Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity

FUT3 FUT5 FUT6

1.05e-066763GO:0017083
GeneOntologyMolecularFunctionalpha-(1->3)-fucosyltransferase activity

FUT3 FUT5 FUT6

2.93e-068763GO:0046920
GeneOntologyMolecularFunction3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity

FUT3 FUT5

1.43e-052762GO:0017060
GeneOntologyMolecularFunctionfucosyltransferase activity

FUT3 FUT5 FUT6

1.87e-0514763GO:0008417
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

EPHB6 FLT3 ALK NRP1

1.10e-0465764GO:0004714
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A12 SLC12A4 SLC13A1

1.29e-0426763GO:0015296
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

EPHB6 VIPR1 NPR1 FLT3 OPN4 PTPRB AVPR1B IL21R MFSD6 ROBO2 GRIN2D CLEC4M ALK ADGRD1 NRP1

1.51e-0413537615GO:0004888
GeneOntologyMolecularFunctionsymporter activity

SLC6A12 SLC12A4 SLC16A9 SLC13A1 SLC5A3

2.69e-04150765GO:0015293
GeneOntologyMolecularFunctionvascular endothelial growth factor receptor activity

FLT3 NRP1

2.97e-047762GO:0005021
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

EPHB6 FLT3 ALK NRP1

3.11e-0485764GO:0019199
GeneOntologyMolecularFunctionreceptor serine/threonine kinase binding

BMP2 BMP10 CFC1B

3.18e-0435763GO:0033612
GeneOntologyMolecularFunctiondinucleotide phosphatase activity

CILP NUDT17

5.06e-049762GO:0004551
GeneOntologyMolecularFunctionco-receptor binding

BMP2 WNT3A

1.09e-0313762GO:0039706
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A12 SLC12A4 SLC13A1 SLC5A3

1.11e-03119764GO:0015294
GeneOntologyBiologicalProcessfucosylation

FUT3 FUT5 FUT6

3.62e-0518753GO:0036065
GeneOntologyBiologicalProcesspeptide antigen transport

CLEC4M TAP2

3.90e-053752GO:0046968
GeneOntologyBiologicalProcessceramide metabolic process

NEU4 ABCA2 FUT3 FUT5 FUT6

5.74e-05113755GO:0006672
GeneOntologyBiologicalProcessneuron recognition

CNTNAP2 ROBO2 ROBO3 NRP1

6.31e-0559754GO:0008038
GeneOntologyBiologicalProcessregulation of neuron projection development

NEU4 WNT3A ITGA6 ROBO2 XK DIXDC1 ROBO3 ALK CUX1 NRP1

7.18e-056127510GO:0010975
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

VIL1 WNT3A ITGA6 ROBO2 DIXDC1 ROBO3 ALK CUX1 NRP1

7.45e-05494759GO:0031346
GeneOntologyBiologicalProcessregulation of anatomical structure size

VIL1 SLC6A12 NPR1 SLC12A4 AVPR1B WNT3A SCPEP1 XK SVEP1 NRP1

7.79e-056187510GO:0090066
GeneOntologyBiologicalProcesscell recognition

CNTNAP2 ROBO2 CLEC4M FUT3 ROBO3 NRP1

8.42e-05198756GO:0008037
GeneOntologyBiologicalProcessoligosaccharide metabolic process

NEU4 FUT3 FUT5 FUT6

1.23e-0470754GO:0009311
GeneOntologyBiologicalProcessoligosaccharide biosynthetic process

FUT3 FUT5 FUT6

1.93e-0431753GO:0009312
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

VIL1 NEU4 WNT3A ITGA6 ROBO2 XK DIXDC1 ROBO3 ALK CUX1 NRP1

2.30e-048467511GO:0120035
GeneOntologyBiologicalProcessaxon midline choice point recognition

ROBO2 ROBO3

2.71e-047752GO:0016199
GeneOntologyBiologicalProcessregulation of cell projection organization

VIL1 NEU4 WNT3A ITGA6 ROBO2 XK DIXDC1 ROBO3 ALK CUX1 NRP1

2.73e-048637511GO:0031344
GeneOntologyBiologicalProcesscardiac atrium morphogenesis

BMP2 BMP10 CFC1B

2.78e-0435753GO:0003209
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

BMP2 BMP10 ROBO2 CFC1B NRP1

3.03e-04161755GO:0003206
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

EPHB6 VIL1 BMP2 NPR1 FLT3 CILP BMP10 WNT3A CFC1B ALK SVEP1 NRP1 COL1A2

3.18e-0411867513GO:0007167
GeneOntologyBiologicalProcessheart induction

BMP2 ROBO2

3.60e-048752GO:0003129
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

VIL1 BMP2 FRMPD4 BMP10 WNT3A CNTNAP2 ITGA6 ROBO2 DIXDC1 CLEC4M ROBO3 ALK CUX1 NRP1

3.61e-0413667514GO:0051130
GeneOntologyBiologicalProcesskidney development

BMP2 MAGED1 BMP10 ROBO2 CUX1 CYP4A22 NRP1

4.06e-04372757GO:0001822
GeneOntologyBiologicalProcesssphingolipid metabolic process

NEU4 ABCA2 FUT3 FUT5 FUT6

4.55e-04176755GO:0006665
GeneOntologyBiologicalProcessL-fucose catabolic process

FUT5 FUT6

4.62e-049752GO:0042355
GeneOntologyBiologicalProcessfucose catabolic process

FUT5 FUT6

4.62e-049752GO:0019317
GeneOntologyBiologicalProcessregulation of heart morphogenesis

BMP2 ROBO2

4.62e-049752GO:2000826
GeneOntologyBiologicalProcessaxon choice point recognition

ROBO2 ROBO3

4.62e-049752GO:0016198
GeneOntologyBiologicalProcesscardiac atrium development

BMP2 BMP10 CFC1B

4.79e-0442753GO:0003230
GeneOntologyBiologicalProcessrenal system development

BMP2 MAGED1 BMP10 ROBO2 CUX1 CYP4A22 NRP1

5.06e-04386757GO:0072001
GeneOntologyBiologicalProcessL-fucose metabolic process

FUT5 FUT6

5.76e-0410752GO:0042354
GeneOntologyBiologicalProcessprotein O-linked glycosylation

POGLUT1 FUT3 FUT5 FUT6

5.84e-04105754GO:0006493
GeneOntologyBiologicalProcesspattern specification process

BMP2 CDX4 POGLUT1 WNT3A ROBO2 CFC1B FUT6 NRP1

6.39e-04526758GO:0007389
GeneOntologyBiologicalProcessregulation of axonogenesis

WNT3A ROBO2 XK DIXDC1 NRP1

6.76e-04192755GO:0050770
GeneOntologyBiologicalProcessneuron projection development

EPHB6 GDPD5 NEU4 WNT3A CNTNAP2 ITGA6 ROBO2 XK DIXDC1 ROBO3 ALK CUX1 NRP1

6.81e-0412857513GO:0031175
GeneOntologyBiologicalProcessregulation of animal organ morphogenesis

BMP2 MAGED1 WNT3A ROBO2

6.96e-04110754GO:2000027
GeneOntologyBiologicalProcessnegative regulation of insulin-like growth factor receptor signaling pathway

BMP2 CILP

7.02e-0411752GO:0043569
GeneOntologyBiologicalProcessnegative regulation of axon extension involved in axon guidance

