970527
Pubmed

Fenretinide inhibits vitamin A formation from β-carotene and regulates carotenoid levels in mice.

BCO1 BCO2

9.64e-053198234742949
Pubmed

Self-regulated alternative splicing at the AHNAK locus.

AHNAK AHNAK2

9.64e-053198221940993
Pubmed

Evolutionary aspects and enzymology of metazoan carotenoid cleavage oxygenases.

BCO1 BCO2

9.64e-053198232061750
Pubmed

HERC2-USP20 axis regulates DNA damage checkpoint through Claspin.

USP20 HERC2

9.64e-053198225355518
Pubmed

β-apo-10'-carotenoids support normal embryonic development during vitamin A deficiency.

BCO1 BCO2

9.64e-053198229892071
Pubmed

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.

PTPRD PTPRS

9.64e-05319829784606
Pubmed

IL-6 induces tumor suppressor protein tyrosine phosphatase receptor type D by inhibiting miR-34a to prevent IL-6 signaling overactivation.

PTPRD IL6

9.64e-053198232602014
Pubmed

Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.

PTPRD PTPRS

9.64e-053198225394468
Pubmed

Cytosolic phospholipase A2α enhances mouse mortality induced by Pseudomonas aeruginosa pulmonary infection via interleukin 6.

PLA2G4A IL6

9.64e-053198225201511
Pubmed

Whole Exome Sequencing Reveals Homozygous Mutations in RAI1, OTOF, and SLC26A4 Genes Associated with Nonsyndromic Hearing Loss in Altaian Families (South Siberia).

OTOF RAI1

9.64e-053198227082237
Pubmed

Lipopolysaccharide-induced biphasic inositol 1,4,5-trisphosphate response and tyrosine phosphorylation of 140-kilodalton protein in mouse peritoneal macrophages.

ITPR3 PLCG2

9.64e-05319829013981
Pubmed

Human Vam6p promotes lysosome clustering and fusion in vivo.

RILP VPS39

9.64e-053198211448994
Pubmed

Retina-driven dephosphorylation of the NR2A subunit correlates with faster NMDA receptor kinetics at developing retinocollicular synapses.

GRIN2A PRKACA

9.64e-053198215590926
InteractionTOP3B interactions

CC2D1A CASZ1 ITPR3 TAOK2 SLC38A10 EHBP1L1 TOMM22 PTPRS NBEAL2 AHNAK RRP12 HERC2 HYOU1 VPS39 FBRSL1 CEP192 WRAP53 BAHD1 IFNLR1 MADD ZNF263 UPF2 ZNF592 DUSP16 ZNF516 PRKACA NINL PALM TNKS1BP1 DDX28 RAI1 AHNAK2 SYMPK

4.77e-06147019533int:TOP3B
InteractionDLG2 interactions

DLGAP2 MAP1A CDKL5 VTN NLGN1 GRIN2A SHANK3

1.59e-05831957int:DLG2
InteractionFBXO41 interactions

PTK7 TAOK2 CDKL5 SHANK3

1.83e-05171954int:FBXO41
Cytoband12q13.3

STAC3 HOXC11 HOXC13 ARHGEF25

7.16e-0551198412q13.3
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ITPR3 CDCA2 PPP1R1C PPP1R35 CEP192 PPP1R10 RIMBP2

2.78e-041811267694
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLA2G4A PLCB2 PLCG2

2.95e-04191263832
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRD PTPRK PTPRS

4.01e-04211263813
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

MAP3K20 MAP3K4 TAOK2

6.01e-04241263654
GeneFamilyEF-hand domain containing

EPS15 RYR2 NUCB1 CAPN11 RASGRP1 NINL EFCC1

8.68e-042191267863
GeneFamilyFibronectin type III domain containing

CMYA5 FNDC1 PTPRD PTPRK PTPRS CSF2RB

8.99e-041601266555
GeneFamilyPhospholipases

PLA2G4A PLCB2 PLCG2

3.11e-03421263467
CoexpressionHARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_28DY_POSITIVE

HIC1 ARHGAP24 ACO2 MAP3K20 CHML PTPRS RRP12 NFKBIE GLUL PLCG2 TET3 LILRB4 SIN3B ZBTB33 KAT5 CLIP2 SGK1 AFF3 ZNF385A CSF2RB SLC2A6 ZNF516 PRKACA IL6 EPB41L2 AHNAK2

2.92e-06125019826M41099
CoexpressionGSE24492_LYVE_NEG_VS_POS_MACROPHAGE_DN

NUDT18 SPRR3 MAP3K20 BFSP1 ARAP2 NLGN1 USF3 BCO2 ARID2 UNC13A

3.12e-0620019810M7873
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELOA2 SLCO2B1 EHBP1L1 GLUL PLCB2 LILRB4 SGK1 VMO1 DNAAF1 ARHGAP45 PADI2 CYBA

4.53e-111851981276fc5bbb71e42c0eb70474efcd3a71a7b2633f24
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELOA2 SLCO2B1 EHBP1L1 GLUL LILRB4 SGK1 VMO1 TNFSF13B DNAAF1 IL6 CYBA

1.05e-091911981179e7089022063c5f2b2f1b27658c62b741f3a037
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARHGAP24 SLCO2B1 LILRB4 SGK1 VMO1 TNFSF13B FYB1 IL6 EPB41L2 CYBA

