Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZBTB7A SLC2A4RG FOXQ1 NFATC4 PATZ1 GLI2 ESR1 TBX20 ZNF865 TCFL5 TCF7L1 KDM1A TWIST1 FOXL1 OVOL2	1.46e-04	1244	82	15	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZBTB7A SLC2A4RG FOXQ1 NFATC4 PATZ1 GLI2 ESR1 TBX20 ZNF865 TCFL5 TCF7L1 KDM1A TWIST1 FOXL1 OVOL2	1.85e-04	1271	82	15	GO:0000987
GeneOntologyMolecularFunction	promoter-specific chromatin binding	TRIM28 GLI2 ESR1 KDM1A	3.79e-04	83	82	4	GO:1990841
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	ZBTB7A FOXQ1 NFATC4 PATZ1 TCFL5 TWIST1 OVOL2	3.86e-04	326	82	7	GO:0001217
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZBTB7A SLC2A4RG FOXQ1 NFATC4 PATZ1 GLI2 ESR1 TBX20 ZNF865 TCFL5 TCF7L1 KDM1A TWIST1 FOXL1 OVOL2	7.97e-04	1459	82	15	GO:0000977
GeneOntologyMolecularFunction	chromatin binding	PRDM8 TRIM28 PATZ1 GLI2 ESR1 SMARCD1 NUP62 TCF7L1 KDM1A OVOL2	8.76e-04	739	82	10	GO:0003682
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	ZBTB7A FOXQ1 NFATC4 TRIM28 PATZ1 TRO GLI2 ESR1 BCORL1 MAGEB17 TBX20 TCFL5 KDM1A TWIST1 OVOL2	1.76e-05	1053	83	15	GO:0000122
GeneOntologyBiologicalProcess	neuron projection morphogenesis	SEMA6C PRDM8 EFNB1 CELSR2 ATXN2 NFATC4 GLI2 MYPN GAS1 TMEM108 ZSWIM6 LGR6 KDM1A	1.80e-05	802	83	13	GO:0048812
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	SEMA6C PRDM8 EFNB1 CELSR2 ATXN2 NFATC4 GLI2 MYPN GAS1 TMEM108 ZSWIM6 LGR6 KDM1A	2.24e-05	819	83	13	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	SEMA6C PRDM8 EFNB1 CELSR2 ATXN2 NFATC4 GLI2 MYPN GAS1 TMEM108 ZSWIM6 LGR6 KDM1A	2.45e-05	826	83	13	GO:0048858
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	ZBTB7A PRDM8 FOXQ1 NFATC4 TRIM28 PATZ1 TRO GLI2 ESR1 BCORL1 MAGEB17 TBX20 TCFL5 TCF7L1 KDM1A TWIST1 OVOL2	3.47e-05	1399	83	17	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	ZBTB7A PRDM8 FOXQ1 NFATC4 TRIM28 PATZ1 TRO GLI2 ESR1 BCORL1 MAGEB17 TBX20 TCFL5 TCF7L1 KDM1A TWIST1 OVOL2	3.94e-05	1413	83	17	GO:1902679
GeneOntologyBiologicalProcess	tissue morphogenesis	FOXQ1 NFATC4 DSPP TRIM28 GLI2 ESR1 CC2D2A TBX20 TCF7L1 TWIST1 FOXL1 OVOL2	4.44e-05	750	83	12	GO:0048729
GeneOntologyBiologicalProcess	neural crest cell migration	SEMA6C EFNB1 TWIST1 OVOL2	1.14e-04	62	83	4	GO:0001755
GeneOntologyBiologicalProcess	mesenchymal cell migration	SEMA6C EFNB1 TWIST1 OVOL2	1.29e-04	64	83	4	GO:0090497
GeneOntologyBiologicalProcess	neural tube development	GLI2 GAS1 CC2D2A AMBRA1 TWIST1 OVOL2	1.65e-04	202	83	6	GO:0021915
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	FOXQ1 NFATC4 DSPP TRIM28 GLI2 ESR1 CC2D2A TBX20 TWIST1 OVOL2	1.87e-04	619	83	10	GO:0002009
GeneOntologyBiologicalProcess	mesenchymal cell differentiation	SEMA6C EFNB1 TRIM28 TBX20 KDM1A TWIST1 OVOL2	1.91e-04	296	83	7	GO:0048762
GeneOntologyBiologicalProcess	negative regulation of miRNA transcription	NFATC4 ESR1 TWIST1	2.60e-04	31	83	3	GO:1902894
GeneOntologyBiologicalProcess	cell morphogenesis	SEMA6C PRDM8 EFNB1 CELSR2 ATXN2 NFATC4 GLI2 MYPN GAS1 TMEM108 FGD5 ZSWIM6 LGR6 KDM1A	2.73e-04	1194	83	14	GO:0000902
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	NFATC4 DSPP GLI2 ESR1 CC2D2A TBX20 TWIST1 OVOL2	2.92e-04	421	83	8	GO:0060562
GeneOntologyBiologicalProcess	negative regulation of intracellular signal transduction	ZBTB7A UBQLN1 ESR1 DUSP7 RPS6KA6 PHLPP1 NUP62 TBX20 KDM1A TWIST1 OVOL2	3.35e-04	795	83	11	GO:1902532
GeneOntologyBiologicalProcess	negative regulation of miRNA metabolic process	NFATC4 ESR1 TWIST1	3.44e-04	34	83	3	GO:2000629
GeneOntologyBiologicalProcess	odontogenesis	DSPP GLI2 GAS1 MUC19 COL1A2	3.61e-04	151	83	5	GO:0042476
GeneOntologyCellularComponent	DNA-dependent protein kinase complex	ZBTB7A UVRAG	1.66e-04	5	86	2	GO:0070418
GeneOntologyCellularComponent	nuclear pore central transport channel	NUP62 NUP54	3.47e-04	7	86	2	GO:0044613
GeneOntologyCellularComponent	Cul4-RING E3 ubiquitin ligase complex	DCAF8L1 DCAF8L2 AMBRA1	5.11e-04	38	86	3	GO:0080008
HumanPheno	Structural abnormalities in the basal ganglia	LONP1 NUP62 NUP54	1.01e-05	8	30	3	HP:0006952
HumanPheno	Basal ganglia cysts	LONP1 NUP62 NUP54	1.01e-05	8	30	3	HP:0006799
HumanPheno	Midline defect of the nose	LONP1 EFNB1 FRMPD4 ZSWIM6	2.41e-05	30	30	4	HP:0004122
HumanPheno	Basal ganglia gliosis	LONP1 NUP62 NUP54	2.95e-05	11	30	3	HP:0006999
HumanPheno	Abnormal nasal tip morphology	LONP1 EFNB1 FRMPD4 GLI2 SMARCD1 ZSWIM6 KDM1A MADD TWIST1 COL1A2	4.21e-05	386	30	10	HP:0000436
Domain	NUT	NUTM2F NUTM2G	1.93e-04	5	83	2	IPR024310
Domain	NUT_N	NUTM2F NUTM2G	1.93e-04	5	83	2	IPR024309
Domain	NUT	NUTM2F NUTM2G	1.93e-04	5	83	2	PF12881
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	IRS4 UBQLN1 ATXN2 NFATC4 TRO GLI2 ESR1 UBR4 LMTK3 UVRAG SH3D21	1.40e-08	430	89	11	35044719
Pubmed	Human transcription factor protein interaction networks.	ZBTB7A LONP1 IRS4 FOXQ1 ATXN2 NFATC4 GLI2 ESR1 UBR4 BCORL1 SLC5A9 SMARCD1 R3HDM2 NUP62 ANKHD1 KDM1A NUP54 FOXL1	1.90e-08	1429	89	18	35140242