WNT3A NRP1

7.02e-0411752GO:0048843
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

EPHB6 VIL1 WNT3A CNTNAP2 ROBO2 XK DIXDC1 ROBO3 CUX1 NRP1

7.39e-048197510GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

EPHB6 VIL1 WNT3A CNTNAP2 ROBO2 XK DIXDC1 ROBO3 CUX1 NRP1

7.89e-048267510GO:0048858
GeneOntologyBiologicalProcesspositive regulation of axonogenesis

WNT3A ROBO2 DIXDC1 NRP1

7.95e-04114754GO:0050772
GeneOntologyCellularComponentcell surface

EPHB6 BMP2 BTN2A2 FLT3 BMP10 WNT3A IL21R CNTNAP2 ITGA6 ROBO2 CFC1B CLEC4M NRP1

1.47e-0411117513GO:0009986
GeneOntologyCellularComponentreceptor complex

VIPR1 BMP2 NPR1 FLT3 PTPRB ITGA6 GRIN2D ALK NRP1

2.28e-04581759GO:0043235
DomainGlyco_transf_10

FUT3 FUT5 FUT6

3.30e-068743PF00852
DomainGlyco_tran_10_N

FUT3 FUT5 FUT6

3.30e-068743PF17039
DomainGlyco_trans_10

FUT3 FUT5 FUT6

3.30e-068743IPR001503
DomainGlyco_tran_10_N

FUT3 FUT5 FUT6

3.30e-068743IPR031481
DomainConA-like_dom

BTN2A2 TRIM4 CNTNAP2 ALK SVEP1 ADGRD1 NRP1

2.56e-05219747IPR013320
DomainFN3

EPHB6 PTPRB IL21R ROBO2 ASTN2 ROBO3

9.23e-05185746SM00060
DomainFN3

EPHB6 PTPRB IL21R ROBO2 ASTN2 ROBO3

1.38e-04199746PS50853
DomainFN3_dom

EPHB6 PTPRB IL21R ROBO2 ASTN2 ROBO3

1.80e-04209746IPR003961
DomainWxxW_domain

CILP MUC5AC

2.30e-046742IPR025155
DomainMucin2_WxxW

CILP MUC5AC

2.30e-046742PF13330
Domain-

EPHB6 BTN2A2 FLT3 PTPRB CILP IL21R SIGLEC10 ROBO2 ASTN2 ROBO3

2.75e-0466374102.60.40.10
Domainaa-tRNA-synth_Ia

MARS2 IARS1

3.21e-047742IPR002300
DomaintRNA-synt_1

MARS2 IARS1

3.21e-047742PF00133
DomainIg-like_fold

EPHB6 BTN2A2 FLT3 PTPRB CILP IL21R SIGLEC10 ROBO2 ASTN2 ROBO3

4.51e-047067410IPR013783
DomainEphrin_rec_like

EPHB6 SVEP1

8.32e-0411742PF07699
Domain-

MARS2 IARS1

8.32e-04117421.10.730.10
DomainInhibin_asu

BMP2 BMP10

1.17e-0313742IPR002405
Domainp53-like_TF_DNA-bd

FUT3 FUT5 FUT6

1.21e-0353743IPR008967
DomaintRNAsynth_Ia_anticodon-bd

MARS2 IARS1

1.57e-0315742IPR009080
DomainPkinase_Tyr

EPHB6 NPR1 FLT3 ALK

1.72e-03129744PF07714
DomainMAM_1

ALK NRP1

1.79e-0316742PS00740
DomainSer-Thr/Tyr_kinase_cat_dom

EPHB6 NPR1 FLT3 ALK

2.20e-03138744IPR001245
DomainMAM

ALK NRP1

2.27e-0318742PF00629
Domainaa-tRNA-synth_I_CS

MARS2 IARS1

2.27e-0318742IPR001412
DomainMAM_dom

ALK NRP1

2.27e-0318742IPR000998
DomainMAM_2

ALK NRP1

2.27e-0318742PS50060
DomainAA_TRNA_LIGASE_I

MARS2 IARS1

2.54e-0319742PS00178
Domain-

EPHB6 CNTNAP2 NRP1

3.04e-03737432.60.120.260
DomainFA58C

CNTNAP2 NRP1

3.10e-0321742SM00231
DomainFA58C_3

CNTNAP2 NRP1

3.10e-0321742PS50022
DomainFA58C_1

CNTNAP2 NRP1

3.10e-0321742PS01285
DomainFA58C_2

CNTNAP2 NRP1

3.10e-0321742PS01286
Domainfn3

EPHB6 PTPRB ROBO2 ROBO3

3.92e-03162744PF00041
DomainF5_F8_type_C

CNTNAP2 NRP1

4.04e-0324742PF00754
DomainFA58C

CNTNAP2 NRP1

4.04e-0324742IPR000421
DomainEphrin_rec_like

EPHB6 SVEP1

4.38e-0325742SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

EPHB6 SVEP1

4.38e-0325742IPR011641
DomainTGFb_propeptide

BMP2 BMP10

5.48e-0328742PF00688
DomainTGF-b_N

BMP2 BMP10

5.48e-0328742IPR001111
DomainGalactose-bd-like

EPHB6 CNTNAP2 NRP1

6.18e-0394743IPR008979
Domain-

CNTNAP2 SVEP1 ADGRD1

6.37e-03957432.60.120.200
DomainIG

BTN2A2 FLT3 CILP SIGLEC10 ROBO2 ROBO3

6.46e-03421746SM00409
DomainIg_sub

BTN2A2 FLT3 CILP SIGLEC10 ROBO2 ROBO3

6.46e-03421746IPR003599
DomainIg_I-set

CILP SIGLEC10 ROBO2 ROBO3

6.86e-03190744IPR013098
DomainI-set

CILP SIGLEC10 ROBO2 ROBO3

6.86e-03190744PF07679
DomainTGF-beta-rel

BMP2 BMP10

7.11e-0332742IPR015615
DomainTGFb_CS

BMP2 BMP10

7.11e-0332742IPR017948
PathwayKEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS

FUT3 FUT5 FUT6

6.92e-075593M47966
PathwayKEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS

FUT3 FUT5 FUT6

1.38e-066593M47967
PathwayREACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS

FUT3 FUT5 FUT6

8.78e-0521593M27917
PathwayKEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES

FUT3 FUT5 FUT6

1.69e-0426593M17377
Pubmed

Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms.

FUT3 FUT5 FUT6

1.00e-0837637650030
Pubmed

Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines.

FUT3 FUT5 FUT6

1.00e-08376330808544
Pubmed

Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells.

FUT3 FUT5 FUT6

4.00e-08476319349624
Pubmed

Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.

FUT3 FUT5 FUT6

1.00e-07576329593094
Pubmed

Robo1 modulates proliferation and neurogenesis in the developing neocortex.

ITGA6 ROBO2 ROBO3 CUX1

3.56e-072776424741061
Pubmed

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.

ROBO2 ROBO3 NRP1

4.48e-061576318345009
Pubmed

Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism.

FUT3 FUT5 FUT6

4.48e-061576311698403
Pubmed

Wnt/β-catenin pathway regulates bone morphogenetic protein (BMP2)-mediated differentiation of dental follicle cells.

BMP2 WNT3A

4.71e-06276222150562
Pubmed

Wnt signaling stabilizes the DIXDC1 protein through decreased ubiquitin-dependent degradation.

WNT3A DIXDC1

4.71e-06276220085589
Pubmed

Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes.

FUT5 FUT6

4.71e-0627621339443
Pubmed

Epigenetic modifications and canonical wingless/int-1 class (WNT) signaling enable trans-differentiation of nonosteogenic cells into osteoblasts.