1.68e-0819319810fc2eb6a7b4f1e687bf37e59e3cd52b14f99ffea4
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARHGAP24 SLCO2B1 GLUL LILRB4 SGK1 ZNF385A VMO1 TNFSF13B PADI2 EPB41L2

2.25e-08199198100d447ca1a77120aac068857ff0ddc2ed6942ed3e
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IRX5 CFAP119 VGF GRIA4 GRIN2A DNAH12 RIMBP2 PNPLA7 UNC13A

5.71e-0816519894b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCellMonocytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

EHBP1L1 AHNAK PLCB2 SLC2A6 TNFSF13B TRAF3IP3 FYB1 ARHGAP45 PADI2

7.38e-0817019894e93b66b3033e6e4d5f6d2f41974623a53108f5e
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Basophil|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TESPA1 LILRB4 CSF2RB SLC2A6 TRAF3IP3 FYB1 IL2RA PADI2 IL6

8.16e-0817219896503e85182eb6e8a40a890e393e9ac5c5350e322
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TESPA1 LILRB4 CSF2RB SLC2A6 TRAF3IP3 FYB1 IL2RA PADI2 IL6

8.16e-0817219893c0bf7200e582ee730af49dcd86446e112226aca
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Basophil|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TESPA1 ALOX15B LILRB4 CSF2RB SLC2A6 FYB1 ARHGAP45 PADI2 IL6

8.58e-0817319898ca650542655c27516029e5bace97ff1b9dcc256
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TESPA1 ALOX15B LILRB4 CSF2RB SLC2A6 FYB1 ARHGAP45 PADI2 IL6

8.58e-0817319894282b47b33325472f52a4085986988911a372ed8
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TESPA1 ALOX15B LILRB4 CSF2RB SLC2A6 PLEKHG3 FYB1 ARHGAP45 PADI2

8.58e-0817319892cba41c3d9d3076f703115d19729073a3ac3feb6
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TESPA1 ALOX15B LILRB4 CSF2RB SLC2A6 PLEKHG3 FYB1 ARHGAP45 PADI2

8.58e-08173198911d69a4ab4a87b8820cd3bd204de8c4124450a90
ToppCellHSPCs-Eo/Baso_prog.|HSPCs / Lineage and Cell class

MARCKSL1 PTPRS PLCB2 CSF2RB DUSP16 FYB1 PADI2 IL6 CYBA

1.52e-0718519891ae29c0077bfc57e8896e59a21f20af43e7ff5b7
ToppCell10x_5'_v1-Non-neoplastic-Myeloid|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARHGAP24 SLCO2B1 GLUL LILRB4 SGK1 ZNF385A TNFSF13B PADI2 EPB41L2

2.70e-071981989e1a0c809302a3b304775bd708201ad412a98d711
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARHGAP24 SLCO2B1 LILRB4 SGK1 TNFSF13B FYB1 PADI2 EPB41L2 CYBA

2.70e-071981989979c391a3b7130e4f91d76a9eb8079fb0f445c4c
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARHGAP24 SLCO2B1 GLUL LILRB4 SGK1 VMO1 TNFSF13B PADI2 EPB41L2

2.82e-07199198945e2f44a0ed39cb9ba061a03874c1fe746856c2d
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARHGAP24 SLCO2B1 GLUL LILRB4 SGK1 VMO1 TNFSF13B PADI2 EPB41L2

2.82e-071991989de9c1c801eb34faf01760df07d5ff6bbd561e152
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TESPA1 ALOX15B LILRB4 CSF2RB SLC2A6 FYB1 ARHGAP45 PADI2

4.83e-071551988c648512305166d2a2f0e284c127bc802af908071
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TESPA1 PLCB2 ALOX15B LILRB4 BAHD1 CSF2RB PLEKHG3 FYB1

6.15e-0716019886393e3d5c5c8176c93aecd89b313bd054a00d474
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TESPA1 PLCB2 ALOX15B LILRB4 BAHD1 CSF2RB PLEKHG3 FYB1

6.15e-0716019882065938e944eb99478fd8132c2c03adeaee6d447
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Basophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ALOX15B LILRB4 CSF2RB SLC2A6 FYB1 ARHGAP45 PADI2 IL6

7.41e-071641988dc22b1fef49c1557a0b63c536eaba574dfcab715
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ALOX15B LILRB4 CSF2RB SLC2A6 FYB1 ARHGAP45 PADI2 IL6

7.41e-071641988f4de9f18134a06f3d7fcf5b50b8e21c1506e2083
ToppCell367C-Myeloid-Dendritic-pDC|367C / Donor, Lineage, Cell class and subclass (all cells)

MAP1A CHML PTPRS LILRB4 AFF3 FUZ CSF2RB ARID2

8.50e-071671988650de8cd5df070639b8aa292aacead739cfdb02c
ToppCellCOVID_vent-Lymphocytic-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

MAP1A PTK7 PTPRS LILRB4 AFF3 IFNLR1 CSF2RB AHNAK2

1.02e-061711988debbb071d260639b16269c94d172766908325c58
ToppCellCOVID_vent-Lymphocytic-Dendritic-pDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