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	ZBTB7A LONP1 CDV3 COL16A1 UBR4 DUSP7 BCORL1 FGD5 NUP62 MADD COL1A2	1.53e-06	689	89	11	36543142
Pubmed	Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer.	ESR1 LMTK3	6.48e-06	2	89	2	21602804
Pubmed	TRIM8 inhibits breast cancer proliferation by regulating estrogen signaling.	ESR1 TRIM8	6.48e-06	2	89	2	33163282
Pubmed	TCF7L1 regulates colorectal cancer cell migration by repressing GAS1 expression.	GAS1 TCF7L1	6.48e-06	2	89	2	38816533
Pubmed	Role of genetic background in determining phenotypic severity throughout postnatal development and at peak bone mass in Col1a2 deficient mice (oim).	NFATC4 COL1A2	6.48e-06	2	89	2	18313376
Pubmed	RSK4 inhibits breast cancer cell proliferation and invasion in vitro, and is correlated with estrogen receptor upregulation in breast cancer.	ESR1 RPS6KA6	6.48e-06	2	89	2	31545499
Pubmed	Tripartite motif containing 28 (TRIM28) promotes breast cancer metastasis by stabilizing TWIST1 protein.	TRIM28 TWIST1	6.48e-06	2	89	2	27412325
Pubmed	Ovol2 gene inhibits the Epithelial-to-Mesenchymal Transition in lung adenocarcinoma by transcriptionally repressing Twist1.	TWIST1 OVOL2	6.48e-06	2	89	2	27884772
Pubmed	Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex.	NUP62 NUP54	6.48e-06	2	89	2	8589458
Pubmed	Stimulatory cross-talk between NFAT3 and estrogen receptor in breast cancer cells.	NFATC4 ESR1	6.48e-06	2	89	2	16219765
Pubmed	ZBTB7A governs estrogen receptor alpha expression in breast cancer.	ZBTB7A ESR1	6.48e-06	2	89	2	30265334
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ZBTB7A FOXQ1 NFATC4 GLI2 ESR1 TBX20 TCFL5 TCF7L1 OVOL2	1.10e-05	544	89	9	28473536
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	NFATC4 TRIM28 GLI2 ESR1 TRIM8 SMARCD1 TACC2 TCF7L1 TWIST1 FOXL1	1.39e-05	709	89	10	22988430
Pubmed	Expression and significance of Twist, estrogen receptor, and E-cadherin in human breast cancer cells and tissues.	ESR1 TWIST1	1.94e-05	3	89	2	28901319
Pubmed	Interactions and three-dimensional localization of a group of nuclear pore complex proteins.	NUP62 NUP54	1.94e-05	3	89	2	8045926
Pubmed	LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP.	ESR1 KDM1A	1.94e-05	3	89	2	27325688
Pubmed	TWIST1-EP300 Expedites Gastric Cancer Cell Resistance to Apatinib by Activating the Expression of COL1A2.	TWIST1 COL1A2	1.94e-05	3	89	2	35242497
Pubmed	Contribution of DNA methylation to the expression of FCGRT in human liver and myocardium.	ZBTB7A FCGRT	1.94e-05	3	89	2	31209240
Pubmed	Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors.	ESR1 KDM1A	1.94e-05	3	89	2	17289570
Pubmed	Twist activates miR-22 to suppress estrogen receptor alpha in breast cancer.	ESR1 TWIST1	1.94e-05	3	89	2	33582945
Pubmed	A census of human transcription factors: function, expression and evolution.	ZBTB7A FOXQ1 NFATC4 PATZ1 GLI2 ESR1 TBX20 TCFL5 TCF7L1 TWIST1 FOXL1	2.07e-05	908	89	11	19274049
Pubmed	The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function.	GLI2 TBX20	3.87e-05	4	89	2	23988578
Pubmed	Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen.	ESR1 TCF7L1	3.87e-05	4	89	2	18202148
Pubmed	Negative regulation of ERα by a novel protein CAC1 through association with histone demethylase LSD1.	ESR1 KDM1A	3.87e-05	4	89	2	23178685
Pubmed	Twist contributes to hormone resistance in breast cancer by downregulating estrogen receptor-α.	ESR1 TWIST1	3.87e-05	4	89	2	22056872
Pubmed	Endothelial Cyp26b1 restrains murine heart valve growth during development.	NFATC4 FCGRT TBX20 TWIST1 COL1A2	6.42e-05	163	89	5	35364055
Pubmed	TWIST represses estrogen receptor-alpha expression by recruiting the NuRD protein complex in breast cancer cells.	ESR1 TWIST1	6.44e-05	5	89	2	22457607
Pubmed	TIF1gamma, a novel member of the transcriptional intermediary factor 1 family.	TRIM28 ESR1	6.44e-05	5	89	2	10022127
Pubmed	The nuclear pore complex: from molecular architecture to functional dynamics.	NUP62 NUP54	6.44e-05	5	89	2	10395558
Pubmed	Genomic analysis distinguishes phases of early development of the mouse atrio-ventricular canal.	TBX20 TWIST1	6.44e-05	5	89	2	19952280
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXQ1 NFATC4 PATZ1 TRO UBR4 CHSY3 ANKHD1 KDM1A TWIST1 FOXL1	6.88e-05	857	89	10	25609649
Pubmed	Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.	TRIM28 GLI2 ANKHD1 TCF7L1	9.03e-05	91	89	4	21194568
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	IRS4 TRIM28 PATZ1 SMARCD1 NUP62 KDM1A NUP54	9.17e-05	411	89	7	35182466
Pubmed	Foxl1-deficient mice exhibit aberrant epithelial cell positioning resulting from dysregulated EphB/EphrinB expression in the small intestine.	EFNB1 FOXL1	9.65e-05	6	89	2	16469829
Pubmed	Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation.	ESR1 COL1A2	9.65e-05	6	89	2	31943281
Pubmed	Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import.	NUP62 NUP54	9.65e-05	6	89	2	11266456