BMP2 WNT3A

4.71e-06276224867947
Pubmed

Down-regulation of FUT3 and FUT5 by shRNA alters Lewis antigens expression and reduces the adhesion capacities of gastric cancer cells.

FUT3 FUT5

4.71e-06276221978830
Pubmed

Correlation of FUT3 and FUT6 Gene Polymorphisms With Helicobacter pylori Infection.

FUT3 FUT6

4.71e-06276239108208
Pubmed

Mesenchymal Stem Cells Within Gelatin/CaSO4 Scaffolds Treated Ex Vivo with Low Doses of BMP-2 and Wnt3a Increase Bone Regeneration.

BMP2 WNT3A

4.71e-06276226414873
Pubmed

Site-specific fucosylation of sialylated polylactosamines by alpha1,3/4-fucosyltransferases-V and -VI Is defined by amino acids near the N terminus of the catalytic domain.

FUT5 FUT6

4.71e-06276217604274
Pubmed

Acceptor specificity of different length constructs of human recombinant alpha 1,3/4-fucosyltransferases. Replacement of the stem region and the transmembrane domain of fucosyltransferase V by protein A results in an enzyme with GDP-fucose hydrolyzing activity.

FUT3 FUT5

4.71e-0627627721776
Pubmed

Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.

FLT3 WNT3A

4.71e-06276215650056
Pubmed

Concerted involvement of Cdx/Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone.

CDX4 WNT3A ITGA6

5.50e-061676321752936
Pubmed

Man1, an inner nuclear membrane protein, regulates left-right axis formation by controlling nodal signaling in a node-independent manner.

BMP2 WNT3A CFC1B

6.67e-061776318697220
Pubmed

Chromatin remodelling complex dosage modulates transcription factor function in heart development.

BMP2 BMP10 ROBO2

6.67e-061776321304516
Pubmed

FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections.

ROBO2 CUX1 NRP1

1.11e-052076330392794
Pubmed

Early dorsomedial tissue interactions regulate gyrification of distal neocortex.

BMP2 WNT3A CUX1

1.30e-052176331729356
Pubmed

Cardiovascular and hematopoietic defects associated with Notch1 activation in embryonic Tie2-expressing populations.

BMP2 FLT3 BMP10

1.30e-052176318617694
Pubmed

Robo family of proteins exhibit differential expression in mouse spinal cord and Robo-Slit interaction is required for midline crossing in vertebrate spinal cord.

ROBO2 ROBO3

1.41e-05376215768400
Pubmed

PDZRN3 negatively regulates BMP-2-induced osteoblast differentiation through inhibition of Wnt signaling.

BMP2 WNT3A

1.41e-05376220668165
Pubmed

Rig-1 a new member of Robo family genes exhibits distinct pattern of expression during mouse development.

ROBO2 ROBO3

1.41e-05376214678835
Pubmed

Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion.

ROBO2 ROBO3

1.41e-05376218466743
Pubmed

Development of immunohistochemistry assays to assess GALNT14 and FUT3/6 in clinical trials of dulanermin and drozitumab.

FUT3 FUT6

1.41e-05376220179215
Pubmed

The Retinal Basis of Light Aversion in Neonatal Mice.

OPN4 TRPC7

1.41e-05376235396331
Pubmed

Cross-talk between Wnt and bone morphogenetic protein 2 (BMP-2) signaling in differentiation pathway of C2C12 myoblasts.

BMP2 WNT3A

1.41e-05376216150699
Pubmed

Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients.

BMP2 BMP10

1.41e-05376224551273
Pubmed

Wnt3a stimulates Mepe, matrix extracellular phosphoglycoprotein, expression directly by the activation of the canonical Wnt signaling pathway and indirectly through the stimulation of autocrine Bmp-2 expression.

BMP2 WNT3A

1.41e-05376222213482
Pubmed

Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways.

BMP2 WNT3A

1.41e-05376219139264
Pubmed

Physical maps of human alpha (1,3)fucosyltransferase genes FUT3-FUT6 on chromosomes 19p13.3 and 11q21.

FUT5 FUT6

1.41e-0537627782074
Pubmed

Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts.

BMP2 WNT3A

1.41e-05376223032104
Pubmed

Effect of rhBMP-2 on the osteogenic potential of bone marrow stromal cells from an osteogenesis imperfecta mouse (oim).

BMP2 COL1A2

1.41e-0537629213002
Pubmed

Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities.

FUT3 FUT5

1.41e-0537621740457
Pubmed

Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.

ROBO2 ROBO3 NRP1

1.72e-052376324360543
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

BMP2 ITGA6 ROBO2 ALK CUX1 NRP1

1.91e-0525176629031500
Pubmed

Molecular basis of Wnt activation via the DIX domain protein Ccd1.

WNT3A DIXDC1

2.82e-05476221189423
Pubmed

Evidence for the existence of two Robo3 isoforms with divergent biochemical properties.

ROBO2 ROBO3

2.82e-05476216226035
Pubmed

Cdx4 is a direct target of the canonical Wnt pathway.

CDX4 WNT3A

2.82e-05476216309666
Pubmed

Secretoneurin induces airway mucus hypersecretion by enhancing the binding of EGF to NRP1.

MUC5AC NRP1

2.82e-05476224556756
Pubmed

Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits.

OPN4 TRPC7

2.82e-05476230017393
Pubmed

Long wavelength light reduces the negative consequences of dim light at night.

OPN4 CNTNAP2

2.82e-05476236493974
Pubmed

Crucial roles of Robo proteins in midline crossing of cerebellofugal axons and lack of their up-regulation after midline crossing.

ROBO2 ROBO3

2.82e-05476218986510
Pubmed

Relative positions of two clusters of human alpha-L-fucosyltransferases in 19q (FUT1-FUT2) and 19p (FUT6-FUT3-FUT5) within the microsatellite genetic map of chromosome 19.

FUT3 FUT6

2.82e-0547627656588
Pubmed

Regulation of matrix metalloproteinase-13 and tissue inhibitor of matrix metalloproteinase-1 gene expression by WNT3A and bone morphogenetic protein-2 in osteoblastic differentiation.

BMP2 WNT3A

2.82e-05476216368545
Pubmed

miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway.

FUT5 FUT6

2.82e-05476228771224
Pubmed

Multiple roles for slits in the control of cell migration in the rostral migratory stream.

ROBO2 ROBO3

2.82e-05476214960623
Pubmed

The slit receptor Rig-1/Robo3 controls midline crossing by hindbrain precerebellar neurons and axons.

ROBO2 ROBO3

2.82e-05476215233918
Pubmed

NRP-1 interacts with GIPC1 and α6/β4-integrins to increase YAP1/∆Np63α-dependent epidermal cancer stem cell survival.

ITGA6 NRP1

2.82e-05476229755126
Pubmed

Genetic analyses of roundabout (ROBO) axon guidance receptors in autism.

ROBO2 ROBO3

2.82e-05476218270976
Pubmed

Expression patterns of Slit and Robo family members during vertebrate limb development.

ROBO2 ROBO3

2.82e-05476211472852
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

ROBO2 ROBO3 NRP1

3.16e-052876318617019
Pubmed

The transcription factor gene Nfib is essential for both lung maturation and brain development.

ROBO2 ROBO3 NRP1

3.90e-053076315632069
Pubmed

The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.

ROBO2 ROBO3

4.69e-05576215084255
Pubmed

Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits.

OPN4 TRPC7

4.69e-05576221261756
Pubmed

Axin contains three separable domains that confer intramolecular, homodimeric, and heterodimeric interactions involved in distinct functions.