MAP1A PTK7 PTPRS LILRB4 AFF3 IFNLR1 CSF2RB AHNAK2

1.02e-061711988779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NBEAL2 ALOX15B LILRB4 CSF2RB FYB1 ARHGAP45 PADI2 IL6

1.06e-061721988c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NBEAL2 ALOX15B LILRB4 CSF2RB FYB1 ARHGAP45 PADI2 IL6

1.06e-061721988953b05f776348cff784e79c93df65841939d880f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRAG1 FNDC1 LURAP1 NTF3 GRIA4 ARHGEF25 GABRA3

1.33e-06123198787401764a073c1808f214642a9c84299c78f7ec7
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STAC3 LILRB4 VMO1 SLC2A6 TNFSF13B FYB1 IL2RA IL6

1.43e-061791988330c1326ba93bb8f32559ee1cc40e357cc44ad8d
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STAC3 LILRB4 VMO1 SLC2A6 TNFSF13B FYB1 IL2RA IL6

1.43e-061791988dc03b9045510eb1bb934329646bb92dd06890ce9
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX5 TESPA1 ARAP2 MADD RASGRP1 FYB1 ARHGAP45 IL2RA

1.43e-0617919888bf04a7ad1b0be6722ebfdceba3f083f07bf96c5
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NUDT18 CCDC134 TESPA1 ARAP2 TRAF3IP3 FYB1 ARHGAP45 IL2RA

1.49e-061801988702673c0b7c5b0d22a6af3884374804b8c4d6254
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K20 IRAG1 MAMDC2 ARAP2 VTN NTF3 COG7 TNKS1BP1

1.49e-06180198878fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C PTPRS AHNAK ALOX15B CSF2RB FYB1 PADI2 IL6

1.56e-0618119887286700396676fdc41d9723979b8b408177aceb9
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1A MAP3K20 IRAG1 HOXC11 MAMDC2 VTN NTF3 ARHGEF25

1.69e-0618319888de4b616a06be03e1cb6ae6a9ce6bf06485629d3
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 EHBP1L1 PLCB2 LILRB4 SGK1 PPP1R10 PADI2 EPB41L2

1.69e-06183198862f76907e501bba6e1010b5c447faed5f0ef93a7
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TESPA1 ARAP2 MADD RASGRP1 TRAF3IP3 FYB1 ARHGAP45 IL2RA

1.83e-061851988212a8f6fb9eac0c6a89a20a9aa30d48c21abd375
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HOXB2 PPP1R10 RASGRP1 DUSP16 TRAF3IP3 FYB1 ARHGAP45 IL2RA

1.83e-0618519882df3e814859c8f468d203f9d84ecc02e0c5788ad
ToppCellHSPCs-Eo/Baso_prog.|World / Lineage and Cell class

MARCKSL1 PTPRS PLCB2 CSF2RB DUSP16 FYB1 PADI2 IL6

1.83e-061851988b40ea11f5e536438b400ca5fddfd4559789036bd
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HOXB2 PPP1R10 RASGRP1 DUSP16 TRAF3IP3 FYB1 ARHGAP45 IL2RA

1.83e-0618519886bab4fc08bdc3de040bbcc750e1ee30932fcadbe
ToppCellMyeloid-D_(Mast_cell)|World / shred on cell class and cell subclass (v4)

TESPA1 ALOX15B LILRB4 CSF2RB FYB1 PADI2 IL6

1.92e-061301987574e262eb4ed2d69c3da68be061cebac9fefc29e
ToppCell3'_v3-blood-Myeloid_Dendritic|blood / Manually curated celltypes from each tissue

HIC1 MAP1A MARCKSL1 PTPRS LILRB4 AFF3 CSF2RB FBN3

2.07e-061881988239a2162a21d3339da7c1884ab76286346fbf97f
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP24 SLCO2B1 PLCB2 PLCG2 LILRB4 TRAF3IP3 FYB1 CYBA

2.15e-0618919887ac78441a15a82218deaafd47accff2ea5c8de20
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP24 SLCO2B1 PLCB2 PLCG2 LILRB4 TRAF3IP3 FYB1 CYBA

2.15e-061891988389ccb68acb82893709f256315111470cf4beed3
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP24 SLCO2B1 PLCB2 PLCG2 LILRB4 TRAF3IP3 FYB1 CYBA

2.15e-06189198858465b9407fbce91cca8f199950d6e0054c38fbc
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 LILRB4 SGK1 TNFSF13B FYB1 PADI2 IL6 CYBA

2.51e-06193198826a55e98005163122d277480d1d44dd6910ab42f
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLCO2B1 PTK7 PTPRD MAMDC2 NLGN1 ARHGEF25 TNFSF13B GABRA3

2.61e-0619419887826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCellCOVID-19-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

MAP1A PTPRS CFAP119 LILRB4 AFF3 FUZ CSF2RB SLC2A6

2.71e-0619519884a7c080230ce6a79335ecbeadecb0177b2c13625
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 PLCB2 LILRB4 SGK1 TNFSF13B FYB1 PADI2 EPB41L2

2.71e-061951988b6bf75669f267ecdc96818c7022db852e37a9fe1
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 GLUL ALOX15B LILRB4 VMO1 FYB1 PADI2 CYBA

2.71e-0619519889a9e074f7ac04656dccbed2f0df11377e33d3c05
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MAP1A FNDC1 PTPRD PTPRK MAMDC2 AHNAK AFF3 AHNAK2

