Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsmall GTPase binding

DMXL2 SGSM1 FGD2 PEX5L SH3BP4 INF2 RABGAP1L WDR44 XPOT

3.38e-053211009GO:0031267
GeneOntologyMolecularFunctionGTPase binding

DMXL2 SGSM1 FGD2 PEX5L SH3BP4 INF2 RABGAP1L WDR44 XPOT

8.19e-053601009GO:0051020
DomainWD40_repeat_dom

VPS11 DMXL2 UBR4 DTL PAFAH1B1 SPAG16 DMWD WDR62 WDR44

3.09e-052971009IPR017986
DomainIg_I-set

CHL1 MYOM1 NRG2 HMCN2 BSG IGSF9 CDON

7.28e-051901007IPR013098
DomainI-set

CHL1 MYOM1 NRG2 HMCN2 BSG IGSF9 CDON

7.28e-051901007PF07679
DomainWD40_repeat

DMXL2 DTL PAFAH1B1 HERC2 SPAG16 DMWD WDR62 WDR44

1.07e-042721008IPR001680
DomainWD_REPEATS_1

DMXL2 DTL PAFAH1B1 HERC2 SPAG16 DMWD WDR62 WDR44

1.24e-042781008PS00678
DomainWD_REPEATS_2

DMXL2 DTL PAFAH1B1 HERC2 SPAG16 DMWD WDR62 WDR44

1.27e-042791008PS50082
DomainWD_REPEATS_REGION

DMXL2 DTL PAFAH1B1 HERC2 SPAG16 DMWD WDR62 WDR44

1.27e-042791008PS50294
DomainIGc2

CHL1 MYOM1 NRG2 HMCN2 BSG IGSF9 CDON

2.71e-042351007SM00408
DomainIg_sub2

CHL1 MYOM1 NRG2 HMCN2 BSG IGSF9 CDON

2.71e-042351007IPR003598
Domain-

VPS11 DMXL2 DTL PAFAH1B1 SPAG16 DMWD WDR62 WDR44

4.21e-0433310082.130.10.10
DomainWD40/YVTN_repeat-like_dom

VPS11 DMXL2 DTL PAFAH1B1 SPAG16 DMWD WDR62 WDR44

4.38e-043351008IPR015943
DomainFN3

CHL1 MYOM1 KIAA0319L IGSF9 EPHA1 CDON

4.80e-041851006SM00060
DomainWD40

DMXL2 DTL PAFAH1B1 SPAG16 DMWD WDR62 WDR44

4.86e-042591007PF00400
DomainWD40

DMXL2 DTL PAFAH1B1 SPAG16 DMWD WDR62 WDR44

5.96e-042681007SM00320
DomainDwarfin

SMAD1 SMAD9

7.78e-0481002IPR013790
DomainDWB

SMAD1 SMAD9

7.78e-0481002SM00524
DomainMH2

SMAD1 SMAD9

7.78e-0481002PS51076
DomainMH1

SMAD1 SMAD9

7.78e-0481002PS51075
Domain-

SMAD1 SMAD9

7.78e-04810023.90.520.10
DomainMAD_homology_MH1

SMAD1 SMAD9

7.78e-0481002IPR013019
DomainMH2

SMAD1 SMAD9

7.78e-0481002PF03166
DomainSMAD_dom_Dwarfin-type

SMAD1 SMAD9

7.78e-0481002IPR001132
DomainFN3_dom

CHL1 MYOM1 KIAA0319L IGSF9 EPHA1 CDON

9.10e-042091006IPR003961
Domainfn3

CHL1 MYOM1 IGSF9 EPHA1 CDON

1.79e-031621005PF00041
DomainMAD_homology1_Dwarfin-type

SMAD1 SMAD9

1.81e-03121002IPR003619
DomainDWA

SMAD1 SMAD9

1.81e-03121002SM00523
DomainMH1

SMAD1 SMAD9

1.81e-03121002PF03165
DomainIG

CHL1 MYOM1 ICAM1 NRG2 HMCN2 BSG IGSF9 CDON

1.91e-034211008SM00409
DomainIg_sub

CHL1 MYOM1 ICAM1 NRG2 HMCN2 BSG IGSF9 CDON

1.91e-034211008IPR003599
DomainTBC

SGSM1 RABGAP1L TBC1D14

2.30e-03491003SM00164
DomainSMAD_FHA_domain

PNKP SMAD1 SMAD9

2.72e-03521003IPR008984
DomainRabGAP-TBC

SGSM1 RABGAP1L TBC1D14

2.87e-03531003PF00566
DomainTBC_RABGAP

SGSM1 RABGAP1L TBC1D14

3.19e-03551003PS50086
DomainRab-GTPase-TBC_dom

SGSM1 RABGAP1L TBC1D14

3.19e-03551003IPR000195
DomainSMAD_dom-like

SMAD1 SMAD9

3.24e-03161002IPR017855
Domain-

SMAD1 SMAD9

3.24e-031610022.60.200.10
DomainZZ

HERC2 DMD

4.11e-03181002PF00569
DomainZF_ZZ_2

HERC2 DMD

4.11e-03181002PS50135
DomainZF_ZZ_1

HERC2 DMD

4.11e-03181002PS01357
DomainFN3

CHL1 MYOM1 IGSF9 EPHA1 CDON

4.34e-031991005PS50853
DomainZnf_ZZ

HERC2 DMD

4.57e-03191002IPR000433
DomainZnF_ZZ

HERC2 DMD

4.57e-03191002SM00291
DomainIG_LIKE

CHL1 MYOM1 ICAM1 NRG2 HMCN2 BSG IGSF9 CDON

4.86e-034911008PS50835
Pubmed

Mouse Hoxa2 mutations provide a model for microtia and auricle duplication.

EYA1 SMAD1 SMAD9

4.46e-0611106324067355
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

SETD1A VPS11 UBR4 PEX1 GPATCH8 HERC2 DMD XPOT

5.53e-06313106838270169
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PITPNM2 SETD1A KIAA0930 ITPRIPL2 UBR4 KIAA0319L JADE1 LARS2 SH3BP4 FOCAD INF2 HERC2 DMWD CABIN1

6.87e-0611051061435748872
Pubmed

TLR4 is a regulator of trained immunity in a murine model of Duchenne muscular dystrophy.

TLR4 DMD

9.20e-062106235169163
Pubmed

Cdt2-mediated XPG degradation promotes gap-filling DNA synthesis in nucleotide excision repair.

ERCC5 DTL

9.20e-062106225483071
Pubmed

Functional variants in intercellular adhesion molecule-1 and toll-like receptor-4 genes are more frequent in children with febrile urinary tract infection with renal parenchymal involvement.

ICAM1 TLR4

9.20e-062106229028278
Pubmed

Endotoxaemia-augmented murine venous thrombosis is dependent on TLR-4 and ICAM-1, and potentiated by neutropenia.