WNT3A DIXDC1

4.69e-05576215579909
Pubmed

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

BMP2 CDX4

4.69e-0557627657163
Pubmed

Phosphorylation of the CCAAT displacement protein (CDP)/Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2).

CCNA1 CUX1

4.69e-05576211584018
Pubmed

A molecular basis for retinoic acid-induced axial truncation.

CDX4 WNT3A

4.69e-0557629882496
Pubmed

A dishevelled-1/Smad1 interaction couples WNT and bone morphogenetic protein signaling pathways in uncommitted bone marrow stromal cells.

BMP2 WNT3A

4.69e-05576216621789
Pubmed

Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies.

PTPRB SVEP1

4.69e-05576234663817
Pubmed

Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay.

ROBO2 ROBO3

4.69e-05576223746841
Pubmed

Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate.

BMP2 WNT3A

4.69e-05576219736317
Pubmed

Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program.

BMP2 BMP10 COL1A2

4.75e-053276330936179
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

VIPR1 SLC6A12 NPR1 CNTNAP2 ASTN2 NRP1

5.16e-0530076619086053
Pubmed

Autocrine/juxtaparacrine regulation of axon fasciculation by Slit-Robo signaling.

ROBO2 ROBO3

7.03e-05676222306607
Pubmed

Robo1 and robo2 control the development of the lateral olfactory tract.

ROBO2 NRP1

7.03e-05676217360927
Pubmed

Robo2 Receptor Gates the Anatomical Divergence of Neurons Derived From a Common Precursor Origin.

ROBO2 ROBO3

7.03e-05676234249921
Pubmed

Effect of BMPs and Wnt3a co-expression on the osteogenetic capacity of osteoblasts.

BMP2 WNT3A

7.03e-05676227633082
Pubmed

The role of Robo3 in the development of cortical interneurons.

ROBO2 ROBO3

7.03e-05676219366869
Pubmed

Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain.

ROBO2 ROBO3

7.03e-05676216690755
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

VIPR1 NPR1 PTPRB ALK

7.32e-0510176423382219
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

VIPR1 CPAMD8 POGLUT1 PTPRB SLC16A9 ANKIB1 TNRC6B ASTN2 CEP170B ADGRD1 CUX1 NRP1

8.89e-051489761228611215
Pubmed

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.

EPHB6 FLT3 ALK

9.35e-054076330898150
Pubmed

Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.

FUT3 FUT6

9.83e-05776221203500
Pubmed

Cdx2 and the Brm-type SWI/SNF complex cooperatively regulate villin expression in gastrointestinal cells.

VIL1 CDX4

9.83e-05776219371634
Pubmed

Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs.

OPN4 TRPC7

9.83e-05776238109525
Pubmed

Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype.

BMP2 WNT3A

9.83e-05776224006258
Pubmed

Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.

NPR1 NRP1

9.83e-05776210520994
Pubmed

A tug of war between DCC and ROBO1 signaling during commissural axon guidance.

ROBO2 ROBO3

9.83e-05776237149867
Pubmed

Regulation of skeletal progenitor differentiation by the BMP and retinoid signaling pathways.

BMP2 COL1A2

9.83e-05776210684250
Pubmed

VEGF mediates commissural axon chemoattraction through its receptor Flk1.

ROBO3 NRP1

1.31e-04876221658588
Pubmed

Slit2 and Robo3 modulate the migration of GnRH-secreting neurons.

ROBO2 ROBO3

1.31e-04876222912413
Pubmed

Temporal regulation of axonal repulsion by alternative splicing of a conserved microexon in mammalian Robo1 and Robo2.

ROBO2 ROBO3

1.31e-04876231392959
Pubmed

BMPER regulates cardiomyocyte size and vessel density in vivo.

BMP2 BMP10

1.31e-04876223200275
Pubmed

Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling.

BMP2 BMP10

1.31e-04876217460765
Pubmed

Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses.

BMP2 BMP10

1.31e-04876216049014
Pubmed

An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.

PTPRB WNT3A

1.31e-04876221559415
Pubmed

Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord.

ROBO2 ROBO3

1.31e-04876230893602
Pubmed

Targeting of bone morphogenetic protein growth factor complexes to fibrillin.

BMP2 BMP10

1.31e-04876218339631
Pubmed

Tcf7l2 plays crucial roles in forebrain development through regulation of thalamic and habenular neuron identity and connectivity.

WNT3A ROBO2 ROBO3

1.52e-044776328219675
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

VIPR1 MRPS18B CNTNAP2 LRRC61 XK CUX1

1.65e-0437176615747579
Pubmed

Neutral Sphingomyelinase 2 (SMPD3) Deficiency in Mice Causes Chondrodysplasia with Unimpaired Skeletal Mineralization.

BMP2 COL1A2

1.68e-04976231199918
Pubmed

Axon fasciculation in the developing olfactory nerve.

ROBO2 NRP1

1.68e-04976220723208
Pubmed

Cooperative slit and netrin signaling in contralateralization of the mouse trigeminothalamic pathway.

ROBO2 ROBO3

1.68e-04976222806432
Pubmed

Multi-ethnic genetic association study of carotid intima-media thickness using a targeted cardiovascular SNP microarray.

NPR1 COL1A2

1.68e-04976219679847
Pubmed

Collaborative and specialized functions of Robo1 and Robo2 in spinal commissural axon guidance.

ROBO2 ROBO3

1.68e-04976220631173
GeneFamilyFucosyltransferases|Blood group antigens

FUT3 FUT5 FUT6

1.02e-0513613434
GeneFamilyFibronectin type III domain containing

EPHB6 PTPRB ROBO2 ASTN2 ROBO3

2.03e-04160615555
GeneFamilyADAM metallopeptidase domain containing|CD molecules

FLT3 IL21R ITGA6 CLEC4M FUT3 ALK NRP1

3.51e-04394617471
GeneFamilyBone morphogenetic proteins|Astacins

BMP2 BMP10

6.04e-0411612455
GeneFamilyAminoacyl tRNA synthetases, Class I

MARS2 IARS1

1.85e-0319612131
GeneFamilyGlycosyltransferase family 6|Blood group antigens

XK FUT3

6.91e-0337612454
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

BTN2A2 SIGLEC10

8.04e-0340612592
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FLT3 ALK

8.04e-0340612321
GeneFamilySolute carriers

SLC6A12 SLC12A4 SLC16A9 SLC13A1 SLC5A3

1.06e-02395615752
CoexpressionLAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2

SLC16A9 SLC13A1 ANKIB1 TNRC6B ASTN2 CUX1 NRP1

3.68e-06221767M39222
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#2

ABCA2 DTX4 MFSD6 MAMLD1 CNTNAP2 ASTN2 ACSS2 EFCAB7

2.66e-06248758Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

VIL1 NEU4 SLC16A9 SLC13A1 FUT3 FUT6 CYP4A22

4.53e-081967674ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

GDPD5 FLT3 TRPC7 MAGED1 FRMPD4 GRIN2D

4.21e-071677669efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

GDPD5 FLT3 TRPC7 MAGED1 FRMPD4 GRIN2D

4.21e-07167766904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-mature_conventional_dendritic_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC6A12 NPR1 FLT3 SLC16A9 AVPR1B CCNA1

4.84e-07171766d934d68efc5739483c735dc702ccd30b07a6aa7e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VIL1 NEU4 SLC16A9 SLC13A1 FUT3 FUT6

5.73e-071767661595dbeee336a81e581325d63208ec6262664ee9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A12 SLC16A9 SLC13A1 FUT3 ACSS2 FUT6