2.82e-06196198824d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 PLCB2 LILRB4 SGK1 TNFSF13B FYB1 PADI2 EPB41L2

2.82e-061961988e54c08f88779f9fd453a4f5b85aed1f460d8a1e1
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLCO2B1 STAC3 GLUL LILRB4 VMO1 TNFSF13B FYB1 CYBA

2.93e-061971988dc56bb758c7c5bd151be66f8f3b7078d085f72c7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLCO2B1 STAC3 GLUL LILRB4 VMO1 TNFSF13B FYB1 CYBA

2.93e-0619719882efb5acd56b96e5afd8d72b927f1d53cc443766f
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARHGAP24 SLCO2B1 LILRB4 SGK1 FYB1 PADI2 EPB41L2 CYBA

2.93e-061971988769a4203c014b34d16d4d76d3caf07ddb2c41abc
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARHGAP24 SLCO2B1 GLUL LILRB4 SGK1 PADI2 IL6 EPB41L2

3.04e-0619819889aced8bdb56ee52866a0a9766a84336961bc4443
ToppCellfacs-Lung-Endomucin-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXC13 MACIR LILRB4 CSF2RB SLC2A6 FYB1 ARHGAP45

5.42e-061521987962f5bf632da79bd933193d3edd7d89941a85831
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell-SMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAP3K20 IRAG1 AHNAK NTF3 PLEKHG3 ADAMTS14 CYBA

6.99e-0615819875b3d30f92b619f14a7b48502170000fa5783358a
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAP3K20 IRAG1 AHNAK NTF3 PLEKHG3 ADAMTS14 CYBA

6.99e-06158198708806240228c5b780f5aef92ce2c278ae4d797cc
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAP3K20 IRAG1 AHNAK NTF3 PLEKHG3 ADAMTS14 CYBA

6.99e-061581987496b6988f7b3439968351840ae22f56ffa1643f1
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAP3K20 IRAG1 AHNAK VTN PLEKHG3 ADAMTS14 CYBA

8.92e-0616419879eed945e9b0c1ee5fc62724ac2bbbed4267b0678
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAP3K20 IRAG1 AHNAK VTN PLEKHG3 ADAMTS14 CYBA

8.92e-061641987f510f20e37e31b486cdd0e3f597ce4ff00877c5d
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAP3K20 IRAG1 AHNAK VTN PLEKHG3 ADAMTS14 CYBA

8.92e-0616419875c932a462cbf81d029c8d11ec3aea3191529527b
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUSC1 PLCG2 LILRB4 CSF2RB SLC2A6 FYB1 PADI2

9.66e-06166198782fa07632f7e586698fbf37381715b40f9f6ae3a
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUSC1 PLCG2 LILRB4 CSF2RB SLC2A6 FYB1 PADI2

9.66e-0616619870d03926452414f232c77fd15d5f48d148f9fca3b
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l34|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MARCKSL1 OTOF LILRB4 ZNF263 CSF2RB SLC2A6 ARHGAP45

1.04e-05168198784977db9d71e59208727885320cc18d80d064380
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

MAP1A PTK7 PTPRS ALDH1A3 LILRB4 DNAH12 CSF2RB

1.04e-051681987dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCelldroplet-Lung-nan-18m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TESPA1 ALOX15B LILRB4 CSF2RB PADI2 WFDC12 IL6

1.09e-051691987f2e20049a17eee533d49bd5f24a51962d123d132
ToppCellfacs-Pancreas-Endocrine-18m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB2 CSF2RB TNFSF13B TRAF3IP3 FYB1 ARHGAP45 IL2RA

1.09e-0516919870e3d0b71fc21fd1de7034d13895608de5494fad8
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Basophil|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TESPA1 ALOX15B LILRB4 CSF2RB SLC2A6 TRAF3IP3 FYB1

1.09e-051691987b23d0aaa2da333b9c69a7aee862d5a5d2a1bf79b
ToppCellfacs-Pancreas-Endocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB2 CSF2RB TNFSF13B TRAF3IP3 FYB1 ARHGAP45 IL2RA

1.09e-05169198780089dfb1f0f4d6bdf6ca161e902b38011992dfd
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TESPA1 ALOX15B LILRB4 CSF2RB SLC2A6 TRAF3IP3 FYB1

1.09e-05169198783d1bcf33872b01ea9614f608a3e4ab30df25c7e
ToppCellfacs-Pancreas-Endocrine-18m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB2 CSF2RB TNFSF13B TRAF3IP3 FYB1 ARHGAP45 IL2RA

1.09e-051691987c68a305069a149d66dfdeef2a8010f460dc1da3b
ToppCelldroplet-Lung-nan-18m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TESPA1 ALOX15B LILRB4 CSF2RB PADI2 WFDC12 IL6

1.09e-0516919874c6892551e9dec94fc62b3beab1e6d424639a1e9
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Basophil|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ALOX15B LILRB4 CSF2RB SLC2A6 FYB1 PADI2 IL6

1.13e-051701987bca78719c17355772ad6c53ee75e459faf1d089f
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ALOX15B LILRB4 CSF2RB SLC2A6 FYB1 PADI2 IL6