ICAM1 TLR4

9.20e-062106227975098
Pubmed

Microfilaments facilitate TLR4-mediated ICAM-1 expression in human aortic valve interstitial cells.

ICAM1 TLR4

9.20e-062106219691982
Pubmed

Toll-like receptor 4 ablation in mdx mice reveals innate immunity as a therapeutic target in Duchenne muscular dystrophy.

TLR4 DMD

9.20e-062106225552658
Pubmed

SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation.

EYA1 SMAD1 SMAD9

9.77e-0614106320110314
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

IBA57 UBR4 DTL GPAT3 PEX1 SH3GLB2 R3HDM2 IDE LARS2 NDUFV1 INF2 SLC25A13 HERC2 PLOD1 WDR62 WDR44

1.21e-0514961061632877691
Pubmed

Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming.

TLR4 SMAD1 SMAD9

1.81e-0517106327606421
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FBF1 KIAA0319L SH3GLB2 JADE1 FOCAD

1.99e-05107106511347906
Pubmed

Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis.

EYA1 SMAD1 SMAD9

2.17e-0518106321281623
Pubmed

The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification.

ADAMTS12 SMAD1 SMAD9

2.57e-0519106329618652
Pubmed

Potential Alternative Receptors for SARS-CoV-2-Induced Kidney Damage: TLR-4, KIM-1/TIM-1, and CD147.

BSG TLR4

2.76e-053106238287815
Pubmed

The interaction between myocardial depressant factors in endotoxemic cardiac dysfunction: role of TNF-alpha in TLR4-mediated ICAM-1 expression.

ICAM1 TLR4

2.76e-053106217683945
Pubmed

Non-canonical cyclic AMP SMAD1/5/8 signalling in human granulosa cells.

SMAD1 SMAD9

2.76e-053106230953749
Pubmed

Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys.

SMAD1 SMAD9

2.76e-053106221381028
Pubmed

Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells.

RABGAP1L RNF39

2.76e-053106210585558
Pubmed

Smad1 and 5 but not Smad8 establish stem cell quiescence which is critical to transform the premature hair follicle during morphogenesis toward the postnatal state.

SMAD1 SMAD9

2.76e-053106224023003
Pubmed

Ablation of Hepatocyte Smad1, Smad5, and Smad8 Causes Severe Tissue Iron Loading and Liver Fibrosis in Mice.

SMAD1 SMAD9

2.76e-053106231127639
Pubmed

TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes.

TRPM5 TLR4

2.76e-053106232521253
Pubmed

MADR1, a MAD-related protein that functions in BMP2 signaling pathways.

SMAD1 SMAD9

2.76e-05310628653785
Pubmed

Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation.

SMAD1 SMAD9

2.76e-053106227848974
Pubmed

Activated NF-κB in bone marrow mesenchymal stem cells from systemic lupus erythematosus patients inhibits osteogenic differentiation through downregulating Smad signaling.

SMAD1 SMAD9

2.76e-053106222897816
Pubmed

15-Lipoxygenase-1 re-expression in colorectal cancer alters endothelial cell features through enhanced expression of TSP-1 and ICAM-1.

ICAM1 ALOX15

2.76e-053106228757355
Pubmed

Fgf9 signaling regulates small intestinal elongation and mesenchymal development.

ICAM1 SMAD1 SMAD9

3.02e-0520106318653563
Pubmed

Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.

EYA1 SMAD1 SMAD9

4.66e-0523106318787044
Pubmed

Molecular reclassification of Crohn's disease by cluster analysis of genetic variants.

TLR4 GPC5 HERC2

4.66e-0523106320886065
Pubmed

A crucial role of a high mobility group protein HMGA2 in cardiogenesis.

SMAD1 SMAD9

5.50e-054106218425117
Pubmed

Bone morphogenetic protein 4 promotes mammalian oogonial stem cell differentiation via Smad1/5/8 signaling.

SMAD1 SMAD9

5.50e-054106223993924
Pubmed

Inhibition of mTORC1 kinase activates Smads 1 and 5 but not Smad8 in human prostate cancer cells, mediating cytostatic response to rapamycin.

SMAD1 SMAD9

5.50e-054106222452883
Pubmed

Characterization of new bone morphogenetic protein (Bmp)-2 regulatory alleles.

SMAD1 SMAD9

5.50e-054106228401685
Pubmed

PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress.

DTL IL17RB

5.50e-054106227906959
Pubmed

Sulphoraphane inhibited the expressions of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 through MyD88-dependent toll-like receptor-4 pathway in cultured endothelial cells.

ICAM1 TLR4

5.50e-054106220880684
Pubmed

Downregulation of Grem1 expression in the distal limb mesoderm is a necessary precondition for phalanx development.

SMAD1 SMAD9

5.50e-054106234719843
Pubmed

Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice.

SMAD1 SMAD9

5.50e-054106217967875
Pubmed

Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal.

ABCA4 TLR4

5.50e-054106223572532
Pubmed

KMUP-1 Promotes Osteoblast Differentiation Through cAMP and cGMP Pathways and Signaling of BMP-2/Smad1/5/8 and Wnt/β-Catenin.

SMAD1 SMAD9

5.50e-054106225536014
Pubmed

Serotonin induces Rho/ROCK-dependent activation of Smads 1/5/8 in pulmonary artery smooth muscle cells.

SMAD1 SMAD9

5.50e-054106219244313
Pubmed

Signal transduction of bone morphogenetic protein receptors.

SMAD1 SMAD9

5.50e-054106214687659
Pubmed

Nuclear Export of Smads by RanBP3L Regulates Bone Morphogenetic Protein Signaling and Mesenchymal Stem Cell Differentiation.

SMAD1 SMAD9

5.50e-054106225755279
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

KIAA0930 MBOAT7 ACTR10 UBR4 PLPPR3 NDUFV1 INF2 BSG HERC2 DMWD

5.55e-056971061028298427
Pubmed

Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.

IBA57 MBOAT7 IDE LARS2 NDUFV1 BSG HERC2 PLOD1

6.10e-05438106832628020
Pubmed

Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation.

EYA1 SMAD1 SMAD9

6.80e-0526106323974041
Pubmed

Tagging genes with cassette-exchange sites.

DDX17 UBR4 JADE1 GPATCH8 BSG RABGAP1L XPOT

7.79e-05335106715741177
Pubmed

Genetic risk profiling and prediction of disease course in Crohn's disease patients.

TLR4 GPC5 HERC2

8.53e-0528106319422935
Pubmed

Betulinic acid synergically enhances BMP2-induced bone formation via stimulating Smad 1/5/8 and p38 pathways.

SMAD1 SMAD9

9.15e-055106227188281
Pubmed

Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells.