5.92e-071777662f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VIL1 SLC16A9 SLC13A1 FUT6 CUX1 NRP1

6.97e-071827664a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A12 NEU4 SLC16A9 SLC13A1 FUT3 FUT6

7.20e-0718376685446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A12 SLC16A9 SLC13A1 FUT3 ACSS2 FUT6

7.43e-071847669434731f651820b05335085582960f08fbf895de
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A12 SLC16A9 SLC13A1 ACSS2 FUT6 CUX1

7.92e-07186766a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VIL1 NEU4 SLC16A9 SLC13A1 FUT6 CYP4A22

9.53e-071927663e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPHB6 FLT3 CNTNAP2 ROBO2 ASTN2 ALK

9.82e-071937662189da4b727e25e62669d7b9257f06493be21a27
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR1 BMP2 NPR1 PTPRB ROBO2 NRP1

9.82e-071937662483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GDPD5 FLT3 CNTNAP2 ASTN2 GRIN2D ALK

9.82e-0719376653bcd50892c379b2a571751f6eb1062436339fe7
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPHB6 FLT3 CNTNAP2 ROBO2 ASTN2 ALK

9.82e-071937663ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GDPD5 NPR1 CDX4 PTPRB ITGA6 NRP1

1.04e-06195766752a100297c26732e12bbbf3ab27a2bd4f5ea06d
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)|Neuronal / cells hierarchy compared to all cells using T-Statistic

GDPD5 FLT3 CNTNAP2 ASTN2 GRIN2D ALK

1.21e-062007661276bfa911fddada4235e12e3081baa53164574b
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

EPHB6 FLT3 CNTNAP2 ROBO2 ASTN2 ALK

1.21e-06200766347a510755374c6a66acee326565dfc447993f18
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPR1 CILP SCPEP1 SVEP1 ADGRD1 COL1A2

1.21e-06200766f6cf98aad53aa8b3fa02cf874d6f7cd75530a213
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Neuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

EPHB6 VIPR1 CNTNAP2 CUX1 NRP1

2.81e-0612976564768adf23123b92280fb30eb85147cbee084ae0
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

TRPC7 MAGED1 FRMPD4 FAM227A GRIN2D

5.69e-061497656e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

VIL1 TRPC7 SLC13A1 FUT6 CYP4A22

6.69e-0615476589a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

VIL1 TRPC7 SLC13A1 FUT6 CYP4A22

6.69e-06154765f1fea1a87e977221fa125b62287368be9af4987d
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

VIL1 TRPC7 SLC13A1 FUT6 CYP4A22

6.69e-06154765b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

VIL1 TRPC7 SLC13A1 FUT6 CYP4A22

6.69e-06154765160b170a3ade8b246843c9854af332475c047ba0
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

POM121L2 ROBO2 ROBO3 SVEP1 COL1A2

7.81e-061597653f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

CILP POM121L2 ROBO3 SVEP1 COL1A2

9.07e-061647652ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellLV-11._Adipocyte|World / Chamber and Cluster_Paper

GDPD5 MAMLD1 PPA1 ACSS2 SVEP1

9.62e-061667657e5852891714465c6228c9f955fd511ec79d0e02
ToppCellPND10-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLT3 POGLUT1 IL21R SCPEP1 NUDT17

1.05e-05169765a83e4078db91ecedee637b28b12ec38640fe45f9
ToppCellPND10-Immune-Immune_Myeloid-DC-maDC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLT3 POGLUT1 IL21R SCPEP1 NUDT17

1.05e-05169765f914aa8899fa170a09da31e5fad86de897ea789b
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NPR1 PTPRB EFCAB7 TAP2 NRP1

1.18e-0517376566488d01e03264fb193285470901c9c4182fbae8
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CILP IL21R SVEP1 ADGRD1 COL1A2

1.21e-051747659c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CILP IL21R SVEP1 ADGRD1 COL1A2

1.21e-05174765bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPEM2 PTPRB IL21R ITGA6 NRP1

1.31e-0517776557033ee0d49a4a50fc25328a4a44d4de2b35f505
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Activated_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

SLC6A12 FLT3 POGLUT1 CCNA1 PPA1

1.31e-05177765370aee11a6dc2c6f4366a13c3171f37bc5b32d65
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NEU4 SLC16A9 SLC13A1 FUT6 NRP1

1.39e-05179765d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VIL1 SLC16A9 SLC13A1 CUX1 NRP1

1.39e-0517976558ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MAGED1 POM121L2 ROBO2 SVEP1 COL1A2

1.39e-05179765b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCell10x5'-Lung-Myeloid_Dendritic-migDC|Lung / Manually curated celltypes from each tissue

NPR1 FLT3 POGLUT1 CCNA1 PPA1

1.42e-05180765e9e8992deb0beeee5548910e4616e7c990763d99
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2 NPR1 PTPRB MAMLD1 NRP1

1.46e-05181765a53f05c4c47465ee62e353716456bd09ab464b23
ToppCellClub-club-8|World / Class top

OPN4 CILP ACSS2 MUC5AC COL1A2

1.50e-051827658111d917e588008d947021460ddf8f1e7ae1337a
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2 NPR1 PTPRB MAMLD1 NRP1

1.54e-05183765709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2 NPR1 PTPRB MAMLD1 NRP1

1.54e-05183765dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP2 CILP MAMLD1 ADGRD1 COL1A2

1.58e-05184765d754c3de621429b220ae4ac426cdfc619e848462
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC61 SVEP1 ADGRD1 NRP1 COL1A2

1.62e-051857653cd0686a14e734a0f243070ab939adcb4c454478
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC61 SVEP1 ADGRD1 NRP1 COL1A2

1.62e-0518576500258f458cbf6d36449db95528a6b5038d731d2d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC61 SVEP1 ADGRD1 NRP1 COL1A2

1.62e-05185765a94694e226856bc5b168464f52d76004145717a5
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

NPR1 CILP ROBO3 ADGRD1 COL1A2

1.62e-05185765506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCell390C-Fibroblasts-Fibroblast-F|390C / Donor, Lineage, Cell class and subclass (all cells)

NPR1 CILP GRIN2D ADGRD1 COL1A2

1.62e-051857652c1f14f77faeee2acb388d997c5a27a7fef79be1
ToppCell390C-Fibroblasts-Fibroblast-F-|390C / Donor, Lineage, Cell class and subclass (all cells)

NPR1 CILP GRIN2D ADGRD1 COL1A2

1.62e-0518576537db8e0b1f59274227f6fc2362167eb44bd080ef
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMP2 NPR1 PTPRB FRMPD4 ITGA6

1.67e-0518676592092f11ecce22c14f244e42c499af0822977e6f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GDPD5 FLT3 ASTN2 GRIN2D ALK

1.71e-05187765d413fb4b1531b297af5012a392b88128510c2de8
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

SLC16A9 SLC13A1 ASTN2 FUT6 NRP1

1.71e-05187765738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

SLC16A9 SLC13A1 ASTN2 ACSS2 FUT6

1.71e-05187765acd305475f3609800af0d7bc68d83ef41228080b
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CILP ROBO3 SVEP1 ADGRD1 COL1A2

1.75e-05188765c32d023a69b6da79687ff8fa7485e7499db57046
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CILP ROBO3 SVEP1 ADGRD1 COL1A2

1.75e-051887651cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 CNTNAP2 ASTN2 GRIN2D ALK

1.85e-05190765d19bc44310c53726e2f5f6a2bd377bbbf1d1983f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAMLD1 SVEP1 ADGRD1 NRP1 COL1A2