1.13e-05170198740d863554ec98ae43f76511c1112859688846613
ToppCelldroplet-Pancreas-Exocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEBP2 MARCKSL1 AHNAK VTN SGK1 CGNL1 CYBA

1.17e-05171198792ac4cc3d54da2ea8e202aa59c78e8875356649e
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF143 NFKBIE PLCB2 RASGRP1 BCO2 TRAF3IP3 AHNAK2

1.22e-05172198776c06a968d3333441eed103abef1e636a1c3e7a1
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCG2 LILRB4 CSF2RB SLC2A6 FYB1 ARHGAP45 PADI2

1.22e-0517219870457ccc18697aaec44b7c30ae157aae8f48d8785
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BFSP1 MACIR LILRB4 MADD PLEKHG3 ARHGAP45 PADI2

1.26e-0517319873c51e7bda1835c25915e50c801b0d643979971a3
ToppCelldroplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ALOX15B LILRB4 CSF2RB FYB1 ARHGAP45 PADI2 IL6

1.26e-051731987120dd20e8a71f9169a1596b6171df7aa0b96dd15
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BFSP1 MACIR LILRB4 MADD PLEKHG3 ARHGAP45 PADI2

1.26e-051731987a042f78a4c69fcc6b5ca76e9bf01e34cee54c81c
ToppCelldroplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ALOX15B LILRB4 CSF2RB FYB1 ARHGAP45 PADI2 IL6

1.26e-051731987b2c55084ef6dac0e329c2e65c24cfe0045859c30
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STAC3 LILRB4 VMO1 SLC2A6 TNFSF13B FYB1 IL6

1.46e-051771987cdad5a2f672a7f07c05669bfcaf1ec74defd3de7
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TESPA1 PTPRS ALOX15B CSF2RB FYB1 PADI2 IL6

1.46e-051771987c1f838e425ebb04482829b1957e3c1347127e6de
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 NBEAL2 PPP1R1C WRAP53 ZNF691 LIG1 IL2RA

1.46e-051771987f10f77130dbb2c0ad1b436ceb4fb1deac2b0267c
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STAC3 LILRB4 VMO1 SLC2A6 TNFSF13B FYB1 IL6

1.46e-051771987991ae76bb615392d84aeb89886148fa42c1c649c
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP2 MAP1A ADD2 OTOF PRRT3 VGF SHANK3

1.52e-0517819871bddbc083c36657bd6910f7466126ab325e88176
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP2 MAP1A ADD2 OTOF PRRT3 VGF SHANK3

1.52e-051781987a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1A PTPRD VTN PCDHGA4 BEND3 USF3 DNAAF1

1.58e-051791987b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDH26 ATP7B CMYA5 CASZ1 PLCG2 ALDH1A3 RAI1

1.58e-0517919876e965e424eebef50f0202cff75f458be395cfca1
ToppCellCiliated_cells-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

MAP1A USP20 NEK4 ALDH1A3 LKAAEAR1 NLGN1 ZNF691

1.58e-0517919871c41314b6fcfcac8d62034e7037570120d58f20f
ToppCellCiliated_cells-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

MAP1A ALDH1A3 VWA3A LKAAEAR1 ADGB DNAH12 DNAAF1

1.63e-051801987d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCell3'_v3-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

MAP1A CHML PTK7 PTPRS LILRB4 AFF3 FUZ

1.69e-0518119873d7f089fb434fbc989f1fa159e22133ae00b2487
ToppCelltumor_Lung-Myeloid_cells-pDCs|tumor_Lung / Location, Cell class and cell subclass

MAP1A CHML PTPRS CFAP119 LILRB4 FUZ CSF2RB

1.69e-051811987c864ffeb9234b8c29754afc91c85a972889617f4
ToppCellfacs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRAG1 PTPRK ARAP2 VTN COG7 PLEKHG3 IL2RA

1.69e-05181198706174ce9240c9261c0f51a1b0d875335d60722e5
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_1|COVID-19_Severe / Disease condition and Cell class

MAP3K20 OTOF AHNAK RETREG2 USF3 FYB1 ARHGAP45

1.69e-0518119870d07a67e8ee3bca687b378afbc4044434e63556d
ToppCell3'_v3-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

MAP1A MARCKSL1 PTPRS AFF3 SHANK3 CSF2RB FBN3

1.69e-05181198766d890a105f955dca91d6e5e6c730d1a68ee9233
ToppCellfacs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRAG1 PTPRK ARAP2 VTN COG7 PLEKHG3 IL2RA

1.69e-0518119871db1eb7d330a7e5090994007ae287e11f0a74450
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP24 CASZ1 BFSP1 PTK7 ITPR3 PLA2G4A CGNL1

1.69e-05181198722363c5835dd6cef8f895ab9362e0837d92b15b1
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