SMAD1 SMAD9

9.15e-055106211121043
Pubmed

B-cell translocation gene 2 (Btg2) regulates vertebral patterning by modulating bone morphogenetic protein/smad signaling.

SMAD1 SMAD9

9.15e-055106215542835
Pubmed

Grainyhead-like 2 interacts with noggin to regulate tissue fusion in mouse.

SMAD1 SMAD9

9.15e-055106238300806
Pubmed

Sphingosine-1-phosphate/S1PR2-mediated signaling triggers Smad1/5/8 phosphorylation and thereby induces Runx2 expression in osteoblasts.

SMAD1 SMAD9

9.15e-055106227612439
Pubmed

Histone methyltransferase Setdb1 is indispensable for Meckel's cartilage development.

SMAD1 SMAD9

9.15e-055106227890611
Pubmed

Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice.

SMAD1 SMAD9

9.15e-055106226735394
Pubmed

Congenital semilunar valvulogenesis defect in mice deficient in phospholipase C epsilon.

SMAD1 SMAD9

9.15e-055106215743817
Pubmed

Smad8B, a Smad8 splice variant lacking the SSXS site that inhibits Smad8-mediated signalling.

SMAD1 SMAD9

9.15e-055106210583507
Pubmed

The transcriptional cofactor Jab1/Cops5 is crucial for BMP-mediated mouse chondrocyte differentiation by repressing p53 activity.

SMAD1 SMAD9

9.15e-055106233393086
Pubmed

Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development.

SMAD1 SMAD9

9.15e-055106216813523
Pubmed

Requirement of Oct3/4 function for germ cell specification.

SMAD1 SMAD9

9.15e-055106218395706
Pubmed

Long noncoding RNA BMPR1B-AS1 stability regulated by IGF2BP2 affects the decidualization in endometriosis patients through the SMAD1/5/9 pathway.

SMAD1 SMAD9

9.15e-055106238703029
Pubmed

Paracrine osteogenic signals via bone morphogenetic protein-2 accelerate the atherosclerotic intimal calcification in vivo.

SMAD1 SMAD9

9.15e-055106220651281
Pubmed

Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation.

CDH15 CDON

9.15e-055106212634428
Pubmed

Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections.

SMAD1 SMAD9

9.15e-055106225141865
Pubmed

The TGFβ pathway is a key player for the endothelial-to-hematopoietic transition in the embryonic aorta.

SMAD1 SMAD9

9.15e-055106229253505
Pubmed

The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling.

SMAD1 SMAD9

9.15e-055106221246655
Pubmed

Endoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC.

SMAD1 SMAD9

9.15e-055106218775991
Pubmed

A DNA-binding domain in the C-terminal region of Cdt2 enhances the DNA synthesis-coupled CRL4Cdt2 ubiquitin ligase activity for Cdt1.

DTL IL17RB

9.15e-055106230649446
Pubmed

FGF-2 enhances Runx-2/Smads nuclear localization in BMP-2 canonical signaling in osteoblasts.

SMAD1 SMAD9

9.15e-055106223559326
Pubmed

Endoglin is involved in BMP-2-induced osteogenic differentiation of periodontal ligament cells through a pathway independent of Smad-1/5/8 phosphorylation.

SMAD1 SMAD9

9.15e-055106219918795
Pubmed

Self-organized BMP signaling dynamics underlie the development and evolution of digit segmentation patterns in birds and mammals.

SMAD1 SMAD9

9.15e-055106238175868
Pubmed

Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men.

ICAM1 PLOD1

9.15e-055106217390085
Pubmed

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.

SGSM1 FGD2 LARS2 WSCD2 CABIN1

1.31e-04159106524927181
Pubmed

Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium.

SMAD1 SMAD9

1.37e-04610629256479
Pubmed

PDGF-AA promotes osteogenic differentiation and migration of mesenchymal stem cell by down-regulating PDGFRα and derepressing BMP-Smad1/5/8 signaling.

SMAD1 SMAD9

1.37e-046106225470749
Pubmed

BMP/SMAD signaling regulates the cell behaviors that drive the initial dorsal-specific regional morphogenesis of the otocyst.

SMAD1 SMAD9

1.37e-046106220837004
Pubmed

BMP signaling orchestrates a transcriptional network to control the fate of mesenchymal stem cells in mice.

SMAD1 SMAD9

1.37e-046106228576771
Pubmed

Regeneration of axons in injured spinal cord by activation of bone morphogenetic protein/Smad1 signaling pathway in adult neurons.

SMAD1 SMAD9

1.37e-046106221518886
Pubmed

Vertebrate crossveinless 2 is secreted and acts as an extracellular modulator of the BMP signaling cascade.

SMAD1 SMAD9

1.37e-046106215188429
Pubmed

Transcriptomic profiling of human choriodecidua during term labor: inflammation as a key driver of labor.

ICAM1 TLR4

1.37e-046106225283845
Pubmed

SMAD expression in the testis: an insight into BMP regulation of spermatogenesis.

SMAD1 SMAD9

1.37e-046106218069690
Pubmed

The dorsal aorta initiates a molecular cascade that instructs sympatho-adrenal specification.

SMAD1 SMAD9

1.37e-046106222723422
Pubmed

Smad7 is required for the development and function of the heart.

SMAD1 SMAD9

1.37e-046106218952608
Pubmed

Lack of the bone morphogenetic protein BMP6 induces massive iron overload.

SMAD1 SMAD9

1.37e-046106219252488
Pubmed

Development of bat flight: morphologic and molecular evolution of bat wing digits.

SMAD1 SMAD9

1.37e-046106216618938
Pubmed

Mesenchymal bone morphogenetic protein signaling is required for normal pancreas development.

SMAD1 SMAD9

1.37e-046106220522595
Pubmed

Quantitative analysis of signaling responses during mouse primordial germ cell specification.

SMAD1 SMAD9

1.37e-046106234184730
Pubmed

Hypoxia and Reactive Oxygen Species Homeostasis in Mesenchymal Progenitor Cells Define a Molecular Mechanism for Fracture Nonunion.

SMAD1 SMAD9

1.37e-046106227250101
Pubmed

ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration.

SMAD1 SMAD9

1.37e-046106220042635
Pubmed

BMP signaling suppresses Gemc1 expression and ependymal differentiation of mouse telencephalic progenitors.

SMAD1 SMAD9

1.37e-046106233436697
Pubmed

Dynamic regulation of Smad expression during mesenchyme to epithelium transition in the metanephric kidney.

SMAD1 SMAD9

1.37e-046106211850197
Pubmed

BMP4-Smad signaling pathway mediates adriamycin-induced premature senescence in lung cancer cells.