Pubmed	Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice.	SEMA6C TBX20 TWIST1	9.99e-05	35	89	3	28172500
Pubmed	FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice.	ESR1 TWIST1 COL1A2	1.28e-04	38	89	3	26134413
Pubmed	Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins.	NUP62 NUP54	1.35e-04	7	89	2	8707840
Pubmed	FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine.	GLI2 FOXL1	1.35e-04	7	89	2	19049965
Pubmed	Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line.	GLI2 GAS1	1.35e-04	7	89	2	28799057
Pubmed	Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction.	SYN1 MADD	1.35e-04	7	89	2	11359932
Pubmed	PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity.	ESR1 KDM1A	1.35e-04	7	89	2	20448663
Pubmed	Prevalence and complications of single-gene and chromosomal disorders in craniosynostosis.	EFNB1 TWIST1	1.35e-04	7	89	2	20643727
Pubmed	Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland.	GLI2 TCF7L1	1.35e-04	7	89	2	16678815
Pubmed	Transit-amplifying cells orchestrate stem cell activity and tissue regeneration.	GLI2 GAS1	1.35e-04	7	89	2	24813615
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	FRMPD4 ARHGEF10 MADD PDZD2	1.52e-04	104	89	4	9205841
Pubmed	Identification of genes expressed preferentially in the developing peripheral margin of the optic cup.	IRS4 GAS1 TCF7L1	1.73e-04	42	89	3	19449303
Pubmed	CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.	LONP1 IRS4 AMBRA1 ANKHD1	1.75e-04	108	89	4	30166453
Pubmed	Genetic predisposition for femoral neck stress fractures in military conscripts.	ESR1 COL1A2	1.79e-04	8	89	2	20961463
Pubmed	Spatiotemporal expression of sonic hedgehog signalling molecules in the embryonic mesencephalic dopaminergic neurons.	GLI2 GAS1	1.79e-04	8	89	2	34767969
Pubmed	Activation of RIG-I-Mediated Antiviral Signaling Triggers Autophagy Through the MAVS-TRAF6-Beclin-1 Signaling Axis.	AMBRA1 UVRAG	1.79e-04	8	89	2	30258449
Pubmed	Different classes of coactivators recognize distinct but overlapping binding sites on the estrogen receptor ligand binding domain.	TRIM28 ESR1	1.79e-04	8	89	2	9774463
Pubmed	TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation.	TCF7L1 TWIST1	1.79e-04	8	89	2	32179550
Pubmed	Gene polymorphisms, bone mineral density and bone mineral content in young children: the Iowa Bone Development Study.	ESR1 COL1A2	1.79e-04	8	89	2	12879219
Pubmed	Systematic Protein-Protein Interaction Analysis Reveals Intersubcomplex Contacts in the Nuclear Pore Complex.	NUP62 NUP54	1.79e-04	8	89	2	27194810
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	IRS4 UBQLN1 RNF185 UBR4 SYN1 SMARCD1	1.83e-04	322	89	6	26514267
Pubmed	SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms.	IRS4 UBQLN1 AMBRA1 KDM1A	1.88e-04	110	89	4	28883622
Pubmed	Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells.	KDM1A OVOL2	2.30e-04	9	89	2	24448552
Pubmed	Distinct expression patterns of Hedgehog signaling components in mouse gustatory system during postnatal tongue development and adult homeostasis.	GLI2 GAS1	2.30e-04	9	89	2	38848388
Pubmed	New Insights into Development of Female Reproductive Tract-Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development.	GLI2 ESR1	2.30e-04	9	89	2	33530552
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	EFNB1 SYN1 CBARP LMTK3 MTCH1 MADD	2.74e-04	347	89	6	17114649
Pubmed	Ephrin-B2 forward signaling regulates somite patterning and neural crest cell development.	EFNB1 TWIST1	2.88e-04	10	89	2	17223098
Pubmed	WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1).	IRS4 PHLPP1	2.88e-04	10	89	2	24145035
Pubmed	Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos.	TBX20 COL1A2	2.88e-04	10	89	2	15162503
Pubmed	Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex.	AMBRA1 UVRAG	2.88e-04	10	89	2	22493499
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	PATZ1 UBR4 RPS6KA6 LMTK3 ANKHD1	3.40e-04	233	89	5	37704626
Pubmed	Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse.	TBX20 TWIST1	3.51e-04	11	89	2	22815831
Pubmed	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.	ESR1 SMARCD1	3.51e-04	11	89	2	12917342
Pubmed	Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium.	ESR1 FOXL1	3.51e-04	11	89	2	24430505
Pubmed	New tools for studying microglia in the mouse and human CNS.	SELPLG FCRL2	3.51e-04	11	89	2	26884166
Pubmed	Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.	ATXN2 UBR4 AMBRA1	4.07e-04	56	89	3	27103069
Pubmed	Genome-wide association study of conduct disorder symptomatology.	SELPLG CC2D2A	4.20e-04	12	89	2	20585324
Pubmed	BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling.	TWIST1 COL1A2	4.20e-04	12	89	2	28790014
Pubmed	Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis.	GLI2 GAS1	4.20e-04	12	89	2	36459481
Pubmed	An absence of Twist1 results in aberrant cardiac neural crest morphogenesis.	TBX20 TWIST1	4.20e-04	12	89	2	18539270
Pubmed	Twist1 Is Essential for Tooth Morphogenesis and Odontoblast Differentiation.	DSPP TWIST1	4.20e-04	12	89	2	26487719