NFKBIE TET3 MACIR AFF3 RASGRP1 CSF2RB IL2RA DNPEP

1.66e-051701928EFO_0000685, EFO_0007791, EFO_0007837

Protein segments in the cluster

PeptideGeneStartEntry
DPAKKGEVLPEEQGP

UNC13A

1026

Q9UPW8
KETVPPGNGAPDVFQ

USHBP1

106

Q8N6Y0
PAPASLPGGSKEEEE

ZNF385A

181

Q96PM9
APDADELPKGEFDPG

ACO2

526

Q99798
PKKGDAEPESPDNGT

AFF3

346

P51826
DEPEPSPGKENAGLR

FBRSL1

36

Q9HCM7
KPAEPTDVPTVDFGG

BDP1

46

A6H8Y1
LHAGKLPFPPEQGDE

COG7

656

P83436
TLLEGPGDKTQPPEE

ARHGEF25

126

Q86VW2
PFSDPDVEGQLPRKG

CEP68

601

Q76N32
QEELEKGTPEPGPLN

DNPEP

206

Q9ULA0
KGTPEPGPLNAVDER

DNPEP

211

Q9ULA0
FFEDPEGKIELPPSL

ADGB

81

Q8N7X0
EKQERGEPAAEGPAP

CASZ1

1596

Q86V15
EALPPGNFKVSLPDG

ATP7B

316

P35670
ADGKAPRIPQPEEGA

ALDH1L2

206

Q3SY69
PEEGPFTFPNGEAVE

RASGRP1

626

O95267
RPVGDPFDVKTEQGP

ALDH1A3

341

P47895
FGEDDDEVPPGNPKP

ARID2

106

Q68CP9
IPTEGGDFNEFPVPE

CAP1

441

Q01518
PGFKAEGPEVDVNLP

AHNAK

2521

Q09666
PGFKGEGPEVDVNLP

AHNAK

3161

Q09666
PGFKGEGPEVDVNLP

AHNAK

4071

Q09666
PGFKGEGPDVDVSLP

AHNAK

4791

Q09666
PEVDLKGPRLDFEGP

AHNAK

4881

Q09666
PEKPGPKAAEVGDDF

CLIP2

61

Q9UDT6
LVQPGISFPGPAEED

DLGAP2

41

Q9P1A6
LEDTEPEAPLGQPKG

ARAP2

1636

Q8WZ64
KGELFEDPLFPAEPS

CAPN11

76

Q9UMQ6
GLGFSPGPQDTPDKE

FBN3

2651

Q75N90
EPVFVPAPGTNEEDG

BCO2

516

Q9BYV7
PEPGDKSNEPEDAGT

EFCC1

341

Q9HA90
TPVPEDKGQPGEDLR

ADAMTS14

1196

Q8WXS8
VPGGKDDPPLVDAAV

ADAMTS17

326

Q8TE56
DPGSKDPEEDYPKFG

ASH2L

241

Q9UBL3
PFPTKPLEGQAEGDS

NUP50

316

Q9UKX7
PNPEDIIFDGDDKQP

CHML

611

P26374
EDPPGEKVASLPGDF

RAI1

796

Q7Z5J4
IEDAAEPKEPAPPNG

PALM

331

O75781
PPLEPAKLEEIDGFF

QSOX1

166

O00391
KLGGEEEAQPQSPAP

RILP

366

Q96NA2
EDEPQKPEDKGDPEG

IRX5

201

P78411
KPEPKPDIVAGNAGE

OPHN1

756

O60890
PTDEEGFLHPPGEKS

ITPR3

1151

Q14573
KDGFKAQEGPPLAVP

NOBOX

21

O60393
FQGEPAHPEEGRKEP

KASH5

426

Q8N6L0
KLPPPPGECTFEQDE

MAMDC2

501

Q7Z304
FDKLEIPQPDFEVPG

BEND3

536

Q5T5X7
DPEDPGAPQASTEGK

PCDHGA4

6

Q9Y5G9
PDKADPFSFEGPEIV

NAP1L4

231

Q99733
VPEGLAGKQEAEPPR

OTOP3

481

Q7RTS5
DPENGEIKPASKPAG

ELOA2

666

Q8IYF1
EGEPFIDPQTDSKPP

KCTD9

66

Q7L273
VEAPFIPKFKGPGDT

PRKACA

311

P17612
VPPFKPNISGEFGLD

PRKCI

536

P41743
ELPRKDGADAVFPGP

ARHGAP45

31

Q92619
DKPFPLDTAEEGPPS

MAP1A

556

P78559
IKPGPELGGEFPVQD

MADD

1536

Q8WXG6
PPPEFSKDSGFLEEL

IFNLR1

426

Q8IU57
QDGNTEPLPPDSGDK

ZBTB33

131

Q86T24
PGIQDEPPKVRGENF

NUDT18

281

Q6ZVK8
ADFQRPPGAAEPEPK

LILRB4

296

Q8NHJ6
GPTPEKPEEEATLGD

MYO15A

1006

Q9UKN7
KPEEEATLGDPQLPA

MYO15A

1011

Q9UKN7
DDPEVQHGKPDPDIF

PUDP

141

Q08623
KLEEAAPPSDPFRGG

HIC1

296

Q14526
GELPPRKDDSVEPSG

HERC2

56

O95714
KAPEDAGPQPGSYEI

HEBP2

26

Q9Y5Z4
PGPVKEPQEKEDADG