SMAD1 SMAD9

1.37e-046106219269967
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

DMXL2 MBOAT7 ACTR10 KIAA0319L GPAT3 PEX1 SH3BP4 INF2

1.60e-04504106834432599
Pubmed

Regulation of transforming growth factor-beta and bone morphogenetic protein signalling by transcriptional coactivator GCN5.

SMAD1 SMAD9

1.91e-047106215009097
Pubmed

Noggin is required for early development of murine upper incisors.

SMAD1 SMAD9

1.91e-047106222302143
Pubmed

Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation.

SMAD1 SMAD9

1.91e-047106225758226
Pubmed

Fibroblast growth factor 2 inhibits bone morphogenetic protein 9-induced osteogenic differentiation of mesenchymal stem cells by repressing Smads signaling and subsequently reducing Smads dependent up-regulation of ALK1 and ALK2.

SMAD1 SMAD9

1.91e-047106223680673
Pubmed

Cnn3 regulates neural tube morphogenesis and neuronal stem cell properties.

SMAD1 SMAD9

1.91e-047106229151265
Pubmed

Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity.

SMAD1 SMAD9

1.91e-047106216624858
Pubmed

HtrA1 is upregulated during RANKL-induced osteoclastogenesis, and negatively regulates osteoblast differentiation and BMP2-induced Smad1/5/8, ERK and p38 phosphorylation.

SMAD1 SMAD9

1.91e-047106224269886
Cytoband22q11.23

SGSM1 LRP5L CABIN1

2.58e-0453106322q11.23
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

CHL1 MYOM1 NRG2 HMCN2 BSG IGSF9 CDON

2.92e-06161707593
GeneFamilyWD repeat domain containing

DMXL2 DTL PAFAH1B1 SPAG16 DMWD WDR62 WDR44

6.82e-05262707362
GeneFamilyImmunoglobulin like domain containing

CHL1 ICAM1 HMCN2 BSG IGSF9 CDON

1.02e-04193706594
GeneFamilyFibronectin type III domain containing

CHL1 MYOM1 IGSF9 EPHA1 CDON

3.88e-04160705555
GeneFamilySMAD family

SMAD1 SMAD9

4.08e-048702750
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

HERC2 DMD

2.17e-031870291
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#5

FGD2 PLEKHF2 EYA1 THSD7B INKA2 SH3BP4 SLC25A13 RABGAP1L IGSF9 ALOX15 CDON

2.85e-0639110211Facebase_RNAseq_e9.5_Olfactory Placode_2500_K5
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#3

FGD2 PLEKHF2 EYA1 THSD7B SH3BP4 RABGAP1L IGSF9 ALOX15 CDON

9.07e-062831029Facebase_RNAseq_e9.5_Olfactory Placode_1000_K3
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000

ITPRIPL2 FGD2 PLEKHF2 EYA1 THSD7B LARS2 SH3BP4 TRPM5 SLC25A13 RABGAP1L IGSF9 GPC5 DMD ALOX15 WDR62 CDON

1.56e-0597310216Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

SETD1A DMXL2 TCAF1 CCDC28A THSD7B DNAH7 CLIP4 FOCAD BBX RABGAP1L PAFAH1B1 WDR44 CDON XPOT

2.66e-0579510214gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#5

FGD2 SH3GLB2 EYA1 THSD7B INKA2 RABGAP1L IGSF9 ALOX15 CDON

1.49e-044061029Facebase_RNAseq_e10.5_Olfactory Pit_2500_K5
CoexpressionAtlasPlasmacytoid, DC.pDC.8+.Sp, GR1-PE CD11c-eFluor750 CD8-eFluor480 CD45-APC B220, Spleen, avg-3

KIAA0930 FGD2 JADE1 EYA1 SH3BP4 RABGAP1L IL17RB MAP3K19 ADAP2

1.58e-044091029GSM605840_500
CoexpressionAtlasPlasmacytoid, DC.pDC.8+.MLN, B220-FITC CD45-APC CD11c-eFluor780 GR1-PE CD8-eFlu, Lymph Node, avg-2

KIAA0930 FGD2 JADE1 EYA1 SH3BP4 RABGAP1L IL17RB MAP3K19 ADAP2

1.61e-044101029GSM854297_500
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 VWC2 DMXL2 ZSWIM3 GPAT3 SLC25A13

4.06e-06176106627e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DTL R3HDM2 PEX5L INKA2 INF2 RNF39

5.57e-06186106656c139e679d640ea901ead657a8e8887e0fca098
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SETD1A DMXL2 FOCAD PRMT6 SLC25A13 ADAP2

5.57e-06186106674eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SETD1A DMXL2 FOCAD PRMT6 SLC25A13 ADAP2

5.75e-0618710661eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

VWC2 MYOM1 GPAT3 RABGAP1L GPC5 DMD

7.09e-061941066c3535f7cc0076653c72db582047cff053c322397
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 ITPRIPL2 GPAT3 THSD7B BSG TBC1D14

7.30e-061951066f7d9adadd37209ce1a38e5d621607b9c9270fed8
ToppCellMonocytes-cDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

KIAA0930 ITPRIPL2 FGD2 GPAT3 SH3BP4 ADAP2

7.74e-0619710663388c104af4c6a05988e102627e0c5e34d9dcc45
ToppCellMonocytes|World / Immune cells in Kidney/Urine in Lupus Nephritis

DMXL2 KIAA0930 ITPRIPL2 FGD2 TLR4 ADAP2

7.97e-0619810668beccf03c9ec9cd02a96107a9d7ca9a6764c6a61
ToppCellCOVID-19_Moderate-Non-classical_Monocyte|World / disease group, cell group and cell class

DMXL2 KIAA0930 FGD2 CLIP4 TLR4 ADAP2

7.97e-0619810668449934e20bb2a34079fb642cae0d4647b9efe51
ToppCellCiliated_cells-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

EYA1 DNAH7 C11orf97 ALOX15 MAP3K19

3.07e-0515110659d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

DMXL2 ICAM1 PEX1 IRAG1 TLR4

3.27e-0515310655424494ea1f09542799045a875cc3eac13de5079
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

KIAA0930 ZSWIM3 UBR4 NRG2 TLR4

3.48e-05155106515bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

VWC2 SGSM1 NRG2 SH3BP4 GPC5

3.82e-0515810657960337d87afecf2692ab65e5991f052ceddfacc
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPAT3 JADE1 TMCO4 TBC1D14 SMAD9

4.56e-051641065d847d509bb1791638032ade6755d8164586b5bd5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPAT3 THSD7B SH3BP4 TMCO4 TBC1D14

4.97e-051671065edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DTL PEX5L INKA2 INF2 RNF39

5.41e-05170106567415b098e8ba815b501e557192a9f2b10ee995a
ToppCelldroplet-Kidney-KIDNEY-1m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCAF1 ITPRIPL2 FGD2 TLR4 IGSF9