1.85e-051907652306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP LRRC61 SVEP1 ADGRD1 COL1A2

1.85e-05190765d13fd234caa3fc69d8a59bc0060cdacdf716ee55
ToppCell21-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

BMP2 NPR1 PTPRB CLEC4M NRP1

1.85e-05190765bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GDPD5 FLT3 ASTN2 GRIN2D ALK

1.85e-05190765305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAMLD1 SVEP1 ADGRD1 NRP1 COL1A2

1.85e-051907651f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellBL-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC16A9 DTX4 FUT3 FUT6 MUC5AC

1.85e-05190765f2abe4bc28e934287e2dcd7b9399d5af78c5c8cf
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VIPR1 NPR1 PTPRB ITGA6 ROBO2

1.85e-05190765106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCell21-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

BMP2 NPR1 PTPRB CLEC4M NRP1

1.85e-0519076508437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAMLD1 SVEP1 ADGRD1 NRP1 COL1A2

1.89e-05191765a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CILP ROBO2 ASTN2 SVEP1 COL1A2

1.89e-05191765cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPHB6 FLT3 CNTNAP2 ASTN2 ALK

1.89e-05191765de54dab85db70f847de75b3b6d7667a0e13b9bfb
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

VIPR1 GDPD5 NPR1 PTPRB FRMPD4

1.89e-0519176554029b68fb78163c969890886ab0f8fb0dcf3c20
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAMLD1 SVEP1 ADGRD1 NRP1 COL1A2

1.94e-051927659093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAMLD1 SVEP1 ADGRD1 NRP1 COL1A2

1.94e-051927659ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR1 PTPRB SLC16A9 ITGA6 NRP1

1.94e-051927654bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 CNTNAP2 ROBO2 GRIN2D ALK

1.94e-0519276567d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPHB6 FLT3 CNTNAP2 ASTN2 ALK

1.94e-05192765dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 CNTNAP2 ASTN2 GRIN2D ALK

1.99e-051937654979862c0c16e6b4baa4c79894f1d237c861f5a5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAMLD1 SVEP1 ADGRD1 NRP1 COL1A2

1.99e-05193765f1199518c3626fd29bfce65070dd21a660671213
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 LRRC61 SVEP1 ADGRD1 COL1A2

1.99e-05193765f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 LRRC61 SVEP1 ADGRD1 COL1A2

1.99e-0519376585faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GDPD5 FLT3 ASTN2 GRIN2D ALK

1.99e-05193765c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CNTNAP2 ROBO2 SVEP1 NRP1 COL1A2

1.99e-05193765acad568621ed677031797b8c2e34dafea798d681
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPHB6 FLT3 CNTNAP2 ROBO2 ASTN2

1.99e-05193765658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 CNTNAP2 ASTN2 GRIN2D ALK

1.99e-051937655581a5ebcd21a2a8062ccfb917f088ec67a10a9c
ToppCellfacs-MAT-Fat-3m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 LRRC61 SVEP1 ADGRD1 COL1A2

1.99e-05193765110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCellGoblet|World / shred by cell class for turbinate

MAGED1 SLC16A9 FUT3 FUT6 MUC5AC

2.04e-0519476503b62e7cff5e7a6e7bd7d9dda273c74bf9c1f42e
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VIPR1 GDPD5 NPR1 PTPRB ITGA6

2.04e-05194765efd5efed060edb7f24d59600981bb60ec28ac2ef
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR1 PTPRB SLC16A9 ITGA6 NRP1

2.04e-05194765f159ef8541d75a4e98468947f231bb463bec922c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 CNTNAP2 ROBO2 ASTN2 ALK

2.04e-05194765e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 CILP LRRC61 SVEP1 COL1A2

2.09e-0519576569a29d03e664b72f32d41876510c62345c3aed31
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GDPD5 NPR1 PTPRB ITGA6 NRP1

2.09e-05195765cc3d6f98d310e8840ff497d7258c5ccf54e6c624
ToppCellfacs-GAT-Fat-3m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 CILP LRRC61 SVEP1 COL1A2

2.09e-051957651cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 CILP LRRC61 SVEP1 COL1A2

2.09e-051957659cef6f18664518060af7c192310dddce6d70345a
ToppCellNS-moderate-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAGED1 SLC16A9 DTX4 FUT3 FUT6

2.14e-0519676570384c1da9baed843f414cfd1403ddd586a2db07
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 CNTNAP2 ROBO2 GRIN2D ALK

2.14e-051967657af6c5147ac859353504d19727dbe24f63a29dd4
ToppCellControl-Stromal-Fibroblast|World / Disease state, Lineage and Cell class

NPR1 CILP SVEP1 ADGRD1 COL1A2

2.14e-051967651ec7a4daa51b3156db97e1fd6cb925ad311bb4b5
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VIPR1 GDPD5 NPR1 PTPRB ITGA6

2.14e-0519676581278e696d823744267d6315c4d42799c4ea0b2c
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VIPR1 GDPD5 NPR1 PTPRB ITGA6

2.20e-05197765a7922f65a8af4a773e4ce80114e4d895a594fa2f
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

VIPR1 GDPD5 NPR1 PTPRB ITGA6

2.20e-0519776521a1080e1db3a64f3eccc7aed2b3189332d31038
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAGED1 CNTNAP2 ROBO2 SVEP1 COL1A2

2.20e-051977659af431323da6d099459b7360af40e5df998cffbd
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

VIPR1 GDPD5 NPR1 PTPRB ITGA6

2.20e-0519776588859b7b24b36afab4a684fd7abf0e0f8e5b525c
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAGED1 DTX4 FUT3 FUT6 MUC5AC

2.20e-05197765a72047b7428c0d4aaf016c1ac23dc30919260fd8
DrugSulfamethoxazole [723-46-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A

VIPR1 NPR1 TNRC6B LRRC61 FUT3 MAST2 MUC5AC ALK

2.69e-071967582296_UP
DrugBromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A

BMP2 NPR1 CILP CNTNAP2 FUT6 MUC5AC ALK NRP1

2.91e-071987586037_UP
DrugAC1MPID6

FUT3 FUT5 FUT6

6.82e-076753CID003411618
Druglacto-N-tetraose

NEU4 FUT3 FUT5 FUT6

3.64e-0632754CID000440993
Drug(-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A

GDPD5 ROBO3 FUT6 C11orf16 MUC5AC SVEP1 COL1A2

3.81e-061967573571_UP
DrugAC1MQWF5

FUT3 FUT5 FUT6

4.05e-0610753CID003458642
DrugPrilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A

NPR1 MFSD6 FUT3 MUC5AC ALK SVEP1 SLC5A3

4.21e-061997574749_UP
Druglacto-N-neotetraose

NEU4 FUT3 FUT5 FUT6

1.60e-0546754CID000121853
DrugAC1MPID3

FUT3 FUT5 FUT6

3.20e-0519753CID003411617
DrugHexestrol [84-16-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A

VIL1 FLT3 AVPR1B FUT6 ALK SLC5A3

4.01e-051917566077_UP
DrugBetamethasone [378-44-9]; Up 200; 10.2uM; MCF7; HT_HG-U133A

EPHB6 GDPD5 FLT3 ITGA6 LRRC61 SVEP1

4.38e-051947565328_UP
DrugDeoxycorticosterone [64-85-7]; Up 200; 12.2uM; HL60; HT_HG-U133A