NFKBIE

191

O00221
FNLPKEREAIPGGEP

KAT5

116

Q92993
KPSEEEAAVAAGGPP

CYBA

166

P13498
PEEEKGSQPPPAAES

EPB41L2

41

O43491
LDEDEVPPGVAKPLF

ERCC1

26

P07992
PGAPPQQKGDEADVS

IRAG1

221

Q9Y6F6
GKEGPSDQPPNEFGI

GRIA4

581

P48058
LPFPGAEANSPGKAE

MACIR

16

Q96GV9
SVAGPGKPQEEDQPL

NEK4

641

P51957
EDADDGFPAPPKQLD

FYB1

631

O15117
KGQDQDAASIPPFEP

HACE1

396

Q8IYU2
EGPADLEDPFNPKAQ

DDX28

311

Q9NUL7
VKSLEDEGGPLPESP

DNAH12

166

Q6ZR08
PVPQGEDEVPKASGA

EHBP1L1

316

Q8N3D4
EDEVPKASGAPPAGL

EHBP1L1

321

Q8N3D4
PEDPAPGKAGTAEAV

MINDY1

6

Q8N5J2
QGEERAKGAPATEPP

LKAAEAR1

26

Q8TD35
LQGGPPESPEDESAK

LURAP1

206

Q96LR2
EPGDFVKQDIGGLSP

GABRA3

36

P34903
LEPKQQGDPPVEFAT

PLCG2

876

P16885
FGPVIDGDVIPDDPQ

NLGN1

396

Q8N2Q7
KDLGIPKPFGPQVEE

PADI2

596

Q9Y2J8
EPERGGPAKSAFQPV

NTF3

71

P20783
PEGQLKFHPDTDDVP

NUCB1

416

Q02818
LGAEGPDYDTFPEKP

SLC2A6

6

Q9UGQ3
LEELEKPGAGDPDPS

PNPLA7

366

Q6ZV29
LGSEDPEPKEVNGIP

PTPRS

661

Q13332
EPGPLPEDVFSGRQD

HOXB2

286

P14652
DGPNVKGEFLPNLEP

PAGE3

86

Q5JUK9
PNLEPVKIPEAGEGQ

PAGE3

96

Q5JUK9
EPAPPSQGAEAKGEV

MARCKSL1

66

P49006
GNFEDPVLDGPPQDD

ARHGAP24

586

Q8N264
AKADEDPGANLFPPP

CFAP119

56

A1A4V9
DVLEPVQKPHEGPGE

GALNT1

46

Q10472
PSEKAEAGPEGVAPA

HYOU1

666

Q9Y4L1
SPGPGPEIKNLDQAF

CSF2RB

841

P32927
DAFSPGIKQPEAPEI

CARD6

116

Q9BX69
TFNFDPEPEGSEEKP

CC2D2A

196

Q9P2K1
PPQPNIDGKVLETEG

CGNL1

461

Q0VF96
VNDAEPGSPEAPQGK

DDX51

76

Q8N8A6
EIDGFPIKGPGPFNE

FNDC1

136

Q4ZHG4
PEPPKPAADQDGAEV

BFSP1

586

Q12934
PEEPGPLKESPGEAF

C14orf93

121

Q9H972
KEPPASVAEGGNPEE

CMYA5

1726

Q8N3K9
LEKPNEPVPAVSEGG

DUSP16

316

Q9BY84
IDEADIPPPVAIGKG

CC2D1A

186

Q6P1N0
QAALKPEPGRPGEES

BAHD1

321

Q8TBE0
SQFPGEEKPQASPEG

IL2RA

191

P01589
HFPPLIKDSGGEPEE

MAP3K20

416

Q9NYL2
EAKGEPEAPPASGLA

HOXC11

176

O43248
DKYPEPSGALPGDDL

HOXC13

151

P31276
VEAAPEGSLEAPPKG

MAP7D3

406

Q8IWC1
EPLPQPDFDDKGENL

CDCA2

441

Q69YH5
YEDLEGPEPPEKGFK

CEP192

241

Q8TEP8
EDPGPFPKLIGELFN

CDH26

66

Q8IXH8
PASAEGKEEPPGDRE

DNAAF1

356

Q8NEP3
PEQEDKEGSTFPPVE

C2orf81

556

A6NN90
QSDPFVGSDPFKDDP

EPS15

621

P42566
EFDFNIDPKPSEGPG

CDKL5

416

O76039
TEKEGEDGDQPTTPP

LIG1

171

P18858
VPPEKAEEEAATPGG

SALL2

456

Q9Y467
GDLPEDPQKVPEADG

SLC38A10

571

Q9HBR0
QPAVQPAKEDLGPGD

SLC38A10

586

Q9HBR0
KPGAEPPEEDEGTKR

RYR2

3646

Q92736
DLPDAKDSPGPQPTD

PRRT3

311

Q5FWE3
FTVEPLGDKEPSPEQ

FUZ

311

Q9BT04
FPAPVPPGEDSKDVA

IL6

26

P05231
QQDGKLPFVPPEEEF

ITGB1BP1

96

O14713
EEALQPRGTEKEPPG

LRRC4B

501

Q9NT99
GKADLPPINGPVDVD

OTOF

1101

Q9HC10
DEDVPGPVPVKSLQG

PTPRK

486

Q15262
PGQPLNFKAEPESET

PTPRD

516

P23468
KPTPEEHGPGIDIFT

UPF2

431

Q9HAU5
PDFPEKGPEEINEEL