5.56e-051711065d9ad6a3bce3556abd24af1630bf4a99594437c3a
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

DTL R3HDM2 INKA2 CACNG8 MAP3K19

6.20e-051751065ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

DTL R3HDM2 INKA2 CACNG8 MAP3K19

6.20e-05175106521f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GINS3 ABCA4 GPAT3 TMCO4 CDON

6.37e-0517610653766e0533b103ec92ac75eba3df02e287efc53fa
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GINS3 ABCA4 GPAT3 TMCO4 CDON

6.37e-051761065aa1bada2175d8370fc71939a607407155259d195
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 DTL TLR4 ALOX15 WDR62

6.55e-0517710651d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPAT3 JADE1 THSD7B SH3BP4 TBC1D14

6.90e-051791065e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|390C / Donor, Lineage, Cell class and subclass (all cells)

SETD1A DMXL2 FOCAD PRMT6 ADAP2

7.66e-051831065228092290dbb08785c4eda224e3ad03e99e10fab
ToppCell3'_v3-GI_small-bowel-Myeloid_Dendritic|GI_small-bowel / Manually curated celltypes from each tissue

FGD2 SH3BP4 DMD ALOX15 ADAP2

7.66e-0518310656109199cf25b28831193a5ed7925b5bf38c6eb43
ToppCell3'_v3-GI_small-bowel-Myeloid_Dendritic-DC1|GI_small-bowel / Manually curated celltypes from each tissue

FGD2 SH3BP4 DMD ALOX15 ADAP2

7.86e-0518410658e393eea7240584a3cef718bee094e2705ec1891
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

MBOAT7 ICAM1 NEK1 INF2 SLC25A13

8.27e-051861065b9e0a819cd0b250f077b26eba99e6986d68d647b
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHL1 ZSWIM3 CCDC28A PEX5L ADAMTS12

8.48e-0518710658e8b147258982b359447add5027318f5b6d51963
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

VWC2 THSD7B CYP4X1 ALOX15 CDON

8.70e-0518810659655a4c47b644a870017d349b99063e17dbae572
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 NRG2 IRAG1 CLIP4 DMD

8.70e-051881065f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellfacs-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 IRAG1 PEX5L DMD CDH15

8.70e-051881065794fc1d9a726945c42f7eac221eed938309b47a9
ToppCellcontrol-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KIAA0930 UBR4 KIAA0319L TTC31 IGSF9

8.92e-051891065bdfd120900ba58d5e54765f7b576e1f8cc2401bf
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPAT3 JADE1 THSD7B BSG TBC1D14

9.14e-051901065bb3b396d78887d5d6f93a05c8ed4d703591bf33f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 NRG2 IRAG1 CLIP4 DMD

9.14e-051901065938d1f66094b1c94606e0d40213a39e5112f3322
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 IRAG1 INKA2 DMD ADAP2

9.14e-0519010651ab3f19f1ce9f58e5125135704d94655a2e330a0
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

VWC2 MYOM1 RABGAP1L GPC5 DMD

9.37e-05191106525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLPPR3 DNAH7 SPAG16 ALOX15 MAP3K19

9.37e-051911065683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

VWC2 MYOM1 GPAT3 RABGAP1L DMD

9.37e-0519110655d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

DMXL2 FGD2 TLR4 TBC1D14 ADAP2

9.60e-051921065a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellLAM-Epithelial-AirwayEpi|LAM / Condition, Lineage and Cell class

DNAH7 CYP4X1 C11orf97 ALOX15 MAP3K19

9.60e-0519210657404fc65be3b7bd09447725b43fa31819004dfee
ToppCellMonocytes-Inflammatory_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

DMXL2 FGD2 IRAG1 TLR4 ADAP2

9.60e-0519210654be5c2c946337cd3e710137726358adca563f146
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

EYA1 DNAH7 C11orf97 SPAG16 ALOX15

9.60e-051921065eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

DNAH7 CYP4X1 SPAG16 ALOX15 MAP3K19

9.84e-051931065a0baa8be6f590b2031fede22be588715ae458e93
ToppCellhealthy_donor-Myeloid-Monocytic-CD16+_Monocyte|healthy_donor / Disease condition, Lineage, Cell class and subclass

DMXL2 KIAA0930 FGD2 TLR4 CYP4F22

1.01e-041941065ecf746ef1c5c4d6d9ca06a6d3e3778670b5700c2
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MYOM1 GPAT3 RABGAP1L GPC5 DMD

1.01e-04194106589812fb164065041357bb37a3c2d87028ec3de4e
ToppCell21-Trachea-Immune-Hematopoietic,_Macrophage|Trachea / Age, Tissue, Lineage and Cell class

FGD2 ICAM1 GPAT3 TLR4 ADAP2

1.01e-0419410653c4ac5f91b10802990b84db3406f5e71f8ee8b74
ToppCellMonocytes-Inflammatory_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

DMXL2 IRAG1 CLIP4 CYP4F22 SMAD1

1.01e-04194106528d19105123b015f8aa25ea8e6c078f630d4ba80
ToppCellCOVID-19-Myeloid-Monocyte-derived_macrophages|COVID-19 / group, cell type (main and fine annotations)

DMXL2 FGD2 TLR4 TBC1D14 ADAP2

1.03e-041951065c172c5599379c29123340621a36bfb1fc90c2115
ToppCelldistal-Epithelial-Proximal_Ciliated|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLPPR3 DNAH7 C11orf97 ALOX15 MAP3K19

1.03e-041951065abe7998421dc59bdae35c0c2251c4a1ebef5e021
ToppCelldistal-Epithelial-Proximal_Ciliated-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLPPR3 DNAH7 C11orf97 ALOX15 MAP3K19

1.03e-0419510650e3f74e0877d33c11f048b9be8394596cf5c9c4c
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DNAH7 C11orf97 SPAG16 ALOX15 MAP3K19

1.06e-041961065de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellCOVID-19_Moderate-Non-classical_Monocyte|COVID-19_Moderate / disease group, cell group and cell class

DMXL2 IRAG1 CLIP4 TLR4 ADAP2

1.06e-041961065256c557fa11414c9d2cbb1fcff33f482ee1c78ac
ToppCellcontrol-immature_Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KIAA0930 UBR4 KIAA0319L TTC31 IGSF9

1.06e-041961065e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 C11orf97 SPAG16 ALOX15 MAP3K19

1.08e-04197106591637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellNS-critical-d_0-4-Epithelial-Ciliated-diff|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH7 C11orf97 SPAG16 ALOX15 MAP3K19

1.08e-04197106562e20ef825b92908d7732aa625dcff7b95ef6ca8
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 C11orf97 SPAG16 ALOX15 MAP3K19