Pubmed	Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice.	CELSR2 TBX20	4.20e-04	12	89	2	20631168
Pubmed	Subtypes of medulloblastoma have distinct developmental origins.	TRIM28 GAS1 TWIST1	4.29e-04	57	89	3	21150899
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	EFNB1 CELSR2 PATZ1 GAS1 TBX20	4.77e-04	251	89	5	29031500
Pubmed	Expression patterns of Hedgehog signalling pathway members during mouse palate development.	GLI2 GAS1	4.96e-04	13	89	2	16168717
Pubmed	TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids.	TRIM28 ESR1	4.96e-04	13	89	2	15322135
Pubmed	Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.	GLI2 GAS1	4.96e-04	13	89	2	32332736
Pubmed	Linkage and association of successful aging to the 6q25 region in large Amish kindreds.	FOXQ1 COL1A2	4.96e-04	13	89	2	22773346
Pubmed	TGFbeta-mediated FGF signaling is crucial for regulating cranial neural crest cell proliferation during frontal bone development.	TWIST1 COL1A2	4.96e-04	13	89	2	16368934
Pubmed	A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.	TRIM28 ESR1	4.96e-04	13	89	2	8978696
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6C SLC2A4RG CELSR2 TRIM28 UBR4 AMBRA1 ANKHD1 ZNF865 UVRAG MADD	5.28e-04	1105	89	10	35748872
Pubmed	CTNNB1 in mesenchyme regulates epithelial cell differentiation during Müllerian duct and postnatal uterine development.	ESR1 TWIST1	5.78e-04	14	89	2	23904126
Pubmed	GATA4 as a novel regulator involved in the development of the neural crest and craniofacial skeleton via Barx1.	TWIST1 COL1A2	5.78e-04	14	89	2	29523871
Pubmed	Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.	GLI2 GAS1	5.78e-04	14	89	2	21664576
Pubmed	The role of TGF-beta signaling in regulating chondrogenesis and osteogenesis during mandibular development.	TWIST1 COL1A2	5.78e-04	14	89	2	17204263
Pubmed	Gli activity is critical at multiple stages of embryonic mammary and nipple development.	GLI2 ESR1	5.78e-04	14	89	2	24260306
Pubmed	SOX9 modulates the expression of key transcription factors required for heart valve development.	TBX20 TWIST1	5.78e-04	14	89	2	26525672
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	SLC41A2 SLC2A4RG NFATC4 NUTM2D NUP62 ANKHD1 SPOCD1 UVRAG MADD	6.09e-04	925	89	9	28986522
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRMPD4 TRO R3HDM2 ZSWIM6 MADD PDZD2	6.35e-04	407	89	6	12693553
Pubmed	TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.	TRIM28 NUP62 KDM1A OVOL2	6.42e-04	152	89	4	28192407
Pubmed	A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning.	GLI2 GAS1	6.65e-04	15	89	2	25458012
Pubmed	The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28.	IRS4 TRIM28	6.65e-04	15	89	2	25882849
Interaction	SPSB2 interactions	CELSR2 ARHGEF10 RNF185 AMBRA1 SMARCD1	2.53e-06	51	86	5	int:SPSB2
Interaction	TNPO2 interactions	FAM174A EFNB1 FCGRT TRIM8 R3HDM2 TMEM108 KDM1A OVOL2	5.18e-06	224	86	8	int:TNPO2
Interaction	ANKRD17 interactions	LONP1 ATXN2 TRIM28 ESR1 PHLPP1 ANKHD1 KDM1A OVOL2	5.53e-06	226	86	8	int:ANKRD17
Interaction	PHF13 interactions	TRIM28 TBX20 KDM1A	3.29e-05	15	86	3	int:PHF13
Interaction	ANKHD1 interactions	FOXQ1 TRIM28 GLI2 ESR1 AMBRA1 ANKHD1 KDM1A	3.87e-05	216	86	7	int:ANKHD1
Interaction	HEATR1 interactions	FAM174A FOXQ1 EFNB1 TRIM28 ESR1 PHLPP1 FOXL1	4.60e-05	222	86	7	int:HEATR1
Interaction	TLE4 interactions	UBQLN1 NUP62 TBX20 KDM1A FOXL1	4.62e-05	92	86	5	int:TLE4
Interaction	CAND2 interactions	FAM174A EFNB1 TRIM28 TMEM108 OVOL2	5.39e-05	95	86	5	int:CAND2
Interaction	HDAC3 interactions	ZBTB7A TRIM28 ESR1 SMARCD1 KDM1A TWIST1 FOXL1 OVOL2	5.75e-05	313	86	8	int:HDAC3
Interaction	KDM2B interactions	FOXQ1 GLI2 ESR1 BCORL1 KDM1A FOXL1	6.57e-05	161	86	6	int:KDM2B
Coexpression	HAY_BONE_MARROW_STROMAL	EFNB1 COL16A1 ARHGEF10 NFATC4 GLI2 GAS1 CHSY3 TMEM108 TACC2 TCF7L1 TWIST1 COL1A2	8.60e-06	767	87	12	M39209
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#5_top-relative-expression-ranked_1000	SEMA6C IRS4 COL16A1 FCGRT ESR1 BCORL1 CHSY3 COL1A2	1.49e-06	197	87	8	gudmap_developingGonad_e16.5_epididymis_1000_k5
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500	IRS4 EFNB1 COL16A1 ATXN2 PATZ1 ESR1 BCORL1 GAS1 CHSY3 COL1A2	6.31e-06	406	87	10	gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	SEMA6C IRS4 EFNB1 COL16A1 ATXN2 FCGRT PATZ1 ESR1 BCORL1 GAS1 SCPEP1 CHSY3 COL1A2	1.91e-05	790	87	13	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	SEMA6C IRS4 EFNB1 COL16A1 ATXN2 FCGRT PATZ1 ESR1 BCORL1 GAS1 SCPEP1 CHSY3 COL1A2	2.15e-05	799	87	13	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#1_top-relative-expression-ranked_500	IRS4 COL16A1 ESR1 CHSY3 COL1A2	3.82e-05	92	87	5	gudmap_developingGonad_e16.5_epididymis_500_k1
ToppCell	Pericytes-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	ADRA1D GLI2 GAS1 LGR6 TWIST1 FOXL1 COL1A2	5.37e-08	171	89	7	bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	SLC7A8 DCBLD1 CC2D2A SPOCD1 SH3D21 CD163	9.01e-07	162	89	6	7d43d59531cbefe3ac94953b7faf7156b2a31441