VIL1 BMP10 CNTNAP2 CLEC4M FUT6 C11orf16

4.50e-051957563099_UP
Drugselenate

SLC13A1 FUT3 FUT5 FUT6

4.60e-0560754CID000001089
DrugBetonicine [515-25-3]; Down 200; 25.2uM; HL60; HT_HG-U133A

EPHB6 BTN2A2 ABCA2 FUT6 ALK CEP170B

4.63e-051967562207_DN
DrugFlumequine [42835-25-6]; Up 200; 15.4uM; MCF7; HT_HG-U133A

EPHB6 ABCA2 PTPRB AVPR1B CNTNAP2 FUT6

4.77e-051977562276_UP
DrugTrimetazidine dihydrochloride [13171-25-0]; Up 200; 11.8uM; PC3; HT_HG-U133A

NPR1 ABCA2 PTPRB FUT6 C11orf16 ALK

4.77e-051977565060_UP
DrugOrphenadrine hydrochloride [341-69-5]; Up 200; 13uM; PC3; HT_HG-U133A

NPR1 ABCA2 SLC12A4 IL21R LRRC61 C11orf16

4.77e-051977563801_UP
Drug(S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; HL60; HT_HG-U133A

BTN2A2 FRMPD4 IL21R CNTNAP2 FUT6 C11orf16

4.90e-051987563067_UP
DrugSulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A

DIXDC1 CLEC4M FUT3 SVEP1 NRP1 SLC5A3

4.90e-051987565446_UP
DrugMeclocycline sulfosalicylate [73816-42-9]; Up 200; 5.8uM; PC3; HT_HG-U133A

BMP2 PTPRB CNTNAP2 TNRC6B MAST2 ALK

4.90e-051987566637_UP
DrugDoxylamine succinate [562-10-7]; Up 200; 10.2uM; PC3; HT_HG-U133A

NPR1 SLC13A1 IL21R CNTNAP2 ALK COL1A2

4.90e-051987564235_UP
DrugDrofenine hydrochloride [548-66-3]; Up 200; 11.4uM; HL60; HT_HG-U133A

ABCA2 SLC12A4 CILP MAMLD1 ITGA6 SLC5A3

4.90e-051987562714_UP
DrugMycophenolic acid [24280-93-1]; Up 200; 12.4uM; PC3; HT_HG-U133A

ABCA2 CNTNAP2 FUT6 ALK NRP1 SLC5A3

4.90e-051987564019_UP
DrugLevamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; MCF7; HT_HG-U133A

NPR1 ABCA2 MFSD6 CNTNAP2 FUT5 FUT6

5.04e-051997562257_UP
DrugDeptropine citrate [2169-75-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A

CNTNAP2 POM121L2 FUT6 MUC5AC SVEP1 COL1A2

5.04e-051997565543_UP
DrugPhenethicillin potassium salt [132-93-4]; Up 200; 10uM; MCF7; HT_HG-U133A

BTN2A2 ABCA2 MFSD6 POM121L2 CLEC4M ALK

5.04e-051997566105_UP
DrugKetoconazole [65277-42-1]; Up 200; 7.6uM; MCF7; HT_HG-U133A

EPHB6 ABCA2 C11orf16 ALK SVEP1 NRP1

5.04e-051997562640_UP
DrugFoliosidine [2520-38-9]; Up 200; 13uM; MCF7; HT_HG-U133A

BTN2A2 PTPRB BMP10 IL21R FUT6 ALK

5.19e-052007566057_UP
DrugTrimethadione [127-48-0]; Up 200; 28uM; PC3; HT_HG-U133A

SLC13A1 CILP POM121L2 CLEC4M C11orf16 NRP1

5.19e-052007564086_UP
DrugHydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; PC3; HT_HG-U133A

ABCA2 MFSD6 LRRC61 FUT3 FUT6 ALK

5.19e-052007564489_DN
DrugAmidopyrine [58-15-1]; Up 200; 17.2uM; PC3; HT_HG-U133A

VIPR1 NPR1 SLC12A4 BMP10 ASTN2 ALK

5.19e-052007564481_UP
Drug(2S,3R,4S,5S,6R)-2-benzyl-6-(hydroxymethyl)oxane-3,4,5-triol

FUT3 FUT5 FUT6

5.80e-0523753CID010332525
DrugsLex

NEU4 FUT3 FUT5 FUT6

9.43e-0572754CID004564901
DrugSNAC

EPHB6 NPR1 TAP2

1.18e-0429753CID000158789
DrugsLea

FUT3 FUT5 FUT6 MUC5AC

1.29e-0478754CID000643993
Drug2'-fucosyllactose

FUT3 FUT5 FUT6

1.31e-0430753CID000170484
Diseasealpha-(1;3)-fucosyltransferase 5 measurement

FUT3 FUT5 FUT6

6.05e-084743EFO_0021979
Diseasegalactoside 3(4)-L-fucosyltransferase measurement

FUT3 FUT5 FUT6

5.26e-077743EFO_0021853
Diseasealpha-(1,3)-fucosyltransferase 5 measurement

FUT3 FUT5 FUT6

5.26e-077743EFO_0020136
Diseaseserum carcinoembryonic antigen measurement

FUT3 FUT5 FUT6

1.67e-0520743EFO_0005760
Diseasetriglyceride change measurement, high density lipoprotein cholesterol measurement

CNTNAP2 ROBO2

1.86e-053742EFO_0004612, EFO_0007681
Diseasecancer antigen 19.9 measurement

FUT3 FUT6

3.71e-054742EFO_0010584
Diseasepolyp of gallbladder

FUT3 FUT6

3.71e-054742MONDO_0021416
Diseasedesmoglein-2 measurement

FUT3 FUT6

6.17e-055742EFO_0020322
Diseaselevel of V-set and immunoglobulin domain-containing protein 2 in blood serum

FUT3 FUT6

6.17e-055742OBA_2044774
Diseaselactoperoxidase measurement

FUT3 FUT6

9.25e-056742EFO_0020525
Diseaselithostathine-1-alpha measurement

FUT3 FUT6

1.29e-047742EFO_0801083
Diseasemyoclonic-atonic epilepsy (implicated_via_orthology)

ROBO2 ROBO3

1.29e-047742DOID:0060475 (implicated_via_orthology)
Diseasegallstones

TNRC6B FUT3 FUT6 MUC5AC

1.60e-04108744EFO_0004210
Diseasecandidiasis (implicated_via_orthology)

FUT3 FUT5 FUT6

1.86e-0444743DOID:1508 (implicated_via_orthology)
Diseaseidiopathic pulmonary fibrosis

FUT3 FUT6 MUC5AC

4.02e-0457743EFO_0000768
Diseaserotator cuff tear, shoulder impingement syndrome

FRMPD4 ASTN2

4.03e-0412742EFO_1001178, EFO_1001250
DiseaseAutistic Disorder

CNTNAP2 ROBO2 ASTN2 DIXDC1 ROBO3

5.10e-04261745C0004352
DiseaseHeadache

BTN2A2 ASTN2 CUX1

5.65e-0464743HP_0002315
Diseasecancer biomarker measurement

FUT3 FUT6

6.38e-0415742EFO_0005127
Diseaseautism spectrum disorder (is_implicated_in)

AVPR1B CNTNAP2

7.28e-0416742DOID:0060041 (is_implicated_in)
Diseasegalectin-3 measurement

FUT3 FUT6

7.28e-0416742EFO_0008137
Diseasecircadian rhythm

ANKIB1 TNRC6B ROBO2 COL1A2

7.64e-04163744EFO_0004354
Diseaseepilepsy (implicated_via_orthology)