1.08e-04197106522c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCelldistal-Hematologic-Platelet/Megakaryocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DNAH7 CYP4X1 IGSF9 C11orf97 ALOX15

1.08e-041971065751ffb8792058384079ebfe94872b3525f1aea84
ToppCelldistal-Hematologic-Platelet/Megakaryocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DNAH7 CYP4X1 IGSF9 C11orf97 ALOX15

1.08e-041971065e28b1b154d9588dce07c123b36f7f01fa90a5fc1
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 C11orf97 SPAG16 ALOX15 MAP3K19

1.08e-0419710653bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 C11orf97 SPAG16 ALOX15 MAP3K19

1.08e-04197106587db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCelldistal-3-Epithelial-Proximal_Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLPPR3 DNAH7 C11orf97 ALOX15 MAP3K19

1.08e-04197106515b4d1203943ce90a7083178d4a4284d9b323071
ToppCellCOVID-19-Myeloid|COVID-19 / group, cell type (main and fine annotations)

DMXL2 FGD2 TLR4 TBC1D14 ADAP2

1.11e-04198106533f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMXL2 FGD2 ICAM1 TLR4 ADAP2

1.11e-041981065dbae6a58cb3ce8612755fbdba6194b70b35f258a
ToppCellmild-Myeloid-CD16_Monocytes|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIAA0930 FGD2 RPS12 SLC25A3 CYP4F22

1.11e-041981065ba97ff6e9d400b53ad013dce54afd7154a0f4fc9
ToppCelldistal-Epithelial-Ciliated-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLPPR3 DNAH7 C11orf97 ALOX15 MAP3K19

1.11e-041981065d30d6c6a0a78b7571318b5b2a0186df96dd0f5a9
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 C11orf97 SPAG16 ALOX15 MAP3K19

1.11e-041981065d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellPBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIAA0930 FGD2 IRAG1 TLR4 ADAP2

1.14e-04199106599eec995aa20ac22a8dd045382bd15a15db0b87a
ToppCelldistal-1-Epithelial-Ciliated|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLPPR3 DNAH7 C11orf97 ALOX15 MAP3K19

1.14e-0419910654120e4a2bc05adebe1e1e9670ed7ea55142eb83d
ToppCellPBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

KIAA0930 FGD2 IRAG1 TLR4 ADAP2

1.14e-041991065aca9f75c690c6ed952bcbdc7e1e7eef7719f54ca
ToppCellPBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIAA0930 FGD2 IRAG1 TLR4 ADAP2

1.14e-0419910653e09b3c2e2c57e5248981293020d2434e898e3e1
ToppCellPBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KIAA0930 FGD2 IRAG1 TLR4 ADAP2

1.14e-041991065ae6b4b4557c6a9223acdee2a79bc780c5916d38a
ToppCellmild_COVID-19_(asymptomatic)-Classical_Monocyte|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

DMXL2 KIAA0930 MBOAT7 TLR4 ADAP2

1.14e-04199106573a98d19871ffbc3c631de330998d42e9afa6da2
ToppCellPBMC-Convalescent-Myeloid-Non-classical_Monocyte|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

KIAA0930 FGD2 IRAG1 TLR4 ADAP2

1.14e-0419910654eed28ef8c74d7131eeeabdd732a682d91e034dd
ToppCellPBMC-Convalescent-Myeloid-Non-classical_Monocyte|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIAA0930 FGD2 IRAG1 TLR4 ADAP2

1.14e-041991065f234533254fd82b1ef2041e8405fe201d874018b
ToppCellCOVID-19_Convalescent-Myeloid-Non-classical_Monocyte|COVID-19_Convalescent / Disease group, lineage and cell class

KIAA0930 FGD2 IRAG1 TLR4 ADAP2

1.14e-0419910655253948a1d7fc3da571860e14cdde4e18222e13b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IRAG1 DNAH7 BSG GPC5 IL17RB

1.16e-0420010657a8160e6477708f22e48c609bf8f43f3715dcb03
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

DNAH7 C11orf97 SPAG16 ALOX15 MAP3K19

1.16e-042001065bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellInfluenza|World / Disease, condition lineage and cell class

DMXL2 KIAA0930 MBOAT7 ICAM1 TLR4

1.16e-042001065df996c35907a1c9194b9e2ca30e81f520ca067f0
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NRG2 EYA1 SLC13A2 CYP4X1 DMD

1.16e-0420010657c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellCOVID-19-COVID-19_Convalescent-Myeloid-CD16+_Monocyte|COVID-19_Convalescent / Disease, condition lineage and cell class

KIAA0930 FGD2 IRAG1 TLR4 ADAP2

1.16e-042001065f24abb2d54d6423ee886285e3c66a874ec59e1a3
ToppCellsevere-CD163+_Monocytes_(Sample_ID1_d7)|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DMXL2 ITPRIPL2 FGD2 TLR4 ADAP2

1.16e-0420010654943fe826d5fcc3dfeb8b99a7415848f3fecc994
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GPAT3 IGSF9 RNF39 CDH15

2.00e-04121106405c40fd39e6b6275f35aaad835f95a81fcbb0990
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 PLEKHF2 CYP4F22 IL17RB

2.63e-0413010641720f16ac06951c3f57b6c3b0944670a571203d1
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF140 MYOM1 FGD2 ADAP2

3.13e-041361064186be8e1595608004b8216892cb9c7a7f31fbb4d
ToppCellPND07-28-samps-Lymphocyte-B_cell-B_cell_2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

VWC2 TRPM5 RABGAP1L CDH15

3.21e-0413710642544d1256f11da6e3bad24a871b2253e0ab20d01
ToppCellPND07-28-samps-Lymphocyte-B_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

VWC2 TRPM5 RABGAP1L CDH15

3.21e-041371064874e2eaa7846a2832f46b77c726d79f220a4a1cd
ToppCellprimary_visual_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

PITPNM2 SGSM1 SLC25A3 RNF39

3.58e-041411064605d7b28e99c943f64b4095855a6f9f70e92cb09
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

EYA1 DNAH7 SPAG16 ALOX15

4.64e-0415110648216462e723fec2797387929dde095370947e10a
ToppCellCOVID-19-lung-Mesothelial|lung / Disease (COVID-19 only), tissue and cell type

PEX5L IGSF9 ALOX15 CDON

5.25e-041561064e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EYA1 SH3BP4 RABGAP1L MAP3K19

5.38e-041571064fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EYA1 SH3BP4 RABGAP1L MAP3K19

5.38e-04157106466a191cef4aa00811bb04462310d012610006f85
ToppCellfacs-Thymus-Flowthrough-24m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EYA1 SLC13A2 RABGAP1L GPC5

5.51e-041581064c870fd17213129943562487338e2669e2930d719
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DTL INKA2 IGSF9 RNF39

5.51e-041581064c8af8964a140acb2987e3b4906d72c546108d229
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