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SELPLG NFATC4 GLI2 CHSY3 FOXL1 COL1A2	1.08e-06	167	89	6	e228b8373ffd4436e6b944e26d0fadf3ac289b21
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SELPLG NFATC4 GLI2 CHSY3 FOXL1 COL1A2	1.08e-06	167	89	6	7cb1b11e8e24a10115e46ffbb74889e672a7a026
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SELPLG NFATC4 GLI2 CHSY3 FOXL1 COL1A2	1.08e-06	167	89	6	bb53a478b5d821d6d82c15bc4ed075b67682457c
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	GALNT10 PRDM8 COL16A1 CHSY3 SPOCD1 COL1A2	1.56e-06	178	89	6	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1D COL16A1 ESR1 GAS1 TWIST1 COL1A2	1.66e-06	180	89	6	c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1D COL16A1 ESR1 GAS1 TWIST1 COL1A2	1.66e-06	180	89	6	32c6a3886428d82fb4355d987c6d2645f333447b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 ESR1 GAS1 TWIST1 COL1A2	2.14e-06	188	89	6	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 ESR1 GAS1 TWIST1 COL1A2	2.28e-06	190	89	6	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GALNT10 COL16A1 ESR1 GAS1 TWIST1 COL1A2	2.49e-06	193	89	6	adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 NFATC4 GLI2 ESR1 CHSY3 COL1A2	2.57e-06	194	89	6	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 NFATC4 GLI2 ESR1 CHSY3 COL1A2	2.57e-06	194	89	6	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL16A1 GLI2 BCORL1 RPS6KA6 TMEM108 COL1A2	2.72e-06	196	89	6	614a07334707eafe238d5cb7b080a3ca796a1920
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 CELSR2 GLI2 ESR1 FOXL1	1.69e-05	159	89	5	330ecbba97d47bc818a5e8d1d84b05d056bd831e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 CELSR2 GLI2 ESR1 FOXL1	1.69e-05	159	89	5	cbb331eb689d8cea9e1146ba85e0a05d23301c47
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGEF10 FCGRT SCPEP1 CHSY3 UVRAG	2.02e-05	165	89	5	479962ce1c3d6636ae62b6709635299748653801
ToppCell	droplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFNB1 PATZ1 NUP62 LGR6 PDZD2	2.14e-05	167	89	5	a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 NFATC4 GLI2 ESR1 CHSY3	2.20e-05	168	89	5	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NFATC4 GLI2 CHSY3 TWIST1 COL1A2	2.47e-05	172	89	5	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NFATC4 GLI2 CHSY3 TWIST1 COL1A2	2.47e-05	172	89	5	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC7A8 NFATC4 UBR4 CD163 MADD	2.61e-05	174	89	5	d77fa525d5c87c190b4a10787b270eabd16c610f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1D COL16A1 GLI2 ESR1 COL1A2	2.68e-05	175	89	5	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ARHGEF10 DSPP GAS1 SCPEP1 COL1A2	2.75e-05	176	89	5	08f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL16A1 GLI2 GAS1 TMEM108 COL1A2	2.83e-05	177	89	5	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL16A1 GLI2 GAS1 TMEM108 COL1A2	2.83e-05	177	89	5	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	Mid-temporal_gyrus_(MTG)\|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ESR1 SCPEP1 CHSY3 TMEM108 PDZD2	2.91e-05	178	89	5	ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 NFATC4 GLI2 ESR1 COL1A2	2.91e-05	178	89	5	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	COL16A1 TRO CHSY3 SPOCD1 CD163	2.99e-05	179	89	5	cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC41A2 ARHGEF10 SCPEP1 UVRAG CD163	3.07e-05	180	89	5	64f01494a4052186773720e10b4e7c724ff94547
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PATZ1 SMARCD1 CHSY3 TMEM108 TDRG1	3.23e-05	182	89	5	d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PATZ1 SMARCD1 CHSY3 TMEM108 TDRG1	3.23e-05	182	89	5	92f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PATZ1 SMARCD1 CHSY3 TMEM108 TDRG1	3.23e-05	182	89	5	02baca9a72c7b559c3e452693b3b134af804c868
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 DUSP7 LGR6 FOXL1 COL1A2	3.32e-05	183	89	5	667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 ESR1 CHSY3 COL1A2	3.40e-05	184	89	5	c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1D COL16A1 GLI2 ESR1 COL1A2	3.40e-05	184	89	5	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NFATC4 GLI2 CHSY3 FOXL1 COL1A2	3.49e-05	185	89	5	7092436b4db90289516ed130ade596e3021cffaf
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL16A1 NFATC4 GLI2 GAS1 COL1A2	3.49e-05	185	89	5	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NFATC4 GLI2 CHSY3 FOXL1 COL1A2	3.49e-05	185	89	5	a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A8 ADRA1D CELSR2 TRO SYN1	3.68e-05	187	89	5	e04a84989d624378141042768383b9c846901f2d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A8 ADRA1D CELSR2 TRO SYN1	3.68e-05	187	89	5	24cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A8 ADRA1D CELSR2 TRO SYN1	3.68e-05	187	89	5	2f153b203fe79f206319603cf94d3a03ab49a05d