SLC12A4 SLC13A1 ITGA6 GRIN2D

7.64e-04163744DOID:1826 (implicated_via_orthology)
Diseasenucleotide measurement

VIPR1 PTPRB ALK

8.30e-0473743EFO_0010513
DiseaseUterine leiomyoma, estrogen-receptor positive breast cancer

TNRC6B ASTN2

9.25e-0418742EFO_1000649, HP_0000131
DiseaseBipolar Disorder

TRPC7 AVPR1B CNTNAP2 ASTN2 DIXDC1 SLC5A3

1.27e-03477746C0005586
DiseaseN-glycan measurement

FUT3 FUT6

1.39e-0322742EFO_0004999
Diseasee-selectin measurement

FUT3 FUT6

1.39e-0322742EFO_0004575
Diseasecholelithiasis

TNRC6B FUT3 FUT6

1.43e-0388743EFO_0004799
Diseaseepiandrosterone sulfate measurement

TRIM4 ALK

1.79e-0325742EFO_0021120
Diseasesusceptibility to pneumonia measurement

FUT5 MUC5AC TAP2

1.89e-0397743EFO_0008410
Diseaseosteoarthritis (is_implicated_in)

BMP2 CILP

2.25e-0328742DOID:8398 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
WISGTYPSPQSYDSW

FAM227A

281

F5H4B4
VWGSPYSPPREDWSV

CDX4

71

O14627
LWSYPDLLPTFTTWP

EIF2D

86

P41214
WEASFSPPGPYWTHV

ADGRD1

156

Q6QNK2
QGPSSSEYWKEWPSA

CUX1

871

P39880
DWRPGSPGTYLETSW

DIXDC1

266

Q155Q3
AGGTWDWEYLGFASP

ANKIB1

746

Q9P2G1
EGWGPEEPLPYSWAF

CFC1B

66

P0CG36
GTVGEPINPEAWLWY

ACSS2

436

Q9NR19
TSYPWSWARVGPAVE

NPR1

46

P16066
SYRTPLYGQPSWWGE

CEP170B

161

Q9Y4F5
LYGQPSWWGEDDGST

CEP170B

166

Q9Y4F5
YDPSSAPGKGVVWEW

DTX4

81

Q9Y2E6
SDVGWNDWIVAPPGY

BMP2

306

P12643
RSDWGQSEGPWPYTT

ASTN2

551

O75129
FWEGGPAVWPIYPTG

POGLUT1

166

Q8NBL1
GPPIVGWFYDWTQTY

SLC16A9

446

Q7RTY1
VSWSPPAGDWEQYRI

PTPRB

396

P23467
GDFGDPWSRIPFTFW

MAGED1

721

Q9Y5V3
FSWVPLGLWESAYPP

NUDT17

156

P0C025
LGLWESAYPPRLSWG

NUDT17

161

P0C025
EPGYWESWPSRSSSI

LRRC61

201

Q9BV99
GYWSDWPVPILVTTA

GDPD5

81

Q8WTR4
TWTEWIDGSYPAPGI

MUC5AC

1956

P98088
TWTTWFDVDFPSPGP

MUC5AC

2121

P98088
FPSKTVAQYSGVPWW

ITGA6

1041

P23229
PAWGVSSSPWVTFVY

MFSD6

686

Q6ZSS7
LDPRSWTEPWVIYEG

NEU4

401

Q8WWR8
WTEPWVIYEGPSGYS

NEU4

406

Q8WWR8
PENGWTPGEDSYREW

NRP1

311

O14786
WSLPPFFGWSAYVPE

OPN4

201

Q9UHM6
SCFSDGYPLPSWTWK

FLT3

451

P36888
PEWSSGYYWIDPNQG

COL1A2

1171

P08123
GWDSWIIAPPGYEAY

BMP10

336

O95393
WTGELGPGIYWLIPS

EFCAB7

356

A8K855
SGTWGLSQVPPYGWE

FRMPD4

26

Q14CM0
PWPWGITKDSGFAFT

CPAMD8

676

Q8IZJ3
TFPSACPYWIWGGKV

CYP4A22

81

Q5TCH4
PGSFIGGWGEEYLSW

CCNA1

11

P78396
PWYFPLQKSYWLGSG

ABCA2

926

Q9BZC7
DSDIFTPYGWLEPWS

FUT6

161

P51993
YSTSEAAPWGSWDPK

MAMLD1

731

Q13495
YPFVTWLSGYPLWGG

MS4A18

181

Q3C1V0
PSYEDPSQGWLWESE

MAST2

1716

Q6P0Q8
IWNYGAIPQTWEDPG

PPA1

91

Q15181
LNTPDGSPYTWWVGK

CNTNAP2

696

Q9UHC6
PGSSYQGTWSEWSDP

IL21R

206

Q9HBE5
YPWEWGEKGISTARP

HERVK_113

311

Q902F9
WYLGYPGDQWSSGFP

CCDC144A

36

A2RUR9
YLESAPGWPVGQEEW

C1orf127

566

Q8N9H9
WLECISGGWYPEPLT

BTN2A2

166

Q8WVV5
SGGWYPEPLTVWRDP

BTN2A2

171

Q8WVV5
WFSRDPGFVPGWSAL

SLC13A1

361

Q9BZW2
SDSDIFTPYGWLEPW

FUT3

161

P21217
FTPYGWLEPWSGQPA

FUT3

166

P21217
SDIFTPYGWLEPWSG

FUT5

176

Q11128
SWISPVDSVLSWGPY

SCPEP1

201

Q9HB40
IGWLTYPPGGWDEVS

EPHB6

46

O15197
YPPWGYSIGWFLALS

SLC6A12

531

P48065
WPGFILGQTPASVWY

SLC5A3

261

P53794
SAPWSWLLVGYGAAG

TAP2

96

Q03519
RYWGTPIPLWVSDDF

IARS1

461

P41252
YEDGVWKPTYTTEWP

SVEP1

771

Q4LDE5
NSPLGPLPSDWWESY

POM121L2

86

Q96KW2
VVLGWPYGWRQSEDP

SLC12A4

791

Q9UP95
SLWNPTYGSWFTEKP

ALK

1501

Q9UM73
ESPGEWTTWFNIDYP

CILP

51

O75339
WVDGSPLSPSFQRYW

CLEC4M

341

Q9H2X3
WDGAAPPWDLSFTYP

C11orf16

26

Q9NQ32
GHEPPTFTGWFLAWD

VIL1

701

P09327
PTLVSGDPWYPWYNW

MRPS18B

191

Q9Y676
WGYILIGWGVPSTFT

VIPR1

256

P32241
GFPWGPRAYLTWTTL

AVPR1B

191

P47901
SWVPVGHSPYPSVGW

SPEM2

291

Q0P670
SGDLGPWSQYAPPEW

ROBO3

1041

Q96MS0
PWSQYAPPEWSQGDS

ROBO3

1046

Q96MS0
AGDPSYPWLADSWPA

ROBO2

916

Q9HCK4
GYPNAEFKSWWPATS

MARS2

291

Q96GW9
ALGSYPIWWSLAVGP

WNT3A

16

P56704
WSAAGYWPLIGFPGT

TRIM4

421

Q9C037
PRQDWTGSTPAYGYW

SIGLEC10

46

Q96LC7
YPWILFWCSGSPFPE

XK

251

P51811
SLWGPPNYSSSLWGV

TNRC6B

1791

Q9UPQ9
WWPSDPQIISEGLYA

TRPC7

531

Q9HCX4
LGGLEPWWFADFPYP

GRIN2D

1126

O15399