NDST4 THSD7B GPC5 DMD

5.64e-0415910645335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

IRAG1 PEX5L ADAMTS12 DMD

5.77e-041601064fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IBA57 ZSWIM3 INKA2 PRMT6

5.77e-0416010645cc1b75e3c20d83112b3aa2f3c749a6c73910a2d
ToppCellmild-Myeloid-CD14_Monocytes_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIAA0930 FGD2 SMAD1 ADAP2

5.77e-041601064a83568cd8a0b05642bacd43a8ec443e5ce314c4d
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWC2 TRPM5 SLC25A13 IL17RB

6.05e-041621064ded08da888d8c481f0f96d1e0bfd03d617966910
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

GINS3 THSD7B CYP4F22 DMD

6.19e-04163106419c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IRAG1 ADAMTS12 PNMA6F DMD

6.19e-041631064bbc078761c5043af13d9a6fcf3145a3e300bae5e
Diseaseelectroencephalogram measurement

SGSM1 SH3BP4 FOCAD DMD

1.24e-04741014EFO_0004357
Diseasemitochondrial metabolism disease (implicated_via_orthology)

LARS2 NDUFV1 SLC25A3

2.35e-04351013DOID:700 (implicated_via_orthology)
Diseaseinterleukin-17 receptor B measurement

PLOD1 IL17RB

2.41e-0471012EFO_0801719
Diseaseperoxisomal biogenesis disorder (implicated_via_orthology)

PEX1 PEX5L

3.20e-0481012DOID:0080377 (implicated_via_orthology)
DiseaseIdiopathic pulmonary hypertension

SMAD1 SMAD9

4.11e-0491012C0152171
Diseaseotitis media (is_marker_for)

ICAM1 TLR4

5.13e-04101012DOID:10754 (is_marker_for)
Diseaseallergic conjunctivitis (is_marker_for)

ICAM1 TLR4

5.13e-04101012DOID:11204 (is_marker_for)
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

SMAD1 SMAD9

8.83e-04131012DOID:0050787 (implicated_via_orthology)
Diseaseclonal hematopoiesis mutation measurement

SETD1A SH3BP4 HERC2

8.97e-04551013EFO_0020949
DiseaseSchizophrenia

CHL1 SETD1A ICAM1 IDE LARS2 NDUFV1 ADAMTS12 CACNG8 PAFAH1B1 TLR4

9.03e-0488310110C0036341
Diseaseosteoarthritis

PITPNM2 THSD7B SLC25A13 RABGAP1L SPAG16

1.02e-032221015MONDO_0005178
DiseaseAstigmatism

SGSM1 THSD7B GPC5 HERC2

1.03e-031291014HP_0000483
Disease2-oxo-hept-3-ene-1,7-dioate hydratase activity

SMAD1 SMAD9

1.03e-03141012C1150929
DiseaseAtherosclerosis

ICAM1 TLR4 ALOX15

1.10e-03591013C0004153
DiseaseAtherogenesis

ICAM1 TLR4 ALOX15

1.10e-03591013C1563937
Diseaseunipolar depression, mood disorder

BBX RABGAP1L PAFAH1B1 TLR4

1.18e-031341014EFO_0003761, EFO_0004247
DiseasePeroxisome biogenesis disorders

PEX1 PEX5L

1.18e-03151012C1832200
Diseasehair colour measurement

CHL1 KIAA0930 NRG2 MFSD4B ADAMTS12 HERC2 CDH15 SMAD9

1.26e-036151018EFO_0007822
Diseasecutaneous melanoma, hair color

KIAA0930 HERC2 CDH15

1.27e-03621013EFO_0000389, EFO_0003924
Diseasecholesteatoma of middle ear (is_marker_for)

ICAM1 TLR4

1.35e-03161012DOID:10964 (is_marker_for)
DiseaseIdiopathic pulmonary arterial hypertension

SMAD1 SMAD9

1.35e-03161012C3203102
DiseaseFamilial primary pulmonary hypertension

SMAD1 SMAD9

1.53e-03171012C0340543
Diseaseskin sensitivity to sun

ADAMTS12 HERC2

1.91e-03191012EFO_0004795
Diseaseglomerulonephritis (biomarker_via_orthology)

ALOX15 SMAD1

2.12e-03201012DOID:2921 (biomarker_via_orthology)
Diseaseunipolar depression, memory performance, cognitive function measurement

GPC5 RNF39

2.12e-03201012EFO_0003761, EFO_0004874, EFO_0008354
Diseasefeeling miserable measurement