PLA2G4A

241

P47712
SPRPSKGNEPEYEGD

MAP3K4

431

Q9Y6R4
GESPPLPLDNLGKEF

ALOX15B

31

O15296
DFGVIATFDPKPIPG

GLUL

231

P15104
GAPEPLDGAEPAKES

SKOR1

531

P84550
GGPAPAKVFAPERDE

SKOR1

766

P84550
PNPDAAEEELPFKEG

RIMBP2

866

O15034
GNDGKPEPVLSFLPQ

WRAP53

446

Q9BUR4
DAVPGPKDGSAPEVR

VGF

46

O15240
AEPPNAGDPFKAGEA

NKX1-1

151

Q15270
PSQPGEKRPEEVALG

CCDC51

41

Q96ER9
LFELPGPSQAVKGDP

PLEKHG3

786

A1L390
KDPAEGDGAQPEETP

GANAB

191

Q14697
PNETAPFKPEGELHE

NBEAL2

826

Q6ZNJ1
PPEIDDKRGPNTQGE

PPP1R1C

46

Q8WVI7
KSADGEEAAAVPGPP

PPP1R35

11

Q8TAP8
DPEFTEEPVPNSIGK

SGK1

386

O00141
KNAPPGGDEPLAETE

RETREG2

266

Q8NC44
PPEEKGAFGDAPATE

SIN3B

741

O75182
LFQEAPNGPGAEAPE

TAOK2

316

Q9UL54
PDGEFPGRPQSQAED

SPATA31E1

656

Q6ZUB1
GFSLKVEPPQGIPGD

VMO1

61

Q7Z5L0
DGKGPTEQLVSPEPE

PPM1B

211

O75688
GDIVPKEPEPFGASA

NINL

916

Q9Y2I6
EGGGDEPLNFLDPKV

RRP12

1111

Q5JTH9
KVPDQGFIKFPEPGA

SPRR3

116

Q9UBC9
QPDVFPLFKDKGGPE

AATF

256

Q9NY61
AEPLFVPAPGAKDED

BCO1

456

Q9HAY6
DGQVDVKLPEGPLPE

AHNAK2

736

Q8IVF2
QVDVKLPEGPVPEGA

AHNAK2

896

Q8IVF2
QVDVKLPEGPVPEGA

AHNAK2

2381

Q8IVF2
QVDVKLPEGPVPEGA

AHNAK2

2546

Q8IVF2
QVDVKLPEGPVPEGA

AHNAK2

4031

Q8IVF2
GEKETAPEEPGSPAK

ADD2

581

P35612
AADVLPDGPFPQDEK

CCDC134

86

Q9H6E4
PKVGPLSPDEEADTG

C11orf53

196

Q8IXP5
SPGAGPSEPDEVDKF

ATG4D

51

Q86TL0
PKSFPNEVEPEGTGK

TRAF3IP3

446

Q9Y228
KQEVPVPGDGVEFPS

ZNF516

681

Q92618
GNKDEDVSRPYPEPG

WFDC12

81

Q8WWY7
EAFFEPPPGQGEDVL

ZNF143

451

P52747
KEQSPEPHLPEEGEG

ZNF691

36

Q5VV52
DPVESRGLPGPEDDK

SHANK3

1476

Q9BYB0
GPAGEVPQVPDKETK

SLCO2B1

6

O94956
ERLDPFADGGKTPDP

SF3B1

131

O75533
EEELKNFSGPVPDLP

UBA5

351

Q9GZZ9
SPEPEDPIKDNGFGI

ZNF592

146

Q92610
GDGESQPQFPAVPLE

TNKS1BP1

556

Q9C0C2
QDKSLLPGDDFIPEP

VPS13C

2361

Q709C8
EGDPPFKSQIPKESG

USF3

1171

Q68DE3
FSLEEGPAEEPPSKG

TET3

1606

O43151
GPAEEPPSKGAVKEE

TET3

1611

O43151
PKGKNDAINPEDFPE

PLCB2

191

Q00722
FVKGKDNEPPGPIDN

USP20

831

Q9Y2K6
SGKQEPEAKEAPAGP

SYMPK

1101

Q92797
DPPDGIKVFPNEEDL

UBE2S

26

Q16763
GEPQSPDELLPKGDA

TOMM22

11

Q9NS69
LGQFSQEDPVPPAEG

TESPA1

336

A2RU30
SDEGGKLSPFLPPEI

VPS9D1

116

Q9Y2B5
GLKIFEPPAPGEGNS

TNFSF13B

111

Q9Y275
PESARPEEGKPQDGN

STAC3

211

Q96MF2
EPGALDAKPVESPGD

PPP1R10

371

Q96QC0
VVDKPVPEESEGPGS

PTK7

681

Q13308
EAPAPEVGASKPEGI

VTN

121

P04004
KPVPESGDGERVPEQ

USP5

391

P45974
GIPEIDKPSQEFPEE

PPIP5K1

1406

Q6PFW1
DGDPPGPIDNTKIAV

USP33

866

Q8TEY7
FINEKDPTLPPFEGD

VWA3A

1131

A6NCI4
GPRPSGDKEEQPLQE

TUSC1

181

Q2TAM9
FPAGKTPVPAGEEEG

VPS39

641

Q96JC1
DLGEEPEKPAPSLVG

TRIM16L

331

Q309B1
EGLSPRGPAPGEEKF

ZNF263

286

O14978
DGEKEPGFHLDPPQF

GRIN2A

1121

Q12879