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL16A1 GLI2 TACC2 LGR6 SPOCD1	3.77e-05	188	89	5	4d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell	facs-Skin-nan-18m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDV3 FOXQ1 COL16A1 ESR1 SH3D21	3.87e-05	189	89	5	6c71e81373cb7822de23c193a6350b6df9f567bc
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL16A1 FRMPD4 GLI2 GAS1 COL1A2	3.87e-05	189	89	5	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFNB1 GAS1 TRIM8 CHSY3 TCF7L1	3.87e-05	189	89	5	d00410010283dc6191ce9857d6c7952678fed588
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 CHSY3 LGR6 COL1A2	3.97e-05	190	89	5	70c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GALNT10 COL16A1 GAS1 TWIST1 COL1A2	3.97e-05	190	89	5	4f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 ESR1 CHSY3 COL1A2	4.07e-05	191	89	5	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL16A1 FRMPD4 GLI2 GAS1 COL1A2	4.07e-05	191	89	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 ESR1 CHSY3 COL1A2	4.07e-05	191	89	5	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GLI2 GAS1 TCF7L1 FOXL1 COL1A2	4.07e-05	191	89	5	24dc77ee8de01b42559f92721655f4281b114e17
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 ESR1 CHSY3 COL1A2	4.07e-05	191	89	5	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 ESR1 CHSY3 COL1A2	4.07e-05	191	89	5	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL16A1 FRMPD4 GLI2 TMEM108 COL1A2	4.17e-05	192	89	5	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFATC4 FGD5 LGR6 MTCH1 TCF7L1	4.17e-05	192	89	5	6806a1a9fe00395dc1abc3e0124b4261dc701f31
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL16A1 FRMPD4 GLI2 GAS1 COL1A2	4.17e-05	192	89	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	Severe-Myeloid-Macrophages-FABP4+\|Severe / Condition, Lineage, Cell class and cell subclass	SLC7A8 FCGRT FGD5 SPOCD1 CD163	4.17e-05	192	89	5	30aad927ad40d8abaf9d0539bf8cb9d88d16f24d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL16A1 GLI2 ESR1 GAS1 COL1A2	4.17e-05	192	89	5	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	COL16A1 NFATC4 GLI2 GAS1 COL1A2	4.17e-05	192	89	5	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	COL16A1 GLI2 ESR1 GAS1 COL1A2	4.17e-05	192	89	5	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL16A1 GAS1 TBX20 TCF7L1 COL1A2	4.27e-05	193	89	5	64edc1d6fb0fe117767d494cf4a5723bf8be2804
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL16A1 FCGRT GAS1 MTCH1 COL1A2	4.27e-05	193	89	5	428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL16A1 FRMPD4 GLI2 TMEM108 COL1A2	4.27e-05	193	89	5	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	LA\|World / Chamber and Cluster_Paper	SLC41A2 GALNT10 GLI2 CHSY3 COL1A2	4.27e-05	193	89	5	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL16A1 GLI2 ESR1 GAS1 COL1A2	4.27e-05	193	89	5	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SLC7A8 GALNT10 FCGRT TWIST1 COL1A2	4.38e-05	194	89	5	638b9fdce64ed00243b5303800ec66207d5fd640
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal-choroid_plexus/mesenchymal-like_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SLC7A8 GALNT10 FCGRT TWIST1 COL1A2	4.38e-05	194	89	5	e9868c22934b6c0ac35e3e8270ec0b671bc6582a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 ESR1 ZAR1 COL1A2	4.38e-05	194	89	5	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL16A1 FRMPD4 GLI2 TMEM108 COL1A2	4.38e-05	194	89	5	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 NFATC4 GLI2 ESR1 COL1A2	4.38e-05	194	89	5	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL16A1 FRMPD4 GLI2 TMEM108 COL1A2	4.38e-05	194	89	5	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	390C-Myeloid-Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SLC7A8 FCGRT FGD5 SPOCD1 CD163	4.49e-05	195	89	5	ba494be431916d43c1d480f65bed674c0722c710
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 NFATC4 GLI2 CHSY3 COL1A2	4.71e-05	197	89	5	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 ESR1 CHSY3 COL1A2	4.71e-05	197	89	5	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 NFATC4 GLI2 CHSY3 COL1A2	4.71e-05	197	89	5	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 ESR1 CHSY3 COL1A2	4.71e-05	197	89	5	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL16A1 NFATC4 TWIST1 FOXL1 COL1A2	4.83e-05	198	89	5	300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL16A1 NFATC4 GLI2 GAS1 COL1A2	4.94e-05	199	89	5	21335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DSPP UBR4 FGD5 CD163 NUTM2G	4.94e-05	199	89	5	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PRDM8 ADRA1D COL16A1 NFATC4 COL1A2	5.06e-05	200	89	5	8a4c210a3130f7baedf15ecbc0f4903b97da0352
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL16A1 GLI2 ESR1 GAS1 COL1A2	5.06e-05	200	89	5	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PRDM8 ADRA1D COL16A1 TCFL5 PDZD2	5.06e-05	200	89	5	4c3c11dd5e71ebc3d62264eeaeb71a850b149779
ToppCell	VE-CD4-CD4_Treg\|VE / Condition, Cell_class and T cell subcluster	SEMA6C RPS6KA6 TACC2 LMTK3	1.30e-04	129	89	4	e89d414e1b23e1656747defa39f09b51944a2166