BBX RABGAP1L PAFAH1B1

2.55e-03791013EFO_0009598
DiseaseKidney Failure

INF2 TLR4

2.56e-03221012C0035078
DiseaseBehcet Syndrome

ICAM1 TLR4

3.05e-03241012C0004943
Diseasediet measurement

TCAF1 THSD7B GPATCH8 LARS2 TMCO4 NEK1 INF2 SLC25A13 WSCD2 GPC5

3.20e-03104910110EFO_0008111
DiseasePostural instability

INKA2 PRMT6

3.31e-03251012HP_0002172

Protein segments in the cluster

PeptideGeneStartEntry
KVDWLLPRAGGVGGK

FAM223B

96

A6NKX1
AQGELGWLLDPPKDG

EPHA1

36

P21709
GDWGIEKLGDTPRKK

BBX

496

Q8WY36
NKPGFGNRCLKEGWL

ABCA4

1436

P78363
NVGLALLWSEKIKGP

IBA57

316

Q5T440
LPLGGSIKQGVKSRW

DMXL2

1216

Q8TDJ6
LGQARAKLESWKEGP

DMD

2596

P11532
KIWRLNRGLEEKPGG

DTL

386

Q9NZJ0
GIWLGLELRSAKGKN

CLIP4

651

Q8N3C7
KAPRNPLAKWAVGEG

DMWD

271

Q09019
WGALPLGGKALHKEL

ACTR10

161

Q9NZ32
RGWGFCLDDIPKKKG

ADAMTS12

446

P58397
DLPKGIRGNRWKAGL

ADAP2

316

Q9NPF8
KIQWLKDAQGLPGGG

R3HDM2

896

Q9Y2K5
LAKAAGPELRVEGWK

C9orf64

36

Q5T6V5
SGGPLGQKRDPKEWI

PAFAH1B1

81

P43034
KVLREKWLLQGIPAG

PALM2

46

Q8IXS6
LKEDGVRGLAKGWAP

SLC25A3

111

Q00325
DRKKWEAGGQLVIPL

NEK1

756

Q96PY6
QVDWNKIGGDLPKGR

CHL1

271

O00533
VGNWLDLPELEKGGE

INKA2

166

Q9NTI7
GRSPKPDKWELLQLG

GPC5

471

P78333
RIPGDELKWKFISDG

HERC2

3681

O95714
WPDREKGKLLHGQNG

KIAA0319L

1016

Q8IZA0
KISWRKDGQPLPGEG

HMCN2

2201

Q8NDA2
DNNKSKPGGWLPLLL

IL17RB

281

Q9NRM6
DSKKLPGLGDPDIDW

KIAA0930

86

Q6ICG6
PNPLWDRGKIGKVEG

LBHD1

31

Q9BQE6
GEQEKAGLPLGAWRL

CCDC28A

11

Q8IWP9
ELGKQLLKTGWEGSP

IRAG1

321

Q9Y6F6
RLLQKHGWKLGQGLG

GPATCH8

46

Q9UKJ3
RQIAGKGGPWKVISL

PNMA6F

76

A0A0J9YX94
WPGAFEEGLKRLKEG

PEX5L

326

Q8IYB4
VAPWERGKGVAGLLQ

NAT16

126

Q8N8M0
KVDWLLPRAGGVGGK

FAM223A

96

Q8IWN6
VKVLDKWPLRSGGLQ

NRG2

161

O14511
NVGGLLGPAKREAWL

EYA1

451

Q99502
EKGLDGRPGQFLWEV

PDZD3

346

Q86UT5
FLWEVDPGLPAKKAG

PDZD3

356

Q86UT5
GEAALGKRLWPARGK

ALOX15

31

P16050
GWPNGLALDLQEGKL

LRP5L

121

A4QPB2
LFKKAGPGLKRWGAA

MBOAT7

21

Q96N66
DPQKGFWCQLLEGGK

NDST4

801

Q9H3R1
NGEPLVGRGLKKQWS

PITPNM2

291

Q9BZ72
GAQRKWAALKEKLGP

INF2

6

Q27J81
GNVLILAIWGDKGAP

MFSD4B

106

Q5TF39
LLGKWHSNLGARPKG

RABGAP1L

516

Q5R372
GWLLLAEAKGDAKPE

PLOD1

11

Q02809
GLVLWNLGFRIKKGP

MRGPRG

31

Q86SM5
KKDPGGLTHSGLWRI

CACNG8

76

Q8WXS5
IQPRKGGADWLGLKD

FBF1

336

Q8TES7
TLWDGKKRGDLPGEP

CABIN1

1476

Q9Y6J0
GLTELPWDGGLKRAK

GPAT3

396

Q53EU6
KERKGFNLQGPLILW

ELOVL3

56

Q9HB03
LVWRAGKDGGLPINA

CDON

596

Q4KMG0
LGKGLAALDGPKWFQ

CYP4X1

121

Q8N118
KIEDFWGPAKRLLGD

DNAH7

2731

Q8WXX0
WLKGGVVLKEDALPG

BSG

171

P35613
KWLKEGGLLLPASAE

PRMT6

176

Q96LA8
LQLIGDKWGKSGPRG

FGD2

551

Q7Z6J4
EGPGSLLSELKSKGW

IDE

341

P14735
AWGNPLPELKCLKDG

ICAM1

421

P05362
GNPGERLRKKKWDLS

DDX17

111

Q92841
IGKLKLPKGGDWRAD

C4orf54

961

D6RIA3
ENPGKLKAPLGLLDW

SLC13A2

396

Q13183
WKQSRGKGLLHGPQD

CDH15

631

P55291
LHKPRDLGWDKIGGL

PEX1

831

O43933
LKPWLGDGLLLSKGD

CYP4F22

136

Q6NT55
EEPILWTKGEILGKG

MAP3K19

1056

Q56UN5
GKAEDLGSKLLPAWI

FOCAD

1246

Q5VW36
KDEGDLRNGWLIKTP

PLEKHF2

91

Q9H8W4
LLAVLLRKGAPGQGW

ITPRIPL2

411

Q3MIP1
LRKGAPGQGWDEEHL

ITPRIPL2

416

Q3MIP1
PQGSKLELPLWLAKG

GINS3

61

Q9BRX5
RTKPGWDEKGLLLAP

TMCO4

521

Q5TGY1
LLGGWTDDKKVPGRM

SH3BP4

141

Q9P0V3
KRQLNGGPDVIKWER

LARS2

16

Q15031
NVEKGWLAKLGPDGA

TCAF1

431

Q9Y4C2
KGPDWILGEIKTSGL

NDUFV1

71

P49821
GSFLWGKPDLDKIRE

ERCC5

946

P28715
DPDWLIGERGNKKGK

SH3GLB2

371

Q9NR46
ILVDKLGLQWGRGPS

SPATA31E1

1326

Q6ZUB1
AGRPANWAPGRKKKD

PNKP

291

Q96T60
KNWGGFRIPKKGERQ

JADE1

746

Q6IE81
KEPGLLSLVDWAKSG

SETD1A

856

O15047
PAVKRLLGWKQGDEE

SMAD9

16

O15198
SPAVKRLLGWKQGDE

SMAD1

11

Q15797
REEGPKALWKGAGAR

SLC25A13

571

Q9UJS0
LEGIWSIKRNLPVGG

C11orf97

86

A0A1B0GVM6
NDLGWKLFGKAPLRE

TBC1D14

256

Q9P2M4
GRGLAGREPWSKLKQ

VWC2

81

Q2TAL6
PLVKIWNLEKRDGGN

VPS11

111

Q9H270
GPAKRPTGQKWLLDL

TRPM5

496

Q9NZQ8
WKQKSLEGRGLGLPD

PLPPR3

411

Q6T4P5
GEDRLWKVLGLPKCN

SPAG16

371

Q8N0X2
PVVILLGWGGCKDKN

TMEM53

36

Q6P2H8
GSLDGKLRLWNIPDK

WDR44

666

Q5JSH3
GEWVGLCKIDREGKP

RPS12

86

P25398
LDPPLWSQRGKGKVF

SGSM1

376

Q2NKQ1
PHVTWKLRGKDLGQG

IGSF9

166

Q9P2J2
GKLPLWAKRLLGDDD

WDR62

831

O43379
KLVELWGGKDGPVGF

XPOT

851

O43592
VGRLPFLWGKQEEGE

ZSWIM3

671

Q96MP5
SLLEQGKEPWLGKRE

ZNF140

56

P52738
PWFKGKDGNERAKLG

WSCD2

91

Q2TBF2
KGWSLQPLDPDGRVK

THSD7B

1541

Q9C0I4
WKKCLPIRGIDGNGK

UBR4

4071

Q5T4S7
LRKALLDGKSWNPEG

TLR4

811

O00206
LKPQDPSKGWDILGL

TTC31

496

Q49AM3
LWLKREAIPGEGRKA

RNF39

11

Q9H2S5
VLGWKQPDKIGGAEI

MYOM1

951

P52179