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRDM8 GLI2 CHSY3 COL1A2	2.04e-04	145	89	4	051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 SYN1 COL1A2	2.33e-04	150	89	4	7a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 SYN1 COL1A2	2.33e-04	150	89	4	e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
ToppCell	normal_Lymph_Node-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	CELSR2 FCGRT SLC5A9 CD163	2.51e-04	153	89	4	5424494ea1f09542799045a875cc3eac13de5079
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	FCRL2 COL16A1 ESR1 SCPEP1	2.57e-04	154	89	4	b944be7fc30d8897d52689f2b2622ff7ede8a6a1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TBX20 LRRC37B SH3D21 FOXL1	2.63e-04	155	89	4	51f6447945389649d99dcf7603b396195c631ead
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TBX20 LRRC37B SH3D21 FOXL1	2.63e-04	155	89	4	23dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1D COL16A1 GLI2 CHSY3	2.63e-04	155	89	4	82e602f31981c6b48abff2a04b2ab5d26d4462a2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADRA1D COL16A1 GLI2 CHSY3	2.63e-04	155	89	4	979c1d53b435a82c57d16707eed8ba7346326866
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 DUSP7 COL1A2	2.70e-04	156	89	4	d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RPS6KA6 MAPKAPK5-AS1 MADD COL1A2	2.70e-04	156	89	4	14e2f693a75f1075f40cc7b16ee430262a5de016
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NFATC4 TRO UBR4 ZNF865	2.70e-04	156	89	4	895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL16A1 GLI2 DUSP7 COL1A2	2.70e-04	156	89	4	363f1b661048d25895e2b8681c82894c957b29c0
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG AMBRA1 TMEM108 MADD	2.97e-04	160	89	4	5c68d6a76c59e3a7e668ae5471396478a55756ac
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG AMBRA1 TMEM108 MADD	2.97e-04	160	89	4	0fee84844733d36805e1df90ca09478169746708
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC41A2 COL16A1 SH3D21 PDZD2	3.04e-04	161	89	4	82ed45f144a07856fe92d37426c5f92e259a03a9
Disease	myocardial infarction	PRDM8 CELSR2 ATXN2 DCBLD1 FGD5 TBX20 TWIST1 FOXL1 PDZD2	8.64e-07	350	86	9	EFO_0000612
Disease	serum non-albumin protein measurement	SLC7A8 ZBTB7A ATXN2 FCGRT PHLPP1 MAPKAPK5-AS1 TCF7L1	9.08e-05	361	86	7	EFO_0004568
Disease	Arhinencephaly	GLI2 GAS1	2.32e-04	8	86	2	C0078982
Disease	colorectal cancer	UBQLN1 RTEL1 ATXN2 ARHGEF10 DCBLD1 SCPEP1 FOXL1 PDZD2	3.85e-04	604	86	8	MONDO_0005575
Disease	fetal genotype effect measurement, body weights and measures	ESR1 FGD5 TBX20	4.00e-04	49	86	3	EFO_0004324, EFO_0007959
Disease	Agents acting on the renin-angiotensin system use measurement	PRDM8 ADRA1D CELSR2 NFATC4 FGD5 TWIST1	4.49e-04	335	86	6	EFO_0009931
Disease	peripheral arterial disease	CELSR2 ATXN2 TWIST1	5.33e-04	54	86	3	EFO_0004265
Disease	complement C1q tumor necrosis factor-related protein 1 measurement	CELSR2 MTCH1	5.44e-04	12	86	2	EFO_0801493
Disease	granulins measurement	CELSR2 MTCH1	5.44e-04	12	86	2	EFO_0008141
Disease	Antithrombotic agent use measurement	PRDM8 CELSR2 TWIST1	5.62e-04	55	86	3	EFO_0009925
Disease	Global developmental delay	FRMPD4 TRIM8 SMARCD1 KDM1A	6.29e-04	133	86	4	C0557874
Disease	velocity of sound measurement	ESR1 FOXL1	6.41e-04	13	86	2	EFO_0005654
Disease	reaction time measurement	ZBTB7A ADRA1D ATXN2 MUC19 CC2D2A AMBRA1 MAPKAPK5-AS1 TACC2	6.75e-04	658	86	8	EFO_0008393
Disease	ascending aortic diameter	PRDM8 ESR1 FGD5 TBX20	7.63e-04	140	86	4	EFO_0021787
Disease	apolipoprotein A 1 measurement	SLC2A4RG CELSR2 ATXN2 RNF185 R3HDM2 UVRAG TCF7L1 CD163 MADD	8.18e-04	848	86	9	EFO_0004614
Disease	stroke	ATXN2 TMEM108 UVRAG TWIST1	8.47e-04	144	86	4	EFO_0000712
Disease	Ischemic stroke, tissue plasminogen activator measurement	ATXN2 TWIST1	8.60e-04	15	86	2	EFO_0004791, HP_0002140
Disease	Alobar Holoprosencephaly	GLI2 GAS1	8.60e-04	15	86	2	C0431363
Disease	bone density	FAM174A ESR1 AMBRA1 TACC2 TCF7L1 FOXL1	9.65e-04	388	86	6	EFO_0003923
Disease	Ischemic stroke, plasminogen activator inhibitor 1 measurement	ATXN2 TWIST1	9.81e-04	16	86	2	EFO_0004792, HP_0002140
Disease	Synostotic Posterior Plagiocephaly	EFNB1 TWIST1	9.81e-04	16	86	2	C1833340
Disease	Craniosynostosis, Type 1	EFNB1 TWIST1	9.81e-04	16	86	2	C4551902
Disease	Acrocephaly	EFNB1 TWIST1	9.81e-04	16	86	2	C0030044
Disease	Lobar Holoprosencephaly	GLI2 GAS1	9.81e-04	16	86	2	C0431362
Disease	Semilobar Holoprosencephaly	GLI2 GAS1	9.81e-04	16	86	2	C0751617
Disease	Trigonocephaly	EFNB1 TWIST1	9.81e-04	16	86	2	C0265535
Disease	Scaphycephaly	EFNB1 TWIST1	9.81e-04	16	86	2	C0265534
Disease	Synostotic Anterior Plagiocephaly	EFNB1 TWIST1	9.81e-04	16	86	2	C2931150
Disease	Metopic synostosis	EFNB1 TWIST1	9.81e-04	16	86	2	C1860819
Disease	Antihypertensive use measurement	PRDM8 ATXN2 FGD5 MADD TWIST1	1.08e-03	265	86	5	EFO_0009927
Disease	Holoprosencephaly	GLI2 GAS1	1.11e-03	17	86	2	C0079541
Disease	Brachycephaly	EFNB1 TWIST1	1.11e-03	17	86	2	C0221356
Disease	factor XI measurement, Ischemic stroke	ATXN2 TWIST1	1.11e-03	17	86	2	EFO_0004694, HP_0002140
Disease	Malignant neoplasm of breast	FOXQ1 ESR1 UBR4 BCORL1 SMARCD1 TACC2 FGD5 LGR6 SPOCD1 TCF7L1	1.13e-03	1074	86	10	C0006142
Disease	Usual Interstitial Pneumonia	RTEL1 ESR1	1.39e-03	19	86	2	C4721509
Disease	Hamman-Rich Disease	RTEL1 ESR1	1.39e-03	19	86	2	C4721508
Disease	factor VIII measurement, Ischemic stroke	ATXN2 TWIST1	1.39e-03	19	86	2	EFO_0004630, HP_0002140
Disease	Craniosynostosis	EFNB1 TWIST1	1.54e-03	20	86	2	C0010278
Disease	X-24309 measurement	ADRA1D TMEM108	1.54e-03	20	86	2	EFO_0800872
Disease	Familial Idiopathic Pulmonary Fibrosis	RTEL1 ESR1	1.54e-03	20	86	2	C4721952
Disease	Idiopathic Pulmonary Fibrosis	RTEL1 ESR1	1.70e-03	21	86	2	C1800706
Disease	progranulin measurement	UBQLN1 CELSR2	1.87e-03	22	86	2	EFO_0004625
Disease	osteoporosis (biomarker_via_orthology)	DSPP ESR1	1.87e-03	22	86	2	DOID:11476 (biomarker_via_orthology)
Disease	total blood protein measurement	SLC7A8 ZBTB7A ATXN2 FCGRT ESR1 TCF7L1	2.02e-03	449	86	6	EFO_0004536
Disease	Neoplasm Invasiveness	UBQLN1 ESR1 KDM1A TWIST1	2.09e-03	184	86	4	C0027626
Disease	linoleic acid measurement	CELSR2 ATXN2 FCGRT MTCH1	2.17e-03	186	86	4	EFO_0006807
Disease	descending aortic diameter	NFATC4 TBX20 TWIST1	2.19e-03	88	86	3	EFO_0021788
Disease	pulse pressure measurement	ZBTB7A PRDM8 ADRA1D ESR1 MYPN TRIM8 FGD5 TCF7L1 KDM1A MADD TWIST1	2.36e-03	1392	86	11	EFO_0005763
Disease	breast carcinoma (is_implicated_in)	ESR1 TWIST1	2.41e-03	25	86	2	DOID:3459 (is_implicated_in)
Disease	large artery stroke, coronary artery disease	CELSR2 TWIST1	2.41e-03	25	86	2	EFO_0001645, EFO_0005524

Protein segments in the cluster

Peptide	Gene	Start	Entry
GDSSGSGSGGAAPAF	CBARP	466	Q8N350
GGAGSSLSQGDPDAA	ARHGEF10	1251	O15013
STGASGDVGSPGFGL	COL16A1	571	Q07092
GSGSNARGADPDGSA	BCORL1	66	Q5H9F3
DAGLDNSDGSPSGNG	DSPP	236	Q9NZW4
PGDFGTTAKESSGNG	CELSR2	2791	Q9HCU4
GFPASGLATESDGGN	AMBRA1	471	Q9C0C7
TRPGDGGTASAGAAG	CDV3	56	Q9UKY7
LPGGGGGDNSGTAEN	R3HDM2	906	Q9Y2K5
SDASPEAGSGGGGVA	SLC7A8	21	Q9UHI5
SSNAGDGPGGEGSVH	MADD	1216	Q8WXG6
NQGSLSDGGGFPLSG	MAGEB17	186	A8MXT2
SGGGGFQPSGLAFAS	LGR6	951	Q9HBX8
GGSGAAVAPAAGQGS	GALNT10	41	Q86SR1
PSASDCFGSNGNGGG	ATXN2	71	Q99700
ATPGDGFPSNDSGFG	LMTK3	1396	Q96Q04
TGDGSDSRDGGFPND	DCAF8L2	51	P0C7V8
AAGTGQGDFGPNSDG	FCGRT	241	P55899
GPGSEAAAFGSNGLG	ESR1	81	P03372
GSGSAGGETIVFGPD	MUC19	231	Q7Z5P9
ASPNFNTSGGASAGG	PDZD2	691	O15018
APGEGGQAASDALGG	FGD5	441	Q6ZNL6
APSDSSGINLSGFGG	LRRC37B	781	Q96QE4
GGAFSGGEDASEGGA	LONP1	76	P36776
SILENFSGSGGGGPA	GLI2	766	P10070
AELGNGPGSSGSDGG	GAS1	246	P54826
EVFSGGGASSGEVNG	RPS6KA6	16	Q9UK32
GGFSFTGGSTAQPSG	NUP62	156	P37198
GSGSSSAGEPGGAES	OVOL2	56	Q9BRP0
PAGGFGGFGTTSTTA	NUP54	21	Q7Z3B4
SAQLGDGGAADGGPA	PATZ1	71	Q9HBE1
GFAGEKGPSGEAGTA	COL1A2	841	P08123
AAATGTEAGPGTAGG	KDM1A	16	O60341
TEAGPGTAGGSENGS	KDM1A	21	O60341
GVGSGVPFSFEADGS	CC2D2A	776	Q9P2K1
GETSDGSGLGQGDRF	FRMPD4	1136	Q14CM0
GASGGSSGDPDGFFN	EFNB1	221	P98172
AAGGTRAGSEPGAGS	DUSP7	21	Q16829
TGGDEDPGAGSASAG	MAPKAPK5-AS1	56	Q8N8E1
AEAQPEAGSGAGGSG	FOXL1	166	Q12952
PSTGDGGDTRDGGFL	DCAF8L1	46	A6NGE4
LGNSSAPSGGGASFN	FCRL2	341	Q96LA5
SGGFSPVAGVGAQDG	DCBLD1	636	Q8N8Z6
VSFSGSSNFGEGSGP	CD163	206	Q86VB7
GSDGDCAANSPAAGG	FOXQ1	41	Q9C009
AEAAGPRGSEGGNGS	FAM174A	71	Q8TBP5
SGSGSGNFGEEGNPQ	IRS4	461	O14654
TEQDGCGPSGAGASN	NUTM2D	116	Q5VT03
AGQDGRGPSGAGASN	NUTM2F	66	A1L443
AGQDGRGPSGAGASN	NUTM2G	66	Q5VZR2
DGGSGGLGSGDNAPT	MTCH1	66	Q9NZJ7
GTVGAGGEDAGPSQS	RTEL1	1191	Q9NZ71
AAATFSEQVGGGSGG	SYN1	91	P17600
DGGEGPSATANGGLS	SELPLG	371	Q14242
QSSIFGGADVGFSGG	UVRAG	481	Q9P2Y5
FPGLGSLGGQDSSGS	TDRG1	71	Q3Y452
SRDSGPNGGFQSGGS	SH3D21	186	A4FU49
GFQSVAPSGGAGASG	SMARCD1	6	Q96GM5
REAGGQGGGAFFSPS	NFATC4	156	Q14934
GGPGGSSTGFGNFEE	SCPEP1	76	Q9HB40
SEDQDAGGGGGSSTP	PRDM8	411	Q9NQV8
AGECPAGGGAAENSS	SLC5A9	591	Q2M3M2
DKTSGGPSSGGGFVD	SLC41A2	11	Q96JW4
SGTGFRGGDDPAGEA	NOXO1	301	Q8NFA2
RSSAGEPGSAGAGGD	ADRA1D	66	P25100
EPGSAGAGGDVNGTA	ADRA1D	71	P25100
LFGEAGPASGVGSSG	ANKHD1	46	Q8IWZ3
GSSHNGSGDGGAAAP	CHSY3	151	Q70JA7
AAAAGESGDIGPGSG	LINC00612	106	Q8N6U2
AAVAGAGGGASSGPE	ZNF865	776	P0CJ78
PQGSSVGGGFAGLEF	SLC2A4RG	41	Q9NR83
GSPSTGAGFGGALNT	TRO	961	Q12816
NPGFGGAFSTSAGFG	TRO	1096	Q12816
AADFGGTPSNSIGFG	TRO	1116	Q12816
SDGFGGGLGTNASFG	TRO	1286	Q12816
SSAGAAGGGDDLGAN	TCF7L1	21	Q9HCS4
PGGSGAGCASGTEKF	SPOCD1	271	Q6ZMY3
PGSQDSAAGAEGAGA	UBQLN1	11	Q9UMX0
GFPQGGVDSCSGDAG	TMPRSS9	996	Q7Z410
QDGATGSQSGPGDSA	SEMA6C	571	Q9H3T2
SFPSAGEQGGEAGAA	TACC2	1116	O95359
SAGGPSGSSNGAGES	RNF185	16	Q96GF1
SFNTGGGAAGGPGDD	ZSWIM6	126	Q9HCJ5
SGGNGSGSGAREEAP	PHLPP1	61	O60346
LDAHGEFGGGSGSSP	TBX20	61	Q9UMR3
GAAGTASGEGQSGQP	TRIM8	401	Q9BZR9
PADHGGSVGSESGGS	UBR4	2886	Q5T4S7
GGGDAALGEPGLSFT	TCFL5	26	Q9UL49
GGSSSGGGSPQSYEE	TWIST1	91	Q15672
DSGGGPGAATDGNFT	ZBTB7A	566	O95365
APAAANSSGDGGAAG	TRIM28	96	Q13263
GAEGTTGGGSFSQQP	ZAR1	141	Q86SH2
GGGSTFTSQGGTPDA	TMEM108	286	Q6UXF1
SPSGAAEGGGGQDDL	MYPN	46	Q86TC9